aspirin has been researched along with Carcinoma, Pancreatic Ductal in 10 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Carcinoma, Pancreatic Ductal: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current available therapies for pancreatic ductal adenocarcinoma (PDAC) provide minimal overall survival benefits and cause severe adverse effects." | 5.62 | Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity. ( Amin, S; K Pandey, M; Karelia, DN; Kim, S; Lu, J; Plano, D; Sharma, AK, 2021) |
| "Current available therapies for pancreatic ductal adenocarcinoma (PDAC) provide minimal overall survival benefits and cause severe adverse effects." | 1.62 | Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity. ( Amin, S; K Pandey, M; Karelia, DN; Kim, S; Lu, J; Plano, D; Sharma, AK, 2021) |
| "Furthermore, development of invasive pancreatic cancer in LsL-Kras(G12D); LsL-Trp53(R172H); Pdx1-Cre transgenic mice was partially inhibited by enalapril and aspirin." | 1.36 | The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer. ( Bartsch, DK; Buchholz, M; Chen, NM; Feldmann, G; Fendrich, V; Maitra, A; Neef, M; Slater, EP; Waldmann, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bassani-Sternberg, M | 1 |
| Digklia, A | 1 |
| Huber, F | 1 |
| Wagner, D | 1 |
| Sempoux, C | 1 |
| Stevenson, BJ | 1 |
| Thierry, AC | 1 |
| Michaux, J | 1 |
| Pak, H | 1 |
| Racle, J | 1 |
| Boudousquie, C | 1 |
| Balint, K | 1 |
| Coukos, G | 1 |
| Gfeller, D | 1 |
| Martin Lluesma, S | 1 |
| Harari, A | 1 |
| Demartines, N | 1 |
| Kandalaft, LE | 1 |
| Choi, JH | 1 |
| Lee, SH | 1 |
| Huh, G | 1 |
| Chun, JW | 1 |
| You, MS | 1 |
| Paik, WH | 1 |
| Ryu, JK | 1 |
| Kim, YT | 1 |
| Karelia, DN | 1 |
| Kim, S | 1 |
| K Pandey, M | 1 |
| Plano, D | 1 |
| Amin, S | 1 |
| Lu, J | 1 |
| Sharma, AK | 1 |
| Mensah, ET | 1 |
| Smyrk, T | 1 |
| Zhang, L | 1 |
| Bick, B | 1 |
| Wood-Wentz, CM | 1 |
| Buttar, N | 1 |
| Chari, ST | 1 |
| Gleeson, FC | 1 |
| Kendrick, M | 1 |
| Levy, M | 1 |
| Pearson, R | 1 |
| Petersen, BT | 1 |
| Vege, S | 1 |
| Enders, F | 1 |
| Limburg, P | 1 |
| Topazian, M | 1 |
| Plassmeier, L | 1 |
| Knoop, R | 1 |
| Waldmann, J | 2 |
| Kesselring, R | 1 |
| Buchholz, M | 2 |
| Fichtner-Feigl, S | 1 |
| Bartsch, DK | 2 |
| Fendrich, V | 2 |
| McAllister, F | 1 |
| Leach, SD | 1 |
| Zhang, Y | 1 |
| Liu, L | 1 |
| Fan, P | 1 |
| Bauer, N | 1 |
| Gladkich, J | 1 |
| Ryschich, E | 1 |
| Bazhin, AV | 1 |
| Giese, NA | 1 |
| Strobel, O | 1 |
| Hackert, T | 1 |
| Hinz, U | 1 |
| Gross, W | 1 |
| Fortunato, F | 1 |
| Herr, I | 1 |
| Chen, NM | 1 |
| Neef, M | 1 |
| Feldmann, G | 1 |
| Slater, EP | 1 |
| Maitra, A | 1 |
| Tan, XL | 1 |
| Reid Lombardo, KM | 1 |
| Bamlet, WR | 1 |
| Oberg, AL | 1 |
| Robinson, DP | 1 |
| Anderson, KE | 1 |
| Petersen, GM | 1 |
| Rao, CV | 1 |
| Mohammed, A | 1 |
| Janakiram, NB | 1 |
| Li, Q | 1 |
| Ritchie, RL | 1 |
| Lightfoot, S | 1 |
| Vibhudutta, A | 1 |
| Steele, VE | 1 |
1 trial available for aspirin and Carcinoma, Pancreatic Ductal
| Article | Year |
|---|---|
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patie
Topics: Amino Acid Sequence; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Aspirin; Carcinoma, P | 2019 |
9 other studies available for aspirin and Carcinoma, Pancreatic Ductal
| Article | Year |
|---|---|
The association between use of statin or aspirin and pancreatic ductal adenocarcinoma: A nested case-control study in a Korean nationwide cohort.
Topics: Adult; Aged; Aspirin; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Humans; Hydroxymet | 2019 |
Novel Seleno-Aspirinyl Compound AS-10 Induces Apoptosis, G1 Arrest of Pancreatic Ductal Adenocarcinoma Cells, Inhibits Their NF-κB Signaling, and Synergizes with Gemcitabine Cytotoxicity.
Topics: Acetylcysteine; Adenocarcinoma; Apoptosis; Aspirin; Carcinoma, Pancreatic Ductal; Caspases; Cell Lin | 2021 |
Cyclooxygenase-2 and Cytosolic Phospholipase A2 Are Overexpressed in Mucinous Pancreatic Cysts.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carcinoma, Pancreatic Ductal; Cyclooxygenase 2; Cyclooxygen | 2019 |
Aspirin prolongs survival and reduces the number of Foxp3+ regulatory T cells in a genetically engineered mouse model of pancreatic cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Aspirin; Carcinoma, Pancreatic Ductal; Cyclooxygenase Inhi | 2013 |
Targeting IL-17 for pancreatic cancer prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Aspirin; Carcinoma, Pancreatic Duct | 2014 |
Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Biomarkers, Tumor; Carcinoma, Panc | 2015 |
The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer.
Topics: Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticarcinogenic Agents; Aspirin; Carci | 2010 |
Aspirin, nonsteroidal anti-inflammatory drugs, acetaminophen, and pancreatic cancer risk: a clinic-based case-control study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Car | 2011 |
Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
Topics: Animals; Anticarcinogenic Agents; Aspirin; beta Catenin; Body Weight; Carcinoma in Situ; Carcinoma, | 2012 |