aspirin has been researched along with Brain Disorders in 37 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute hepatic decompensation and encephalopathy may occur as a consequence of aspirin hepatoxicity in JRA and justify sequential observations of liver function tests and salicylate levels in such patients." | 5.26 | Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. ( Crain, JD; Gelfand, EW; Grand, RJ; Ulshen, MH, 1978) |
| " Aspirin effectively abolished SPA in 50 patients and relieved the clinical symptoms of patients with recurrent complaints of transient blindness and paraesthesia." | 3.66 | Spontaneous platelet aggregation in cerebrovascular disease. ( Jenkins, CS; Oosterhuis, H; Prenger, D; ten Cate, JW; Vos, J, 1978) |
| "Hemorrhagic stroke is the most common type of obstetric stroke." | 2.72 | Stroke in Pregnancy: A Multidisciplinary Approach. ( Camargo, EC; Singhal, AB, 2021) |
| "Treatment with aspirin and ceftriaxone followed by trimethoprim-sulfamethoxazole resulted in a good neurological recovery and complete remission of the malabsorption syndrome." | 1.33 | A patient with cerebral Whipple's disease and a stroke-like syndrome. ( De Simone, C; Famularo, G; Minisola, G, 2005) |
| "Polyarteritis nodosa is a difficult condition to diagnose in a child and can cause brainstem lesions." | 1.32 | Ocular tilt reaction due to a mesencephalic lesion in juvenile polyarteritis nodosa. ( Chong, WK; Dillon, MJ; Elston, J; Harris, CM; Ragge, NK; Taylor, DS, 2003) |
| " There was no significant difference in the AUC-value between the two routes of administration, but a slower rate of absorption with no clear peak effect was found after rectal administration." | 1.26 | Bioavailability of rectal aspirin in neurosurgical patients. ( Kanto, J; Klossner, J; Mäntylä, R; Yrjänä, T, 1981) |
| "Acute hepatic decompensation and encephalopathy may occur as a consequence of aspirin hepatoxicity in JRA and justify sequential observations of liver function tests and salicylate levels in such patients." | 1.26 | Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. ( Crain, JD; Gelfand, EW; Grand, RJ; Ulshen, MH, 1978) |
| "Hallucinations were either unformed (for example, bright lights, straight lines) or highly formed (for example, faces), in which case they were invariably recognized by the patient as inappropriate." | 1.25 | Cerebral disorders of vision in systemic lupus erythematosus. ( Brandt, KD; Cohen, AS; Lessell, S, 1975) |
| "A case of hepatotoxicity and encephalopathy (Reye's syndrome?) associated with salicylate therapy is presented and the aetiology of this syndrome is discussed." | 1.25 | Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy. ( Koivikko, A; Mäkelä, AL; Sillanpää, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (56.76) | 18.7374 |
| 1990's | 4 (10.81) | 18.2507 |
| 2000's | 7 (18.92) | 29.6817 |
| 2010's | 3 (8.11) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Chen, Y | 1 |
| Liu, J | 1 |
| Mai, X | 1 |
| Jing, S | 1 |
| Camargo, EC | 1 |
| Singhal, AB | 1 |
| Pandya, DJ | 1 |
| Fitzsimmons, BF | 1 |
| Wolfe, TJ | 1 |
| Hussain, SI | 1 |
| Lynch, JR | 1 |
| Ortega-Gutierrez, S | 1 |
| Zaidat, OO | 1 |
| Alkan, O | 1 |
| Yildirim, T | 1 |
| Kizilkiliç, O | 1 |
| Tan, M | 1 |
| Cekinmez, M | 1 |
| Hughes, GR | 1 |
| Liu, W | 1 |
| Liu, R | 1 |
| Sun, W | 1 |
| Peng, Q | 1 |
| Zhang, W | 1 |
| Xu, E | 1 |
| Cheng, Y | 1 |
| Ding, M | 1 |
| Li, Y | 1 |
| Hong, Z | 1 |
| Wu, J | 1 |
| Zeng, J | 1 |
| Yao, C | 1 |
| Huang, Y | 1 |
| Ragge, NK | 1 |
| Harris, CM | 1 |
| Dillon, MJ | 1 |
| Chong, WK | 1 |
| Elston, J | 1 |
| Taylor, DS | 1 |
| MITSUSE, J | 1 |
| MORIYAMA, K | 1 |
| GILES, HM | 1 |
| Farray, D | 1 |
| Carman, TL | 1 |
| Fernandez, BB | 1 |
| Famularo, G | 1 |
| Minisola, G | 1 |
| De Simone, C | 1 |
| Collombet, JM | 1 |
| Baubichon, D | 1 |
| Masqueliez, C | 1 |
| Bernabé, D | 1 |
| Four, E | 1 |
| Burckhart, MF | 1 |
| Lallement, G | 1 |
| Kleffner, I | 1 |
| Ringelstein, EB | 1 |
| Stupp, N | 1 |
| Niederstadt, TU | 1 |
| Young, P | 1 |
| Ducros, A | 1 |
| Ducobu, J | 1 |
| Dupont, P | 1 |
| Viinikka, L | 1 |
| Dewanjee, MK | 1 |
| Fuster, V | 1 |
| Rao, SA | 1 |
| Forshaw, PL | 1 |
| Kaye, MP | 1 |
| Kanto, J | 1 |
| Klossner, J | 1 |
| Mäntylä, R | 1 |
| Yrjänä, T | 1 |
| Yatsu, FM | 1 |
| Enserink, M | 1 |
| Morgan, MK | 1 |
| Sekhon, LH | 1 |
| Finfer, S | 1 |
| Grinnell, V | 1 |
| McDonald, L | 1 |
| ten Cate, JW | 1 |
| Vos, J | 1 |
| Oosterhuis, H | 1 |
| Prenger, D | 1 |
| Jenkins, CS | 1 |
| Ulshen, MH | 1 |
| Grand, RJ | 1 |
| Crain, JD | 1 |
| Gelfand, EW | 1 |
| Thaler, MM | 1 |
| Brandt, KD | 1 |
| Lessell, S | 1 |
| Cohen, AS | 1 |
| Sillanpää, M | 1 |
| Mäkelä, AL | 1 |
| Koivikko, A | 1 |
| Rosenfeld, RG | 1 |
| Liebhaber, MI | 1 |
| Koike, T | 1 |
| Minakawa, T | 1 |
| Abe, H | 1 |
| Takeuchi, S | 1 |
| Sasaki, O | 1 |
| Nishimaki, K | 1 |
| Tanaka, R | 1 |
| Dickey, W | 1 |
| Morrow, JI | 1 |
| Smith, DB | 1 |
| Hitchcock, M | 1 |
| Philpott, PJ | 1 |
| Baker, M | 1 |
| Weiss, HJ | 1 |
| Hilty, MD | 1 |
| Romshe, CA | 1 |
| Delamater, PV | 1 |
| Boyd, EM | 1 |
| Meloff, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cilostazol Stroke Prevention Study-a Randomized, Double Blind, Double Dummy, Parallel Comparative, Multicenter Clinical Trial[NCT00202020] | Phase 3 | 720 participants | Interventional | 2004-05-31 | Completed | ||
| MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823] | 50 participants (Anticipated) | Observational | 2019-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for aspirin and Brain Disorders
| Article | Year |
|---|---|
Stroke in Pregnancy: A Multidisciplinary Approach.
Topics: Aspirin; Brain Diseases; Cardiomyopathies; Cesarean Section; Eclampsia; Embolism, Paradoxical; Femal | 2021 |
The treatment and prevention of deep vein thrombosis in the preoperative management of patients who have neurologic diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Brain Diseases; Chondroitin Sulfat | 2004 |
[Acute and chronic headaches].
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
An antagonist of prostaglandin synthesis in cardiovascular diseases.
Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Brain Diseases; Cardiovascular Diseases; Con | 1984 |
Metabolic mechanisms in Reye syndrome. End of a Mystery?
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Aspirin; Brain Diseases; Carbamoyl-Phosphate Synthase | 1976 |
Drug-induced neurological disorders.
Topics: Antihypertensive Agents; Aspirin; Brain Diseases; Dyskinesia, Drug-Induced; Humans; Levodopa; Nervou | 1990 |
Encephalopathy in toxicity tests on laboratory animals.
Topics: Animals; Aspirin; Atropine; Behavior, Animal; Brain Damage, Chronic; Brain Diseases; Caffeine; Casei | 1971 |
2 trials available for aspirin and Brain Disorders
| Article | Year |
|---|---|
Different impacts of blood pressure variability on the progression of cerebral microbleeds and white matter lesions.
Topics: Aspirin; Blood Pressure; Brain; Brain Diseases; Cerebral Hemorrhage; Cilostazol; Disease Progression | 2012 |
Psychopathology in systemic lupus erythematosus. I. Psychiatric observations.
Topics: Adolescent; Adult; Affective Symptoms; Aspirin; Azathioprine; Brain Diseases; Clinical Trials as Top | 1973 |
28 other studies available for aspirin and Brain Disorders
| Article | Year |
|---|---|
Is it coincidental or correlative between reversible splenial lesion syndrome and atrial septal defect?: A case report.
Topics: Administration, Oral; Antihypertensive Agents; Aspirin; Brain Diseases; Corpus Callosum; Diffusion M | 2020 |
Measurement of antiplatelet inhibition during neurointerventional procedures: the effect of antithrombotic duration and loading dose.
Topics: Aspirin; Blood Platelets; Brain Diseases; Clopidogrel; Cohort Studies; Dose-Response Relationship, D | 2010 |
A case of ecchordosis physaliphora presenting with an intratumoral hemorrhage.
Topics: Aspirin; Brain Diseases; Cranial Fossa, Posterior; Hamartoma; Headache; Humans; Magnetic Resonance I | 2009 |
Hughes syndrome (the antiphospholipid syndrome): a disease of our time.
Topics: Abortion, Spontaneous; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Arterial Occlusive D | 2011 |
Ocular tilt reaction due to a mesencephalic lesion in juvenile polyarteritis nodosa.
Topics: Aspirin; Brain Diseases; Child, Preschool; Cyclophosphamide; Diplopia; Drug Therapy, Combination; Fe | 2003 |
[PULMONARY ENCEPHALOPATHY].
Topics: Acidosis; Aspirin; Bicarbonates; Brain Diseases; Carbon Dioxide; Coma; Electroencephalography; Human | 1964 |
ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA.
Topics: Aspirin; Brain Diseases; Carbohydrate Metabolism; Coma; Fatty Liver; Heart Diseases; Humans; Kidney | 1965 |
A patient with cerebral Whipple's disease and a stroke-like syndrome.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Diseases; Ceftriaxone | 2005 |
Effects of aspirin and mefenamic acid on soman poisoning-induced neuropathology in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Brain Diseases; Cell Proliferation | 2006 |
Neurological picture. Susac's syndrome: effective combination of immunosuppression and antiplatelet treatment.
Topics: Adolescent; Aspirin; Brain Diseases; Corpus Callosum; Female; Glucocorticoids; Hearing Loss; Humans; | 2006 |
[Inhibition of prostaglandins in the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)].
Topics: Adult; Aged; Aspirin; Brain Diseases; Ethanol; Female; Humans; Inappropriate ADH Syndrome; Indometha | 1983 |
Noninvasive radioisotopic technique for detection of platelet deposition in mitral valve prostheses and quantitation of visceral microembolism in dogs.
Topics: Animals; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Dogs; Embolism; Heart Valve Prosthe | 1983 |
Bioavailability of rectal aspirin in neurosurgical patients.
Topics: Administration, Oral; Adult; Aged; Aspirin; Biological Availability; Brain Diseases; Female; Fever; | 1981 |
For your stroke-prone patients: a guide to drug treatment.
Topics: Aged; Antihypertensive Agents; Aspirin; Brain Diseases; Cerebral Angiography; Cerebrovascular Disord | 1980 |
Fraud and ethics charges hit stroke drug trial.
Topics: Aspirin; Brain Diseases; Cerebrovascular Disorders; Controlled Clinical Trials as Topic; Dipyridamol | 1996 |
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp | 1999 |
Determination of brain death via pulsatile echoencephalography.
Topics: Adult; Aspirin; Brain Death; Brain Diseases; Brain Injuries; Cerebrovascular Circulation; Echoenceph | 1978 |
Spontaneous platelet aggregation in cerebrovascular disease.
Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Aspirin; Blindness; Brain Diseases; Female; Humans; I | 1978 |
Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Biopsy; Brain Diseases; Chemical an | 1978 |
Cerebral disorders of vision in systemic lupus erythematosus.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Brain Diseases; Cerebrospinal Fluid; Electroencephalography | 1975 |
Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy.
Topics: Acute Disease; Adolescent; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Female; | 1975 |
Acute encephalopathy in siblings. Reye syndrome vs salicylate intoxication.
Topics: Aspirin; Brain; Brain Diseases; Child; Diagnosis, Differential; Female; Humans; Liver; Liver Disease | 1976 |
PTA of supra-aortic arteries with temporary balloon occlusion to avoid distal embolism.
Topics: Adult; Angioplasty, Balloon; Aortic Valve Stenosis; Aspirin; Brain Diseases; Carotid Artery Thrombos | 1992 |
Cerebral amyloid angiopathy presenting as transient ischemic attacks. Case report.
Topics: Aged; Amyloidosis; Anticoagulants; Aspirin; Brain; Brain Diseases; Humans; Ischemic Attack, Transien | 1985 |
Inhibition of platelet-induced thrombus formation.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Epinephrin | 1974 |
Reye's syndrome and hyperaminoacidemia.
Topics: Amino Acids; Aspirin; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Fatty Liver; | 1974 |
Reye's syndrome and salicylate intoxication.
Topics: Adipose Tissue; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Fatty Liver; Humans | 1970 |
Seizures and fever.
Topics: Acetaminophen; Acidosis, Respiratory; Age Factors; Alkalosis, Respiratory; Aspirin; Brain Diseases; | 1971 |