aspirin has been researched along with Body Weight, Fetal in 4 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fetal body weight was significantly lower in COX-exposed group of fetuses when compared with untreated control." | 1.33 | Celosomy is associated with prenatal exposure to cyclooxygenase inhibitors. ( Burdan, F; Dudka, J; Klepacz, R; Korobowicz, A; Szumilo, J, 2006) |
| " The objectives of the current study were to comprehensively define the developmental toxicology profile of ASA in rabbits by using a dosing paradigm encompassing the period of organogenesis and to test the hypothesis that maternal gastrointestinal toxicity after repeated dose administrations hampers the detection of low-incidence malformations with ASA in rabbits by limiting ASA administration to sensitive windows for cardiovascular development and midline closure." | 1.32 | Comparison of the developmental toxicity of aspirin in rabbits when administered throughout organogenesis or during sensitive windows of development. ( Cappon, GD; Cook, JC; Gupta, U; Hurtt, ME; Tassinari, MS, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, MK | 1 |
| Amin, ME | 1 |
| Amin, AF | 1 |
| Abd El Aal, DEM | 1 |
| Vieira-Filho, LD | 1 |
| Lucena-Júnior, JM | 1 |
| Barreto, IS | 1 |
| Angelim, JL | 1 |
| Paixão, AD | 1 |
| Cappon, GD | 1 |
| Gupta, U | 1 |
| Cook, JC | 1 |
| Tassinari, MS | 1 |
| Hurtt, ME | 1 |
| Burdan, F | 1 |
| Szumilo, J | 1 |
| Dudka, J | 1 |
| Korobowicz, A | 1 |
| Klepacz, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02696577] | Phase 2 | 68 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for aspirin and Body Weight, Fetal
| Article | Year |
|---|---|
Evaluation of the effectiveness of low-dose aspirin and omega 3 in treatment of asymmetrically intrauterine growth restriction: A randomized clinical trial.
Topics: Adult; Aspirin; Fatty Acids, Omega-3; Female; Fetal Growth Retardation; Fetal Weight; Fibrinolytic A | 2017 |
3 other studies available for aspirin and Body Weight, Fetal
| Article | Year |
|---|---|
Repercussion of acetylsalicylic acid during fetal development on later renal hemodynamics of rats.
Topics: Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Female; Fetal Development; Fetal Weight | 2008 |
Comparison of the developmental toxicity of aspirin in rabbits when administered throughout organogenesis or during sensitive windows of development.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; | 2003 |
Celosomy is associated with prenatal exposure to cyclooxygenase inhibitors.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cyclooxygenase Inhibitors; Female; Fetal Weight; Fetu | 2006 |