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aspirin and Carcinoma, Small Cell

aspirin has been researched along with Carcinoma, Small Cell in 8 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)

Research Excerpts

ExcerptRelevanceReference
"A patient who had small cell lung cancer complicated by symmetrical peripheral gangrene, secondary to spontaneous platelet aggregation, improved dramatically after starting aspirin treatment."7.68Digital gangrene in small cell lung cancer: response to aspirin treatment. ( Arrowsmith, JE; Bevan, DH; Cummin, AR; Nanson, EM; Woodhead, MA, 1991)
"A patient who had small cell lung cancer complicated by symmetrical peripheral gangrene, secondary to spontaneous platelet aggregation, improved dramatically after starting aspirin treatment."3.68Digital gangrene in small cell lung cancer: response to aspirin treatment. ( Arrowsmith, JE; Bevan, DH; Cummin, AR; Nanson, EM; Woodhead, MA, 1991)
"To complete research in this type of coagulation and cancer, a multicentric randomized clinical trial was performed, including 303 patients with small cell lung cancer (SCLC), treated by the addition of aspirin at 1 g/day (a dosage at which aspirin is considered to be a platelet aggregation inhibitor) to combined chemotherapy."2.67No effect of an antiaggregant treatment with aspirin in small cell lung cancer treated with CCAVP16 chemotherapy. Results from a randomized clinical trial of 303 patients. The "Petites Cellules" Group. ( Chastang, C; Fabre, C; Lebeau, B; Massin, F; Muir, JF; Vincent, J, 1993)
"Risk of lung cancer was a non-significant 16% lower for regular aspirin users of one or two tablets per week and a significant 55% higher for users of 15 or more tablets per week compared with women who never regularly used aspirin."2.44Aspirin and lung cancer risk in a cohort study of women: dosage, duration and latency. ( Bain, C; Chan, AT; Colditz, GA; Feskanich, D; Pandeya, N; Speizer, FE, 2007)
" Although there was no clear evidence of a dose-response relationship, we observed risk reductions associated with greater frequency of use."1.31Regular aspirin use and lung cancer risk. ( Bepler, G; Cummings, KM; Falkner, KL; Loewen, GM; Menezes, RJ; Moysich, KB; Reid, ME; Ronsani, A; Swede, H, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OchmaƄski, W1
Moysich, KB1
Menezes, RJ1
Ronsani, A1
Swede, H1
Reid, ME1
Cummings, KM1
Falkner, KL1
Loewen, GM1
Bepler, G1
Feskanich, D1
Bain, C1
Chan, AT1
Pandeya, N1
Speizer, FE1
Colditz, GA1
Lebeau, B2
Chastang, C1
Muir, JF1
Vincent, J1
Massin, F1
Fabre, C1
Akhmedkhanov, A1
Toniolo, P1
Zeleniuch-Jacquotte, A1
Koenig, KL1
Shore, RE1
Arrowsmith, JE1
Woodhead, MA1
Bevan, DH1
Nanson, EM1
Cummin, AR1
Lau, SS1
McMahon, JB1
McMenamin, MG1
Schuller, HM1
Boyd, MR1

Reviews

1 review available for aspirin and Carcinoma, Small Cell

ArticleYear
Aspirin and lung cancer risk in a cohort study of women: dosage, duration and latency.
    British journal of cancer, 2007, Nov-05, Volume: 97, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca

2007

Trials

3 trials available for aspirin and Carcinoma, Small Cell

ArticleYear
[Influence of antiplatelet drugs (AD) on the efectiveness of combined therapy in patients with small cell lung cancer. Part I. Influence of AD on the haemostatic system].
    Przeglad lekarski, 2008, Volume: 65, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Blood Coagulation; Carcinoma,

2008
No effect of an antiaggregant treatment with aspirin in small cell lung cancer treated with CCAVP16 chemotherapy. Results from a randomized clinical trial of 303 patients. The "Petites Cellules" Group.
    Cancer, 1993, Mar-01, Volume: 71, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Small Cell; Cycloph

1993
[Global approach to the treatment of small cell bronchial cancers].
    Bulletin du cancer, 1987, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma,

1987

Other Studies

4 other studies available for aspirin and Carcinoma, Small Cell

ArticleYear
Regular aspirin use and lung cancer risk.
    BMC cancer, 2002, Nov-26, Volume: 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small C

2002
Aspirin and lung cancer in women.
    British journal of cancer, 2002, Jul-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Non-Small-Cell Lung; Carci

2002
Digital gangrene in small cell lung cancer: response to aspirin treatment.
    Thorax, 1991, Volume: 46, Issue:1

    Topics: Aspirin; Blood Platelet Disorders; Carcinoma, Small Cell; Fingers; Gangrene; Humans; Lung Neoplasms;

1991
Metabolism of arachidonic acid in human lung cancer cell lines.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Carci

1987