Page last updated: 2024-10-23

aspirin and Carotid Arteriopathies, Traumatic

aspirin has been researched along with Carotid Arteriopathies, Traumatic in 20 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"This produced an occlusive thrombus in all vehicle-treated ferrets within 41 +/- 3 min with an average weight of 8 +/- 1 mg (n = 7)."5.29A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin. ( Durham, SK; Megill, JR; Schumacher, WA; Steinbacher, TE, 1996)
"The objective of this study was to determine if orally-administered PD0348292, a direct specific factor Xa inhibitor, inhibits thrombosis following porcine carotid arterial injury comparably to aspirin or clopidogrel alone or in combination."3.74Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. ( Baxi, S; Karnicki, K; Leadley, RJ; McBane, RD; Peterson, T; Wysokinski, W, 2008)
"Recurrent epistaxis is a rare presentation of internal carotid artery C4/C5 segment pseudo-aneurysm rupture."1.40Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report. ( Bazina, A; Hucika, Z; Mišmaš, A; Pavliša, G; Poljaković, Z, 2014)
"Blunt carotid artery injuries (BCI) are being recognized and treated with increasing frequency because of improved screening protocols."1.35Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm. ( Berne, JD; McGovern, TM; Norwood, SH; Reuland, KR; Rowe, SA; Villarreal, DH, 2008)
"Assessment of platelet-thrombus formation with this technique was more sensitive than change in flow in determining antithrombotic efficacy, and thrombus formation was detected earlier."1.31In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector. ( Badimon, JJ; Chesebro, JH; Fallon, JT; Fuster, V; Gallo, R; Helft, G; Osende, JI; Padurean, A; Rodriguez, OX; Worthley, SG; Zaman, AG, 2000)
"Thrombocytopenia was produced by a polyclonal antiplatelet serum that depleted circulating platelet count by 84% without influencing neutrophil count."1.30Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs. ( Guidoin, R; Latour, JG; Merhi, Y; Provost, P, 1997)
"Aspirin treatment in combination with neutropenia produced a 50% reduction in whole blood platelet aggregation, resulted in a significant inhibition of platelet deposition to deeply injured arteries, and decreased vasoconstriction by 66% to 15."1.29Neutrophil implications in platelet deposition and vasoconstriction after deep arterial injury by angioplasty in pigs. ( Lacoste, LL; Lam, JY; Merhi, Y, 1994)
"This produced an occlusive thrombus in all vehicle-treated ferrets within 41 +/- 3 min with an average weight of 8 +/- 1 mg (n = 7)."1.29A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin. ( Durham, SK; Megill, JR; Schumacher, WA; Steinbacher, TE, 1996)
"However, their effects on thrombus formation have rarely been evaluated in experimental animals in vivo."1.29In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis. ( Iwamoto, Y; Naritomi, H; Nishimura, H; Sugita, M; Tachibana, H, 1996)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's8 (40.00)18.2507
2000's7 (35.00)29.6817
2010's2 (10.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Catapano, JS1
Israr, S1
Whiting, AC1
Hussain, OM1
Snyder, LA1
Albuquerque, FC1
Ducruet, AF1
Nakaji, P1
Lawton, MT1
Weinberg, JA1
Zabramski, JM1
Poli, L1
Mardighian, D1
Gamba, M1
Padovani, A1
Pezzini, A1
Bazina, A1
Mišmaš, A1
Hucika, Z1
Pavliša, G1
Poljaković, Z1
Ishii, A1
Viñuela, F1
Murayama, Y1
Yuki, I1
Nien, YL1
Yeh, DT1
Vinters, HV1
Berne, JD1
Reuland, KR1
Villarreal, DH1
McGovern, TM1
Rowe, SA1
Norwood, SH1
Karnicki, K1
Leadley, RJ1
Baxi, S1
Peterson, T1
Wysokinski, W1
McBane, RD1
Buchanan, MR1
Dejana, E1
Gent, M1
Mustard, JF1
Hirsch, J1
Merhi, Y2
Lacoste, LL1
Lam, JY2
Colella, JJ1
Diamond, DL1
Schumacher, WA1
Steinbacher, TE1
Megill, JR1
Durham, SK1
Nishimura, H1
Naritomi, H1
Iwamoto, Y1
Tachibana, H1
Sugita, M1
Provost, P1
Guidoin, R1
Latour, JG1
Hoffmann, P1
Bernat, A1
Savi, P1
Herbert, JM1
Zaman, AG1
Osende, JI1
Chesebro, JH2
Fuster, V2
Padurean, A1
Gallo, R1
Worthley, SG1
Helft, G1
Rodriguez, OX1
Fallon, JT1
Badimon, JJ1
Ragni, M1
Golino, P1
Cirillo, P1
Scognamiglio, A1
Piro, O1
Esposito, N1
Battaglia, C1
Botticella, F1
Ponticelli, P1
Ramunno, L1
Chiariello, M1
Prieto, AR1
Ma, H1
Huang, R1
Khan, G1
Schwartz, KA1
Hage-Korban, EE1
Schmaier, AH1
Davis, JM1
Hasan, AA1
Abela, GS1
Elliott, MA1
Taylor, LP1
Cooley, BC1
Li, X1
Dzwierzynski, W1
Gruel, SM1
Hall, RL1
Wright, RR1
O'Brien, EM1
Fagan, D1
Hanel, DP1
Gould, JS1
Völker, W1
Faber, V1
Steele, PM1
Badimon, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot, Non-masked, Randomized Clinical Trial for Evaluation of Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).[NCT05868525]Phase 498 participants (Anticipated)Interventional2024-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

20 other studies available for aspirin and Carotid Arteriopathies, Traumatic

ArticleYear
Management of Extracranial Blunt Cerebrovascular Injuries: Experience with an Aspirin-Based Approach.
    World neurosurgery, 2020, Volume: 133

    Topics: Adolescent; Adult; Aged; Anticoagulants; Aortic Dissection; Aspirin; Carotid Artery Injuries; Caroti

2020
Short-term outcome of carotid dissecting pseudoaneurysm: is it always benign?
    Acta neurologica Belgica, 2018, Volume: 118, Issue:4

    Topics: Adult; Aortic Dissection; Aspirin; Brain; Carotid Artery Injuries; Clopidogrel; Endovascular Procedu

2018
Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2014, Volume: 20, Issue:6

    Topics: Angiography, Digital Subtraction; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Clopid

2014
Swine model of carotid artery atherosclerosis: experimental induction by surgical partial ligation and dietary hypercholesterolemia.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:9

    Topics: Angiography; Angioplasty, Balloon; Animals; Aspirin; Calcinosis; Carotid Arteries; Carotid Artery In

2006
Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm.
    The Journal of trauma, 2008, Volume: 64, Issue:2

    Topics: Accidents, Traffic; Adolescent; Adult; Aneurysm, False; Aspirin; Carotid Artery Injuries; Carotid Ar

2008
Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; C

2008
Enhanced platelet accumulation onto injured carotid arteries in rabbits after aspirin treatment.
    The Journal of clinical investigation, 1981, Volume: 67, Issue:2

    Topics: Animals; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Carotid Artery Thrombo

1981
Neutrophil implications in platelet deposition and vasoconstriction after deep arterial injury by angioplasty in pigs.
    Circulation, 1994, Volume: 90, Issue:2

    Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Carotid Artery Injuries; Neutropenia; Neut

1994
Blunt carotid injury: reassessing the role of anticoagulation.
    The American surgeon, 1996, Volume: 62, Issue:3

    Topics: Adult; Anticoagulants; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Cerebral Angiogra

1996
A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin.
    Journal of pharmacological and toxicological methods, 1996, Volume: 35, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Blood Platelet

1996
In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis.
    Stroke, 1996, Volume: 27, Issue:6

    Topics: Animals; Aspirin; Carotid Artery Diseases; Carotid Artery Injuries; Carotid Artery, Common; Cerebrov

1996
Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:6

    Topics: Angioplasty, Balloon; Animals; Aspirin; Blood Platelets; Carotid Artery Injuries; Cell Adhesion; Mic

1997
Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Aspirin; Benzylamines; Bleeding Time; Carotid Artery Injuries; Collagen; Fibrinolytic Agent

1998
In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anticoagulants; Aspirin; Blood Platelets; Ca

2000
Endogenous tissue factor pathway inhibitor modulates thrombus formation in an in vivo model of rabbit carotid artery stenosis and endothelial injury.
    Circulation, 2000, Jul-04, Volume: 102, Issue:1

    Topics: Animals; Antibodies; Aspirin; Blood Coagulation; Blood Flow Velocity; Carotid Artery Injuries; Carot

2000
Thrombostatin, a bradykinin metabolite, reduces platelet activation in a model of arterial wall injury.
    Cardiovascular research, 2002, Volume: 53, Issue:4

    Topics: Animals; Aspirin; Blood Platelets; Bradykinin; Carotid Arteries; Carotid Artery Injuries; Carotid St

2002
"Shiatsu sympathectomy": ICA dissection associated with a shiatsu massager.
    Neurology, 2002, Apr-23, Volume: 58, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carotid Artery Injuries; Female; Headache; Humans;

2002
The de-endothelialized rat carotid arterial graft: a versatile experimental model for the investigation of arterial thrombosis.
    Thrombosis research, 1992, Jul-01, Volume: 67, Issue:1

    Topics: Anastomosis, Surgical; Animals; Aspirin; Blood Coagulation Tests; Blood Vessel Prosthesis; Carotid A

1992
Aspirin reduces the growth of medial and neointimal thickenings in balloon-injured rat carotid arteries.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Animals; Aspirin; Carotid Arteries; Carotid Artery Diseases; Carotid Artery Injuries; Male; Rats; Ra

1990
Is vasospasm related to platelet deposition? Relationship in a porcine preparation of arterial injury in vivo.
    Circulation, 1987, Volume: 75, Issue:1

    Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Carotid Artery Diseases; Carotid Artery In

1987