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aspirin and Carcinoma, Intraepithelial

aspirin has been researched along with Carcinoma, Intraepithelial in 6 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the recurrence-free survival (RFS) rate of patients taking cardioprotective aspirin after intravesical bacille Calmette-Guérin (BCG) for high-grade noninvasive urothelial carcinoma of the bladder, as preventing the recurrence of superficial bladder cancer might decrease patient morbidity and mortality from this disease, and nonsteroidal anti-inflammatory agents (NSAIDs) have shown promise in preclinical prevention through inhibition of the prostaglandin pathway and other mechanisms."7.75Reduced bladder cancer recurrence rate with cardioprotective aspirin after intravesical bacille Calmette-Guérin. ( Bruskewitz, RC; Gee, JR; Hedican, SP; Jarrard, DF; Leverson, GE; Messing, EM; Moon, TD; Nakada, SY, 2009)
"To evaluate the recurrence-free survival (RFS) rate of patients taking cardioprotective aspirin after intravesical bacille Calmette-Guérin (BCG) for high-grade noninvasive urothelial carcinoma of the bladder, as preventing the recurrence of superficial bladder cancer might decrease patient morbidity and mortality from this disease, and nonsteroidal anti-inflammatory agents (NSAIDs) have shown promise in preclinical prevention through inhibition of the prostaglandin pathway and other mechanisms."3.75Reduced bladder cancer recurrence rate with cardioprotective aspirin after intravesical bacille Calmette-Guérin. ( Bruskewitz, RC; Gee, JR; Hedican, SP; Jarrard, DF; Leverson, GE; Messing, EM; Moon, TD; Nakada, SY, 2009)
"Furthermore, development of invasive pancreatic cancer in LsL-Kras(G12D); LsL-Trp53(R172H); Pdx1-Cre transgenic mice was partially inhibited by enalapril and aspirin."1.36The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer. ( Bartsch, DK; Buchholz, M; Chen, NM; Feldmann, G; Fendrich, V; Maitra, A; Neef, M; Slater, EP; Waldmann, J, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gee, JR1
Jarrard, DF1
Bruskewitz, RC1
Moon, TD1
Hedican, SP1
Leverson, GE1
Nakada, SY1
Messing, EM1
Fendrich, V1
Chen, NM1
Neef, M1
Waldmann, J1
Buchholz, M1
Feldmann, G1
Slater, EP1
Maitra, A1
Bartsch, DK1
Rao, CV1
Mohammed, A1
Janakiram, NB1
Li, Q1
Ritchie, RL1
Lightfoot, S1
Vibhudutta, A1
Steele, VE1
P'ng, KB1
Walsh, MD1
Seymour, GJ1
Lavin, MF1
Gardiner, RA1
Witjes, JA1
vd Meijden, AP1
Doesburg, W1
Debruyne, FM1
Nightingale, SL1

Trials

1 trial available for aspirin and Carcinoma, Intraepithelial

ArticleYear
From the Food and Drug Administration.
    JAMA, 1990, Aug-08, Volume: 264, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Aspirin; BCG Vaccine; Carcinoma in Situ; Clinical Trials as Topi

1990

Other Studies

5 other studies available for aspirin and Carcinoma, Intraepithelial

ArticleYear
Reduced bladder cancer recurrence rate with cardioprotective aspirin after intravesical bacille Calmette-Guérin.
    BJU international, 2009, Volume: 103, Issue:6

    Topics: Administration, Intravesical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents;

2009
The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer.
    Gut, 2010, Volume: 59, Issue:5

    Topics: Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticarcinogenic Agents; Aspirin; Carci

2010
Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Aspirin; beta Catenin; Body Weight; Carcinoma in Situ; Carcinoma,

2012
The adverse effect of fibrin-clot inhibiting drugs on intravesical bacillus Calmette-Guérin efficacy for superficial bladder cancer.
    The Australian and New Zealand journal of surgery, 1993, Volume: 63, Issue:2

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroida

1993
Influence of fibrin clot inhibitors on the efficacy of intravesical Bacillus Calmette-Guérin in the treatment of superficial bladder cancer. The Dutch Southeast Cooperative Urological Group.
    European urology, 1993, Volume: 23, Issue:3

    Topics: Administration, Intravesical; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; BCG

1993