Page last updated: 2024-10-23

aspirin and Brain Swelling

aspirin has been researched along with Brain Swelling in 31 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
" Fever always occurred before their admission and aspirin (n = 12) or acetaminophen (n = 7) was prescribed."3.71[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years]. ( Brivet, M; Chevret, L; Debray, D; Devictor, D; Durand, P; Fabre, M; Thabet, F, 2002)
"The effects of aminazin and aspirin on brain injuries in animals with immunological hypersensitivity of the body were studied."3.66[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs]. ( Sukhorukova, LI, 1981)
"We provided optimal treatment of severe hyperammonemia (>500 µmol/L) and cerebral edema, including high doses of arginine chloride, sodium benzoate, hemodialysis, mild hypothermia, and supportive care."1.62Reye Syndrome with Severe Hyperammonemia and a Good Neurological Outcome. ( Battelino, T; Bratina, N; Groselj, U; Herga, P; Klemenčič, S; Osredkar, D; Pribožič, L; Rajtar Osredkar, S; Repič Lampret, B; Vidmar, I; Žerjav Tanšek, M, 2021)
"Previously influenza with high temperature, headache and vomiting had occurred and been treated with acetylsalicylic acid for some days."1.38[21-year-old woman with Reye's syndrome after influenza]. ( Böhm, M; Kaplan, BT; Link, A, 2012)
"Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion."1.33Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005)
"Aspirin treatment improved survival ratio and stroke index, and decreased ischemically injured cell numbers in cortex."1.31Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia. ( Hosomi, N; Kohno, M; Mizushige, K; Ohyama, H; Takahashi, T, 2001)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's6 (19.35)18.2507
2000's8 (25.81)29.6817
2010's7 (22.58)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Wu, J1
Ling, J1
Wang, X1
Li, T1
Liu, J1
Lai, Y1
Ji, H1
Peng, S1
Tian, J1
Zhang, Y1
Pribožič, L1
Žerjav Tanšek, M1
Herga, P1
Osredkar, D1
Rajtar Osredkar, S1
Vidmar, I1
Repič Lampret, B1
Klemenčič, S1
Bratina, N1
Battelino, T1
Groselj, U1
Rahmani, MR1
Shamsizadeh, A1
Moghadam-Ahmadi, A1
Kaeidi, A1
Allahtavakoli, M1
Liptai, Z1
Ivády, B1
Barsi, P1
Várallyay, G1
Rudas, G1
Fogarasi, A1
Selves, A1
Ruiz, S1
Crognier, L1
Conil, JM1
Bonneville, F1
Georges, B1
Dupuy, M1
Fourcade, O1
Geeraerts, T1
Lopez, JI1
Holdridge, A1
Mendizabal, JE1
Bhatt, LK1
Addepalli, V1
Link, A1
Kaplan, BT1
Böhm, M1
Zunker, P1
Golombeck, K1
Brossmann, J1
Georgiadis, D2
Deuschl, G1
Michel, P1
Bogousslavsky, J1
Baumgartner, RW1
Xia, JX1
Wang, YX1
Shinohara, Y1
Lee, JH1
Park, SY1
Lee, WS1
Hong, KW1
Husain, E1
Hoque, E1
Daugherty, CC1
McAdams, AJ2
Partin, JS1
Dove, DJ1
Jones, T1
Sukhorukova, LI1
Imura, Y1
Kiyota, Y1
Nagai, Y1
Nishikawa, K1
Terashita, Z1
Cole, DJ1
Schell, RM1
Drummond, JC1
Reynolds, L1
Bruno, A1
Yamamoto, N1
Yokota, K1
Yamashita, A1
Oda, M1
Morgan, MK1
Sekhon, LH1
Finfer, S1
Grinnell, V1
Yamaguchi, T1
Ohyama, H1
Hosomi, N1
Takahashi, T1
Mizushige, K1
Kohno, M1
Thabet, F1
Durand, P1
Chevret, L1
Fabre, M1
Debray, D1
Brivet, M1
Devictor, D1
Debons, AF1
Krimsky, I1
From, A1
Siclari, E1
Maayan, ML1
Fani, K1
Jimenez, FA1
Bray, PF1
Gardiner, AY1
Warren, RD1
Meyers, DS1
Pape, BA1
Maher, JF1
Greenhouse, AH1
Strauss, RG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823]50 participants (Anticipated)Observational2019-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for aspirin and Brain Swelling

ArticleYear
Altitude headache.
    Current pain and headache reports, 2013, Volume: 17, Issue:12

    Topics: Acute Disease; Adaptation, Physiological; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Asp

2013
[Treatment of acute stroke -- an overview].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9

    Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cereb

2003
[Clinical guidelines for stroke].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Nov-10, Volume: 93, Issue:11

    Topics: Anticoagulants; Antipyrine; Arginine; Aspirin; Brain Edema; Edaravone; Fibrinolytic Agents; Free Rad

2004
[Current status and future prospects in the treatment of acute-phase cerebral infarction].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: Acute-Phase Reaction; Aspirin; Brain Edema; Calcium Channel Blockers; Cerebral Infarction; Fibrinoly

1999

Trials

1 trial available for aspirin and Brain Swelling

ArticleYear
Post-partum cerebral angiopathy: repetitive TCD, MRI, MRA, and EEG examinations.
    Neurological research, 2002, Volume: 24, Issue:6

    Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Brain Ed

2002

Other Studies

26 other studies available for aspirin and Brain Swelling

ArticleYear
Discovery of a potential anti-ischemic stroke agent: 3-pentylbenzo[c]thiophen-1(3H)-one.
    Journal of medicinal chemistry, 2012, Aug-23, Volume: 55, Issue:16

    Topics: Animals; Antioxidants; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Fibrinolytic Agents; Fr

2012
Reye Syndrome with Severe Hyperammonemia and a Good Neurological Outcome.
    The American journal of case reports, 2021, Oct-11, Volume: 22

    Topics: Aspirin; Brain Edema; Child, Preschool; Humans; Hyperammonemia; Liver Failure, Acute; Male; Reye Syn

2021
Monoacylglycerol lipase inhibitor, JZL-184, confers neuroprotection in the mice middle cerebral artery occlusion model of stroke.
    Life sciences, 2018, Apr-01, Volume: 198

    Topics: Animals; Aspirin; Behavior, Animal; Benzodioxoles; Brain; Brain Edema; Brain Ischemia; Disease Model

2018
Mild encephalitis/encephalopathy with a reversible splenial lesion in children.
    Ideggyogyaszati szemle, 2013, Jan-30, Volume: 66, Issue:1-2

    Topics: Adolescent; Anti-Inflammatory Agents; Antipyretics; Aspirin; Brain; Brain Edema; Child; Corpus Callo

2013
[Aspirin and its danger: Reye syndrome in young adult].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:11

    Topics: Acyclovir; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Aspirin; Brain Edema; Coma; De

2013
Potentiation of aspirin-induced cerebroprotection by minocycline: a therapeutic approach to attenuate exacerbation of transient focal cerebral ischaemia.
    Diabetes & vascular disease research, 2012, Volume: 9, Issue:1

    Topics: Animals; Aspirin; Blood Glucose; Blood-Brain Barrier; Body Weight; Brain; Brain Edema; Capillary Per

2012
[21-year-old woman with Reye's syndrome after influenza].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:38

    Topics: Ammonia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Diagnosis, Differential; Ele

2012
[Oral aspirin caused Reye's syndrome in a child].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2004, Volume: 42, Issue:4

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Child; Coma; Fe

2004
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats.
    Neurological research, 2005, Volume: 27, Issue:5

    Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede

2005
Meningoencephalitis as a presentation of Kawasaki disease.
    Journal of child neurology, 2006, Volume: 21, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Brain Edema; Cerebral Arteries; Child; Diag

2006
Aspirin and Reye's syndrome.
    Lancet (London, England), 1983, Jul-09, Volume: 2, Issue:8341

    Topics: Acute Disease; Adolescent; Aspirin; Brain Edema; Child; Child, Preschool; Female; Humans; Infant; In

1983
Delayed coma associated with salicylate intoxication.
    The Journal of pediatrics, 1982, Volume: 100, Issue:3

    Topics: Aspirin; Brain Edema; Child, Preschool; Coma; Female; Humans; Infant; Mannitol; Salicylates; Time Fa

1982
[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Animals; Aspirin; Autoimmune Diseases; Brain; Brain Edema; Brain Injuries; Chinchilla; Chlorpromazin

1981
Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model.
    Thrombosis research, 1995, Jul-01, Volume: 79, Issue:1

    Topics: Animals; Aspirin; Brain Chemistry; Brain Edema; Cerebral Arteries; Cerebral Infarction; Drug Evaluat

1995
Focal cerebral ischemia in rats. Effect of hypervolemic hemodilution with diaspirin cross-linked hemoglobin versus albumin on brain injury and edema.
    Anesthesiology, 1993, Volume: 78, Issue:2

    Topics: Albumins; Animals; Aspirin; Brain Edema; Brain Injuries; Brain Ischemia; Cross-Linking Reagents; Hem

1993
Ischemic stroke, Part 2: Optimal treatment and prevention.
    Geriatrics, 1993, Volume: 48, Issue:3

    Topics: Aged; Aspirin; Brain Edema; Brain Ischemia; Cerebral Infarction; Heparin; Humans; Recurrence; Risk F

1993
Effect of KBT-3022, a new cyclooxygenase inhibitor, on experimental brain edema in vitro and in vivo.
    European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3

    Topics: Animals; Arachidonic Acid; Aspirin; Brain; Brain Edema; Brain Ischemia; Cyclooxygenase Inhibitors; G

1996
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
    Journal of neurosurgery, 1999, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp

1999
Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia.
    Brain research, 2001, Jun-01, Volume: 902, Issue:2

    Topics: Animals; Antithrombins; Arginine; Aspirin; Blood Pressure; Brain Edema; Cerebrovascular Circulation;

2001
[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Child; Child, Preschoo

2002
Action of gold thioglucose on pericapillary structures in the ventromedial hypothalamus.
    The Journal of pathology, 1979, Volume: 129, Issue:2

    Topics: Animals; Aspirin; Aurothioglucose; Blood-Brain Barrier; Brain Edema; Dose-Response Relationship, Dru

1979
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23--1977.
    The New England journal of medicine, 1977, Jun-09, Volume: 296, Issue:23

    Topics: Acetaminophen; Acute Disease; Adolescent; Arthritis, Juvenile; Aspirin; Brain Death; Brain Edema; Ch

1977
Salicylism and severe brain edema.
    The New England journal of medicine, 1977, Dec-01, Volume: 297, Issue:22

    Topics: Arthritis, Juvenile; Aspirin; Brain Edema; Child, Preschool; Humans; Male

1977
Fatal overdose of propoxyphene napsylate and aspirin. A case report with pathologic and toxicologic study.
    JAMA, 1974, Oct-14, Volume: 230, Issue:2

    Topics: Acute Disease; Adult; Aspirin; Autopsy; Brain Edema; Bronchitis; Dextropropoxyphene; Drug Combinatio

1974
Transient ischemic attack: an early warning system for stroke?
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Aged; Angiography; Anticoagulants; Aspirin; Blood Pressure; Brain Edema; Cerebrovascular Disorders;

1973
Arthritis, aspirin, and coma.
    The Journal of pediatrics, 1970, Volume: 77, Issue:1

    Topics: Arthritis, Juvenile; Aspirin; Brain Edema; Chemical and Drug Induced Liver Injury; Child, Preschool;

1970