aspirin has been researched along with Carotid Artery Thrombosis in 63 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Carotid Artery Thrombosis: Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The in vivo antithrombotic property of ibudilast (CAS 50847-11-5), a phosphodiesterase 4 (PDE4) inhibitor, was evaluated in a photochemically-induced guinea pig carotid artery thrombosis model in combination with low-dose ASA." | 7.78 | Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. ( Hoshina, K; Manita, S; Matsuzawa, S; Miyata, Y; Ooie, T; Sasahara, T; Sueyoshi, S; Yasue, T, 2012) |
| "We determined the effects of aspirin and a novel thromboxane A2/prostaglandin endoperoxide (TP)-receptor antagonist, BMS-180291, on thrombosis and bleeding times in skin and mesenteric arteries." | 7.68 | Superior activity of a thromboxane receptor antagonist as compared with aspirin in rat models of arterial and venous thrombosis. ( Heran, CL; Ogletree, ML; Schumacher, WA; Steinbacher, TE; Youssef, S, 1993) |
| "The aspirin was started before operation and continued for 6 weeks after operation, at which time the endarterectomized vessels were excised." | 5.27 | Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model. ( Bush, HL; Jakubowski, JA; Sentissi, JM, 1988) |
| "ASP6537 functions as a highly selective COX-1 inhibitor with a superior ability to aspirin for normalizing TXA2/PGI2 balance, and exerts antithrombotic effect without ulcerogenic effect." | 3.79 | ASP6537, a novel highly selective cyclooxygenase-1 inhibitor, exerts potent antithrombotic effect without "aspirin dilemma". ( Abe, M; Funatsu, T; Kato, Y; Kawasaki, T; Morita, Y; Ohmiya, M; Okada, M; Sakata, C; Suzuki, K, 2013) |
| " The in vivo antithrombotic property of ibudilast (CAS 50847-11-5), a phosphodiesterase 4 (PDE4) inhibitor, was evaluated in a photochemically-induced guinea pig carotid artery thrombosis model in combination with low-dose ASA." | 3.78 | Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. ( Hoshina, K; Manita, S; Matsuzawa, S; Miyata, Y; Ooie, T; Sasahara, T; Sueyoshi, S; Yasue, T, 2012) |
| "The objective of this study was to determine if orally-administered PD0348292, a direct specific factor Xa inhibitor, inhibits thrombosis following porcine carotid arterial injury comparably to aspirin or clopidogrel alone or in combination." | 3.74 | Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. ( Baxi, S; Karnicki, K; Leadley, RJ; McBane, RD; Peterson, T; Wysokinski, W, 2008) |
| "The model of electrically stimulated carotid artery thrombosis in Sprague Dawley rats was used; the effects of copper-aspirin complex on rat platelet-neutrophil adhesion and platelet aggregation stimulated by activated neutrophils were observed by rosette assay and Born's method, respectively." | 3.72 | Effects of copper-aspirin complex on platelet-neutrophil interactions. ( Chen, P; Li, L; Liu, WP; Shen, ZQ, 2004) |
| " Treatment with aspirin, heparin, or the combination of aspirin plus heparin was ineffective for the prevention of carotid artery thrombosis in this model." | 3.69 | Chimeric 7E3 prevents carotid artery thrombosis in cynomolgus monkeys. ( Cunningham, MR; Lucchesi, BR; Manley, PJ; Mu, DX; Nedelman, MA; Rote, WE; Weisman, H, 1994) |
| "We determined the effects of aspirin and a novel thromboxane A2/prostaglandin endoperoxide (TP)-receptor antagonist, BMS-180291, on thrombosis and bleeding times in skin and mesenteric arteries." | 3.68 | Superior activity of a thromboxane receptor antagonist as compared with aspirin in rat models of arterial and venous thrombosis. ( Heran, CL; Ogletree, ML; Schumacher, WA; Steinbacher, TE; Youssef, S, 1993) |
| " In addition, the antithrombotic effects of SK&F 106760 were compared with those of aspirin in an acute canine model of extracranial carotid artery thrombosis with high-grade stenosis." | 3.68 | Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis. ( Feuerstein, GZ; Nichols, AJ; Ohlstein, EH; Rycyna, R; Sarkar, S; Sauermelch, CF; Willette, RN, 1992) |
| "The difference in the effectiveness of aspirin for the prevention of stroke and secondary prevention of myocardial infarction was discussed on the basis of inhibition of platelet aggregation." | 3.67 | Experimental basis of platelet aggregation inhibition by acetylsalicylic acid. ( Begent, NA; Born, GV; Görög, P, 1984) |
| "In children and young adults, amaurosis fugax is a benign condition." | 2.38 | Atherosclerotic carotid disease and the eye. ( Breen, LA, 1991) |
| "Dual treatment with aspirin (5 mg kg(-1) ) and clopidogel (0." | 1.43 | A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel. ( Chu, L; Desai, K; Gutstein, DE; Kurowski, S; Seiffert, D; Wang, X; Wu, W; Zhou, X, 2016) |
| " We evaluated apixaban, a direct and highly selective factor Xa inhibitor, in combination with clinically relevant doses of aspirin and/or clopidogrel for prevention of arterial thrombosis in rabbits." | 1.35 | Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits. ( Crain, EJ; Watson, CA; Wong, PC, 2008) |
| "Her blood test indicated existence of antiphospholipid antibody syndrome (APS) complicated with mixed connective tissue disease as an etiology of this uncommon carotid thrombus." | 1.32 | [Embolic stroke with mobile thrombus in carotid artery induced by antiphospholipid antibody syndrome]. ( Fujimoto, S; Hagiwara, N; Nishimura, Y; Okada, Y; Toyoda, K, 2003) |
| "2." | 1.31 | Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796. ( Driscoll, EM; Giboulot, TA; Hennan, JK; Hong, TT; Lucchesi, BR; Willens, DE, 2002) |
| "However, only r-hirudin inhibited thrombus formation at a therapeutical prolongation of aPTT, while heparin required supratherapeutical amounts to achieve the same inhibition." | 1.30 | A technique to investigate microvascular mural thrombus formation in arteries and veins: II. Effects of aspirin, heparin, r-hirudin, and G-4120. ( Hoylaerts, MF; Nyström, A; Stassen, JM; Stockmans, F; Vermylen, J, 1997) |
| "To examine whether the dosage of a platelet-suppressive agent at which an antithrombotic effect is adequate and bleeding tendency is not increased can be found, the antithrombotic effects, antiplatelet effects and bleeding times of ticlopidine and aspirin were investigated in the rat experimental thrombus formation model." | 1.29 | Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model. ( Kakishita, E; Oura, Y; Suehiro, A; Ueda, M, 1994) |
| "Most of cerebral infarctions were observed in the hemisphere, ipsilateral to the irradiated carotid artery." | 1.29 | Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits. ( Fujimura, M; Mikashima, H, 1993) |
| "The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model." | 1.28 | Dose-response of rt-PA and its combination with aspirin in a rat embolic stroke model. ( Boysen, G; Overgaard, K; Pedersen, H; Sereghy, T, 1992) |
| "Flunarizine was as effective as aspirin in inhibiting platelet adhesion and fibrin cord formation." | 1.28 | Effect of flunarizine on arterial thrombosis after endarterectomy in rats. ( Handa, Y; Hayashi, M; Kabuto, M; Kawano, H; Kobayashi, H; Kobayashi, S, 1989) |
| "Although it is widely accepted that aspirin inhibits platelet aggregation in arterial thrombosis, the appropriate dosage of aspirin remains quite controversial." | 1.27 | Effect of different aspirin doses on arterial thrombosis after canine carotid endarterectomy: a scanning electron microscope and indium-111-labeled platelet study. ( Burke, JC; Chandler, WF; Ercius, MS; Ford, JW; Swanson, DP, 1984) |
| "The aspirin was started before operation and continued for 6 weeks after operation, at which time the endarterectomized vessels were excised." | 1.27 | Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model. ( Bush, HL; Jakubowski, JA; Sentissi, JM, 1988) |
| "Eight patients with transient ischemic attacks, and three with partial nonprogressive strokes associated with mitral valve prolapse, are reported." | 1.26 | TIA, stroke, and mitral valve prolapse. ( Watson, RT, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (31.75) | 18.7374 |
| 1990's | 20 (31.75) | 18.2507 |
| 2000's | 11 (17.46) | 29.6817 |
| 2010's | 10 (15.87) | 24.3611 |
| 2020's | 2 (3.17) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 1 |
| Jang, HJ | 1 |
| Schellingerhout, D | 1 |
| Lee, SK | 1 |
| Kim, H | 1 |
| Kim, YD | 1 |
| Lee, KY | 1 |
| Choi, HY | 1 |
| Cho, HJ | 1 |
| Jang, SS | 1 |
| Jeon, S | 1 |
| Kwon, IC | 1 |
| Kim, K | 1 |
| Ryu, WS | 1 |
| Nahrendorf, M | 1 |
| Choi, S | 1 |
| Kim, DE | 1 |
| Belcher, A | 1 |
| Zulfiker, AHM | 1 |
| Li, OQ | 1 |
| Yue, H | 1 |
| Gupta, AS | 1 |
| Li, W | 1 |
| Spasov, AA | 2 |
| Kucheryavenko, AF | 2 |
| Sirotenko, VS | 1 |
| Gaidukova, KA | 1 |
| Morkovnik, AS | 1 |
| Anisimova, VA | 2 |
| Divaeva, LN | 1 |
| Kuz'menko, TA | 1 |
| Yi, TY | 1 |
| Chen, WH | 1 |
| Wu, YM | 1 |
| Zhang, MF | 1 |
| Lin, DL | 1 |
| Lin, XH | 1 |
| Sakata, C | 1 |
| Kawasaki, T | 1 |
| Kato, Y | 1 |
| Abe, M | 1 |
| Suzuki, K | 1 |
| Ohmiya, M | 1 |
| Funatsu, T | 1 |
| Morita, Y | 1 |
| Okada, M | 1 |
| Ofosu, FA | 1 |
| Kosolapov, VA | 1 |
| Köklü, E | 2 |
| Arslan, Ş | 2 |
| Yüksel, İÖ | 2 |
| Bayar, N | 2 |
| Koç, P | 1 |
| Zhou, X | 1 |
| Kurowski, S | 1 |
| Wu, W | 1 |
| Desai, K | 1 |
| Chu, L | 1 |
| Gutstein, DE | 1 |
| Seiffert, D | 1 |
| Wang, X | 1 |
| Wong, PC | 4 |
| Watson, CA | 4 |
| Crain, EJ | 4 |
| Hanhart, J | 1 |
| Koskas, P | 1 |
| Obadia, M | 1 |
| Le Mer, Y | 1 |
| Sahel, JA | 1 |
| Paques, M | 1 |
| Matsuzawa, S | 1 |
| Hoshina, K | 1 |
| Sueyoshi, S | 1 |
| Miyata, Y | 1 |
| Manita, S | 1 |
| Ooie, T | 1 |
| Yasue, T | 1 |
| Sasahara, T | 1 |
| Vellimana, AK | 1 |
| Kadkhodayan, Y | 1 |
| Rich, KM | 1 |
| Cross, DT | 1 |
| Moran, CJ | 1 |
| Zazulia, AR | 1 |
| Lee, JM | 1 |
| Chicoine, MR | 1 |
| Dacey, RG | 1 |
| Derdeyn, CP | 1 |
| Zipfel, GJ | 1 |
| Hennan, JK | 1 |
| Hong, TT | 2 |
| Willens, DE | 1 |
| Driscoll, EM | 1 |
| Giboulot, TA | 1 |
| Lucchesi, BR | 3 |
| Zaspel, AM | 1 |
| Wright, MR | 2 |
| Lam, PY | 1 |
| Pinto, DJ | 1 |
| Wexler, RR | 2 |
| Knabb, RM | 2 |
| Hagiwara, N | 1 |
| Nishimura, Y | 1 |
| Toyoda, K | 1 |
| Fujimoto, S | 1 |
| Okada, Y | 1 |
| Shen, ZQ | 1 |
| Chen, P | 2 |
| Li, L | 1 |
| Liu, WP | 1 |
| Huang, J | 1 |
| Driscoll, E | 1 |
| Jiang, X | 1 |
| Hua, J | 1 |
| Bostwick, JS | 1 |
| Ogletree, ML | 2 |
| Schumacher, WA | 3 |
| Rehfuss, R | 1 |
| Karnicki, K | 1 |
| Leadley, RJ | 1 |
| Baxi, S | 1 |
| Peterson, T | 1 |
| Wysokinski, W | 1 |
| McBane, RD | 1 |
| Born, GV | 2 |
| Görög, P | 1 |
| Begent, NA | 1 |
| Eichner, ER | 1 |
| Easton, JD | 1 |
| Hart, RG | 1 |
| Sherman, DG | 1 |
| Kaste, M | 1 |
| Ercius, MS | 1 |
| Chandler, WF | 1 |
| Ford, JW | 1 |
| Swanson, DP | 1 |
| Burke, JC | 1 |
| Gryglewski, RJ | 1 |
| Philp, RB | 3 |
| Paul, ML | 1 |
| Randall, MJ | 1 |
| Wilding, RI | 1 |
| Buchanan, MR | 1 |
| Dejana, E | 1 |
| Gent, M | 1 |
| Mustard, JF | 1 |
| Hirsch, J | 1 |
| Heran, CL | 2 |
| Steinbacher, TE | 2 |
| Youssef, S | 1 |
| Bernat, A | 1 |
| Mares, AM | 1 |
| Defreyn, G | 1 |
| Maffrand, JP | 1 |
| Herbert, JM | 1 |
| Roux, S | 1 |
| Carteaux, JP | 1 |
| Hess, P | 1 |
| Falivene, L | 1 |
| Clozel, JP | 1 |
| Suehiro, A | 1 |
| Oura, Y | 1 |
| Ueda, M | 1 |
| Kakishita, E | 1 |
| Rote, WE | 1 |
| Nedelman, MA | 1 |
| Mu, DX | 1 |
| Manley, PJ | 1 |
| Weisman, H | 1 |
| Cunningham, MR | 1 |
| Megill, JR | 1 |
| Durham, SK | 1 |
| Freund, M | 1 |
| Mantz, F | 1 |
| Nicolini, P | 1 |
| Gachet, C | 1 |
| Mulvihill, J | 1 |
| Meyer, L | 1 |
| Beretz, A | 1 |
| Cazenave, JP | 1 |
| Fujimura, M | 1 |
| Mikashima, H | 1 |
| Huang, ZS | 1 |
| Teng, CM | 1 |
| Lee, TK | 1 |
| Shun, CT | 1 |
| Wang, CY | 1 |
| Gould, RJ | 1 |
| Black, K | 1 |
| Pavlakis, SG | 1 |
| Stockmans, F | 1 |
| Stassen, JM | 1 |
| Vermylen, J | 1 |
| Hoylaerts, MF | 1 |
| Nyström, A | 1 |
| Aoki, T | 1 |
| Cox, D | 1 |
| Senzaki, K | 1 |
| Seki, J | 1 |
| Tanaka, A | 1 |
| Takasugi, H | 1 |
| Motoyama, Y | 1 |
| Krekora, K | 1 |
| De Curtis, A | 1 |
| Polishchuck, R | 1 |
| Donati, MB | 1 |
| Iacoviello, L | 1 |
| Meade, RP | 1 |
| Quan, ML | 1 |
| Slee, AM | 1 |
| Lee, KS | 1 |
| Suh, JD | 1 |
| Han, SB | 1 |
| Yoo, JC | 1 |
| Lee, SJ | 1 |
| Cho, SJ | 1 |
| Bream, ML | 1 |
| Ferguson, GG | 1 |
| Seuter, F | 1 |
| Busse, WD | 1 |
| Watson, RT | 1 |
| Mohr, JP | 1 |
| Francey, I | 1 |
| Warren, BA | 1 |
| Koike, T | 1 |
| Minakawa, T | 1 |
| Abe, H | 1 |
| Takeuchi, S | 1 |
| Sasaki, O | 1 |
| Nishimaki, K | 1 |
| Tanaka, R | 1 |
| Overgaard, K | 1 |
| Sereghy, T | 1 |
| Pedersen, H | 1 |
| Boysen, G | 1 |
| Willette, RN | 1 |
| Sauermelch, CF | 1 |
| Rycyna, R | 1 |
| Sarkar, S | 1 |
| Feuerstein, GZ | 1 |
| Nichols, AJ | 1 |
| Ohlstein, EH | 1 |
| Breen, LA | 1 |
| Prager, M | 2 |
| Pratschner, T | 2 |
| Wenzl, E | 1 |
| Polterauer, P | 2 |
| Ehringer, H | 2 |
| Kretschmer, G | 1 |
| Wille, B | 1 |
| Fischer, M | 1 |
| Alexander, K | 1 |
| Edwards, WH | 2 |
| Mulherin, JL | 1 |
| Jenkins, JM | 1 |
| Kobayashi, H | 1 |
| Hayashi, M | 1 |
| Kawano, H | 1 |
| Handa, Y | 1 |
| Kabuto, M | 1 |
| Kobayashi, S | 1 |
| Orekhov, AN | 2 |
| Belyaev, AA | 1 |
| Orekhova, NM | 2 |
| Smirnov, MD | 1 |
| Samokhin, GP | 2 |
| Ragimov, SE | 2 |
| Akchurin, RS | 1 |
| Smirnov, VN | 1 |
| Bush, HL | 1 |
| Jakubowski, JA | 1 |
| Sentissi, JM | 1 |
| Rossmann, E | 1 |
| Beliaev, AA | 1 |
| Vroom, FQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Postoperative Prostaglandin E1 in Head and Neck Microsurgery[NCT00733434] | Phase 4 | 242 participants (Anticipated) | Interventional | 2008-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Carotid Artery Thrombosis
| Article | Year |
|---|---|
Platelets, carotids, and coronaries. Critique on antithrombotic role of antiplatelet agents, exercise, and certain diets.
Topics: Angina Pectoris; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Carotid Artery Thrombosi | 1984 |
Prostaglandins, platelets, and atherosclerosis.
Topics: Animals; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Circulation; Blood Vessels; Carotid Art | 1980 |
Atherosclerotic carotid disease and the eye.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Blindness; Carotid Artery Diseas | 1991 |
Aspirin and platelets in relation to cerebrovascular disease.
Topics: Animals; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Cerebrovascular Diso | 1990 |
1 trial available for aspirin and Carotid Artery Thrombosis
| Article | Year |
|---|---|
Another Endovascular Therapy Strategy for Acute Tandem Occlusion: Protect-Expand-Aspiration-Revascularization-Stent (PEARS) Technique.
Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Cerebral Revascul | 2018 |
58 other studies available for aspirin and Carotid Artery Thrombosis
| Article | Year |
|---|---|
Short-Term Cessation of Dabigatran Causes a Paradoxical Prothrombotic State.
Topics: Aged; Aged, 80 and over; Animals; Antithrombins; Arachidonic Acid; Aspirin; Carotid Artery Thrombosi | 2021 |
Targeting Thymidine Phosphorylase With Tipiracil Hydrochloride Attenuates Thrombosis Without Increasing Risk of Bleeding in Mice.
Topics: Animals; Aspirin; Blood Platelets; Carotid Artery Thrombosis; Chlorocebus aethiops; COS Cells; Disea | 2021 |
Antithrombotic Activity of DAB-15, a Novel Diazepinobenzimidazole Compound.
Topics: Administration, Oral; Animals; Aspirin; Azepines; Benzimidazoles; Carotid Artery Thrombosis; Drug Ev | 2017 |
ASP6537, a novel highly selective cyclooxygenase-1 inhibitor, exerts potent antithrombotic effect without "aspirin dilemma".
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epoprosten | 2013 |
Effective, selective and specific inhibition of COX-1 may overcome the "aspirin paradox".
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Fibrinolyt | 2013 |
Antithrombogenic activity of antioxidant compounds.
Topics: Animals; Animals, Outbred Strains; Anticoagulants; Antioxidants; Aspirin; Benzimidazoles; Carotid Ar | 2013 |
Acute Carotid Artery Stent Thrombosis Due to Dual Antiplatelet Resistance.
Topics: Acute Disease; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Clopidogrel; Drug | 2015 |
Is Acute Carotid Artery Stent Thrombosis an Avoidable Complication?
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Artery Thrombosis; Cerebral Angiography; Clopidogrel; Fema | 2015 |
A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Chlorides; Clopidogrel; Disease Models, Animal; Drug Ev | 2016 |
Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits.
Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Clopidogrel; Drug Therapy, Combination; | 2008 |
[Brain hypoperfusion revealed by an ocular ischemic syndrome].
Topics: Antihypertensive Agents; Aspirin; Atorvastatin; Brain Ischemia; Carotid Artery Thrombosis; Ciliary B | 2008 |
Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Drug Thera | 2012 |
Symptomatic patients with intraluminal carotid artery thrombus: outcome with a strategy of initial anticoagulation.
Topics: Adult; Aged; Anticoagulants; Aspirin; Brain Ischemia; Carotid Arteries; Carotid Artery Thrombosis; C | 2013 |
Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796.
Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Constriction, Pathologic; Coronary Throm | 2002 |
Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits.
Topics: Administration, Oral; Animals; Antithrombin III; Aspirin; Bleeding Time; Blood Flow Velocity; Caroti | 2002 |
[Embolic stroke with mobile thrombus in carotid artery induced by antiphospholipid antibody syndrome].
Topics: Antiphospholipid Syndrome; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Common; Female; Follo | 2003 |
Effects of copper-aspirin complex on platelet-neutrophil interactions.
Topics: Animals; Aspirin; Blood Platelets; Carotid Artery Thrombosis; Cell Adhesion; Copper; Drug Combinatio | 2004 |
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
Topics: Animals; Aspirin; Azetidines; Benzylamines; Bleeding Time; Blood Flow Velocity; Blood Pressure; Caro | 2005 |
Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Aspirin; Biomarkers; Bleeding Time; Blood Plat | 2007 |
Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.
Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; C | 2008 |
Experimental basis of platelet aggregation inhibition by acetylsalicylic acid.
Topics: Adenosine Diphosphate; Aspirin; Carotid Artery Thrombosis; Cerebral Infarction; Coronary Circulation | 1984 |
Diagnosis and management of ischemic stroke. Part I.--Threatened stroke and its management.
Topics: Anticoagulants; Arrhythmias, Cardiac; Aspirin; Brain Ischemia; Carotid Artery Thrombosis; Cerebral A | 1983 |
Effect of different aspirin doses on arterial thrombosis after canine carotid endarterectomy: a scanning electron microscope and indium-111-labeled platelet study.
Topics: Animals; Aspirin; Carotid Arteries; Carotid Artery Thrombosis; Dogs; Dose-Response Relationship, Dru | 1984 |
Non-interference by salicylate with aspirin inhibition of arterial thrombosis in rats.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Cyclooxygenase Inhibitors; Drug Interactions; Male; Rat | 1981 |
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01).
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Aspirin; Carotid Artery Thrombosis; Cells, Cul | 1982 |
Enhanced platelet accumulation onto injured carotid arteries in rabbits after aspirin treatment.
Topics: Animals; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Carotid Artery Thrombo | 1981 |
Superior activity of a thromboxane receptor antagonist as compared with aspirin in rat models of arterial and venous thrombosis.
Topics: Animals; Aspirin; Bleeding Time; Bridged Bicyclo Compounds, Heterocyclic; Carotid Artery Thrombosis; | 1993 |
Effect of various antiplatelet agents on acute arterial thrombosis in the rat.
Topics: Acute Disease; Amino Acid Sequence; Animals; Aspirin; Carotid Artery Thrombosis; Clopidogrel; Electr | 1993 |
Experimental carotid thrombosis in the guinea pig.
Topics: Acetates; Animals; Aspirin; Biomechanical Phenomena; Blood Flow Velocity; Blood Pressure; Carotid Ar | 1994 |
Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model.
Topics: Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Disease Models, Animal; Male; Platelet A | 1994 |
Chimeric 7E3 prevents carotid artery thrombosis in cynomolgus monkeys.
Topics: Abciximab; Animals; Antibodies, Monoclonal; Aspirin; Blood Coagulation; Blood Pressure; Carotid Arte | 1994 |
Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Aspirin; Azepines; Bridged Bicyclo Compounds, Heterocyclic | 1993 |
Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition.
Topics: Animals; Anticoagulants; Arterio-Arterial Fistula; Aspirin; Carotid Artery Thrombosis; Clopidogrel; | 1993 |
Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Carotid Stenosis; Cerebral Infarction; Disease Models, | 1993 |
Combined use of aspirin and heparin inhibits in vivo acute carotid thrombosis.
Topics: Animals; Aspirin; Carotid Arteries; Carotid Artery Thrombosis; Disease Models, Animal; Drug Combinat | 1993 |
Neonatal cerebral arterial thrombosis: protein C deficiency.
Topics: Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Female; Humans; Infant, Newborn; Magne | 1996 |
A technique to investigate microvascular mural thrombus formation in arteries and veins: II. Effects of aspirin, heparin, r-hirudin, and G-4120.
Topics: Animals; Anticoagulants; Aspirin; Carotid Artery Thrombosis; Cricetinae; Disease Models, Animal; Dos | 1997 |
Comparison of the antithrombotic effects of FK633, GPIIb/IIIa antagonist, and aspirin in a guinea pig thrombosis model.
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Dipeptides; Fibrinolytic Agents; Guinea Pigs; Injection | 1998 |
An alternative model of carotid artery thrombosis in rats.
Topics: Animals; Aspirin; Blood Cell Count; Carotid Artery Thrombosis; Catheterization; Disease Models, Anim | 1999 |
Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis.
Topics: Animals; Aspirin; Blood Pressure; Boron Compounds; Carotid Artery Thrombosis; Factor Xa Inhibitors; | 2000 |
The effect of aspirin and prostaglandin E(1) on the patency of microvascular anastomosis in the rats.
Topics: Administration, Oral; Alprostadil; Anastomosis, Surgical; Animals; Aspirin; Carotid Arteries; Caroti | 2001 |
Antiplatelet drugs in a rat microsurgical model of arterial thrombosis.
Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Carotid Artery Thrombosis; Dipyridamole; Disea | 1979 |
Arachidonic acid induced mortality in animals - an appropriate model for the evaluation of antithrombotic drugs?
Topics: Animals; Anti-Inflammatory Agents; Antithrombins; Arachidonic Acids; Aspirin; Carotid Artery Thrombo | 1979 |
TIA, stroke, and mitral valve prolapse.
Topics: Adult; Aged; Aspirin; Carotid Artery Thrombosis; Cerebrovascular Disorders; Dipyridamole; Echocardio | 1979 |
Transient ischemic attacks and the prevention of strokes.
Topics: Anticoagulants; Aspirin; Carotid Artery Thrombosis; Cerebrovascular Disorders; Endarterectomy; Femal | 1978 |
Comparison of antithrombotic activity of heparin, ASA, sulfinpyrazone and VK 744 in a rat model of arterial thrombosis.
Topics: Animals; Aspirin; Blood Coagulation; Carotid Arteries; Carotid Artery Thrombosis; Disease Models, An | 1978 |
PTA of supra-aortic arteries with temporary balloon occlusion to avoid distal embolism.
Topics: Adult; Angioplasty, Balloon; Aortic Valve Stenosis; Aspirin; Brain Diseases; Carotid Artery Thrombos | 1992 |
Dose-response of rt-PA and its combination with aspirin in a rat embolic stroke model.
Topics: Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Carotid Artery Thrombosis; Cerebral Angiograph | 1992 |
Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis.
Topics: Animals; Aspirin; Blood Platelets; Carotid Artery Thrombosis; Carotid Stenosis; Cerebrovascular Circ | 1992 |
[Effect of postoperative aggregation inhibiting therapy following carotid thrombendarterectomy on patient survival. Analysis after more than 15 years follow-up].
Topics: Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Combined Modality Therapy; Endarterect | 1991 |
[Late results following thrombendarterectomy of the carotid artery].
Topics: Aged; Aspirin; Carotid Artery Thrombosis; Endarterectomy; Female; Humans; Male; Middle Aged; Postope | 1990 |
The role of antiplatelet drugs in carotid reconstructive surgery.
Topics: Adult; Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Dextrans; Dipyridamole; D | 1985 |
Effect of flunarizine on arterial thrombosis after endarterectomy in rats.
Topics: Animals; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Cell Adhesion; Endar | 1989 |
Prevention of experimental carotid artery thrombosis by magnetic vectoring of aspirin.
Topics: Animals; Aspirin; Blood Circulation; Carotid Artery Thrombosis; Dogs; Erythrocytes; Ferric Compounds | 1987 |
Early healing after carotid endarterectomy: effect of high- and low-dose aspirin on thrombosis and early neointimal hyperplasia in a nonhuman primate model.
Topics: Animals; Aspirin; Bleeding Time; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Endar | 1988 |
[Effect of aggregation inhibitors on patient survival following thrombendarterectomy of the internal carotid artery].
Topics: Aged; Aspirin; Carotid Artery Thrombosis; Carotid Artery, Internal; Combined Modality Therapy; Endar | 1988 |
[Local prevention of thrombosis in the dog carotid artery using magnetically concentrated erythrocytes loaded with aspirin].
Topics: Animals; Aspirin; Carotid Artery Thrombosis; Dogs; Erythrocytes; Magnetics; Male | 1987 |
Treatment of stroke: medical or surgical?
Topics: Angiography; Antihypertensive Agents; Aspirin; Blood Pressure; Carotid Arteries; Carotid Artery Thro | 1974 |