aspirin has been researched along with Cancer of Head in 33 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This double-blind, placebo controlled study compared the analgesic efficacy of piroxicam with acetylsalicylic acid (ASA) in patients having continuous pain with advanced head and neck cancers." | 9.07 | Comparison of piroxicam and acetylsalicylic acid for pain in head and neck cancers: a double-blind study. ( Andley, M; Gnanasekaran, N; Saxena, A, 1994) |
| "This double-blind, placebo controlled study compared the analgesic efficacy of piroxicam with acetylsalicylic acid (ASA) in patients having continuous pain with advanced head and neck cancers." | 5.07 | Comparison of piroxicam and acetylsalicylic acid for pain in head and neck cancers: a double-blind study. ( Andley, M; Gnanasekaran, N; Saxena, A, 1994) |
| "The study aimed to investigate the role of medical history (skin warts, Candida albicans, herpetic lesions, heartburn, regurgitation) and medication use (for heartburn; for regurgitation; aspirin) in the aetiology of upper aerodigestive tract (UADT) cancer." | 3.78 | Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study. ( Agudo, A; Ahrens, W; Barzan, L; Benhamou, S; Bouchardy, C; Brennan, P; Canova, C; Castellsague, X; Conway, DI; Healy, CM; Kjaerheim, K; Lagiou, A; Lagiou, P; Macfarlane, GJ; Macfarlane, TV; Marron, M; McCartan, BE; McKinney, PA; Merletti, F; Plzak, J; Pohlabeln, H; Richiardi, L; Simonato, L; Slamova, A; Sloan, P; Talamini, R; Thakker, NS; Thomson, P; Znaor, A, 2012) |
| "Evidence for NSAIDs preventing head and neck cancer (HNC) is conflicting." | 2.47 | Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer: a systematic review. ( Anderson, LA; Hughes, CM; Murray, LJ; Wilson, JC, 2011) |
| "We identified 10 770 patients with HNSCC during a median follow-up of 3." | 1.72 | Low-dose aspirin use and mortality risk in patients with head and neck cancer: A nationwide cohort study of 10 770 patients. ( Carlander, AF; de la Cour, CD; Dehlendorff, C; Friis, S; Garset-Zamani, M; Grønhøj, C; Kjaer, SK; von Buchwald, C, 2022) |
| "Among 10,770 head and neck cancer 1-year survivors, the HR for cancer-specific mortality with non-aspirin NSAID use was 1." | 1.72 | Non-aspirin NSAIDs and head and neck cancer mortality in a Danish nationwide cohort study. ( Carlander, AF; de la Cour, CD; Dehlendorff, C; Friis, S; Garset-Zamani, M; Grønhøj, C; Kjaer, SK; von Buchwald, C, 2022) |
| "Aspirin or NSAID use was considered positive if the patients were receiving aspirin or NSAID medication from HNSCC diagnosis to at least 1 year after treatment initiation." | 1.48 | Aspirin use and head and neck cancer survival: an observational study of 11,623 person-years follow-up. ( Choi, SH; Kim, SA; Kim, SB; Kim, SY; Nam, SY; Roh, JL, 2018) |
| "Head and neck skin cancer surgery using a full thickness skin graft is a common procedure." | 1.48 | Antithrombotic treatment and risk of complications after head and neck full thickness skin graft surgery. ( Ekström, M; Hasselgren, M; Janson, P; Runer, T, 2018) |
| "Radiation-treated head and neck cancer (HNC) patients are at high risk for developing radiation vasculopathy, as evidenced by an increased stroke risk." | 1.42 | Carotid intima-media thickness measurement promises to improve cardiovascular risk evaluation in head and neck cancer patients. ( Ahn, P; deGoma, E; Hajj, J; Jacoby, D; Javaheri, A; Lin, A; Quon, H, 2015) |
| "Ketorolac use was not associated with need for transfusion (P = ." | 1.40 | Ketorolac after free tissue transfer: a comparative effectiveness study. ( Bayon, R; Chang, KE; Pagedar, NA; Schleiffarth, JR; Van Daele, DJ, 2014) |
| "Aspirin was prescribed in a quarter of cases and controls, COX-2 inhibitors in 4% of cases and 5% of controls and other NSAIDs in 33% of cases and 36% of controls." | 1.40 | Aspirin and non-steroidal anti-inflammatory drug use and the risk of upper aerodigestive tract cancer. ( Lefevre, K; Macfarlane, TV; Watson, MC, 2014) |
| " The aim of this retrospective study was to measure the therapeutic response to standard dosing with LMWH (using anti-Xa) in patients after ablative and reconstructive surgery for head and neck cancer, and to review the associated risk of bleeding." | 1.39 | Low molecular weight heparin in patients undergoing free tissue transfer following head and neck ablative surgery: review of efficacy and associated complications. ( Eley, KA; Parker, RJ; Watt-Smith, SR, 2013) |
| "Though dextran 40 did not result in any significant adverse local or systemic complications, it is not useful as a postoperative antithrombotic agent in head and neck oncologic reconstruction with free tissue transfer." | 1.39 | Safety and efficacy of low molecular weight dextran (dextran 40) in head and neck free flap reconstruction. ( Duraisamy, S; Iyer, S; Jayaprasad, K; Mathew, J; Paul, J; Rajan, S; Sharma, M; Thankappan, K, 2013) |
| "Aspirin use was associated with a 25% reduction in the risk of head and neck cancer (adjusted odds ratio, 0." | 1.33 | Chemoprevention of head and neck cancer with aspirin: a case-control study. ( Jayaprakash, V; Loree, TR; Menezes, RJ; Moysich, KB; Nasca, MA; Reid, ME; Rigual, NR, 2006) |
| "The incidence of significant postoperative hemorrhage in the aspirin and nonaspirin groups was 5 (1." | 1.33 | Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk? ( Dhiwakar, M; Khan, NA; McClymont, LG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 18 (54.55) | 24.3611 |
| 2020's | 6 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| de la Cour, CD | 3 |
| von Buchwald, C | 3 |
| Dehlendorff, C | 3 |
| Garset-Zamani, M | 2 |
| Grønhøj, C | 2 |
| Carlander, AF | 2 |
| Friis, S | 3 |
| Kjaer, SK | 3 |
| Iovoli, AJ | 1 |
| Hermann, GM | 1 |
| Ma, SJ | 1 |
| Platek, AJ | 1 |
| Farrugia, MK | 1 |
| Yau, E | 1 |
| Wooten, KE | 1 |
| Arshad, H | 1 |
| Gupta, V | 1 |
| Kuriakose, MA | 1 |
| Hicks, WL | 1 |
| Singh, AK | 1 |
| Verdoodt, F | 1 |
| Aalborg, GL | 1 |
| Clark, CM | 1 |
| Newark, AC | 1 |
| Fokar, A | 1 |
| Maxwell, JH | 2 |
| Saka-Herrán, C | 1 |
| Jané-Salas, E | 1 |
| Estrugo-Devesa, A | 1 |
| López-López, J | 1 |
| Kim, SA | 1 |
| Roh, JL | 2 |
| Kim, SB | 1 |
| Choi, SH | 1 |
| Nam, SY | 1 |
| Kim, SY | 1 |
| Hasselgren, M | 1 |
| Runer, T | 1 |
| Janson, P | 1 |
| Ekström, M | 1 |
| Lumley, CJ | 1 |
| Kaffenberger, TM | 1 |
| Desale, S | 1 |
| Tefera, E | 1 |
| Han, CJ | 1 |
| Rafei, H | 1 |
| Dolan, RS | 1 |
| Goldman, D | 1 |
| El-Deiry, M | 1 |
| Kokabi, N | 1 |
| Bercu, ZL | 1 |
| Newsome, J | 1 |
| Martin, JG | 1 |
| Wilson, JC | 3 |
| Murray, LJ | 2 |
| Hughes, CM | 2 |
| Black, A | 1 |
| Anderson, LA | 2 |
| Eley, KA | 1 |
| Parker, RJ | 1 |
| Watt-Smith, SR | 1 |
| Jayaprasad, K | 1 |
| Mathew, J | 1 |
| Thankappan, K | 1 |
| Sharma, M | 1 |
| Duraisamy, S | 1 |
| Rajan, S | 1 |
| Paul, J | 1 |
| Iyer, S | 1 |
| Fernandez-Pineda, I | 1 |
| Lopez-Gutierrez, JC | 1 |
| Chocarro, G | 1 |
| Bernabeu-Wittel, J | 1 |
| Ramirez-Villar, GL | 1 |
| Schleiffarth, JR | 1 |
| Bayon, R | 1 |
| Chang, KE | 1 |
| Van Daele, DJ | 1 |
| Pagedar, NA | 1 |
| Eichhorn, W | 1 |
| Kluwe, L | 1 |
| Heiland, M | 1 |
| Gröbe, A | 1 |
| Macfarlane, TV | 2 |
| Lefevre, K | 1 |
| Watson, MC | 1 |
| Jacoby, D | 1 |
| Hajj, J | 1 |
| Javaheri, A | 1 |
| deGoma, E | 1 |
| Lin, A | 1 |
| Ahn, P | 1 |
| Quon, H | 1 |
| Becker, C | 1 |
| Jick, SS | 1 |
| Meier, CR | 1 |
| Tang, L | 1 |
| Hu, H | 1 |
| Liu, H | 1 |
| Jian, C | 1 |
| Wang, H | 1 |
| Huang, J | 1 |
| Kim, EH | 1 |
| Jang, H | 1 |
| Shin, D | 1 |
| Macfarlane, GJ | 1 |
| Thakker, NS | 1 |
| Benhamou, S | 1 |
| Bouchardy, C | 1 |
| Ahrens, W | 1 |
| Pohlabeln, H | 1 |
| Lagiou, P | 1 |
| Lagiou, A | 1 |
| Castellsague, X | 1 |
| Agudo, A | 1 |
| Slamova, A | 1 |
| Plzak, J | 1 |
| Merletti, F | 1 |
| Richiardi, L | 1 |
| Talamini, R | 1 |
| Barzan, L | 1 |
| Kjaerheim, K | 1 |
| Canova, C | 1 |
| Simonato, L | 1 |
| Conway, DI | 1 |
| McKinney, PA | 1 |
| Thomson, P | 1 |
| Sloan, P | 1 |
| Znaor, A | 1 |
| Healy, CM | 1 |
| McCartan, BE | 1 |
| Marron, M | 1 |
| Brennan, P | 1 |
| Abu-Yousef, MM | 1 |
| Larson, JH | 1 |
| Kuehn, DM | 1 |
| Wu, AS | 1 |
| Laroia, AT | 1 |
| Lang, S | 1 |
| Lauffer, L | 1 |
| Clausen, C | 1 |
| Löhr, I | 1 |
| Schmitt, B | 1 |
| Hölzel, D | 1 |
| Wollenberg, B | 1 |
| Gires, O | 1 |
| Kastenbauer, E | 1 |
| Zeidler, R | 1 |
| Disa, JJ | 1 |
| Polvora, VP | 1 |
| Pusic, AL | 1 |
| Singh, B | 1 |
| Cordeiro, PG | 1 |
| Funk, JO | 1 |
| Jayaprakash, V | 1 |
| Rigual, NR | 1 |
| Moysich, KB | 1 |
| Loree, TR | 1 |
| Nasca, MA | 1 |
| Menezes, RJ | 1 |
| Reid, ME | 1 |
| Dhiwakar, M | 1 |
| Khan, NA | 1 |
| McClymont, LG | 1 |
| Saxena, A | 1 |
| Andley, M | 1 |
| Gnanasekaran, N | 1 |
| Brawley, OW | 1 |
| Phillips, PH | 1 |
| Cheson, BD | 1 |
| Léauté-Labrèze, C | 1 |
| Bioulac-Sage, P | 1 |
| Labbé, L | 1 |
| Méraud, JP | 2 |
| Taïeb, A | 2 |
| Moimeaux, V | 1 |
| Legrain, V | 1 |
| Jimenez, M | 1 |
| Choussat, A | 1 |
| Maleville, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Postoperative Prostaglandin E1 in Head and Neck Microsurgery[NCT00733434] | Phase 4 | 242 participants (Anticipated) | Interventional | 2008-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Cancer of Head
| Article | Year |
|---|---|
Head and neck cancer and non-steroidal anti-inflammatory drugs: Systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Head and Neck Neoplasms; Humans; Neoplasm Recurren | 2021 |
Association of nonsteroidal anti-inflammatory drugs and aspirin use and the risk of head and neck cancers: a meta-analysis of observational studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Head and Neck Neoplasms; Humans; Ibuprofen; Observ | 2016 |
Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer: a systematic review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Head and Neck Neoplasms; Humans; Risk Factors | 2011 |
Tufted angioma associated with platelet trapping syndrome: response to aspirin.
Topics: Aspirin; Biopsy; Blood Platelet Disorders; Child, Preschool; Combined Modality Therapy; Drug Therapy | 1997 |
3 trials available for aspirin and Cancer of Head
| Article | Year |
|---|---|
Long-term outcome of vincristine-aspirin-ticlopidine (VAT) therapy for vascular tumors associated with Kasabach-Merritt phenomenon.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspirin; Child, Preschool; Ecchymosis; Female; Follo | 2013 |
Dextran-related complications in head and neck microsurgery: do the benefits outweigh the risks? A prospective randomized analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Dextrans; Female; Head a | 2003 |
Comparison of piroxicam and acetylsalicylic acid for pain in head and neck cancers: a double-blind study.
Topics: Adult; Aged; Aspirin; Clinical Protocols; Double-Blind Method; Female; Gastrointestinal Diseases; He | 1994 |
26 other studies available for aspirin and Cancer of Head
| Article | Year |
|---|---|
Low-dose aspirin use and mortality risk in patients with head and neck cancer: A nationwide cohort study of 10 770 patients.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Ma | 2022 |
Non-aspirin NSAIDs and head and neck cancer mortality in a Danish nationwide cohort study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; De | 2022 |
Association of Nonsteroidal Anti-inflammatory Drug Use With Survival in Patients With Squamous Cell Carcinoma of the Head and Neck Treated With Chemoradiation Therapy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoradiotherapy; Female; Head and Neck Neo | 2020 |
Low-dose aspirin use and risk of head and neck cancer-A Danish nationwide case-control study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Denmark; Head and Neck Neopl | 2021 |
Aspirin use predicts prolonged survival in patients with oropharyngeal cancer: Nationwide Veterans Affairs database study.
Topics: Aspirin; Head and Neck Neoplasms; Humans; Oropharyngeal Neoplasms; Proportional Hazards Models; Vete | 2021 |
Aspirin use and head and neck cancer survival: an observational study of 11,623 person-years follow-up.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamou | 2018 |
Antithrombotic treatment and risk of complications after head and neck full thickness skin graft surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Fibrinolytic Agents; He | 2018 |
Post-diagnosis aspirin use and survival in veterans with head and neck cancer.
Topics: Aged; Aspirin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Kaplan-Meier Estim | 2019 |
Image-Guided Percutaneous Gastrostomy Tube Placement is Safe in Patients Requiring Aspirin 325 mg.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Dose-Response Relationship, Drug; Female; Gastrostomy; Head | 2019 |
Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer.
Topics: Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Head and Neck Neop | 2013 |
Low molecular weight heparin in patients undergoing free tissue transfer following head and neck ablative surgery: review of efficacy and associated complications.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Dalteparin; Dose-Response Relationship, Dru | 2013 |
Safety and efficacy of low molecular weight dextran (dextran 40) in head and neck free flap reconstruction.
Topics: Adult; Aged; Aspirin; Dextrans; Female; Fibrinolytic Agents; Free Tissue Flaps; Graft Survival; Head | 2013 |
Ketorolac after free tissue transfer: a comparative effectiveness study.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Transplantation; Comparat | 2014 |
Lack of evidence for increased risk of postoperative bleeding after cutaneous surgery in the head and neck in patients taking aspirin.
Topics: Aged; Ambulatory Surgical Procedures; Aspirin; Dermatologic Surgical Procedures; Facial Neoplasms; F | 2014 |
Aspirin and non-steroidal anti-inflammatory drug use and the risk of upper aerodigestive tract cancer.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Con | 2014 |
Carotid intima-media thickness measurement promises to improve cardiovascular risk evaluation in head and neck cancer patients.
Topics: Aspirin; Cardiovascular Diseases; Carotid Intima-Media Thickness; Coronary Vessels; Female; Head and | 2015 |
Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: A case-control analysis.
Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Female; He | 2015 |
Aspirin plus sorafenib potentiates cisplatin cytotoxicity in resistant head and neck cancer cells through xCT inhibition.
Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Aspirin; Cell Line, Tumor; Cisplat | 2017 |
Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study.
Topics: Adult; Aspirin; Candidiasis; Carcinoma, Squamous Cell; Case-Control Studies; Disease Susceptibility; | 2012 |
Safety of ultrasound-guided fine needle aspiration biopsy of neck lesions in patients taking antithrombotic/anticoagulant medications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biopsy, Fine-Needle; Chi-Square | 2011 |
Impaired monocyte function in cancer patients: restoration with a cyclooxygenase-2 inhibitor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Cell Movement; Cyclooxyg | 2003 |
[Aspirin against cylindromatosis? Molecular functions of the CYLD tumor suppressor].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Carcinoma, Adenoid Cystic; Cell Transfo | 2004 |
Chemoprevention of head and neck cancer with aspirin: a case-control study.
Topics: Alcohol Drinking; Aspirin; Case-Control Studies; Confidence Intervals; Female; Head and Neck Neoplas | 2006 |
Surgical resection of cutaneous head and neck lesions: does aspirin use increase hemorrhagic risk?
Topics: Aged; Aspirin; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Male; Multivariate Analysis; | 2006 |
Cancer chemoprevention trials.
Topics: Adult; Aspirin; Colorectal Neoplasms; Double-Blind Method; Head and Neck Neoplasms; Humans; Isotreti | 1996 |
Aspirin-ticlopidin in Kasabach-Merritt syndrome.
Topics: Aspirin; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hemangioma; Humans; Infant; Thr | 1992 |