aspirin has been researched along with Carcinoma, Non-Small Cell Lung in 23 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured serum levels of soluble (s) P-selectin and thromboxane B2 (TxB2) in patients with lung cancer treated with gefitinib, and investigated the effect of low-dose aspirin on some adverse effects of gefitinib." | 2.72 | Aspirin reduces adverse effects of gefitinib. ( Kanazawa, S; Kinoshita, Y; Komiyama, Y; Muramatsu, M; Nomura, S; Yamaguchi, K, 2006) |
| "Combination therapy has become the hallmark of lung cancer treatment, as it reduces the dosage intensity of individual drugs while increasing their efficacy." | 1.72 | The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer. ( Li, N; Song, B; Xu, M; Yang, X, 2022) |
| "Aspirin has been reported to promote apoptosis, inhibit proliferation, stemness, angiogenesis, cancer-associated inflammation and migration in NSCLC." | 1.72 | Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation. ( Li, G; Ma, Y; Ren, G; Wang, X; Zheng, Z, 2022) |
| "Aspirin exposure was analyzed to identify a possible association with mortality in patients with inoperable NSCLC." | 1.62 | The association of aspirin use with overall survival of patients with inoperable non-small cell lung cancer: a retrospective study. ( Chen, PC; Chuang, MC; Hsieh, MJ; Hung, MS; Lin, YC; Yang, TM; Yang, YH, 2021) |
| "Aspirin has been shown to decrease cancer incidence and improve outcomes in various malignancies." | 1.56 | Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer. ( Fang, B; He, Y; Heymach, JV; Hong, L; Hubert, SM; Jack Lee, J; Le, X; Lewis, J; Liu, X; Nilsson, M; Rinsurongkawong, W; Roth, J; Spelman, A; Swisher, S; Wu, S; Zhang, J, 2020) |
| "The study aimed to investigate the effect and mechanism of aspirin combined with vinorelbine on the proliferation and apoptosis of non-small cell lung cancer cells." | 1.56 | [Effect and mechanism of aspirin combined with vinorelbine on non-small cell lung cancer]. ( Cui, L; Liu, Z; Qiu, YN; Teng, YO; Xu, Y; Yu, P, 2020) |
| "Aspirin has been proven to reduce cardiovascular mortality as a secondary prophylactic agent, but not as a primary agent." | 1.36 | Aspirin and non-small cell lung cancer resections: effect on long-term survival. ( Carr, M; Fontaine, E; McShane, J; Mediratta, N; Page, R; Poullis, M; Shackcloth, M; Soorae, A, 2010) |
| "Baby aspirin and NSAID use was associated with a significant reduction in risk of NSCLC only among 65- to 74-year-olds." | 1.35 | Regular adult aspirin use decreases the risk of non-small cell lung cancer among women. ( Claeys, GB; Cote, ML; Prysak, G; Schwartz, AG; Van Dyke, AL; Wenzlaff, AS, 2008) |
| " Although there was no clear evidence of a dose-response relationship, we observed risk reductions associated with greater frequency of use." | 1.31 | Regular aspirin use and lung cancer risk. ( Bepler, G; Cummings, KM; Falkner, KL; Loewen, GM; Menezes, RJ; Moysich, KB; Reid, ME; Ronsani, A; Swede, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 7 (30.43) | 2.80 |
| Authors | Studies |
|---|---|
| Basudhar, D | 1 |
| Bharadwaj, G | 1 |
| Cheng, RY | 1 |
| Jain, S | 1 |
| Shi, S | 1 |
| Heinecke, JL | 1 |
| Holland, RJ | 1 |
| Ridnour, LA | 1 |
| Caceres, VM | 1 |
| Spadari-Bratfisch, RC | 1 |
| Paolocci, N | 1 |
| Velázquez-Martínez, CA | 1 |
| Wink, DA | 1 |
| Miranda, KM | 1 |
| Chuang, MC | 1 |
| Yang, YH | 1 |
| Hsieh, MJ | 1 |
| Lin, YC | 1 |
| Yang, TM | 1 |
| Chen, PC | 1 |
| Hung, MS | 1 |
| Xu, M | 1 |
| Song, B | 1 |
| Yang, X | 1 |
| Li, N | 1 |
| Ren, G | 1 |
| Ma, Y | 1 |
| Wang, X | 1 |
| Zheng, Z | 1 |
| Li, G | 1 |
| Khan, P | 2 |
| Bhattacharya, A | 1 |
| Sengupta, D | 1 |
| Banerjee, S | 1 |
| Adhikary, A | 1 |
| Das, T | 2 |
| Han, R | 1 |
| Hao, S | 1 |
| Lu, C | 1 |
| Zhang, C | 1 |
| Lin, C | 1 |
| Li, L | 1 |
| Wang, Y | 1 |
| Hu, C | 1 |
| He, Y | 2 |
| Chen, J | 2 |
| Xia, J | 2 |
| Huang, J | 2 |
| Xu, R | 2 |
| Liu, X | 1 |
| Hong, L | 1 |
| Nilsson, M | 1 |
| Hubert, SM | 1 |
| Wu, S | 1 |
| Rinsurongkawong, W | 1 |
| Lewis, J | 1 |
| Spelman, A | 1 |
| Roth, J | 1 |
| Swisher, S | 1 |
| Jack Lee, J | 1 |
| Fang, B | 1 |
| Heymach, JV | 1 |
| Zhang, J | 1 |
| Le, X | 1 |
| Cui, L | 1 |
| Qiu, YN | 1 |
| Xu, Y | 1 |
| Teng, YO | 1 |
| Yu, P | 1 |
| Liu, Z | 1 |
| Ma, R | 1 |
| Bi, Y | 1 |
| Kou, J | 1 |
| Zhou, J | 1 |
| Shi, J | 1 |
| Song, JM | 1 |
| Upadhyaya, P | 1 |
| Kassie, F | 1 |
| Erickson, P | 1 |
| Gardner, LD | 1 |
| Loffredo, CA | 1 |
| St George, DM | 1 |
| Bowman, ED | 1 |
| Deepak, J | 1 |
| Mitchell, K | 1 |
| Meaney, CL | 1 |
| Langenberg, P | 1 |
| Bernat, DH | 1 |
| Amr, S | 1 |
| Ryan, BM | 1 |
| Mormile, R | 1 |
| Su, B | 1 |
| Wang, S | 1 |
| Jiang, HY | 1 |
| Huang, TB | 1 |
| Xu, L | 1 |
| Yu, J | 1 |
| Wu, Y | 1 |
| Geng, J | 1 |
| Yao, XD | 1 |
| Manna, A | 1 |
| Saha, S | 1 |
| Mohanty, S | 1 |
| Mukherjee, S | 1 |
| Mazumdar, M | 1 |
| Guha, D | 1 |
| Veeraputhiran, M | 1 |
| Sundermeyer, M | 1 |
| Fontaine, E | 1 |
| McShane, J | 1 |
| Page, R | 1 |
| Shackcloth, M | 1 |
| Mediratta, N | 1 |
| Carr, M | 1 |
| Soorae, A | 1 |
| Poullis, M | 1 |
| Chiaviello, A | 1 |
| Paciello, I | 1 |
| Postiglione, I | 1 |
| Crescenzi, E | 1 |
| Palumbo, G | 1 |
| Moysich, KB | 1 |
| Menezes, RJ | 1 |
| Ronsani, A | 1 |
| Swede, H | 1 |
| Reid, ME | 1 |
| Cummings, KM | 1 |
| Falkner, KL | 1 |
| Loewen, GM | 1 |
| Bepler, G | 1 |
| Kanazawa, S | 1 |
| Yamaguchi, K | 1 |
| Kinoshita, Y | 1 |
| Muramatsu, M | 1 |
| Komiyama, Y | 1 |
| Nomura, S | 1 |
| Van Dyke, AL | 1 |
| Cote, ML | 1 |
| Prysak, G | 1 |
| Claeys, GB | 1 |
| Wenzlaff, AS | 1 |
| Schwartz, AG | 1 |
| Akhmedkhanov, A | 1 |
| Toniolo, P | 1 |
| Zeleniuch-Jacquotte, A | 1 |
| Koenig, KL | 1 |
| Shore, RE | 1 |
1 review available for aspirin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Aspirin use and lung cancer risk: a possible relationship? Evidence from an updated meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Carcinoma, Non-Small-Cell | 2015 |
1 trial available for aspirin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Aspirin reduces adverse effects of gefitinib.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspi | 2006 |
21 other studies available for aspirin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azo Compounds; Carcinoma, Non-Small-Cell | 2013 |
The association of aspirin use with overall survival of patients with inoperable non-small cell lung cancer: a retrospective study.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinom | 2021 |
The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer.
Topics: Aspirin; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Prolife | 2022 |
Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation.
Topics: AMP-Activated Protein Kinases; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Glycolys | 2022 |
Aspirin enhances cisplatin sensitivity of resistant non-small cell lung carcinoma stem-like cells by targeting mTOR-Akt axis to repress migration.
Topics: Antineoplastic Agents; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cel | 2019 |
Aspirin sensitizes osimertinib-resistant NSCLC cells in vitro and in vivo via Bim-dependent apoptosis induction.
Topics: Acrylamides; Adult; Aged; Aged, 80 and over; Aniline Compounds; Animals; Apoptosis; Aspirin; Bcl-2-L | 2020 |
Effect of aspirin on PET parameters in primary non-small cell lung cancer and its relationship with prognosis.
Topics: Adult; Aged; Aspirin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Fluorodeoxygluc | 2020 |
Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer.
Topics: Acrylamides; Aniline Compounds; Aspirin; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lun | 2020 |
[Effect and mechanism of aspirin combined with vinorelbine on non-small cell lung cancer].
Topics: Apoptosis; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lu | 2020 |
Enhanced procoagulant activity of platelets after chemotherapy in non-small cell lung cancer.
Topics: Aged; Antigens, Surface; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Carcinoma, Non- | 2017 |
Nitric oxide-donating aspirin (NO-Aspirin) suppresses lung tumorigenesis in vitro and in vivo and these effects are associated with modulation of the EGFR signaling pathway.
Topics: A549 Cells; Animals; Aspirin; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2018 |
Racial and Ethnic Differences in the Relationship between Aspirin Use and Non-Small Cell Lung Cancer Risk and Survival.
Topics: Aspirin; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Ethnicity; Female; Humans; Lung Neopl | 2018 |
Aspirin use and racial differences in Non-Small cell lung cancer survival: What is the plot?
Topics: Aspirin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Racial Groups; Survival Rate | 2018 |
Aspirin inhibits hypoxia-mediated lung cancer cell stemness and exosome function.
Topics: A549 Cells; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell H | 2019 |
Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug.
Topics: Aspirin; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Epithelial-Mese | 2016 |
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.
Topics: Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensiv | 2008 |
Aspirin and non-small cell lung cancer resections: effect on long-term survival.
Topics: Aged; Aspirin; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cyclooxygenase 2 Inhibitors; | 2010 |
Combination of photodynamic therapy with aspirin in human-derived lung adenocarcinoma cells affects proteasome activity and induces apoptosis.
Topics: Apoptosis; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Humans; Lung Neopl | 2010 |
Regular aspirin use and lung cancer risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small C | 2002 |
Regular adult aspirin use decreases the risk of non-small cell lung cancer among women.
Topics: Acetaminophen; Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body M | 2008 |
Aspirin and lung cancer in women.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Non-Small-Cell Lung; Carci | 2002 |