aspirin has been researched along with Cardiomyopathy, Dilated in 27 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The evidence is uncertain if warfarin has any effect on all-cause death compared to placebo or no treatment, but it may increase the risk of major bleeding events." | 5.12 | Anticoagulation versus placebo for heart failure in sinus rhythm. ( Kozieł, M; Lip, GY; Shantsila, E, 2021) |
| "Although patients with chronic heart failure and left ventricular dilation have a higher risk of thromboembolism, data are insufficient to recommend warfarin or aspirin prophylaxis in the absence of additional indications for such therapy." | 4.81 | Anticoagulation in patients with dilated cardiomyopathy and sinus rhythm: a critical literature review. ( Geraci, SA; Miller, AB; Sirajuddin, RA, 2002) |
| "Myocardial infarction was assessed using the third universal definition." | 2.82 | Effectiveness of platelet inhibition on major adverse cardiac events in non-cardiac surgery after percutaneous coronary intervention: a prospective cohort study. ( Beattie, WS; Carroll, J; Grewal, D; Harsha, P; Karkouti, K; Ragoonanan, T; Starzyk, Ł; Syed, S; Travis, G; Wąsowicz, M; Wijeysundera, DN, 2016) |
| "Patients with Dilated Cardiomyopathy (DCM) were randomised to receive either warfarin or placebo." | 2.72 | Efficacy of antithrombotic therapy in chronic heart failure: the HELAS study. ( Cokkinos, DV; Haralabopoulos, GC; Kostis, JB; Toutouzas, PK, 2006) |
| "Patients with dilated cardiomyopathy have multiple factors that predispose to thromboembolic events." | 2.40 | Anticoagulation in dilated cardiomyopathy. ( Goldhaber, SZ; Koniaris, LS, 1998) |
| "None experienced strokes or transient ischemic attacks." | 1.35 | Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist device. ( Dia, M; Gallagher, C; Silver, MA; Slaughter, MS; Sobieski, MA, 2008) |
| "An unexpected delayed increase in dilated cardiomyopathy may be observed in countries affected by the outbreak of chikungunya virus disease during 2005-2007." | 1.35 | Chikungunya virus-induced myopericarditis: toward an increase of dilated cardiomyopathy in countries with epidemics? ( Oliver, M; Paule, P; Simon, F, 2008) |
| "Myocarditis and dilated cardiomyopathy is characterized by dilatation of all four cardiac chambers and decreased systolic function of the heart, especially in the left ventricle." | 1.34 | Treatment of massive cardiac thrombi in a patient with protein C and protein S deficiency. ( Cağdaş, DN; Paç, FA, 2007) |
| "Pump thrombus is a potentially serious complication with few available treatment options." | 1.33 | An alternative treatment strategy for pump thrombus in the DeBakey VAD Child: use of clopidogrel as a thrombolytic agent. ( Carberry, KE; Chang, AC; Dreyer, WJ; Kennedy, CE; McKenzie, ED; Moffett, BS; Morales, DL; Price, JF; Studer, MA; Teitel, ER, 2006) |
| "Their mitral regurgitation (MR) is a result of left ventricular (LV) geometrical distortion." | 1.33 | Flexible versus nonflexible mitral valve rings for congestive heart failure: differential durability of repair. ( Bolling, SF; Geltz, A; Spoor, MT, 2006) |
| "Diagnoses included dilated cardiomyopathy (n = 15), myocarditis (n = 2), and postcardiotomy ventricular failure (n = 1)." | 1.33 | Ventricular assist device support in children and adolescents as a bridge to heart transplantation. ( Buchanan, JR; Gandhi, SK; Kormos, RL; Morell, VO; Sharma, MS; Wearden, PD; Webber, SA, 2006) |
| "A 48-year-old patient with dilated cardiomyopathy complained of dyspnea at rest, severe sleeplessness and a slight pain in the stomach." | 1.31 | [Increased thrombocyte activation in dilated cardiomyopathy: a risk factor for development of ventricular thrombosis despite anticoagulant therapy?]. ( Hohmann, C; Jaster, M; Kühl, U; Pauschinger, M; Rauch, U; Schultheiss, HP; Schwimmbeck, PL; Weikert, U, 2002) |
| "Deferoxamine therapy was continued throughout 2 pregnancies, while in the other it was stopped after 8 weeks: no abnormalities were noted in the children." | 1.31 | High-risk pregnancy in beta-thalassemia major women. Report of three cases. ( De Marzi, CA; Magliari, F; Perniola, R; Rosatelli, MC, 2000) |
| "Left ventricular dysfunction was attributed to idiopathic dilated cardiomyopathy in 18 and coronary artery disease in 19 patients." | 1.30 | Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy. ( Atar, D; Gurbel, PA; Lowry, DR; Murugesan, SR; O'Connor, CM; Pothula, A; Serebruany, VL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 16 (59.26) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Shantsila, E | 2 |
| Kozieł, M | 1 |
| Lip, GY | 2 |
| Chen, K | 1 |
| Williams, S | 1 |
| Chan, AK | 1 |
| Mondal, TK | 1 |
| Dalén, M | 1 |
| Sartipy, U | 1 |
| Corbascio, M | 1 |
| Lund, LH | 1 |
| Grinnemo, KH | 1 |
| Wąsowicz, M | 1 |
| Syed, S | 1 |
| Wijeysundera, DN | 1 |
| Starzyk, Ł | 1 |
| Grewal, D | 1 |
| Ragoonanan, T | 1 |
| Harsha, P | 1 |
| Travis, G | 1 |
| Carroll, J | 1 |
| Karkouti, K | 1 |
| Beattie, WS | 1 |
| Dropiński, J | 1 |
| Szczeklik, W | 1 |
| Sokołowska, B | 1 |
| Celińska-Lowenhoff, M | 1 |
| Milewski, M | 1 |
| Szczeklik, A | 1 |
| Slaughter, MS | 1 |
| Sobieski, MA | 1 |
| Gallagher, C | 1 |
| Dia, M | 1 |
| Silver, MA | 1 |
| Catez, E | 1 |
| Ngoc, ET | 1 |
| Decoodt, P | 1 |
| Muñiz, AE | 1 |
| Weikert, U | 1 |
| Rauch, U | 1 |
| Kühl, U | 1 |
| Hohmann, C | 1 |
| Jaster, M | 1 |
| Pauschinger, M | 1 |
| Schwimmbeck, PL | 1 |
| Schultheiss, HP | 1 |
| Cleland, JG | 1 |
| Findlay, I | 1 |
| Jafri, S | 1 |
| Sutton, G | 1 |
| Falk, R | 1 |
| Bulpitt, C | 1 |
| Prentice, C | 1 |
| Ford, I | 1 |
| Trainer, A | 1 |
| Poole-Wilson, PA | 1 |
| Kohmoto, T | 1 |
| Oz, MC | 1 |
| Naka, Y | 1 |
| Higashikuni, Y | 1 |
| Sata, M | 1 |
| Nagai, R | 1 |
| Cokkinos, DV | 1 |
| Haralabopoulos, GC | 1 |
| Kostis, JB | 1 |
| Toutouzas, PK | 1 |
| Studer, MA | 1 |
| Kennedy, CE | 1 |
| Dreyer, WJ | 1 |
| Price, JF | 1 |
| Moffett, BS | 1 |
| Teitel, ER | 1 |
| Carberry, KE | 1 |
| Morales, DL | 1 |
| McKenzie, ED | 1 |
| Chang, AC | 1 |
| Spoor, MT | 1 |
| Geltz, A | 1 |
| Bolling, SF | 1 |
| Sharma, MS | 1 |
| Webber, SA | 1 |
| Morell, VO | 1 |
| Gandhi, SK | 1 |
| Wearden, PD | 1 |
| Buchanan, JR | 1 |
| Kormos, RL | 1 |
| Paç, FA | 1 |
| Cağdaş, DN | 1 |
| Simon, F | 1 |
| Paule, P | 1 |
| Oliver, M | 1 |
| Ricou, FJ | 1 |
| Arroyo, JF | 1 |
| Guazzi, M | 1 |
| Melzi, G | 1 |
| Agostoni, P | 1 |
| Koniaris, LS | 1 |
| Goldhaber, SZ | 1 |
| Perniola, R | 1 |
| Magliari, F | 1 |
| Rosatelli, MC | 1 |
| De Marzi, CA | 1 |
| Serebruany, VL | 1 |
| Murugesan, SR | 1 |
| Pothula, A | 1 |
| Atar, D | 1 |
| Lowry, DR | 1 |
| O'Connor, CM | 1 |
| Gurbel, PA | 1 |
| Adachi, H | 1 |
| Sakurai, S | 1 |
| Tanehata, M | 1 |
| Oshima, S | 1 |
| Taniguchi, K | 1 |
| Sirajuddin, RA | 1 |
| Miller, AB | 1 |
| Geraci, SA | 1 |
| Arslan, Z | 1 |
| Tezic, T | 1 |
| Akinci, A | 1 |
| Gur, I | 1 |
| Haspolat, E | 1 |
| Karademir, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Association Between Platelet Inhibition and Perioperative Major Adverse Cardiac Events In Post-Percutaneous Coronary Intervention (PCI) Patients Undergoing Non-Cardiac Surgery[NCT01707459] | 201 participants (Actual) | Observational | 2010-03-31 | Completed | |||
| Effects of APIXaban on BRAIN Protection in Patients With Sinus Rhythm and Heart Failure: APIXBRAIN-HF Trial[NCT04696120] | Phase 2 | 200 participants (Anticipated) | Interventional | 2021-03-02 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for aspirin and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Anticoagulation versus placebo for heart failure in sinus rhythm.
Topics: Administration, Oral; Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Chronic Disease; Heart Failu | 2021 |
Thrombosis and embolism in pediatric cardiomyopathy.
Topics: Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Cardiomyopathy, Restrictive; Child; Disease Manage | 2013 |
Anticoagulation versus placebo for heart failure in sinus rhythm.
Topics: Administration, Oral; Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Chronic Disease; Heart Failu | 2014 |
Late bleeding from right internal mammary artery after HeartMate left ventricular assist device implantation.
Topics: Adult; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cardiomyopathy, Dila | 2004 |
[Diagnosis and treatment of cerebrovascular accidents of cardioembolic origin].
Topics: Aged; Anticoagulants; Aortic Diseases; Arteriosclerosis; Aspirin; Atrial Fibrillation; Cardiomyopath | 1996 |
Anticoagulation in dilated cardiomyopathy.
Topics: Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Heart Failure; Humans; Risk Factors; Thromboemboli | 1998 |
Anticoagulation in patients with dilated cardiomyopathy and sinus rhythm: a critical literature review.
Topics: Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Heart Failure; Humans; Incidence; Thromboembolism; | 2002 |
4 trials available for aspirin and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Effectiveness of platelet inhibition on major adverse cardiac events in non-cardiac surgery after percutaneous coronary intervention: a prospective cohort study.
Topics: Aged; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Cohort Studies; Female; Heart Diseases; Humans; | 2016 |
The Warfarin/Aspirin Study in Heart failure (WASH): a randomized trial comparing antithrombotic strategies for patients with heart failure.
Topics: Aged; Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Feasibility Studies; Female; Hospitalization | 2004 |
Efficacy of antithrombotic therapy in chronic heart failure: the HELAS study.
Topics: Aged; Anticoagulants; Antithrombins; Aspirin; Cardiac Output, Low; Cardiomyopathy, Dilated; Double-B | 2006 |
Comparison of changes in respiratory function and exercise oxygen uptake with losartan versus enalapril in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Cardiomyopathy, Dilated; | 1997 |
16 other studies available for aspirin and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
HeartWare left ventricular assist device thrombosis in aspirin non-responder.
Topics: Aged; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Drug Resistance; Drug Substitution; Fibrinolyti | 2014 |
[Congestive cardiomyopathy and left intraventricular thrombus as a manifestation of Churg-Strauss syndrome].
Topics: Adult; Aspirin; Cardiomyopathy, Dilated; Churg-Strauss Syndrome; Female; Heart Diseases; Heparin, Lo | 2008 |
Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist device.
Topics: Adult; Aged; Aspirin; Brain Diseases, Metabolic; Cardiomyopathy, Dilated; Cause of Death; Cognition | 2008 |
Fulminant hepatic necrosis resulting from heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiomyopathy, Dilated; Coma; Diagnosis, Differe | 2009 |
Thrombolytic therapy for acute stroke in a teenager.
Topics: Adolescent; Aspirin; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cerebral Angiography; Defibril | 2012 |
[Increased thrombocyte activation in dilated cardiomyopathy: a risk factor for development of ventricular thrombosis despite anticoagulant therapy?].
Topics: Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Cardiovascular Agents; Drug Therapy, Combination; | 2002 |
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
Topics: Aged; Aspirin; Benzimidazoles; Biphenyl Compounds; Cardiomyopathy, Dilated; Chest Pain; Drug Therapy | 2005 |
An alternative treatment strategy for pump thrombus in the DeBakey VAD Child: use of clopidogrel as a thrombolytic agent.
Topics: Adolescent; Aspirin; Cardiomyopathy, Dilated; Clopidogrel; Equipment Failure; Fibrinolytic Agents; H | 2006 |
Flexible versus nonflexible mitral valve rings for congestive heart failure: differential durability of repair.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiomyopathy, Dilated; Combined Modality | 2006 |
Ventricular assist device support in children and adolescents as a bridge to heart transplantation.
Topics: Adolescent; Anticoagulants; Aprotinin; Aspirin; Cardiomyopathy, Dilated; Child; Child, Preschool; Da | 2006 |
Treatment of massive cardiac thrombi in a patient with protein C and protein S deficiency.
Topics: Anticoagulants; Aspirin; Cardiomyopathy, Dilated; Child, Preschool; Female; Fibrinolytic Agents; Hea | 2007 |
Chikungunya virus-induced myopericarditis: toward an increase of dilated cardiomyopathy in countries with epidemics?
Topics: Adult; Alphavirus Infections; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Viral; Aspirin; C | 2008 |
High-risk pregnancy in beta-thalassemia major women. Report of three cases.
Topics: Adult; Aspirin; beta-Thalassemia; Cardiomyopathy, Dilated; Deferoxamine; Female; Humans; Pregnancy; | 2000 |
Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.
Topics: Aged; Aspirin; Biomarkers; Cardiomyopathy, Dilated; Coronary Disease; Enzyme-Linked Immunosorbent As | 1999 |
Effect of long-term exercise training on blood viscosity during endurance exercise at an anaerobic threshold intensity.
Topics: Adult; Aged; Anaerobic Threshold; Anticoagulants; Aspirin; Blood Viscosity; Cardiomyopathy, Dilated; | 2000 |
Dilated cardiomyopathy with recurrent intraventricular thrombosis.
Topics: Aspirin; Cardiomyopathy, Dilated; Coronary Thrombosis; Echocardiography; Electrocardiography; Heart | 1992 |