aspirin has been researched along with Cardiomegaly in 15 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite its well-known antithrombotic properties, the effect of aspirin on blood pressure (BP) and hypertension pathology is unclear." | 7.91 | Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat. ( Andrews, KL; Chin-Dusting, JPF; Dragoljevic, D; Gaspari, T; Jefferis, AM; Jennings, GL; Khan, SI; Lee, MKS; Moore, XL; Murphy, AJ; Shihata, WA; Vinh, A, 2019) |
| "Rofecoxib also reduced cardiac hypertrophy." | 5.33 | Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005) |
| "Treatment with Verapamil or aspirin reduced both chronic hypoxic pulmonary hypertension and the hypertrophy of the right ventricle." | 5.26 | Effects of verapamil and aspirin on experimental chronic hypoxic pulmonary hypertension and right ventricular hypertrophy in rats. ( Kentera, D; Susić, D; Zdravković, M, 1979) |
| "We analyzed the use of aspirin before and after myocardial infarction and that of calcium antagonists after myocardial infarction in 2231 survivors of myocardial infarction enrolled in the Survival and Ventricular Enlargement (SAVE) study over a three-year period (from January 1987 through January 1990)." | 5.07 | Do the results of randomized clinical trials of cardiovascular drugs influence medical practice? The SAVE Investigators. ( Braunwald, E; Hamm, P; Lamas, GA; Pfeffer, MA; Rouleau, JL; Wertheimer, J, 1992) |
| "Despite its well-known antithrombotic properties, the effect of aspirin on blood pressure (BP) and hypertension pathology is unclear." | 3.91 | Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat. ( Andrews, KL; Chin-Dusting, JPF; Dragoljevic, D; Gaspari, T; Jefferis, AM; Jennings, GL; Khan, SI; Lee, MKS; Moore, XL; Murphy, AJ; Shihata, WA; Vinh, A, 2019) |
| "Rofecoxib also reduced cardiac hypertrophy." | 1.33 | Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005) |
| "Treatment with Verapamil or aspirin reduced both chronic hypoxic pulmonary hypertension and the hypertrophy of the right ventricle." | 1.26 | Effects of verapamil and aspirin on experimental chronic hypoxic pulmonary hypertension and right ventricular hypertrophy in rats. ( Kentera, D; Susić, D; Zdravković, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, SI | 1 |
| Shihata, WA | 1 |
| Andrews, KL | 1 |
| Lee, MKS | 1 |
| Moore, XL | 1 |
| Jefferis, AM | 1 |
| Vinh, A | 1 |
| Gaspari, T | 1 |
| Dragoljevic, D | 1 |
| Jennings, GL | 1 |
| Murphy, AJ | 1 |
| Chin-Dusting, JPF | 1 |
| Doğan, M | 1 |
| Akdemir, R | 1 |
| Biçer Yeşilay, A | 1 |
| Kılıç, H | 1 |
| Karakurt, O | 1 |
| Balcı, MM | 1 |
| Orçan, S | 1 |
| Wu, R | 2 |
| Yin, D | 1 |
| Sadekova, N | 1 |
| Deschepper, CF | 1 |
| de Champlain, J | 2 |
| Girouard, H | 1 |
| Laplante, MA | 1 |
| Planavila, A | 1 |
| Rodríguez-Calvo, R | 1 |
| de Arriba, AF | 1 |
| Sánchez, RM | 1 |
| Laguna, JC | 1 |
| Merlos, M | 1 |
| Vazquez-Carrera, M | 1 |
| Yoo, WH | 1 |
| DePace, NL | 1 |
| Burke, W | 1 |
| Kotler, MN | 1 |
| Glazier, EE | 1 |
| Gavaghan, BJ | 1 |
| Kittleson, MD | 1 |
| McAloose, D | 1 |
| Kentera, D | 1 |
| Susić, D | 1 |
| Zdravković, M | 1 |
| Salazar Mena, J | 1 |
| García Moya, JB | 1 |
| Felipe Villaverde, J | 1 |
| García de la Calzada, MD | 1 |
| Gunby, P | 1 |
| Lamas, GA | 1 |
| Pfeffer, MA | 1 |
| Hamm, P | 1 |
| Wertheimer, J | 1 |
| Rouleau, JL | 1 |
| Braunwald, E | 1 |
| Momma, K | 1 |
| Takao, A | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Miller, GC | 1 |
| Witham, AC | 1 |
1 review available for aspirin and Cardiomegaly
| Article | Year |
|---|---|
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
1 trial available for aspirin and Cardiomegaly
| Article | Year |
|---|---|
Do the results of randomized clinical trials of cardiovascular drugs influence medical practice? The SAVE Investigators.
Topics: Adult; Aged; Aspirin; Calcium Channel Blockers; Captopril; Cardiomegaly; Cardiovascular Agents; Dilt | 1992 |
13 other studies available for aspirin and Cardiomegaly
| Article | Year |
|---|---|
Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat.
Topics: Adaptive Immunity; Angiotensin II; Animals; Aspirin; Biomarkers; Blood Pressure; Blood Vessels; Card | 2019 |
Calcified ball-like left ventricular thrombus embolized during echocardiography follow-up.
Topics: Aspirin; Atrial Fibrillation; Cardiomegaly; Dyspnea; Echocardiography; Embolization, Therapeutic; He | 2010 |
Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters.
Topics: Animals; Aorta; Aspirin; Blood Pressure; Body Weight; Cardiomegaly; Cardiomyopathies; Cardiotonic Ag | 2012 |
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cult | 2005 |
Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite.
Topics: Animals; Aspirin; Base Sequence; Cardiomegaly; DNA Primers; Electrophoretic Mobility Shift Assay; Im | 2006 |
Adult onset Still's disease flared with pericardial effusion.
Topics: Adrenal Cortex Hormones; Aspirin; Cardiomegaly; Follow-Up Studies; Humans; Immunosuppressive Agents; | 2008 |
An unusual case of Bjork-Shiley mitral valve dysfunction corrected nonsurgically.
Topics: Aspirin; Cardiomegaly; Dipyridamole; Echocardiography; Female; Furosemide; Heart Murmurs; Heart Valv | 1981 |
Persistent atrial standstill in a cat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arrhythmias, Cardiac; Asp | 1999 |
Effects of verapamil and aspirin on experimental chronic hypoxic pulmonary hypertension and right ventricular hypertrophy in rats.
Topics: Animals; Aspirin; Biological Transport; Calcium; Cardiomegaly; Chronic Disease; Female; Haplorhini; | 1979 |
[Acute rheumatic carditis. Follow-up (author's transl)].
Topics: Acute Disease; Adrenal Cortex Hormones; Aspirin; Cardiomegaly; Child; Child, Preschool; Endocarditis | 1979 |
Forum offers hints of future therapy, prevention programs for combating cardiovascular problems.
Topics: Animals; Arteriosclerosis; Aspirin; Cardiomegaly; Cardiovascular Diseases; Female; Genetic Therapy; | 1992 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arterios | 1990 |
Delayed febrile pleuropericarditis after sepsis. A possible analogue of the postcardiotomy syndrome.
Topics: Adult; Aspirin; Blood Sedimentation; Cardiomegaly; Erythrocytes; Female; Fever; Heart Auscultation; | 1973 |