Page last updated: 2024-10-23

aspirin and Blunt Injuries

aspirin has been researched along with Blunt Injuries in 30 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"A randomized, controlled study was conducted in 51 patients to investigate the effect of aspirin administration on traumatic hyphema."9.06Aspirin and secondary bleeding after traumatic hyphema. ( Biedner, B; Lifshitz, T; Marcus, M; Yassur, Y, 1988)
"We report a rare case in which life-threatening subcutaneous hemorrhage following minor blunt trauma developed in an elderly patient taking ticlopidine and aspirin."7.73Life-threatening subcutaneous hemorrhage following minor blunt trauma in an elderly patient taking ticlopidine and aspirin: a case report. ( Hagiwara, A; Matsuda, T; Shimazaki, S, 2005)
"A randomized, controlled study was conducted in 51 patients to investigate the effect of aspirin administration on traumatic hyphema."5.06Aspirin and secondary bleeding after traumatic hyphema. ( Biedner, B; Lifshitz, T; Marcus, M; Yassur, Y, 1988)
" Although evidence was limited, it appears that people with traumatic hyphema who receive aminocaproic acid or tranexamic acid are less likely to experience secondary hemorrhaging."5.01Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2019)
"We report a rare case in which life-threatening subcutaneous hemorrhage following minor blunt trauma developed in an elderly patient taking ticlopidine and aspirin."3.73Life-threatening subcutaneous hemorrhage following minor blunt trauma in an elderly patient taking ticlopidine and aspirin: a case report. ( Hagiwara, A; Matsuda, T; Shimazaki, S, 2005)
"Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye."2.49Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2013)
"Traumatic hyphema is the entry of blood into the anterior chamber (the space between the cornea and iris) subsequent to a blow or a projectile striking the eye."2.47Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, K; Savage, HI; Scherer, RW, 2011)
"Although acute stroke is also relatively common in this population, two thirds of strokes are already evident on admission."1.72Imaging analysis of ischemic strokes due to blunt cerebrovascular injury. ( Abraham, MN; Abraham, PJ; Black, JA; Griffin, RL; Harrigan, MR; Holcomb, JB; Jansen, JO; Kerby, JD; Liptrap, EJ; Thaci, B, 2022)
"A 37-year-old woman with idiopathic thrombocytopenic purpura (ITP) suffered from multiple trauma scheduled for open reduction and internal fixation for right tibial and left radius fracture five days after SAE."1.48Bilateral visual loss and cerebral infarction after spleen embolization in a trauma patient with idiopathic thrombocytopenic purpura: A case report. ( Chen, JY; Hung, KC; Lan, KM; Li, YY; Lin, WC; Sun, CK; Wang, WT, 2018)
"The number of anticoagulated trauma patients is increasing."1.46Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial. ( Barmparas, G; Bosarge, P; Brown, CV; Bukur, M; Carrick, MM; Catalano, RD; Coimbra, R; Holly-Nicolas, J; Inaba, K; Kaminski, S; Klein, AL; Kobayashi, L; Kopelman, T; Ley, EJ; Martinez, EM; Moore, FO; Murry, J; Nirula, R; Paul, D; Quick, J; Rivera, O; Schreiber, M, 2017)
"Blunt carotid artery injuries (BCI) are being recognized and treated with increasing frequency because of improved screening protocols."1.35Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm. ( Berne, JD; McGovern, TM; Norwood, SH; Reuland, KR; Rowe, SA; Villarreal, DH, 2008)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.67)18.7374
1990's4 (13.33)18.2507
2000's5 (16.67)29.6817
2010's10 (33.33)24.3611
2020's6 (20.00)2.80

Authors

AuthorsStudies
Abraham, PJ1
Black, JA1
Griffin, RL1
Abraham, MN1
Liptrap, EJ1
Thaci, B1
Holcomb, JB2
Kerby, JD1
Harrigan, MR1
Jansen, JO1
Catapano, JS1
Israr, S1
Whiting, AC1
Hussain, OM1
Snyder, LA1
Albuquerque, FC1
Ducruet, AF1
Nakaji, P1
Lawton, MT1
Weinberg, JA1
Zabramski, JM1
Liagkos, G1
Spyropoulos, C1
Chouliaras, C1
Tsourouflis, G1
Kouraklis, G1
Vagianos, CE1
Sticco, A1
Gandhi, SS1
Knoedler, B1
Marston, G1
Ewing, A1
Langan, EM1
Carsten, CG1
Paketci, S1
Hanna, K1
Khurrum, M1
Joseph, B1
Huang, JF1
Cheng, CT1
Fu, CY1
Huang, YA1
Hsu, CP1
OuYang, CH1
Liao, CH1
Hsieh, CH1
Chang, SH1
Kobayashi, L1
Barmparas, G1
Bosarge, P1
Brown, CV1
Bukur, M1
Carrick, MM1
Catalano, RD1
Holly-Nicolas, J1
Inaba, K1
Kaminski, S1
Klein, AL1
Kopelman, T1
Ley, EJ1
Martinez, EM1
Moore, FO1
Murry, J1
Nirula, R1
Paul, D1
Quick, J1
Rivera, O1
Schreiber, M1
Coimbra, R1
Chang, R1
Scerbo, MH1
Schmitt, KM1
Adams, SD1
Choi, TJ1
Wade, CE1
Wang, WT1
Li, YY1
Lin, WC1
Chen, JY1
Lan, KM1
Sun, CK1
Hung, KC1
Rose, EAC1
Sherwin, T1
Gharaibeh, A3
Savage, HI3
Scherer, RW3
Goldberg, MF3
Lindsley, K3
Sasaki, T1
Temmoku, J1
Inukai, T1
Sugiyama, T1
Inokuchi, R1
Shinohara, K1
Fortuna, GR1
Mueller, EW1
James, LE1
Shutter, LA1
Butler, KL1
Gopal, SV1
Smith, I1
Malka, V1
Capone, C1
Burjonrappa, S1
Hagiwara, A1
Matsuda, T1
Shimazaki, S1
Berne, JD1
Reuland, KR1
Villarreal, DH1
McGovern, TM1
Rowe, SA1
Norwood, SH1
Ganley, JP1
Geiger, JM1
Clement, JR1
Rigby, PG1
Levy, GJ1
Alberhasky, M1
Nichols, GR1
Lavach, JD1
Severin, GA1
Roberts, SM1
Colella, JJ1
Diamond, DL1
Murley, RS1
Hurt, RL1
Ghigliotti, G1
Waissbluth, AR1
Speidel, C1
Abendschein, DR1
Eisenberg, PR1
Eachempati, SR1
Sebastian, MW1
Reed, RL1
Roisinblit, JM1
Allende, NG1
Neira, JA1
Torino, AF1
Karmazyn, C1
Pardo, P1
Scattini, G1
Marcus, M1
Biedner, B1
Lifshitz, T1
Yassur, Y1
Witteman, GJ1
Brubaker, SJ1
Johnson, M1
Marks, RG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot, Non-masked, Randomized Clinical Trial for Evaluation of Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).[NCT05868525]Phase 498 participants (Anticipated)Interventional2024-04-30Recruiting
The AHEAD Study: Monitoring Anticoagulated Patients Who Suffer Head Injury[NCT02461498]3,556 participants (Actual)Observational2011-07-31Completed
Evaluation of Portal Venous System Thrombosis After Blunt Splenic Trauma Utilizing Doppler Ultrasound[NCT01906983]80 participants (Anticipated)Observational [Patient Registry]2013-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aspirin and Blunt Injuries

ArticleYear
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2019, 01-14, Volume: 1

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Ch

2019
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2013, Dec-03, Issue:12

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Es

2013
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Bandages; Bed Rest; Es

2011
Prolonged activation of prothrombin on the vascular wall after arterial injury.
    Arteriosclerosis, thrombosis, and vascular biology, 1998, Volume: 18, Issue:2

    Topics: Animals; Anticoagulants; Arteries; Aspirin; Blood Coagulation Factors; Blood Platelets; Factor X; Fa

1998
Posttraumatic bilateral carotid artery and right vertebral artery dissections in a patient with fibromuscular dysplasia: case report and review of the literature.
    The Journal of trauma, 1998, Volume: 44, Issue:2

    Topics: Accidents, Traffic; Adult; Aortic Dissection; Aspirin; Carotid Artery Diseases; Female; Fibromuscula

1998

Trials

1 trial available for aspirin and Blunt Injuries

ArticleYear
Aspirin and secondary bleeding after traumatic hyphema.
    Annals of ophthalmology, 1988, Volume: 20, Issue:4

    Topics: Adult; Aspirin; Clinical Trials as Topic; Eye Injuries; Hemorrhage; Humans; Hyphema; Recurrence; Wou

1988

Other Studies

24 other studies available for aspirin and Blunt Injuries

ArticleYear
Imaging analysis of ischemic strokes due to blunt cerebrovascular injury.
    The journal of trauma and acute care surgery, 2022, 06-01, Volume: 92, Issue:6

    Topics: Aspirin; Cerebrovascular Trauma; Humans; Ischemic Stroke; Retrospective Studies; Stroke; Wounds, Non

2022
Management of Extracranial Blunt Cerebrovascular Injuries: Experience with an Aspirin-Based Approach.
    World neurosurgery, 2020, Volume: 133

    Topics: Adolescent; Adult; Aged; Anticoagulants; Aortic Dissection; Aspirin; Carotid Artery Injuries; Caroti

2020
Management of blunt hepatic and splenic injuries (grade ≤ III) in patients receiving antithrombotic therapy.
    Annali italiani di chirurgia, 2019, Volume: 90

    Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Aspirin; Blood Coagulation Factors; Blood Transfusion

2019
Current Outcomes of Blunt Vertebral Artery Injuries.
    Annals of vascular surgery, 2021, Volume: 70

    Topics: Adult; Aged; Anticoagulants; Aspirin; Embolization, Therapeutic; Female; Humans; Incidence; Injury S

2021
In response to: Female sex as a risk factor for blunt cerebrovascular injuries and aspirin resistance.
    The journal of trauma and acute care surgery, 2021, 02-01, Volume: 90, Issue:2

    Topics: Anticoagulants; Aspirin; Cerebrovascular Trauma; Female; Humans; Platelet Aggregation Inhibitors; Ri

2021
Authors' reply: Aspirin resistance and blunt cerebrovascular injuries among female patients.
    The journal of trauma and acute care surgery, 2021, 02-01, Volume: 90, Issue:2

    Topics: Anticoagulants; Aspirin; Cerebrovascular Trauma; Female; Humans; Platelet Aggregation Inhibitors; Wo

2021
Aspirin does not increase the need for haemostatic interventions in blunt liver and spleen injuries.
    Injury, 2021, Volume: 52, Issue:9

    Topics: Aspirin; Hemostatics; Humans; Injury Severity Score; Liver; Retrospective Studies; Spleen; Splenecto

2021
Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial.
    The journal of trauma and acute care surgery, 2017, Volume: 82, Issue:5

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Clopidogrel; Dabigatran; Female; Humans; Injury

2017
Early chemoprophylaxis is associated with decreased venous thromboembolism risk without concomitant increase in intraspinal hematoma expansion after traumatic spinal cord injury.
    The journal of trauma and acute care surgery, 2017, Volume: 83, Issue:6

    Topics: Adult; Anticoagulants; Aspirin; Chemoprevention; Female; Follow-Up Studies; Hematoma, Epidural, Spin

2017
Bilateral visual loss and cerebral infarction after spleen embolization in a trauma patient with idiopathic thrombocytopenic purpura: A case report.
    Medicine, 2018, Volume: 97, Issue:16

    Topics: Adult; Aspirin; Blindness, Cortical; Brain Ischemia; Embolization, Therapeutic; Female; Humans; Magn

2018
Carotid Dissection and Cerebral Infarction From Posterior Oropharyngeal Trauma: The Diagnostic and Therapeutic Challenges.
    Pediatric emergency care, 2019, Volume: 35, Issue:1

    Topics: Aspirin; Carotid Arteries; Carotid Artery, Internal, Dissection; Cerebral Infarction; Child, Prescho

2019
Acute myocardial infarction after trauma: potency of percutaneous coronary intervention with transcatheter arterial embolization.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:6

    Topics: Accidents, Traffic; Aged; Aspirin; Coronary Angiography; Embolization, Therapeutic; Humans; Male; My

2016
The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury.
    Surgery, 2008, Volume: 144, Issue:4

    Topics: Age Factors; Aged; Anticoagulants; Aspirin; Brain Hemorrhage, Traumatic; Cardiovascular Diseases; Ca

2008
Acute portal venous thrombosis after blunt abdominal trauma.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:3

    Topics: Abdominal Injuries; Accidents, Traffic; Adult; Anticoagulants; Aspirin; Drug Therapy, Combination; H

2009
Congenital spine deformities: a new screening indication for blunt cerebrovascular injuries after cervical trauma?
    Journal of pediatric surgery, 2010, Volume: 45, Issue:12

    Topics: Anticoagulants; Aspirin; Carotid Artery, Internal, Dissection; Cerebral Angiography; Cervical Atlas;

2010
Life-threatening subcutaneous hemorrhage following minor blunt trauma in an elderly patient taking ticlopidine and aspirin: a case report.
    Emergency radiology, 2005, Volume: 12, Issue:1-2

    Topics: Abdominal Injuries; Accidental Falls; Aged, 80 and over; Aspirin; Embolization, Therapeutic; Female;

2005
Internal carotid artery stenting for blunt carotid artery injuries with an associated pseudoaneurysm.
    The Journal of trauma, 2008, Volume: 64, Issue:2

    Topics: Accidents, Traffic; Adolescent; Adult; Aneurysm, False; Aspirin; Carotid Artery Injuries; Carotid Ar

2008
Aspirin and recurrent hyphema after blunt ocular trauma.
    American journal of ophthalmology, 1983, Volume: 96, Issue:6

    Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Eye Injuries; Female; Humans; Hyphema; Male; Mi

1983
Fatal hemorrhage from minor trauma following massive salicylate ingestion.
    The American journal of forensic medicine and pathology, 1984, Volume: 5, Issue:2

    Topics: Alcoholism; Aspirin; Death, Sudden; Hemorrhage; Humans; Lung Diseases; Male; Mediastinal Diseases; M

1984
Lacerations of the equine eye: a review of 48 cases.
    Journal of the American Veterinary Medical Association, 1984, May-15, Volume: 184, Issue:10

    Topics: Animals; Aspirin; Cornea; Corneal Injuries; Horse Diseases; Horses; Postoperative Care; Prognosis; S

1984
Blunt carotid injury: reassessing the role of anticoagulation.
    The American surgeon, 1996, Volume: 62, Issue:3

    Topics: Adult; Anticoagulants; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Cerebral Angiogra

1996
Extrapleural haematoma secondary to blunt chest trauma.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1996, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Fatal Outcome; Hematoma; Humans; Male; Pleural Diseases; Thoracic

1996
Local thrombus as an isolated sign of traumatic aortic injury.
    Echocardiography (Mount Kisco, N.Y.), 2002, Volume: 19, Issue:1

    Topics: Accidents, Traffic; Adult; Aorta, Thoracic; Aspirin; Echocardiography, Transesophageal; Female; Foll

2002
The incidence of rebleeding in traumatic hyphema.
    Annals of ophthalmology, 1985, Volume: 17, Issue:9

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Analysis of Variance; Aspirin; Child;

1985