aspirin has been researched along with Bronchial Spasm in 94 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intravenous (n = 21) and inhalational maintenance anaesthesia (n = 21) were compared by random allocation in patients with the aspirin intolerance syndrome undergoing endoscopic nasal procedures." | 9.08 | A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome. ( Novak-Jankovic, V; Paver-Erzen, V; Podboj, J, 1995) |
| "Urinary leukotriene E4 (LTE4) concentrations have been measured in six asthmatic patients with aspirin sensitivity and in five asthmatic subjects tolerant of aspirin, before and after provocation with aspirin or placebo." | 9.07 | Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. ( Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P, 1991) |
| "Forty-five patients with moderately severe perennial bronchial asthma were challenged by ingestion of: acetylsalicyclic acid (ASA); 4 azo dyes (tartrazine, sunset yellow, amaranth, and ponceau); 3 non-azo dyes (erythrosine, brilliant blue, and indigotin); sodium benzoate (NaB); parahydroxybenzoic acid (OHBA); butylated hydroxyanisole (BHA); and butylated hydroxytoluene (BHT)." | 9.04 | Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics. ( Hoffman, M; Nelson, HS; Raine, DA; Weber, RW, 1979) |
| "Oral challenge tests with acetylsalicylic acid, tartrazine or benzoic acid were performed in 7 intolerant asthmatic patients after a 3-day treatment with either orally taken ketotifen (1 mg twice daily) or inhaled disodium cromoglycate (20 mg four times daily) at random." | 9.04 | Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. ( Wüthrich, B, 1979) |
| "Patients who experience aspirin-sensitive asthma should be cautious when taking aspirin and NSAIDs, despite treatment with leukotriene inhibitors." | 8.81 | Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics. ( Pontikes, PJ; Volkman, JA, 2002) |
| "An intraoperative bronchospasm during sinus surgery is not a clear indicator of an aspirin intolerance syndrome." | 7.73 | [Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006) |
| "Aspirin inhibits cyclooxygenase activity and modifies production of the arachidonate cascade in aspirin-induced asthma." | 7.71 | Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients. ( Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, S, 2001) |
| " Upon preoperative medical evaluation, it was discovered that she was "allergic" to aspirin and suffered from stress-induced asthma." | 7.69 | Ketorolac-induced bronchospasm in an aspirin-intolerant patient. ( Bennett, CR; Chen, AH, 1994) |
| " During aspirin-induced bronchospasm, release of leukotriene B4 increased significantly (45." | 7.68 | Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. ( Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL, 1992) |
| " A 31-year-old female with intrinsic bronchial asthma and aspirin sensitivity was admitted to our hospital because of an episode of asthmatic attack." | 7.68 | [Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient]. ( Hirano, T; Kitada, O; Nakamura, H; Shiratusuki, N; Suenaga, N; Sugita, M; Uyama, O, 1990) |
| "Nineteen asthmatic patients, 11 with and eight without aspirin (ASA) intolerance were studied in order to test possible platelet and coagulation system involvement in the pathogenesis of aspirin-induced bronchoconstriction (AIB)." | 7.67 | Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics. ( Bednarowicz, A; Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1987) |
| "The role of a commonly ingested food additive, the preservative sodium metabisulfite (MBS), and aspirin (ASA), in chronic asthma has been studied in 29 children." | 7.67 | Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma. ( Mellis, CM; Towns, SJ, 1984) |
| "Nine patients with aspirin-induced bronchospasm were compared with age-matched normal controls to test the hypothesis that a defect in the beta-adrenergic system could lead to excessive dependence on prostaglandins to maintain bronchodilator function." | 7.66 | A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm. ( Conolly, ME; Fisher, HK; Hui, KK; Tashkin, DP; Wolfe, RN, 1982) |
| "Guacetisal was administered to a group of patients suffering from chronic asthmatic bronchitis." | 7.66 | [Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal]. ( Bande, G; Coghe, M; Meloni, M; Nonne, G, 1981) |
| "Eleven patients with intrinsic asthma and aspirin sensitivity were challenged with intravenous hydrocortisone sodium succinate (Solu-Cortef; the Upjohn Co." | 7.66 | Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. ( Dajani, BM; Hamzeh, YS; Shubair, KS; Sliman, NA, 1981) |
| "Pretreatment with montelukast allowed only one patient to proceed through all challenge doses of ASA without any reactions." | 5.31 | Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics. ( Christiansen, SC; Mathison, DA; Simon, RA; Stevenson, DD, 2000) |
| "The inhalation challenge with lysine-aspirin (L-ASA) using the dosimeter method allows the construction of a dose-response curve and the quantitative estimation of airway responsiveness to the drug." | 5.28 | Aspirin-induced asthma and bronchial hyperresponsiveness. ( Cocco, G; Masi, C; Melillo, E; Melillo, G; Padovano, A, 1991) |
| "We investigated whether omalizumab administration would be associated with attenuation of aspirin-provoked bronchospasm in patients with AERD undergoing aspirin desensitization." | 5.27 | Omalizumab can inhibit respiratory reaction during aspirin desensitization. ( Aronica, MA; Hazen, SL; Lang, DM; Maierson, ES; Vasas, DC; Wang, XF, 2018) |
| "Intravenous (n = 21) and inhalational maintenance anaesthesia (n = 21) were compared by random allocation in patients with the aspirin intolerance syndrome undergoing endoscopic nasal procedures." | 5.08 | A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome. ( Novak-Jankovic, V; Paver-Erzen, V; Podboj, J, 1995) |
| "Urinary leukotriene E4 (LTE4) concentrations have been measured in six asthmatic patients with aspirin sensitivity and in five asthmatic subjects tolerant of aspirin, before and after provocation with aspirin or placebo." | 5.07 | Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. ( Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P, 1991) |
| "Aspirin (ASA) and other non-steroidal anti-inflammatory drugs, which are cyclooxygenase (COX) inhibitors, precipitate asthmatic attacks in ASA-intolerant patients, while sodium salicylate, hardly active on COX by itself, is well tolerated by these patients." | 5.06 | Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients. ( Dworski, R; Nizankowska, E; Soja, J; Szczeklik, A, 1990) |
| "Oral challenge tests with acetylsalicylic acid, tartrazine or benzoic acid were performed in 7 intolerant asthmatic patients after a 3-day treatment with either orally taken ketotifen (1 mg twice daily) or inhaled disodium cromoglycate (20 mg four times daily) at random." | 5.04 | Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. ( Wüthrich, B, 1979) |
| "Forty-five patients with moderately severe perennial bronchial asthma were challenged by ingestion of: acetylsalicyclic acid (ASA); 4 azo dyes (tartrazine, sunset yellow, amaranth, and ponceau); 3 non-azo dyes (erythrosine, brilliant blue, and indigotin); sodium benzoate (NaB); parahydroxybenzoic acid (OHBA); butylated hydroxyanisole (BHA); and butylated hydroxytoluene (BHT)." | 5.04 | Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics. ( Hoffman, M; Nelson, HS; Raine, DA; Weber, RW, 1979) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) cause bronchospasm in susceptible patients with asthma, often termed aspirin-exacerbated respiratory disease (AERD), with the risk being greatest after acute exposure." | 4.90 | Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials. ( Donnan, PT; Guthrie, B; Jackson, C; Lipworth, BJ; Morales, DR; Santiago, VH, 2014) |
| " It has also been associated with a female predominance, aspirin-sensitive bronchospasm, and nasal polyposis." | 4.85 | Is intrinsic asthma synonymous with infection? ( Busse, WW; Dahlberg, PE, 2009) |
| " We report a patient with asthma, aspirin allergy, and nasal polyps who developed bronchospasm following the administration of intravenous methylprednisolone sodium succinate during an acute asthmatic attack." | 4.83 | Worsening of asthma with systemic corticosteroids. A case report and review of literature. ( Jackson, R; Reddymasu, S; Sheth, A, 2006) |
| "Patients who experience aspirin-sensitive asthma should be cautious when taking aspirin and NSAIDs, despite treatment with leukotriene inhibitors." | 4.81 | Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics. ( Pontikes, PJ; Volkman, JA, 2002) |
| "Aspirin intolerance manifests itself as an acute urticaria-angioedema, bronchospasm, severe rhinitis, or shock occurring within three hours of aspirin ingestion." | 4.76 | Aspirin and allergic diseases: a review. ( Settipane, GA, 1983) |
| "The term "aspirin intolerance" is defined as acute urticaria-angioedema, bronchospasm, severe rhinitis, or shock occurring within three hours of aspirin ingestion." | 4.76 | Adverse reactions of aspirin and related drugs. ( Settipane, GA, 1981) |
| " To carry out a case-control analysis between AGT and aspirin-induced bronchospasm following treatment with an anti-asthma drug, montelukast (MLK), 38 single nucleotide polymorphisms (SNPs) in AGT were genotyped in 56 AIA cohort." | 3.77 | Association of the variants in AGT gene with modified drug response in Korean aspirin-intolerant asthma patients. ( Bae, JS; Cheong, HS; Kim, JH; Kim, JM; Kim, Y; Lee, JS; Park, BL; Park, CS; Park, JS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| "Aspirin causes bronchospasm in patients with aspirin exacerbated respiratory disease (AERD)." | 3.74 | PGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory disease. ( Lau, HY; Leung, PS; Wang, XS; Wu, AY, 2007) |
| "An intraoperative bronchospasm during sinus surgery is not a clear indicator of an aspirin intolerance syndrome." | 3.73 | [Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006) |
| "Aspirin inhibits cyclooxygenase activity and modifies production of the arachidonate cascade in aspirin-induced asthma." | 3.71 | Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients. ( Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, S, 2001) |
| "Between 8-20 percent of adult asthmatics experience bronchospasm following ingestion of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.70 | NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority. ( Sturtevant, J, 1999) |
| " Upon preoperative medical evaluation, it was discovered that she was "allergic" to aspirin and suffered from stress-induced asthma." | 3.69 | Ketorolac-induced bronchospasm in an aspirin-intolerant patient. ( Bennett, CR; Chen, AH, 1994) |
| " During aspirin-induced bronchospasm, release of leukotriene B4 increased significantly (45." | 3.68 | Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. ( Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL, 1992) |
| "We describe four cases of anaphylaxis to paracetamol without co-existing aspirin intolerance and review the Australian experience in paracetamol anaphylaxis." | 3.68 | Paracetamol anaphylaxis. ( Czarny, D; Leung, R; Plomley, R, 1992) |
| " A 31-year-old female with intrinsic bronchial asthma and aspirin sensitivity was admitted to our hospital because of an episode of asthmatic attack." | 3.68 | [Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient]. ( Hirano, T; Kitada, O; Nakamura, H; Shiratusuki, N; Suenaga, N; Sugita, M; Uyama, O, 1990) |
| "An aspirin test has been performed in 100 asthma patients." | 3.68 | [Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma]. ( Didkovskiĭ, NA; Evseev, NG; Treskunov, VK; Zakharzhevskaia, TV, 1990) |
| "Nineteen asthmatic patients, 11 with and eight without aspirin (ASA) intolerance were studied in order to test possible platelet and coagulation system involvement in the pathogenesis of aspirin-induced bronchoconstriction (AIB)." | 3.67 | Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics. ( Bednarowicz, A; Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1987) |
| "The role of a commonly ingested food additive, the preservative sodium metabisulfite (MBS), and aspirin (ASA), in chronic asthma has been studied in 29 children." | 3.67 | Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma. ( Mellis, CM; Towns, SJ, 1984) |
| "Ketotifen administered prior to aspirin offered protection against bronchoconstriction in 13 of 14 patients with aspirin-sensitive asthma." | 3.66 | Inhibition by ketotifen of idiosyncratic reactions to aspirin. ( Czerniawska-Mysik, G; Kuklinski, P; Serwonska, M; Szczeklik, A, 1980) |
| "Nine patients with aspirin-induced bronchospasm were compared with age-matched normal controls to test the hypothesis that a defect in the beta-adrenergic system could lead to excessive dependence on prostaglandins to maintain bronchodilator function." | 3.66 | A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm. ( Conolly, ME; Fisher, HK; Hui, KK; Tashkin, DP; Wolfe, RN, 1982) |
| "The reported incidence of acute bronchospasm in patients with asthma who take aspirin varies from 2% to 28%, depending on the methods used to obtain data." | 3.66 | Analgesic-induced asthma. ( Seale, JP, 1983) |
| " Furthermore, pathogenesis, clinical picture, treatment and prophylaxis of the "Aspirin-induced asthma" are demonstrated." | 3.66 | [Drug-induced bronchospasm (author's transl)]. ( Strumeliev, S, 1978) |
| "Eleven patients with intrinsic asthma and aspirin sensitivity were challenged with intravenous hydrocortisone sodium succinate (Solu-Cortef; the Upjohn Co." | 3.66 | Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. ( Dajani, BM; Hamzeh, YS; Shubair, KS; Sliman, NA, 1981) |
| "Guacetisal was administered to a group of patients suffering from chronic asthmatic bronchitis." | 3.66 | [Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal]. ( Bande, G; Coghe, M; Meloni, M; Nonne, G, 1981) |
| "Evidence has been presented supporting the hypothesis that at least 2 different types of mechanisms may be involved in aspirin intolerance, one resulting in bronchospasm and the other producing urticaria/angioedema." | 3.65 | Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine. ( Pudupakkam, RK; Settipane, GA, 1975) |
| "Reports of drug-induced pulmonary disease from other countries are also reviewed." | 2.38 | Drug-induced pulmonary disease. ( Bryant, DH, 1992) |
| "Pretreatment with montelukast allowed only one patient to proceed through all challenge doses of ASA without any reactions." | 1.31 | Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics. ( Christiansen, SC; Mathison, DA; Simon, RA; Stevenson, DD, 2000) |
| "The inhalation challenge with lysine-aspirin (L-ASA) using the dosimeter method allows the construction of a dose-response curve and the quantitative estimation of airway responsiveness to the drug." | 1.28 | Aspirin-induced asthma and bronchial hyperresponsiveness. ( Cocco, G; Masi, C; Melillo, E; Melillo, G; Padovano, A, 1991) |
| " Desensitization, when essential, may be achieved for most drugs with graduated dosage schedules and maintained through continued administration of the drug." | 1.27 | Management of adverse drug reactions. ( Pennoyer, DS; Sheffer, AL, 1984) |
| "Pretreatment with aspirin (80 mg X kg -1 iv) did not prevent the bronchoconstriction caused by PAF-acether, and intravenous or intratracheal arachidonic acid caused no bronchial response." | 1.27 | Acute effects of intratracheal administration of platelet-activating factor in baboons. ( Arnoux, B; Benveniste, J; Denjean, A; Lockhart, A; Masse, R, 1983) |
| "In 97." | 1.26 | [Hypersensitivity to acetysal in bronchial asthma]. ( Kosturkov, G; Mileva, Zh; Staneva-Stoianova, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (61.70) | 18.7374 |
| 1990's | 16 (17.02) | 18.2507 |
| 2000's | 16 (17.02) | 29.6817 |
| 2010's | 4 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foong, NZE | 1 |
| Yii, ACA | 1 |
| Hsu, AAL | 1 |
| Lang, DM | 3 |
| Aronica, MA | 1 |
| Maierson, ES | 1 |
| Wang, XF | 1 |
| Vasas, DC | 1 |
| Hazen, SL | 1 |
| Morales, DR | 1 |
| Lipworth, BJ | 1 |
| Guthrie, B | 1 |
| Jackson, C | 1 |
| Donnan, PT | 1 |
| Santiago, VH | 1 |
| Muñoz-Cano, R | 1 |
| Bartra, J | 1 |
| Vennera, MC | 1 |
| Valero, A | 1 |
| Picado, C | 1 |
| Leunig, A | 1 |
| Braunschweig, F | 1 |
| Havel, M | 1 |
| Markmann, S | 1 |
| Kramer, M | 1 |
| Menz, G | 1 |
| Dahlberg, PE | 1 |
| Busse, WW | 1 |
| Pasaje, CF | 1 |
| Kim, JH | 1 |
| Park, BL | 1 |
| Cheong, HS | 1 |
| Park, TJ | 1 |
| Lee, JS | 1 |
| Kim, Y | 1 |
| Bae, JS | 1 |
| Kim, JM | 1 |
| Park, JS | 1 |
| Park, CS | 1 |
| Shin, HD | 1 |
| Volkman, JA | 1 |
| Pontikes, PJ | 1 |
| STRESEMANN, E | 1 |
| Celik, G | 1 |
| Paşaoğlu, G | 1 |
| Bavbek, S | 1 |
| Abadoğlu, O | 1 |
| Dursun, B | 1 |
| Mungan, D | 1 |
| Misirligil, Z | 1 |
| Cormican, LJ | 1 |
| Farooque, S | 1 |
| Altmann, DR | 1 |
| Lee, TH | 2 |
| Rozsasi, A | 1 |
| Blidaru, N | 1 |
| Rockemann, M | 1 |
| Santak, B | 1 |
| Polzehl, D | 1 |
| Keck, T | 1 |
| Sheth, A | 1 |
| Reddymasu, S | 1 |
| Jackson, R | 1 |
| Sirvent, AE | 1 |
| Fernández, I | 1 |
| Enríquez, R | 1 |
| Alvarez, JG | 1 |
| Santos Calle, F | 1 |
| Samper, J | 1 |
| Arenas, MD | 1 |
| Reyes, A | 1 |
| Teixeira, MZ | 1 |
| Wang, XS | 1 |
| Wu, AY | 1 |
| Leung, PS | 1 |
| Lau, HY | 1 |
| Szczeklik, A | 4 |
| Czerniawska-Mysik, G | 3 |
| Serwonska, M | 2 |
| Kuklinski, P | 2 |
| Wolfe, RN | 1 |
| Hui, KK | 1 |
| Conolly, ME | 1 |
| Tashkin, DP | 1 |
| Fisher, HK | 1 |
| Settipane, GA | 6 |
| Korzec, I | 1 |
| Seale, JP | 1 |
| Jones, DH | 1 |
| May, AG | 1 |
| Condemi, JJ | 1 |
| Sheffer, AL | 1 |
| Pennoyer, DS | 1 |
| Rossoni, G | 2 |
| Omini, C | 2 |
| Folco, GC | 2 |
| Vigano, T | 2 |
| Brunelli, G | 1 |
| Berti, F | 2 |
| Denjean, A | 1 |
| Arnoux, B | 1 |
| Masse, R | 1 |
| Lockhart, A | 1 |
| Benveniste, J | 2 |
| McFadden, ER | 1 |
| Towns, SJ | 1 |
| Mellis, CM | 1 |
| Ribon, A | 1 |
| Parikh, S | 1 |
| Vargaftig, BB | 2 |
| Lefort, J | 2 |
| Chignard, M | 2 |
| Wal, F | 1 |
| Crocker, JF | 1 |
| Ross, SR | 1 |
| Friedman, CJ | 1 |
| Lesnefsky, EJ | 1 |
| Szmidt, M | 3 |
| Grzelewska-Rzymowska, I | 3 |
| Rozniecki, J | 3 |
| Kowalski, ML | 2 |
| Rychlicka, I | 1 |
| Bande, G | 1 |
| Coghe, M | 1 |
| Meloni, M | 1 |
| Nonne, G | 1 |
| Dajani, BM | 1 |
| Sliman, NA | 1 |
| Shubair, KS | 1 |
| Hamzeh, YS | 1 |
| Butler, KD | 1 |
| Smith, JR | 1 |
| Carnovali, M | 1 |
| Ohnmeiss, E | 1 |
| Kosturkov, G | 1 |
| Staneva-Stoianova, M | 1 |
| Mileva, Zh | 1 |
| Settipane, RA | 1 |
| Constantine, HP | 1 |
| Dahl, R | 1 |
| Nizankowska, E | 2 |
| Mandelli, V | 1 |
| Salberg, DJ | 1 |
| Simon, MR | 1 |
| Novak-Jankovic, V | 1 |
| Paver-Erzen, V | 1 |
| Podboj, J | 1 |
| Judson, MA | 1 |
| Sperl, PL | 1 |
| Yoshikawa, T | 1 |
| Iida, Y | 1 |
| Horiuchi, I | 1 |
| Inaba, S | 1 |
| Terai, T | 1 |
| Rothe, T | 1 |
| Achermann, R | 1 |
| Hug, J | 1 |
| Karrer, W | 1 |
| Chen, AH | 1 |
| Bennett, CR | 1 |
| Sturtevant, J | 1 |
| Singh, RK | 1 |
| Bhattacharya, SK | 1 |
| Acharya, SB | 1 |
| Stevenson, DD | 3 |
| Simon, RA | 1 |
| Mathison, DA | 1 |
| Christiansen, SC | 2 |
| Obase, Y | 1 |
| Shimoda, T | 1 |
| Tomari, S | 1 |
| Mitsuta, K | 1 |
| Fukushima, C | 1 |
| Kawano, T | 1 |
| Matsuse, H | 1 |
| Kohno, S | 1 |
| Kounis, NG | 1 |
| Wuethrich, B | 1 |
| Radielovic, P | 1 |
| Debelic, M | 1 |
| Wüthrich, B | 1 |
| Strumeliev, S | 1 |
| Kuś, J | 1 |
| Schachter, EN | 1 |
| Kreisman, H | 1 |
| Bouhuys, A | 1 |
| Gillett, DG | 1 |
| Ford, GT | 1 |
| Martelli, NA | 1 |
| Usandivaras, G | 1 |
| Weber, RW | 1 |
| Hoffman, M | 1 |
| Raine, DA | 1 |
| Nelson, HS | 1 |
| Basomba, A | 1 |
| Romar, A | 1 |
| Peláez, A | 1 |
| Villalmanzo, IG | 1 |
| Campos, A | 1 |
| Arroyave, CM | 1 |
| Vaughan, JH | 1 |
| Tan, EM | 1 |
| Holmes, IB | 1 |
| Pudupakkam, RK | 1 |
| García Gama, X | 1 |
| Juergens, UR | 1 |
| Zuraw, BL | 1 |
| Bryant, DH | 1 |
| Leung, R | 1 |
| Plomley, R | 1 |
| Czarny, D | 1 |
| McDeed-Breault, C | 1 |
| Melillo, G | 1 |
| Padovano, A | 1 |
| Masi, C | 1 |
| Melillo, E | 1 |
| Cocco, G | 1 |
| Christie, PE | 1 |
| Tagari, P | 1 |
| Ford-Hutchinson, AW | 1 |
| Charlesson, S | 1 |
| Chee, P | 1 |
| Arm, JP | 1 |
| Dworski, R | 1 |
| Soja, J | 1 |
| Meeker, DP | 1 |
| Wiedemann, HP | 1 |
| Suenaga, N | 1 |
| Nakamura, H | 1 |
| Shiratusuki, N | 1 |
| Hirano, T | 1 |
| Uyama, O | 1 |
| Kitada, O | 1 |
| Sugita, M | 1 |
| Treskunov, VK | 1 |
| Didkovskiĭ, NA | 1 |
| Zakharzhevskaia, TV | 1 |
| Evseev, NG | 1 |
| Lupinetti, MD | 1 |
| Sheller, JR | 1 |
| Catella, F | 1 |
| Fitzgerald, GA | 1 |
| Grzegorczyk, J | 1 |
| Bednarowicz, A | 1 |
| Rosenblatt, J | 1 |
| Sharp, A | 1 |
| Vane, JR | 1 |
| Pascaud, XB | 1 |
| Devys, MM | 1 |
| Errard, DJ | 1 |
| Bodammer, G | 1 |
| Marquardt, H | 1 |
| Parker, CW | 1 |
| Snider, DE | 1 |
| Chafee, FH | 1 |
| Klein, DE | 1 |
| Fein, BT | 1 |
| Shevchenko, AI | 1 |
| Barron, DI | 1 |
| Copley, AR | 1 |
| Vallance, DK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Placebo Controlled, Double-Blind Investigation of the Therapeutic Utility of Xolair (Omalizumab) for Attenuating Aspirin Induced Bronchospasm in Patients With Aspirin Exacerbated Respiratory Disease (AERD) Undergoing Aspirin Desentization[NCT00555971] | Phase 4 | 16 participants (Actual) | Interventional | 2006-05-31 | Completed | ||
| Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass (the OPTIMAL Study)[NCT03782350] | Phase 4 | 3,079 participants (Actual) | Interventional | 2018-12-26 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Measurements of urinary LTE4 in association with aspirin desensitization, comparing subjects randomized to placebo with subjects randomized to omalizumab, with study drug administered for 16 weeks. Measurements were compared for respiratory reaction in placebo subjects who exhibited either upper or lower airway reaction and after 100 mg aspirin challenge dose in omalizumab subjects who were non-reactors. For this analysis, the two omalizumab subjects who had respiratory reaction were not included. (NCT00555971)
Timeframe: Approximately 24 weeks
| Intervention | pg/mg creatinine units (Mean) |
|---|---|
| Placebo | 17489 |
| Omalizumab | 1852 |
Lack of Respiratory reaction during aspirin desensitization, including Spirometry (FEV1) testing, to assess the efficacy of Xolair on attenuating aspirin induced bronchospasm in patients with AERD. (NCT00555971)
Timeframe: 24 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo | 0 |
| Omalizumab | 5 |
15 reviews available for aspirin and Bronchial Spasm
| Article | Year |
|---|---|
Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Clinical Trial | 2014 |
Is intrinsic asthma synonymous with infection?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Female; Humans; Lung; Mal | 2009 |
Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Cl | 2002 |
Blocking aspirin-induced bronchospasm.
Topics: Administration, Oral; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchial Spasm; Drug Administration S | 2005 |
Worsening of asthma with systemic corticosteroids. A case report and review of literature.
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Glucocorticoids; Humans; Male; Methylpredni | 2006 |
Aspirin and allergic diseases: a review.
Topics: Aspirin; Asthma; Bronchial Spasm; Cross Reactions; Desensitization, Immunologic; Drug Hypersensitivi | 1983 |
[Bronchial asthma caused by aspirin hypersensitivity (pathomechanism and diagnostic and therapeutic problems)].
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans | 1984 |
Adverse reactions of aspirin and related drugs.
Topics: Aspirin; Bronchial Spasm; Drug Hypersensitivity; Humans; Ibuprofen; Indomethacin; Prostaglandins; Ur | 1981 |
Role of the metabolites of arachidonate in platelet-dependent and independent experimental bronchoconstriction.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Blood Platelets; Bronchial Spasm; Car | 1981 |
Tartrazine sensitivity and aspirin intolerance.
Topics: Aspirin; Azo Compounds; Bronchial Spasm; Cross Reactions; Drug Hypersensitivity; Humans; Rhinitis; T | 1977 |
[Asthma and aspirin intolerance].
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Metabolism, Inborn Errors; Nasal Po | 1978 |
Drug-induced lung disease.
Topics: Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Aspirin; Bronchial Spasm; Eosinophilia; Human | 1978 |
Drug-induced pulmonary disease.
Topics: Adrenergic beta-Antagonists; Adverse Drug Reaction Reporting Systems; Aerosols; Amiodarone; Angioten | 1992 |
Drug-induced bronchospasm.
Topics: Aerosols; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bronchi; Bronchial Spasm; Drug Hypersen | 1990 |
Prostaglandins and asthma.
Topics: Aerosols; Airway Resistance; Animals; Aspirin; Asthma; Atropine; Bronchi; Bronchial Spasm; Cyclic AM | 1973 |
11 trials available for aspirin and Bronchial Spasm
| Article | Year |
|---|---|
Omalizumab can inhibit respiratory reaction during aspirin desensitization.
Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma, Aspirin-Induced; Biomarkers; Bronchial Spasm; Desensi | 2018 |
Tolerability of selective cyclooxygenase inhibitor, celecoxib, in patients with analgesic intolerance.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchial Spasm; Celecoxib; Cy | 2005 |
Sodium salicylate and aspirin disease.
Topics: Aspirin; Bronchial Spasm; Diet; Drug Hypersensitivity; Humans; Peak Expiratory Flow Rate; Sodium Sal | 1980 |
A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome.
Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, I | 1995 |
Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics.
Topics: Adult; Aged; alpha 1-Antitrypsin; Aspirin; Asthma; Benzoates; Bronchial Spasm; Complement C1 Inactiv | 1979 |
Prostaglandin-synthesis inhibition and exercise bronchospasm.
Topics: Aspirin; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; Indomethacin; Physi | 1978 |
Inhibition of aspirin-induced bronchoconstriction by sodium cromoglycate inhalation.
Topics: Adolescent; Adult; Aspirin; Bronchial Spasm; Clinical Trials as Topic; Cromolyn Sodium; Drug Hyperse | 1977 |
Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics.
Topics: Adolescent; Adult; Aspirin; Asthma; Azo Compounds; Benzoates; Bronchial Spasm; Coloring Agents; Doub | 1979 |
Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; F | 1991 |
Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Choline; Double-Bl | 1990 |
Thromboxane biosynthesis in allergen-induced bronchospasm. Evidence for platelet activation.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Allergens; Aspirin; Blood Platelets; Bronchial Spasm; Clinical | 1989 |
68 other studies available for aspirin and Bronchial Spasm
| Article | Year |
|---|---|
Severe life-threatening asthma precipitated by a topical nonsteroidal anti-inflammatory drug.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adult; Albuterol; Aspirin; Asthma, Aspirin-Induc | 2018 |
Asthmatic reaction induced by celecoxib in a patient with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Cyclooxygenase Inhibitors; Drug Hypersensitivity | 2009 |
[Chronic rhinosinusitis and aspirin intolerance].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Desensitization, I | 2009 |
Association of the variants in AGT gene with modified drug response in Korean aspirin-intolerant asthma patients.
Topics: Acetates; Adolescent; Adult; Aged; Algorithms; Angiotensinogen; Anti-Asthmatic Agents; Asian People; | 2011 |
[THE EFFECT OF BRADYKININ AEROSOL ON THE RESPIRATION OF HUMANS AND GUINEA PIGS AND THE INFLUENCE OF VARIOUS SUBSTANCE ON EXPERIMENTAL BRADYKININ BRONCHOSPASM].
Topics: Aerosols; Aminopyrine; Animals; Aspirin; Asthma; Atropine; Bradykinin; Bronchial Spasm; Guinea Pigs; | 1963 |
Improvements in an oral aspirin challenge protocol for the diagnosis of aspirin hypersensitivity.
Topics: Administration, Oral; Adult; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2005 |
[Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?].
Topics: Acetaminophen; Adult; Aged; Algorithms; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal | 2006 |
[Hypersensitivity reaction to systemic corticosteroids in a hemodialysis patients].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Aspirin; Asthma; Bronchial Spasm; Desensitization, Immu | 2006 |
Bronchodilators, fatal asthma, rebound effect and similitude.
Topics: Antidepressive Agents; Aspirin; Asthma; Bronchial Spasm; Bronchodilator Agents; Evidence-Based Medic | 2007 |
PGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Aspirin; Bronchial Spasm | 2007 |
Inhibition by ketotifen of idiosyncratic reactions to aspirin.
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; Histamine H1 Antago | 1980 |
A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm.
Topics: Adult; Aged; Airway Obstruction; Alprostadil; Aspirin; Bronchial Spasm; Female; Forced Expiratory Vo | 1982 |
Analgesic-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma | 1983 |
HLA DR typing of aspirin sensitive asthmatics.
Topics: Aspirin; Asthma; Bronchial Spasm; Disease Susceptibility; Drug Hypersensitivity; Female; Genes, MHC | 1984 |
Management of adverse drug reactions.
Topics: Anaphylaxis; Antineoplastic Agents; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Drug-Related Si | 1984 |
Bronchodilating activity of mequitazine.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Aspirin; Atropine; Blood Pressure; Bronchial | 1984 |
Acute effects of intratracheal administration of platelet-activating factor in baboons.
Topics: Anesthesia, Local; Animals; Aspirin; Atropine; Bronchi; Bronchial Spasm; Lidocaine; Papio; Platelet | 1983 |
Pathogenesis of asthma.
Topics: Adult; Air Pollution; Allergens; Animals; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Bronch | 1984 |
Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma.
Topics: Adolescent; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Child; Child, Preschool; | 1984 |
Drug-induced asthma: a review.
Topics: Alfaxalone Alfadolone Mixture; Aspirin; Asthma; Azo Compounds; Bronchial Spasm; Coloring Agents; Con | 1980 |
Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Epoprostenol; In Vitro Techniques; Lysophosphati | 1980 |
Commentary: acetylsalicylic acid or aspirin?
Topics: Adult; Aspirin; Bronchial Spasm; Canada; Drug Hypersensitivity; Female; Humans; Prostaglandins E; Ri | 1982 |
Near fatal bronchospasm induced by zomepirac sodium.
Topics: Adult; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Humans; Male; Pyrroles; Tolmetin | 1982 |
[Venous blood histamine level during aspirin-induced bronchial spasm].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forearm; Histami | 1980 |
[Clinico-functional data concerning chronic asthmatic bronchitis patients treated wih guacetisal].
Topics: Adult; Aged; Aspirin; Bronchial Spasm; Bronchitis; Cough; Dyspnea; Female; Humans; Male; Middle Aged | 1981 |
Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Dexamethasone; Female; Forced Expiratory Volume; Humans; Hy | 1981 |
Mechanisms of Forssman-induced bronchospasm and their inhibition.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Complement System Proteins; Forssman Antigen; Gu | 1981 |
[Asthma caused by inhibitors of prostaglandin synthesis].
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Bronchial Spasm; Humans; Prostaglandin Antagonists | 1981 |
[Hypersensitivity to acetysal in bronchial asthma].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Spasm; Chronic Disease; Drug Hypersensitivity; F | 1980 |
Aspirin intolerance and recurrent urticaria in normal adults and children. Epidemiology and review.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Bronchial Spasm; Child; Child, Preschool; Drug Hypers | 1980 |
Sulfinpyrazone and aspirin-induced asthma.
Topics: Anaphylaxis; Aspirin; Asthma; Bronchial Spasm; Dipyrone; Drug Hypersensitivity; Humans; Sulfinpyrazo | 1980 |
Inhibition of idiosyncratic reactions to aspirin by ketotifen.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Ketotifen; Piperidines; Thio | 1980 |
Bronchoconstriction by histamine and bradykinin in guinea pigs: relationship to thromboxane A2 generation and the effect of aspirin.
Topics: Acetylcholine; Animals; Aspirin; Blood Pressure; Bradykinin; Bronchial Spasm; Dose-Response Relation | 1980 |
Severe asthma induced by naproxen--a case report and review of the literature.
Topics: Acute Disease; Arthritis; Aspirin; Asthma; Bronchial Spasm; Humans; Male; Middle Aged; Naproxen; Pro | 1980 |
Status asthmaticus with acute decompensation with therapy in a 27-year-old woman.
Topics: Acute Disease; Adult; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Infusions, In | 1995 |
[Bronchospasms caused by intravenous hydrocortisone sodium hemisuccinate (Solu-Cortef) in an aspirin-sensitive asthmatic patient].
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Hydrocortisone; Infusions, I | 1993 |
Incomplete aspirin desensitization in an aspirin-sensitive asthmatic.
Topics: Aspirin; Asthma; Bronchial Spasm; Desensitization, Immunologic; Drug Tolerance; Female; Humans; Midd | 1996 |
Ketorolac-induced bronchospasm in an aspirin-intolerant patient.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Contraindications; | 1994 |
NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority.
Topics: Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Chroni | 1999 |
Antileukotriene agents and aspirin-sensitive asthma: are we removing the second bassoonist or skating to where the puck is gonna be?
Topics: Aspirin; Asthma; Bronchial Spasm; Humans; Hydroxyurea; Leukotriene Antagonists; Therapeutic Equivale | 2000 |
Pharmacological activity of Abies pindrow.
Topics: Animals; Aspirin; Bronchial Spasm; Cycadopsida; Female; Guinea Pigs; Histamine; Histamine Antagonist | 2000 |
Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics.
Topics: Acetates; Adult; Aged; Aspirin; Asthma; Bronchial Spasm; Cyclopropanes; Female; Forced Expiratory Vo | 2000 |
Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstriction; Chromones | 2001 |
A review: drug-induced bronchospasm.
Topics: Analgesics; Aspirin; Bronchial Spasm; Cyclic AMP; Drug Hypersensitivity; Histamine; Histamine H1 Ant | 1976 |
The protective effect of a new oral anti-asthma agent (ketotifen, HC 20--511) against experimentally induced bronchospasm (5 different models).
Topics: Acetylcholine; Aerosols; Antigens; Aspirin; Benzoates; Bronchial Spasm; Double-Blind Method; Histami | 1978 |
[Drug-induced bronchospasm (author's transl)].
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; H | 1978 |
The effect of sodium cromoglycate in preventing aspirin induced bronchospasm.
Topics: Adult; Airway Obstruction; Aspirin; Bronchial Spasm; Cromolyn Sodium; Drug Evaluation; Drug Hypersen | 1976 |
Plasma complement changes during bronchospasm provoked in asthmatic patients.
Topics: Aerosols; Antigens; Aspirin; Asthma; Bronchial Spasm; Complement C1; Complement C3; Complement C4; C | 1977 |
A comparison of the effect of proquazone, a new non-steroidal antiinflammatory compound, compound, and acetylsalicylic acid on blood platelet function in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Bronchial Spasm; Collagen; Guinea Pigs; | 1977 |
Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine.
Topics: Angioedema; Aspirin; Asthma; Azo Compounds; Benzenesulfonates; Bronchial Spasm; Cross Reactions; Dru | 1975 |
[Intolerance to aspirin].
Topics: Adult; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Male; | 1976 |
Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge.
Topics: Administration, Oral; Adult; Arachidonic Acid; Aspirin; Asthma; Bronchial Spasm; Calcimycin; Eicosan | 1992 |
Paracetamol anaphylaxis.
Topics: Acetaminophen; Anaphylaxis; Angioedema; Aspirin; Bronchial Spasm; Cross Reactions; Humans; Hypotensi | 1992 |
Toradol caution in the aspirin-sensitive.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchial Spasm; Cross Reactions; Drug Combination | 1992 |
Aspirin-induced asthma and bronchial hyperresponsiveness.
Topics: Adolescent; Adult; Airway Resistance; Angioedema; Aspirin; Asthma; Bronchial Hyperreactivity; Bronch | 1991 |
[Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient].
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Hydrocortisone | 1990 |
[Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchi; Bronchial Spasm; Bronchoconstrictor Agents; Bronc | 1990 |
[Chemotactic activity of serum neutrophils during aspirin-induced bronchial spasm].
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chemotaxis, Leukocyte; Drug Hy | 1987 |
Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Blood Coagulation; Blood Platelets; Bronchial Provocation Tests; Bronchial S | 1987 |
Upper airway angio-oedema.
Topics: Angioedema; Aspirin; Bronchial Spasm; Child; Humans; Male | 1985 |
Mediators of the anaphylactic reaction.
Topics: Anaphylaxis; Animals; Aorta; Aspirin; Bronchial Spasm; Guinea Pigs; Histamine Release; Immunity, Cel | 1971 |
The antiulcer and autonomic pharmacology of pyridyl-2-thioacetamide (CMN 131).
Topics: Acetamides; Animals; Aspirin; Autonomic Nervous System; Bronchial Spasm; Cats; Dogs; Ganglia, Autono | 1974 |
[Studies on the mechanism of the respiratory effects of anaphylatoxin].
Topics: Animals; Aspirin; Atropine; Bronchial Diseases; Bronchial Spasm; Constriction; Guinea Pigs; Histamin | 1968 |
[On the problem of pathogenesis of vagus reflex bradykinin tachypnea].
Topics: Animals; Aspirin; Bradykinin; Bronchial Spasm; Dyspnea; Guinea Pigs; Isoproterenol; Lung; Papaverine | 1966 |
Aspirin intolerance. II. A prospective study in an atopic and normal population.
Topics: Allergens; Angioedema; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Male | 1974 |
Aspirin shock associated with asthma and nasal polyps.
Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Spasm; Child; Child, Preschool; Drug Hypersensitivity; | 1971 |
[The effect of antipyretics on experimental bronchospasm].
Topics: Aminopyrine; Animals; Aspirin; Bronchial Spasm; Cats; Sodium Salicylate | 1969 |
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial | 1968 |