Page last updated: 2024-10-23

aspirin and Carcinoma, Lewis Lung

aspirin has been researched along with Carcinoma, Lewis Lung in 5 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.

Research Excerpts

ExcerptRelevanceReference
" The present study investigated the effect of an authentic COX inhibitor, aspirin, on regional lymph node metastasis during the development of lung cancer in mice."3.80Aspirin reduces lung cancer metastasis to regional lymph nodes. ( Amano, H; Hosono, K; Ito, Y; Kitasato, H; Majima, M; Matsui, Y; Ogawa, F; Satoh, Y, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Wang, JD1
Chen, WY1
Li, JR1
Lin, SY1
Wang, YY1
Wu, CC1
Liao, SL1
Ko, CC1
Chen, CJ1
Palladino, M1
Gatto, I1
Neri, V1
Straino, S1
Smith, RC1
Silver, M1
Gaetani, E1
Marcantoni, M1
Giarretta, I1
Stigliano, E1
Capogrossi, M1
Hlatky, L1
Landolfi, R1
Pola, R1
Ogawa, F1
Amano, H2
Ito, Y1
Matsui, Y1
Hosono, K1
Kitasato, H2
Satoh, Y1
Majima, M2
Wong, CC1
Cheng, KW1
Papayannis, I1
Mattheolabakis, G1
Huang, L1
Xie, G1
Ouyang, N1
Rigas, B1
Yoshida, S1
Hayashi, I1
Kamata, M1
Inukai, M1
Yoshimura, H1

Other Studies

5 other studies available for aspirin and Carcinoma, Lewis Lung

ArticleYear
Aspirin Mitigated Tumor Growth in Obese Mice Involving Metabolic Inhibition.
    Cells, 2020, 02-28, Volume: 9, Issue:3

    Topics: Animals; Aspirin; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diet,

2020
Angiogenic impairment of the vascular endothelium: a novel mechanism and potential therapeutic target in muscular dystrophy.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:12

    Topics: Animals; Apoptosis; Aspirin; Carcinoma, Lewis Lung; Caveolin 1; Cell Movement; Cell Proliferation; C

2013
Aspirin reduces lung cancer metastasis to regional lymph nodes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:1

    Topics: Animals; Aspirin; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Green Fluorescent Proteins; Lung

2014
Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: implications for their clinical pharmacology.
    Pharmaceutical research, 2015, Volume: 32, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carboxylic Ester H

2015
COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:10

    Topics: Animals; Antibodies, Blocking; Aspirin; Benzenesulfonates; Carcinoma, Lewis Lung; Cyclooxygenase Inh

2003