aspirin has been researched along with Cancer of Skin in 75 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of aspirin on melanoma are unclear, with studies reporting conflicting results." | 9.51 | Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodriguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "Although aspirin is recommended for the prevention of colorectal cancer (CRC) among adults aged 50 to 59 years, recent data from a randomized clinical trial suggest a lack of benefit and even possible harm among older adults." | 9.41 | Aspirin Use and Risk of Colorectal Cancer Among Older Adults. ( Cao, Y; Chan, AT; Drew, DA; Giovannucci, EL; Guo, CG; Joshi, AD; Leung, WK; Ma, W; Meyerhardt, JA; Ng, K; Nguyen, LH; Ogino, S; Song, M, 2021) |
| "BCC incidence was evaluated in a randomized, double-blind, placebo-controlled clinical trial of aspirin (81 mg daily or 325 mg daily for ~3 years) and/or folic acid (1 mg daily for ~6 years) for the prevention of colorectal adenomas among 1121 participants with a previous adenoma." | 9.27 | Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas. ( Baron, JA; Barry, EL; Bresalier, RS; Gangar, P; Karagas, MR; McKeown-Eyssen, G; Passarelli, MN; Rees, JR; Zhang, D, 2018) |
| "ᅟ: We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group." | 9.22 | Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial. ( Atri, A; Engheta, A; Hadadi Abianeh, S; Sanatkarfar, M, 2016) |
| "In an attempt to increase the antitumor effect of cisplatin (50 mg/m2) and dacarbazine (350 mg/m2), each repeated on days 1 to 3 every 4 weeks in patients with metastatic melanoma, tamoxifen was added to the regimen." | 9.07 | High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma. ( Buzaid, AC; Durivage, HJ; Murren, JR, 1991) |
| "The association between hypertension and melanoma is unclear, and previous analyses of data from the ASPirin in Reducing Events in the Elderly (ASPREE) study demonstrated a reduced number of invasive melanoma events amongst aspirin-exposed hypertensive individuals." | 8.12 | Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodríguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "Determine whether aspirin confers longer survival in patients with melanoma." | 7.88 | Postdiagnosis aspirin use and overall survival in patients with melanoma. ( Lautenschlaeger, T; Li, H; Li, Z; Rachidi, S; Wallace, K, 2018) |
| "In the current work, we investigated the biochemical toxicity of acetylsalicylic acid (ASA; Aspirin) in human melanoma cell lines using tyrosinase enzyme as a molecular cancer therapeutic target." | 7.74 | Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines. ( Moridani, MY; Vad, NM; Yount, G, 2008) |
| "Melanoma is the most aggressive and fatal type of skin cancer due to being highly proliferative." | 5.56 | Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis. ( Abou-Kheir, W; Ausina, P; Branco, JR; Demaria, TM; Esteves, AM; Leandro, JGB; Mendonça, APM; Ochioni, AC; Oliveira, MF; Palhano, FL; Sola-Penna, M; Zancan, P, 2020) |
| "The effects of aspirin on melanoma are unclear, with studies reporting conflicting results." | 5.51 | Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodriguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "Although aspirin is recommended for the prevention of colorectal cancer (CRC) among adults aged 50 to 59 years, recent data from a randomized clinical trial suggest a lack of benefit and even possible harm among older adults." | 5.41 | Aspirin Use and Risk of Colorectal Cancer Among Older Adults. ( Cao, Y; Chan, AT; Drew, DA; Giovannucci, EL; Guo, CG; Joshi, AD; Leung, WK; Ma, W; Meyerhardt, JA; Ng, K; Nguyen, LH; Ogino, S; Song, M, 2021) |
| "BCC incidence was evaluated in a randomized, double-blind, placebo-controlled clinical trial of aspirin (81 mg daily or 325 mg daily for ~3 years) and/or folic acid (1 mg daily for ~6 years) for the prevention of colorectal adenomas among 1121 participants with a previous adenoma." | 5.27 | Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas. ( Baron, JA; Barry, EL; Bresalier, RS; Gangar, P; Karagas, MR; McKeown-Eyssen, G; Passarelli, MN; Rees, JR; Zhang, D, 2018) |
| "ᅟ: We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group." | 5.22 | Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial. ( Atri, A; Engheta, A; Hadadi Abianeh, S; Sanatkarfar, M, 2016) |
| "In an attempt to increase the antitumor effect of cisplatin (50 mg/m2) and dacarbazine (350 mg/m2), each repeated on days 1 to 3 every 4 weeks in patients with metastatic melanoma, tamoxifen was added to the regimen." | 5.07 | High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma. ( Buzaid, AC; Durivage, HJ; Murren, JR, 1991) |
| "Aspirin and other NSAIDs are showing promise in the chemoprevention of colorectal cancer." | 4.80 | Non-steroidal anti-inflammatory drugs and chemoprevention of cancer. ( Morgan, G; Vainio, H, 2000) |
| "The association between hypertension and melanoma is unclear, and previous analyses of data from the ASPirin in Reducing Events in the Elderly (ASPREE) study demonstrated a reduced number of invasive melanoma events amongst aspirin-exposed hypertensive individuals." | 4.12 | Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodríguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "Determine whether aspirin confers longer survival in patients with melanoma." | 3.88 | Postdiagnosis aspirin use and overall survival in patients with melanoma. ( Lautenschlaeger, T; Li, H; Li, Z; Rachidi, S; Wallace, K, 2018) |
| " In a cross-sectional study of 787 patients with newly diagnosed clinical stage IB or II melanoma, we estimated odds ratios for the association of proinflammatory factors (high body mass index, diabetes, cardiovascular disease, hypertension, and smoking) or the use of anti-inflammatory medications (statins, aspirin, corticosteroids, and nonsteroidal anti-inflammatory drugs), with ulcerated primary melanoma using regression models and subgroup analyses to control for melanoma thickness and mitotic rate." | 3.85 | Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma. ( Green, AC; Hughes, MCB; Khosrotehrani, K; Malt, M; Smith, D; Smithers, BM; van der Pols, JC; von Schuckmann, LA, 2017) |
| "Neither aspirin nor non-aspirin NSAID use was associated with a lower risk of melanoma, SCC, or BCC, even for women with high quantity, frequency, or duration of use." | 3.78 | Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses' Health Study. ( Alberts, DS; Feskanich, D; Han, J; Jeter, JM; Martinez, ME; Qureshi, AA, 2012) |
| " Due to the structural resemblance of DBM to the anti-inflammatory curcumin and an aspirin-like skeleton of DBM derivatives, we tested the anti-inflammatory effects of DBM and its derivatives, 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor promotion as well as TPA- and arachidonic acid-induced mouse ear edema in skin of CD-1 mice." | 3.77 | Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin. ( Ho, CT; Huang, MT; Lin, CC; Liu, Y, 2011) |
| "In the current work, we investigated the biochemical toxicity of acetylsalicylic acid (ASA; Aspirin) in human melanoma cell lines using tyrosinase enzyme as a molecular cancer therapeutic target." | 3.74 | Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines. ( Moridani, MY; Vad, NM; Yount, G, 2008) |
| " However, severe and numerous adverse events are associated with vismodegib use." | 2.52 | Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety. ( Ash, MM; Jolly, PS, 2015) |
| "UVR promotes skin cancer through multiple mechanisms, including induction of inflammation, oxidative stress, and DNA damage such as 8-oxoguanine and cyclobutane pyrimidine dimers." | 1.62 | Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo. ( Boucher, KM; Burd, CE; Florell, SR; Grossman, D; Kumar, D; Liu, T; Lum, D; Okwundu, N; Rahman, H; VanBrocklin, MW, 2021) |
| "Melanoma is the most aggressive and fatal type of skin cancer due to being highly proliferative." | 1.56 | Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis. ( Abou-Kheir, W; Ausina, P; Branco, JR; Demaria, TM; Esteves, AM; Leandro, JGB; Mendonça, APM; Ochioni, AC; Oliveira, MF; Palhano, FL; Sola-Penna, M; Zancan, P, 2020) |
| "Aspirin use was associated with reduced risk of SCC (HR 0·77, 95% confidence interval 0·64-0·93) only among infrequent (less than weekly) users and was not associated with BCC." | 1.51 | Aspirin and nonsteroidal anti-inflammatory drug use and keratinocyte cancers: a large population-based cohort study of skin cancer in Australia. ( Dusingize, JC; Green, AC; Neale, RE; Olsen, CM; Pandeya, N; Thompson, BS; Whiteman, DC, 2019) |
| "Head and neck skin cancer surgery using a full thickness skin graft is a common procedure." | 1.48 | Antithrombotic treatment and risk of complications after head and neck full thickness skin graft surgery. ( Ekström, M; Hasselgren, M; Janson, P; Runer, T, 2018) |
| "However, in women with a history of skin cancer, regular NSAID use was associated with 18% lower odds of NMSC." | 1.40 | Non-melanoma skin cancer and NSAID use in women with a history of skin cancer in the Women's Health Initiative. ( Ally, MS; Desai, M; Gamba, CS; Seiffert-Sinha, K; Sinha, AA; Stefanick, ML; Swetter, SM; Tang, JY; Wysong, A, 2014) |
| " Long-term use of NSAIDs, especially ASA, is associated with a significantly decreased risk of CM development." | 1.37 | Long-term use of nonsteroidal anti-inflammatory drugs decreases the risk of cutaneous melanoma: results of a United States case-control study. ( Atkins, MB; Curiel-Lewandrowski, C; Gomez, ML; Hollestein, LM; Nijsten, T; Stern, RS, 2011) |
| " As determined by Toxilight-cytotoxicity assay, the drug was only toxic to the cancer cells at 100 microM." | 1.33 | Cytostatic and cytotoxic effects of cyclooxygenase inhibitors and their synergy with docosahexaenoic acid on the growth of human skin melanoma A-375 cells. ( Chiu, LC; Ooi, VE; Tong, KF, 2005) |
| "The incidence of significant postoperative hemorrhage in the aspirin and nonaspirin groups was 5 (1." | 1.33 | Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk? ( Dhiwakar, M; Khan, NA; McClymont, LG, 2006) |
| "Kasabach-Merritt syndrome is an infrequent combination of a giant hemangioma and severe thrombocytopenia." | 1.30 | -Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma-. ( Dupont, D; Golkar, A; Valla, JS; Velin, P, 1998) |
| "In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value." | 1.28 | Blue rubber-bleb naevus syndrome: report of a case with consumption coagulopathy complicated by manifest thrombosis. ( Bouquet, J; Hofhuis, WJ; Oranje, AP; Sinaasappel, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.33) | 18.7374 |
| 1990's | 5 (6.67) | 18.2507 |
| 2000's | 26 (34.67) | 29.6817 |
| 2010's | 35 (46.67) | 24.3611 |
| 2020's | 8 (10.67) | 2.80 |
| Authors | Studies |
|---|---|
| Okwundu, N | 2 |
| Rahman, H | 2 |
| Liu, T | 2 |
| Florell, SR | 2 |
| Boucher, KM | 2 |
| Grossman, D | 3 |
| Yan, MK | 2 |
| Orchard, SG | 2 |
| Adler, NR | 2 |
| Wolfe, R | 2 |
| McLean, C | 2 |
| Rodriguez, LM | 2 |
| Woods, RL | 2 |
| Gibbs, P | 2 |
| Chan, AT | 3 |
| Haydon, A | 2 |
| Mar, VJ | 2 |
| Shah, H | 1 |
| Frech, FS | 1 |
| Dreyfuss, I | 1 |
| Hernandez, L | 1 |
| Nouri, K | 1 |
| Rundle, CW | 1 |
| Dellavalle, RP | 1 |
| Kumar, D | 1 |
| Lum, D | 1 |
| Burd, CE | 1 |
| VanBrocklin, MW | 1 |
| Ausina, P | 1 |
| Branco, JR | 1 |
| Demaria, TM | 1 |
| Esteves, AM | 1 |
| Leandro, JGB | 1 |
| Ochioni, AC | 1 |
| Mendonça, APM | 1 |
| Palhano, FL | 1 |
| Oliveira, MF | 1 |
| Abou-Kheir, W | 1 |
| Sola-Penna, M | 1 |
| Zancan, P | 1 |
| Lobo, Y | 1 |
| Blake, T | 1 |
| Wheller, L | 1 |
| Guo, CG | 1 |
| Ma, W | 1 |
| Drew, DA | 1 |
| Cao, Y | 1 |
| Nguyen, LH | 1 |
| Joshi, AD | 1 |
| Ng, K | 1 |
| Ogino, S | 1 |
| Meyerhardt, JA | 1 |
| Song, M | 1 |
| Leung, WK | 1 |
| Giovannucci, EL | 1 |
| von Schuckmann, LA | 1 |
| Smith, D | 1 |
| Hughes, MCB | 1 |
| Malt, M | 1 |
| van der Pols, JC | 1 |
| Khosrotehrani, K | 1 |
| Smithers, BM | 1 |
| Green, AC | 4 |
| Rachidi, S | 1 |
| Wallace, K | 1 |
| Li, H | 1 |
| Lautenschlaeger, T | 1 |
| Li, Z | 1 |
| Gaskins, M | 1 |
| Dittmann, M | 1 |
| Eisert, L | 1 |
| Werner, RN | 1 |
| Dressler, C | 1 |
| Löser, C | 1 |
| Nast, A | 1 |
| Passarelli, MN | 1 |
| Barry, EL | 1 |
| Zhang, D | 1 |
| Gangar, P | 1 |
| Rees, JR | 1 |
| Bresalier, RS | 1 |
| McKeown-Eyssen, G | 1 |
| Karagas, MR | 2 |
| Baron, JA | 1 |
| Orrell, KA | 2 |
| Cices, AD | 1 |
| Guido, N | 1 |
| Majewski, S | 1 |
| Ibler, E | 1 |
| Huynh, T | 1 |
| Rangel, SM | 1 |
| Laumann, AE | 1 |
| Martini, MC | 1 |
| Rademaker, AW | 2 |
| West, DP | 2 |
| Nardone, B | 2 |
| Lichtenberger, LM | 1 |
| Burge, S | 1 |
| Hasselgren, M | 1 |
| Runer, T | 1 |
| Janson, P | 1 |
| Ekström, M | 1 |
| Hammami, MB | 1 |
| Gill, R | 1 |
| Thiruvengadam, N | 1 |
| Oh, DY | 1 |
| Beck, K | 1 |
| Mahadevan, U | 1 |
| Kattah, MG | 1 |
| Pandeya, N | 4 |
| Olsen, CM | 4 |
| Thompson, BS | 1 |
| Dusingize, JC | 1 |
| Neale, RE | 1 |
| Whiteman, DC | 2 |
| Abtahi, S | 1 |
| Oshagbemi, OA | 1 |
| van Veelen, A | 1 |
| van Geel, RMJM | 1 |
| Gamba, CA | 1 |
| Swetter, SM | 3 |
| Stefanick, ML | 2 |
| Kubo, J | 1 |
| Desai, M | 2 |
| Spaunhurst, KM | 1 |
| Sinha, AA | 2 |
| Asgari, MM | 1 |
| Sturgeon, S | 1 |
| Tang, JY | 3 |
| Mikulec, CD | 1 |
| Rundhaug, JE | 1 |
| Simper, MS | 1 |
| Lubet, RA | 1 |
| Fischer, SM | 1 |
| Ally, MS | 2 |
| Criado, PR | 1 |
| Alavi, A | 1 |
| Halpern, I | 1 |
| Sotto, MN | 1 |
| Kirsner, RS | 1 |
| Famenini, S | 2 |
| Young, LC | 1 |
| Vad, NM | 2 |
| Kudugunti, SK | 1 |
| Wang, H | 1 |
| Bhat, GJ | 1 |
| Moridani, MY | 2 |
| Goodman, JR | 1 |
| Ash, MM | 1 |
| Jolly, PS | 1 |
| Wysong, A | 1 |
| Gamba, CS | 1 |
| Seiffert-Sinha, K | 1 |
| Reinau, D | 1 |
| Surber, C | 1 |
| Jick, SS | 1 |
| Meier, CR | 1 |
| Muranushi, C | 2 |
| Duan, L | 1 |
| Young, L | 1 |
| Korsaga-Somé, N | 1 |
| Maruani, A | 1 |
| Abdo, I | 1 |
| Favrais, G | 1 |
| Lorette, G | 1 |
| Pelster, MW | 1 |
| Yoo, S | 1 |
| Engheta, A | 1 |
| Hadadi Abianeh, S | 1 |
| Atri, A | 1 |
| Sanatkarfar, M | 1 |
| Doherty, SD | 1 |
| Barrett, TL | 1 |
| Joseph, AK | 1 |
| Yount, G | 1 |
| Clouser, MC | 1 |
| Roe, DJ | 1 |
| Foote, JA | 1 |
| Harris, RB | 1 |
| Joosse, A | 1 |
| Koomen, ER | 1 |
| Casparie, MK | 1 |
| Herings, RM | 1 |
| Guchelaar, HJ | 1 |
| Nijsten, T | 2 |
| Walsh, SN | 1 |
| Kerchner, K | 1 |
| Sangüeza, OP | 1 |
| Ghannoum, JE | 1 |
| Odingo, NA | 1 |
| Provost, N | 1 |
| Curiel-Lewandrowski, C | 1 |
| Gomez, ML | 1 |
| Hollestein, LM | 1 |
| Atkins, MB | 1 |
| Stern, RS | 1 |
| Torti, DC | 1 |
| Christensen, BC | 1 |
| Storm, CA | 1 |
| Fortuny, J | 1 |
| Perry, AE | 1 |
| Zens, MS | 1 |
| Stukel, T | 1 |
| Spencer, SK | 1 |
| Nelson, HH | 1 |
| Lin, CC | 1 |
| Liu, Y | 1 |
| Ho, CT | 1 |
| Huang, MT | 1 |
| Jeter, JM | 1 |
| Han, J | 1 |
| Martinez, ME | 1 |
| Alberts, DS | 1 |
| Qureshi, AA | 1 |
| Feskanich, D | 1 |
| Alam, M | 1 |
| Goldberg, LH | 2 |
| Bair, WB | 1 |
| Hart, N | 1 |
| Einspahr, J | 1 |
| Liu, G | 1 |
| Dong, Z | 2 |
| Alberts, D | 1 |
| Bowden, GT | 1 |
| Hawk, ET | 1 |
| Viner, JL | 1 |
| Umar, A | 1 |
| Lakhani, SR | 1 |
| Funk, JO | 1 |
| Alcalay, J | 1 |
| Alkalay, R | 1 |
| Kimyai-Asadi, A | 1 |
| Jih, MH | 1 |
| McCaffrey, P | 1 |
| Chiu, LC | 1 |
| Tong, KF | 1 |
| Ooi, VE | 1 |
| Fisher, GH | 1 |
| Geronemus, RG | 1 |
| Khalifeh, MR | 1 |
| Redett, RJ | 1 |
| Dhiwakar, M | 1 |
| Khan, NA | 1 |
| McClymont, LG | 1 |
| FitzGerald, K | 1 |
| Stephens, N | 1 |
| Newman, L | 1 |
| Venn, A | 1 |
| Holzmann, RD | 1 |
| Olbricht, SM | 1 |
| Thomas, VD | 1 |
| Schanbacher, CF | 1 |
| Jacobs, AH | 1 |
| Castell, P | 1 |
| Friedel, J | 1 |
| Siré, J | 1 |
| Lambert, D | 1 |
| Léauté-Labrèze, C | 1 |
| Bioulac-Sage, P | 1 |
| Labbé, L | 1 |
| Méraud, JP | 1 |
| Taïeb, A | 1 |
| Velin, P | 1 |
| Dupont, D | 1 |
| Golkar, A | 1 |
| Valla, JS | 1 |
| Worobec, AS | 1 |
| Vainio, H | 1 |
| Morgan, G | 1 |
| Samaniego, F | 1 |
| Pati, S | 1 |
| Karp, JE | 1 |
| Prakash, O | 1 |
| Bose, D | 1 |
| Maria, DA | 1 |
| Ribeiro, OG | 1 |
| Pizzocaro, KF | 1 |
| De Franco, M | 1 |
| Cabrera, WK | 1 |
| Starobinas, N | 1 |
| Gallois, V | 1 |
| Siqueira, M | 1 |
| Seman, M | 1 |
| Ibañez, OM | 1 |
| Bode, AM | 1 |
| Goolsby, MJ | 1 |
| Buzaid, AC | 1 |
| Murren, JR | 1 |
| Durivage, HJ | 1 |
| Hofhuis, WJ | 1 |
| Oranje, AP | 1 |
| Bouquet, J | 1 |
| Sinaasappel, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aspirin in Reducing Events in the Elderly[NCT01038583] | 19,114 participants (Actual) | Observational | 2010-01-31 | Active, not recruiting | |||
| [NCT00000611] | Phase 3 | 0 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for aspirin and Cancer of Skin
| Article | Year |
|---|---|
Perioperative anticoagulation recommendations for cutaneous oncologic surgery: a review of the literature.
Topics: Anticoagulants; Aspirin; Clopidogrel; Humans; Skin Neoplasms; Warfarin | 2022 |
Management of multiple trichoepithelioma: A review of pharmacological therapies.
Topics: Adalimumab; Administration, Topical; Anilides; Antineoplastic Agents; Aspirin; Humans; Imiquimod; La | 2021 |
Aspirin use and melanoma risk: a review of the literature.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Humans; Melanoma; Skin Ne | 2014 |
Aspirin and other NSAIDs as chemoprevention agents in melanoma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Chemoprevention; Hu | 2014 |
Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety.
Topics: Aged; Anilides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, | 2015 |
Aspirin and nonsteroidal anti-inflammatory drugs can prevent cutaneous squamous cell carcinoma: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Carcinoma, Squamous Cell; | 2015 |
Can oral nonsteroidal antiinflammatory drugs play a role in the prevention of basal cell carcinoma? A systematic review and metaanalysis.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Femal | 2016 |
Non-steroidal anti-inflammatory and cyclooxygenase-2-selective inhibitors in clinical cancer prevention trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Colorectal Neoplasms; Cy | 2003 |
Controversies in perioperative management of blood thinners in dermatologic surgery: continue or discontinue?
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Care; Intraoperative Complicat | 2004 |
Perioperative primary stroke: is aspirin cessation to blame?
Topics: Aged; Aspirin; Carcinoma, Basal Cell; Diagnosis, Differential; Drug Administration Schedule; Humans; | 2004 |
The management of patients on anticoagulants prior to cutaneous surgery: case report of a thromboembolic complication, review of the literature, and evidence-based recommendations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Damage, | 2006 |
Tufted angioma associated with platelet trapping syndrome: response to aspirin.
Topics: Aspirin; Biopsy; Blood Platelet Disorders; Child, Preschool; Combined Modality Therapy; Drug Therapy | 1997 |
Treatment of systemic mast cell disorders.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Antineoplastic Agents; Aspirin; Cholinergic An | 2000 |
Non-steroidal anti-inflammatory drugs and chemoprevention of cancer.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Carotene; Case-Control Studie | 2000 |
Signal transduction pathways: targets for chemoprevention of skin cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cell Transformat | 2000 |
7 trials available for aspirin and Cancer of Skin
| Article | Year |
|---|---|
A Randomized Double-blind Placebo-controlled Trial of Oral Aspirin for Protection of Melanocytic Nevi Against UV-induced DNA Damage.
Topics: Aspirin; DNA Damage; Humans; Nevus, Pigmented; Prospective Studies; Skin Neoplasms; Ultraviolet Rays | 2022 |
Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Male; Melanoma; Me | 2022 |
Aspirin Use and Risk of Colorectal Cancer Among Older Adults.
Topics: Aged; Aspirin; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Male; Middle Aged; Risk Fact | 2021 |
Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas.
Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Colorectal N | 2018 |
Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial.
Topics: Aged; Anticoagulants; Aspirin; Double-Blind Method; Female; Hemorrhage; Humans; Intraoperative Compl | 2016 |
Effect of non-steroidal anti-inflammatory drugs on non-melanoma skin cancer incidence in the SKICAP-AK trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arizona; Aspirin; Carcinoma, Basal | 2009 |
High-dose cisplatin with dacarbazine and tamoxifen in the treatment of metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cisplatin; Dacarbazine; Drug E | 1991 |
53 other studies available for aspirin and Cancer of Skin
| Article | Year |
|---|---|
Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Follow-Up Studies; Humans; Melanoma; Melanom | 2022 |
Nonsteroidal anti-inflammatory drug associations with nonmelanoma skin cancer - the saga continues.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Cohort Studies; Humans; Keratinocytes; | 2019 |
Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; DNA Damage; Kerat | 2021 |
Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; | 2020 |
Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectio | 2017 |
Postdiagnosis aspirin use and overall survival in patients with melanoma.
Topics: Academic Medical Centers; Adult; Aged; Analysis of Variance; Aspirin; Cohort Studies; Confidence Int | 2018 |
Management of antithrombotic agents in dermatologic surgery before and after publication of the corresponding German evidence-based guideline.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Aspirin; Biopsy; Clopidogrel; Evidence-Based M | 2018 |
Malignant melanoma associated with chronic once-daily aspirin exposure in males: A large, single-center, urban, US patient population cohort study from the "Research on Adverse Drug events And Report" (RADAR) project.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Aspirin; Case-Control Studi | 2018 |
Aspirin use and the risk of malignant melanoma.
Topics: Aspirin; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Melanoma; Sk | 2019 |
Reply to: "Aspirin use and the risk of malignant melanoma".
Topics: Aspirin; Humans; Melanoma; Skin Neoplasms | 2019 |
Antithrombotic treatment and risk of complications after head and neck full thickness skin graft surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Fibrinolytic Agents; He | 2018 |
Balancing the Checkpoint: Managing Colitis Associated with Dual Checkpoint Inhibitors and High-Dose Aspirin.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; As | 2019 |
Aspirin and nonsteroidal anti-inflammatory drug use and keratinocyte cancers: a large population-based cohort study of skin cancer in Australia.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Carcinoma, Squ | 2019 |
The role of misclassification of exposure in the association between aspirin and nonsteroidal anti-inflammatory drug use and keratinocyte cancers: reply from the authors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Cohort Studies; Humans; Keratinocytes; | 2019 |
The role of misclassification of exposure in the association between aspirin and nonsteroidal anti-inflammatory drug use and keratinocyte cancers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Cohort Studies; Humans; Keratinocytes; | 2019 |
Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women's Health Initiative.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Female; H | 2013 |
The chemopreventive efficacies of nonsteroidal anti-inflammatory drugs: the relationship of short-term biomarkers to long-term skin tumor outcome.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biomarkers, Tumor; Blotting, W | 2013 |
Role of aspirin and non-aspirin NSAIDs in preventing melanoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Melanoma; Randomized Controlled Trials as | 2013 |
Aspirin may lower melanoma risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Melanoma; Risk Factors; Skin Neoplasms; Wo | 2013 |
Unilateral livedoid vasculopathy associated with involutional phase of cutaneous infantile hemangioma: the connection to coagulation disorders.
Topics: Adolescent; Aspirin; Biopsy; Blood Coagulation Disorders; Blood Coagulation Tests; Diagnosis, Differ | 2013 |
Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice.
Topics: Alanine Transaminase; Animals; Anticarcinogenic Agents; Aspirin; Glutathione; Kidney; Lipid Peroxida | 2014 |
Non-melanoma skin cancer and NSAID use in women with a history of skin cancer in the Women's Health Initiative.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Logistic Mode | 2014 |
Nonsteroidal anti-inflammatory drugs and the risk of nonmelanoma skin cancer.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Ca | 2015 |
Aspirin use and melanoma: A UCLA pilot study.
Topics: Academic Medical Centers; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy, Needle; C | 2015 |
[Kasabach-Merritt phenomenon (KMP) exacerbated by platelet transfusions].
Topics: Aspirin; Axilla; Combined Modality Therapy; Compression Bandages; Disease Progression; Disseminated | 2015 |
Aspirin linked to preventing deadly skin cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Platelet Aggregation Inhibitors; Skin Neop | 2013 |
Use of an Abdominal Binder to Minimize Postprocedural Complications After Cutaneous Surgery on the Trunk.
Topics: Abdomen; Aged; Anticoagulants; Aspirin; Bandages; Humans; Male; Melanoma; Postoperative Hemorrhage; | 2016 |
Brooke-Spiegler syndrome: report of a case of multiple cylindromas and trichoepitheliomas.
Topics: Administration, Topical; Aspirin; Biomarkers, Tumor; Biopsy, Needle; Carcinoma, Adenoid Cystic; Carc | 2008 |
Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Benzoquinones; Cel | 2008 |
Non-steroidal anti-inflammatory drugs and melanoma risk: large Dutch population-based case-control study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Dat | 2009 |
Challenge. What is your diagnosis? Answer. Primary nodal diffuse large B-cell lymphoma with secondary cutaneous involvement.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; C | 2009 |
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; | 2009 |
Long-term use of nonsteroidal anti-inflammatory drugs decreases the risk of cutaneous melanoma: results of a United States case-control study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Case-Control | 2011 |
Analgesic and nonsteroidal anti-inflammatory use in relation to nonmelanoma skin cancer: a population-based case-control study.
Topics: Acetaminophen; Adult; Age Distribution; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; A | 2011 |
Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Carc | 2011 |
Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses' Health Study.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Carcinoma, S | 2012 |
Serious adverse vascular events associated with perioperative interruption of antiplatelet and anticoagulant therapy.
Topics: Aged; Anticoagulants; Aspirin; Carcinoma, Basal Cell; Clopidogrel; Drug Administration Schedule; Fem | 2002 |
Inhibitory effects of sodium salicylate and acetylsalicylic acid on UVB-induced mouse skin carcinogenesis.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Aspirin; Biopsy, Needle; Cell Transformat | 2002 |
Putting the brakes on cylindromatosis?
Topics: Apoptosis; Aspirin; Deubiquitinating Enzyme CYLD; Humans; Mutation; Neoplasms, Adnexal and Skin Appe | 2004 |
[Aspirin against cylindromatosis? Molecular functions of the CYLD tumor suppressor].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Carcinoma, Adenoid Cystic; Cell Transfo | 2004 |
Aspirin use reduces skin-cancer risk.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Case-Control Studies; Cy | 2006 |
Cytostatic and cytotoxic effects of cyclooxygenase inhibitors and their synergy with docosahexaenoic acid on the growth of human skin melanoma A-375 cells.
Topics: Antineoplastic Agents; Aspirin; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Cyclooxygen | 2005 |
Treatment of multiple familial trichoepitheliomas with a combination of aspirin and a neutralizing antibody to tumor necrosis factor alpha: A case report and hypothesis of mechanism.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aspirin; Carcinoma; Di | 2006 |
Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk?
Topics: Aged; Aspirin; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Male; Multivariate Analysis; | 2006 |
Inaccuracies in self-reported histories of non-melanoma skin cancer.
Topics: Aspirin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; False Negative Reactions; False Positive R | 2007 |
Hemorrhagic foreign body granuloma after cutaneous surgery occurring in the setting of aspirin therapy or thrombocytopenia: a presentation of six cases.
Topics: Aged; Aged, 80 and over; Aspirin; Biopsy; Diagnosis, Differential; Female; Fibrinolytic Agents; Gran | 2008 |
What's new in pediatric dermatology.
Topics: Anti-Bacterial Agents; Aspirin; Epidermolysis Bullosa; Hexachlorocyclohexane; Humans; Impetigo; Infa | 1981 |
[Pseudolymphoma caused by cholesterol embolism].
Topics: Aspirin; Diagnosis, Differential; Embolism, Cholesterol; Foot Dermatoses; Humans; Lymphoma; Male; Mi | 1993 |
-Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma-.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Back; Glucocorticoids; Hemangioma; Humans; Infant, | 1998 |
Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation?
Topics: Amino Acid Motifs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chlorocebus aethiops; | 2001 |
Resistance to melanoma metastases in mice selected for high acute inflammatory response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Neoplasm; Antigens, Neoplasm; Aspirin; | 2001 |
Clinical practice guidelines. USPSTF recommendations.
Topics: Aspirin; Chlamydia Infections; Coronary Disease; Evidence-Based Medicine; Humans; Mass Screening; Pl | 2002 |
Blue rubber-bleb naevus syndrome: report of a case with consumption coagulopathy complicated by manifest thrombosis.
Topics: Anemia, Hemolytic; Aspirin; Dipyridamole; Disseminated Intravascular Coagulation; Female; Gastrointe | 1990 |