aspirin has been researched along with Bone Diseases in 16 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Bone Diseases: Diseases of BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain." | 9.05 | Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983) |
| "The effectiveness and safety of suprofen 200 mg, aspirin 650 mg, and placebo in the treatment of moderate to severe pain were compared in a 72-hour multiple-dose, double-blind, parallel, randomized study in 75 adults suffering from musculoskeletal pain." | 5.05 | Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain. ( Silberman, HM, 1983) |
| "A 13-year-old boy affected by bursitis of the R knee and nonossifying fibroma of the distal metaphysis of the R femur, was treated in the weeks prior to surgical intervention with water-soluble aspirin tablets to relieve local pain." | 3.66 | Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism. ( Comelli, A; Cozzutto, C, 1982) |
| "Aspirin treatment also had favorable therapeutic effects on bone regeneration in the bone defect model, and the number of osteoclasts was decreased." | 1.51 | Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation. ( Bai, Y; Du, J; Guo, L; Jia, L; Jiang, Y; Liu, Y; Luo, Z; Wu, L, 2019) |
| "On the other hand, certain tumors require local blockade as in cases with pancreatic or perianal tumors." | 1.27 | [Therapy of pain caused by gastrointestinal tumors]. ( Zenz, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, L | 1 |
| Luo, Z | 1 |
| Liu, Y | 2 |
| Jia, L | 1 |
| Jiang, Y | 1 |
| Du, J | 1 |
| Guo, L | 1 |
| Bai, Y | 1 |
| Cozzutto, C | 1 |
| Comelli, A | 1 |
| Silberman, HM | 1 |
| Andersen, LA | 1 |
| Gøtzsche, PC | 1 |
| Diaz, C | 1 |
| Gassó, FC | 1 |
| Panadés, JN | 1 |
| Nielsen, IL | 1 |
| Rasmussen, S | 1 |
| Hilden, T | 1 |
| Essigman, WK | 2 |
| Chamberlain, MA | 2 |
| Wright, V | 2 |
| Ortolani, C | 1 |
| Bellasio, G | 1 |
| Bertini, M | 1 |
| Pastorello, E | 1 |
| Viara, M | 1 |
| Amato, AM | 1 |
| Menicanti, V | 1 |
| Longatti, S | 1 |
| Heere, LP | 1 |
| Zenz, M | 1 |
| O'Brien, WM | 1 |
| Bagby, GF | 1 |
| Doutre, LP | 1 |
| Périssat, J | 1 |
| Isemein, L | 1 |
| Brusquet, Y | 1 |
| Mignard, P | 1 |
| Sans-Solá, L | 1 |
| Barceló, P | 1 |
7 trials available for aspirin and Bone Diseases
| Article | Year |
|---|---|
Multiple-dose comparison of suprofen, aspirin, and placebo in the treatment of musculoskeletal pain.
Topics: Adolescent; Adult; Aged; Aspirin; Bone Diseases; Clinical Trials as Topic; Dose-Response Relationshi | 1983 |
Naproxen and aspirin in acute musculoskeletal disorders: a double-blind, parallel study in patients with sports injuries.
Topics: Adolescent; Adult; Aged; Aspirin; Athletic Injuries; Bone Diseases; Clinical Trials as Topic; Double | 1984 |
Double-blind study of the analgesic activity of fosfosal in patients with musculoskeletal and articular pain: comparison with lysine acetylsalicylate and placebo.
Topics: Aged; Analgesics; Aspirin; Bone Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1981 |
Diflunisal in osteoarthrosis of the hip and knee.
Topics: Adult; Aged; Analgesics; Aspirin; Biphenyl Compounds; Bone Diseases; Clinical Trials as Topic; Femal | 1978 |
Diflunisal in osteoarthrosis of the hip and knee.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Diseases; Clinical Trials as Top | 1979 |
[Comparative clinical study of tiaprofenic acid and lysine acetylsalicylate in aged osteoarthrosis patients].
Topics: Administration, Oral; Aged; Analgesics; Aspirin; Bone Diseases; Female; Humans; Joint Diseases; Lysi | 1987 |
Piroxicam in acute musculoskeletal disorders and sports injuries.
Topics: Activities of Daily Living; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Athl | 1988 |
9 other studies available for aspirin and Bone Diseases
| Article | Year |
|---|---|
Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation.
Topics: Animals; Apoptosis; Aspirin; Bone Diseases; Bone Regeneration; CD11c Antigen; Cell Differentiation; | 2019 |
Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism.
Topics: Adolescent; Aspirin; Bone Diseases; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Femoral Neo | 1982 |
Acetylsalicylic acid and renal function.
Topics: Aged; Aspirin; Bone Diseases; Creatinine; Female; Giant Cell Arteritis; Glomerular Filtration Rate; | 1980 |
[Study of the therapeutic effectiveness of diphenpyramide in the treatment of arthropathies, as compared with acetylsalicylic acid].
Topics: Acetamides; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Biphenyl Compounds; Bone Diseases; Drug | 1979 |
[Therapy of pain caused by gastrointestinal tumors].
Topics: Acetaminophen; Aspirin; Bone Diseases; Dipyrone; Humans; Injections, Epidural; Narcotics; Neoplasms; | 1987 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Biomechanical Phenomena; Bone Diseases; Drug Hypersensiti | 1985 |
[Propofan as an antalgic in general surgery. Apropos of 50 cases].
Topics: Acetaminophen; Analgesics; Aspirin; Bone Diseases; Caffeine; Chlorpheniramine; Dextropropoxyphene; D | 1972 |
[Clinical trial of a new long-acting salicylate].
Topics: Adolescent; Adult; Aged; Aspirin; Bone Diseases; Delayed-Action Preparations; Female; Humans; Joint | 1967 |
[Aspirin in the treatment of rheumatic diseases. Results obtained with the use of an acetylsalicylic acid and glycine compound].
Topics: Arthritis, Rheumatoid; Aspirin; Bone Diseases; Gout; Humans; Sciatica; Spondylitis, Ankylosing | 1965 |