aspirin has been researched along with Central Nervous System Disease in 16 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since its introduction in the United States in 1974, ibuprofen (Motrin, Upjohn) has been shown to be safe and effective for the treatment of pain, dysmenorrhea, inflammation, and fever." | 2.65 | Safety profile: fifteen years of clinical experience with ibuprofen. ( Royer, GL; Seckman, CE; Welshman, IR, 1984) |
| " The reference dose of Diclofenac used in all randomized controlled trials is 150 mg/die; this controlled release dosage allows to decrease the number of daily administrations, ensuring a better patient compliance, especially if elderly and/or in polytherapy." | 1.40 | [Diclofenac: update on tolerableness and spinal anti-inflammatory action]. ( Sandri, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sandri, A | 1 |
| Hughes, GR | 1 |
| Royer, GL | 1 |
| Seckman, CE | 1 |
| Welshman, IR | 1 |
| Offner, H | 1 |
| Danneskiold-Samsøe, B | 1 |
| Dore-Duffy, P | 1 |
| Robinson, DR | 1 |
| Ehrlich, G | 1 |
| Gomberg, R | 1 |
| Hamm, P | 1 |
| Martin, A | 1 |
| Wasner, CK | 1 |
| Fries, JF | 1 |
| Melton, JW | 1 |
| Lussier, A | 1 |
| Ward, JR | 1 |
| Neustadt, D | 1 |
| Multz, C | 1 |
| Monson, RR | 1 |
| Hall, AP | 1 |
| Douglas, RG | 1 |
| Iobst, WF | 1 |
| Bridges, CR | 1 |
| Regan-Smith, MG | 1 |
| Schlegel, SI | 1 |
| Paulus, HE | 1 |
| Grigor, RR | 1 |
| Spitz, PW | 1 |
| Furst, DE | 1 |
| Kinsella, TD | 1 |
| MacKenzie, KR | 1 |
| Kim, SO | 1 |
| Johnson, LG | 1 |
| Barer, J | 1 |
| Hill, LL | 1 |
| Hill, RM | 1 |
| Martinez, WM | 1 |
4 reviews available for aspirin and Central Nervous System Disease
| Article | Year |
|---|---|
The treatment of SLE: the case of conservative management.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antimalarials; Arthriti | 1982 |
Prostaglandins and anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Central Nervous System Diseases; Cyclic AMP; Drug Hypers | 1983 |
Antirheumatic agents: CNS toxicity and its avoidance.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Central Nervous Sy | 1989 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen | 1986 |
3 trials available for aspirin and Central Nervous System Disease
| Article | Year |
|---|---|
Safety profile: fifteen years of clinical experience with ibuprofen.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Proteins; Centra | 1984 |
Naproxen vs. aspirin in osteoarthritis of the hip and knee.
Topics: Adult; Aged; Aspirin; Central Nervous System Diseases; Clinical Trials as Topic; Double-Blind Method | 1978 |
Evaluation of indomethacin by a controlled, cross-over technique in 30 patients with ankylosing spondylitis.
Topics: Alkaline Phosphatase; Anemia, Hypochromic; Aspartate Aminotransferases; Aspirin; Central Nervous Sys | 1967 |
9 other studies available for aspirin and Central Nervous System Disease
| Article | Year |
|---|---|
[Diclofenac: update on tolerableness and spinal anti-inflammatory action].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood-Brain Barrier; Car | 2014 |
Effect of prostaglandins and aspirin on active E-rosette formation in patients with multiple sclerosis.
Topics: Adult; Aged; Alprostadil; Arthritis, Rheumatoid; Aspirin; Central Nervous System Diseases; Cyclic AM | 1982 |
Primary drug therapy: aspirin vs. the nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Central Nervous System Diseases; Chemical and Drug Ind | 1983 |
Mucocutaneous lymph node syndrome (Kawasaki disease) in an adult.
Topics: Adult; Anti-Bacterial Agents; Arteritis; Aspirin; Cardiovascular Diseases; Central Nervous System Di | 1981 |
Treatment decisions in systemic lupus erythematosus.
Topics: Arthritis; Aspirin; Central Nervous System Diseases; Decision Making; Humans; Immunosuppressive Agen | 1980 |
Mortality among arthritics.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Cardiovascular Diseases; Central Nervous System Diseases; Coro | 1976 |
Influenza: the disease and its complications.
Topics: Amantadine; Aspirin; Bacterial Infections; Bronchitis; Central Nervous System Diseases; Cross Infect | 1976 |
Salicylate toxicity in elderly patients with rheumatoid arthritis.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Central Nervous System Diseases; Dose-Resp | 1987 |
Fatal poisoning from salt used as an emetic.
Topics: Aspirin; Blood Glucose; Blood Urea Nitrogen; Central Nervous System Diseases; Child, Preschool; Chlo | 1973 |