aspirin has been researched along with Carotid Arteriopathies, Traumatic in 20 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This produced an occlusive thrombus in all vehicle-treated ferrets within 41 +/- 3 min with an average weight of 8 +/- 1 mg (n = 7)." | 5.29 | A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin. ( Durham, SK; Megill, JR; Schumacher, WA; Steinbacher, TE, 1996) |
| "The objective of this study was to determine if orally-administered PD0348292, a direct specific factor Xa inhibitor, inhibits thrombosis following porcine carotid arterial injury comparably to aspirin or clopidogrel alone or in combination." | 3.74 | Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. ( Baxi, S; Karnicki, K; Leadley, RJ; McBane, RD; Peterson, T; Wysokinski, W, 2008) |
| "Recurrent epistaxis is a rare presentation of internal carotid artery C4/C5 segment pseudo-aneurysm rupture." | 1.40 | Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report. ( Bazina, A; Hucika, Z; Mišmaš, A; Pavliša, G; Poljaković, Z, 2014) |
| "Blunt carotid artery injuries (BCI) are being recognized and treated with increasing frequency because of improved screening protocols." | 1.35 | Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm. ( Berne, JD; McGovern, TM; Norwood, SH; Reuland, KR; Rowe, SA; Villarreal, DH, 2008) |
| "Assessment of platelet-thrombus formation with this technique was more sensitive than change in flow in determining antithrombotic efficacy, and thrombus formation was detected earlier." | 1.31 | In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector. ( Badimon, JJ; Chesebro, JH; Fallon, JT; Fuster, V; Gallo, R; Helft, G; Osende, JI; Padurean, A; Rodriguez, OX; Worthley, SG; Zaman, AG, 2000) |
| "Thrombocytopenia was produced by a polyclonal antiplatelet serum that depleted circulating platelet count by 84% without influencing neutrophil count." | 1.30 | Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs. ( Guidoin, R; Latour, JG; Merhi, Y; Provost, P, 1997) |
| "Aspirin treatment in combination with neutropenia produced a 50% reduction in whole blood platelet aggregation, resulted in a significant inhibition of platelet deposition to deeply injured arteries, and decreased vasoconstriction by 66% to 15." | 1.29 | Neutrophil implications in platelet deposition and vasoconstriction after deep arterial injury by angioplasty in pigs. ( Lacoste, LL; Lam, JY; Merhi, Y, 1994) |
| "This produced an occlusive thrombus in all vehicle-treated ferrets within 41 +/- 3 min with an average weight of 8 +/- 1 mg (n = 7)." | 1.29 | A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin. ( Durham, SK; Megill, JR; Schumacher, WA; Steinbacher, TE, 1996) |
| "However, their effects on thrombus formation have rarely been evaluated in experimental animals in vivo." | 1.29 | In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis. ( Iwamoto, Y; Naritomi, H; Nishimura, H; Sugita, M; Tachibana, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Catapano, JS | 1 |
| Israr, S | 1 |
| Whiting, AC | 1 |
| Hussain, OM | 1 |
| Snyder, LA | 1 |
| Albuquerque, FC | 1 |
| Ducruet, AF | 1 |
| Nakaji, P | 1 |
| Lawton, MT | 1 |
| Weinberg, JA | 1 |
| Zabramski, JM | 1 |
| Poli, L | 1 |
| Mardighian, D | 1 |
| Gamba, M | 1 |
| Padovani, A | 1 |
| Pezzini, A | 1 |
| Bazina, A | 1 |
| Mišmaš, A | 1 |
| Hucika, Z | 1 |
| Pavliša, G | 1 |
| Poljaković, Z | 1 |
| Ishii, A | 1 |
| Viñuela, F | 1 |
| Murayama, Y | 1 |
| Yuki, I | 1 |
| Nien, YL | 1 |
| Yeh, DT | 1 |
| Vinters, HV | 1 |
| Berne, JD | 1 |
| Reuland, KR | 1 |
| Villarreal, DH | 1 |
| McGovern, TM | 1 |
| Rowe, SA | 1 |
| Norwood, SH | 1 |
| Karnicki, K | 1 |
| Leadley, RJ | 1 |
| Baxi, S | 1 |
| Peterson, T | 1 |
| Wysokinski, W | 1 |
| McBane, RD | 1 |
| Buchanan, MR | 1 |
| Dejana, E | 1 |
| Gent, M | 1 |
| Mustard, JF | 1 |
| Hirsch, J | 1 |
| Merhi, Y | 2 |
| Lacoste, LL | 1 |
| Lam, JY | 2 |
| Colella, JJ | 1 |
| Diamond, DL | 1 |
| Schumacher, WA | 1 |
| Steinbacher, TE | 1 |
| Megill, JR | 1 |
| Durham, SK | 1 |
| Nishimura, H | 1 |
| Naritomi, H | 1 |
| Iwamoto, Y | 1 |
| Tachibana, H | 1 |
| Sugita, M | 1 |
| Provost, P | 1 |
| Guidoin, R | 1 |
| Latour, JG | 1 |
| Hoffmann, P | 1 |
| Bernat, A | 1 |
| Savi, P | 1 |
| Herbert, JM | 1 |
| Zaman, AG | 1 |
| Osende, JI | 1 |
| Chesebro, JH | 2 |
| Fuster, V | 2 |
| Padurean, A | 1 |
| Gallo, R | 1 |
| Worthley, SG | 1 |
| Helft, G | 1 |
| Rodriguez, OX | 1 |
| Fallon, JT | 1 |
| Badimon, JJ | 1 |
| Ragni, M | 1 |
| Golino, P | 1 |
| Cirillo, P | 1 |
| Scognamiglio, A | 1 |
| Piro, O | 1 |
| Esposito, N | 1 |
| Battaglia, C | 1 |
| Botticella, F | 1 |
| Ponticelli, P | 1 |
| Ramunno, L | 1 |
| Chiariello, M | 1 |
| Prieto, AR | 1 |
| Ma, H | 1 |
| Huang, R | 1 |
| Khan, G | 1 |
| Schwartz, KA | 1 |
| Hage-Korban, EE | 1 |
| Schmaier, AH | 1 |
| Davis, JM | 1 |
| Hasan, AA | 1 |
| Abela, GS | 1 |
| Elliott, MA | 1 |
| Taylor, LP | 1 |
| Cooley, BC | 1 |
| Li, X | 1 |
| Dzwierzynski, W | 1 |
| Gruel, SM | 1 |
| Hall, RL | 1 |
| Wright, RR | 1 |
| O'Brien, EM | 1 |
| Fagan, D | 1 |
| Hanel, DP | 1 |
| Gould, JS | 1 |
| Völker, W | 1 |
| Faber, V | 1 |
| Steele, PM | 1 |
| Badimon, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot, Non-masked, Randomized Clinical Trial for Evaluation of Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).[NCT05868525] | Phase 4 | 98 participants (Anticipated) | Interventional | 2024-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 other studies available for aspirin and Carotid Arteriopathies, Traumatic
| Article | Year |
|---|---|
Management of Extracranial Blunt Cerebrovascular Injuries: Experience with an Aspirin-Based Approach.
Topics: Adolescent; Adult; Aged; Anticoagulants; Aortic Dissection; Aspirin; Carotid Artery Injuries; Caroti | 2020 |
Short-term outcome of carotid dissecting pseudoaneurysm: is it always benign?
Topics: Adult; Aortic Dissection; Aspirin; Brain; Carotid Artery Injuries; Clopidogrel; Endovascular Procedu | 2018 |
Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report.
Topics: Angiography, Digital Subtraction; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Clopid | 2014 |
Swine model of carotid artery atherosclerosis: experimental induction by surgical partial ligation and dietary hypercholesterolemia.
Topics: Angiography; Angioplasty, Balloon; Animals; Aspirin; Calcinosis; Carotid Arteries; Carotid Artery In | 2006 |
Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm.
Topics: Accidents, Traffic; Adolescent; Adult; Aneurysm, False; Aspirin; Carotid Artery Injuries; Carotid Ar | 2008 |
Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.
Topics: Administration, Oral; Animals; Aspirin; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; C | 2008 |
Enhanced platelet accumulation onto injured carotid arteries in rabbits after aspirin treatment.
Topics: Animals; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Carotid Artery Thrombo | 1981 |
Neutrophil implications in platelet deposition and vasoconstriction after deep arterial injury by angioplasty in pigs.
Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Carotid Artery Injuries; Neutropenia; Neut | 1994 |
Blunt carotid injury: reassessing the role of anticoagulation.
Topics: Adult; Anticoagulants; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Cerebral Angiogra | 1996 |
A ferret model of electrical-induction of arterial thrombosis that is sensitive to aspirin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Blood Platelet | 1996 |
In vivo evaluation of antiplatelet agents in gerbil model of carotid artery thrombosis.
Topics: Animals; Aspirin; Carotid Artery Diseases; Carotid Artery Injuries; Carotid Artery, Common; Cerebrov | 1996 |
Importance of platelets in neutrophil adhesion and vasoconstriction after deep carotid arterial injury by angioplasty in pigs.
Topics: Angioplasty, Balloon; Animals; Aspirin; Blood Platelets; Carotid Artery Injuries; Cell Adhesion; Mic | 1997 |
Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
Topics: Animals; Aspirin; Benzylamines; Bleeding Time; Carotid Artery Injuries; Collagen; Fibrinolytic Agent | 1998 |
In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anticoagulants; Aspirin; Blood Platelets; Ca | 2000 |
Endogenous tissue factor pathway inhibitor modulates thrombus formation in an in vivo model of rabbit carotid artery stenosis and endothelial injury.
Topics: Animals; Antibodies; Aspirin; Blood Coagulation; Blood Flow Velocity; Carotid Artery Injuries; Carot | 2000 |
Thrombostatin, a bradykinin metabolite, reduces platelet activation in a model of arterial wall injury.
Topics: Animals; Aspirin; Blood Platelets; Bradykinin; Carotid Arteries; Carotid Artery Injuries; Carotid St | 2002 |
"Shiatsu sympathectomy": ICA dissection associated with a shiatsu massager.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carotid Artery Injuries; Female; Headache; Humans; | 2002 |
The de-endothelialized rat carotid arterial graft: a versatile experimental model for the investigation of arterial thrombosis.
Topics: Anastomosis, Surgical; Animals; Aspirin; Blood Coagulation Tests; Blood Vessel Prosthesis; Carotid A | 1992 |
Aspirin reduces the growth of medial and neointimal thickenings in balloon-injured rat carotid arteries.
Topics: Animals; Aspirin; Carotid Arteries; Carotid Artery Diseases; Carotid Artery Injuries; Male; Rats; Ra | 1990 |
Is vasospasm related to platelet deposition? Relationship in a porcine preparation of arterial injury in vivo.
Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Carotid Artery Diseases; Carotid Artery In | 1987 |