aspirin has been researched along with Bone Neoplasms in 30 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Herein, we describe the use of low-dose aspirin with high-dose MTX in a patient with osteosarcoma." | 8.98 | Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. ( Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E, 2018) |
| "MTT assay, colony formation assay, and apoptosis assay were employed to analyze the effects of aspirin on the osteosarcoma cell viability in vitro." | 7.81 | Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway. ( Duan, T; Hu, K; Kang, T; Liao, D; Lv, X; Wang, G; Wang, X; Zhang, RH; Zhong, L, 2015) |
| "3 nmol) of lipoxin A4 (LXA4), lipoxin B4 (LXB4) or aspirin-triggered-15-epi-lipoxin A4 (ATL) could alleviate the mechanical allodynia in CIBP on day 7 after surgery." | 7.78 | Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines. ( Hu, S; Huang, YL; Jiang, JW; Mao-Ying, QL; Mi, WL; Wang, J; Wang, XW; Wang, YQ; Wang, ZF; Wu, GC, 2012) |
| " We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer." | 7.65 | Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976) |
| " VOAspi-PbetaPL film inhibited cell proliferation in a dose-response manner and induced formation of approximately half of the thiobarbituric acid reactive substances (TBARS), an index of lipid peroxidation." | 5.31 | A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells. ( Alessandrini, JL; Cortizo, AM; Cortizo, MS; Etcheverr, SB, 2001) |
| "23 (60%) of 38 human breast carcinomas had significant in-vitro osteolytic activity." | 5.26 | Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin. ( Dowsett, M; Easty, DM; Easty, GC; Neville, AM; Powles, TJ, 1976) |
| "Thirteen patients with osteoid osteoma were enrolled in a prospective trial to test whether rofecoxib, a selective cyclooxygenase-2 inhibitor, is as effective for pain control as acetylsalicylic acid." | 5.09 | Cyclooxygenase-2 inhibitor for pain management in osteoid osteoma. ( Bottner, F; Grethen, C; Lindner, N; Roedl, R; Winkelmann, W; Wortler, K, 2001) |
| "Herein, we describe the use of low-dose aspirin with high-dose MTX in a patient with osteosarcoma." | 4.98 | Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. ( Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E, 2018) |
| "MTT assay, colony formation assay, and apoptosis assay were employed to analyze the effects of aspirin on the osteosarcoma cell viability in vitro." | 3.81 | Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway. ( Duan, T; Hu, K; Kang, T; Liao, D; Lv, X; Wang, G; Wang, X; Zhang, RH; Zhong, L, 2015) |
| "3 nmol) of lipoxin A4 (LXA4), lipoxin B4 (LXB4) or aspirin-triggered-15-epi-lipoxin A4 (ATL) could alleviate the mechanical allodynia in CIBP on day 7 after surgery." | 3.78 | Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines. ( Hu, S; Huang, YL; Jiang, JW; Mao-Ying, QL; Mi, WL; Wang, J; Wang, XW; Wang, YQ; Wang, ZF; Wu, GC, 2012) |
| " We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer." | 3.65 | Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976) |
| "Various strategies are emerging for dosing antiplatelet therapies in preparation for pipeline stent embolization in adults." | 2.55 | Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature. ( Cobb, MIH; Fernando Gonzalez, L; Hauck, EF; Smith, TP; Zomorodi, AR, 2017) |
| "Osteoid osteoma is a benign bone tumor." | 1.38 | [Osteoid osteoma in children: 5 cases treated with electrocoagulation]. ( Bodart, E; Charlier, H; de Wispelaere, JF; Gilliaux, O, 2012) |
| " VOAspi-PbetaPL film inhibited cell proliferation in a dose-response manner and induced formation of approximately half of the thiobarbituric acid reactive substances (TBARS), an index of lipid peroxidation." | 1.31 | A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells. ( Alessandrini, JL; Cortizo, AM; Cortizo, MS; Etcheverr, SB, 2001) |
| " Drug intervention should be on a regular schedule--avoid prn dosage of pain medications." | 1.27 | Dilemmas in managing prostate carcinoma (Part II): Metastatic disease. ( Ahmann, FR, 1985) |
| "23 (60%) of 38 human breast carcinomas had significant in-vitro osteolytic activity." | 1.26 | Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin. ( Dowsett, M; Easty, DM; Easty, GC; Neville, AM; Powles, TJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (56.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 9 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Renzi, S | 1 |
| Tsimerman, E | 1 |
| Taylor, T | 1 |
| Hopyan, S | 1 |
| Koo, A | 1 |
| Gupta, A | 1 |
| Mendez, GM | 1 |
| Patel, YM | 1 |
| Ricketti, DA | 1 |
| Gaughan, JP | 1 |
| Lackman, RD | 1 |
| Kim, TWB | 1 |
| Aisa, MC | 1 |
| Datti, A | 1 |
| Orlacchio, A | 1 |
| Di Renzo, GC | 1 |
| De Luna-Bertos, E | 1 |
| Ramos-Torrecillas, J | 1 |
| García-Martínez, O | 1 |
| Guildford, A | 1 |
| Santin, M | 1 |
| Ruiz, C | 1 |
| Liao, D | 1 |
| Zhong, L | 1 |
| Duan, T | 1 |
| Zhang, RH | 1 |
| Wang, X | 1 |
| Wang, G | 1 |
| Hu, K | 1 |
| Lv, X | 1 |
| Kang, T | 1 |
| Cobb, MIH | 1 |
| Zomorodi, AR | 1 |
| Hauck, EF | 1 |
| Smith, TP | 1 |
| Fernando Gonzalez, L | 1 |
| Patel, AR | 1 |
| Crist, MK | 1 |
| Nemitz, J | 1 |
| Mayerson, JL | 1 |
| Gilliaux, O | 1 |
| de Wispelaere, JF | 1 |
| Charlier, H | 1 |
| Bodart, E | 1 |
| Hu, S | 1 |
| Mao-Ying, QL | 1 |
| Wang, J | 1 |
| Wang, ZF | 1 |
| Mi, WL | 1 |
| Wang, XW | 1 |
| Jiang, JW | 1 |
| Huang, YL | 1 |
| Wu, GC | 1 |
| Wang, YQ | 1 |
| Meijer-Jorna, LB | 1 |
| Slingerland, AC | 1 |
| Blaauwgeers, JL | 1 |
| Uluçkan, O | 1 |
| Eagleton, MC | 1 |
| Floyd, DH | 1 |
| Morgan, EA | 1 |
| Hirbe, AC | 1 |
| Kramer, M | 1 |
| Dowland, N | 1 |
| Prior, JL | 1 |
| Piwnica-Worms, D | 1 |
| Jeong, SS | 1 |
| Chen, R | 1 |
| Weilbaecher, K | 1 |
| Powles, TJ | 6 |
| Dady, PJ | 1 |
| Williams, J | 1 |
| Easty, GC | 5 |
| Coombes, RC | 3 |
| Bottner, F | 1 |
| Roedl, R | 1 |
| Wortler, K | 1 |
| Grethen, C | 1 |
| Winkelmann, W | 1 |
| Lindner, N | 1 |
| Cortizo, MS | 1 |
| Alessandrini, JL | 1 |
| Etcheverr, SB | 1 |
| Cortizo, AM | 1 |
| Dowsett, M | 2 |
| Easty, DM | 4 |
| Neville, AM | 6 |
| Bennett, A | 1 |
| Charlier, EM | 1 |
| McDonald, AM | 1 |
| Simpson, JS | 1 |
| Stamford, IF | 1 |
| Zebro, T | 1 |
| Gazet, JC | 2 |
| Ford, HT | 1 |
| Nash, AG | 1 |
| Baker, JW | 1 |
| Powles, JT | 1 |
| Bondy, PK | 1 |
| Hanks, GW | 1 |
| Ahmann, FR | 1 |
| LiVolsi, VA | 1 |
| Hart, FD | 1 |
| Clark, SA | 1 |
| Sandberg, A | 1 |
| Litchman, HM | 1 |
| Byers, PD | 1 |
| Vailati, G | 1 |
| Montini, M | 1 |
| Bonicelli, A | 1 |
| Pagani, G | 1 |
| Schvingt, E | 1 |
| Weill, D | 1 |
| Petit, R | 1 |
2 reviews available for aspirin and Bone Neoplasms
| Article | Year |
|---|---|
Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature.
Topics: Aspirin; Bone Neoplasms; Child; Glomerular Filtration Rate; Humans; Male; Methotrexate; Osteosarcoma | 2018 |
Optimal pediatric dosing of anti-platelet agents for pipeline stent embolization -a case report and review of the literature.
Topics: Adolescent; Aspirin; Bone Neoplasms; Cerebral Hemorrhage; Clopidogrel; Embolization, Therapeutic; Fe | 2017 |
2 trials available for aspirin and Bone Neoplasms
| Article | Year |
|---|---|
Use of inhibitors of prostaglandin synthesis in patients with breast cancer.
Topics: Acetaminophen; Aspirin; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Double-Blind Met | 1980 |
Cyclooxygenase-2 inhibitor for pain management in osteoid osteoma.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Cyclooxygenase | 2001 |
26 other studies available for aspirin and Bone Neoplasms
| Article | Year |
|---|---|
Aspirin for Prophylaxis Against Venous Thromboembolism After Orthopaedic Oncologic Surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Bone Neoplasms; Female; Humans; | 2017 |
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Cathepsin B; Cell Differentiation; | 2018 |
Therapeutic doses of nonsteroidal anti-inflammatory drugs inhibit osteosarcoma MG-63 osteoblast-like cells maturation, viability, and biomineralization potential.
Topics: Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation; Aspirin; B | 2013 |
Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF-κB Pathway.
Topics: Animals; Apoptosis; Aspirin; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Ce | 2015 |
Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
Topics: Adult; Aged; Aspirin; Bone Neoplasms; Female; Heparin; Heparin, Low-Molecular-Weight; Humans; Interm | 2010 |
[Osteoid osteoma in children: 5 cases treated with electrocoagulation].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Electrocoagulation; Fe | 2012 |
Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Carcinoma 256, Walker; Di | 2012 |
[Diagnostic image (93). A boy with a painful leg swelling. Osteoid osteoma].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Humans; Male; Osteoma, | 2002 |
APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apyrase; Aspirin; Bone Neoplasms; Diagnosti | 2008 |
A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells.
Topics: Animals; Aspirin; Bone Neoplasms; Cell Division; Drug Combinations; Drug Delivery Systems; Kinetics; | 2001 |
Breast-cancer osteolysis, bone metastases, and anti-osteolytic effect of aspirin.
Topics: Animals; Aspirin; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Cultur | 1976 |
Prostaglandins and breast cancer.
Topics: Adolescent; Adult; Aged; Aspirin; Bone Neoplasms; Breast Neoplasms; Female; Humans; In Vitro Techniq | 1977 |
Anti-inflammatory drugs and tumour growth.
Topics: Animals; Aspirin; Bone Neoplasms; Carcinogens; Drug Evaluation; Humans; Indomethacin; Neoplasm Metas | 1979 |
Agents affecting osteolysis in patients with breast cancer.
Topics: Anti-Inflammatory Agents; Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Fe | 1979 |
In vitro osteolysis by human breast tumours.
Topics: Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Female; Humans; In Vitro Techni | 1977 |
Failure of indomethacin to reduce hypercalcemia in patients with breast cancer.
Topics: Aspirin; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Humans; Hydroxyproline; Hype | 1976 |
Drug treatments for relief of pain due to bone metastases.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Delayed | 1985 |
Dilemmas in managing prostate carcinoma (Part II): Metastatic disease.
Topics: Aged; Aminoglutethimide; Aspirin; Bone Neoplasms; Castration; Diethylstilbestrol; Disseminated Intra | 1985 |
Anti-metastatic effect of aspirin.
Topics: Animals; Aspirin; Bone Neoplasms; Bone Resorption; Carcinoma 256, Walker; Indomethacin; Lysosomes; N | 1973 |
Anti-metastatic effect of aspirin.
Topics: Animals; Aspirin; Bone Neoplasms; Bone Resorption; In Vitro Techniques; Indomethacin; Mice; Neoplasm | 1973 |
Analgesics and non-steroid anti-inflammatory agents in rheumatic disease.
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bone Neoplasms; Gout; Humans; | 1972 |
The inhibition by aspirin and indomethacin of osteolytic tumor deposits and hypercalcaemia in rats with Walker tumour, and its possible application to human breast cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Calciu | 1973 |
Clinical conference: night pains in a four-year-old child.
Topics: Aspirin; Bone Neoplasms; Child, Preschool; Humans; Male; Osteoma, Osteoid; Pain | 1967 |
Solitary benign osteoblastic lesions of bone. Osteoid osteoma and benign osteoblastoma.
Topics: Adult; Age Factors; Aspirin; Axons; Bone and Bones; Bone Neoplasms; Diagnosis, Differential; Female; | 1968 |
[Clinical-experimental study of lysine acetylsalicylate].
Topics: Adolescent; Adult; Aged; Aspirin; Blood Coagulation; Bone Neoplasms; Female; Fever; Fractures, Bone; | 1971 |
[Centro-medullar boring with closed focus for osteoid osteoma of the tibia].
Topics: Aspirin; Bone Neoplasms; Child; Humans; Male; Methods; Osteoma, Osteoid; Radiography; Tibia | 1969 |