Page last updated: 2024-10-23

aspirin and Cancer of Cervix

aspirin has been researched along with Cancer of Cervix in 11 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
" Outcomes included 6 clinical quality measures of being up to date for colorectal cancer screening, cervical cancer screening, tobacco screening and cessation counseling, BMI screening and follow-up, depression screening and follow-up, and aspirin use for ischemic vascular disease."4.31The First Year of the COVID-19 Pandemic: Changes in Preventive Services in Community Health Centers. ( Bandi, P; Han, X; Jemal, A; Makaroff, LA; Minihan, AK; Star, J, 2023)
"Acetaminophen use was not associated with the risk of cervical cancer."1.42Aspirin and Acetaminophen Use and the Risk of Cervical Cancer. ( Cannioto, RA; Friel, G; Hampras, SS; Kolomeyevskaya, NV; Kruszka, B; Lele, SB; Liu, CS; Moysich, KB; Odunsi, KO; Schmitt, K, 2015)
"Viability of cervical cancer cell lines was assessed by the MTT method at various concentrations of aspirin and triptolide."1.39Enhanced anti-tumor efficacy of aspirin combined with triptolide in cervical cancer cells. ( Chen, RH; Tian, YJ, 2013)
"However, there are few reports about cervical cancer."1.36Aspirin inhibits ErbB2 to induce apoptosis in cervical cancer cells. ( He, Q; Sun, Z; Wang, Y; Xiang, S; Yan, F; Zhang, J, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Star, J1
Han, X1
Makaroff, LA1
Minihan, AK1
Jemal, A1
Bandi, P1
Das, S3
Ray, DK3
Sengupta, D3
Mahapatra, E3
Biswas, S3
Roy, M3
Mukherjee, S3
Zárate, GDSF1
Flores, FLR1
Burguete, AI1
Marina, VM1
Olea, EG1
Carranza, CO1
Melendrez, CG1
Morales, VHB1
Tuyaerts, S1
Van Nuffel, AMT1
Naert, E1
Van Dam, PA1
Vuylsteke, P1
De Caluwé, A1
Aspeslagh, S1
Dirix, P1
Lippens, L1
De Jaeghere, E1
Amant, F1
Vandecasteele, K1
Denys, H1
Xie, LX1
Hu, LN1
Chen, HX1
Peng, X1
Li, JK1
Chen, RH1
Tian, YJ1
Wilson, JC1
O'Rorke, MA1
Cooper, JA1
Murray, LJ1
Hughes, CM1
Gormley, GJ1
Anderson, LA1
Friel, G1
Liu, CS1
Kolomeyevskaya, NV1
Hampras, SS1
Kruszka, B1
Schmitt, K1
Cannioto, RA1
Lele, SB1
Odunsi, KO1
Moysich, KB1
Xiang, S1
Sun, Z1
He, Q1
Yan, F1
Wang, Y1
Zhang, J1
Im, SR1
Jang, YJ1
Mennie, AT1
Dalley, VM1
Dinneen, LC1
Collier, HO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Investigation of Pembrolizumab (Keytruda) in Combination With Radiation and an Immune Modulatory Cocktail in Patients With Cervical and Uterine Cancer (PRIMMO Trial)[NCT03192059]Phase 243 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for aspirin and Cancer of Cervix

ArticleYear
PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.
    BMC cancer, 2019, May-28, Volume: 19, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspirin; Chemoradiotherapy; Curcumin; Cycl

2019
Non-steroidal anti-inflammatory drug use and cervical cancer risk: a case-control study using the Clinical Practice Research Datalink.
    Cancer epidemiology, 2013, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-C

2013
Treatment of radiation-induced gastrointestinal distress with acetylsalicylate.
    Lancet (London, England), 1975, Nov-15, Volume: 2, Issue:7942

    Topics: Antacids; Aspirin; Buffers; Clinical Trials as Topic; Diarrhea; Drug Combinations; Drug Evaluation;

1975

Other Studies

8 other studies available for aspirin and Cancer of Cervix

ArticleYear
The First Year of the COVID-19 Pandemic: Changes in Preventive Services in Community Health Centers.
    American journal of preventive medicine, 2023, Volume: 64, Issue:2

    Topics: Aspirin; Colorectal Neoplasms; Community Health Centers; COVID-19; Early Detection of Cancer; Female

2023
Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Nov-01, Volume: 23, Issue:11

    Topics: Apoptosis; Aspirin; Aurora Kinase A; Cell Line, Tumor; Female; G2 Phase Cell Cycle Checkpoints; Huma

2022
Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Nov-01, Volume: 23, Issue:11

    Topics: Apoptosis; Aspirin; Aurora Kinase A; Cell Line, Tumor; Female; G2 Phase Cell Cycle Checkpoints; Huma

2022
Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Nov-01, Volume: 23, Issue:11

    Topics: Apoptosis; Aspirin; Aurora Kinase A; Cell Line, Tumor; Female; G2 Phase Cell Cycle Checkpoints; Huma

2022
Aspirin Restores Radiosensitivity in Cervical Cancer Cells by Inducing Mitotic Catastrophe through Downregulating G2/M Effectors.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Nov-01, Volume: 23, Issue:11

    Topics: Apoptosis; Aspirin; Aurora Kinase A; Cell Line, Tumor; Female; G2 Phase Cell Cycle Checkpoints; Huma

2022
Low-Dose Aspirin Has Antiproliferative and Apoptosis Effects in HPV16 Tumor Cells and Delays Tumor Development and Growth in an Experimental Model.
    Gynecologic and obstetric investigation, 2023, Volume: 88, Issue:3

    Topics: Animals; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Female; Human papillomavirus 16;

2023
[Effects of NF-kappaB inhibitor on cisplatin-induced apoptosis in cervical cancer].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2013, Volume: 44, Issue:1

    Topics: Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Curcumin; Female; Humans

2013
Enhanced anti-tumor efficacy of aspirin combined with triptolide in cervical cancer cells.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Apoptosis; Aspirin; bcl-

2013
Aspirin and Acetaminophen Use and the Risk of Cervical Cancer.
    Journal of lower genital tract disease, 2015, Volume: 19, Issue:3

    Topics: Acetaminophen; Adenocarcinoma; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-

2015
Aspirin inhibits ErbB2 to induce apoptosis in cervical cancer cells.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:2

    Topics: Apoptosis; Aspirin; Cell Line, Tumor; Cell Survival; Female; HeLa Cells; Humans; Proto-Oncogene Mas;

2010
Aspirin enhances TRAIL-induced apoptosis via regulation of ERK1/2 activation in human cervical cancer cells.
    Biochemical and biophysical research communications, 2012, Jul-20, Volume: 424, Issue:1

    Topics: Apoptosis; Aspirin; Caspases; Enzyme Activation; Female; HeLa Cells; Humans; MAP Kinase Signaling Sy

2012