aspirin has been researched along with Cacosmia in 6 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks." | 7.74 | Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008) |
| "Oral aspirin challenge (OAC) reveals aspirin-exacerbated respiratory disease (AERD) in approximately 50% of unselected patients with chronic rhinosinusitis with nasal polyposis (CRSwNP)." | 3.85 | Olfaction and sinonasal symptoms in patients with CRSwNP and AERD and without AERD: a cross-sectional and longitudinal study. ( Gudziol, V; Hummel, T; Koschel, D; Michel, M; Sonnefeld, C, 2017) |
| "Patients with chronic rhinosinusitis (CRS) and nasal polyps (NPs) may be subdivided into aspirin-sensitive (AS) and aspirin-tolerant (AT) populations." | 3.79 | Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps. ( Fountain, CR; Katial, RK; Kingdom, TT; Mudd, PA; Ramakrishnan, VR; Sillau, SH, 2013) |
| "Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks." | 3.74 | Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fountain, CR | 1 |
| Mudd, PA | 1 |
| Ramakrishnan, VR | 1 |
| Sillau, SH | 1 |
| Kingdom, TT | 1 |
| Katial, RK | 1 |
| Gudziol, V | 1 |
| Michel, M | 1 |
| Sonnefeld, C | 1 |
| Koschel, D | 1 |
| Hummel, T | 1 |
| Dursun, AB | 1 |
| Woessner, KA | 1 |
| Simon, RA | 1 |
| Karasoy, D | 1 |
| Stevenson, DD | 1 |
| Johansson, L | 1 |
| Brämerson, A | 1 |
| Holmberg, K | 1 |
| Melén, I | 1 |
| Akerlund, A | 1 |
| Bende, M | 1 |
| Bonfils, P | 1 |
| Avan, P | 1 |
| Malinvaud, D | 1 |
| Vento, SI | 1 |
| Ertama, LO | 1 |
| Hytönen, ML | 1 |
| Wolff, CH | 1 |
| Malmberg, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease[NCT00215787] | 20 participants (Actual) | Interventional | 2005-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Presence of Laryngopharyngeal reflux was measured by 24 hour pH impedance probe monitor per equipment manufacturer software. Two or more episodes in twenty four hours was considered positive, in accordance with published standards. (NCT00215787)
Timeframe: one year
| Intervention | participants (Number) |
|---|---|
| Lansoprazole | 15 |
6 other studies available for aspirin and Cacosmia
| Article | Year |
|---|---|
Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Drug Resistance; Eosinophils; Fe | 2013 |
Olfaction and sinonasal symptoms in patients with CRSwNP and AERD and without AERD: a cross-sectional and longitudinal study.
Topics: Adult; Aspirin; Asthma, Aspirin-Induced; Chronic Disease; Cross-Sectional Studies; Female; Humans; L | 2017 |
Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis.
Topics: Administration, Oral; Adult; Age Factors; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Exp | 2008 |
Clinical relevance of nasal polyps in individuals recruited from a general population-based study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Cross-Sectional Studies; Drug Hypersensitivity; Fem | 2004 |
Influence of allergy on the symptoms and treatment of nasal polyposis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Beclomethasone; Bronchial Provocation Test | 2006 |
Nasal polyposis: clinical course during 20 years.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Aspirin; Biopsy; D | 2000 |