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aspirin and Blood Pressure, High

aspirin has been researched along with Blood Pressure, High in 820 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that individuals with twin pregnancies, a history of preeclampsia, or hypertension may not benefit from aspirin to the same extent as those with other complications such as obesity or diabetes."9.69Persisting risk factors for preeclampsia among high-risk pregnancies already using prophylactic aspirin: a multi-country retrospective investigation. ( Corsi, DJ; Dagvadorj, A; Dingwall-Harvey, ALJ; El-Chaár, D; Gaudet, LM; Guo, Y; McLean, C; Muldoon, KA; Rennicks White, R; Rybak, N; Walker, MC; Wen, SW, 2023)
"Ticagrelor-aspirin was associated with reduced risk of new stroke in patients without hypertension (32 [4."9.51Effect of Hypertension on Efficacy and Safety of Ticagrelor-Aspirin Versus Clopidogrel-Aspirin in Minor Stroke or Transient Ischemic Attack. ( Bath, PM; Chen, G; Huang, P; Jiang, Y; Jing, J; Johnston, SC; Li, H; Li, Z; Lin, J; Liu, L; Meng, X; Tian, X; Wang, A; Wang, F; Wang, Y; Xie, X; Zhao, X; Zuo, Y, 2022)
"This study was to study the efficacy of rosuvastatin, amlodipine, and aspirin in the treatment of hypertension with coronary heart disease and its effect on platelet aggregation."9.51The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation. ( Fu, J; Li, B; Wang, T; Zhao, N, 2022)
"This systematic review and meta-analysis investigated whether the use of low-dose aspirin during pregnancy by women with chronic hypertension reduces the odds of superimposed preeclampsia and poor perinatal outcomes."9.41Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis. ( Giorgione, V; Richards, EMF; Stevens, O; Thilaganathan, B, 2023)
"The aim of the study is to evaluate the effects of supplementation with Arginine (L-Arg) 3g, (together with Magnesium (Mg) 350 mg and Salicilate (Sal) 100 mg) on maternal blood pressure (BP), uterine artery doppler PI and neonatal outcomes in women with high-risk pregnancy for chronic hypertension (CH) and other previous placenta vascular disorders (PVD) already treated with low dose of aspirin (LDA), as recommended by guidelines."9.41Effect of L-arginine supplementation in pregnant women with chronic hypertension and previous placenta vascular disorders receiving Aspirin prophylaxis: a randomized control trial. ( Basile, L; Facchinetti, F; Menichini, D; Monari, F; Neri, I; Pignatti, L, 2021)
"This study aimed to evaluate the maternal and fetal results in women undergoing antihypertensive therapy (low aspirin or labetalol) with mild to severe chronic hypertension relative to women without medicines."9.34Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo. ( Wang, F; Xiang, X; Zhao, N; Zhou, Z, 2020)
"A total of 14 464 patients (age, 60-85 years) with hypertension, dyslipidemia, and diabetes mellitus participated and were randomized into 2 treatment groups: 100 mg of aspirin or no aspirin."9.22Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project. ( Ando, K; Ikeda, Y; Ishizuka, N; Matsumoto, M; Minematsu, K; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2016)
"The aim of this study is to analyze the effect of 100 mg/d regular oral intake of aspirin during pregnancy on high-risk pregnancy-induced hypertension syndrome patients."9.22Effect of regular oral intake of aspirin during pregnancy on pregnancy outcome of high-risk pregnancy-induced hypertension syndrome patients. ( Li, L; Liu, FM; Wang, M; Yang, HL; Zhao, M, 2016)
" In the present retrospective analysis of the randomized, double-blind, parallel-group, SMILE-4 study we compared the efficacy of zofenopril 60 mg and acetylsalicylic acid (ASA) 100 mg versus ramipril 10 mg and ASA in patients with AMI complicated by left ventricular dysfunction, classified according to a history of hypertension."9.17Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study. ( Ambrosio, G; Ambrosioni, E; Bacchelli, S; Borghi, C; Cicero, AF; Esposti, DD; Omboni, S; Vinereanu, D; Zava, D, 2013)
"In a laboratory substudy of the PRAGUE-8 trial, the influences of nonmodifiable (age and sex) and modifiable (body mass index and tobacco smoke) factors, comorbidity (hypertension, hyperlipidemia, diabetes mellitus, and renal insufficiency) and cotherapy (statin, aspirin, and heparin), on the course of clopidogrel efficacy were investigated in 105 patients pretreated with clopidogrel >or=6 hours before coronary angiography +/- percutaneous coronary intervention."9.14Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox". ( Bilkova, D; Kala, P; Marinov, I; Motovska, Z; Petr, R; Simek, S; Widimsky, P, 2009)
"The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study is an international double-blind, randomized controlled trial designed to investigate the superiority of the specific TP receptor antagonist terutroban (30 mg/day) over aspirin (100 mg/day), in reducing cerebrovascular and cardiovascular events in patients with a recent history of ischemic stroke or transient ischemic attack."9.14The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study: baseline characteristics of the population. ( Amarenco, P; Bousser, MG; Chamorro, A; Fisher, M; Ford, I; Fox, K; Hennerici, M; Mattle, HP; Rothwell, PM, 2009)
"Aspirin has been found to prevent angiotensin II-induced hypertension and to induce nitric oxide (NO) release from vascular endothelium."9.14Ambulatory blood pressure control with bedtime aspirin administration in subjects with prehypertension. ( Ayala, DE; Fernández, JR; Hermida, RC; Mojón, A, 2009)
"Despite its widespread use, there are many concerns about the efficacy of aspirin in the secondary prevention of cardiovascular events after stroke, leading to the concept of aspirin non-response (ANR)."9.14Stroke and aspirin non-responder patients: relation with hypertension and platelet response to adenosine diphosphate. ( Chomel, JC; Godeneche, G; Macchi, L; Neau, JP; Ragot, S; Sorel, N, 2009)
"To evaluate the relative gastrointestinal (GI) tolerability of celecoxib and rofecoxib in elderly hypertensive patients with osteoarthritis (OA) with or without coadministration of low dose aspirin (ASA) (< or = 325 mg daily)."9.11Cyclooxygenase-2 specific inhibitors and upper gastrointestinal tolerability in patients with osteoarthritis receiving concomitant low dose aspirin: pooled analysis of 2 trials. ( Bello, AE; Fort, JG; Goldstein, JL; Spalding, W; Suh, S, 2005)
"We conducted a subgroup analysis in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study to determine whether aspirin interacted with the properties of losartan, an angiotensin-II receptor antagonist."9.11The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study. ( Dahlöf, B; de Faire, U; Devereux, RB; Edelman, JM; Fossum, E; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Moan, A; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, SM; Wedel, H, 2005)
"COX-2 inhibition with the prodrug, parecoxib, diminishes the acetylcholine-induced vasodilatation in the forearm circulation of patients with essential hypertension."9.10Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension. ( Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A, 2003)
"To assess the tolerability of rofecoxib compared with naproxen for treatment of osteoarthritis."9.10Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial. ( Dixon, ME; Geba, GP; Johansson, G; Lisse, JR; Mollen, AJ; Perlman, M; Polis, AB; Schechtman, J; Shoemaker, JR; Skalky, CS, 2003)
"The objectives of the study were to confirm the validity of using oscillometric measurement of MAP in the left lateral position to identify those at high risk for developing pregnancy-induced hypertension (PIH), and to assess and compare the efficacy of prophylaxis with low-dose aspirin or calcium supplementation in high-risk patients."9.09Calcium and low-dose aspirin prophylaxis in women at high risk of pregnancy-induced hypertension. ( Fung, HY; Hung, CY; Rogers, MS, 1999)
"To analyze determinants of the risk of pregnancy-induced hypertension (PIH) with or without proteinuria, we compared characteristics of women enrolled in the Italian Study of Aspirin in Pregnancy who developed PIH and those who did not."9.08Risk factors for pregnancy-induced hypertension in women at high risk for the condition. Italian Study of Aspirin in Pregnancy Group. ( Benedetto, C; Bortolus, R; Chatenoud, L; Marozio, L; Parazzini, F; Restelli, S; Ricci, E, 1996)
"The aims of this prospective study were to explore the changes in platelet angiotensin II (A-II) binding in pregnancy amongst Chinese women at high risk of developing pregnancy-induced hypertension (PIH) and the effects of low-dose aspirin and calcium supplementation on A-II binding."9.08Platelet angiotensin II receptor status during pregnancy in Chinese women at high-risk of developing pregnancy-induced hypertension. ( Arumanayagam, M; Hung, C; Rogers, MS, 1996)
"We found an association between the addition of ketanserin to aspirin and a decrease in the number of cases of pre-eclampsia and severe hypertension, as well as improved pregnancy outcome among patients with mild to moderate midtrimester hypertension."9.08Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997)
"There are conflicting reports on the interaction of aspirin with angiotensin-converting enzyme inhibitors in heart failure and systemic hypertension."9.08Effects of aspirin on angiotensin-converting enzyme inhibition and left ventricular dilation one year after acute myocardial infarction. ( Anthonio, RL; Crijns, HJ; de Kam, PJ; Kingma, JH; Oosterga, M; van Gilst, WH, 1998)
"Forty-six nulliparous women in third trimester of pregnancy with a raised blood pressure of 30 mm Hg (systolic) or/and 15 mm Hg (diastolic) or both, over baseline values were treated with 75 mg of aspirin per day."9.07A study of use of low dose aspirin in prevention of pregnancy induced hypertension. ( Pan, S; Roy, UK, 1994)
"Effectiveness of early administered low-dose aspirin in prevention of pregnancy-induced hypertension (PIH) and fetal growth retardation in twin pregnancies was investigated in a randomized placebo controlled, double-blind trial in 47 twin pregnancies."9.07Prevention of pregnancy-induced hypertension in twins by early administration of low-dose aspirin: a preliminary report. ( Arieli, S; Bukovski, I; Caspi, E; Raziel, A; Sherman, D; Weinraub, Z, 1994)
" Patients with essential hypertension were treated for 8 weeks with either isradipine focus of double-blind study."9.07Treatment of hypertension with dihydropyridine calcium antagonists and aspirin. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L, 1994)
"To study the effect of daily treatment with 50 mg of aspirin (ASA) on the hypertensive pregnancy complications and on the production prostacyclin (PGI2) and thromboxane A2 (TxA2) in high risk pregnant women and their infants."9.07Low dose aspirin in hypertensive pregnant women: effect on pregnancy outcome and prostacyclin-thromboxane balance in mother and newborn. ( Hartikainen-Sorri, AL; Hiilesmaa, V; Lumme, R; Viinikka, L; Ylikorkala, O, 1993)
" Patients with essential hypertension were treated for 8 weeks with either nitrendipine (10 mg once daily) or isradipine (2."9.07Treatment of hypertension with calcium antagonists and aspirin. Effects on 24-h platelet activity. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Trnovec, T; Ulicna, L, 1993)
"Daily ingestion of 60 mg of aspirin beginning at 24 weeks' gestation significantly reduced the occurrence of preeclampsia."9.07Low-dose aspirin therapy to prevent preeclampsia. ( Copper, RL; Cutter, GR; DuBard, MB; Goldenberg, RL; Hauth, JC; Parker, CR; Philips, JB, 1993)
"Low dose aspirin would appear to be an appropriate agent for the inhibition of platelet reactivity associated with hypertensive pregnancy."9.07A randomized placebo-controlled study of the effect of low dose aspirin on platelet reactivity and serum thromboxane B2 production in non-pregnant women, in normal pregnancy, and in gestational hypertension. ( Broughton Pipkin, F; Fox, S; Heptinstall, S; Louden, KA; Mitchell, JR; O'Callaghan, C; Symonds, EM; Tuohy, P, 1992)
"The effect of low doses of aspirin on women with mild pregnancy-induced hypertension was investigated by means of a prospective, randomized, double-blind trial."9.06Low-dose aspirin does not influence the clinical course of women with mild pregnancy-induced hypertension. ( Barkai, G; Ben-Baruch, G; Mashiach, S; Schiff, E, 1990)
"We carried out a prospective, randomized, double-blind, placebo-controlled study to investigate the capacity of aspirin to prevent pregnancy-induced hypertension and to alter prostaglandin metabolism."9.06The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies. ( Barkai, G; Ben-Baruch, G; Blankstein, J; Goldenberg, M; Peleg, E; Rosenthal, T; Ruppin, E; Schiff, E; Tamarkin, M; Yahal, I, 1989)
"There is evidence that aspirin in low doses favorably influences the course of pregnancy-induced hypertension, but the mechanism, although assumed to involve suppression of the production of thromboxane by platelets, has not been established."9.06Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension. ( Ballerini, S; Benigni, A; Chiabrando, C; Fanelli, R; Frusca, T; Gregorini, G; Orisio, S; Piccinelli, A; Pinciroli, V; Valcamonico, A, 1989)
"The possibility of preventing pregnancy-induced hypertension (PIH) and pre-eclampsia in primigravidae by suppressing production of thromboxane A2 with low-dose aspirin was investigated in a randomised, placebo-controlled, double-blind trial."9.06Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae. ( Dekker, GA; Makovitz, JW; Rotmans, P; Wallenburg, HC, 1986)
"To review the clinical evidence of the effect of aspirin as primary prevention for patients with diabetes mellitus and in healthy elderly."9.05Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly. ( Baliga, RR; Patel, NJ, 2020)
"The study pooled individual data from 2580 participants with nonvalvular AF who were prescribed aspirin in a multicenter trial (Atrial Fibrillation, Aspirin, Anticoagulation I study [AFASAK-1], AFASAK-2, European Atrial Fibrillation Trial, Primary Prevention of Arterial Thromboembolism in patients with nonrheumatic Atrial Fibrillation in primary care study, and Stroke Prevention and Atrial Fibrillation [SPAF]-III high risk or SPAF-III low risk)."8.82Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. ( Boode, BS; Gage, BF; Hart, RG; Koudstaal, PJ; Pearce, L; Petersen, P; van Walraven, C, 2004)
"Results from previous studies indicate that use of aspirin may improve colorectal cancer (CRC) survival."8.31Low-dose aspirin use and colorectal cancer survival in 32,195 patients-A national cohort study. ( Ekström Smedby, K; Glimelius, B; Martling, A; Matthiessen, P; Nordenvall, C; Shahrivar, M; Syk, I; Weibull, CE, 2023)
"To investigate the association between low-dose aspirin use for primary prevention and self-reported kidney stones prevalence in the 40-79 years old population."8.31Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study. ( Chen, Y; Huang, F; Li, Y; Yang, M, 2023)
"Hematoma growth (HG) affects the prognosis of patients with spontaneous intracranial hematoma (ICH), but there is still a lack of evidence about the effects of aspirin (acetylsalicylic acid, ASA) on HG in patients with severe ICH."8.12Aspirin does not affect hematoma growth in severe spontaneous intracranial hematoma. ( Cao, Y; Guo, R; Jiang, P; Liu, Q; Liu, Y; Mo, S; Wang, K; Wang, S; Wu, J; Yang, J; Yang, S; Yang, Y; Zhang, J, 2022)
"Despite the overall association of aspirin on reduced hepatocellular carcinoma (HCC) risk, there have been few studies on its benefit according to specific clinical conditions among hepatitis B virus (HBV)-infected patients."8.12Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study. ( Ahn, SH; Kim, BK; Yoon, JH; Yun, B, 2022)
"To evaluate the accuracy of the EDAN SA-10 oscillometric upper-arm professional office ambulatory blood pressure (BP) monitor in general population according to the Association for the Advancement of Medical Instrumentation (AAMI)/European Society of Hypertension (ESH)/International Organization for Standardization (ISO) Universal Standard (ISO 81060-2:2018)."8.12Validation of the EDAN SA-10 ambulatory blood pressure monitor in general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Universal Stan ( Li, L; Liu, K; Ren, J; Wang, B; Yin, S, 2022)
"Decision tree analysis was created using R software to evaluate four approaches to aspirin prophylaxis in the United States: no aspirin, United States Preventive Service Task Force (USPSTF) with Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) hypertension guidelines, USPSTF with ACC/AHA hypertension guidelines, as well as universal aspirin prophylaxis."8.02The Impact of the New Hypertension Guidelines to Low-Dose Aspirin Prophylaxis Eligibility for the Prevention of Preeclampsia: A Cost-Benefit Analysis. ( Balasooriya, MM; Boscia, AL; Dalkiran, E; Putra, M; Sokol, RJ, 2021)
"Aspirin reduced the risks of MACCE and cancer without increasing the bleeding risk in elderly Koreans with hypertension, T2DM, or dyslipidemia."7.96Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea. ( Jung, M; Lee, S, 2020)
"(1) To evaluate the rates of implementation of the 2016 American College of Obstetricians and Gynecologists guideline over time; and (2) to evaluate the effectiveness of aspirin for the prevention of superimposed preeclampsia and other adverse maternal and neonatal outcomes in women with chronic hypertension before and after this guideline."7.96Impact of the ACOG guideline regarding low-dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension. ( Banala, C; Berghella, V; Boelig, RC; Cruz, Y; Moreno, S; Roman, A; Saccone, G; Schoen, CN, 2020)
"This study aimed to investigate the effectiveness of monotherapy acetylsalicylic acid (ASA) and warfarin for stroke prevention in low-risk atrial fibrillation (AF) by using a population- -based cohort study in Taiwan."7.91Monotherapy of acetylsalicylic acid or warfarin for prevention of ischemic stroke in low-risk atrial fibrillation: A Easter Asian population-based study. ( Chen, HC; Liu, CY, 2019)
"Despite its well-known antithrombotic properties, the effect of aspirin on blood pressure (BP) and hypertension pathology is unclear."7.91Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat. ( Andrews, KL; Chin-Dusting, JPF; Dragoljevic, D; Gaspari, T; Jefferis, AM; Jennings, GL; Khan, SI; Lee, MKS; Moore, XL; Murphy, AJ; Shihata, WA; Vinh, A, 2019)
"We used a single, integrated, microsimulation model to generate comparable results for 3 services recommended by the US Preventive Services Task Force: aspirin counseling for the primary prevention of CVD and colorectal cancer, screening and treatment for lipid disorders (usually high cholesterol), and screening and treatment for hypertension."7.85Health Benefits and Cost-Effectiveness of Asymptomatic Screening for Hypertension and High Cholesterol and Aspirin Counseling for Primary Prevention. ( Dehmer, SP; Flottemesch, TJ; LaFrance, AB; Maciosek, MV, 2017)
"The beneficial effect of aspirin in the prevention of preterm preeclampsia may not apply in pregnancies with chronic hypertension."7.85Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history. ( Akolekar, R; De Stefani, L; Delgado, JL; Evangelinakis, N; Gonzalez-Vanegas, O; Jani, JC; Leipold, G; Nicolaides, KH; Persico, N; Plasencia, W; Poon, LC; Rolnik, DL; Shearing, S; Syngelaki, A; Tsokaki, T; Wright, D, 2017)
"The effect of prior use of aspirin (ASA) on the onset of acute coronary syndrome (ACS) has not been clarified."7.85Association Between Prior Aspirin Use and Morphological Features of Culprit Lesions at First Presentation of Acute Coronary Syndrome Assessed by Optical Coherence Tomography. ( Araki, M; Hada, M; Hamaya, R; Hoshino, M; Ichijo, S; Kakuta, T; Kanaji, Y; Kanno, Y; Lee, T; Matsuda, J; Murai, T; Niida, T; Usui, E; Yonetsu, T, 2017)
"To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia."7.83Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016)
"The US Preventive Services Task Force recommends aspirin use for men aged 45 to 79, when the potential benefit of preventing myocardial infarctions outweighs the potential harm of gastrointestinal hemorrhage."7.81Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013. ( Fleming, E; Perry, GS; Tchwenko, S, 2015)
"Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors."7.80Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid. ( Beckmann, Y; Ciftçi, Y; Seçil, Y; Tokuçoğlu, F, 2014)
" Additional subgroup analysis included the presence of hypertension, diabetes, low-density lipoprotein levels, sex, and use of aspirin."7.79Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study. ( El-Charabaty, E; El-Sayegh, S; Saifan, C, 2013)
"The widespread use of aspirin-driven vascular prevention strategies does not impede the occurrence of first and recurrent ischemic strokes in numerous subjects."7.78Ischemic stroke in patients receiving aspirin. ( Ameriso, S; Ameriso, SF; Povedano, GP; Pujol Lereis, VA, 2012)
"In this retrospective observational study including women with pre-existing hypertension, pre-gestational diabetes or previous placental-mediated complications, we compared the rates of pre-eclampsia, early-onset and severe pre-eclampsia between women who used 81 mg of aspirin (ASA) throughout pregnancy without platelet function analyser (PFA-100®) monitoring ("group ASA no PFA") and those in whom the aspirin dosage was adjusted according to PFA-100® results ("group ASA and PFA")."7.77Is testing for aspirin response worthwhile in high-risk pregnancy? ( Rey, E; Rivard, GE, 2011)
"Cyclo-oxygenase-1 and cyclo-oxygenase-2 deficient mice and their cultured aortic smooth muscle cells were used to investigate the role of these enzymes in angiotensin II induced superoxide production and hypertension."7.77Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension. ( De Champlain, J; Duchemin, S; Girouard, H; Laplante, MA; Wu, R, 2011)
"The regular use of aspirin and non-aspirin analgesics were both associated with an increased risk of developing hypertension, independently of other risk factors."7.76Aspirin, non-aspirin analgesics and the risk of hypertension in the SUN cohort. ( Alonso, A; Bes-Rastrollo, M; Beunza, JJ; Martínez-González, MA; Núñez-Córdoba, JM; Toledo, E, 2010)
"This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive stroke-prone rats (SHRSP)."7.76Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin. ( Ballerio, R; Banfi, C; Blanc-Guillemaud, V; Brioschi, M; Castiglioni, L; Gelosa, P; Gianella, A; Guerrini, U; Lerond, L; Nobili, E; Pignieri, A; Sironi, L; Tremoli, E, 2010)
"A considerable proportion of patients discontinue dipyridamole therapy because of headache."7.75Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin. ( Algra, A; Halkes, PH; Kappelle, LJ; Koudstaal, PJ; van Gijn, J, 2009)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."7.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"To quantify the relative risk of epistaxis for patients taking low-dose aspirin or clopidogrel compared to patients taking neither drug."7.75Clopidogrel versus low-dose aspirin as risk factors for epistaxis. ( Molony, NC; Rainsbury, JW, 2009)
"Aspirin prevented and partially reversed ACTH-induced hypertension in the SD rats."7.74Aspirin prevents and partially reverses adrenocorticotropic hormone-induced hypertension in the rat. ( Miao, Y; Whitworth, JA; Zhang, Y, 2007)
"The aim of this study was to evaluate the relationship of obesity, leptin, insulin resistance and C-reactive protein (CRP) with coronary heart disease (CHD) risk factors in patients with Type 2 diabetes mellitus (DM) with CHD compared with those with Type 2 DM without CHD."7.73Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance. ( Abdella, NA; Al Jebely, S; Al Mohammedi, H; Al Ozairi, ES; Mojiminiyi, OA; Moussa, MA; Zaki, M, 2005)
"A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB."7.73Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease. ( Chen, WH; Cheng, X; Lai, KC; Lam, KF; Lau, CP; Lee, PY; Li, SW; Ng, M; Ng, W; Tse, HF; Wong, WM, 2006)
"Using automatic erythrocyte aggregometer type MA-1 (Myrenne gmbh, Germany), we investigated the hypothesis that therapeutic effectiveness of quinapril--angiotensin converting enzyme inhibitor (ACEI)--in the treatment of hypertension would correlate with improvement of red blood cell (RBC) aggregability."7.72Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension. ( Adamek-Guzik, T; Korbut, R; Korbut, RA; Madej, J, 2003)
"Chronic in vivo treatment with aspirin prevented the development of hypertension and reduced insulin resistance significantly in chronically glucose-fed rats."7.71Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. ( de Champlain, J; El Midaoui, A; Wu, R, 2002)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."7.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
"To determine whether the administration of acetylsalicylic acid (ASA, also known as Aspirin) differentiates patients with renovascular hypertension from those with essential hypertension, in order to provide a simple alternative to more expensive forms of diagnosis for this condition."7.69Acetylsalicylic acid (aspirin) test for the diagnosis of renovascular hypertension. ( Gluszek, J; Gracz, M; Kara-Perz, H; Posadzy-Malaczynska, A; Pupek-Musialik, D; Tykarski, A, 1997)
"To describe patterns of prescription in the Netherlands of low-dose aspirin in pregnancy."7.68Low-dose aspirin in pregnancy: changes in patterns of prescription in The Netherlands. ( Bremer, HA; Wallenburg, HC, 1993)
"Low dose Aspirin in pregnancy reduces the incidence of intra uterine growth retardation (IUGR) and pregnancy induced hypertension (PIH) in women at risk for these complications."7.68Low dose aspirin in pregnancy: a clinical and biochemical study of effects on the newborn. ( Foschini, M; Frusca, T; Soregaroli, M; Tarantini, M; Valcamonico, A, 1993)
"Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT)."7.68Aspirin test for differentiation of unilateral renovascular hypertension from hyperreninemic essential hypertension. ( Akabane, S; Imanishi, M; Ito, K; Kawamura, M; Kimura, K; Kojima, S; Kuramochi, M; Matsushima, Y; Ohta, M; Takamiya, M, 1991)
"Urinary excretion of thromboxane B2 metabolites as markers of thromboxane A2 synthesis was measured in eight patients with moderate to severe pregnancy-induced hypertension and in six normotensive pregnant women at term."7.68Thromboxane A2 synthesis in pregnancy-induced hypertension. ( Fitzgerald, DJ; FitzGerald, GA; Mayo, G; Murray, R; Rocki, W, 1990)
"A mode of interaction of bradykinin with prostaglandins (PGs) in pain were compared with that in acute inflammation."7.67Different modes of interaction of bradykinin with prostaglandins in pain and acute inflammation. ( Harada, Y; Hori, Y; Katori, M; Tanaka, K; Uchida, Y, 1986)
"The ability of platelets to synthesize thromboxane B2 (TxB2) from arachidonic acid (AA) or prostaglandin H2 (PGH2) was studied in 26 control subjects, 40 patients with essential hypertension, 20 patients with cerebrovascular disease (CVD) not taking aspirin and 11 patients with CVD taking aspirin."7.66Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. ( Imaizumi, M; Kayama, N; Matsumoto, M; Miyamoto, T; Nukada, T; Uyama, O; Yoneda, S, 1980)
"The results of two large independent studies involving a combined total of 776 patients treated in hospital with a discharge diagnosis of acute myocardial infarction and 13,898 patients with other discharge diagnoses showed a negative association between regular aspirin intake and non-fatal myocardial infarction."7.65Regular aspirin intake and acute myocardial infarction. ( , 1974)
"Preeclampsia is a hypertensive disorder of pregnancy affecting up to 8% of pregnancies."7.01Aspirin and Pravastatin for Preeclampsia Prevention in High-Risk Pregnancy. ( Costantine, MM; Eid, J; Rood, KM, 2023)
"Aspirin was not found to substantially diminish the risk of incidence of preeclampsia, but it did show some beneficial effects."7.01Role of aspirin in the prevention of preeclampsia in previously hypertensive pregnant women: A Meta-Analysis. ( Ashraf Jahangeer, SM; Khan, AA; Mansoor, M, 2023)
"The rate of superimposed preeclampsia was 28."6.79Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial. ( Atallah, AN; Kulay, L; Santos, GM; Sass, N; Souza, EV; Torloni, MR, 2014)
"Aspirin resistance was defined as having a closure time (CT) of <186 s with Col/Epi cartridges despite regular aspirin therapy."6.74Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease. ( Nisanci, Y; Oflaz, H; Pamukcu, B; Tirnaksiz, E, 2009)
"We examined the prevalence and medical treatment of hypertension among 15,904 ACS patients randomized in the SYMPHONY and 2nd SYMPHONY trials."6.71Prevalence and management of hypertension in acute coronary syndrome patients varies by sex: observations from the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes (SYMPHONY) randomized clinical ( Armstrong, PW; Aylward, PE; Bhapkar, MV; Frazier, CG; Klein, WW; Kristinsson, A; McGuire, DK; Newby, LK; Sadowski, Z; Shah, SH; Weaver, WD, 2005)
"Essential hypertension is one of the most important risk factors for cardiovascular diseases."6.70[The effect of aspirin on rheological properties of erythrocytes in essential hypertension]. ( Adamek-Guzik, T; Korbut, RA, 2002)
"Whether low-dose aspirin prevents preeclampsia is unclear."6.69Low-dose aspirin to prevent preeclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, S; Hauth, J; Klebanoff, M; Landon, M; Lindheimer, MD; Meis, P; Miodovnik, M; Paul, R; Sibai, B; Thom, E; Thurnau, G; VanDorsten, P, 1998)
" In conclusion, treatment with dihydropyridines alone or in combination with low-dose aspirin can prevent circadian increases in platelet activity in patients with essential hypertension."6.67Effects of dihydropyridines and their combination with aspirin on blood pressure and circadian platelet activity in patients with essential hypertension. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L, 1994)
"The incidence of preeclampsia was lower in the aspirin group (69 of 1485 women [4."6.67Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, SN; Klebanoff, M; McNellis, D; Paul, RH; Rocco, L; Romero, R; Rosen, M; Sibai, BM; Thom, E; Witter, F, 1993)
"Chronic hypertension affects 1-5% of women of childbearing age."6.66Aspirin for the prevention of placenta-mediated complications in pregnant women with chronic hypertension. ( Haddad, B; Lecarpentier, E, 2020)
"Aspirin has been shown to acutely block the natriuretic effect of spironolactone in the mineralocorticoid-treated normal rat, dog, and man."6.64Failure of aspirin to antagonize the antihypertensive effect of spironolactone in low-renin hypertension. ( Hollifield, JW, 1976)
"Preeclampsia is a hypertensive disorder of pregnancy that remains a significant cause of maternal morbidity and mortality worldwide."6.53Aspirin vs Heparin for the Prevention of Preeclampsia. ( Kanellopoulou, T; Katsi, V; Makris, T; Nihoyannopoulos, P; Nomikou, E; Tousoulis, D, 2016)
" All patients were randomly assigned to take aspirin 75 mg/day or placebo, and patients in the aspirin group had a 15% lower rate of major cardiovascular events and myocardial infarctions than did patients who received placebo."6.19Aggressive blood pressure lowering is safe, but benefit is still hard to prove. ( Pohl, MA; Vidt, DG, 1999)
"To explore the ATF2 expression of preeclampsia patients and investigate whether the level of ATF2 expression impacted the low-dose aspirin treatment of preeclampsia patients."5.91Low-dose Aspirin may Prevent Preeclampsia by Inhibiting the Expression of ATF2. ( Guo, L; Hu, R; Liu, R; Xiao, S; Zhang, M, 2023)
"These findings suggest that individuals with twin pregnancies, a history of preeclampsia, or hypertension may not benefit from aspirin to the same extent as those with other complications such as obesity or diabetes."5.69Persisting risk factors for preeclampsia among high-risk pregnancies already using prophylactic aspirin: a multi-country retrospective investigation. ( Corsi, DJ; Dagvadorj, A; Dingwall-Harvey, ALJ; El-Chaár, D; Gaudet, LM; Guo, Y; McLean, C; Muldoon, KA; Rennicks White, R; Rybak, N; Walker, MC; Wen, SW, 2023)
"Ticagrelor-aspirin was associated with reduced risk of new stroke in patients without hypertension (32 [4."5.51Effect of Hypertension on Efficacy and Safety of Ticagrelor-Aspirin Versus Clopidogrel-Aspirin in Minor Stroke or Transient Ischemic Attack. ( Bath, PM; Chen, G; Huang, P; Jiang, Y; Jing, J; Johnston, SC; Li, H; Li, Z; Lin, J; Liu, L; Meng, X; Tian, X; Wang, A; Wang, F; Wang, Y; Xie, X; Zhao, X; Zuo, Y, 2022)
"This study was to study the efficacy of rosuvastatin, amlodipine, and aspirin in the treatment of hypertension with coronary heart disease and its effect on platelet aggregation."5.51The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation. ( Fu, J; Li, B; Wang, T; Zhao, N, 2022)
"The cohort of women with a history of preeclampsia were divided into 2 groups, before and after the release of the US Preventive Services Task Force 2014 recommendations."5.46Impact of USPSTF recommendations for aspirin for prevention of recurrent preeclampsia. ( Aagaard, KM; Chu, DM; Hollier, LM; Mastrobattista, JM; Racusin, DA; Ramin, SM; Sangi-Haghpeykar, H; Tolcher, MC, 2017)
"This systematic review and meta-analysis investigated whether the use of low-dose aspirin during pregnancy by women with chronic hypertension reduces the odds of superimposed preeclampsia and poor perinatal outcomes."5.41Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis. ( Giorgione, V; Richards, EMF; Stevens, O; Thilaganathan, B, 2023)
"Recent studies have shown a benefit to more aggressive treatment of mild chronic hypertension to a blood pressure goal of <140/90 with oral labetalol and nifedipine remaining first-line agents."5.41Cardiac medications in obstetric patients. ( Albert-Stone, E; Davis, MB; Spehar, SM, 2023)
"The aim of the study is to evaluate the effects of supplementation with Arginine (L-Arg) 3g, (together with Magnesium (Mg) 350 mg and Salicilate (Sal) 100 mg) on maternal blood pressure (BP), uterine artery doppler PI and neonatal outcomes in women with high-risk pregnancy for chronic hypertension (CH) and other previous placenta vascular disorders (PVD) already treated with low dose of aspirin (LDA), as recommended by guidelines."5.41Effect of L-arginine supplementation in pregnant women with chronic hypertension and previous placenta vascular disorders receiving Aspirin prophylaxis: a randomized control trial. ( Basile, L; Facchinetti, F; Menichini, D; Monari, F; Neri, I; Pignatti, L, 2021)
"Aspirin resistance was detected in 22 (16."5.40Hypertension as a risk factor for aspirin and clopidogrel resistance in patients with stable coronary artery disease. ( Akturk, IF; Caglar, FN; Caglar, IM; Erturk, M; Surgit, O; Tuncer, N; Uzun, F; Yalcın, AA, 2014)
"Hypertension is the most important modifiable risk factor for intracerebral hemorrhage (ICH), but blood pressure (BP) management during the acute phase of ICH is still controversial."5.38The effect of admission blood pressure on the prognosis of patients with intracerebral hemorrhage that occurred during treatment with aspirin, warfarin, or no drugs. ( Asil, T; Balci, K; Celik, Y; Ir, N; Tekinaslan, I; Unlu, E; Utku, U, 2012)
"This study aimed to evaluate the maternal and fetal results in women undergoing antihypertensive therapy (low aspirin or labetalol) with mild to severe chronic hypertension relative to women without medicines."5.34Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo. ( Wang, F; Xiang, X; Zhao, N; Zhou, Z, 2020)
"Rofecoxib also reduced cardiac hypertrophy."5.33Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005)
" We evaluated preconception blood pressure and fecundability, pregnancy loss, and live birth in the EAGeR trial (Effects of Aspirin on Gestational and Reproduction; 2007-2011), a randomized clinical trial of aspirin and reproductive outcomes among 1228 women attempting pregnancy with a history of pregnancy loss."5.27Preconception Blood Pressure Levels and Reproductive Outcomes in a Prospective Cohort of Women Attempting Pregnancy. ( Kim, K; Mendola, P; Mumford, SL; Naimi, AI; Nobles, CJ; Park, H; Perkins, NJ; Schisterman, EF; Silver, RM; Sjaarda, L; Wilcox, B; Yeung, EH, 2018)
"Clinical studies results show that policosanol (20 mg/day) + aspirin therapy had benefits versus placebo + aspirin to patients with recent non-cardioembolic ischemic stroke."5.27Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients. ( Fernandez-Dorta, L; Fernandez-Travieso, JC; Illnait-Ferrer, J; Mas-Ferreiro, R; Mendoza-Castano, S; Mesa-Angarica, M; Reyes-Suarez, P; Sanchez-Lopez, J, 2018)
" One study (CAPRIE; ASA versus clopidogrel) included patients diagnosed with hypertension (mean age 62."5.22Antiplatelet agents and anticoagulants for hypertension. ( Kozieł-Siołkowska, M; Lip, GY; Shantsila, E, 2022)
"A total of 14 464 patients (age, 60-85 years) with hypertension, dyslipidemia, and diabetes mellitus participated and were randomized into 2 treatment groups: 100 mg of aspirin or no aspirin."5.22Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project. ( Ando, K; Ikeda, Y; Ishizuka, N; Matsumoto, M; Minematsu, K; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2016)
"We investigated the effects of oral administration of enteric coated aspirin (ASA) on blood pressure and blood pressure variability of hypertension patients before sleep."5.22Clinical study on influences of enteric coated aspirin on blood pressure and blood pressure variability. ( Chen, WW; Huang, WJ; Ji, AL, 2016)
"The aim of this study is to analyze the effect of 100 mg/d regular oral intake of aspirin during pregnancy on high-risk pregnancy-induced hypertension syndrome patients."5.22Effect of regular oral intake of aspirin during pregnancy on pregnancy outcome of high-risk pregnancy-induced hypertension syndrome patients. ( Li, L; Liu, FM; Wang, M; Yang, HL; Zhao, M, 2016)
"213 patients with type 2 diabetes mellitus and hypertension were randomized to amlodipine 5 mg, or amlodipine 5 mg + ASA 100 mg for 3 months (Phase A); then, if adequate blood pressure control was reached patients terminated the study; otherwise, amlodipine was up-titrated to 10 mg/day for further 3 months and compared to amlodipine 10 mg + ASA 100 mg (Phase B)."5.20A study about the relevance of adding acetylsalicylic acid in primary prevention in subjects with type 2 diabetes mellitus: effects on some new emerging biomarkers of cardiovascular risk. ( D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM, 2015)
"Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors."5.19Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial. ( Ando, K; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2014)
" In the present retrospective analysis of the randomized, double-blind, parallel-group, SMILE-4 study we compared the efficacy of zofenopril 60 mg and acetylsalicylic acid (ASA) 100 mg versus ramipril 10 mg and ASA in patients with AMI complicated by left ventricular dysfunction, classified according to a history of hypertension."5.17Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study. ( Ambrosio, G; Ambrosioni, E; Bacchelli, S; Borghi, C; Cicero, AF; Esposti, DD; Omboni, S; Vinereanu, D; Zava, D, 2013)
"The objective of this study is to evaluate the antihypertensive effect of bedtime administration of low doses of aspirin in patients with treated hypertension and high cardiovascular risk on low-dose aspirin for secondary prevention, in order to optimize their usual treatment and reduce their cardiovascular risk."5.17Protocol for assessing the hypotensive effect of evening administration of acetylsalicylic acid: study protocol for a randomized, cross-over controlled trial. ( Burgos-Alonso, N; Fernández, MC; Grandes, G; Ruíz-Arzalluz, MV; San Vicente Blanco, R; Vinyoles, E, 2013)
"It does not appear useful to advise patients with long-standing hypertension to modify timing of aspirin intake in order to reduce BP values."5.16Is there a BP benefit of changing the time of aspirin administration in treated hypertensive patients? ( Baguet, JP; Dimitrov, Y; Ducher, M; Fauvel, JP; Hottelart, C; Marboeuf, P; Tartiere, JM, 2012)
"We identified 9 independent risk factors for SICH: baseline National Institutes of Health Stroke Scale, serum glucose, systolic blood pressure, age, body weight, stroke onset to treatment time, aspirin or combined aspirin and clopidogrel, and history of hypertension."5.16Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score. ( Ahmed, N; Egido, JA; Ford, GA; Lees, KR; Mazya, M; Mikulik, R; Toni, D; Wahlgren, N, 2012)
"TAIST was a randomized controlled trial assessing 10 days of treatment with tinzaparin versus aspirin in 1489 patients with acute ischemic stroke (<48 hr) with admission BP of 5.14The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the tinzaparin in acute ischaemic stroke trial (TAIST). ( Bath, PM; Christensen, H; De Deyn, PP; England, T; Geeganage, C; Gray, LJ; Leys, D; Moulin, T; O'Neill, D; Ringelstein, EB; Sare, GM; Woimant, F, 2009)
"In a laboratory substudy of the PRAGUE-8 trial, the influences of nonmodifiable (age and sex) and modifiable (body mass index and tobacco smoke) factors, comorbidity (hypertension, hyperlipidemia, diabetes mellitus, and renal insufficiency) and cotherapy (statin, aspirin, and heparin), on the course of clopidogrel efficacy were investigated in 105 patients pretreated with clopidogrel >or=6 hours before coronary angiography +/- percutaneous coronary intervention."5.14Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox". ( Bilkova, D; Kala, P; Marinov, I; Motovska, Z; Petr, R; Simek, S; Widimsky, P, 2009)
"The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study is an international double-blind, randomized controlled trial designed to investigate the superiority of the specific TP receptor antagonist terutroban (30 mg/day) over aspirin (100 mg/day), in reducing cerebrovascular and cardiovascular events in patients with a recent history of ischemic stroke or transient ischemic attack."5.14The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study: baseline characteristics of the population. ( Amarenco, P; Bousser, MG; Chamorro, A; Fisher, M; Ford, I; Fox, K; Hennerici, M; Mattle, HP; Rothwell, PM, 2009)
"Aspirin has been found to prevent angiotensin II-induced hypertension and to induce nitric oxide (NO) release from vascular endothelium."5.14Ambulatory blood pressure control with bedtime aspirin administration in subjects with prehypertension. ( Ayala, DE; Fernández, JR; Hermida, RC; Mojón, A, 2009)
" A total of 154 untreated hypertensive patients, aged 40 to 66 years, with World Health Organization stage I or II hypertension and left ventricular hypertrophy, were randomized to receive placebo, candesartan (32 mg), each of these plus aspirin (300 mg/d), or the same preparations in a reverse order, for 3 weeks, with a 3-week washout period between treatments."5.14Candesartan improves maximal exercise capacity in hypertensives: results of a randomized placebo-controlled crossover trial. ( Chiariello, M; De Rosa, ML, 2009)
"Despite its widespread use, there are many concerns about the efficacy of aspirin in the secondary prevention of cardiovascular events after stroke, leading to the concept of aspirin non-response (ANR)."5.14Stroke and aspirin non-responder patients: relation with hypertension and platelet response to adenosine diphosphate. ( Chomel, JC; Godeneche, G; Macchi, L; Neau, JP; Ragot, S; Sorel, N, 2009)
"The Japanese Primary Prevention Project (JPPP) is a multicenter, open-label, randomized, parallel-group trial that is evaluating primary prevention with low-dose aspirin in Japanese patients aged 60 to 85 years with hypertension, dyslipidemia, or diabetes mellitus."5.14Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events. ( Ando, K; Goto, Y; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamada, N; Yamazaki, T; Yokoyama, K, 2010)
"The HOT (Hypertension Optimal Treatment) study randomly assigned participants with diastolic hypertension to aspirin (75 mg) or placebo."5.14Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial. ( Cass, A; Chalmers, J; Gallagher, MP; Jardine, MJ; Lambers Heerspink, HJ; Ninomiya, T; Perkovic, V; Turnbull, F; Zanchetti, A; Zoungas, S, 2010)
"To evaluate the relative gastrointestinal (GI) tolerability of celecoxib and rofecoxib in elderly hypertensive patients with osteoarthritis (OA) with or without coadministration of low dose aspirin (ASA) (< or = 325 mg daily)."5.11Cyclooxygenase-2 specific inhibitors and upper gastrointestinal tolerability in patients with osteoarthritis receiving concomitant low dose aspirin: pooled analysis of 2 trials. ( Bello, AE; Fort, JG; Goldstein, JL; Spalding, W; Suh, S, 2005)
"The main objective of this study was to assess whether aspirin 100 mg QD can improve blood pressure (BP) control and endothelial function in subjects with arterial hypertension (AH) and hypercholesterolaemia."5.11Effects of low-dose aspirin on blood pressure and endothelial function of treated hypertensive hypercholesterolaemic subjects. ( London, D; Magen, E; Mishal, J; Priluk, R; Viskoper, JR; Yosefy, C, 2005)
"Aspirin is a potent antioxidative agent that reduces vascular production of superoxide, prevents angiotensin II-induced hypertension, and induces NO release."5.11Differing administration time-dependent effects of aspirin on blood pressure in dipper and non-dipper hypertensives. ( Ayala, DE; Calvo, C; Fernández, JR; Hermida, RC; López, JE; Mojón, A; Rodríguez, M, 2005)
"We conducted a subgroup analysis in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study to determine whether aspirin interacted with the properties of losartan, an angiotensin-II receptor antagonist."5.11The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study. ( Dahlöf, B; de Faire, U; Devereux, RB; Edelman, JM; Fossum, E; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Moan, A; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, SM; Wedel, H, 2005)
"Effectiveness of a prolonged form of diltiazem was studied in 20 patients with stable effort angina and chronic cardiac failure (NYHA functional class II)."5.10[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure]. ( Gadzhiev, AN, 2002)
"COX-2 inhibition with the prodrug, parecoxib, diminishes the acetylcholine-induced vasodilatation in the forearm circulation of patients with essential hypertension."5.10Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension. ( Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A, 2003)
"To assess the tolerability of rofecoxib compared with naproxen for treatment of osteoarthritis."5.10Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial. ( Dixon, ME; Geba, GP; Johansson, G; Lisse, JR; Mollen, AJ; Perlman, M; Polis, AB; Schechtman, J; Shoemaker, JR; Skalky, CS, 2003)
" the level of blood pressure associated with the lowest incidence of major cardiovascular events such as fatal and non-fatal stroke and myocardial infarction and other cardiovascular mortality); and (2) to assess the effect of a low dose of acetylsalicylic acid (aspirin) compared with placebo on major cardiovascular events."5.09The Hypertension Optimal Treatment study and the importance of lowering blood pressure. ( Hansson, L, 1999)
"The objectives of the study were to confirm the validity of using oscillometric measurement of MAP in the left lateral position to identify those at high risk for developing pregnancy-induced hypertension (PIH), and to assess and compare the efficacy of prophylaxis with low-dose aspirin or calcium supplementation in high-risk patients."5.09Calcium and low-dose aspirin prophylaxis in women at high risk of pregnancy-induced hypertension. ( Fung, HY; Hung, CY; Rogers, MS, 1999)
"This was a prospective observation of pregnancy outcomes among 462 women with pregestational diabetes mellitus (White classes B-F) and singleton pregnancies who were enrolled in a multicenter trial to compare low-dose aspirin with placebo for preeclampsia prevention."5.09Risks of preeclampsia and adverse neonatal outcomes among women with pregestational diabetes mellitus. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, S; Dombrowski, M; Hauth, J; Klebanoff, M; Landon, M; Lindheimer, M; MacPherson, C; McNellis, D; Meis, P; Miodovnik, M; Paul, R; Roberts, J; Sibai, BM; Thurnau, G; VanDorsten, JP, 2000)
"0001) after adjustment for age, aspirin use, smoking, physical activity, body mass index, and history of angina, hypertension, and high cholesterol."5.09Alcohol consumption and risk of coronary heart disease by diabetes status. ( Ajani, UA; Buring, JE; Gaziano, JM; Hennekens, CH; Liu, S; Lotufo, PA; Manson, JE, 2000)
"To analyze determinants of the risk of pregnancy-induced hypertension (PIH) with or without proteinuria, we compared characteristics of women enrolled in the Italian Study of Aspirin in Pregnancy who developed PIH and those who did not."5.08Risk factors for pregnancy-induced hypertension in women at high risk for the condition. Italian Study of Aspirin in Pregnancy Group. ( Benedetto, C; Bortolus, R; Chatenoud, L; Marozio, L; Parazzini, F; Restelli, S; Ricci, E, 1996)
"The aims of this prospective study were to explore the changes in platelet angiotensin II (A-II) binding in pregnancy amongst Chinese women at high risk of developing pregnancy-induced hypertension (PIH) and the effects of low-dose aspirin and calcium supplementation on A-II binding."5.08Platelet angiotensin II receptor status during pregnancy in Chinese women at high-risk of developing pregnancy-induced hypertension. ( Arumanayagam, M; Hung, C; Rogers, MS, 1996)
"We found an association between the addition of ketanserin to aspirin and a decrease in the number of cases of pre-eclampsia and severe hypertension, as well as improved pregnancy outcome among patients with mild to moderate midtrimester hypertension."5.08Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia. ( Odendaal, HJ; Steyn, DW, 1997)
"There are conflicting reports on the interaction of aspirin with angiotensin-converting enzyme inhibitors in heart failure and systemic hypertension."5.08Effects of aspirin on angiotensin-converting enzyme inhibition and left ventricular dilation one year after acute myocardial infarction. ( Anthonio, RL; Crijns, HJ; de Kam, PJ; Kingma, JH; Oosterga, M; van Gilst, WH, 1998)
"We studied 2503 women with either diabetes mellitus, chronic hypertension, multifetal gestation, or pre-eclampsia in a previous pregnancy who participated in a multicenter study comparing aspirin and placebo in preventing pre-eclampsia."5.08Predictors of pre-eclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, S; Dombrowski, M; Hauth, J; Klebanoff, M; Landon, M; Lindheimer, M; McNellis, D; Meis, P; Miodovnik, M; Paul, R; Roberts, J; Sibai, B; Thom, E; Thurnau, G; VanDorsten, P, 1998)
"Forty-six nulliparous women in third trimester of pregnancy with a raised blood pressure of 30 mm Hg (systolic) or/and 15 mm Hg (diastolic) or both, over baseline values were treated with 75 mg of aspirin per day."5.07A study of use of low dose aspirin in prevention of pregnancy induced hypertension. ( Pan, S; Roy, UK, 1994)
" 10 with mild uncomplicated and untreated essential hypertension, 10 with essential hypertension under chronic treatment with captopril, 50 mg bid, and 10 with essential hypertension under chronic treatment with atenolol, 100 mg oid, received aspirin, 100 mg oid, and the corresponding placebo for one month, according to a double blind randomized cross-over design."5.07Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients. ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A; Taddei, S, 1994)
"Effectiveness of early administered low-dose aspirin in prevention of pregnancy-induced hypertension (PIH) and fetal growth retardation in twin pregnancies was investigated in a randomized placebo controlled, double-blind trial in 47 twin pregnancies."5.07Prevention of pregnancy-induced hypertension in twins by early administration of low-dose aspirin: a preliminary report. ( Arieli, S; Bukovski, I; Caspi, E; Raziel, A; Sherman, D; Weinraub, Z, 1994)
"Concern has been expressed about possible neonatal side effects after the use of maternal anti-platelet agents in pregnancy, particularly low dose aspirin treatment."5.07Neonatal platelet reactivity and serum thromboxane B2 production in whole blood: the effect of maternal low dose aspirin. ( Broughton Pipkin, F; Fox, SC; Heptinstall, S; Louden, KA; Mitchell, JR; O'Callaghan, C; Symonds, EM; Tuohy, P, 1994)
" Patients with essential hypertension were treated for 8 weeks with either isradipine focus of double-blind study."5.07Treatment of hypertension with dihydropyridine calcium antagonists and aspirin. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L, 1994)
"To study the effect of daily treatment with 50 mg of aspirin (ASA) on the hypertensive pregnancy complications and on the production prostacyclin (PGI2) and thromboxane A2 (TxA2) in high risk pregnant women and their infants."5.07Low dose aspirin in hypertensive pregnant women: effect on pregnancy outcome and prostacyclin-thromboxane balance in mother and newborn. ( Hartikainen-Sorri, AL; Hiilesmaa, V; Lumme, R; Viinikka, L; Ylikorkala, O, 1993)
" Patients with essential hypertension were treated for 8 weeks with either nitrendipine (10 mg once daily) or isradipine (2."5.07Treatment of hypertension with calcium antagonists and aspirin. Effects on 24-h platelet activity. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Trnovec, T; Ulicna, L, 1993)
"Daily ingestion of 60 mg of aspirin beginning at 24 weeks' gestation significantly reduced the occurrence of preeclampsia."5.07Low-dose aspirin therapy to prevent preeclampsia. ( Copper, RL; Cutter, GR; DuBard, MB; Goldenberg, RL; Hauth, JC; Parker, CR; Philips, JB, 1993)
"In a prospective, randomized, double-blind study for the prevention of pregnancy-induced hypertension and preeclampsia, 41 primigravidae with positive roll-over test (28th-32nd week of pregnancy) received 80 mg aspirin/day or placebo until the end of the 37th week."5.07Low-dose aspirin in primigravidae with positive roll-over test. ( Alge, A; Dapunt, O; Daxenbichler, G; Hansen, H; Pastner, E; Schröcksnadel, H; Schwegel, P; Sitte, B; Steckel-Berger, G, 1992)
"Low dose aspirin would appear to be an appropriate agent for the inhibition of platelet reactivity associated with hypertensive pregnancy."5.07A randomized placebo-controlled study of the effect of low dose aspirin on platelet reactivity and serum thromboxane B2 production in non-pregnant women, in normal pregnancy, and in gestational hypertension. ( Broughton Pipkin, F; Fox, S; Heptinstall, S; Louden, KA; Mitchell, JR; O'Callaghan, C; Symonds, EM; Tuohy, P, 1992)
"The effect of low doses of aspirin on women with mild pregnancy-induced hypertension was investigated by means of a prospective, randomized, double-blind trial."5.06Low-dose aspirin does not influence the clinical course of women with mild pregnancy-induced hypertension. ( Barkai, G; Ben-Baruch, G; Mashiach, S; Schiff, E, 1990)
"We carried out a prospective, randomized, double-blind, placebo-controlled study to investigate the capacity of aspirin to prevent pregnancy-induced hypertension and to alter prostaglandin metabolism."5.06The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies. ( Barkai, G; Ben-Baruch, G; Blankstein, J; Goldenberg, M; Peleg, E; Rosenthal, T; Ruppin, E; Schiff, E; Tamarkin, M; Yahal, I, 1989)
"There is evidence that aspirin in low doses favorably influences the course of pregnancy-induced hypertension, but the mechanism, although assumed to involve suppression of the production of thromboxane by platelets, has not been established."5.06Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension. ( Ballerini, S; Benigni, A; Chiabrando, C; Fanelli, R; Frusca, T; Gregorini, G; Orisio, S; Piccinelli, A; Pinciroli, V; Valcamonico, A, 1989)
"The possibility of preventing pregnancy-induced hypertension (PIH) and pre-eclampsia in primigravidae by suppressing production of thromboxane A2 with low-dose aspirin was investigated in a randomised, placebo-controlled, double-blind trial."5.06Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae. ( Dekker, GA; Makovitz, JW; Rotmans, P; Wallenburg, HC, 1986)
"To review the clinical evidence of the effect of aspirin as primary prevention for patients with diabetes mellitus and in healthy elderly."5.05Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly. ( Baliga, RR; Patel, NJ, 2020)
"In postmyocardial infarction patients longterm aspirin treatment with 1."5.05Does chronic aspirin treatment increase blood pressure in man? ( Kaufmann, W; Oster, P; Walter, E, 1981)
"Aspirin reduces the risk of nonfatal myocardial infarction and stroke, and the risk of colorectal cancer."4.95Aspirin for Primary Prevention. ( Owens, DK; Richman, IB, 2017)
" Low-dose aspirin and calcium were identified as candidates for a polypill, with risk reduction estimations for pregnancy-induced hypertension and preeclampsia ranging between 10 and 62 %, depending on patient population characteristics including a priori risk, and gestation age at start of intervention."4.93Prevention of Hypertensive Disorders of Pregnancy: a Novel Application of the Polypill Concept. ( Browne, JL; Franx, A; Grobbee, DE; Klipstein-Grobusch, K, 2016)
"Risk prediction models may be valuable to identify women at risk of pre-eclampsia to guide aspirin prophylaxis in early pregnancy."4.93The performance of risk prediction models for pre-eclampsia using routinely collected maternal characteristics and comparison with models that include specialised tests and with clinical guideline decision rules: a systematic review. ( Al-Rubaie, Z; Askie, LM; Hudson, HM; Lord, SJ; Ray, JG, 2016)
" Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in addition to regular 75 mg aspirin which virtually abolished post-operative thromboembolic stroke and may also have contributed towards a decline in stroke/death following major cardiac events; and (iii) the provision of written guidance for managing post-CEA hypertension which was associated with virtual abolition of intracranial haemorrhage and stroke as a result of hyperperfusion syndrome."4.89Closing the loop: a 21-year audit of strategies for preventing stroke and death following carotid endarterectomy. ( Bell, PR; Bown, MJ; Dennis, MJ; London, NJ; McCarthy, MJ; Nasim, A; Naylor, AR; Sayers, RD, 2013)
" Zofenopril proved to be very effective in patients with coronary artery disease and myocardial infarction, thanks to its unique effective mechanism of action for improving blood pressure control, left ventricular function and myocardial ischemia burden, as well as angiotensin-converting enzyme inhibition."4.88Long-term clinical experience with zofenopril. ( Bacchelli, S; Borghi, C; Degli Esposti, D, 2012)
" Surprisingly, it has been suggested recently that aspirin lowers blood pressure and could be used for preventing hypertension."4.86Antihypertensive effects of aspirin: what is the evidence? ( Bautista, LE; Vera, LM, 2010)
" The ratios of RRs comparing the benefit of aspirin among patients with diabetes compared with patients without diabetes for mortality, myocardial infarction, and ischemic stroke were 1."4.85Aspirin for the primary prevention of cardiovascular events: a systematic review and meta-analysis comparing patients with and without diabetes. ( Aggarwal, NR; Albuquerque, FN; Calvin, AD; Elamin, MB; Erwin, PJ; Fernandez-Balsells, MM; Geske, JB; Lampropulos, JF; Montori, VM; Murad, MH; Shi, Q; Smith, SA, 2009)
" We used the search terms metabolic syndrome, abdominal obesity, waist circumference, insulin resistance, cardiovascular disease, prediabetes, diabetes, treatment, prevention, aspirin, hypertension, cholesterol, atherogenic dyslipidemia, lifestyle therapy, diet, and exercise."4.84A practical "ABCDE" approach to the metabolic syndrome. ( Bansal, S; Blaha, MJ; Blumenthal, RS; Defilippis, AP; Golden, SH; Rouf, R, 2008)
" The CHADS2 risk-stratification scheme, based on a clinical history of heart failure, hypertension, age >75, diabetes, or prior stroke, is a useful clinical tool to identify patients likely to benefit from warfarin, distinguishing these patients from patients at lower risk for whom aspirin is sufficient."4.84Confronting atrial fibrillation in the elderly: stroke risk stratification and emerging antithrombotic therapies. ( Halperin, JL; Strong, SH, 2007)
" Increased leptin, dysregulation of adipocyte proteins, increased insulin resistance and C-reactive protein may be factors involved in the increased incidence of cardiovascular morbidity and mortality directly related to obesity."4.83Stroke prevention in diabetes and obesity. ( Govindarajan, G; Kurukulasuriya, LR; Sowers, J, 2006)
" Over the 10 to 15 years after clinical diagnosis, tight glycemic control probably reduces the risk for blindness and end-stage renal disease, and aggressive control of hypertension, lipid therapy, and aspirin use reduce cardiovascular events."4.82Screening adults for type 2 diabetes: a review of the evidence for the U.S. Preventive Services Task Force. ( Donahue, K; Frame, P; Harris, R; Lohr, KN; Rathore, SS; Woolf, SH, 2003)
", statins), and aspirin therapy for the primary prevention of coronary heart disease (CHD) in an elderly patient population (age >or=65 y)."4.82Primary prevention of coronary heart disease in the elderly. ( Dornbrook-Lavender, KA; Pieper, JA; Roth, MT, 2003)
"The results of the VIGOR study that demonstrated an increase in risk of myocardial infarction with rofecoxib, can probably be explained by an anti-thrombotic effect of naproxene, the high dose of rofecoxib used, the type of patients included or the fact that aspirin had been contraindicated."4.82[Renal and cardiovascular effects of non-steroidal anti-inflammatories and selective cox 2 inhibitors]. ( Deray, G, 2004)
"The study pooled individual data from 2580 participants with nonvalvular AF who were prescribed aspirin in a multicenter trial (Atrial Fibrillation, Aspirin, Anticoagulation I study [AFASAK-1], AFASAK-2, European Atrial Fibrillation Trial, Primary Prevention of Arterial Thromboembolism in patients with nonrheumatic Atrial Fibrillation in primary care study, and Stroke Prevention and Atrial Fibrillation [SPAF]-III high risk or SPAF-III low risk)."4.82Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. ( Boode, BS; Gage, BF; Hart, RG; Koudstaal, PJ; Pearce, L; Petersen, P; van Walraven, C, 2004)
"The use of low doses of aspirin on a daily basis has increased greatly in the past 20 years, based on observations that it can significantly reduce the risk of heart attacks and strokes."4.81Potential cardioprotective actions of no-releasing aspirin. ( Fiorucci, S; Ignarro, LJ; Wallace, JL, 2002)
"The Hypertension Optimal Treatment (HOT) study was designed to answer two questions: whether low-dose aspirin (75 mg/day) is effective in the primary prevention of myocardial infarction, without an increase in cerebral haemorrhage in hypertensive patients whose blood pressure is well controlled, and whether there are additional benefits with a progressive reduction of diastolic blood pressure from 90 mmHg to below 80 mmHg."4.80Hypertension optimal treatment (HOT) study: a brilliant concept, but a qualified success. ( Chalmers, J, 1998)
" Secondary prevention strategies include smoking cessation; the control of hyperlipidemia, obesity and diabetes; the management of hypertension and stress; exercise; the use of drugs such as beta blockers and aspirin, and increased attention to general health."4.77Secondary prevention in elderly survivors of heart attacks. ( Davenport, J; Whittaker, K, 1988)
"Results from previous studies indicate that use of aspirin may improve colorectal cancer (CRC) survival."4.31Low-dose aspirin use and colorectal cancer survival in 32,195 patients-A national cohort study. ( Ekström Smedby, K; Glimelius, B; Martling, A; Matthiessen, P; Nordenvall, C; Shahrivar, M; Syk, I; Weibull, CE, 2023)
"There were no significant differences in age, sex, alcohol consumption, smoking habits, history of diabetes, hypertension, and dyslipidemia, and aspirin intake between the eradication and non-eradication groups (3783 vs."4.31Preventive effect of Helicobacter pylori eradication on the coronary heart diseases depending on age and sex with a median follow-up of 51 months. ( Ahn, S; Choi, Y; Hwang, IC; Kim, N; Kim, SB; Lee, DH; Lim, SH; Park, J; Park, YS; Shin, CM; Song, DH; Yoon, H, 2023)
"Long-term use of aspirin and severity of cerebral infarction are risk factors for gastrointestinal bleeding in cerebral infarction patients receiving dual antiplatelet therapy."4.31Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy. ( Huang, J; Liao, F; Shu, X; Tang, J, 2023)
"To investigate the association between low-dose aspirin use for primary prevention and self-reported kidney stones prevalence in the 40-79 years old population."4.31Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study. ( Chen, Y; Huang, F; Li, Y; Yang, M, 2023)
"Hematoma growth (HG) affects the prognosis of patients with spontaneous intracranial hematoma (ICH), but there is still a lack of evidence about the effects of aspirin (acetylsalicylic acid, ASA) on HG in patients with severe ICH."4.12Aspirin does not affect hematoma growth in severe spontaneous intracranial hematoma. ( Cao, Y; Guo, R; Jiang, P; Liu, Q; Liu, Y; Mo, S; Wang, K; Wang, S; Wu, J; Yang, J; Yang, S; Yang, Y; Zhang, J, 2022)
"Despite the overall association of aspirin on reduced hepatocellular carcinoma (HCC) risk, there have been few studies on its benefit according to specific clinical conditions among hepatitis B virus (HBV)-infected patients."4.12Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study. ( Ahn, SH; Kim, BK; Yoon, JH; Yun, B, 2022)
"Aspirin use for primary prevention was higher in patients with hypertension compared to patients without hypertension [328 (21."4.12An Evaluation of Aspirin Treatment Preferences ORIGINAL INVESTIGATION of Physicians in Hypertensive Patients in Terms of Current Guidelines: A Subgroup Analysis of the ASSOS Trial in Turkey. ( Altuntaş, E; Aslan, O; Asoğlu, R; Başaran, Ö; Biteker, M; Çelik, O; Çelik, Y; Çil, C; Civan, M; Demirci, E; Doğan, T; Kalkan, S; Karaarslan, O; Küçük, E; Küçüksu, Z; Memiç Sancar, K; Taylan, G; Yetim, M, 2022)
"To evaluate the accuracy of the EDAN SA-10 oscillometric upper-arm professional office ambulatory blood pressure (BP) monitor in general population according to the Association for the Advancement of Medical Instrumentation (AAMI)/European Society of Hypertension (ESH)/International Organization for Standardization (ISO) Universal Standard (ISO 81060-2:2018)."4.12Validation of the EDAN SA-10 ambulatory blood pressure monitor in general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Universal Stan ( Li, L; Liu, K; Ren, J; Wang, B; Yin, S, 2022)
" Univariate analysis showed that a family history of CHD, history of type 2 diabetes, hypertension, smoking, and drinking, discontinuation of aspirin, use of conventional dose statins, calcified lesions, ≥ 3 implanted stents, stent length ≥ 30 mm, stent diameter < 3 mm, and tandem stent increased the risk of restenosis."4.12Risk factors for in-stent restenosis after coronary stent implantation in patients with coronary artery disease: A retrospective observational study. ( Bian, YJ; Liu, Y; Xue, YT; Zhang, J; Zhang, Q; Zhao, K, 2022)
"Decision tree analysis was created using R software to evaluate four approaches to aspirin prophylaxis in the United States: no aspirin, United States Preventive Service Task Force (USPSTF) with Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) hypertension guidelines, USPSTF with ACC/AHA hypertension guidelines, as well as universal aspirin prophylaxis."4.02The Impact of the New Hypertension Guidelines to Low-Dose Aspirin Prophylaxis Eligibility for the Prevention of Preeclampsia: A Cost-Benefit Analysis. ( Balasooriya, MM; Boscia, AL; Dalkiran, E; Putra, M; Sokol, RJ, 2021)
"Acetylsalicylic acid (aspirin) is commonly used for primary and secondary prevention of cardiovascular diseases."4.02The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection. ( Avramovich, E; Frenkel-Morgenstern, M; Golan-Cohen, A; Gorohovski, A; Green, I; Magen, E; Merzon, E; Vinker, S, 2021)
"Aspirin reduced the risks of MACCE and cancer without increasing the bleeding risk in elderly Koreans with hypertension, T2DM, or dyslipidemia."3.96Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea. ( Jung, M; Lee, S, 2020)
"(1) To evaluate the rates of implementation of the 2016 American College of Obstetricians and Gynecologists guideline over time; and (2) to evaluate the effectiveness of aspirin for the prevention of superimposed preeclampsia and other adverse maternal and neonatal outcomes in women with chronic hypertension before and after this guideline."3.96Impact of the ACOG guideline regarding low-dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension. ( Banala, C; Berghella, V; Boelig, RC; Cruz, Y; Moreno, S; Roman, A; Saccone, G; Schoen, CN, 2020)
"This study aimed to investigate the effectiveness of monotherapy acetylsalicylic acid (ASA) and warfarin for stroke prevention in low-risk atrial fibrillation (AF) by using a population- -based cohort study in Taiwan."3.91Monotherapy of acetylsalicylic acid or warfarin for prevention of ischemic stroke in low-risk atrial fibrillation: A Easter Asian population-based study. ( Chen, HC; Liu, CY, 2019)
"Despite its well-known antithrombotic properties, the effect of aspirin on blood pressure (BP) and hypertension pathology is unclear."3.91Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat. ( Andrews, KL; Chin-Dusting, JPF; Dragoljevic, D; Gaspari, T; Jefferis, AM; Jennings, GL; Khan, SI; Lee, MKS; Moore, XL; Murphy, AJ; Shihata, WA; Vinh, A, 2019)
"To examine whether maternal aspirin use during pregnancy is associated with childhood blood pressure."3.91Association of intrauterine exposure to aspirin and blood pressure at 7 years of age: a secondary analysis. ( Chen, Y; Wang, B; Zhang, J; Zhang, Y; Zhao, D; Zhu, J, 2019)
"We examined whether the efficacy of low-dose acetylsalicylic acid (aspirin) for primary prevention of cardiovascular events is influenced by blood pressure (BP) using data from patients aged 60-85 years with hypertension, dyslipidemia, and/or diabetes, but without cardiovascular disease of the Japanese Primary Prevention Project."3.91Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks. ( Ando, K; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Uemura, Y; Yamazaki, T; Yokoyama, K, 2019)
"Calcium and low-dose aspirin are two potential approaches for primary prevention of hypertensive disorders of pregnancy (HDP)."3.91Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study. ( Bekker, MN; Browne, JL; Crombag, NMT; Franx, A; Grobbee, DE; van der Graaf, R; Vestering, A, 2019)
" Ibrutinib use, age, hypertension, and previous use of ACE inhibitors, angiotensin receptor blocker use, β blocker use, and aspirin use were independently associated with incident arrhythmias."3.91Rates and Risk of Atrial Arrhythmias in Patients Treated With Ibrutinib Compared With Cytotoxic Chemotherapy. ( Armanious, M; Chavez, JC; Emole, J; Fradley, MG; Gliksman, M; Lee, DH; McLeod, H; Pinilla-Ibarz, J; Rhea, I; Schabath, MB; Shah, B; Viganego, F; Walko, C; Welter-Frost, A, 2019)
" Recommendations address diagnosis and treatment of cardiovascular risk factors (hypertension and dyslipidemia), aspirin use, screening for and treatment of coronary heart disease, and lifestyle interventions."3.88Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018. ( Chamberlain, JJ; Johnson, EL; Leal, S; Peterson, L; Rhinehart, AS; Shubrook, JH, 2018)
"We used a single, integrated, microsimulation model to generate comparable results for 3 services recommended by the US Preventive Services Task Force: aspirin counseling for the primary prevention of CVD and colorectal cancer, screening and treatment for lipid disorders (usually high cholesterol), and screening and treatment for hypertension."3.85Health Benefits and Cost-Effectiveness of Asymptomatic Screening for Hypertension and High Cholesterol and Aspirin Counseling for Primary Prevention. ( Dehmer, SP; Flottemesch, TJ; LaFrance, AB; Maciosek, MV, 2017)
"The beneficial effect of aspirin in the prevention of preterm preeclampsia may not apply in pregnancies with chronic hypertension."3.85Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history. ( Akolekar, R; De Stefani, L; Delgado, JL; Evangelinakis, N; Gonzalez-Vanegas, O; Jani, JC; Leipold, G; Nicolaides, KH; Persico, N; Plasencia, W; Poon, LC; Rolnik, DL; Shearing, S; Syngelaki, A; Tsokaki, T; Wright, D, 2017)
" Risk factors for pregnancy complications, including premature delivery before 34 gestational weeks, hypertensive disorders of pregnancy, thrombocytopenia, and light-for-date neonate, were evaluated in 51 women who received low dose aspirin (LDA) plus unfractionated heparin (UFH) and delivered after 24 GW."3.85Factors associated with adverse pregnancy outcomes in women with antiphospholipid syndrome: A multicenter study. ( Deguchi, M; Fujita, D; Makino, S; Miki, A; Morikawa, M; Murashima, A; Sugiura-Ogasawara, M; Yamada, H, 2017)
" In a cross-sectional study of 787 patients with newly diagnosed clinical stage IB or II melanoma, we estimated odds ratios for the association of proinflammatory factors (high body mass index, diabetes, cardiovascular disease, hypertension, and smoking) or the use of anti-inflammatory medications (statins, aspirin, corticosteroids, and nonsteroidal anti-inflammatory drugs), with ulcerated primary melanoma using regression models and subgroup analyses to control for melanoma thickness and mitotic rate."3.85Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma. ( Green, AC; Hughes, MCB; Khosrotehrani, K; Malt, M; Smith, D; Smithers, BM; van der Pols, JC; von Schuckmann, LA, 2017)
"The effect of prior use of aspirin (ASA) on the onset of acute coronary syndrome (ACS) has not been clarified."3.85Association Between Prior Aspirin Use and Morphological Features of Culprit Lesions at First Presentation of Acute Coronary Syndrome Assessed by Optical Coherence Tomography. ( Araki, M; Hada, M; Hamaya, R; Hoshino, M; Ichijo, S; Kakuta, T; Kanaji, Y; Kanno, Y; Lee, T; Matsuda, J; Murai, T; Niida, T; Usui, E; Yonetsu, T, 2017)
"The aim of this study was to investigate whether aspirin use can reduce the incidence of gastric cancer in patients with hypertension or type 2 diabetes."3.83Long-Term Low-Dose Aspirin Use Reduces Gastric Cancer Incidence: A Nationwide Cohort Study. ( Choi, IJ; Kim, JH; Kim, SY; Kim, YI; Kim, YW; Lee, JH; Park, JH; Ryu, KW, 2016)
"Aspirin use for primary prevention in patients at high risk with diabetes mellitus (DM) is often recommended under the assumption that most patients with DM have coronary artery disease (CAD)."3.83Value of Coronary Computed Tomography Angiography in Tailoring Aspirin Therapy for Primary Prevention of Atherosclerotic Events in Patients at High Risk With Diabetes Mellitus. ( Bax, JJ; de Graaf, MA; Delgado, V; Dimitriu-Leen, AC; Jukema, JW; Kharagjitsingh, AV; Knuuti, J; Kroft, LJ; Scholte, AJ; van den Hoogen, IJ; van Rosendael, AR; Wolterbeek, R, 2016)
" Concentration of sTWEAK in HF-REF was affected by white blood cell count and aspirin intake, while sCD163 by exercise capacity, LV diastolic volume, CRP and presence of arterial hypertension."3.83Alterations of soluble TWEAK and CD163 concentrations in patients with chronic heart failure. ( Galar, B; Jakim, P; Jasiewicz, M; Kaminski, KA; Lisowska, A; Marcinkiewicz-Siemion, M; Miklasz, P; Musial, WJ; Ptaszynska-Kopczynska, K; Waszkiewicz, E; Witkowski, M, 2016)
"To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia."3.83Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016)
"Low-dose aspirin has been hypothesized as being a potential host modulatory agent for periodontitis treatment."3.81Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012. ( Demmer, RT; Ioannou, AL; Kotsakis, GA; Michalowicz, BS; Thai, A, 2015)
" This study aims to investigate whether calcium channel blockers plus low dosage aspirin therapy can reduce the incidence of complications during pregnancy with chronic hypertension and improve the prognosis of neonates."3.81The effect of calcium channel blockers on prevention of preeclampsia in pregnant women with chronic hypertension. ( Jiang, N; Liu, L; Liu, Q; Yang, WW; Zeng, Y, 2015)
" Case-control analysis showed that comorbidities of hypertension, purpura and thrombocytopenia, and the use of aspirin were significantly associated with the risk of NTSCH."3.81Incidence of Non-Traumatic Subconjunctival Hemorrhage in a Nationwide Study in Taiwan from 2000 to 2011. ( Chao, SC; Hu, DN; Jonas, JB; Kuan, PT; Lin, CY; Mou, CH; Nien, CW; Sung, FC, 2015)
"The US Preventive Services Task Force recommends aspirin use for men aged 45 to 79, when the potential benefit of preventing myocardial infarctions outweighs the potential harm of gastrointestinal hemorrhage."3.81Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013. ( Fleming, E; Perry, GS; Tchwenko, S, 2015)
"Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors."3.80Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid. ( Beckmann, Y; Ciftçi, Y; Seçil, Y; Tokuçoğlu, F, 2014)
" This adherence was concerned particularly with co-medication in patients diagnosed with hypertension, aspirin prescription in elderly patients and the achievement of target lipid levels following the prescription of statins."3.79Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study. ( Hintersteiner, J; Johnson, J; Kamyar, MR; Kautzky, A; Kautzky-Willer, A; Lemmens-Gruber, R; Saukel, J; Stich, K, 2013)
" Additional subgroup analysis included the presence of hypertension, diabetes, low-density lipoprotein levels, sex, and use of aspirin."3.79Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study. ( El-Charabaty, E; El-Sayegh, S; Saifan, C, 2013)
"The widespread use of aspirin-driven vascular prevention strategies does not impede the occurrence of first and recurrent ischemic strokes in numerous subjects."3.78Ischemic stroke in patients receiving aspirin. ( Ameriso, S; Ameriso, SF; Povedano, GP; Pujol Lereis, VA, 2012)
"Only 50% of patients who would benefit from warfarin therapy for atrial fibrillation (AF) receive treatment because of clinical concerns regarding chronic anti-coagulation."3.78Role for the left atrial appendage occlusion device in managing thromboembolic risk in atrial fibrillation. ( Alison, JF; Lockwood, S; Mottram, P; Obeyesekere, MN, 2012)
" Old age, bilateral diverticulosis, presence of atherosclerosis related diseases (hypertension, diabetes mellitus, ischemic heart disease, obesity), use of aspirin, NSAIDs and calcium channel blocker, increased the risk of bleeding."3.78[The risk factors for colonic diverticular bleeding]. ( Hwang, JH; Jeong, SH; Jo, HJ; Jung, HC; Kim, HY; Kim, JW; Kim, N; Lee, DH; Lee, SH; Park, H; Park, YS; Seo, PJ; Shin, CM; Song, IS; Suh, S, 2012)
"In this retrospective observational study including women with pre-existing hypertension, pre-gestational diabetes or previous placental-mediated complications, we compared the rates of pre-eclampsia, early-onset and severe pre-eclampsia between women who used 81 mg of aspirin (ASA) throughout pregnancy without platelet function analyser (PFA-100®) monitoring ("group ASA no PFA") and those in whom the aspirin dosage was adjusted according to PFA-100® results ("group ASA and PFA")."3.77Is testing for aspirin response worthwhile in high-risk pregnancy? ( Rey, E; Rivard, GE, 2011)
"Cyclo-oxygenase-1 and cyclo-oxygenase-2 deficient mice and their cultured aortic smooth muscle cells were used to investigate the role of these enzymes in angiotensin II induced superoxide production and hypertension."3.77Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension. ( De Champlain, J; Duchemin, S; Girouard, H; Laplante, MA; Wu, R, 2011)
"The regular use of aspirin and non-aspirin analgesics were both associated with an increased risk of developing hypertension, independently of other risk factors."3.76Aspirin, non-aspirin analgesics and the risk of hypertension in the SUN cohort. ( Alonso, A; Bes-Rastrollo, M; Beunza, JJ; Martínez-González, MA; Núñez-Córdoba, JM; Toledo, E, 2010)
"This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive stroke-prone rats (SHRSP)."3.76Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin. ( Ballerio, R; Banfi, C; Blanc-Guillemaud, V; Brioschi, M; Castiglioni, L; Gelosa, P; Gianella, A; Guerrini, U; Lerond, L; Nobili, E; Pignieri, A; Sironi, L; Tremoli, E, 2010)
" The quality of control of diabetes, hypertension or hyperlipidemia and the use of aspirin were assessed in 2914 patients at baseline and after 3,7 years."3.75["Diabetes in Germany"(DIG) study. A prospective 4-year-follow-up study on the quality of treatment for type 2 diabetes in daily practice]. ( Benke, I; Hanefeld, M; Köhler, C; Ott, P; Stelzer, J, 2009)
"Compared with other non-steroid anti-inflammatory drugs (NSAIDs), aspirin is not correlated to hypertension."3.75Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation. ( Giachini, FR; Tostes, RC; Webb, RC; Ying, Z, 2009)
"A considerable proportion of patients discontinue dipyridamole therapy because of headache."3.75Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin. ( Algra, A; Halkes, PH; Kappelle, LJ; Koudstaal, PJ; van Gijn, J, 2009)
"We report a case of myocardial infarction associated with the use of sumatriptan and review the literature regarding similar cases."3.75Acute myocardial infarction with sumatriptan: a case report and review of the literature. ( Chalaupka, FD, 2009)
"To quantify the relative risk of epistaxis for patients taking low-dose aspirin or clopidogrel compared to patients taking neither drug."3.75Clopidogrel versus low-dose aspirin as risk factors for epistaxis. ( Molony, NC; Rainsbury, JW, 2009)
"We report a 56-year-old patient who had been taking antihypertensive medication in combination with prophylactic aspirin for 19 years who was diagnosed with stable angina with significant coronary artery stenosis on angiography."3.75Spontaneous spinal epidural hematoma: an urgent complication of adding clopidogrel to aspirin therapy. ( Chung, HS; Kim, JH; Kwon, TH; Moon, HJ; Park, YK, 2009)
" The Task Force has: 1) dropped the age for routine screening for Chlamydia in sexually active women from 25 years and younger to 24 and younger; 2) added a recommendation against the use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent colorectal cancer (CRC); 3) changed its recommendation on screening for carotid artery stenosis."3.74Should you screen--or not? The latest recommendations. ( Campos-Outcalt, D, 2008)
" Ischemic stroke was predicted by hypertension, myocardial infarction, low-dose aspirin, comorbidity score, Health Assessment Questionnaire score, and presence of total joint replacement, but not by diabetes, smoking, exercise, or body mass index."3.74Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: a nested, case-control study. ( Hallenbeck, JM; Michaud, K; Nadareishvili, Z; Wolfe, F, 2008)
"05) of stroke with hypertension and diabetes mellitus; of myocardial infarction with hypertension, hypercholesterolemia, obesity, and smoking; and of peptic ulcer disease with aspirin, NSAIDs, and potassium."3.74Validation studies of the health improvement network (THIN) database for pharmacoepidemiology research. ( Bilker, WB; Lewis, JD; Schinnar, R; Strom, BL; Wang, X, 2007)
" hypertension, aspirin use) with emergency department admission due to epistaxis."3.74Research for bleeding tendency in patients presenting with significant epistaxis. ( Buyukasik, Y; Coşkun, F; Dizdar, O; Kalyoncu, U; Karadag, O; Karakiliç, E; Onal, IK; Ozakin, E, 2007)
"Aspirin prevented and partially reversed ACTH-induced hypertension in the SD rats."3.74Aspirin prevents and partially reverses adrenocorticotropic hormone-induced hypertension in the rat. ( Miao, Y; Whitworth, JA; Zhang, Y, 2007)
" Hypertension, diabetes mellitus, transient ischemic attack (TIA), hyperlipemia and mural thrombus in left atrium were significantly correlated with the recurrence rate by univariate Cox proportional hazards regression analysis; but aspirin therapy, warfarin therapy and hypertension control were protective factors for the recurrence of ischemic stroke in patients with NVAF."3.74[A study on the recurrence of ischemic stroke in nonvalvular atrial fibrillation]. ( Cai, YY; Hu, Y; Luo, M; Quan, HB; Xie, RM, 2007)
"The aim of this study was to evaluate the relationship of obesity, leptin, insulin resistance and C-reactive protein (CRP) with coronary heart disease (CHD) risk factors in patients with Type 2 diabetes mellitus (DM) with CHD compared with those with Type 2 DM without CHD."3.73Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance. ( Abdella, NA; Al Jebely, S; Al Mohammedi, H; Al Ozairi, ES; Mojiminiyi, OA; Moussa, MA; Zaki, M, 2005)
"A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB."3.73Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease. ( Chen, WH; Cheng, X; Lai, KC; Lam, KF; Lau, CP; Lee, PY; Li, SW; Ng, M; Ng, W; Tse, HF; Wong, WM, 2006)
"Although aspirin is useful in reducing platelet activation and cardiovascular events, its effects on platelet levels of angiogenic factors, such as vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang-1), and markers of platelet activation in hypertension are unknown."3.73Effects of aspirin on intra-platelet vascular endothelial growth factor, angiopoietin-1, and p-selectin levels in hypertensive patients. ( Blann, AD; Lip, GY; Nadar, S, 2006)
"Using automatic erythrocyte aggregometer type MA-1 (Myrenne gmbh, Germany), we investigated the hypothesis that therapeutic effectiveness of quinapril--angiotensin converting enzyme inhibitor (ACEI)--in the treatment of hypertension would correlate with improvement of red blood cell (RBC) aggregability."3.72Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension. ( Adamek-Guzik, T; Korbut, R; Korbut, RA; Madej, J, 2003)
"Chronic in vivo treatment with aspirin prevented the development of hypertension and reduced insulin resistance significantly in chronically glucose-fed rats."3.71Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. ( de Champlain, J; El Midaoui, A; Wu, R, 2002)
"Use of NSAIDs and use of acetaminophen were significantly associated with increased risk of hypertension, but aspirin use was not."3.71Frequency of analgesic use and risk of hypertension in younger women. ( Curhan, GC; Rosner, B; Stampfer, MJ; Willett, WC, 2002)
"Analysis of results of randomized controlled studies revealed pronounced attenuation of vasodilating, natriuretic, and cardioprotective effects of angiotensin converting enzyme inhibitors (ACEI) by concomitant use with of indomethacin and aspirin in patients with hypertension, chronic heart failure, and acute myocardial infarction."3.71[Interaction of angiotensin converting enzyme inhibitors with nonsteroidal antiinflammatory drugs]. ( Batyraliev, TA; Malysheva, NV; Preobrazhenskiĭ, DV; Sidorenko, BA; Tsurko, VV, 2002)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."3.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
" If thrombophilia was diagnosed on the basis of hyperhomocysteinemia, the treatment consisted of aspirin, pyridoxine and folic acid, instead."3.71Non-pregnant circulatory volume status predicts subsequent pregnancy outcome in normotensive thrombophilic formerly preeclamptic women. ( Aardenburg, R; de Leeuw, PW; Ekhart, TH; Peeters, LL; Spaanderman, ME; van der Heijden, OW; van Eyck, J; van Eyndhoven, HW, 2001)
"As platelet hyperactivity is important in atherosclerosis and smoking, we hypothesized higher levels of soluble platelet membrane glycoprotein V (gpV) in 95 patients with peripheral artery disease (PAD) and 92 with coronary artery disease (CAD) compared to 99 healthy controls, and examined the effects of aspirin and of smoking two cigarettes on soluble gpV and platelet function."3.71Increased platelet glycoprotein V levels in patients with coronary and peripheral atherosclerosis--the influence of aspirin and cigarette smoking. ( Blann, AD; Cazenave, JP; Galajda, P; Gurney, D; Lanza, F; Lip, GY; Moog, S, 2001)
"It has been reported that administration of low-dose aspirin significantly reduces the frequency of major cardiovascular events in patients with hypertension and coronary artery disease."3.71Effects of low-dose aspirin on endothelial function in hypertensive patients. ( Monobe, H; Nakamura, K; Ohe, T; Yamanari, H, 2001)
" ASA treatment also completely inhibited the angiotensin II-induced hypertension and O(2)(-) production."3.71Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats. ( de Champlain, J; Lamontagne, D; Wu, R, 2002)
"These findings suggest that a number of ACE-inhibited patients are susceptible to 300 mg/day aspirin, regardless of hypertension severity."3.70Antihypertensive efficacy of angiotensin converting enzyme inhibition and aspirin counteraction. ( Alimento, M; Campodonico, J; Celeste, F; Guazzi, M; Guazzi, MD; Rossi, M; Santambrogio, G; Trabattoni, D, 1998)
", age; left ventricular function; left main coronary artery disease; urgent priority; gender; previous cardiac surgery; concurrent cardiovascular surgery; chronic lung disease; creatinine concentration; hemoglobin concentration; diabetes; hypertension; cerebrovascular disease; recent myocardial infarction; prior vascular surgery; number of arteries bypassed; and regular daily treatment with beta-blockers, aspirin within 5 days, calcium antagonists, angiotensin converting enzyme (ACE) inhibitors, digoxin, or warfarin."3.70Drug therapy before coronary artery surgery: nitrates are independent predictors of mortality and beta-adrenergic blockers predict survival. ( Gibbs, NM; Mahon, BD; Newman, MA; Sheminant, MR; Weightman, WM; Whitford, EG, 1999)
" Time trends were analysed for the use of aspirin, management of hypertension and atrial fibrillation prior to the presenting episode."3.70Secular trends in the management of hypertension and atrial fibrillation in patients presenting with stroke. ( Kalra, L; Perez, I; Smithard, DG, 2000)
"To assess the relationship of aspirin use and ischemic cranial nerve palsies among patients with diabetes mellitus and hypertension."3.70Aspirin use and the prevention of acute ischemic cranial nerve palsy. ( Cipollo, CL; Johnson, LN; Krohel, GB; Madsen, RW; Stetson, SW, 2000)
"Elderly men are more likely than elderly women to receive aspirin and ticlopidine and equally like to receive warfarin after a stroke."3.70Sex differences and similarities in the management and outcome of stroke patients. ( Austin, PC; Holroyd-Leduc, JM; Kapral, MK; Tu, JV, 2000)
"The Hypertension Optimal Treatment study was a large, randomized, multicenter study to determine the answers to two questions: 1) what is the optimal target blood pressure to be sought in the treatment of patients with moderate hypertension? and 2) does low dose aspirin therapy decrease morbidity and mortality in patients with hypertension? After 3."3.70The Hypertension Optimal Treatment Study: what did it give us? ( Bryg, RJ; Graettinger, WF, 1999)
"(1) Aspirin reduces the risk of myocardial infarction in men over 40 with no history of cardiovascular disease, and in hypertensive patients of both sexes over that age."3.70Antiplatelet drugs in cardiovascular prevention: coronary events and stroke: primary prevention. ( , 2000)
"To study platelet aggregation (PA) in patients with left ventricular hypertrophy (LVH) in essential hypertension (EH) and hypertrophic cardiomyopathy (HTCM), and to assess aspirin treatment effects."3.70[Platelet aggregation in patients with various forms of left ventricular hypertrophy and its changes at long-term follow-up and treatment]. ( Gabbasov, ZA; Iurenev, AP; Riazanov, AS, 2000)
"To determine whether the administration of acetylsalicylic acid (ASA, also known as Aspirin) differentiates patients with renovascular hypertension from those with essential hypertension, in order to provide a simple alternative to more expensive forms of diagnosis for this condition."3.69Acetylsalicylic acid (aspirin) test for the diagnosis of renovascular hypertension. ( Gluszek, J; Gracz, M; Kara-Perz, H; Posadzy-Malaczynska, A; Pupek-Musialik, D; Tykarski, A, 1997)
"To describe patterns of prescription in the Netherlands of low-dose aspirin in pregnancy."3.68Low-dose aspirin in pregnancy: changes in patterns of prescription in The Netherlands. ( Bremer, HA; Wallenburg, HC, 1993)
"Low dose Aspirin in pregnancy reduces the incidence of intra uterine growth retardation (IUGR) and pregnancy induced hypertension (PIH) in women at risk for these complications."3.68Low dose aspirin in pregnancy: a clinical and biochemical study of effects on the newborn. ( Foschini, M; Frusca, T; Soregaroli, M; Tarantini, M; Valcamonico, A, 1993)
"Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT)."3.68Aspirin test for differentiation of unilateral renovascular hypertension from hyperreninemic essential hypertension. ( Akabane, S; Imanishi, M; Ito, K; Kawamura, M; Kimura, K; Kojima, S; Kuramochi, M; Matsushima, Y; Ohta, M; Takamiya, M, 1991)
"Urinary excretion of thromboxane B2 metabolites as markers of thromboxane A2 synthesis was measured in eight patients with moderate to severe pregnancy-induced hypertension and in six normotensive pregnant women at term."3.68Thromboxane A2 synthesis in pregnancy-induced hypertension. ( Fitzgerald, DJ; FitzGerald, GA; Mayo, G; Murray, R; Rocki, W, 1990)
"Regular use of analgesic drugs containing phenacetin is associated with an increased risk of hypertension and mortality and morbidity due to cardiovascular disease, as well as an increased risk of mortality due to cancer and urologic or renal disease."3.68An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987) ( Dubach, UC; Rosner, B; Stürmer, T, 1991)
"Low-dose Aspirin inhibits thromboxane A2 with minimal effects on prostacyclin and induces clinical improvements in pre-eclampsia."3.68Treatment of severe pre-eclampsia by acetyl salicylic acid. ( Abd-Rabbo, S; Khowessah, M; Shaala, S; Toppozada, M; Zoheir, A, 1991)
" In five cases, temporary reversal of the HELLP syndrome was achieved using low-dose aspirin and corticosteroids."3.68Prolongation of premature gestation in women with hemolysis, elevated liver enzymes and low platelets. A report of five cases. ( Burke, MS; Heyborne, KD; Porreco, RP, 1990)
"Increased platelet aggregation induced by ADP and arachidonic acid was observed in 12 patients with essential hypertension compared with 12 control subjects, but not after pretreatment with acetylsalicylic acid."3.67Increased platelet aggregation and intracellular calcium in hypertensive patients: effects of cyclo-oxygenase blockade. ( Arosio, E; Guzzo, P; Lechi, A; Lechi, C; Minuz, P; Paluani, F; Sinigaglia, D, 1989)
"Results of recent clinical trials on secondary prevention of ischemic heart disease indicate that judicious, long-term administration of adrenergic beta blockers and platelet-active drugs such as aspirin and Persantine (dipyridamole) would seem to yield protection against mortality associated with acute myocardial infarction, including sudden death."3.67Clinical trials on the efficacy of pharmacologic intervention reducing mortality from cardiovascular diseases. ( Borhani, NO, 1985)
"Decreased incidence of proteinuric hypertension after low-dose aspirin therapy is hypothesized to be a consequence of selective thromboxane A2 inhibition and sparing of prostacyclin."3.67Low-dose aspirin. I. Effect on angiotensin II pressor responses and blood prostaglandin concentrations in pregnant women sensitive to angiotensin II. ( Brown, CE; Cox, SM; Gant, NF; Magness, RR; Rosenfeld, CR; Spitz, B, 1988)
"A mode of interaction of bradykinin with prostaglandins (PGs) in pain were compared with that in acute inflammation."3.67Different modes of interaction of bradykinin with prostaglandins in pain and acute inflammation. ( Harada, Y; Hori, Y; Katori, M; Tanaka, K; Uchida, Y, 1986)
" Seven recently completed clinical trials, the Coronary Drug Project, the Aspirin Myocardial Infarction Study, the Anturane Reinfarction Trial, the Hypertension Detection and Follow-Up Program and three drug trials of betablockers, are reviewed from the perspective of both their clinical and methodological significance."3.66Overview of recent clinical and methodological advances from clinical trials of cardiovascular disease. ( Friedewald, WT; Schoenberger, JA, 1982)
"Verapamil, a known Ca++ antagonist, has vasodilator properties and is of use in the management of mild to moderate hypertension."3.66Modification of anti-hypertensive action of verapamil by inhibition of endogenous prostaglandin synthesis. ( Das, UN, 1982)
"The aggregability of platelets to arachidonic acid (AA) was investigated in 26 control subjects, 40 patients with essential hypertension, 20 patients with ischemic cerebrovascular diseases (CVD) not taking aspirin and 11 patients with CVD taking aspirin."3.66Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease. ( Abe, H; Fujisawa, A; Kimura, K; Kusunoki, M; Matsumoto, M; Matsuyama, T; Uyama, O; Yoneda, S, 1981)
"The ability of platelets to synthesize thromboxane B2 (TxB2) from arachidonic acid (AA) or prostaglandin H2 (PGH2) was studied in 26 control subjects, 40 patients with essential hypertension, 20 patients with cerebrovascular disease (CVD) not taking aspirin and 11 patients with CVD taking aspirin."3.66Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. ( Imaizumi, M; Kayama, N; Matsumoto, M; Miyamoto, T; Nukada, T; Uyama, O; Yoneda, S, 1980)
"The proliferation of aortic smooth muscle cells (ASMC) of Wistar rats, impaired by risk factors such as arterial hypertension, diabetes mellitus, atherogenic diet and staphylolysin injections and of normal Wistar rats treated with antirheumatic drugs such as prednisolone and acetylsalicylic acid was investigated."3.66Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells. ( Hauss, WH; Mey, J; Schulte, H, 1979)
"The effects of prostaglandin E2 (PGE2) and a prostaglandin inhibitor, indomethacin, on the development of adrenal regeneration hypertension (ARH) were investigated."3.65Effects of prostaglandin E2 and prostaglandin inhibitors on adrenal regeneration hypertension. ( Eversole, WJ; Paulson, DJ, 1977)
"The results of two large independent studies involving a combined total of 776 patients treated in hospital with a discharge diagnosis of acute myocardial infarction and 13,898 patients with other discharge diagnoses showed a negative association between regular aspirin intake and non-fatal myocardial infarction."3.65Regular aspirin intake and acute myocardial infarction. ( , 1974)
"A proportion of patients with embolic stroke of undetermined source have silent atrial fibrillation (AF) or develop AF after the initial evaluation."3.01Predictors of Atrial Fibrillation Development in Patients With Embolic Stroke of Undetermined Source: An Analysis of the RE-SPECT ESUS Trial. ( Bahit, MC; Brainin, M; Brueckmann, M; Cronin, L; Diener, HC; Easton, JD; Granger, CB; Grauer, C; Kleine, E; Lopes, RD; Lyrer, P; Meyerhoff, J; Sacco, RL; Segura, T; Wachter, R, 2021)
"Preeclampsia is a hypertensive disorder of pregnancy affecting up to 8% of pregnancies."3.01Aspirin and Pravastatin for Preeclampsia Prevention in High-Risk Pregnancy. ( Costantine, MM; Eid, J; Rood, KM, 2023)
"Aspirin was not found to substantially diminish the risk of incidence of preeclampsia, but it did show some beneficial effects."3.01Role of aspirin in the prevention of preeclampsia in previously hypertensive pregnant women: A Meta-Analysis. ( Ashraf Jahangeer, SM; Khan, AA; Mansoor, M, 2023)
"Preeclampsia and gestational hypertension are common pregnancy complications associated with adverse maternal and child outcomes."3.01Polygenic prediction of preeclampsia and gestational hypertension. ( Antopia, MC; Bhatta, L; Brumpton, BM; Cho, SMJ; Do, R; Gray, KJ; Guerrero, RF; Gupta, RM; Haas, DM; Honigberg, MC; Khan, RR; Koyama, S; Laisk, T; Martin, HC; Nadkarni, GN; Natarajan, P; Patel, AP; Patil, S; Pe'er, I; Saxena, R; Schuermans, A; Selvaraj, MS; Trinder, M; Truong, B; Urbut, SM; van Heel, DA; Vellarikkal, SK; Verma, SS; Vy, HMT; Xiao, B; Yan, Q; Zöllner, S, 2023)
"Aspirin users were at significantly lower risk of all-cause mortality compared to nonusers (HR = 0."3.01Association between aspirin use and cardiovascular outcomes in ALLHAT participants with and without chronic kidney disease: A post hoc analysis. ( Bond, M; Conant, A; Desai, N; Rahman, M; Wilson, B, 2021)
" evening) dosing on the anti-aggregative effect of platelets in patients with CAD and arterial hypertension (AH)."2.90The effect of acetylsalicylic acid dosed at bedtime on the anti-aggregation effect in patients with coronary heart disease and arterial hypertension: A randomized, controlled trial. ( Krasińska, B; Krasiński, M; Krasiński, Z; Miciak-Lawicka, E; Paluszkiewicz, L; Rzymski, P; Tykarski, A, 2019)
"Aspirin treatment may have reduced CVEs within a high CVE risk elderly population subgroup."2.90Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70). ( Ando, K; Goto, Y; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Uemura, Y; Yamazaki, T; Yokoyama, K, 2019)
"Given the burden of preeclampsia, the identification of women at high risk in early pregnancy is essential to allow for preventive strategies and close monitoring."2.82Screening for preeclampsia in twin pregnancies. ( Francisco, C; Gamito, M; Reddy, M; Rolnik, DL, 2022)
"In addition, treating chronic hypertension neither reduces nor increases fetal or newborn death or morbidity, regardless of the gestational age at which the antihypertensive treatment is started."2.82Toward personalized management of chronic hypertension in pregnancy. ( Kametas, N; Khalil, A; Magee, LA; von Dadelszen, P, 2022)
"Most retinal or subretinal hemorrhages in eyes enrolled in CATT were less than 1 DA."2.82Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials. ( Ahmed, O; Daniel, E; Grunwald, JE; Maguire, MG; Martin, DF; Ying, GS, 2016)
"When superimposed preeclampsia was present, it developed at an earlier gestational age among the group without GDM (35 ± 5 vs."2.82Rate of Gestational Diabetes Mellitus and Pregnancy Outcomes in Patients with Chronic Hypertension. ( Blackwell, SC; Haidar, ZA; Leon, MG; Longo, M; Mendez-Figueroa, H; Moussa, HN; Pedroza, C; Sibai, BM, 2016)
"The rate of superimposed preeclampsia was 28."2.79Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial. ( Atallah, AN; Kulay, L; Santos, GM; Sass, N; Souza, EV; Torloni, MR, 2014)
" An additional aim is to assess the effect of the polypill on LDL-c and BP compared to the administration of separate pills of identically dosed components of the polypill."2.79The evening versus morning polypill utilization study: the TEMPUS rationale and design. ( Bots, ML; Grobbee, DE; Lafeber, M; Rodgers, A; Spiering, W; Thom, S; Visseren, FL; Webster, R, 2014)
"The rate of postoperative hemorrhage, average postoperative hemorrhage volume, and mortality rate were significantly higher in the ASA-sensitive patients who received ASA therapy compared with patients who did not receive ASA therapy (all p < 0."2.78Effect of acetylsalicylic acid usage and platelet transfusion on postoperative hemorrhage and activities of daily living in patients with acute intracerebral hemorrhage. ( Chen, J; Li, G; Li, X; Li, Y; Mao, J; Sun, Z; Xiang, Y; Yang, X; Ye, Y; Zhang, J; Zhang, M; Zhang, W; Zhao, J; Zhao, W, 2013)
"Aspirin, which has both anti-inflammatory and anti-thrombotic effects, has the potential to influence CRP release."2.76The effect of aspirin on C-reactive protein in hypertensive patients. ( Chung, WY; Kim, CJ; Kim, MA; Kim, SH; Rho, EY; Seo, JB; Shin, S; Yoon, JH; Zo, JH, 2011)
"We studied 130 men and 186 women with untreated mild hypertension, 44."2.75Sex differences in the administration-time-dependent effects of low-dose aspirin on ambulatory blood pressure in hypertensive subjects. ( Ayala, DE; Hermida, RC, 2010)
"Aspirin resistance was defined as an aspirin reaction unit ≥550."2.75Aspirin resistance in hypertensive patients. ( Caymaz, O; Ozben, B; Ozben, T; Tanrikulu, AM, 2010)
"Aspirin resistance was defined as having a closure time (CT) of <186 s with Col/Epi cartridges despite regular aspirin therapy."2.74Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease. ( Nisanci, Y; Oflaz, H; Pamukcu, B; Tirnaksiz, E, 2009)
"Hypertension is more commonly diagnosed in older patients with atrial fibrillation than in the general population."2.73A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial. ( Fletcher, K; Hobbs, FD; Hurley, V; Ireson, R; Lip, GY; Mant, J, 2007)
"Several studies have shown that treatment of coronary heart disease (CHD) does not meet the goals set in recommendations."2.73Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting. ( Kähönen, M; Kallio, J; Kööbi, T; Lehtimäki, T; Lehtinen, R; Michou, SM; Niemelä, K; Nieminen, T; Nikus, K; Turjanmaa, V; Viik, J, 2007)
"Development of preeclampsia can be decreased by prescribing low-dose aspirin to high-risk women."2.72Family History of Hypertension, Cardiovascular Disease, or Diabetes and Risk of Developing Preeclampsia: A Systematic Review. ( Kay, VR; Smith, GN; Wedel, N, 2021)
"We examined the prevalence and medical treatment of hypertension among 15,904 ACS patients randomized in the SYMPHONY and 2nd SYMPHONY trials."2.71Prevalence and management of hypertension in acute coronary syndrome patients varies by sex: observations from the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes (SYMPHONY) randomized clinical ( Armstrong, PW; Aylward, PE; Bhapkar, MV; Frazier, CG; Klein, WW; Kristinsson, A; McGuire, DK; Newby, LK; Sadowski, Z; Shah, SH; Weaver, WD, 2005)
"Essential hypertension is one of the most important risk factors for cardiovascular diseases."2.70[The effect of aspirin on rheological properties of erythrocytes in essential hypertension]. ( Adamek-Guzik, T; Korbut, RA, 2002)
" Four variants of the course treatment were used: 1) monotherapy with enalapril maleate (2 mg twice a day); 2) enalapril maleate (5 mg twice a day) in combination with NSAID; 3) monotherapy with lisinopril (10 mg once a day); 4) lisinopril (10 mg once a day in combination with NSAID."2.70[Antihypertensive effect of enalapril and lisinopril administered in combination with nonsteroid anti-inflammatory agents]. ( Brodskaia, SA; Ivanov, SN; Savenkov, MP, 2001)
"The reduction in the incidence of intrauterine growth retardation (2."2.70Low dose acetylsalicylic acid in prevention of pregnancy-induced hypertension and intrauterine growth retardation in women with bilateral uterine artery notches. ( Iso-Mustajärvi, M; Kujansuu, E; Mäenpää, J; Vainio, M, 2002)
"Both high blood pressure and low blood pressure were independent prognostic factors for poor outcome, relationships that appear to be mediated in part by increased rates of early recurrence and death resulting from presumed cerebral edema in patients with high blood pressure and increased coronary heart disease events in those with low blood pressure."2.70Blood pressure and clinical outcomes in the International Stroke Trial. ( Bath, PM; Leonardi-Bee, J; Phillips, SJ; Sandercock, PA, 2002)
" The cardinal questions to be answered were: (1) the relationship between three targeted diastolic pressures (< or = 90, < or = 85 and < or = 80 mm Hg, respectively) and cardiovascular morbidity and mortality rates among hypertensives; and (2) the effect of low dosage aspirin (75 mg daily) on morbidity and mortality rates, compared with a placebo."2.69[The Hypertension Optimal Treatment (HOT) study: results of 12-month therapy related to age]. ( Kolloch, RE; Rahn, KH, 1998)
"Whether low-dose aspirin prevents preeclampsia is unclear."2.69Low-dose aspirin to prevent preeclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, S; Hauth, J; Klebanoff, M; Landon, M; Lindheimer, MD; Meis, P; Miodovnik, M; Paul, R; Sibai, B; Thom, E; Thurnau, G; VanDorsten, P, 1998)
"Eptifibatide was not associated with an increase in intracranial hemorrhage, and no significant effect on nonhemorrhagic stroke was observed."2.69Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. ( Alberts, MJ; Berdan, LG; Califf, RM; Deckers, J; Graffagnino, C; Granger, CB; Harrington, RA; Laskowitz, DT; Lincoff, AM; MacAulay, CM; Mahaffey, KW; Miller, JM; Simoons, ML; Sloan, MA; Topol, EJ, 1999)
"In addition, 6 transient ischemic attacks and 3 myocardial infarctions could be directly linked to CEA, for a total CEA event rate of 2."2.68An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. ACAS Investigators. Asymptomatic Carotid Atherosclerosis Study. ( Broderick, JP; Cohen, SN; Dempsey, RJ; Ernst, CB; Hosking, JD; Moore, WS; Robertson, JT; Toole, JF; Young, B, 1996)
"Hypertension is associated with an increased risk of myocardial infarction, and borderline isolated systolic hypertension predicts a possible but more modest increase in risk."2.68Hypertension and borderline isolated systolic hypertension increase risks of cardiovascular disease and mortality in male physicians. ( Ajani, U; Berger, K; Glynn, RJ; Hennekens, CH; Manson, JE; O'Donnell, CJ; Ridker, PM, 1997)
" This study was aimed at: evaluating the magnitude and incidence of the inhibitory phenomenon; defining the minimal aspirin dosage that produces an antagonistic effect, as well as the possible reasons for a different individual susceptibility."2.68[The antagonistic effect of aspirin on the expression of prostaglandin participation in the antihypertensive activity of ACE inhibitors]. ( Alimento, M; Campodonico, J; Celeste, F; Guazzi, M; Rossi, M; Santambrogio, G; Trabattoni, D, 1997)
" Further dosage adjustments are made in accordance with a set protocol."2.67The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results. ( Hansson, L; Zanchetti, A, 1994)
" In conclusion, treatment with dihydropyridines alone or in combination with low-dose aspirin can prevent circadian increases in platelet activity in patients with essential hypertension."2.67Effects of dihydropyridines and their combination with aspirin on blood pressure and circadian platelet activity in patients with essential hypertension. ( Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L, 1994)
"Captopril treatment significantly increased the urinary excretion of PGE2 (P = 0."2.67Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril. ( Coffman, TM; Smith, SR; Svetkey, LP, 1993)
"The incidence of preeclampsia was lower in the aspirin group (69 of 1485 women [4."2.67Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Caritis, SN; Klebanoff, M; McNellis, D; Paul, RH; Rocco, L; Romero, R; Rosen, M; Sibai, BM; Thom, E; Witter, F, 1993)
"Preeclampsia affects up to 8% of pregnancies worldwide and remains a major cause of maternal and neonatal morbidity and mortality."2.66Novel Interventions for the Prevention of Preeclampsia. ( Costantine, MM; Kniss, D; Ma'ayeh, M; Rood, KM, 2020)
"Preeclampsia is considered a specific disease of pregnancy, but recent theories suggest that women suffering from the condition have greater propensity to develop atherosclerosis, heart disease, and stroke over the years."2.66Analyzing Preeclampsia as the Tip of the Iceberg Represented by Women with Long-Term Cardiovascular Disease, Atherosclerosis, and Inflammation. ( Diniz, AD; Diniz, ALD; Paes, MMBM, 2020)
"Preeclampsia is an obstetric disorder that affects 3-8% of pregnant women and remains a leading cause of short- and long-term neonatal and maternal morbidity and mortality."2.66Prevention of preeclampsia. ( Costantine, MM; Ma'ayeh, M, 2020)
"Chronic hypertension affects 1-5% of women of childbearing age."2.66Aspirin for the prevention of placenta-mediated complications in pregnant women with chronic hypertension. ( Haddad, B; Lecarpentier, E, 2020)
"Women with chronic hypertension have a higher incidence of superimposed preeclampsia, cesarean section, preterm delivery before 37 weeks' gestation, birth weight less than 2500 g, neonatal unit admission, and perinatal death."2.66Hypertension During Pregnancy. ( Agrawal, A; Wenger, NK, 2020)
"The aspirin effect was the same across all risk-factor groups."2.66Controlled trial of aspirin in cerebral ischemia: an addendum. ( Fields, WS; Gary, HE; Lemak, NA, 1986)
"Aspirin has been shown to acutely block the natriuretic effect of spironolactone in the mineralocorticoid-treated normal rat, dog, and man."2.64Failure of aspirin to antagonize the antihypertensive effect of spironolactone in low-renin hypertension. ( Hollifield, JW, 1976)
"Pregnancy-induced hypertension is a major cause of maternal and fetal morbidity and mortality."2.61Hypertension and Pregnancy: Management and Future Risks. ( Jim, B; Reddy, S, 2019)
" Efficacy outcomes included ischemic stroke, stent thrombosis, major adverse cardiovascular event (MACE), all-cause mortality and myocardial infarction (MI); safety outcome was major bleeding."2.58Efficacy and safety of triple therapy versus dual antiplatelet therapy in patients with atrial fibrillation undergoing coronary stenting: A meta-analysis. ( Huang, J; Liu, L; Tang, X; Zhang, X, 2018)
"Preeclampsia is a hypertensive disorder of pregnancy that remains a significant cause of maternal morbidity and mortality worldwide."2.53Aspirin vs Heparin for the Prevention of Preeclampsia. ( Kanellopoulou, T; Katsi, V; Makris, T; Nihoyannopoulos, P; Nomikou, E; Tousoulis, D, 2016)
"Aspirin has higher side effect risks and requires a longer time to achieve benefit."2.52Primary prevention: do the very elderly require a different approach? ( Schwartz, JB, 2015)
" Careful attention must be paid to the dosing and potential teratogenicity of medications."2.52Pregnancy and Lupus Nephritis. ( Garovic, VD; Kattah, AG, 2015)
"Avoiding hypoglycemia is most important for elderly patients with long history of diabetes and atherosclerosis."2.49[Cardiovascular event in elderly patients with diabetes mellitus]. ( Nomura, K, 2013)
"However, unlike stroke, treatment of hyperlipidemia with statin class drugs or treatment of blood clotting abnormalities with acetylsalicylic acid do not appear to have an effect on VaD incidence or progression."2.48Pharmacological prevention and treatment of vascular dementia: approaches and perspectives. ( Baskys, A; Cheng, JX, 2012)
"Careful counseling of women with diabetic nephropathy before pregnancy with estimation of the risk for the mother and fetus is important."2.48Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment. ( Clausen, P; Damm, P; Feldt-Rasmussen, B; Mathiesen, ER; Ringholm, L, 2012)
"Preeclampsia is a pregnancy-associated illness affecting multiple organ systems."2.44[Anesthetic management of parturients with pre-eclampsia and eclampsia]. ( Bremerich, DH; Fetsch, NI, 2008)
"The Metabolic syndrome is a widely prevalent and multi-factorial disorder."2.43Metabolic syndrome. ( Agarwal, PK; Gogia, A, 2006)
"Cardiovascular diseases are the major cause of death and a significant cause of disability in the Western world and more recently threaten to pose an increasing health burden on developing nations."2.43Drug therapies in the secondary prevention of cardiovascular diseases: Successes, shortcomings and future directions. ( Grewal, J; Lonn, E, 2006)
"Those with existing hypertension are more likely to see a blood pressure elevation, although the magnitude of the effect is less predictable and may vary with age, baseline blood pressure, type of NSAID and concurrent antihypertensive therapy."2.43The effect of non-steroidal anti-inflammatory drugs and other commonly used non-narcotic analgesics on blood pressure level in adults. ( Poulter, NR; Wilson, SL, 2006)
"Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment."2.43Pathophysiology and medical management of systemic hypertension in preeclampsia. ( Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M, 2006)
"Therefore, prevention and treatment of diabetic nephropathy has become a prominent goal in the treatment of patients with diabetes mellitus."2.42Prevention and treatment of diabetic nephropathy in older patients. ( Jungmann, E, 2003)
"Stroke is a preventable tragedy for nearly 750,000 people each year."2.42Medical prevention of stroke, 2003. ( Kirshner, HS, 2003)
"Management of hypertension in diabetic nephropathy is challenging and generally requires a minimum of three different and complementary antihypertensive agents to achieve the recently recommended blood pressure (BP) goal of <130/80 mm Hg in order to reduce cardiovascular (CV) risk and preserve kidney function."2.42Diabetes and chronic kidney disease: tragedy and challenge. ( Bakris, GL; Chua, DY, 2004)
"Aspirin is the treatment of choice for stroke prevention in patients who do not require anticoagulation."2.42Transient ischemic attacks: Part II. Treatment. ( Solenski, NJ, 2004)
"Paroxysmal AF is an important cause of brain embolism, that is often difficult to document."2.42Atrial fibrillation and cardioembolic stroke. ( Ferro, JM, 2004)
"Vascular dementia is one of the most frequently occurring dementia syndromes."2.42[Vascular dementia]. ( de Leeuw, FE; van Gijn, J, 2004)
" Thus, bedtime, but not morning, dosing with cilnidipine significantly reduces nocturnal blood pressure."2.42Chronotherapy of hypertension. ( Hermida, RC; Smolensky, MH, 2004)
"Stroke is a major cause of morbidity and mortality."2.41A benefit-risk assessment of agents used in the secondary prevention of stroke. ( MacWalter, RS; Shirley, CP, 2002)
"Aspirin has a modest effect on reducing stroke."2.41[Antithrombotic therapy for stroke prevention in patients with atrial fibrillation]. ( Kitabatake, A; Kohya, T; Tomita, F, 2000)
"Diabetes mellitus is another CHD risk factor which is stronger in women than in men, and CHD death rates are 3-7 times greater among diabetic than nondiabetic women."2.40Risk factors for coronary heart disease in women. ( Hennekens, CH, 1998)
" Long term administration of "antiplatelet drugs" to affect the rate of development of atherosclerosis seems neither feasible nor desirable."2.37The role of platelets in the development and complications of atherosclerosis. ( Mustard, JF; Packham, MA, 1986)
"Normal human pregnancy is characterized by vascular refractoriness to AII."2.36Control of vascular responsiveness during human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1980)
"To explore the ATF2 expression of preeclampsia patients and investigate whether the level of ATF2 expression impacted the low-dose aspirin treatment of preeclampsia patients."1.91Low-dose Aspirin may Prevent Preeclampsia by Inhibiting the Expression of ATF2. ( Guo, L; Hu, R; Liu, R; Xiao, S; Zhang, M, 2023)
" This study aimed to evaluate the effects of long-term administration of losartan, aspirin, and atorvastatin on vascular remodeling in juvenile spontaneously hypertensive rats (SHRs)."1.91Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats. ( Dong, B; Dong, S; Li, L; Liu, Q; Shen, J; Yang, K; Zhao, Y; Zhou, X; Zhu, D, 2023)
" Therefore, clinical and computational studies have proposed optimizing antihypertensive medications' dosing time (Ta)."1.91Understanding the dosing-time-dependent antihypertensive effect of valsartan and aspirin through mathematical modeling. ( Cortés-Ríos, J; Rodriguez-Fernandez, M, 2023)
"When aspirin and α-blocker were used simultaneously, it could lower the risk of lung cancer significantly (HR: 0."1.62Antihypertensive treatments and risks of lung Cancer: a large population-based cohort study in Hong Kong. ( Lam, ASM; Li, J; Tsoi, KKF; Yau, STY; Yiu, KKL, 2021)
"In Western European countries, acute ischemic stroke (AIS) remains the third leading cause of death."1.62Risk factors among stroke subtypes and its impact on the clinical outcome of patients of Northern Portugal under previous aspirin therapy. ( Freitas-Silva, M; Medeiros, R; Nunes, JPL, 2021)
"Aspirin was prescribed in 99."1.56Baseline clinical characteristics and patient profile of the TURKMI registry: Results of a nation-wide acute myocardial infarction registry in Turkey. ( Akboğa, M; Aktaş, I; Aladağ, N; Arın, CB; Asoğlu, R; Deveci, OS; Doğan, A; Dural, M; Erol, MK; Güneş, Y; Ince, O; Kayıkçıoğlu, M; Kılıçkap, M; Kurt, IH; Örnek, E; Özkan, E; Şen, T; Sinan, ÜY; Somuncu, MU; Tüner, H; Yenerçağ, M; Zeybey, U, 2020)
"Objectives A "potential drug-drug interaction" (pDDI) is the possibility one drug has to alter the effects of another when both are administered simultaneously."1.56Potential drug-drug interactions in ICU patients: a retrospective study. ( Ali, I; Bazzar, A; Hussein, N; Sahhar, E, 2020)
"Simultaneous occurrence of transient global amnesia and Takotsubo syndrome has been only rarely reported."1.51Simultaneous transient global amnesia and Takotsubo syndrome after death of a relative: a case report. ( Finsterer, J; Stollberger, C, 2019)
": The prevalence of hypertension, type 2 diabetes mellitus (DM2) and the metabolic syndrome continues to increase in Latin America, while the rates of diagnosis, treatment and control of these disorders remain low."1.51Latin American Consensus on the management of hypertension in the patient with diabetes and the metabolic syndrome. ( Accini, JL; Alcocer, L; Barbosa, E; Camacho, PA; Cobos, L; Coca, A; Diaz, M; Lanas, F; López-Jaramillo, P; Molina, DI; Pasquel, M; Ponte-Negretti, CI; Sanchez, R; Sebba-Barroso, W; Wyss, F; Zanchetti, A, 2019)
"Hypertension was reported in 14."1.51Arterial occlusive events in chronic myeloid leukemia patients treated with ponatinib in the real-life practice are predicted by the Systematic Coronary Risk Evaluation (SCORE) chart. ( Abruzzese, E; Albano, F; Annunziata, M; Attolico, I; Baratè, C; Binotto, G; Bonifacio, M; Breccia, M; Caocci, G; Castagnetti, F; Cattaneo, D; De Gregorio, F; Elena, C; Foà, R; Fozza, C; Galimberti, S; Gozzini, A; Gugliotta, G; Iurlo, A; La Nasa, G; Luciano, L; Mulas, O; Orlandi, EM; Pirillo, F; Pregno, P; Scaffidi, L; Scalzulli, E; Sgherza, N; Stagno, F; Trawinska, MM, 2019)
"Aspirin is an effective, low cost option to reduce cardiovascular events."1.51Aspirin Use for Cardiovascular Disease Prevention in an African American Population: Prevalence and Associations with Health Behavior Beliefs. ( Duval, S; Eder, M; Jones, C; Luepker, RV; Misialek, JR; Oldenburg, NC; Van't Hof, JR, 2019)
"Aspirin was the most commonly used drug, some hypertensive patients were taking aspirin without being on concomitant antihypertensive drugs."1.51Inappropriate drug use in the elderly outpatient population in a West-African metropolitan community
. ( Amao, O; Arikawe, A; Megbuwawon, T; Ogunyemi, A; Olusanya, A, 2019)
"Hypertension is a metabolic disease which is caused by vasoconstriction and that results into elevated blood pressure."1.48Role of Acetyl Salicylic Acid in Controlling the DOCA-Salt Induced Hypertension in Rats by Stimulating the Synthesis of r-Cortexin in the Kidney. ( Chatterjee, M; Ghosh, TK; Jana, P; Karmakar, S; Maji, UK; Saha, A, 2018)
"The cohort of women with a history of preeclampsia were divided into 2 groups, before and after the release of the US Preventive Services Task Force 2014 recommendations."1.46Impact of USPSTF recommendations for aspirin for prevention of recurrent preeclampsia. ( Aagaard, KM; Chu, DM; Hollier, LM; Mastrobattista, JM; Racusin, DA; Ramin, SM; Sangi-Haghpeykar, H; Tolcher, MC, 2017)
"The rate of preeclampsia was much higher at quintile (Q) 5 of VAT depth (9."1.46Preeclampsia and Preterm Birth Associated With Visceral Adiposity in Early Pregnancy. ( Berger, H; Bujold, E; Connelly, PW; De Souza, LR; Park, AL; Ray, JG, 2017)
"Treatment with aspirin alone [hazard ratio (HR), 0."1.46Efficacy of aspirin and statins in primary prevention of cardiovascular mortality in uncomplicated hypertensive participants: a Korean national cohort study. ( Choi, D; Kang, SM; Kim, HC; Lee, CJ; Lee, SH; Oh, J; Park, S, 2017)
"The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present."1.43Evaluation of potential drug- drug interactions among Palestinian hemodialysis patients. ( Abu-Ghazaleh, D; Al-Ramahi, R; Bsharat, A; Raddad, AR; Rashed, AO; Shehab, O; Yasin, E, 2016)
"Aspirin resistance was detected in 22 (16."1.40Hypertension as a risk factor for aspirin and clopidogrel resistance in patients with stable coronary artery disease. ( Akturk, IF; Caglar, FN; Caglar, IM; Erturk, M; Surgit, O; Tuncer, N; Uzun, F; Yalcın, AA, 2014)
"Patients with a history of cerebral hemorrhage were excluded."1.40Associations of durations of antiplatelet use and vascular risk factors with the presence of cerebral microbleeds. ( Hattori, N; Okuma, Y; Tanaka, R; Tanaka, Y; Ueno, Y; Urabe, T; Yamashiro, K, 2014)
"adults have a heart attack or stroke, resulting in approximately 30 deaths every hour and, for nonfatal events, often leading to long-term disability."1.40Million hearts: prevalence of leading cardiovascular disease risk factors--United States, 2005-2012. ( George, MG; Gillespie, C; Jamal, A; Ritchey, MD; Wall, HK, 2014)
"Diagnosis of benign paroxysmal positional vertigo (BPPV) often causes difficulties, in particular, in elderly people with concomitant diseases."1.40[Benign paroxysmal positional vertigo in a female with arterial hypertension and meningioma]. ( Bestuzheva, NV; Parfenov, VA; Zamergrad, MV, 2014)
"While a stroke or transient ischemic attack or history of systemic thromboembolism was detected in 15."1.39Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study. ( Acar, G; Akıl, MA; Arıbaş, A; Aydın, M; Bilik, MZ; Bulur, S; Cağlıyan, CE; Ergene, O; Ertaş, F; Gedik, S; Gül, M; Kahya Eren, N; Kanadaşı, M; Kaya, H; Kaya, Z; Köroğlu, B; Köse, N; Oylumlu, M; Ozhan, H; Simşek, Z; Ulgen, MS; Vatan, B; Yeter, E; Yıldız, A; Yılmaz, R; Yüksel, M, 2013)
"Superimposed preeclampsia occurred in 49 (23."1.39Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy. ( Cabrol, D; Goffinet, F; Haddad, B; Lecarpentier, E; Sibai, B; Tsatsaris, V, 2013)
"Hypertension is the most important modifiable risk factor for intracerebral hemorrhage (ICH), but blood pressure (BP) management during the acute phase of ICH is still controversial."1.38The effect of admission blood pressure on the prognosis of patients with intracerebral hemorrhage that occurred during treatment with aspirin, warfarin, or no drugs. ( Asil, T; Balci, K; Celik, Y; Ir, N; Tekinaslan, I; Unlu, E; Utku, U, 2012)
"Losartan is known to inhibit transforming growth factor β signaling and may be a specific modulator of disease expression in this syndrome."1.37Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. ( Levinson, JR; MacRae, CA; Nahed, BV; Naunheim, MR; Ogilvy, CS; Walcott, BP, 2011)
"Pretreatment with cilostazol (100 mg/kg) significantly reduced infarct size."1.36Cilostazol, a phosphodiesterase inhibitor, attenuates photothrombotic focal ischemic brain injury in hypertensive rats. ( Hashimoto, A; Ito, H; Matsumoto, Y; Miyakoda, G; Yao, H, 2010)
"Hypertension is a common risk factor for peripheral arterial disease (PAD)."1.36Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy. ( Anderson, RD; Bavry, AA; Cooper-Dehoff, RM; Denardo, SJ; Gong, Y; Handberg, EM; Pepine, CJ, 2010)
"Aspirin use was reported in 50% of patients: 68."1.36Aspirin use in elderly women receiving medication therapy management services. ( Cooke, CE; Lee, HY; Tong, YP; Xing, S, 2010)
"Hypertension was untreated in 125 patients (33."1.35Secondary prevention of coronary artery disease in urban Indian primary care. ( Gupta, R, 2009)
"The occurrence of superimposed preeclampsia should be detected by appropriate clinical and laboratory evaluation."1.35[Arterial hypertension in pregnancy]. ( Leeman, M, 2008)
"We report a patient who presented with transient ischemic attack (TIA) associated with stenosis of the accessory MCA ostium."1.35Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report. ( Gao, F; Jiang, WJ, 2009)
"Aspirin treated hypertensives showed a significant reduction of sP-selectin (-26%, p<0."1.35In vivo platelet activation is responsible for enhanced vascular endothelial growth factor levels in hypertensive patients. ( Basili, S; D'Alessandro, R; Davì, G; Ferroni, P; Guadagni, F; Magnapera, A; Martini, F; Raparelli, V; Scarno, A, 2008)
" The present study investigated the importance of endogenous prostaglandin production and nitric oxide (NO) in the renal haemodynamic and excretory responses to ischaemia-reperfusion both normally and in the hypertensive state by chronic administration of cyclo-oxygenase (COX) inhibitors."1.35Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation. ( Johns, EJ; Knight, S, 2008)
"Aspirin was the most frequently prescribed adjoining non-anti-hypertensive drugs (39."1.33Pattern of drug utilization among hypertensives in a Nigerian teaching hospital. ( Balogun, OB; Yusuff, KB, 2005)
"Rofecoxib also reduced cardiac hypertrophy."1.33Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. ( de Champlain, J; Laplante, MA; Wu, R, 2005)
"Aspirin responders were defined when closure time was > or =300 s."1.33Prevalence of aspirin resistance in patients with type 2 diabetes. ( Bocksch, W; Cabeza, N; Dietz, R; Ersel, S; Fateh-Moghadam, S; Gawaz, M; Htun, P; Plöckinger, U; Reuter, T, 2005)
"Hypertension was defined as self-reported blood pressure of 140/90 mm Hg or higher or use of antihypertensive medication."1.33Analgesic use and risk of subsequent hypertension in apparently healthy men. ( Buring, JE; Gaziano, JM; Glynn, RJ; Hennekens, CH; Kurth, T; Sesso, HD; Stürmer, T, 2005)
"Overweight and obesity are well-established risk factors for cardiovascular disease and decline in kidney function in individuals with existing chronic kidney disease (CKD)."1.33Association between body mass index and CKD in apparently healthy men. ( Buring, JE; Gaziano, JM; Gelber, RP; Kausz, AT; Kurth, T; Levey, AS; Manson, JE, 2005)
"The progress of leukoaraiosis is greatly inhibited by long-term correction of platelet hyper-aggregability."1.33Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability. ( Fujita, S; Fukushima, K; Kawaguchi, T; Uehara, T, 2005)
"Hypertension is also one of the major atherosclerotic risk factors."1.33Aspirin therapy as primary prevention in hypertensive patients at Srinagarind hospital. ( Bumrerraj, S; Choenrungroj, T; Kosakarn, J; Limpawattana, P; Naranunn, P; Pradit, P; Premgamone, A; Punyamee, S; Sawanyawisuth, K; Thongmee, A, 2005)
"But aspirin therapy was used in only 35 cases (32."1.33The rate of checking urine microalbumin and aspirin primary prevention in type 2 DM. ( Limpawattana, P; Mahankkanukrauh, A; Sawanyawisuth, K; Wongvipaporn, C, 2006)
"Hypertension was induced in adult male Wistar rats using Methylprednisolone (MP) 20 mg/kg per week s."1.32Potential adverse interaction between aspirin and lisinopril in hypertensive rats. ( Balani, DK; Dubey, K; Pillai, KK, 2003)
" The drug's effect as well as adverse effects should be actively sought, and dosage alterations made in order to enhance the drug's effect."1.32Introduction to monitoring. What is what you prescribed actually doing? ( George, A; Shakib, S, 2003)
"Dyslipidemia is associated with macular exudates and vision loss."1.32Preventing diabetic retinopathy through control of systemic factors. ( Fong, D; Jain, A; Sarraf, D, 2003)
"Only clonidine treatment totally prevented the development of insulin resistance, and high-dose aspirin, known to prevent insulin resistance by inhibition of the activity of IkappaB kinase-beta, decreased the degree of insulin resistance by almost 70%."1.32Hypertension and insulin resistance are not directly related in obese dogs. ( Gokee, A; Rocchini, AP; Yang, JQ, 2004)
"Hypertension was a more common risk factor in AS patients (69% AS patients vs."1.32Risk factors and in-hospital outcomes in stroke and myocardial infarction patients. ( Ivanusa, M; Ivanusa, Z, 2004)
"The purpose of treating hypertension is prevention of cardiovascular diseases."1.31[Pharmacological prevention of cardiovascular diseases in general practice]. ( Ellekjaer, H; Gjelsvik, B; Hetlevik, I; Holmen, J; Kimsås, A; Meland, E, 2000)
"Aspirin was used regularly by 37% of those with CVD and by 13% of those with risk factors only Adjusted odds of regular aspirin use were significantly greater for individuals with CVD than for those with one CVD risk factor (odds ratio [OR] = 4."1.31Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey. ( Fagot-Campagna, A; Narayan, KM; Rolka, DB, 2001)
"No patients with preeclampsia or other severe complications of pregnancy were observed in the normalised group."1.31Late normalisation of uterine artery velocimetry in high risk pregnancy. ( Danti, L; Frusca, T; Scalvi, L; Soregaroli, M; Valcamonico, A, 2001)
"Severe bleeding was defined by the need for admission to hospital."1.31Characteristics of patients with antiphospholipid syndrome with major bleeding after oral anticoagulant treatment. ( Castellino, G; Cuadrado, MJ; Godfrey, T; Hughes, GR; Khamashta, MA, 2001)
"2."1.31Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats. ( del Soldato , P; Dicay, M; Lovren, F; McKnight, W; Muscará, MN; Triggle, CR; Wallace, JL, 2001)
"A dry bothersome cough is the most common adverse class effect of all angiotensin-converting enzyme inhibitors (ACE-I)."1.31The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings. ( Fisman, EZ; Motro, M; Pines, A; Shapira, I; Tenenbaum, A, 2001)
"History of untreated hypertension prior to the initial stroke (RR = 1."1.30Stroke recurrence among 30 days survivors of ischemic stroke in a prospective community-based study. ( Baranska-Gieruszczak, M; Czlonkowska, A; Hier, DB; Lechowicz, W; Ryglewicz, D, 1997)
"Treatment with aspirin, beta blockers, and angiotensin converting enzyme inhibitors."1.30Secondary prevention in coronary heart disease: baseline survey of provision in general practice. ( Campbell, NC; Deans, HG; Rawles, JM; Ritchie, LD; Thain, J, 1998)
" Next, by drawing on data from the HOT trial, the mixture and dosage of drugs for each level of blood pressure control were estimated."1.30Cost effectiveness of intensive treatment of hypertension. Based on presentations by Donald S. Shepard, PhD; and Dominic Hodgkin, PhD. ( , 1998)
"Pulmonary edema was rare and acute renal failure did not develop in any women."1.30Safety of labor epidural anesthesia for women with severe hypertensive disease. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. ( Caritis, SN; Dombrowski, MP; Hauth, JC; Hogg, B; Klebanoff, M; Landon, M; Lindheimer, M; MacPherson, C; McNellis, D; Meis, PJ; Miodovnik, M; Paul, R; Roberts, JM; Sibai, BM; Thurnau, GR; Van Dorsten, JP, 1999)
"To study treatment of hypertension in pregnancy in Sweden and compare our results with a similar study published in 1981."1.29How Swedish obstetricians manage hypertensive disorders in pregnancy. A questionnaire study. ( Ingemarsson, I; Montal, S; Wide-Swensson, D, 1994)
"Advanced age, previous stroke or transient ischemic attack (TIA), hypertension and diabetes were all found to be risk factors for stroke in patients with atrial fibrillation."1.29[Atrial fibrillation and apoplexy--risks and prevention]. ( Gulløv, AL; Koefoed, BG; Petersen, P, 1996)
"Hypertension is a known risk factor in the genesis of coronary artery disease."1.28Influence of mild to moderate treated hypertension on 9-11 year mortality in patients with pre-existing coronary heart disease. ( Gupta, KD; Gupta, R; Kasliwal, P, 1992)
"The value of treatment of hyperlipidemia in reducing the incidence of a first stroke remains to be demonstrated."1.28Ischemic stroke. How to keep the first one from happening. ( Bundlie, SR, 1991)
"Arterial hypertension was found in 78 of 224 consecutive patients operated for nasal polyposis."1.28Nasal polyposis as a risk factor for hypertension. ( Granström, G; Jacobsson, E; Jeppsson, PH, 1990)
"Endothelin (i."1.28Endothelin-induced sudden death and the possible involvement of platelet activating factor (PAF). ( Imura, Y; Iwasaki, K; Nishikawa, K; Shibouta, Y; Terashita, Z, 1989)

Research

Studies (820)

TimeframeStudies, this research(%)All Research%
pre-199089 (10.85)18.7374
1990's176 (21.46)18.2507
2000's283 (34.51)29.6817
2010's194 (23.66)24.3611
2020's78 (9.51)2.80

Authors

AuthorsStudies
Ernst, ME2
Fravel, MA1
Webb, KL1
Wetmore, JB1
Wolfe, R2
Chowdhury, E1
Reid, CM3
Woods, RL2
Beilin, L1
Margolis, KL2
Murray, AM1
Polkinghorne, KR1
Yang, J2
Mo, S1
Wang, K1
Liu, Q3
Wu, J2
Yang, S1
Guo, R1
Yang, Y2
Zhang, J7
Liu, Y4
Jiang, P1
Cao, Y2
Wang, S1
Bahit, MC1
Sacco, RL1
Easton, JD1
Meyerhoff, J1
Cronin, L1
Kleine, E1
Grauer, C1
Brueckmann, M1
Diener, HC3
Lopes, RD2
Brainin, M1
Lyrer, P2
Wachter, R1
Segura, T1
Granger, CB3
Li, J3
Lam, ASM1
Yau, STY1
Yiu, KKL1
Tsoi, KKF1
Ray, JG3
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Terashita, Z1
Shibouta, Y1
Imura, Y1
Iwasaki, K1
Nishikawa, K1
Borhani, NO2
Dekker, GA1
Makovitz, JW1
Rotmans, P1
Elder, MG1
de Swiet, M1
Robertson, A1
Elder, MA1
Flloyd, E1
Hawkins, DF1
Davenport, J1
Whittaker, K1
Bernardi, P1
Bastagli, L1
Cavazza, M1
Minelli, C1
Ventura, C1
Fontana, F1
Danieli, A1
Bartolini, G1
Tommasi, V1
Orlandi, M1
Rubin, PC1
Horn, L1
Cox, SM1
Quilley, CP2
Chiba, S1
Packham, MA1
Mustard, JF1
Lemak, NA1
Fields, WS1
Gary, HE1
Lavie, CJ1
Squires, RW1
Gau, GT1
Greer, IA1
Walker, JJ1
Forbes, CD1
Calder, AA1
Katori, M1
Hori, Y1
Uchida, Y1
Tanaka, K1
Harada, Y1
Ogawa, K1
Ito, T1
Anwer, K1
Woo, OF1
Benowitz, NL1
Bialy, FW1
Wengert, JW1
Hamazaki, T1
Hasunuma, K1
Kobayashi, S1
Shishido, H1
Yano, S1
Rubin, JR1
Goldstone, J1
Flower, RJ1
Somova, L1
Petkov, O1
Orbetsova, V1
Allen, JE1
Valeri, CR1
Nakano, J1
el-Dakhakhny, M1
el-Sayed, M1
Bailey, RR1
Neale, TJ1
Little, PJ1
Petruson, B1
Bologna, E1
Vroom, FQ2
Greenhouse, AH1
Laborit, H1
Valette, N1
Burry, HC1
Wolinsky, H1
Goldfischer, S1
Schiller, B1
Kasak, LE1
Paolini, JP1
Lendvay, LJ1
Heare, CR1

Clinical Trials (60)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aspirin in Reducing Events in the Elderly[NCT01038583]19,114 participants (Actual)Observational2010-01-31Active, not recruiting
Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embol[NCT02239120]Phase 35,390 participants (Actual)Interventional2014-11-27Completed
Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II[NCT04078737]Phase 36,412 participants (Actual)Interventional2019-09-23Completed
Evaluation of Platelet Effects of Chlorthalidone and Hydrochlorothiazide[NCT02100462]Phase 430 participants (Anticipated)Interventional2014-03-31Recruiting
ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925]Phase 311,140 participants (Actual)Interventional2001-06-30Completed
A Prospective Muti-center Study of Early Prediction and Randomised Prevention of Preeclampsia With Low Dose Aspirin in Chinese Cohort[NCT04631627]Phase 41,500 participants (Anticipated)Interventional2020-11-16Not yet recruiting
The Effects of Aspirin in Gestation and Reproduction: A Multi-center, Controlled, Double-blind Randomized Trial.[NCT00467363]1,228 participants (Actual)Interventional2007-06-30Completed
The Impact of Meal Timing on Neurovascular Control in Adults[NCT04133701]34 participants (Actual)Interventional2022-02-02Completed
A Retrospective Epidemiological Study to Map Out Patients With Chronic Obstructive Pulmonary Disease (COPD) and Describe COPD Health Care in Real-Life Primary Care During the First Ten Years of the 21th Century[NCT01146392]27,394 participants (Actual)Observational2010-06-30Completed
Effectiveness of the Timing of the Administration of Aspirin in Hypertensive Patients Treated With Low Doses of Acetyl Salicylic Acid for Secondary Prevention - TAHPS[NCT01741922]Phase 3230 participants (Actual)Interventional2012-12-31Completed
Japanese Primary Prevention Project With Aspirin in the Elderly With One or More Risk Factors of Vascular Events: JPPP[NCT00225849]Phase 410,000 participants Interventional2005-03-31Recruiting
The Northwest Coalition for Primary Care Practice Support[NCT02839382]209 participants (Actual)Interventional2015-05-01Completed
USE OF KEFIR AS A CO-ADJUVANT IN THE TREATMENT OF METABOLIC SYNDROME COMPONENTS: a Double-blind, Randomized, Placebo Controlled Clinical Trial[NCT03649828]48 participants (Actual)Interventional2016-07-01Completed
Effects of Synbiotics Supplementation on the Concentration of the Uremic Toxin Indoxyl Sulfate, Symptoms of Constipation, and Constipation-related Quality of Life in End-stage Renal Disease Patients Undergoing Hemodialysis[NCT04527640]60 participants (Anticipated)Interventional2020-09-15Not yet recruiting
A Multi-center, Randomized, Double-blind and Placebo-controlled Clinical Research of 2200 Cases in Improving Curative Effect of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM[NCT02334969]Phase 42,200 participants (Actual)Interventional2016-04-30Completed
The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin[NCT03869268]Phase 472 participants (Actual)Interventional2019-04-24Completed
Aspirin Withdrawal and Clinical Outcome in Patients With Moderate to High Cardiovascular Risk But Without Cardiovascular Disease[NCT03757156]4,118 participants (Anticipated)Interventional2019-03-31Not yet recruiting
Evaluation of Some Emerging Biomarkers of Cardiovascular Risk Stratification in Hypertensive Patients: a 5-years Follow-up[NCT02064218]0 participants Observational2007-11-30Recruiting
Comparison of Age-related Macular Degeneration Treatments Trials: Lucentis-Avastin Trial (CATT)[NCT00593450]Phase 31,208 participants (Actual)Interventional2008-02-29Completed
Secondary Prevention of Small Subcortical Strokes (SPS3) Trial[NCT00059306]Phase 33,020 participants (Actual)Interventional2003-02-28Completed
Acetylsalicylic Acid Administered in Patients With Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System[NCT03341117]Phase 321 participants (Actual)Interventional2014-12-02Completed
Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479]Phase 339,876 participants (Actual)Interventional1992-09-30Completed
Prognostic Value of Ambulatory Blood Pressure Monitoring in the Prediction of Cardiovascular Events and Effects of Chronotherapy in Relation to Risk (the MAPEC Study).[NCT00295542]Phase 43,344 participants (Actual)Interventional2000-03-31Completed
Aspirin AM or PM in Reduction of Tension: a Randomized Cross-over Trial[NCT01379079]Phase 4290 participants (Actual)Interventional2011-04-30Completed
INternational VErapamil SR Trandolapril STudy[NCT00133692]Phase 422,000 participants Interventional1997-09-30Completed
Perioperative Blood Pressure and In-hospital Morbidity After Coronary Artery Bypass Surgery[NCT05192005]1,220 participants (Anticipated)Observational2023-04-15Not yet recruiting
A Randomized, Double-Blind, Parallel Group, Multicenter Study to Evaluate the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180 mg Compared to Placebo Added to Background Lipid-Modifying Therapy in Patients With Elevated LDL-C Who Are Statin Intolerant[NCT02988115]Phase 3345 participants (Actual)Interventional2016-11-16Completed
TEC4Home Stroke - Assessing the Feasibility of Home Telemonitoring Technology in Managing Hypertension Among Stroke/TIA Patients. Pilot Study at Vancouver Stroke Program in Collaboration With TEC4Home Heart Failure Team[NCT03712033]50 participants (Actual)Observational2018-03-01Completed
Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial[NCT05580523]3,000 participants (Anticipated)Interventional2023-07-03Recruiting
Influence of the Autonomic Nervous System on Endothelial Function as an Acute Response to Exercise in Hypertensive Individuals: a Randomized Double-blind Protocol Study[NCT04371757]39 participants (Anticipated)Interventional2020-04-30Recruiting
Effectiveness of Polypill for Primary Prevention of Cardiovascular Disease (PolyPars): Study Design and Rationale for a Pragmatic Cluster Randomized Controlled Trial[NCT03459560]Phase 34,415 participants (Actual)Interventional2015-12-20Active, not recruiting
A Randomised Controlled Cross-over Trial to Evaluate Evening Versus Morning Administration of a Cardiovascular Polypill[NCT01506505]78 participants (Actual)Interventional2012-07-31Completed
Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119]Phase 4200 participants (Anticipated)Interventional2018-12-11Recruiting
Nurses' Health Study (Cardiovascular Component)[NCT00005152]121,700 participants (Actual)Observational1980-08-31Active, not recruiting
The Nueva Ecija Cardiovascular Risk Experiment: An Evaluation of the Impact of Risk Information and Screening on Primary Prevention of Cardiovascular Disease[NCT03512691]5,019 participants (Anticipated)Interventional2018-01-20Recruiting
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: An Intervention Study[NCT01480804]48 participants (Actual)Interventional2006-11-30Completed
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: A Cost-effective Intervention Study[NCT01486290]52 participants (Actual)Interventional2007-07-31Completed
Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy[NCT00287651]Phase 2/Phase 3150 participants (Actual)Interventional2005-11-30Terminated (stopped due to Administrative)
Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF: The CORRAL-AF Study[NCT04684212]2,931 participants (Anticipated)Interventional2023-12-01Not yet recruiting
Prevalence of Aspirin Resistance in Ischemic Stroke Patients at Assiut University Hospital[NCT05151263]133 participants (Anticipated)Observational2023-11-01Not yet recruiting
A Multi-center, Double-Blind Randomized, Cross-over, Active-control, Comparative Clinical Study to Evaluate the Administration Time-dependent Antihypertensive Effects of Low Dose Aspirin in Well-Controlled Hypertensive Patients (Phase IV)[NCT00386529]Phase 4191 participants (Actual)Interventional2006-09-30Completed
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260]Phase 3496 participants (Actual)Interventional1995-06-30Completed
Clinical Feature and Outcome of Angiographic Coronary Artery Disease in Chronic Kidney Disease Patients[NCT00651521]1,000 participants (Actual)Observational2009-04-30Active, not recruiting
[NCT00000482]Phase 30 participants Interventional1965-04-30Completed
Influence of ACE Genotype on Lung Diffusion at Rest and After Fluid Overload in Heart Failure Patients Treated With ACE-inhibitors[NCT00361127]100 participants (Actual)Interventional2006-08-31Completed
Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney Disease[NCT00874432]Phase 243 participants (Actual)Interventional2009-01-31Completed
A Pivotal Study To Evaluate The Effectiveness of Isometric Handgrip Therapy In Prehypertensive And Hypertensive Patients[NCT04467879]146 participants (Actual)Interventional2020-06-01Terminated (stopped due to New Protocol and Outcome Measures in Review)
Influence of SPRINT Trial Type Blood Pressure Measurements on Hypertension Diagnosis in Patients After Kidney Transplantation[NCT03094702]120 participants (Actual)Observational2017-01-01Completed
Efficacy and Tolerability of Combination Antihypertensive Drug in Non-Responders to Angiotensin Receptor Blocker(ARB) monoTHerapy Using 24h ABPM.[NCT01713920]Phase 468 participants (Actual)Interventional2010-04-30Completed
MRI Evaluation of Nidus Occlusion After Gamma Knife Radiosurgery of Cerebral Arteriovenous Malformations - A Prospective Preliminary Study[NCT03995823]50 participants (Anticipated)Observational2019-07-01Recruiting
A Comparison of Fetal Hemodynamic Measurements Between Pregnant Women Taking Anti-hypertensive Medication and Controls[NCT00759278]0 participants (Actual)Observational2008-08-31Withdrawn (stopped due to No participants)
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial[NCT04855513]414 participants (Anticipated)Interventional2022-03-24Not yet recruiting
Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia In Patients Undergoing Elective Thyroidectomy. A Randomized Controlled Study[NCT04471597]48 participants (Actual)Interventional2020-07-20Completed
Do Innovative Strategies Complement Medical Management to Reduce Cardiovascular Risk Factors Following Coronary Artery Bypass Graft Surgery?[NCT00462436]Phase 235 participants (Anticipated)Interventional2007-02-28Completed
Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University[NCT03266328]117 participants (Anticipated)Observational2017-09-01Not yet recruiting
A Randomized, Double-Blind Trial to Test Higher- Versus Lower-Doses of Aspirin on Inflammatory Markers and Platelet Biomarkers and Nitric Oxide Formation in High Risk Primary Prevention (Patients With Metabolic Syndrome)[NCT00272311]Phase 470 participants (Actual)Interventional2006-10-31Completed
A Randomized, Double-Blind Trial to Test Higher- Versus Lower-Doses of Aspirin on Inflammatory Markers and Platelet Biomarkers and Nitric Oxide Formation & Endothelial Function in Secondary Prevention (Pts w/Chronic Stable Coronary Disease)[NCT00272337]Phase 437 participants (Actual)Interventional2006-10-31Completed
Efficacy of Medifast's 5 & 1 Program Compared to a Food-based Diet After a Period of Weight Loss and Weight Maintenance[NCT01011491]90 participants (Actual)Interventional2008-03-31Completed
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680]11,976 participants (Actual)Interventional2016-03-23Completed
Prevention of Preeclampsia With Aspirin Administered From the Beginning of Pregnancy in Recipients of Donated Oocytes.[NCT02174328]Phase 381 participants (Actual)Interventional2014-05-21Terminated (stopped due to Halted prematurely due to low recruitment rate.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adjudicated Composite of Non-fatal Stroke, Non-fatal Myocardial Infarction, or Cardiovascular Death

Adjudicated composite of non-fatal stroke, non-fatal myocardial infarction (MI), or cardiovascular death is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)4.80
Acetylsalicylic Acid, Aspirin (ASA) 100 mg5.40

Adjudicated Fatal Bleed

Adjudicated fatal bleeding was defined as a bleeding event which the Independent Event Adjudication Committee (IAC) determined as the primary cause of death or contributed directly to death. The annualised event rate represents the average number of events per patient during a 1-year period. Because there were 0 events in one treatment group, the hazard ratio is unable to be calculated. (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.00
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.05

Adjudicated Intracranial Hemorrhage

"Adjudicated intracranial haemorrhage comprised the subtypes of intracerebral bleeds, intraventricular bleeds, subdural bleeds, epidural bleeds, and subarachnoid bleeds. Microbleeds did not qualify as intracranial haemorrhage, except when they were symptomatic.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.67
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.63

Adjudicated Ischaemic Stroke

Adjudicated ischaemic stroke is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)3.97
Acetylsalicylic Acid, Aspirin (ASA) 100 mg4.71

Adjudicated Life-threatening Bleed

"Major bleeds were to be classified as life-threatening if they met one or more of the following criteria: fatal bleed, symptomatic intracranial bleed, reduction in haemoglobin of at least 5 grams/ deciliter (g/dL), transfusion of at least 4 units of packed red blood cells (equivalent to 9 units in Japan), associated with hypotension requiring the use of intravenous inotropic agents, or necessitated surgical intervention.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.76
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.91

Adjudicated Recurrent Stroke

Adjudicated recurrent stroke (ischemic, hemorrhagic, or unspecified) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, approximately 43 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)4.09
Acetylsalicylic Acid, Aspirin (ASA) 100 mg4.80

All-cause Death

All-cause death is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)1.24
Acetylsalicylic Acid, Aspirin (ASA) 100 mg1.28

Any Bleed (Investigator-reported)

"This was the sum of all major and minor bleeds (Minor bleeds were clinical bleeds that did not fulfil the criteria for major bleeds), regardless of severity.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)15.21
Acetylsalicylic Acid, Aspirin (ASA) 100 mg11.64

Disabling Stroke

Disabling stroke (modified Rankin Scale greater than or equal to 4, as determined 3 months after recurrent stroke) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.55
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.93

First Major Bleed (Adjudicated)

"First major bleed is primary safety endpoint. Major bleeds were defined according to the International Society of Thrombosis and Haemostasis (ISTH) definition as follows:~Symptomatic bleeding in a critical area or organ, such as intracranial, intraspinal, intraocular, retroperitoneal, intra-articular or pericardial, or intramuscular with compartment syndrome and/or,~Bleeding (which should be overt) associated with a reduction in haemoglobin of at least 2 grams/ decilitre (g/dL) (1.24 millimoles Per Litre (mmol/L)), or leading to transfusion of ≥2 units of blood or packed cells (equivalent to ≥4.5 units in Japan); the haemoglobin drop should be considered to be due to and temporally related to the bleeding event and/or,~Fatal bleed. The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)1.84
Acetylsalicylic Acid, Aspirin (ASA) 100 mg1.33

Abruption

Partial or complete abruption (ie, premature separation of the placenta) (NCT00467363)
Timeframe: until delivery

Interventionparticipants (Number)
Aspirin7
Placebo5

Clinically Recognized Pregnancy

(NCT00467363)
Timeframe: 8-weeks

Interventionpregnancy (Number)
Aspirin374
Placebo346

Early Pregnancy Loss (EPL)

Implantation failures (NCT00467363)
Timeframe: 8 weeks

Interventionpregnancy (Number)
Aspirin28
Placebo27

Ectopic Pregnancy

(NCT00467363)
Timeframe: within 6 weeks

Interventionpregnancy (Number)
Aspirin3
Placebo3

Fetal Pregnancy Loss

(NCT00467363)
Timeframe: until 40 weeks

Interventionpregnancy (Number)
Aspirin4
Placebo6

hCG Recognized Pregnancy

(NCT00467363)
Timeframe: within 8-weeks of gestation

Interventionpregnancy (Number)
Aspirin394
Placebo363

Live Birth

Live birth was obtained prospectively by maternal report and abstraction from medical records by trained staff . (NCT00467363)
Timeframe: after delivery

Interventionlivebirths (Number)
Aspirin309
Placebo286

Molar Pregnancy

(NCT00467363)
Timeframe: 8 weeks

Interventionpregnancy (Number)
Aspirin0
Placebo0

Preeclampsia

(NCT00467363)
Timeframe: until delivery

Interventionparticipants (Number)
Aspirin32
Placebo30

Pregnancy Losses Occurring Less Than 10 Weeks

Includes preembryonic and embryonic losses (exclusive of implantation failures) (NCT00467363)
Timeframe: less than 10-weeks

Interventionpregnancy (Number)
Aspirin56
Placebo53

Preterm Birth

(NCT00467363)
Timeframe: until delivery

Interventioninfants (Number)
Aspirin22
Placebo31

Small for Gestational Age Infant

birthweight (NCT00467363)
Timeframe: until delivery

Interventiongrams (Mean)
Aspirin3327
Placebo3315

Stillbirth

(NCT00467363)
Timeframe: 40 weeks

Interventionparticipants (Number)
Aspirin2
Placebo2

Area of Lesion

(NCT00593450)
Timeframe: at 1 Year

Interventionmm^2 (Mean)
1-Lucentis Monthly6.6
2-Avastin Monthly6.5
3-Lucentis as Needed7.3
4-Avastin as Needed7.0

Area of Lesion Change From Baseline

(NCT00593450)
Timeframe: Baseline and 1 Year

Interventionmm^2 (Mean)
1-Lucentis Monthly-0.1
2-Avastin Monthly0.3
3-Lucentis as Needed0.6
4-Avastin as Needed1.3

Average Cost of Drug/Patient

(NCT00593450)
Timeframe: at 1 Year

InterventionUS dollars per patient (Mean)
1-Lucentis Monthly23400
2-Avastin Monthly595
3-Lucentis as Needed13800
4-Avastin as Needed385

Change From Baseline in Visual-acuity Score (Continuous)

"Visual acuity testing was performed with the Electronic Visual Tester (EVA) following the ETDRS protocol. VA score is measured as number of letters read correctly. The VA score change is the difference of the VA score at 1 Year and the VA score at baseline.~In this study, the outcome VA score change is ranged from -71 to 52, with the higher VA score change the better visual acuity improvement." (NCT00593450)
Timeframe: Baseline and 1 Year

InterventionNo. of Letters (Mean)
1-Lucentis Monthly8.5
2-Avastin Monthly8.0
3-Lucentis as Needed6.8
4-Avastin as Needed5.9

Change in Diastolic Blood Pressure From Baseline

(NCT00593450)
Timeframe: Baseline and 1 Year

Interventionmm Hg (Mean)
1-Lucentis Monthly-0.9
2-Avastin Monthly-1.4
3-Lucentis as Needed-1.9
4-Avastin as Needed-2.1

Change in Systolic Blood Pressure From Baseline

(NCT00593450)
Timeframe: Baseline and 1 Year

Interventionmm Hg (Mean)
1-Lucentis Monthly-2.1
2-Avastin Monthly-5.4
3-Lucentis as Needed-5.2
4-Avastin as Needed-4.5

Number of Treatments

Cumulative over the 1 year of trial (NCT00593450)
Timeframe: 1 Year

InterventionNumber of Treatments (Mean)
1-Lucentis Monthly11.7
2-Avastin Monthly11.9
3-Lucentis as Needed6.9
4-Avastin as Needed7.7

Retinal Thickness Plus Subfoveal-fluid Thickness at Fovea

(NCT00593450)
Timeframe: at 1 Year

Interventionμm (Mean)
1-Lucentis Monthly152
2-Avastin Monthly172
3-Lucentis as Needed166
4-Avastin as Needed172

Retinal Thickness Plus Subfoveal-fluid Thickness Change From Baseline at Fovea

(NCT00593450)
Timeframe: Baseline and 1 Year

Interventionμm (Mean)
1-Lucentis Monthly-100
2-Avastin Monthly-79
3-Lucentis as Needed-81
4-Avastin as Needed-79

Total Thickness at Fovea

(NCT00593450)
Timeframe: at 1 Year

Interventionμm (Mean)
1-Lucentis Monthly266
2-Avastin Monthly300
3-Lucentis as Needed294
4-Avastin as Needed308

Total Thickness Change From Baseline at Fovea

(NCT00593450)
Timeframe: Baseline and 1 Year

Interventionμm (Mean)
1-Lucentis Monthly-196
2-Avastin Monthly-164
3-Lucentis as Needed-168
4-Avastin as Needed-152

Visual-acuity Score and Snellen Equivalent (Continuous)

"Visual acuity testing was performed with the Electronic Visual Tester (EVA) following the ETDRS protocol. VA score is measured as number of letters read correctly.~In this study, the outcome VA score is ranged from 0 to 97, with the higher score the better visual acuity." (NCT00593450)
Timeframe: at 1 Year

InterventionNo. of Letters (Mean)
1-Lucentis Monthly68.8
2-Avastin Monthly68.4
3-Lucentis as Needed68.4
4-Avastin as Needed66.5

Change From Baseline Visual-acuity Score (Frequency)

(NCT00593450)
Timeframe: Baseline and 1 Year

,,,
InterventionParticipants (Number)
Increase of ≥15 lettersIncrease of 5-14 lettersChange of ≤4 lettersDecrease of 5-14 lettersDecrease of ≥15 letters
1-Lucentis Monthly9790621916
2-Avastin Monthly8398501816
3-Lucentis as Needed71103752313
4-Avastin as Needed7690592323

Dye Leakage on Angiogram

(NCT00593450)
Timeframe: at 1 Year

,,,
InterventionParticipants (Number)
AbsentPresentData missing
1-Lucentis Monthly1679720
2-Avastin Monthly15310012
3-Lucentis as Needed13313715
4-Avastin as Needed11114515

Fluid on Optical Coherence Tomography

(NCT00593450)
Timeframe: at 1 Year

,,,
InterventionParticipants (Number)
AbsentPresentData missing
1-Lucentis Monthly1241519
2-Avastin Monthly691888
3-Lucentis as Needed6820314
4-Avastin as Needed522145

Visual-acuity Score and Snellen Equivalent (Frequency)

(NCT00593450)
Timeframe: at 1 Year

,,,
InterventionParticipants (Number)
83-97 letters, 20/12-2068-82 letters, 20/25-4053-67 letters, 20/50-8038-52 letters, 20/100-160≤37 letters, ≤20/200
1-Lucentis Monthly42149522318
2-Avastin Monthly45134472118
3-Lucentis as Needed38141662317
4-Avastin as Needed40127572423

Number of Participants With Cancer, Excluding Nonmelanoma Skin Cancer

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
Interventionparticipants (Number)
Total invasive cancerCancer death
Aspirin + Vitamin E716152
Aspirin Only722132
Both Placebos706143
Vitamin E Only721156

Number of Participants With Major Cardiovascular Events (a Combined Endpoint of Nonfatal Myocardial Infarction, Nonfatal Stroke, and Total Cardiovascular Death)

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
InterventionParticipants (Number)
Major cardiovascular eventStrokeMyocardial infarctionCardiovascular death
Aspirin + Vitamin E23210810254
Aspirin Only2451139666
Both Placebos2721339974
Vitamin E Only2501339452

Percent Change From Baseline (PCFB) in Low-density Lipoprotein Cholesterol (LDL-C) at Week 12

PCFB was calculated as the ([post-Baseline (BL) value minus the BL value] divided by the BL value ) x 100. BL was defined as the mean of the last two non-missing values on or prior to Day 1. If only one value was available, that single value was used as BL. PCFB in LDL-C was analyzed using analysis of covariance (ANCOVA), with treatment group and stratification factor (primary prevention; secondary prevention) as fixed effects and BL as a covariate. For participants with missing lipid data at Week 12 who were no longer taking study treatment, missing values were imputed using multiple imputation via a regression-based model including stratification and BL data from placebo participants only. In this imputation model, treatment group was not included. For participants with missing lipid data at Week 12 who were still taking study treatment, missing values were imputed using multiple imputation via a regression-based model including treatment, stratification and BL value. (NCT02988115)
Timeframe: Baseline; Week 12

Interventionpercent change (Least Squares Mean)
Bempedoic Acid-22.58
Placebo-1.17

Percent Change From Baseline in High-Sensitivity C-Reactive Protein (hsCRP) at Week 12

Percent change from Baseline was calculated as the ([post-Baseline value minus the Baseline value] divided by the Baseline value) x 100. Baseline for hsCRP is defined as the last non-missing value on or prior to Day 1. Percent change from Baseline in hsCRP, non-parametric (Wilcoxon rank-sum test) analysis with Hodges-Lehmann estimates and confidence interval was performed. (NCT02988115)
Timeframe: Baseline; Week 12

Interventionpercent change (Median)
Bempedoic Acid-25.37
Placebo2.67

Percent Change From Baseline in LDL-C at Week 24

PCFB was calculated as the ([post-BL value minus the BL value] divided by the BL value ) x 100. BL was defined as the mean of the last two non-missing values on or prior to Day 1. If only one value was available then that single value was used as BL. PCFB in LDL-C was analyzed using ANCOVA, with treatment group and stratification factor (primary prevention; secondary prevention) as fixed effects and BL as a covariate. For participants with missing lipid data at Week 12 who were no longer taking study treatment, missing values were imputed using multiple imputation via a regression-based model including stratification and BL data from placebo participants only. In this imputation model, treatment group was not included. For participants with missing lipid data at Week 12 who were still taking study treatment, missing values were imputed using multiple imputation via a regression-based model including treatment, stratification and BL value. (NCT02988115)
Timeframe: Baseline; Week 24

Interventionpercent change (Least Squares Mean)
Bempedoic Acid-21.17
Placebo-2.26

Absolute Change From Baseline in LDL-C at Week 12 and Week 24

Change from Baseline is calculated as the ([post-Baseline value minus the Baseline value] divided by the Baseline value ) x 100. Baseline is defined as the mean of the last two non-missing values on or prior to Day 1. (NCT02988115)
Timeframe: Baseline; Week 12; Week 24

,
Interventionmg/dL (Mean)
Week 12Week 24
Bempedoic Acid-39.3-37.0
Placebo-3.1-5.1

Percent Change From Baseline in the Lipid Profile at Week 12

PCFB was calculated as: ([post-BL value minus the BL value] divided by the BL value) x 100. BL was defined as the mean of the last two non-missing values on or prior to Day 1. If only one value was available, that single value was used as BL. apoB and TC BL were defined as the last non-missing value on/prior to Day 1. PCFB was analyzed using ANCOVA, with treatment and group stratification factor (primary prevention; secondary prevention) as fixed effects and BL as a covariate. For participants with missing data at Week 12 who were no longer taking study treatment (ST), missing values were imputed using multiple imputation via a regression-based model including stratification and BL data from placebo participants only. In this imputation model, treatment group was not included. For participants with missing lipid data at Week 12 who were still taking ST, missing values were imputed using multiple imputation via a regression-based model including treatment, stratification and BL value. (NCT02988115)
Timeframe: Baseline; Week 12

,
Interventionpercent change (Least Squares Mean)
non-HDL-CTCapoB
Bempedoic Acid-18.08-15.37-14.65
Placebo-0.14-0.610.32

Aortic Pulse Wave Velocity (PWV)

PWV will be measured in patients over age 60 with stage 3 CKD and age matched controls without CKD. (NCT00874432)
Timeframe: up to 12 months

,
Interventionm/s (Mean)
Carotid-Femoral Pulse Wave VelocityCarotid-Brachial Pulse Wave VelocityCarotid-Radial Pulse Wave Velocity
Age Matched Control9.968.578.38
Chronic Kidney Disease9.907.629.03

Mean Vascular Stiffness As Measured by PWV

"Comparison between Participants with Stage 3 Chronic Kidney Disease (CKD) and age matched Controls without CKD. The numbers reported are the mean of all the participants in the group at two points in time - the baseline and at 12 months for CFPWV, CBPWV, and CRPWV.~Carotid-Femoral Pulse Wave Velocity (CFPWV) Carotid-Brachial Pulse Wave Velocity (CBPWV) Carotid-Radial Pulse Wave Velocity (CRPWV)" (NCT00874432)
Timeframe: baseline and 12 months

,,,
Interventionm/s (Mean)
CBPWV BaselineCBPWV 12 monthsCRPWV BaselineCRPWV 12 monthsCFPWV BaselineCFPWV 12 months
Age Matched Control8.178.068.959.439.559.79
Age Matched Control-ACE-I9.148.659.758.169.968.33
Chronic Kidney Disease6.288.284.808.667.9510.66
Chronic Kidney Disease-ACE-I7.878.409.038.5710.2011.07

Change in Nitric Oxide Formation From Baseline to 3 Months

Changes in Heme oxygenase (HO-1) a downstream target of nitric oxide (NO) formation. (NCT00272311)
Timeframe: Baseline to 3 Months (90-97 days)

Interventionng/mL (Mean)
Arm 1 of 5 Randomized Treatment Arms27.6
Arm 2 of 5 Randomized Treatment Arms27.0
Arm 3 of 5 Randomized Treatment Arms31.4
Arm 4 of 5 Randomized Treatment Arms25.7
Arm 5 of 5 Randomized Treatment Arms28.3

Change in Nitric Oxide Formation From Baseline to 3 Months.

Heme oxygenase a downstream target of nitric oxide formation (NCT00272337)
Timeframe: Baseline to 3 Months (90-97 days)

Interventionng/mL (Mean)
1 of 5 Randomized Treatment Arms10.0
2 of 5 Randomized Treatment Arms11.2
3 of 5 Randomized Treatment Arms10.0
4 of 5 Randomized Treatment Arms11.0
5 of 5 Randomized Treatment Arms9.6

Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks)

- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm189
Placebo Arm230

Fetal Outcome 2 - Incidence of Actual Birth Weight <2500g

- Birth weight <2500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm1078
Placebo Arm1153

Fetal Outcome 3 - Incidence of Actual Birth Weight <1500g

- Birth weight <1500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm78
Placebo Arm101

Fetal Outcome 4 - Incidence of Fetal Loss

- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm303
Placebo Arm353

Fetal Outcome 5 - Incidence of Spontaneous Abortion

- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm134
Placebo Arm152

Fetal Outcome 6 - Incidence of All Stillbirth

- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm141
Placebo Arm166

Fetal Outcome 7 - Incidence of Medical Termination of Pregnancy

- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm42
Placebo Arm30

Incidence of Hypertensive Disorders of Pregnancy

- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)

InterventionParticipants (Count of Participants)
Intervention Arm352
Placebo Arm325

Incidence of Perinatal Mortality

- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm264
Placebo Arm309

Incidence of Preterm Birth

The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm668
Placebo Arm754

Incidence of Small for Gestational Age (SGA)

- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm1506
Placebo Arm1564

Maternal Outcome 1 - Incidence of Vaginal Bleeding

- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm214
Placebo Arm246

Maternal Outcome 2 - Incidence of Antepartum Hemorrhage

- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm26
Placebo Arm25

Maternal Outcome 3 - Incidence of Postpartum Hemorrhage

- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm54
Placebo Arm43

Maternal Outcome 4 - Incidence of Maternal Mortality

- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm9
Placebo Arm12

Maternal Outcome 5 - Incidence of Late Abortion

- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm23
Placebo Arm30

Maternal Outcome 6 - Change in Maternal Hemoglobin

Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.

InterventionParticipants (Count of Participants)
Intervention Arm290
Placebo Arm333

Maternal Outcome 7 - Incidence of Preterm, Preeclampsia

Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm8
Placebo Arm21

Reviews

187 reviews available for aspirin and Blood Pressure, High

ArticleYear
Screening for preeclampsia in twin pregnancies.
    Best practice & research. Clinical obstetrics & gynaecology, 2022, Volume: 84

    Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Trimeste

2022
Antiplatelet agents and anticoagulants for hypertension.
    The Cochrane database of systematic reviews, 2022, 07-28, Volume: 7

    Topics: Aged; Anticoagulants; Aspirin; Clopidogrel; Fibrinolytic Agents; Hemorrhage; Humans; Hypertension; M

2022
Low-dose aspirin for the prevention of superimposed preeclampsia in women with chronic hypertension: a systematic review and meta-analysis.
    American journal of obstetrics and gynecology, 2023, Volume: 228, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Perinatal Death; Pre-Eclampsia; Pregnancy; P

2023
Pre-eclampsia.
    Nature reviews. Disease primers, 2023, 02-16, Volume: 9, Issue:1

    Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Perinatal Death; Pre-Eclampsia; Pregnancy; P

2023
Aspirin and Pravastatin for Preeclampsia Prevention in High-Risk Pregnancy.
    Obstetrics and gynecology clinics of North America, 2023, Volume: 50, Issue:1

    Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Pravastatin; Pre-Eclampsia; Pregnancy; Pregn

2023
Cardiac medications in obstetric patients.
    Current opinion in cardiology, 2023, 05-01, Volume: 38, Issue:3

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Agents; Female; Hematologic Agents; Humans; Hyperte

2023
Role of aspirin in the prevention of preeclampsia in previously hypertensive pregnant women: A Meta-Analysis.
    JPMA. The Journal of the Pakistan Medical Association, 2023, Volume: 73, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pr

2023
Polygenic prediction of preeclampsia and gestational hypertension.
    Nature medicine, 2023, Volume: 29, Issue:6

    Topics: Aspirin; Child; Eclampsia; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Pre-Eclamp

2023
Novel Interventions for the Prevention of Preeclampsia.
    Current hypertension reports, 2020, 02-12, Volume: 22, Issue:2

    Topics: Animals; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Pre-

2020
Analyzing Preeclampsia as the Tip of the Iceberg Represented by Women with Long-Term Cardiovascular Disease, Atherosclerosis, and Inflammation.
    Current atherosclerosis reports, 2020, 02-19, Volume: 22, Issue:3

    Topics: Aspirin; Atherosclerosis; Female; Humans; Hypertension; Inflammation; Placenta; Placentation; Pre-Ec

2020
Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly.
    Current cardiology reports, 2020, 05-29, Volume: 22, Issue:7

    Topics: Aged; Aspirin; Cardiovascular Diseases; Case-Control Studies; Diabetes Complications; Diabetes Melli

2020
Prevention of preeclampsia.
    Seminars in fetal & neonatal medicine, 2020, Volume: 25, Issue:5

    Topics: Aspirin; Female; Fibrinolytic Agents; Humans; Hypertension; Pre-Eclampsia; Pregnancy

2020
Pregnancy and cardiovascular disease.
    Nature reviews. Cardiology, 2020, Volume: 17, Issue:11

    Topics: Acute Coronary Syndrome; Antihypertensive Agents; Aortic Dissection; Arrhythmias, Cardiac; Aspirin;

2020
Aspirin for the prevention of placenta-mediated complications in pregnant women with chronic hypertension.
    Journal of gynecology obstetrics and human reproduction, 2020, Volume: 49, Issue:9

    Topics: Aspirin; Female; France; Humans; Hypertension; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complic

2020
Toward personalized management of chronic hypertension in pregnancy.
    American journal of obstetrics and gynecology, 2022, Volume: 226, Issue:2S

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure Monitoring, Ambulatory; Calcium; Chronic Disease; C

2022
Hypertension During Pregnancy.
    Current hypertension reports, 2020, 08-27, Volume: 22, Issue:9

    Topics: Aspirin; Cesarean Section; Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Pregnancy;

2020
Hypertensive Disorders of Pregnancy.
    Clinics in perinatology, 2020, Volume: 47, Issue:4

    Topics: Anticonvulsants; Antihypertensive Agents; Aspirin; Chronic Disease; Delivery, Obstetric; Eclampsia;

2020
Family History of Hypertension, Cardiovascular Disease, or Diabetes and Risk of Developing Preeclampsia: A Systematic Review.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2021, Volume: 43, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Female; Humans; Hypertension; Pre-Eclam

2021
Aspirin for Primary Prevention.
    The Medical clinics of North America, 2017, Volume: 101, Issue:4

    Topics: Age Factors; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Diabetes Mellitus; Gastrointest

2017
Efficacy and safety of triple therapy versus dual antiplatelet therapy in patients with atrial fibrillation undergoing coronary stenting: A meta-analysis.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Combinations; Drug-Related Side Effects and Adverse

2018
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis

2019
Hypertension and Pregnancy: Management and Future Risks.
    Advances in chronic kidney disease, 2019, Volume: 26, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Diuretics; Female; Human

2019
Polypills for primary prevention of cardiovascular disease.
    Nature reviews. Cardiology, 2019, Volume: 16, Issue:10

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Coronary Disease; Drug Combinations; Huma

2019
Closing the loop: a 21-year audit of strategies for preventing stroke and death following carotid endarterectomy.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2013, Volume: 46, Issue:2

    Topics: Angioscopy; Aspirin; Carotid Artery Diseases; Clinical Protocols; Clopidogrel; Drug Therapy, Combina

2013
Prevention of cardiovascular disease in women: highlights for the clinician of the 2011 American Heart Association Guidelines.
    Advances in chronic kidney disease, 2013, Volume: 20, Issue:5

    Topics: American Heart Association; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Cardiovascul

2013
Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association.
    Stroke, 2014, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Air Pollution; American Heart Association;

2014
[Cardiovascular event in elderly patients with diabetes mellitus].
    Nihon rinsho. Japanese journal of clinical medicine, 2013, Volume: 71, Issue:11

    Topics: Antihypertensive Agents; Aspirin; Atherosclerosis; Cardiovascular Diseases; Cause of Death; Clinical

2013
Cardiovascular disease and its relationship with chronic kidney disease.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:19

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Blood Pressure; Cardiovascular Diseases;

2014
Primary prevention: do the very elderly require a different approach?
    Trends in cardiovascular medicine, 2015, Volume: 25, Issue:3

    Topics: Aged, 80 and over; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Dementia; Humans; Hydr

2015
Pregnancy and Lupus Nephritis.
    Seminars in nephrology, 2015, Volume: 35, Issue:5

    Topics: Abortion, Spontaneous; Anticoagulants; Antihypertensive Agents; Antiphospholipid Syndrome; Aspirin;

2015
Platelets and Antiplatelet Therapy in Patients with Coronary Artery Disease and Diabetes.
    Seminars in thrombosis and hemostasis, 2016, Volume: 42, Issue:3

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Coronary Artery Disease; Diabetes Mellitus, Type 2; Hum

2016
Stroke Prevention in Atrial Fibrillation in Patients With Chronic Kidney Disease.
    Circulation, 2016, Apr-12, Volume: 133, Issue:15

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Creatinine; Diabetes C

2016
Atrial fibrillation.
    Nature reviews. Disease primers, 2016, 03-31, Volume: 2

    Topics: Ablation Techniques; Anticoagulants; Aspirin; Atrial Fibrillation; Dizziness; Dyspnea; Electric Coun

2016
Prevention of Hypertensive Disorders of Pregnancy: a Novel Application of the Polypill Concept.
    Current cardiology reports, 2016, Volume: 18, Issue:6

    Topics: Antihypertensive Agents; Aspirin; Calcium, Dietary; Drug Therapy, Combination; Female; Humans; Hyper

2016
The performance of risk prediction models for pre-eclampsia using routinely collected maternal characteristics and comparison with models that include specialised tests and with clinical guideline decision rules: a systematic review.
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:9

    Topics: Aspirin; Blood Pressure; Decision Support Techniques; Female; Fertilization; Humans; Hypertension; M

2016
Aspirin vs Heparin for the Prevention of Preeclampsia.
    Current hypertension reports, 2016, Volume: 18, Issue:7

    Topics: Aspirin; Female; Heparin; Humans; Hypertension; Placenta Diseases; Pre-Eclampsia; Pregnancy

2016
Vertebral artery dissection in hypertensive disorders of pregnancy: a case series and literature review.
    BMC pregnancy and childbirth, 2016, 07-16, Volume: 16, Issue:1

    Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure; Computed Tomography Angiography; Female; Hu

2016
Preventing deaths due to the hypertensive disorders of pregnancy.
    Best practice & research. Clinical obstetrics & gynaecology, 2016, Volume: 36

    Topics: Aspirin; Birth Intervals; Calcium; Cardiotocography; Dietary Supplements; Eclampsia; Female; Food Su

2016
Effects of Aspirin on Endothelial Function and Hypertension.
    Current hypertension reports, 2016, Volume: 18, Issue:11

    Topics: Animals; Aspirin; Clinical Trials as Topic; Endothelium, Vascular; Humans; Hypertension; Thrombosis;

2016
A practical "ABCDE" approach to the metabolic syndrome.
    Mayo Clinic proceedings, 2008, Volume: 83, Issue:8

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diet Therapy; Early Diagnosis; Evidence-Based M

2008
Cardiovascular disease prevention tailored for women.
    Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index; Cardiovascular Diseases; Choleste

2008
Aspirin for the primary prevention of cardiovascular events: a systematic review and meta-analysis comparing patients with and without diabetes.
    Diabetes care, 2009, Volume: 32, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Diabetic Angiopathies; Female; Fibrinolytic Agents; Humans; Hypert

2009
Antihypertensive effects of aspirin: what is the evidence?
    Current hypertension reports, 2010, Volume: 12, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Blood Pressure; Evidence-

2010
Vasoactive drugs for acute stroke.
    The Cochrane database of systematic reviews, 2010, Jul-07, Issue:7

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Aspirin; Blood Pressure; Hemoglobins; Humans;

2010
[Generation mechanisms and management strategies of adverse reactions to Bevacizumab during cancer treatment].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:7

    Topics: Angiogenesis Inhibitors; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Antibodie

2010
Prevention of stroke following transient ischemic attack.
    Current atherosclerosis reports, 2011, Volume: 13, Issue:4

    Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Brain; Carotid Stenosis; Clin

2011
Is it worth offering cardiovascular disease prevention to the elderly?
    European journal of preventive cardiology, 2013, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cost-Benefit Analysis; Diet; Exercise; Hu

2013
Antiplatelet agents and anticoagulants for hypertension.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Humans; Hypertension;

2011
Nonsteroidal antiinflammatory drugs, acetaminophen, and hypertension.
    Current hypertension reports, 2012, Volume: 14, Issue:4

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Cycloox

2012
Pharmacological prevention and treatment of vascular dementia: approaches and perspectives.
    Experimental gerontology, 2012, Volume: 47, Issue:11

    Topics: Alzheimer Disease; Antihypertensive Agents; Aspirin; Cholinesterase Inhibitors; Cognition; Dementia,

2012
Ambulatory management of chronic hypertension in pregnancy.
    Clinical obstetrics and gynecology, 2012, Volume: 55, Issue:3

    Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Disease

2012
Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:12

    Topics: Albuminuria; Antihypertensive Agents; Aspirin; Counseling; Diabetes Mellitus, Type 1; Diabetes Melli

2012
Long-term clinical experience with zofenopril.
    Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspirin; Captopril; Coro

2012
Potential cardioprotective actions of no-releasing aspirin.
    Nature reviews. Drug discovery, 2002, Volume: 1, Issue:5

    Topics: Animals; Apoptosis; Arteriosclerosis; Aspirin; Caspase Inhibitors; Cell Adhesion; Cyclic GMP; Cytoki

2002
The management of stroke patients by neurologists: common questions and new observations.
    Seminars in neurology, 2002, Volume: 22, Issue:1

    Topics: Angioplasty; Anticoagulants; Antihypertensive Agents; Aspirin; Carotid Stenosis; Case Management; Cl

2002
A benefit-risk assessment of agents used in the secondary prevention of stroke.
    Drug safety, 2002, Volume: 25, Issue:13

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Aspirin; Clinical

2002
Better stroke management.
    The Practitioner, 2002, Volume: 246, Issue:1639

    Topics: Aspirin; Female; Humans; Hypertension; Male; Platelet Aggregation Inhibitors; Practice Guidelines as

2002
Case report of paroxysmal atrial fibrillation and anticoagulation.
    BMJ (Clinical research ed.), 2002, Nov-02, Volume: 325, Issue:7371

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Attitude of Health Personnel; Attitude to Health; Comm

2002
[Aspirin in the primary prevention of the hypertensive patient].
    Revista clinica espanola, 2002, Volume: 202, Issue:12

    Topics: Aspirin; Female; Humans; Hypertension; Male; Primary Prevention; Warfarin

2002
Screening adults for type 2 diabetes: a review of the evidence for the U.S. Preventive Services Task Force.
    Annals of internal medicine, 2003, Feb-04, Volume: 138, Issue:3

    Topics: Adult; Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Evidence-Based Medicine; E

2003
Current management of hypertensive disease in pregnancy.
    East African medical journal, 2002, Volume: 79, Issue:4

    Topics: Anticonvulsants; Antihypertensive Agents; Aspirin; Calcium, Dietary; Delivery, Obstetric; Female; Hu

2002
Prevention and treatment of diabetic nephropathy in older patients.
    Drugs & aging, 2003, Volume: 20, Issue:6

    Topics: Aged; Albuminuria; Antihypertensive Agents; Aspirin; Blood Glucose; Clinical Trials as Topic; Diabet

2003
[Primary and secondary prevention of coronary artery disease].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2003, Volume: 94, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Aspir

2003
Choosing a drug from within a class.
    Australian family physician, 2003, Volume: 32, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Aspirin; Australia; Decision Making; Drug Costs;

2003
Medical prevention of stroke, 2003.
    Southern medical journal, 2003, Volume: 96, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Diet; Female; Humans; Hyp

2003
Primary prevention of coronary heart disease in the elderly.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:11

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Coronary Disease; Humans; Hypercholestero

2003
[Treatment of acute stroke -- an overview].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9

    Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cereb

2003
[Stroke prevention].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9

    Topics: Administration, Oral; Aged; Anticoagulants; Antihypertensive Agents; Aspirin; Carotid Stenosis; Cont

2003
Cardiovascular risk in patients with renal disease: treating the risk or treating the risk factor?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:1

    Topics: Adult; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Dietary Supplements; Folic Acid; H

2004
Stroke, dementia, and drug delivery.
    British journal of clinical pharmacology, 2004, Volume: 57, Issue:1

    Topics: Anticholesteremic Agents; Anticoagulants; Aspirin; Clinical Trials as Topic; Dementia; Fibrinolytic

2004
Diabetes and chronic kidney disease: tragedy and challenge.
    Blood purification, 2004, Volume: 22, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Blood Glucose; Calcium Channel Blocke

2004
Transient ischemic attacks: Part II. Treatment.
    American family physician, 2004, Apr-01, Volume: 69, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Aspirin; Female;

2004
[Renal and cardiovascular effects of non-steroidal anti-inflammatories and selective cox 2 inhibitors].
    Presse medicale (Paris, France : 1983), 2004, Apr-10, Volume: 33, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relations

2004
[Myocardial infarction in patients with hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Biomarkers; Creatine

2004
Atrial fibrillation and cardioembolic stroke.
    Minerva cardioangiologica, 2004, Volume: 52, Issue:2

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Comorbidity;

2004
[Vascular dementia].
    Nederlands tijdschrift voor geneeskunde, 2004, Jun-12, Volume: 148, Issue:24

    Topics: Aged; Aged, 80 and over; Arteriosclerosis; Aspirin; Cyclooxygenase Inhibitors; Dementia, Vascular; F

2004
Antiplatelet agents and anticoagulants for hypertension.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Humans; Hypertension;

2004
Chronotherapy of hypertension.
    Current opinion in nephrology and hypertension, 2004, Volume: 13, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Chronotherapy; Dose-Response Relationship, Drug; H

2004
Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.
    Circulation, 2004, Oct-19, Volume: 110, Issue:16

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cohort Studie

2004
[Inflammation and diabetes].
    MMW Fortschritte der Medizin, 2004, Sep-02, Volume: 146, Issue:35-36

    Topics: Adiponectin; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arte

2004
Stroke prevention.
    Clinical evidence, 2003, Issue:10

    Topics: Angioplasty, Balloon; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Humans;

2003
Prevention of cardiovascular events in diabetes.
    Clinical evidence, 2003, Issue:10

    Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Corona

2003
[Primary prevention of cardiovascular disease].
    Deutsche medizinische Wochenschrift (1946), 2005, Jan-07, Volume: 130, Issue:1-2

    Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Aspirin; Body Mass Index; Cardiovascular Diseases

2005
[Clinical guidelines for stroke].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Nov-10, Volume: 93, Issue:11

    Topics: Anticoagulants; Antipyrine; Arginine; Aspirin; Brain Edema; Edaravone; Fibrinolytic Agents; Free Rad

2004
Prevention of cardiovascular events in diabetes.
    Clinical evidence, 2004, Issue:11

    Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Corona

2004
Antithrombotic therapy in hypertension: a Cochrane Systematic review.
    Journal of human hypertension, 2005, Volume: 19, Issue:3

    Topics: Aspirin; Blood Pressure; Fibrinolytic Agents; Humans; Hypertension; Middle Aged; Thrombosis; Warfari

2005
Antiplatelet therapy and anticoagulation in patients with hypertension.
    American family physician, 2005, Mar-01, Volume: 71, Issue:5

    Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Humans; Hypertension; Platelet Aggregation Inhibi

2005
Stroke prevention.
    Clinical evidence, 2004, Issue:12

    Topics: Angioplasty, Balloon; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Drug Th

2004
Aspirin and endothelial function in hypertension.
    Journal of human hypertension, 2005, Volume: 19, Issue:9

    Topics: Aspirin; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hypertension

2005
Keeping the diabetic heart healthy.
    Australian family physician, 2005, Volume: 34, Issue:6

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Family Practice;

2005
Exercise rehabilitation in heart disease: the real "polypill" for primary and secondary prevention.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2005, Volume: 64, Issue:2

    Topics: Aspirin; Chronic Disease; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Exercise;

2005
Metabolic syndrome.
    Indian journal of medical sciences, 2006, Volume: 60, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Exercise; Humans; Hydroxymethylglutaryl

2006
[Acute coronary syndrome risk management].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:4

    Topics: Angina, Unstable; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Coronary Artery Disease; Humans

2006
Nonnarcotic analgesics and hypertension.
    The American journal of cardiology, 2006, May-08, Volume: 97, Issue:9A

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pre

2006
[Is it recommended simultaneous use of acetylsalicylic acid and angiotensin converting enzyme inhibitors?].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Pressure; Drug Antagonism; Drug Synergism;

2005
Incidence and management of bevacizumab-related toxicities in colorectal cancer.
    Expert opinion on drug safety, 2006, Volume: 5, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoa

2006
[Management of hypertension in patients with diabetes].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:6 Pt 2

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non

2006
Drug therapies in the secondary prevention of cardiovascular diseases: Successes, shortcomings and future directions.
    Current vascular pharmacology, 2006, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Atheroscler

2006
The effect of non-steroidal anti-inflammatory drugs and other commonly used non-narcotic analgesics on blood pressure level in adults.
    Journal of hypertension, 2006, Volume: 24, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antihyperte

2006
Stroke prevention in diabetes and obesity.
    Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atrial Fibrillation; Blood Glucose; Cardiovascular

2006
Prevention of cardiovascular events in diabetes.
    Clinical evidence, 2006, Issue:15

    Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Clopid

2006
Pathophysiology and medical management of systemic hypertension and pre-eclampsia in pregnancy.
    Minerva medica, 2006, Volume: 97, Issue:4

    Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure Determination; Calcium, Dietary; Chronic Dis

2006
The management of patients on anticoagulants prior to cutaneous surgery: case report of a thromboembolic complication, review of the literature, and evidence-based recommendations.
    Plastic and reconstructive surgery, 2006, Volume: 118, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Damage,

2006
[Guidelines for the management of atherosclerotic diseases in diabetes mellitus].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:11

    Topics: Aspirin; Atherosclerosis; Cardiovascular Diseases; Diabetes Complications; Dyslipidemias; Humans; Hy

2006
Pathophysiology and medical management of systemic hypertension in preeclampsia.
    Current hypertension reports, 2006, Volume: 8, Issue:6

    Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female

2006
[Screening and management of coronary artery disease in diabetic patients].
    La Tunisie medicale, 2006, Volume: 84, Issue:10

    Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inh

2006
[Overview of cardiovascular risk factors].
    Medicina clinica, 2006, Nov-25, Volume: 127, Issue:20

    Topics: Age Factors; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; As

2006
Coronary heart disease in patients with diabetes: part I: recent advances in prevention and noninvasive management.
    Journal of the American College of Cardiology, 2007, Feb-13, Volume: 49, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Agents; Coronary Disease; Diabetes

2007
Appropriate use of NSAIDs: considering cardiovascular risk in the elderly.
    Geriatrics, 2007, Volume: 62, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 In

2007
Confronting atrial fibrillation in the elderly: stroke risk stratification and emerging antithrombotic therapies.
    Geriatrics, 2007, Volume: 62, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Drug Evaluation; Drug Therapy, Combination; Fema

2007
Pharmacological prevention of atherothrombotic events in patients with peripheral arterial disease.
    European journal of clinical investigation, 2007, Volume: 37, Issue:3

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Agents; Diabetic Angiopathies; Humans; Hydroxymethy

2007
Independent predictors of stroke in patients with atrial fibrillation: a systematic review.
    Neurology, 2007, Aug-07, Volume: 69, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Case-Control Studies; Cohort Stu

2007
Quality indicators for the care of diabetes mellitus in vulnerable elders.
    Journal of the American Geriatrics Society, 2007, Volume: 55 Suppl 2

    Topics: Aged; Aspirin; Diabetes Complications; Diabetes Mellitus; Evidence-Based Medicine; Frail Elderly; Gl

2007
[Unrecognized myocardial infarction].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Sep-28, Volume: Suppl 5 Pt 2

    Topics: Adrenergic beta-Antagonists; Aging; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme In

2007
[Anesthetic management of parturients with pre-eclampsia and eclampsia].
    Der Anaesthesist, 2008, Volume: 57, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Aspirin; Blood Volume; Cesarean Section; Eclampsia; Female; Humans;

2008
The role of aspirin in cardiovascular prevention: implications of aspirin resistance.
    Journal of the American College of Cardiology, 2008, May-13, Volume: 51, Issue:19

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Drug Resistance; Heart Failure; Humans; Hyperte

2008
[Peripheral arterial disease--an underappreciated clinical problem].
    Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:4

    Topics: Age Factors; Aged; Ankle; Aspirin; Atherosclerosis; Brachial Artery; Diabetes Complications; Dyslipi

2008
Drug therapy of hypertension and ischaemic heart disease.
    British journal of anaesthesia, 1981, Volume: 53, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Antihypertensive Agents; Aspirin; Clofibrate; C

1981
[Peripheral arterial occlusions. Principles, possibilities and limits of conservative therapy].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Apr-10, Volume: 57, Issue:10

    Topics: Ancrod; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiomyopathies; Dextrans; Digitalis

1981
Control of vascular responsiveness during human pregnancy.
    Kidney international, 1980, Volume: 18, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hy

1980
Renal syndromes associated with nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1984, Mar-01, Volume: 310, Issue:9

    Topics: Acute Kidney Injury; Adult; Animals; Anti-Inflammatory Agents; Anuria; Aspirin; Body Water; Electrol

1984
Primary prevention of stroke.
    The New England journal of medicine, 1995, Nov-23, Volume: 333, Issue:21

    Topics: Aspirin; Cerebrovascular Disorders; Contraceptives, Oral; Diabetes Complications; Diet; Estrogen Rep

1995
The effects of nonsteroidal anti-inflammatory drugs on human hypertensive vascular disease.
    Seminars in nephrology, 1995, Volume: 15, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Drug Interactions; Humans; Hyperte

1995
Stroke prevention.
    Archives of neurology, 1995, Volume: 52, Issue:4

    Topics: Alcohol Drinking; Aspirin; Carotid Stenosis; Cerebrovascular Disorders; Clinical Trials as Topic; Di

1995
[Aspirin and pregnancy: present data and future perspectives].
    Contraception, fertilite, sexualite (1992), 1995, Volume: 23, Issue:3

    Topics: Aspirin; Controlled Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hypertension; Placent

1995
Hypertension in pregnancy.
    Canadian family physician Medecin de famille canadien, 1995, Volume: 41

    Topics: Antihypertensive Agents; Aspirin; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications,

1995
Is low-dose aspirin effective in preventing hypertension in pregnancy?
    Current opinion in nephrology and hypertension, 1994, Volume: 3, Issue:3

    Topics: Aspirin; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovasc

1994
[Pregnancy nephropathies].
    Presse medicale (Paris, France : 1983), 1993, Dec-04, Volume: 22, Issue:38

    Topics: Adult; Antihypertensive Agents; Aspirin; Epoprostenol; Female; Hemostasis; Humans; Hypertension; Kid

1993
Disordered eicosanoid formation in pregnancy-induced hypertension.
    Circulation, 1993, Volume: 88, Issue:3

    Topics: Aspirin; Eicosanoids; Epoprostenol; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications

1993
Incidence, natural history, and risk factors in lacunar infarction.
    Advances in neurology, 1993, Volume: 62

    Topics: Age Factors; Aged; Aspirin; Cardiovascular Diseases; Cerebral Infarction; Diabetic Angiopathies; Fem

1993
How can we best prolong life? Benefits of coronary risk factor reduction in non-diabetic and diabetic subjects.
    BMJ (Clinical research ed.), 1993, May-15, Volume: 306, Issue:6888

    Topics: Adult; Aspirin; Blood Pressure; Coronary Disease; Diabetes Mellitus; England; Humans; Hypercholester

1993
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
    Mayo Clinic proceedings, 1996, Volume: 71, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibri

1996
Management of postmyocardial infarction in the elderly patient.
    Clinics in geriatric medicine, 1996, Volume: 12, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Arrhyth

1996
Optimal management of chronic leg ulcers in the elderly.
    Drugs & aging, 1997, Volume: 10, Issue:5

    Topics: Administration, Oral; Aged; Aging; Arterial Occlusive Diseases; Aspirin; Bandages; Combined Modality

1997
Coronary heart disease: an older woman's major health risk.
    BMJ (Clinical research ed.), 1997, Oct-25, Volume: 315, Issue:7115

    Topics: Aged; Angina Pectoris; Aspirin; Cholesterol; Coronary Disease; Estrogen Replacement Therapy; Female;

1997
[Intervention in risk factors and protection of target organs].
    Anales de medicina interna (Madrid, Spain : 1984), 1997, Volume: 14, Issue:9

    Topics: Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Diabetes Complications; Diabetes Mellitus; Est

1997
[Late pregnancy toxicosis developing against a background of extragenital pathology and its prevention (a review)].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:10

    Topics: Adult; Aspirin; Female; Humans; Hypertension; Obesity; Pre-Eclampsia; Pregnancy; Risk Factors; Weigh

1997
Risk factors for coronary heart disease in women.
    Cardiology clinics, 1998, Volume: 16, Issue:1

    Topics: Aged; Antioxidants; Aspirin; Cholesterol; Contraceptives, Oral; Coronary Disease; Diabetes Mellitus;

1998
Vascular smooth muscle, endothelial regulation and effects of aspirin in hypertension.
    Frontiers in bioscience : a journal and virtual library, 1998, Apr-27, Volume: 3

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; Hypertension; Muscle, Sm

1998
[Primary prevention of coronary disease with drugs].
    La Revue du praticien, 1998, Jun-15, Volume: 48, Issue:12

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Coronary Disease; Fibrinolytic Agents; H

1998
Hypertension optimal treatment (HOT) study: a brilliant concept, but a qualified success.
    Journal of hypertension, 1998, Volume: 16, Issue:10

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combinatio

1998
Aggressive blood pressure lowering is safe, but benefit is still hard to prove.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti

1999
Counseling for women with preeclampsia or eclampsia.
    Seminars in perinatology, 1999, Volume: 23, Issue:1

    Topics: Aspirin; Calcium; Chronic Disease; Counseling; Eclampsia; Female; HELLP Syndrome; Humans; Hypertensi

1999
Heart disease in older patients.
    The Practitioner, 1998, Volume: 242, Issue:1589

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin;

1998
Definition of high blood pressure, epidemiology and goals of hypertension treatment.
    International journal of clinical practice. Supplement, 1998, Volume: 98

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure Determination; Coronary Disease; Europe; Humans; Hy

1998
Contemporary issues in heart failure.
    American heart journal, 1999, Volume: 138, Issue:1 Pt 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Anticoagulants; Aspirin; Communi

1999
Chronic hypertension in pregnancy.
    Annals of medicine, 1999, Volume: 31, Issue:4

    Topics: Abruptio Placentae; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin

1999
[Pharmacological prevention of gestation complications].
    Terapevticheskii arkhiv, 1999, Volume: 71, Issue:10

    Topics: Aspirin; Calcium, Dietary; Fatty Acids, Unsaturated; Female; Humans; Hypertension; Placental Insuffi

1999
Stroke. Preemptive strikes.
    Harvard health letter, 2000, Volume: 25, Issue:6

    Topics: Alcohol Drinking; Aspirin; Female; Hormone Replacement Therapy; Humans; Hypercholesterolemia; Hypert

2000
Update on the interaction between aspirin and angiotensin-converting enzyme inhibitors.
    Pharmacotherapy, 2000, Volume: 20, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clinical Trials as Topic; Coronary Disease; Drug

2000
[Antithrombotic therapy for stroke prevention in patients with atrial fibrillation].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:6

    Topics: Age Factors; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Diabetes Compli

2000
Other drug treatments: the evidence.
    The Proceedings of the Nutrition Society, 2000, Volume: 59, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspi

2000
Multiple risk factor intervention in type 2 diabetes: an opportunity not to be missed.
    Diabetes, obesity & metabolism, 2001, Volume: 3, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hypercho

2001
Should patients with hypertension receive antithrombotic therapy?
    Journal of internal medicine, 2001, Volume: 249, Issue:3

    Topics: Aspirin; Atrial Fibrillation; Fibrinolytic Agents; Hypertension; Myocardial Infarction; Risk Factors

2001
[Treatment of the massive suprachoroidal hemorrhages].
    Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blindness; Cataract Extraction; Comor

2001
Management of diabetic nephropathy.
    Journal of the Royal Society of Medicine, 2001, Volume: 94, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Diabetic Nephropathies;

2001
Does aspirin attenuate the effect of angiotensin-converting enzyme inhibitors in hypertension or heart failure?
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Drug Interactions; Drug Therapy, Combination; Hum

2001
[Diabetes and ischemic cardiopathy].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:9

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Coronary Disease; Diabetic Angiopathies; Hu

2001
Ophthalmology. What you can do to protect your eyes.
    Harvard health letter, 2001, Volume: 26, Issue:12

    Topics: Alcohol Drinking; Aspirin; Eye Injuries; Eye Protective Devices; Fibrinolytic Agents; Glaucoma; Huma

2001
Risk factors and primary prevention of ischemic heart disease in women.
    The Canadian journal of cardiology, 2001, Volume: 17 Suppl D

    Topics: Alcohol Drinking; Antioxidants; Aspirin; Diabetes Complications; Exercise; Female; Humans; Hyperlipi

2001
Hypertension in menopausal women--a special case, for special treatment?
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2001, Volume: 15, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female;

2001
Do acetylsalicylic acid and other antiplatelet drugs prevent preeclampsia?
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Aspirin; Autoimmune Diseases; Clinical Trials as Topic; Diabetes Complications; Dose-Response Relati

2001
C-reactive protein and cardiovascular disease: a review of risk prediction and interventions.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 317, Issue:1-2

    Topics: Age Factors; Arteriosclerosis; Aspirin; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Fe

2002
[Acetylsalicylic acid in primary prevention of cardiovascular events; literature study].
    Nederlands tijdschrift voor geneeskunde, 2002, Jan-12, Volume: 146, Issue:2

    Topics: Aged; Aged, 80 and over; Arteriosclerosis; Aspirin; Diabetes Mellitus; Humans; Hyperlipidemias; Hype

2002
Hypertensive diseases and eclampsia.
    Current opinion in obstetrics & gynecology, 2002, Volume: 14, Issue:2

    Topics: Antihypertensive Agents; Antioxidants; Aspirin; Eclampsia; Endothelial Growth Factors; Endothelium,

2002
[Aspirin-ACE inhibitors interaction: myth or reality?].
    Journal des maladies vasculaires, 2001, Volume: 26, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Coronary Disease; Drug Interactions; Humans; Hype

2001
Cardiovascular risk reduction in renal transplantation. Strategies for success.
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2002, Volume: 54, Issue:2

    Topics: Arteriosclerosis; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Comorbidity; Cost-Benefit

2002
Vascular reactivity to angiotensin II in human pregnancy.
    Seminars in perinatology, 1978, Volume: 2, Issue:1

    Topics: Adolescent; Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Volume; Dogs; Female; Haplorhini

1978
Physiopathology and pharmacotherapy of occlusive arterial disorders.
    Angiology, 1979, Volume: 30, Issue:7

    Topics: Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Platelets; Blood Viscosity; Cerebrovas

1979
Prostaglandins in circulatory disorders.
    Triangle; the Sandoz journal of medical science, 1979, Volume: 18, Issue:4

    Topics: Angiotensin II; Antihypertensive Agents; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platele

1979
The secondary prevention of myocardial infarction by drug treatment; excluding lipid lowering agents.
    Clinical and experimental hypertension. Part A, Theory and practice, 1992, Volume: 14, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Cardiovascular Agents; Humans; Hypert

1992
[Prostacyclin in hypertension].
    Zeitschrift fur Kardiologie, 1992, Volume: 81, Issue:6

    Topics: Aspirin; Epoprostenol; Humans; Hypertension; Vascular Resistance; Vasodilation

1992
The primary prevention of myocardial infarction.
    The New England journal of medicine, 1992, May-21, Volume: 326, Issue:21

    Topics: Alcohol Drinking; Aspirin; Blood Glucose; Cholesterol; Estrogen Replacement Therapy; Female; Humans;

1992
Blood pressure reduction and the prevention of stroke.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:7

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Blood Pressure; Cerebrovascular Disor

1991
[Is prevention of pre-eclampsia possible?].
    Zentralblatt fur Gynakologie, 1991, Volume: 113, Issue:15-16

    Topics: Antihypertensive Agents; Aspirin; Diuretics; Eclampsia; Female; Fetal Growth Retardation; Humans; Hy

1991
Recent developments in pregnancy-induced hypertension.
    Current opinion in obstetrics & gynecology, 1991, Volume: 3, Issue:6

    Topics: Anticonvulsants; Antihypertensive Agents; Aspirin; Diagnosis, Differential; Female; Humans; Hyperten

1991
A meta-analysis of low-dose aspirin for the prevention of pregnancy-induced hypertensive disease.
    JAMA, 1991, Jul-10, Volume: 266, Issue:2

    Topics: Aspirin; Cesarean Section; Clinical Trials as Topic; Female; Humans; Hypertension; Infant, Low Birth

1991
Low-dose aspirin to prevent pregnancy-induced hypertensive disease.
    JAMA, 1991, Dec-11, Volume: 266, Issue:22

    Topics: Aspirin; Female; Humans; Hypertension; Meta-Analysis as Topic; Pregnancy; Pregnancy Complications, C

1991
Diagnosis and management of chronic hypertension in pregnancy.
    Obstetrics and gynecology, 1991, Volume: 78, Issue:3 Pt 1

    Topics: Abruptio Placentae; Antihypertensive Agents; Aspirin; Blood Pressure Determination; Female; Humans;

1991
[Acetylsalicylic acid and pregnancy hypertension].
    Der Gynakologe, 1991, Volume: 24, Issue:4

    Topics: Aspirin; Epoprostenol; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complicatio

1991
Secondary prevention in elderly survivors of heart attacks.
    American family physician, 1988, Volume: 38, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aspirin; Cholesterol; Female; Humans; Hypertension; Male; Myocard

1988
[Primary prevention of intermittent claudication and frequently associated arteriopathies].
    Therapeutische Umschau. Revue therapeutique, 1987, Volume: 44, Issue:9

    Topics: Adult; Aspirin; Cerebrovascular Disorders; Coronary Disease; Diet; Humans; Hypercholesterolemia; Hyp

1987
The role of platelets in the development and complications of atherosclerosis.
    Seminars in hematology, 1986, Volume: 23, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Comple

1986
Lacunar infarcts.
    Clinical neurology and neurosurgery, 1986, Volume: 88, Issue:1

    Topics: Aspirin; Ataxia; Cerebral Angiography; Cerebral Infarction; Corpus Striatum; Electroencephalography;

1986
[Analogs of prostaglandin-related substances and inhibitors of their synthesis and metabolism. Clinical application: cardiovascular diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:3

    Topics: Angina Pectoris; Aspirin; Coronary Disease; Epoprostenol; Humans; Hypertension; Methacrylates; Myoca

1985
Prostaglandins in hematology.
    Archives of internal medicine, 1974, Volume: 133, Issue:1

    Topics: Animals; Aspirin; Blood Coagulation; Blood Platelets; Blood Preservation; Blood Transfusion; Chromiu

1974
The prostaglandins: their significance in clinical practice.
    Medical times, 1974, Volume: 102, Issue:12

    Topics: Abortion, Induced; Anemia, Hemolytic; Animals; Aspirin; Asthma; Chemical Phenomena; Chemistry; Cycli

1974

Trials

168 trials available for aspirin and Blood Pressure, High

ArticleYear
Long-Term Blood Pressure Variability and Kidney Function in Participants of the ASPREE Trial.
    American journal of hypertension, 2022, 02-01, Volume: 35, Issue:2

    Topics: Aged; Aspirin; Australia; Blood Pressure; Female; Glomerular Filtration Rate; Humans; Hypertension;

2022
Predictors of Atrial Fibrillation Development in Patients With Embolic Stroke of Undetermined Source: An Analysis of the RE-SPECT ESUS Trial.
    Circulation, 2021, 11-30, Volume: 144, Issue:22

    Topics: Administration, Oral; Age Factors; Aged; Aspirin; Atrial Fibrillation; Body Mass Index; Dabigatran;

2021
Effect of Hypertension on Efficacy and Safety of Ticagrelor-Aspirin Versus Clopidogrel-Aspirin in Minor Stroke or Transient Ischemic Attack.
    Stroke, 2022, Volume: 53, Issue:9

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Humans; Hypertension; Ischemic Attack, Transient; P

2022
Comparative antiplatelet effects of chlorthalidone and hydrochlorothiazide.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:10

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Dr

2022
The Efficacy of Rosuvastatin, Amlodipine, and Aspirin in the Treatment of Hypertension with Coronary Heart Disease and Its Effect on Platelet Aggregation.
    Disease markers, 2022, Volume: 2022

    Topics: Amlodipine; Antihypertensive Agents; Aspirin; Coronary Disease; Humans; Hypertension; Lipids; Platel

2022
Labetalol, Low-dose Aspirin, and Vitamin E and Calcium for Gestational Hypertension and Influence on MicroRNA-126 and PLGF Levels.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:4

    Topics: Aspirin; Calcium; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; MicroRNA

2023
Persisting risk factors for preeclampsia among high-risk pregnancies already using prophylactic aspirin: a multi-country retrospective investigation.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2023, Volume: 36, Issue:1

    Topics: Aspirin; Female; Folic Acid; Humans; Hypertension; Infant, Newborn; Obesity; Pre-Eclampsia; Pregnanc

2023
The impact of acetylsalicylic acid dosed at bedtime on circadian rhythms of blood pressure in the high-risk group of cardiovascular patients-a randomized, controlled trial.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:1

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Circadian Rhythm; Coronary Disease; Drug Adm

2021
Long-Term Blood Pressure Variability and Risk of Cardiovascular Disease Events Among Community-Dwelling Elderly.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Blood Pressure; Cardiovascular Di

2020
Association between aspirin use and cardiovascular outcomes in ALLHAT participants with and without chronic kidney disease: A post hoc analysis.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Humans; Hypertension; Myocardial Infarction; Renal Insufficiency,

2021
Preventive effect of aspirin on preeclampsia in high-risk pregnant women with stage 1 hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:5

    Topics: Aspirin; China; Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnant Wo

2021
Effect of L-arginine supplementation in pregnant women with chronic hypertension and previous placenta vascular disorders receiving Aspirin prophylaxis: a randomized control trial.
    Minerva obstetrics and gynecology, 2021, Volume: 73, Issue:6

    Topics: Arginine; Aspirin; Child; Dietary Supplements; Female; Humans; Hypertension; Infant; Infant, Newborn

2021
Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Dec-31, Volume: 66, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Blood Pressure; Do

2020
Favourable hypotensive effect after standardised tomato extract treatment in hypertensive subjects at high cardiovascular risk: a randomised controlled trial.
    Kardiologia polska, 2018, Volume: 76, Issue:2

    Topics: Adult; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Female;

2018
Preconception Blood Pressure Levels and Reproductive Outcomes in a Prospective Cohort of Women Attempting Pregnancy.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:5

    Topics: Abortion, Spontaneous; Adult; Aspirin; Blood Pressure; Blood Pressure Determination; Cohort Studies;

2018
Quality of Cardiovascular Disease Care in Small Urban Practices.
    Annals of family medicine, 2018, Volume: 16, Issue:Suppl 1

    Topics: Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Delivery of Health Care; Guideline Adhere

2018
Evaluation of the antihypertensive effect of nocturnal administration of acetylsalicylic acid: a cross-over randomized clinical trial.
    Journal of hypertension, 2019, Volume: 37, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascu

2019
Effects of policosanol in the functional recovery of non-cardioembolic ischemic stroke hypertensive patients.
    Revista de neurologia, 2018, Nov-01, Volume: 67, Issue:9

    Topics: Aged; Aspirin; Brain Ischemia; Double-Blind Method; Drug Therapy, Combination; Fatty Alcohols; Femal

2018
The effect of acetylsalicylic acid dosed at bedtime on the anti-aggregation effect in patients with coronary heart disease and arterial hypertension: A randomized, controlled trial.
    Cardiology journal, 2019, Volume: 26, Issue:6

    Topics: Aged; Arterial Pressure; Aspirin; Coronary Artery Disease; Drug Chronotherapy; Female; Humans; Hyper

2019
Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70).
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2019, Volume: 19, Issue:3

    Topics: Aged; Asian People; Aspirin; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus; Dyslipidem

2019
Assessing quality improvement capacity in primary care practices.
    BMC family practice, 2019, 07-25, Volume: 20, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Humans; Hypertension; Idaho; Oregon; Patient-Centered Care; Primar

2019
Zofenopril and ramipril and acetylsalicylic acid in postmyocardial infarction patients with left ventricular systolic dysfunction: a retrospective analysis in hypertensive patients of the SMILE-4 study.
    Journal of hypertension, 2013, Volume: 31, Issue:6

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Captopril; Europe; Female; Humans; Hypertens

2013
Protocol for assessing the hypotensive effect of evening administration of acetylsalicylic acid: study protocol for a randomized, cross-over controlled trial.
    Trials, 2013, Jul-27, Volume: 14

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian R

2013
A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk.
    European journal of preventive cardiology, 2015, Volume: 22, Issue:7

    Topics: Administration, Oral; Adrenergic beta-1 Receptor Antagonists; Aged; Angiotensin-Converting Enzyme In

2015
Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2014, Volume: 47, Issue:5

    Topics: Adult; Aspirin; Brazil; Calcium, Dietary; Chronic Disease; Double-Blind Method; Drug Combinations; F

2014
[The influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Atorvastatin; Blood Pressure; Blood Proteins; Drug Com

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
    JAMA, 2014, Dec-17, Volume: 312, Issue:23

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D

2014
A study about the relevance of adding acetylsalicylic acid in primary prevention in subjects with type 2 diabetes mellitus: effects on some new emerging biomarkers of cardiovascular risk.
    Cardiovascular diabetology, 2015, Jul-30, Volume: 14

    Topics: Aged; Amlodipine; Antihypertensive Agents; Aspirin; Biomarkers; Calcium Channel Blockers; Cardiovasc

2015
Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials.
    Ophthalmology, 2016, Volume: 123, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aspirin; Bevacizumab; Cardiovascul

2016
Achieved Blood Pressure and Outcomes in the Secondary Prevention of Small Subcortical Strokes Trial.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:1

    Topics: Aspirin; Blood Pressure; Blood Pressure Determination; Clopidogrel; Drug Therapy, Combination; Femal

2016
Rate of Gestational Diabetes Mellitus and Pregnancy Outcomes in Patients with Chronic Hypertension.
    American journal of perinatology, 2016, Volume: 33, Issue:8

    Topics: Adult; Aspirin; Diabetes, Gestational; Female; Gestational Age; Humans; Hypertension; Infant, Newbor

2016
Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2016, Volume: 66, Issue:646

    Topics: Arm; Aspirin; Blood Pressure; Blood Pressure Determination; Body Mass Index; Cross-Sectional Studies

2016
Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project.
    Stroke, 2016, Volume: 47, Issue:6

    Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Comorbidity; Diabetes Mellitus; Dyslipidemias; Fem

2016
Clinical study on influences of enteric coated aspirin on blood pressure and blood pressure variability.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:23

    Topics: Administration, Oral; Aspirin; Blood Pressure; Humans; Hypertension; Sleep

2016
Effect of regular oral intake of aspirin during pregnancy on pregnancy outcome of high-risk pregnancy-induced hypertension syndrome patients.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:23

    Topics: Aspirin; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pr

2016
The relationship between baseline blood pressure and computed tomography findings in acute stroke: data from the tinzaparin in acute ischaemic stroke trial (TAIST).
    Stroke, 2009, Volume: 40, Issue:1

    Topics: Acute Disease; Aspirin; Blood Pressure; Brain; Brain Ischemia; Causality; Cerebral Hemorrhage; Comor

2009
Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox".
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5

    Topics: Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Body Mass Index; Cell Adhesion Molecules

2009
The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study: baseline characteristics of the population.
    Cerebrovascular diseases (Basel, Switzerland), 2009, Volume: 27, Issue:6

    Topics: Activities of Daily Living; Aged; Aspirin; Cognition; Diabetes Complications; Dose-Response Relation

2009
Ambulatory blood pressure control with bedtime aspirin administration in subjects with prehypertension.
    American journal of hypertension, 2009, Volume: 22, Issue:8

    Topics: Adult; Aspirin; Blood Pressure; Circadian Rhythm; Double-Blind Method; Endpoint Determination; Femal

2009
Do proton pump inhibitors attenuate the effect of aspirin on platelet aggregation? A randomized crossover study.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Dis

2009
Candesartan improves maximal exercise capacity in hypertensives: results of a randomized placebo-controlled crossover trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:4

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Aspirin; Benzimidazol

2009
Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:5

    Topics: Aged; Aldosterone; Aspirin; Catecholamines; Circadian Rhythm; Cross-Over Studies; Dose-Response Rela

2009
Stroke and aspirin non-responder patients: relation with hypertension and platelet response to adenosine diphosphate.
    Platelets, 2009, Volume: 20, Issue:7

    Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Female; Humans; Hypertension; Male; Middle Ag

2009
Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events.
    American heart journal, 2010, Volume: 159, Issue:3

    Topics: Aged; Aged, 80 and over; Asian People; Aspirin; Cohort Studies; Diabetes Mellitus; Dose-Response Rel

2010
Sex differences in the administration-time-dependent effects of low-dose aspirin on ambulatory blood pressure in hypertensive subjects.
    Chronobiology international, 2010, Volume: 27, Issue:2

    Topics: Actigraphy; Adult; Aspirin; Blood Pressure; Drug Administration Schedule; Female; Humans; Hypertensi

2010
Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trial.
    Journal of the American College of Cardiology, 2010, Sep-14, Volume: 56, Issue:12

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Chronic Disease; Creatinine; Female; Glom

2010
Aspirin resistance in hypertensive patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:9

    Topics: Aged; Aspirin; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Platelet Aggregatio

2010
The effect of aspirin on C-reactive protein in hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Dose-Response Relationship, Dr

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
Erythrocyte fatty acid composition is associated with the risk of hypertension in middle-aged and older women.
    The Journal of nutrition, 2011, Volume: 141, Issue:9

    Topics: Aged; Aspirin; Blood Pressure; Case-Control Studies; Erythrocytes; Fatty Acids, Monounsaturated; Fat

2011
Is there a BP benefit of changing the time of aspirin administration in treated hypertensive patients?
    European journal of preventive cardiology, 2012, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Aspirin; Blood Pressure; Blo

2012
Correction of endothelial dysfunction in patients with arterial hypertension.
    Bulletin of experimental biology and medicine, 2011, Volume: 151, Issue:2

    Topics: Aspirin; Biomarkers; C-Reactive Protein; Celecoxib; Cyclooxygenase Inhibitors; Endothelium, Vascular

2011
Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score.
    Stroke, 2012, Volume: 43, Issue:6

    Topics: Age Factors; Aged; Aspirin; Body Weight; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; F

2012
Aspirin reduces cerebrovascular events in type 2 diabetic patients with poorly controlled blood pressure. Subanalysis from the JPAD trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:6

    Topics: Aged; Aspirin; Blood Pressure; Cardiovascular Agents; Cerebrovascular Disorders; Chi-Square Distribu

2012
Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2013, Volume: 22, Issue:6

    Topics: Aged; Antihypertensive Agents; Aspirin; Black or African American; Blood Pressure; Chi-Square Distri

2013
Comparison of risk factor reduction and tolerability of a full-dose polypill (with potassium) versus low-dose polypill (polycap) in individuals at high risk of cardiovascular diseases: the Second Indian Polycap Study (TIPS-2) investigators.
    Circulation. Cardiovascular quality and outcomes, 2012, Jul-01, Volume: 5, Issue:4

    Topics: Administration, Oral; Aged; Analysis of Variance; Antihypertensive Agents; Aspirin; Atenolol; Biomar

2012
The effect of enhanced depression care on adherence to risk-reducing behaviors after acute coronary syndromes: findings from the COPES trial.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Acute Coronary Syndrome; Antidepressive Agents; Aspirin; Depression; Diet; Exercise; Female; Humans;

2012
Effect of acetylsalicylic acid usage and platelet transfusion on postoperative hemorrhage and activities of daily living in patients with acute intracerebral hemorrhage.
    Journal of neurosurgery, 2013, Volume: 118, Issue:1

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Aspirin; Basal Ganglia; Craniotomy; Doub

2013
Randomized controlled trial of symptomatic middle cerebral artery stenosis: endovascular versus medical therapy in a Chinese population.
    Stroke, 2012, Volume: 43, Issue:12

    Topics: Adult; Aged; Angioplasty; Asian People; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combi

2012
Assessment of the Siksika chronic disease nephropathy-prevention clinic.
    Canadian family physician Medecin de famille canadien, 2013, Volume: 59, Issue:1

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bl

2013
The evening versus morning polypill utilization study: the TEMPUS rationale and design.
    European journal of preventive cardiology, 2014, Volume: 21, Issue:4

    Topics: Administration, Oral; Antihypertensive Agents; Aspirin; Biomarkers; Blood Platelets; Blood Pressure;

2014
[Dilzem-retard efficiency in patients with ischemic heart disease and heart failure].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Channel Blockers; Delayed-Action Pre

2002
[The effect of aspirin on rheological properties of erythrocytes in essential hypertension].
    Przeglad lekarski, 2002, Volume: 59, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non

2002
Effect of diaspirin crosslinked hemoglobin (DCLHb HemAssist) during high blood loss surgery on selected indices of organ function.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2002, Volume: 30, Issue:4

    Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Substitutes; Digestive System; Digestive System Surgical

2002
Benefit and harm of low-dose aspirin in well-treated hypertensives at different baseline cardiovascular risk.
    Journal of hypertension, 2002, Volume: 20, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Humans; Hypertension; Myocardial I

2002
Health economics in the Hypertension Optimal Treatment (HOT) study: costs and cost-effectiveness of intensive blood pressure lowering and low-dose aspirin in patients with hypertension.
    Journal of internal medicine, 2003, Volume: 253, Issue:4

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analy

2003
Administration time-dependent effects of aspirin on blood pressure in untreated hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Blood Pressure Monito

2003
9 alpha,11 beta-prostaglandin F2 in pregnancies at high risk for hypertensive disorders of pregnancy, and the effect of acetylsalicylic acid.
    Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 69, Issue:1

    Topics: Aspirin; Dinoprost; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications,

2003
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase I

2003
Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial.
    Annals of internal medicine, 2003, Oct-07, Volume: 139, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors

2003
[High doses of aspirin reduce natriuresis in hypertensive patients treated with enalapril].
    Medicina, 2004, Volume: 64, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Cross-Over Studies; Double-Blind Method; Enalapril; F

2004
Cyclooxygenase-2 specific inhibitors and upper gastrointestinal tolerability in patients with osteoarthritis receiving concomitant low dose aspirin: pooled analysis of 2 trials.
    The Journal of rheumatology, 2005, Volume: 32, Issue:1

    Topics: Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method

2005
Factors associated with development of stroke long-term after myocardial infarction: experiences from the LoWASA trial.
    Journal of internal medicine, 2005, Volume: 257, Issue:2

    Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Female; Follow-

2005
Effects of low-dose aspirin on blood pressure and endothelial function of treated hypertensive hypercholesterolaemic subjects.
    Journal of human hypertension, 2005, Volume: 19, Issue:9

    Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brac

2005
Differing administration time-dependent effects of aspirin on blood pressure in dipper and non-dipper hypertensives.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Adult; Antioxidants; Aspirin; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response R

2005
The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study.
    Journal of the American College of Cardiology, 2005, Sep-06, Volume: 46, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Atenolol; Drug

2005
Aspirin administered at bedtime, but not on awakening, has an effect on ambulatory blood pressure in hypertensive patients.
    Journal of the American College of Cardiology, 2005, Sep-20, Volume: 46, Issue:6

    Topics: Adult; Aged; Aspirin; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hyper

2005
Prevalence and management of hypertension in acute coronary syndrome patients varies by sex: observations from the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes (SYMPHONY) randomized clinical
    American heart journal, 2005, Volume: 150, Issue:6

    Topics: Acute Disease; Aged; Angina, Unstable; Aspirin; Chemistry, Pharmaceutical; Coronary Disease; Female;

2005
A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial.
    International journal of cardiology, 2007, Apr-25, Volume: 117, Issue:2

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Bloo

2007
[Disturbances in aggregability of red blood cells in essential hypertension].
    Folia medica Cracoviensia, 2005, Volume: 46, Issue:1-2

    Topics: Adult; Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Dose-Response Relationship, Drug;

2005
Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting.
    Clinical drug investigation, 2007, Volume: 27, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Asp

2007
Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease.
    Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:1

    Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Colla

2009
Influence of indometacin and acetylsalicylic acid on the therapeutic effectiveness of talinolol in patients with essential hypertension.
    Biomedica biochimica acta, 1984, Volume: 43, Issue:8-9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Blood Pressure; Clinical Trials as Topic; Drug Th

1984
Effects of indomethacin, sulindac, naproxen, aspirin, and paracetamol in treated hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:6

    Topics: Acetaminophen; Aldosterone; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method;

1984
Non-steroidal anti-inflammatory drugs and blood pressure.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Pressure; Blood Pressure Determina

1982
Aspirin in coronary heart disease. The Coronary Drug Project Research Group.
    Circulation, 1980, Volume: 62, Issue:6 Pt 2

    Topics: Aspirin; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Hematuria; Humans; Hyperte

1980
Does chronic aspirin treatment increase blood pressure in man?
    Klinische Wochenschrift, 1981, Mar-16, Volume: 59, Issue:6

    Topics: Aspirin; Blood Pressure; Humans; Hypertension; Myocardial Infarction; Platelet Aggregation

1981
The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results.
    Blood pressure, 1994, Volume: 3, Issue:5

    Topics: Adrenergic beta-Antagonists; Age Distribution; Aged; Aged, 80 and over; Angiotensin-Converting Enzym

1994
A study of use of low dose aspirin in prevention of pregnancy induced hypertension.
    Journal of the Indian Medical Association, 1994, Volume: 92, Issue:6

    Topics: Aspirin; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy

1994
Uterine Doppler in the identification of patients at risk for hypertension and IUGR.
    Journal of perinatal medicine, 1994, Volume: 22 Suppl 1

    Topics: Aspirin; Double-Blind Method; Female; Fetal Growth Retardation; Humans; Hypertension; Infant, Newbor

1994
Effects of dihydropyridines and their combination with aspirin on blood pressure and circadian platelet activity in patients with essential hypertension.
    American journal of hypertension, 1994, Volume: 7, Issue:7 Pt 2

    Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Circadian Rhythm; Dihydropyridines; Double-Blind Me

1994
Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients.
    Blood pressure, 1994, Volume: 3, Issue:4

    Topics: Adult; Aldosterone; Aspirin; Captopril; Cross-Over Studies; Double-Blind Method; Female; Hemodynamic

1994
A prospective study of plasma homocyst(e)ine and risk of ischemic stroke.
    Stroke, 1994, Volume: 25, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Brain Ischemi

1994
Low-dose aspirin and hypertension in pregnancy.
    Lancet (London, England), 1993, Jan-30, Volume: 341, Issue:8840

    Topics: Aspirin; Double-Blind Method; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Card

1993
Prevention of pregnancy-induced hypertension in twins by early administration of low-dose aspirin: a preliminary report.
    American journal of reproductive immunology (New York, N.Y. : 1989), 1994, Volume: 31, Issue:1

    Topics: Adult; Aspirin; Double-Blind Method; Embryonic and Fetal Development; Female; Humans; Hypertension;

1994
Neonatal platelet reactivity and serum thromboxane B2 production in whole blood: the effect of maternal low dose aspirin.
    British journal of obstetrics and gynaecology, 1994, Volume: 101, Issue:3

    Topics: Adult; Aspirin; Double-Blind Method; Female; Fetal Blood; Humans; Hypertension; In Vitro Techniques;

1994
Treatment of hypertension with dihydropyridine calcium antagonists and aspirin.
    Blood pressure. Supplement, 1994, Volume: 1

    Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dihydro

1994
Low dose aspirin in hypertensive pregnant women: effect on pregnancy outcome and prostacyclin-thromboxane balance in mother and newborn.
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:9

    Topics: Adult; Aspirin; Drug Administration Schedule; Epoprostenol; Female; Humans; Hypertension; Pre-Eclamp

1993
Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 4, Issue:5

    Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Captopril; Double-Blind Method; Drug Interactions;

1993
[Acetylsalicylic acid and kurantil in the prevention of pregnancy complications in glomerulonephritis and hypertension].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:6

    Topics: Abortion, Spontaneous; Analysis of Variance; Aspirin; Chronic Disease; Dipyridamole; Drug Therapy, C

1993
Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
    The New England journal of medicine, 1993, Oct-21, Volume: 329, Issue:17

    Topics: Abruptio Placentae; Adult; Aspirin; Double-Blind Method; Female; Humans; Hypertension; Incidence; Pa

1993
Treatment of hypertension with calcium antagonists and aspirin. Effects on 24-h platelet activity.
    American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2

    Topics: Adult; Aspirin; Circadian Rhythm; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hy

1993
Low-dose aspirin therapy to prevent preeclampsia.
    American journal of obstetrics and gynecology, 1993, Volume: 168, Issue:4

    Topics: Adult; Aspirin; Eclampsia; Female; Humans; Hypertension; Parity; Pre-Eclampsia; Pregnancy; Pregnancy

1993
Blood pressure and risk of stroke in patients with cerebrovascular disease. The United Kingdom Transient Ischaemic Attack Collaborative Group.
    BMJ (Clinical research ed.), 1996, Jul-20, Volume: 313, Issue:7050

    Topics: Aspirin; Cerebrovascular Disorders; Diastole; Female; Humans; Hypertension; Male; Middle Aged; Recur

1996
Risk factors for pregnancy-induced hypertension in women at high risk for the condition. Italian Study of Aspirin in Pregnancy Group.
    Epidemiology (Cambridge, Mass.), 1996, Volume: 7, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index; Educational Status; Female

1996
Platelet angiotensin II receptor status during pregnancy in Chinese women at high-risk of developing pregnancy-induced hypertension.
    Gynecologic and obstetric investigation, 1996, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Angiotensin II; Aspirin; Blood Platelets; Calcium; Cohort Studies; Female; Food,

1996
Neonatal outcome in a randomized, controlled trial of low-dose aspirin in high-risk pregnancies.
    Journal of paediatrics and child health, 1995, Volume: 31, Issue:6

    Topics: Aspirin; Chronic Disease; Double-Blind Method; Female; Humans; Hypertension; Infant, Newborn; Kidney

1995
An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. ACAS Investigators. Asymptomatic Carotid Atherosclerosis Study.
    Stroke, 1996, Volume: 27, Issue:12

    Topics: Anesthesia; Arteriosclerosis; Aspirin; Carotid Stenosis; Cerebral Infarction; Combined Modality Ther

1996
Hypertension and borderline isolated systolic hypertension increase risks of cardiovascular disease and mortality in male physicians.
    Circulation, 1997, Mar-04, Volume: 95, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Aspirin; beta Carotene; Cardiovascular Diseases; Cereb

1997
Improvement of alveolar-capillary membrane diffusing capacity with enalapril in chronic heart failure and counteracting effect of aspirin.
    Circulation, 1997, Apr-01, Volume: 95, Issue:7

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood-Air Barrier; Bradykinin; Cyclooxygena

1997
Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease.
    Circulation, 1997, Jul-01, Volume: 96, Issue:1

    Topics: Adult; Aged; Aspirin; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies;

1997
[The antagonistic effect of aspirin on the expression of prostaglandin participation in the antihypertensive activity of ACE inhibitors].
    Cardiologia (Rome, Italy), 1997, Volume: 42, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Drug Interactions; Enala

1997
Role of low dose aspirin in prevention of pregnancy induced hypertension.
    Journal of the Indian Medical Association, 1997, Volume: 95, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Admi

1997
Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia.
    Lancet (London, England), 1997, Nov-01, Volume: 350, Issue:9087

    Topics: Adult; Antihypertensive Agents; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Hum

1997
The Hypertension Optimal Treatment (HOT) Study: 24-month data on blood pressure and tolerability.
    Blood pressure, 1997, Volume: 6, Issue:5

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Dis

1997
Influence of aspirin usage on blood pressure: dose and administration-time dependencies.
    Chronobiology international, 1997, Volume: 14, Issue:6

    Topics: Adult; Aspirin; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Met

1997
[Long-term clinical tolerance of antihypertensive treatment during the HOT study. Groupe français de l'etude HOT].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:8

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases;

1997
[The Hypertension Optimal Treatment (HOT) study: results of 12-month therapy related to age].
    Deutsche medizinische Wochenschrift (1946), 1998, Jan-02, Volume: 123, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inh

1998
Low-dose aspirin to prevent preeclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
    The New England journal of medicine, 1998, Mar-12, Volume: 338, Issue:11

    Topics: Adult; Aspirin; Chronic Disease; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; Hyp

1998
Effects of aspirin on angiotensin-converting enzyme inhibition and left ventricular dilation one year after acute myocardial infarction.
    The American journal of cardiology, 1998, May-15, Volume: 81, Issue:10

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Female; Humans; Hydroxybutyrate

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin;

1998
Efficacy of antiplatelet treatment in hypertensive patients with TIA or stroke.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:2

    Topics: Aspirin; Blood Pressure; Cerebrovascular Disorders; Dipyridamole; Double-Blind Method; Drug Therapy,

1998
[Influence of some parameters on the blood pressure reduction under treatment: experience from the Hypertension Optimal Treatment Study].
    Archives des maladies du coeur et des vaisseaux, 1998, Volume: 91, Issue:8

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases; Diastole; Drug Ther

1998
The HOT Study. Hypertension Optimal Therapy.
    Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:2

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Cerebrovascular

1998
Predictors of pre-eclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
    American journal of obstetrics and gynecology, 1998, Volume: 179, Issue:4

    Topics: Adult; Aspirin; Blood Pressure; Female; Gestational Age; Humans; Hypertension; Parity; Placebos; Pre

1998
[How far should arterial pressure in hypertension be lowered?].
    Presse medicale (Paris, France : 1983), 1998, Nov-07, Volume: 27, Issue:34

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Double-Blind Method; Fema

1998
[Recommended article of the month: Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1998, Volume: 17, Issue:10

    Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Cerebrovascular Disorders; Female; Humans; Hypertensi

1998
Do intensive blood pressure lowering and low-dose ASA help our hypertensive patients?
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti

1998
Secondary prevention in coronary heart disease: a randomised trial of nurse led clinics in primary care.
    Heart (British Cardiac Society), 1998, Volume: 80, Issue:5

    Topics: Aged; Ambulatory Care Facilities; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease

1998
Aggressive blood pressure lowering is safe, but benefit is still hard to prove.
    Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti

1999
In the dose range of 0.5-2.0 mg/kg, acetylsalicylic acid does not affect prostacyclin production in hypertensive pregnancies.
    Acta obstetricia et gynecologica Scandinavica, 1999, Volume: 78, Issue:2

    Topics: Aspirin; Epoprostenol; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pregnancy; Pre

1999
Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators.
    Circulation, 1999, May-11, Volume: 99, Issue:18

    Topics: Acute Disease; Age Factors; Aged; Angina, Unstable; Aspirin; Brain Damage, Chronic; Cerebral Hemorrh

1999
The Hypertension Optimal Treatment study and the importance of lowering blood pressure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1999, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti

1999
[Repercussions in clinical practice of the results of the HOT (Hypertension Optimal Treatment) study].
    Revista espanola de cardiologia, 1999, Volume: 52, Issue:6

    Topics: Aged; Aspirin; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged;

1999
[Lowering of diastolic blood pressure < or = 90 mmHg should not be attempted, except in type 2 diabetics; the 'Hypertension optimal treatment' (HOT) trial].
    Nederlands tijdschrift voor geneeskunde, 1999, Jun-05, Volume: 143, Issue:23

    Topics: Adult; Aged; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Me

1999
Compliance with aspirin or placebo in the Hypertension Optimal Treatment (HOT) study.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Female; Fibrinolytic Agents; Humans; Hyperte

1999
Calcium and low-dose aspirin prophylaxis in women at high risk of pregnancy-induced hypertension.
    Hypertension in pregnancy, 1999, Volume: 18, Issue:2

    Topics: Analysis of Variance; Aspirin; Calcium; Chi-Square Distribution; Dietary Supplements; Female; Humans

1999
Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan.
    American journal of hypertension, 1999, Volume: 12, Issue:8 Pt 1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; C

1999
[Effect of intensive antihypertensive treatment and of aspirin in a low dose in the hypertensive. The HOT (Hypertension Optimal Treatment) study].
    Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:8

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Dose-Response Relationship, Drug; Double-

1999
Risks of preeclampsia and adverse neonatal outcomes among women with pregestational diabetes mellitus. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
    American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:2

    Topics: Aspirin; Birth Weight; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female;

2000
Principal results of hypertension optimal treatment (HOT) study and their clinical impact. HOT cooperative group.
    Clinical hemorheology and microcirculation, 1999, Volume: 21, Issue:3-4

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Pressure; Cardiovascular Physiological Phenomena; Humans; Hy

1999
Influence of gender and age on preventing cardiovascular disease by antihypertensive treatment and acetylsalicylic acid. The HOT study. Hypertension Optimal Treatment.
    Journal of hypertension, 2000, Volume: 18, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascul

2000
Effects of low-dose aspirin on clinic and ambulatory blood pressure in treated hypertensive patients. Collaborative Group of the Primary Prevention Project (PPP)--Hypertension study.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Blood

2000
Alcohol consumption and risk of coronary heart disease by diabetes status.
    Circulation, 2000, Aug-01, Volume: 102, Issue:5

    Topics: Alcohol Drinking; Aspirin; beta Carotene; Cardiovascular Diseases; Coronary Disease; Diabetes Mellit

2000
Different patterns of renal prostaglandins I2 and E2 in patients with essential hypertension with low to normal or high renin activity.
    Journal of hypertension, 2000, Volume: 18, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Dinoprostone; Epoprostenol; Female; Humans; Hypertensi

2000
Renal function and intensive lowering of blood pressure in hypertensive participants of the hypertension optimal treatment (HOT) study.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:2

    Topics: Aged; Aspirin; Blood Pressure; Creatinine; Female; Humans; Hypertension; Kidney; Male; Middle Aged

2001
Does antiplatelet therapy prevent preeclampsia and its complications?
    The Journal of family practice, 2001, Volume: 50, Issue:5

    Topics: Aspirin; Female; Guidelines as Topic; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Ecl

2001
Twenty-four hour ambulatory blood pressure in the Hypertension Optimal Treatment (HOT) study.
    Journal of hypertension, 2001, Volume: 19, Issue:10

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Blood Pressure Determinat

2001
[Antihypertensive effect of enalapril and lisinopril administered in combination with nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:9

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihyperte

2001
Role of cyclooxygenase products in the regulation of vascular tone and in the endothelial vasodilator function of normal, hypertensive, and hypercholesterolemic humans.
    The American journal of cardiology, 2002, Feb-01, Volume: 89, Issue:3

    Topics: Acetylcholine; Aspirin; Blood Flow Velocity; Brachial Artery; Cholesterol; Cholesterol, HDL; Cholest

2002
Low dose acetylsalicylic acid in prevention of pregnancy-induced hypertension and intrauterine growth retardation in women with bilateral uterine artery notches.
    BJOG : an international journal of obstetrics and gynaecology, 2002, Volume: 109, Issue:2

    Topics: Adult; Arteries; Aspirin; Birth Weight; Blood Flow Velocity; Double-Blind Method; Female; Fetal Grow

2002
Blood pressure and clinical outcomes in the International Stroke Trial.
    Stroke, 2002, Volume: 33, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Pressure; Brain Ischemia; Cohort Studies; Fe

2002
Low-dose aspirin does not interfere with the blood pressure-lowering effects of antihypertensive therapy.
    Journal of hypertension, 2002, Volume: 20, Issue:5

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases; Cardiovascular Syst

2002
Failure of aspirin to antagonize the antihypertensive effect of spironolactone in low-renin hypertension.
    Southern medical journal, 1976, Volume: 69, Issue:8

    Topics: Adult; Aspirin; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Drug Interactions; Fe

1976
[Low-dose aspirin in prevention and therapy of hypertension in pregnancy].
    Gynakologisch-geburtshilfliche Rundschau, 1992, Volume: 32 Suppl 1

    Topics: Aspirin; Austria; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertensio

1992
Low-dose aspirin in primigravidae with positive roll-over test.
    Gynecologic and obstetric investigation, 1992, Volume: 34, Issue:3

    Topics: Aspirin; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Infant, Newborn; Male; P

1992
[The Hypertension Optimal Treatment Study. Background information].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:20

    Topics: Aged; Aged, 80 and over; Aspirin; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female

1992
Differences in the outcome of patients with TIA versus minor stroke.
    Acta neurologica Scandinavica, 1992, Volume: 85, Issue:3

    Topics: Adolescent; Adult; Aged; Anticoagulants; Aspirin; Cause of Death; Cerebral Infarction; Dose-Response

1992
Hypertension in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Mar-23, Volume: 44, Issue:1

    Topics: Angiotensin II; Aspirin; Blood Flow Velocity; Female; Fetus; Humans; Hypertension; Placenta; Pre-Ecl

1992
A randomized placebo-controlled study of the effect of low dose aspirin on platelet reactivity and serum thromboxane B2 production in non-pregnant women, in normal pregnancy, and in gestational hypertension.
    British journal of obstetrics and gynaecology, 1992, Volume: 99, Issue:5

    Topics: Adult; Arachidonic Acid; Aspirin; Collagen; Female; Humans; Hypertension; Platelet Aggregation; Plat

1992
Doppler ultrasound and aspirin in recognition and prevention of pregnancy-induced hypertension.
    Lancet (London, England), 1990, Jun-30, Volume: 335, Issue:8705

    Topics: Administration, Oral; Adult; Aspirin; Blood Platelets; Drug Administration Schedule; Drug Evaluation

1990
Low-dose aspirin does not influence the clinical course of women with mild pregnancy-induced hypertension.
    Obstetrics and gynecology, 1990, Volume: 76, Issue:5 Pt 1

    Topics: Adult; Aspirin; Double-Blind Method; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnan

1990
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Chromatography, Affin

1990
The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies.
    The New England journal of medicine, 1989, Aug-10, Volume: 321, Issue:6

    Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Epoprostenol; Female; Humans; Hyperte

1989
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.
    The New England journal of medicine, 1989, Aug-10, Volume: 321, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Fetus; Humans;

1989
Prevention of coronary heart disease in practice. Implications of the results of recent clinical trials.
    JAMA, 1985, Jul-12, Volume: 254, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina, Unstable; Aspirin; Blood Platelets; Cholesterol; C

1985
Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.
    Lancet (London, England), 1986, Jan-04, Volume: 1, Issue:8471

    Topics: Adolescent; Adult; Angiotensin II; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind M

1986
Controlled trial of aspirin in cerebral ischemia: an addendum.
    Neurology, 1986, Volume: 36, Issue:5

    Topics: Aspirin; Blindness; Carotid Artery Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Di

1986

Other Studies

466 other studies available for aspirin and Blood Pressure, High

ArticleYear
Aspirin does not affect hematoma growth in severe spontaneous intracranial hematoma.
    Neurosurgical review, 2022, Volume: 45, Issue:2

    Topics: Aspirin; Cerebral Hemorrhage; Hematoma; Humans; Hypertension; Retrospective Studies

2022
Antihypertensive treatments and risks of lung Cancer: a large population-based cohort study in Hong Kong.
    BMC cancer, 2021, Nov-11, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Female; Fol

2021
Aspirin Use for Preeclampsia Prevention Among Women With Prepregnancy Diabetes, Obesity, and Hypertension.
    JAMA, 2022, 01-25, Volume: 327, Issue:4

    Topics: Adolescent; Adult; Aspirin; Female; Humans; Hypertension; Length of Stay; Obesity; Pre-Eclampsia; Pr

2022
Managing Hypertension, Diabetes, and Cardiovascular Disease Risk via Short-Term Medical Trips: A Retrospective Longitudinal Study in Santo Domingo.
    Annals of global health, 2022, Volume: 88, Issue:1

    Topics: Aspirin; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Hu

2022
Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study.
    The American journal of gastroenterology, 2022, 05-01, Volume: 117, Issue:5

    Topics: Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Female; Hepatitis B virus; Hepatitis B, Chronic;

2022
Evaluation of the association between admission systolic blood pressure and the choice of initial antiplatelet therapy for minor ischemic stroke in real-world.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:4

    Topics: Aged; Aspirin; Blood Pressure; Clopidogrel; Drug Therapy, Combination; Humans; Hypertension; Ischemi

2022
Analysis of Aspirin Use and Cardiovascular Events and Mortality Among Adults With Hypertension and Controlled Systolic Blood Pressure.
    JAMA network open, 2022, 04-01, Volume: 5, Issue:4

    Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure; Humans; Hypertension

2022
An Evaluation of Aspirin Treatment Preferences ORIGINAL INVESTIGATION of Physicians in Hypertensive Patients in Terms of Current Guidelines: A Subgroup Analysis of the ASSOS Trial in Turkey.
    Anatolian journal of cardiology, 2022, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aspirin; Cross-Sectional Studies; Humans; Hypertension; Physicians; Turkey

2022
Validation of the EDAN SA-10 ambulatory blood pressure monitor in general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Universal Stan
    Blood pressure monitoring, 2022, Aug-01, Volume: 27, Issue:4

    Topics: Aspirin; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Blood

2022
Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage.
    Clinical science (London, England : 1979), 2022, 05-13, Volume: 136, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Endothelin-1; Epopros

2022
Risk factor management matters more than pharmaceutical cyclooxygenase-2 inhibition in the prevention of de novo intracranial aneurysms.
    European journal of neurology, 2022, Volume: 29, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Din

2022
Low-dose aspirin use and colorectal cancer survival in 32,195 patients-A national cohort study.
    Cancer medicine, 2023, Volume: 12, Issue:1

    Topics: Aspirin; Cohort Studies; Colorectal Neoplasms; Digestive System Surgical Procedures; Humans; Hyperte

2023
Efficacy of discontinuing the use of low-dose aspirin at 28 weeks of gestation for preventing preeclampsia.
    The journal of obstetrics and gynaecology research, 2022, Volume: 48, Issue:11

    Topics: Aspirin; Female; Fetal Growth Retardation; Humans; Hypertension; Infant, Newborn; Postpartum Hemorrh

2022
Low-dose Aspirin may Prevent Preeclampsia by Inhibiting the Expression of ATF2.
    Endocrine, metabolic & immune disorders drug targets, 2023, Volume: 23, Issue:5

    Topics: Activating Transcription Factor 2; Aspirin; Female; Humans; Hypertension; Interleukin-6; Interleukin

2023
Risk factors for in-stent restenosis after coronary stent implantation in patients with coronary artery disease: A retrospective observational study.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Aspirin; Constriction, Pathologic; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus,

2022
Risk factors for in-stent restenosis after coronary stent implantation in patients with coronary artery disease: A retrospective observational study.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Aspirin; Constriction, Pathologic; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus,

2022
Risk factors for in-stent restenosis after coronary stent implantation in patients with coronary artery disease: A retrospective observational study.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Aspirin; Constriction, Pathologic; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus,

2022
Risk factors for in-stent restenosis after coronary stent implantation in patients with coronary artery disease: A retrospective observational study.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Aspirin; Constriction, Pathologic; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus,

2022
Reply: Low dose aspirin prophylaxis in pregnant women with chronic hypertension: more questions than answers.
    American journal of obstetrics and gynecology, 2023, Volume: 228, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pr

2023
Low-dose aspirin prophylaxis in pregnant women with chronic hypertension: more questions than answers.
    American journal of obstetrics and gynecology, 2023, Volume: 228, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pr

2023
Aspirin in diabetic patients at primary prevention: insights of the VITAL cohort.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:7

    Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Hypertension; Male; Retrospective Studi

2023
Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats.
    Molecules (Basel, Switzerland), 2023, Feb-15, Volume: 28, Issue:4

    Topics: Animals; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Collagen; Hypertension; Int

2023
Preventive effect of Helicobacter pylori eradication on the coronary heart diseases depending on age and sex with a median follow-up of 51 months.
    Helicobacter, 2023, Volume: 28, Issue:4

    Topics: Anti-Bacterial Agents; Aspirin; Coronary Disease; Female; Follow-Up Studies; Helicobacter Infections

2023
Understanding the dosing-time-dependent antihypertensive effect of valsartan and aspirin through mathematical modeling.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Antihypertensive Agents; Aspirin; Humans; Hypertension; Tetrazoles; Valine; Valsartan

2023
Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy.
    Clinical neurology and neurosurgery, 2023, Volume: 231

    Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; H

2023
Influence of Socioeconomic Gender Inequality on Sex Disparities in Prevention and Outcome of Cardiovascular Disease: Data From a Nationwide Population Cohort in China.
    Journal of the American Heart Association, 2023, 10-17, Volume: 12, Issue:20

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular

2023
Missed opportunities in aspirin prescribing for preeclampsia prevention.
    BMC pregnancy and childbirth, 2023, Oct-07, Volume: 23, Issue:1

    Topics: Aspirin; Female; Humans; Hypertension; Maternal Mortality; Morbidity; Pre-Eclampsia; Pregnancy; Retr

2023
Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study.
    World journal of urology, 2023, Volume: 41, Issue:12

    Topics: Adult; Aged; Aspirin; Cross-Sectional Studies; Diabetes Mellitus; Humans; Hypertension; Kidney Calcu

2023
Aspirin Use and the Risk of Mortality in Patients With Hypertension.
    American family physician, 2023, Volume: 108, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hypertension

2023
Nutricional intake, maternal outcomes and knowledge on preeclampsia prevention: Was there impact during the COVID-19 pandemic among women with hypertension?
    Pregnancy hypertension, 2023, Volume: 34

    Topics: Adult; Aspirin; Calcium; COVID-19; Female; Humans; Hypertension; Pandemics; Pre-Eclampsia; Pregnancy

2023
Aspirin in primary prevention: 'nothing else matters' … like hypertension.
    Journal of hypertension, 2019, Volume: 37, Issue:11

    Topics: Aged; Aspirin; Atherosclerosis; Blood Pressure; Blood Pressure Determination; Humans; Hypertension

2019
The Impact of the New Hypertension Guidelines to Low-Dose Aspirin Prophylaxis Eligibility for the Prevention of Preeclampsia: A Cost-Benefit Analysis.
    American journal of perinatology, 2021, Volume: 38, Issue:4

    Topics: American Heart Association; Aspirin; Blood Pressure; Cost-Benefit Analysis; Eligibility Determinatio

2021
Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea.
    Drugs & aging, 2020, Volume: 37, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2

2020
Low-Dose Aspirin Treatment Attenuates Male Rat Salt-Sensitive Hypertension via Platelet Cyclooxygenase 1 and Complement Cascade Pathway.
    Journal of the American Heart Association, 2020, 01-07, Volume: 9, Issue:1

    Topics: Animals; Aspirin; Blood Platelets; Blood Pressure; Cells, Cultured; Complement Activation; Cyclooxyg

2020
Impact of the ACOG guideline regarding low-dose aspirin for prevention of superimposed preeclampsia in women with chronic hypertension.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:3

    Topics: Adult; Aspirin; Cohort Studies; Female; Humans; Hypertension; Incidence; Philadelphia; Platelet Aggr

2020
[2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases: what's new? The diabetologist's point of view].
    Giornale italiano di cardiologia (2006), 2020, Volume: 21, Issue:4

    Topics: Anticoagulants; Aspirin; Cardiology; Cholesterol, LDL; Diabetic Cardiomyopathies; Europe; Heart Dise

2020
Baseline clinical characteristics and patient profile of the TURKMI registry: Results of a nation-wide acute myocardial infarction registry in Turkey.
    Anatolian journal of cardiology, 2020, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin Receptor Antagonists; Angiotensin-Conver

2020
Potential drug-drug interactions in ICU patients: a retrospective study.
    Drug metabolism and personalized therapy, 2020, 07-20, Volume: 35, Issue:3

    Topics: Aspirin; Diabetes Mellitus; Drug Interactions; Enoxaparin; Hospitalization; Humans; Hypertension; In

2020
Atypical Spontaneous Hematomas in a Patient with Severe Coronavirus Disease 2019 (COVID-19).
    Seminars in thrombosis and hemostasis, 2020, Volume: 46, Issue:7

    Topics: Aged, 80 and over; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Erythrocyte Transfusi

2020
Clinical factors associated with safety and efficacy in patients receiving direct oral anticoagulants for non-valvular atrial fibrillation.
    Scientific reports, 2020, 11-19, Volume: 10, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulan

2020
81-mg aspirin: a dosing dilemma.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy

2021
81 mg aspirin: a dosing dilemma response.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy

2021
Impact of aspirin on preeclampsia response.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:5

    Topics: Aspirin; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Ri

2021
Impact of aspirin on preeclampsia.
    American journal of obstetrics and gynecology, 2021, Volume: 224, Issue:5

    Topics: Aspirin; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Ri

2021
Aspirin Use and Misuse for the Primary Prevention of Cardiovascular Diseases.
    American journal of preventive medicine, 2021, Volume: 60, Issue:4

    Topics: Adult; Aspirin; Cardiovascular Diseases; Female; Humans; Hypertension; Male; Primary Prevention; Ris

2021
The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection.
    The FEBS journal, 2021, Volume: 288, Issue:17

    Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; COVID-19; COVID-19 Drug Treatment; Diabetes Mellitus;

2021
Risk factors among stroke subtypes and its impact on the clinical outcome of patients of Northern Portugal under previous aspirin therapy.
    Clinical neurology and neurosurgery, 2021, Volume: 203

    Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Cohort Studies; Dyslipidemias; F

2021
Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials.
    Journal of hypertension, 2021, 08-01, Volume: 39, Issue:8

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Drug Combinations; Humans; Hydroxymethylglutaryl-C

2021
Decreased in-hospital mortality associated with aspirin administration in hospitalized patients due to severe COVID-19.
    Journal of medical virology, 2021, Volume: 93, Issue:9

    Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Antiviral Agents; Aspirin; Blood Platelets; Coronary

2021
Long-term continuous use of proton-pump inhibitors is associated with renal function decline in patients without acute kidney injury.
    Clinical and experimental nephrology, 2021, Volume: 25, Issue:10

    Topics: Acute Kidney Injury; Aged; Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal

2021
Associastion of In-hospital Use of Statins, Aspirin, and Renin-Angiotensin-Aldosterone Inhibitors with Mortality and ICU Admission Due to COVID-19.
    Advances in experimental medicine and biology, 2021, Volume: 1327

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensin

2021
Restless legs syndrome/Willis-Ekbom disease in type 2 diabetes as the initial manifestation of Parkinson's disease and major cardiovascular disease.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017, Volume: 17, Issue:6

    Topics: Aged; Amines; Analgesics; Anticonvulsants; Antihypertensive Agents; Antiparkinson Agents; Aspirin; B

2017
Health Benefits and Cost-Effectiveness of Asymptomatic Screening for Hypertension and High Cholesterol and Aspirin Counseling for Primary Prevention.
    Annals of family medicine, 2017, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Colorectal Neoplasms; Cost-Benefit Analysis; Counseling; Ethnicity

2017
Impact of USPSTF recommendations for aspirin for prevention of recurrent preeclampsia.
    American journal of obstetrics and gynecology, 2017, Volume: 217, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Diabetes Mellitus, Type 2;

2017
Reducing CV risk in diabetes: An ADA update.
    The Journal of family practice, 2017, Volume: 66, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Benzhydryl Compounds; Cardiovascular Diseases; Contraindications;

2017
Aspirin for Evidence-Based Preeclampsia Prevention trial: effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history.
    American journal of obstetrics and gynecology, 2017, Volume: 217, Issue:5

    Topics: Adult; Algorithms; Aspirin; Body Mass Index; Evidence-Based Medicine; Female; Gestational Age; Human

2017
Factors associated with adverse pregnancy outcomes in women with antiphospholipid syndrome: A multicenter study.
    Journal of reproductive immunology, 2017, Volume: 122

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Female; Heparin; Humans; Hy

2017
Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectio

2017
Assessing Bleeding Risk in Patients Taking Anticoagulants.
    American family physician, 2017, Oct-01, Volume: 96, Issue:7

    Topics: Age Factors; Alcohol Drinking; Anemia; Anticoagulants; Aspirin; Atrial Fibrillation; Decision Suppor

2017
Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia.
    The New England journal of medicine, 2017, 12-14, Volume: 377, Issue:24

    Topics: Aspirin; Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Pregnancy; Risk

2017
Control of cardiovascular disease risk factors among patients with type II diabetes in a primary-care setting in Beijing.
    Journal of the American Society of Hypertension : JASH, 2018, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Beijing; Blood Glucose; Cholesterol, LDL; Cross-Sectional S

2018
Role of Acetyl Salicylic Acid in Controlling the DOCA-Salt Induced Hypertension in Rats by Stimulating the Synthesis of r-Cortexin in the Kidney.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2018, Volume: 25, Issue:1

    Topics: Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Desoxycorticosterone Acetate; Dose-Respon

2018
Acetylsalicylic acid in pregnant women with chronic hypertension.
    American journal of obstetrics and gynecology, 2018, Volume: 218, Issue:4

    Topics: Aspirin; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovasc

2018
Can aldosterone break your heart? Takotsubo cardiomyopathy in a patient with newly diagnosed primary aldosteronism.
    BMJ case reports, 2018, Feb-05, Volume: 2018

    Topics: Aldosterone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agen

2018
Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018.
    Annals of internal medicine, 2018, 05-01, Volume: 168, Issue:9

    Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure Monitoring, Ambulatory; Coronary Disease; Di

2018
Monotherapy of acetylsalicylic acid or warfarin for prevention of ischemic stroke in low-risk atrial fibrillation: A Easter Asian population-based study.
    Cardiology journal, 2019, Volume: 26, Issue:6

    Topics: Adult; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Comparative Effectiveness

2019
Factors associated with lung cancer in COPD patients.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Aged; Aspirin; Asthma; Comorbidity

2018
Aspirin in Primary Prevention of Myocardial Infarction/Angina and Stroke in Hypertensive Patients.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Cardiovascular Diseases; Cross-Sectional S

2018
Chronic Hypertension in Pregnancy: New Concepts for Classification and Management.
    American journal of perinatology, 2019, Volume: 36, Issue:2

    Topics: Adult; Antihypertensive Agents; Aspirin; Chronic Disease; Female; Humans; Hypertension; Hypertension

2019
Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study.
    BMJ open, 2018, 07-30, Volume: 8, Issue:7

    Topics: Acetaminophen; Adult; Antipyretics; Aspirin; Betaine; Body Mass Index; Cross-Sectional Studies; Depr

2018
Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: Adaptive Immunity; Angiotensin II; Animals; Aspirin; Biomarkers; Blood Pressure; Blood Vessels; Card

2019
A Young Woman With Chest Pain.
    JAMA, 2018, Dec-18, Volume: 320, Issue:23

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aortic Dissection; Aspirin; Chest Pain; Clopidogrel;

2018
Association of intrauterine exposure to aspirin and blood pressure at 7 years of age: a secondary analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2019, Volume: 126, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Child; Female; Humans; Hypertensio

2019
Time-Dependent Hypotensive Effect of Aspirin in Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:12

    Topics: Animals; Antihypertensive Agents; ARNTL Transcription Factors; Aspirin; Blood Platelets; Blood Press

2018
Simultaneous transient global amnesia and Takotsubo syndrome after death of a relative: a case report.
    Journal of medical case reports, 2019, Jan-25, Volume: 13, Issue:1

    Topics: Amnesia, Transient Global; Antihypertensive Agents; Aspirin; Atorvastatin; Benzimidazoles; Biphenyl

2019
An aspirin a day in pregnancy keeps childhood hypertension away?
    BJOG : an international journal of obstetrics and gynaecology, 2019, Volume: 126, Issue:5

    Topics: Aspirin; Blood Pressure; Child; Female; Humans; Hypertension; Platelet Aggregation Inhibitors; Pregn

2019
Platelet Surface CD62p and Serum Vitamin D Levels are Associated with Clopidogrel Resistance in Chinese Patients with Ischemic Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:5

    Topics: Aged; Asian People; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; China; Clopidogrel; Drug R

2019
Latin American Consensus on the management of hypertension in the patient with diabetes and the metabolic syndrome.
    Journal of hypertension, 2019, Volume: 37, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Cardiovascular Diseases;

2019
Arterial occlusive events in chronic myeloid leukemia patients treated with ponatinib in the real-life practice are predicted by the Systematic Coronary Risk Evaluation (SCORE) chart.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiology; Coronary Occlusion; Decision Support Systems, C

2019
Aspirin Use for Cardiovascular Disease Prevention in an African American Population: Prevalence and Associations with Health Behavior Beliefs.
    Journal of community health, 2019, Volume: 44, Issue:3

    Topics: Aged; Aspirin; Black or African American; Cardiovascular Diseases; Diabetes Mellitus; Female; Health

2019
Do Statins Have a Positive Impact on Patients with Coronary Microvascular Dysfunction on Long-Term Clinical Outcome? A Large Retrospective Cohort Study.
    BioMed research international, 2019, Volume: 2019

    Topics: Aged; Aspirin; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus; Drug-Related Side E

2019
Aspirin for primary prevention in elderly hypertensive patients: to treat or not to treat?
    Journal of hypertension, 2019, Volume: 37, Issue:6

    Topics: Aged; Aspirin; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Primary Preventio

2019
Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks.
    Journal of hypertension, 2019, Volume: 37, Issue:6

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Pressure; Diabetes Mellitus; Dyslipidemias; Female; Hemorrha

2019
Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study.
    Reproductive health, 2019, May-02, Volume: 16, Issue:1

    Topics: Adult; Aspirin; Attitude of Health Personnel; Calcium; Decision Making; Female; General Practitioner

2019
Secondary prevention advices after cardiovascular index event: From drug prescription to risk factors control in real world practice.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2019, 05-20, Volume: 89, Issue:2

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases;

2019
Rates and Risk of Atrial Arrhythmias in Patients Treated With Ibrutinib Compared With Cytotoxic Chemotherapy.
    The American journal of cardiology, 2019, 08-15, Volume: 124, Issue:4

    Topics: Adenine; Age Factors; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibito

2019
Inappropriate drug use in the elderly outpatient population in a West-African metropolitan community
.
    International journal of clinical pharmacology and therapeutics, 2019, Volume: 57, Issue:7

    Topics: Africa, Western; Aged; Aspirin; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertensio

2019
Infertility and pregnancy in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy: More than just primary ovarian failure?
    American journal of reproductive immunology (New York, N.Y. : 1989), 2019, Volume: 82, Issue:4

    Topics: Aspirin; Female; Fertilization in Vitro; Humans; Hypertension; Immunoglobulins, Intravenous; Immunol

2019
Prediction of human genes and diseases targeted by xenobiotics using predictive toxicogenomic-derived models (PTDMs).
    Molecular bioSystems, 2013, Volume: 9, Issue:6

    Topics: Arrhythmias, Cardiac; Aspirin; Benzhydryl Compounds; Bradycardia; Computer Simulation; Databases, Ch

2013
Hypertension as a risk factor for aspirin and clopidogrel resistance in patients with stable coronary artery disease.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2014, Volume: 20, Issue:7

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Hyperte

2014
Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation;

2014
Associations of durations of antiplatelet use and vascular risk factors with the presence of cerebral microbleeds.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Chi-Square Distribution; Como

2014
Epidemiology of atrial fibrillation in Turkey: preliminary results of the multicenter AFTER study.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2013, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Electrocardiography; F

2013
Risk factors of superimposed preeclampsia in women with essential chronic hypertension treated before pregnancy.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Antihypertensive Agents; Aspirin; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pre

2013
Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study.
    Cardiovascular diabetology, 2013, May-24, Volume: 12

    Topics: Adult; Aspirin; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Complicat

2013
Pro: "The novel oral anticoagulants should be used as 1st choice for secondary prevention in patients with atrial fibrillation.".
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Diabet

2013
Hyperhomocysteinemia and vascular access thrombosis in hemodialysis patients: a retrospective study.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Aged; Aspirin; Biomarkers; Chi-Square Distribution; Diabetes Complications; Female; Fibrinolytic Age

2013
[A rare case of giant coronary aneurysms involving both coronary arteries: computed tomographic-angiographic findings].
    Giornale italiano di cardiologia (2006), 2013, Volume: 14, Issue:10

    Topics: Aged; Aspirin; Atherectomy, Coronary; Bundle-Branch Block; Coronary Aneurysm; Coronary Angiography;

2013
Concurrent coxibs and anti-platelet therapy unmasks aspirin-exacerbated respiratory disease.
    The European respiratory journal, 2013, Volume: 42, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2 Inhibitors; Dyslipi

2013
Developments in large and midsize vasculitis.
    Rheumatic diseases clinics of North America, 2013, Volume: 39, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Child; Coronary Angiography; Humans; Hyp

2013
Risk Factors and Treatment Strategies in Patients With Retinal Vascular Occlusions.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2015, Volume: 21, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle

2015
Patients with risk factors have higher plasma levels of lysophosphatidic acid: a promising surrogate marker for blood platelet activation.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2014, Volume: 25, Issue:4

    Topics: Aspirin; Biomarkers; Blood Platelets; Cross-Sectional Studies; Female; Humans; Hyperlipidemias; Hype

2014
[I Brazilian Guidelines for cardiovascular prevention].
    Arquivos brasileiros de cardiologia, 2013, Volume: 101, Issue:6 Suppl 2

    Topics: Aspirin; Brazil; Cardiovascular Diseases; Evidence-Based Medicine; Female; Health Promotion; Humans;

2013
Implementation of best medical therapy for cardiovascular risk factors in vascular surgery patients treated in a tertiary referral regional unit.
    International journal of clinical practice, 2014, Volume: 68, Issue:9

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Female; Guideline Adherence; Humans; Hydr

2014
Million hearts: prevalence of leading cardiovascular disease risk factors--United States, 2005-2012.
    MMWR. Morbidity and mortality weekly report, 2014, May-30, Volume: 63, Issue:21

    Topics: Adolescent; Adult; Aged; Aspirin; Cardiovascular Diseases; Female; Health Promotion; Humans; Hyperch

2014
[Benign paroxysmal positional vertigo in a female with arterial hypertension and meningioma].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:4

    Topics: Aged; Aspirin; Benign Paroxysmal Positional Vertigo; Brain; Exercise Movement Techniques; Female; Hu

2014
A calcified left ventricular mass.
    Acta cardiologica, 2014, Volume: 69, Issue:3

    Topics: Aged, 80 and over; Aging; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; At

2014
[The clinical analysis of atrial fibrillation of 1 310 in patients in Urumqi of China].
    Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; China; Comor

2014
Age-related prevalence of diabetes mellitus, cardiovascular disease and anticoagulation therapy use in a urolithiasis population and their effect on outcomes: the Clinical Research Office of the Endourological Society Ureteroscopy Global Study.
    World journal of urology, 2015, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascula

2015
Analysis of periinterventional complications of intracranial angioplasty and stenting: a single center experience.
    European journal of radiology, 2014, Volume: 83, Issue:12

    Topics: Aged; Angioplasty; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Diabetes Complication

2014
Acetylsalicylic acid mitigates erythropoietin-associated blood pressure increase in nonuremic rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:3

    Topics: Anemia; Animals; Aspirin; Blood Pressure; Disease Models, Animal; Drug Monitoring; Erythropoietin; H

2015
Beneficial effects of low-dose aspirin on aortic stiffness in hypertensive patients.
    Vascular medicine (London, England), 2014, Volume: 19, Issue:6

    Topics: Adult; Aged; Aorta; Aspirin; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle

2014
Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012.
    Journal of clinical periodontology, 2015, Volume: 42, Issue:4

    Topics: Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Diabe

2015
Spontaneous iliopsoas haematoma: a complication of hypertensive urgency.
    BMJ case reports, 2015, Feb-26, Volume: 2015

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Transfusion; Diabetes Mellitus, Type 2

2015
The effect of calcium channel blockers on prevention of preeclampsia in pregnant women with chronic hypertension.
    Clinical and experimental obstetrics & gynecology, 2015, Volume: 42, Issue:1

    Topics: Adult; Amlodipine; Aspirin; Birth Weight; Blood Pressure; Calcium Channel Blockers; China; Female; H

2015
Trends in myocardial infarction secondary prevention: The National Health and Nutrition Examination Surveys (NHANES), 1999-2012.
    Journal of the American Heart Association, 2015, Apr-22, Volume: 4, Issue:4

    Topics: Aged; Aspirin; Blood Glucose; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperc

2015
Incidence of Non-Traumatic Subconjunctival Hemorrhage in a Nationwide Study in Taiwan from 2000 to 2011.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Comorbidity; Conjunctiva; Conjunctival Diseases; Eye Hemorr

2015
Long-Term Low-Dose Aspirin Use Reduces Gastric Cancer Incidence: A Nationwide Cohort Study.
    Cancer research and treatment, 2016, Volume: 48, Issue:2

    Topics: Adult; Aged; Aspirin; Cohort Studies; Comorbidity; Diabetes Mellitus, Type 2; Female; Humans; Hypert

2016
Evaluating resistance to acetyl salicylic acid using platelet function test in patients with ischemic stroke at Cipto Mangunkusumo Hospital.
    Acta medica Indonesiana, 2015, Volume: 47, Issue:2

    Topics: Aged; Aspirin; Comorbidity; Cross-Sectional Studies; Drug Resistance; Female; Humans; Hypertension;

2015
J Curve and Cuff Artefact, and Diagnostic Inertia in Resistant Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:1

    Topics: Aspirin; Blood Pressure; Female; Humans; Hypertension; Male; Secondary Prevention; Stroke, Lacunar;

2016
Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013.
    Preventing chronic disease, 2015, Nov-19, Volume: 12

    Topics: Aged; Aspirin; Behavioral Risk Factor Surveillance System; Diabetes Mellitus; Humans; Hypercholester

2015
Value of Coronary Computed Tomography Angiography in Tailoring Aspirin Therapy for Primary Prevention of Atherosclerotic Events in Patients at High Risk With Diabetes Mellitus.
    The American journal of cardiology, 2016, Mar-15, Volume: 117, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index; Coronary Angiography; Coron

2016
Alterations of soluble TWEAK and CD163 concentrations in patients with chronic heart failure.
    Cytokine, 2016, Volume: 80

    Topics: Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aspirin; Case-Control Studies;

2016
[The present status of aspirin use for primary prevention among hypertensive outpatients in China].
    Zhonghua nei ke za zhi, 2016, Apr-01, Volume: 55, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; China; Cross-Sectional Studies; Fibrinolytic Agents; Hospitals; Hu

2016
Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:1

    Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Comorbidity; Diabetes Mellit

2016
Effects of low-dose aspirin in subjects with dyslipidemia.
    Lipids in health and disease, 2016, Jun-16, Volume: 15

    Topics: Adult; Aspirin; C-Reactive Protein; Cholesterol, LDL; Convalescence; Coronary Angiography; Coronary

2016
Evaluation of potential drug- drug interactions among Palestinian hemodialysis patients.
    BMC nephrology, 2016, 07-26, Volume: 17

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Arabs; Aspirin; Calcium Carbonate; Comorbidity; Diabetes

2016
[Towards new targets in the treatment of hypertension?]
    Medecine sciences : M/S, 2016, Volume: 32, Issue:10

    Topics: Aged; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2016
Non-coronary chest pain does not affect long-term mortality: a prospective, observational study using a matched population control.
    BMC family practice, 2016, 11-16, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Case-Control Studies; Cause of Death; Chest Pain;

2016
Preeclampsia and Preterm Birth Associated With Visceral Adiposity in Early Pregnancy.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2017, Volume: 39, Issue:2

    Topics: Adult; Aspirin; Body Mass Index; Chronic Disease; Female; Humans; Hypertension; Intra-Abdominal Fat;

2017
Association Between Prior Aspirin Use and Morphological Features of Culprit Lesions at First Presentation of Acute Coronary Syndrome Assessed by Optical Coherence Tomography.
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Mar-24, Volume: 81, Issue:4

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Aspirin; Case-Control Studies; Dyslipidemias; Female; Hu

2017
Efficacy of aspirin and statins in primary prevention of cardiovascular mortality in uncomplicated hypertensive participants: a Korean national cohort study.
    Journal of hypertension, 2017, Volume: 35 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cause of Death; Co

2017
Long-Term Comparative Outcomes of Patients With Peripheral Artery Disease With and Without Concomitant Coronary Artery Disease.
    The American journal of cardiology, 2017, Apr-15, Volume: 119, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Aspirin; California; Coronary Artery Disease; Diabetes Mellitus;

2017
Secondary prevention of coronary artery disease in urban Indian primary care.
    International journal of cardiology, 2009, Jun-26, Volume: 135, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Coronary Artery Dise

2009
Should you screen--or not? The latest recommendations.
    The Journal of family practice, 2008, Volume: 57, Issue:7

    Topics: Adult; Alcohol Drinking; Anemia, Sickle Cell; Aspirin; Chlamydia Infections; Colorectal Neoplasms; F

2008
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.
    Clinical lung cancer, 2008, Volume: 9, Issue:4

    Topics: Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensiv

2008
Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: a nested, case-control study.
    Arthritis and rheumatism, 2008, Aug-15, Volume: 59, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; An

2008
Usefulness of hypertensive blood pressure response during a single-stage exercise test to predict long-term outcome in patients with peripheral arterial disease.
    The American journal of cardiology, 2008, Oct-01, Volume: 102, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Aspirin; Blood Pressure; Cardiovascular Diseases; Cause of Death;

2008
[Arterial hypertension in pregnancy].
    Revue medicale de Bruxelles, 2008, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Calcium; Dietary Sup

2008
Profile of Sérgio Ferreira.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-09, Volume: 105, Issue:49

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Brazil; History, 20th Century; History, 21st Cent

2008
[Brain hypoperfusion revealed by an ocular ischemic syndrome].
    Journal francais d'ophtalmologie, 2008, Volume: 31, Issue:8

    Topics: Antihypertensive Agents; Aspirin; Atorvastatin; Brain Ischemia; Carotid Artery Thrombosis; Ciliary B

2008
A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels.
    International journal of cardiology, 2010, Sep-03, Volume: 143, Issue:3

    Topics: Adult; Antihypertensive Agents; Aspirin; Female; Humans; Hyperhomocysteinemia; Hypertension; Lipopro

2010
Primary CNS lymphoma presenting as fever of unknown origin.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cra

2009
["Diabetes in Germany"(DIG) study. A prospective 4-year-follow-up study on the quality of treatment for type 2 diabetes in daily practice].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Diabetes

2009
Transient ischemic attack associated with stenosis of accessory middle cerebral artery: a case report.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:7

    Topics: Aphasia; Aspirin; Cerebral Angiography; Clopidogrel; Constriction, Pathologic; Humans; Hypertension;

2009
Rosuvastatin in patients with elevated C-reactive protein.
    The New England journal of medicine, 2009, Mar-05, Volume: 360, Issue:10

    Topics: Aspirin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Female; Fluorobenzenes; Guideline

2009
Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation.
    Cardiovascular research, 2009, Jul-01, Volume: 83, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Blood Pressure; Blood Ve

2009
Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin.
    Journal of neurology, neurosurgery, and psychiatry, 2009, Volume: 80, Issue:4

    Topics: Aged; Aspirin; Brain Ischemia; Cerebral Arteries; Dipyridamole; Drug Therapy, Combination; Female; H

2009
Clopidogrel for preventing cardiovascular events.
    The Mount Sinai journal of medicine, New York, 2009, Volume: 76, Issue:2

    Topics: Aspirin; Clopidogrel; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Evidence-Based Medicine;

2009
Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women.
    Circulation, 2009, Apr-28, Volume: 119, Issue:16

    Topics: Adult; Antioxidants; Aspirin; Atrial Fibrillation; Blood Pressure; Cohort Studies; Diastole; Female;

2009
Acute myocardial infarction with sumatriptan: a case report and review of the literature.
    Headache, 2009, Volume: 49, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aspirin; Coronary Vasospasm; Coronary Vessels; Echocardi

2009
Antiplatelet effects of n-3 polyunsaturated fatty acids compared with aspirin: a pilot study with whole-blood aggregometry.
    Thrombosis research, 2009, Volume: 124, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index; Cardiovascular Diseases; Co

2009
Profile of cardiovascular risk factors and mortality in patients with symptomatic peripheral arterial disease.
    Clinics (Sao Paulo, Brazil), 2009, Volume: 64, Issue:4

    Topics: Aged; Aspirin; Brazil; Coronary Artery Disease; Female; Humans; Hypertension; Kaplan-Meier Estimate;

2009
Clopidogrel versus low-dose aspirin as risk factors for epistaxis.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2009, Volume: 34, Issue:3

    Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Epistaxis; Humans; Hypertension; Myocardial

2009
[Oral anticoagulant use in patients with atrial fibrillation].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Female; Humans; Hypertension; International Norm

2009
Diabetes mellitus is associated with increased ex vivo-platelet aggregation and decreased response to aspirin - antithrombotic potential of ACE-inhibitors and AT1-antagonists.
    Platelets, 2009, Volume: 20, Issue:5

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Coronary Disease; Diabetes Mellitus, Type 2

2009
Spontaneous spinal epidural hematoma: an urgent complication of adding clopidogrel to aspirin therapy.
    Journal of the neurological sciences, 2009, Oct-15, Volume: 285, Issue:1-2

    Topics: Aspirin; Clopidogrel; Coronary Stenosis; Decompression, Surgical; Drug Interactions; Hematoma, Epidu

2009
Cilostazol, a phosphodiesterase inhibitor, attenuates photothrombotic focal ischemic brain injury in hypertensive rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:2

    Topics: Animals; Aspirin; Brain Ischemia; Cells, Cultured; Cerebrovascular Circulation; Cilostazol; Clopidog

2010
Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry.
    European heart journal, 2010, Volume: 31, Issue:2

    Topics: Aged; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Diabetic Angiopathies; Dyslipidemias

2010
Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E

2010
Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E

2010
Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E

2010
Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E

2010
Letter by Barrios et al regarding article, "Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women".
    Circulation, 2010, Feb-09, Volume: 121, Issue:5

    Topics: Adult; Antioxidants; Aspirin; Atrial Fibrillation; Blood Pressure; Cohort Studies; Diastole; Female;

2010
Health care services provided during physician office visits for hypertension: differences by specialty.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Feb-01, Volume: 12, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Aspirin; C

2010
Aspirin, non-aspirin analgesics and the risk of hypertension in the SUN cohort.
    Revista espanola de cardiologia, 2010, Volume: 63, Issue:3

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Hypertension; I

2010
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:1

    Topics: Animals; Aspirin; Biomarkers; Blood Pressure; Brain; Endothelium, Vascular; Fluorobenzenes; Hyperten

2010
Approach to the patient who is intolerant of statin therapy.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atorvastatin; Corona

2010
Low-dose acetylsalicylic acid and blood pressure control in drug-treated hypertensive patients.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2011, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; As

2011
Clinico-pathologic conference: case 6.
    Head and neck pathology, 2009, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell;

2009
Aspirin use in elderly women receiving medication therapy management services.
    Advances in therapy, 2010, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Comorbidity; Contraindications; Diabetes

2010
Aspirin and the prevention of cardiovascular disease in chronic kidney disease: time to move forward?
    Journal of the American College of Cardiology, 2010, Sep-14, Volume: 56, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Chronic Disease; Creatinine; Glomerular Filtration Rate; Hemorrhag

2010
[Aggregation activity of platelets in various periods of ischemic stroke].
    Kardiologiia, 2010, Volume: 50, Issue:8

    Topics: Aged; Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Brain Ischemia; Female; Humans;

2010
"War and Peace" with Barrett's esophagus.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Aged; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Barrett Esophagus; Celeco

2011
Update in pre-eclampsia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87 Suppl 3

    Topics: Antihypertensive Agents; Antioxidants; Ascorbic Acid; Aspirin; Blood Pressure; Female; Humans; Hyper

2004
Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report.
    Archives of neurology, 2011, Volume: 68, Issue:3

    Topics: Aged; Angiography; Antihypertensive Agents; Aorta; Aspirin; Circle of Willis; Connective Tissue Dise

2011
Is testing for aspirin response worthwhile in high-risk pregnancy?
    European journal of obstetrics, gynecology, and reproductive biology, 2011, Volume: 157, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Canada; Diabetes Complications; Dose-Respon

2011
Atrial fibrillation, is warfarin the only option for stroke prevention?
    JPMA. The Journal of the Pakistan Medical Association, 2011, Volume: 61, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Anticoagulants; Aspirin; Atrial Fibrillation; Biphenyl Comp

2011
Stroke in Malawi--what do we know about it and how should we manage it? Manage it?
    Malawi medical journal : the journal of Medical Association of Malawi, 2010, Volume: 22, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Blood Pressure; Fe

2010
Ischemic stroke in patients receiving aspirin.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2012, Volume: 21, Issue:8

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Argentina; Aspirin; Brain Ischemia; Chi-Square Dis

2012
Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension.
    American journal of hypertension, 2011, Volume: 24, Issue:11

    Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase

2011
Comparison of characteristics, management practices, and outcomes of patients between the global registry and the gulf registry of acute coronary events.
    The American journal of cardiology, 2011, Nov-01, Volume: 108, Issue:9

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Aspiri

2011
The effect of admission blood pressure on the prognosis of patients with intracerebral hemorrhage that occurred during treatment with aspirin, warfarin, or no drugs.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Blood Pressure; Ce

2012
First-fill medication discontinuations and nonadherence to antihypertensive therapy: an observational study.
    American journal of hypertension, 2012, Volume: 25, Issue:2

    Topics: Age Factors; Aged; Antidepressive Agents; Antihypertensive Agents; Aspirin; Chronic Disease; Depress

2012
Bead-like coronary spasm.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Aspirin; Bradycardia; Calcium Channel Blockers; Chest Pain; Coronary Angiography; Coronary Stenosis;

2012
Role for the left atrial appendage occlusion device in managing thromboembolic risk in atrial fibrillation.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Cardiac Catheterization; Femal

2012
Risk factors for colonic diverticular hemorrhage: Japanese multicenter study.
    Digestion, 2012, Volume: 85, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Body Mass Index; Case-Control Studies; Diverticulum, Colon; Female

2012
Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Drug Therapy, Combi

2012
Primary prevention with aspirin in type 2 diabetic patients. Searching for the right spot.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:6

    Topics: Aspirin; Blood Pressure; Cardiovascular Agents; Cerebrovascular Disorders; Diabetes Mellitus, Type 2

2012
Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 2; Diagnosis; Female; Gene

2012
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
    Journal of neurology, 2012, Volume: 259, Issue:10

    Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulc

2012
The Million Hearts™ initiative: why psychosocial nurses should care.
    Journal of psychosocial nursing and mental health services, 2012, Volume: 50, Issue:5

    Topics: Aspirin; Cholesterol; Comorbidity; Health Promotion; Humans; Hypertension; Mental Disorders; Myocard

2012
What is the relationship between effects of aspirin, statins, and C-reactive protein?
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Female; Humans; Hypertension;

2012
Impact of low-dose aspirin on coronary artery spasm as assessed by intracoronary acetylcholine provocation test in Korean patients.
    Journal of cardiology, 2012, Volume: 60, Issue:3

    Topics: Acetylcholine; Age Factors; Aspirin; Coronary Angiography; Coronary Vasospasm; Diabetes Complication

2012
Relationship between endothelial functions and acetylsalicylic acid resistance in newly diagnosed hypertensive patients.
    Clinical cardiology, 2012, Volume: 35, Issue:12

    Topics: Adult; Aspirin; Drug Resistance; Echocardiography; Endothelium, Vascular; Female; Humans; Hypertensi

2012
I read that common over-the-counter pain medications increase the risk of heart attack and stroke. What can I take for my aching hands? I think I have arthritis, but it's not bad enough to see a rheumatologist yet.
    Heart advisor, 2011, Volume: 14, Issue:1

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Humans; Hypertension; No

2011
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cor

2012
The relationship of plasma ADMA levels with cardiac functions and metabolic parameters in peritoneal dialysis patients.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:3

    Topics: Adolescent; Aged; Arginine; Aspirin; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studi

2013
[The risk factors for colonic diverticular bleeding].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2012, Volume: 60, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calci

2012
Exfoliative esophagitis in a patient with metastatic renal cell carcinoma during sunitinib treatment.
    Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Carcinoma, Renal Cell; Cyclooxy

2013
Insulin resistance, oxidative stress and aspirin: therapeutic implications?
    Journal of hypertension, 2002, Volume: 20, Issue:7

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Glucose; Humans; Hyperglycemia; Hypertension; Insulin R

2002
Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats.
    Journal of hypertension, 2002, Volume: 20, Issue:7

    Topics: Animals; Aorta; Aspirin; Blood Glucose; Blood Pressure; Body Weight; Canada; Cyclooxygenase Inhibito

2002
[The effect of acetylsalicylic acid on hypotensive action of enalapril in hypertensive patients].
    Przeglad lekarski, 2002, Volume: 59, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Press

2002
Pravastatin and Aspirin.
    Circulation, 2002, Aug-06, Volume: 106, Issue:6

    Topics: Advisory Committees; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Drug Packaging; Drug T

2002
Frequency of analgesic use and risk of hypertension in younger women.
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies;

2002
Frequency of analgesic use and risk of hypertension in younger women.
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies;

2002
Frequency of analgesic use and risk of hypertension in younger women.
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies;

2002
Frequency of analgesic use and risk of hypertension in younger women.
    Archives of internal medicine, 2002, Oct-28, Volume: 162, Issue:19

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies;

2002
Coronary and cardiovascular risk estimation in uncomplicated mild hypertension. A comparison of risk assessment methods.
    Journal of hypertension, 2002, Volume: 20, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Female; Health Status Ind

2002
Nonnarcotic analgesic use and the risk of hypertension in US women.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2002
[A case of familial restrictive cardiomyopathy].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Atenolol; Atrial Fibrillation

2002
[Baseline characteristics and management of patients less than 45 years of age hospitalized for acute coronary syndromes: results from the nationwide French PREVENIR 1 and PREVENIR 2 studies].
    Annales de cardiologie et d'angeiologie, 2002, Volume: 51, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Angina, Unstable; Angiotensin-Converting Enzyme Inh

2002
[Interaction of angiotensin converting enzyme inhibitors with nonsteroidal antiinflammatory drugs].
    Kardiologiia, 2002, Volume: 42, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Syn

2002
Antiplatelet effects of angiotensin-converting enzyme inhibitors compared with aspirin and clopidogrel: a pilot study with whole-blood aggregometry.
    American heart journal, 2003, Volume: 145, Issue:2

    Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspiri

2003
By the way, doctor. I recently read that Tylenol and anti-inflammatory drugs can cause high blood pressure. This doesn't leave me with many pain relief options. What do you suggest?
    Harvard women's health watch, 2003, Volume: 10, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Hypertension; Nonpr

2003
Differential effect of aspirin on platelet aggregation in patients with coronary artery disease in relation with associated risk factors.
    Japanese heart journal, 2003, Volume: 44, Issue:1

    Topics: Adult; Aged; Aspirin; Coronary Disease; Diabetic Angiopathies; Double-Blind Method; Humans; Hyperlip

2003
I'm a 65-year-old man with high blood pressure and a family history of stroke. Which stroke-prevention medication would be better for me--aspirin or clopidogrel (Plavix)?
    Health news (Waltham, Mass.), 2003, Volume: 9, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Family Health; Humans; Hypertension; Life Style; Male; Platelet Aggregat

2003
Smoking and the risk of hemorrhagic stroke in men.
    Stroke, 2003, Volume: 34, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Body Mass Ind

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
A rhythm method for better health. Being aware of your body clock could help protect you from a heart attack or stroke and let you time your medications for when they'll do the most good.
    Harvard heart letter : from Harvard Medical School, 2003, Volume: 13, Issue:8

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Biological Clocks; Blood Pressure; Chron

2003
Potential adverse interaction between aspirin and lisinopril in hypertensive rats.
    Human & experimental toxicology, 2003, Volume: 22, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Blood Pressure; Body Weight; Drug Antago

2003
Nonsteroidal anti-inflammatory drugs as risk factors for spontaneous intracerebral hemorrhage and aneurysmal subarachnoid hemorrhage.
    Stroke, 2003, Volume: 34, Issue:6

    Topics: Age Factors; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control

2003
[Study on hypertension optimal treatment (HOT) and its inspiration].
    Zhonghua nei ke za zhi, 1999, Volume: 38, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Humans; Hypertension

1999
Niacin and the National Cholesterol Education Program Adult Treatment Panel III Guidelines: case studies.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jul-01, Volume: 60, Issue:13 Suppl 2

    Topics: Aspirin; Atenolol; Blood Chemical Analysis; Coronary Disease; Female; Humans; Hyperlipidemias; Hyper

2003
[Stroke is not equal to stroke. Keep track of the causes].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adult; Antihypertensive Agents; Aspirin; Carotid Artery, Common; Carotid Artery, External; Carotid S

2003
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic

2003
[ACUTE DIGESTIVE HEMORRHAGES].
    El Dia medico, 1963, Sep-19, Volume: 35

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Aspirin; Gastrointestinal Hemo

1963
SEVERE RHEUMATIC MITRAL INSUFFICIENCY IN CHILDHOOD AMENABLE TO SURGERY.
    Pediatrics, 1964, Volume: 33

    Topics: Aspirin; Blood Circulation; Cardiac Surgical Procedures; Child; Digitalis Glycosides; Electrocardiog

1964
THE EFFECT OF SALURETICS ON PULSE RATE, BLOOD PRESSURE AND ELECTROCARDIOGRAM DURING EXERCISE IN NORMAL SUBJECTS.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Aspirin; Biomedical Research; Blood; Blood Pressure; Blood Pressure Determination; Chlorides; Chlort

1964
CAUSAL INFLUENCES IN HAEMATEMESIS AND MELAENA.
    Gut, 1965, Volume: 6

    Topics: Alcoholic Beverages; Arteriosclerosis; Aspirin; Blood Group Antigens; Duodenal Ulcer; Genetics, Medi

1965
Summaries for patients. Gastrointestinal side effects of rofecoxib and naproxen.
    Annals of internal medicine, 2003, Oct-07, Volume: 139, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors

2003
Secretory dysfunction of vascular endothelium limits the effect of angiotensin converting enzyme inhibitor quinapril on aggregation of erythrocytes in experimental hypertension.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2003, Volume: 54, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Blood Pressure; Bradykinin; Disease Mode

2003
Introduction to monitoring. What is what you prescribed actually doing?
    Australian family physician, 2003, Volume: 32, Issue:10

    Topics: Acetaminophen; Aged; Aspirin; Australia; Celecoxib; Drug Interactions; Drug Therapy, Combination; Fa

2003
Preventing diabetic retinopathy through control of systemic factors.
    Current opinion in ophthalmology, 2003, Volume: 14, Issue:6

    Topics: Anticoagulants; Aspirin; Diabetic Angiopathies; Diabetic Retinopathy; Disease Progression; Female; G

2003
Prevention of cardiovascular disease: an evidence-based clinical aid.
    The Medical journal of Australia, 2004, Feb-16, Volume: 180, Issue:4

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Evidence-Based Medicine; Guideline Adhere

2004
Aspirin, chance, and results in relation to blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Blood Pressure Monitoring, Ambulat

2004
Coronary risk scores.
    Lancet (London, England), 2004, Feb-14, Volume: 363, Issue:9408

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Coronary Disease; Humans; Hypertension;

2004
Hypertension and insulin resistance are not directly related in obese dogs.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Rest

2004
Should hypertensive patients take aspirin? A report from the Food and Drug Administration.
    Journal of clinical hypertension (Greenwich, Conn.), 2004, Volume: 6, Issue:3

    Topics: Aspirin; Clinical Trials as Topic; Humans; Hypertension; Platelet Aggregation Inhibitors; Practice G

2004
British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary.
    BMJ (Clinical research ed.), 2004, Mar-13, Volume: 328, Issue:7440

    Topics: Algorithms; Antihypertensive Agents; Aspirin; Blood Pressure Determination; Cardiovascular Diseases;

2004
Secondary prevention of stroke: more than just aspirin or warfarin.
    Age and ageing, 2004, Volume: 33, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Fibrinolytic Agents; Humans; Hypertension; Secondary Prevention; Stro

2004
Aspirin, superoxide anions and development of hypertension.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Cells, Cultured; Hyp

2004
Prevention of angiotensin II-induced hypertension, cardiovascular hypertrophy and oxidative stress by acetylsalicylic acid in rats.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Body Weight; Cells,

2004
Consensus statement for the prevention of vascular disease.
    Australian family physician, 2004, Volume: 33, Issue:4

    Topics: Aged; Aspirin; Atrial Fibrillation; Australia; Diabetes Complications; Diabetes Mellitus; Family Pra

2004
[Management of stroke in a ward of internal medicine. Limits and prospects].
    Recenti progressi in medicina, 2004, Volume: 95, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia;

2004
Will changes in primary care improve health outcomes? Modelling the impact of financial incentives introduced to improve quality of care in the UK.
    Quality & safety in health care, 2004, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Cholesterol; Fem

2004
Preventing recurrent events long term after coronary artery bypass graft: suboptimal use of medications in a population study.
    American heart journal, 2004, Volume: 147, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin;

2004
Cardiovascular disease risk reduction in the Behavioral Risk Factor Surveillance System.
    American journal of preventive medicine, 2004, Volume: 27, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Exercise; Feeding Behavior; Female; Healt

2004
Risk factors and in-hospital outcomes in stroke and myocardial infarction patients.
    BMC public health, 2004, Jul-05, Volume: 4

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Croa

2004
The Willis Lecture 2003: evaluating treatments for stroke patients too slowly: time to get out of second gear.
    Stroke, 2004, Volume: 35, Issue:9

    Topics: Angioplasty; Anticoagulants; Antihypertensive Agents; Aspirin; Carotid Stenosis; Clinical Trials as

2004
Epistaxis.
    Nursing, 2004, Volume: 34, Issue:8

    Topics: Aspirin; Catheterization; Emergency Treatment; Epistaxis; Humans; Hypertension; Male; Middle Aged; N

2004
Today's guidance.
    Diabetic medicine : a journal of the British Diabetic Association, 2004, Volume: 21 Suppl 4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Diabetes Mellitus, Type 2; Guide

2004
Explaining the increase in coronary heart disease mortality in Beijing between 1984 and 1999.
    Circulation, 2004, Sep-07, Volume: 110, Issue:10

    Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Cardiovascular Agents; China; Coronary Disease; Devel

2004
[Statins in hypertension].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2004, Sep-23, Volume: 124, Issue:18

    Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Benzothiadiazines; Diuretics; Drug Thera

2004
Effects of cyclooxygenase inhibition on endothelial function in hypertensive patients treated with angiotensin-converting enzyme inhibitors.
    Clinical cardiology, 2004, Volume: 27, Issue:9

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspir

2004
Pattern of drug utilization among hypertensives in a Nigerian teaching hospital.
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:1

    Topics: Aspirin; Cross-Sectional Studies; Diabetes Complications; Diuretics; Drug Combinations; Drug Interac

2005
Canadian Hypertension Education Program. Brief overview of 2004 recommendations.
    Canadian family physician Medecin de famille canadien, 2004, Volume: 50

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Canada; Cardiovascular D

2004
Aspirin resistance in vitro and hypertension in stroke patients.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:11

    Topics: Aged; Aspirin; Blood Coagulation Tests; Drug Resistance; Female; Humans; Hypertension; Male; Middle

2004
A 7-year-old girl with arthritis and hypertension.
    Pediatric annals, 2004, Volume: 33, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Arthritis, Infectious; Arthritis, J

2004
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant

2005
[Secondary prevention of stroke].
    No to shinkei = Brain and nerve, 2004, Volume: 56, Issue:11

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Diabetes Complications; Guideline Adherence; Humans; H

2004
Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index; C-Reactive Protein; Cardiov

2005
[Characteristic features of the pathogenesis and treatment of coronary heart diseases, heart failure and arterial hypertension in patients with diabetes mellitus].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Blood Glucose; Calcium Channel Blockers; Clinical Trial

2005
Glycoprotein IIIA gene (PlA) polymorphism and aspirin resistance: is there any correlation?
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6

    Topics: Adult; Aged; Alleles; Aspirin; Drug Resistance; Dyslipidemias; Female; Gene Frequency; Genotype; Hum

2005
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cult

2005
Prevalence of aspirin resistance in patients with type 2 diabetes.
    Acta diabetologica, 2005, Volume: 42, Issue:2

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies;

2005
[Aspirin for primary prevention of cardiovascular diseases].
    Zhonghua yi xue za zhi, 2005, Apr-06, Volume: 85, Issue:13

    Topics: Aspirin; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Platelet Aggregatio

2005
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Aspirin; Blood Pressure; Cyclooxygenase Inhi

2005
[Prophylaxis of stroke].
    Praxis, 2005, Jul-27, Volume: 94, Issue:30-31

    Topics: Age Factors; Aged; Angioplasty, Balloon; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fi

2005
Analgesic use and risk of subsequent hypertension in apparently healthy men.
    Archives of internal medicine, 2005, Sep-12, Volume: 165, Issue:16

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N

2005
Aspirin: a novel antihypertensive drug? Or two birds with one stone?
    Journal of the American College of Cardiology, 2005, Sep-20, Volume: 46, Issue:6

    Topics: Aspirin; Humans; Hypertension

2005
Outcomes of acute coronary syndrome in a large Canadian cohort: impact of chronic renal insufficiency, cardiac interventions, and anemia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Anemia; Angina, Unstable; Angiotensin-Converting Enzyme In

2005
Association between body mass index and CKD in apparently healthy men.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspirin; beta Carotene; Body Mass Index; Cardiovascular Diseases; Chronic Disease; Cohort Stu

2005
Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability.
    International psychogeriatrics, 2005, Volume: 17, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Brain; Dementia, Va

2005
Acute pain in the tip of the index finger.
    The American journal of medicine, 2005, Volume: 118, Issue:11

    Topics: Acute Disease; Amlodipine; Arterial Occlusive Diseases; Aspirin; Cyanosis; Diagnostic Errors; Female

2005
The cardiovascular pharmacology of COX-2 inhibition.
    Hematology. American Society of Hematology. Education Program, 2005

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Blood Pressure; Cardiova

2005
NSAIDs and cardiovascular risk.
    Cell metabolism, 2005, Volume: 2, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular System; Clinical Trials as Topic; D

2005
Infarct-related coronary artery patency and medication use prior to ST-segment elevation myocardial infarction.
    The American journal of cardiology, 2006, Jan-01, Volume: 97, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Coronary Angiography

2006
Urticaria-angioedema reaction caused by propafenone.
    Allergy, 2006, Volume: 61, Issue:2

    Topics: Angioedema; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Drug Hypersensitivity; Enalapril;

2006
Botulinum toxin A for the treatment of greater occipital neuralgia and trigeminal neuralgia: a case report with pathophysiological considerations.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Anxiety; Aspirin; Botulinum Toxins, Type A; Caffeine; Colitis, Ulc

2006
Aspirin therapy as primary prevention in hypertensive patients at Srinagarind hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:12

    Topics: Aged; Aspirin; Cardiovascular Diseases; Female; Humans; Hypertension; Male; Middle Aged; Platelet Ag

2005
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95, Issue:4

    Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin

2006
Evaluating and treating cardiometabolic risk factors: a case discussion.
    Pharmacotherapy, 2006, Volume: 26, Issue:5 Pt 2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Diet; Dyslipidemias; Exercise; Female; Heart Dise

2006
Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease.
    World journal of gastroenterology, 2006, May-14, Volume: 12, Issue:18

    Topics: Aged; Aspirin; Body Mass Index; Comorbidity; Coronary Artery Disease; Dose-Response Relationship, Dr

2006
The rate of checking urine microalbumin and aspirin primary prevention in type 2 DM.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:5

    Topics: Albuminuria; Aspirin; Atherosclerosis; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Humans; Hyp

2006
[Bleeding after cardiac surgery: risk factors, frequency, and outcomes].
    Medicina (Kaunas, Lithuania), 2006, Volume: 42, Issue:7

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Cardiac Surgical Procedures; Diabetes Mellitus,

2006
Secondary prevention of coronary heart disease in primary health care.
    Bosnian journal of basic medical sciences, 2006, Volume: 6, Issue:2

    Topics: Adult; Aged; Aspirin; Body Mass Index; Coronary Disease; Female; Humans; Hypercholesterolemia; Hyper

2006
New ways to prevent stroke.
    Heart advisor, 2006, Volume: 9, Issue:7

    Topics: Aspirin; Humans; Hypertension; Platelet Aggregation Inhibitors; Risk Assessment; Smoking Prevention;

2006
Effects of aspirin on intra-platelet vascular endothelial growth factor, angiopoietin-1, and p-selectin levels in hypertensive patients.
    American journal of hypertension, 2006, Volume: 19, Issue:9

    Topics: Aged; Angiopoietin-1; Aspirin; Biomarkers; Blood Platelets; Blood Pressure; Case-Control Studies; Cy

2006
Validation studies of the health improvement network (THIN) database for pharmacoepidemiology research.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplasms; Databases

2007
[Finding the right platelet anti-aggregant prescription for type-2 diabetes patients, according to the ADA 2003 criteria].
    Atencion primaria, 2006, Oct-31, Volume: 38, Issue:7

    Topics: Adult; Aged; Aspirin; Body Mass Index; Cardiovascular Diseases; Confidence Intervals; Diabetes Melli

2006
Research for bleeding tendency in patients presenting with significant epistaxis.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:1

    Topics: Aspirin; Biomarkers; Blood Coagulation Disorders, Inherited; Epistaxis; Family Health; Female; Hemor

2007
Elevated platelet microparticle levels in nonvalvular atrial fibrillation: relationship to p-selectin and antithrombotic therapy.
    Chest, 2007, Volume: 131, Issue:3

    Topics: Aged; Aspirin; Atrial Fibrillation; Blood Coagulation Factors; Blood Platelets; Cardiovascular Disea

2007
Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.
    Circulation, 2007, May-15, Volume: 115, Issue:19

    Topics: Adult; Arachidonic Acid; Aspirin; beta-Thromboglobulin; Black or African American; Blood Platelets;

2007
Changes in the use of cardiovascular medicines in the elderly aged 75 years or older--a population-based Kuopio 75+ study.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:3

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Bl

2007
Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels.
    European journal of epidemiology, 2007, Volume: 22, Issue:7

    Topics: Adult; Aged; Anticholesteremic Agents; Aspirin; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Co

2007
Aspirin for hypertension?
    Harvard men's health watch, 2007, Volume: 11, Issue:12

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Chronotherapy; Humans; Hypertension; Randomized Co

2007
Effect of statin drugs and aspirin on open-angle glaucoma progression.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:6

    Topics: Aspirin; Disease Progression; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Hydroxymethyl

2007
Aspirin prevents and partially reverses adrenocorticotropic hormone-induced hypertension in the rat.
    American journal of hypertension, 2007, Volume: 20, Issue:11

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressu

2007
Clinical decisions. Management of stable coronary disease.
    The New England journal of medicine, 2007, Oct-25, Volume: 357, Issue:17

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Coronary Disease; Diabetes Me

2007
[A study on the recurrence of ischemic stroke in nonvalvular atrial fibrillation].
    Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Cohort Studies; Female; Follow-Up Stud

2007
The patterns of antihypertensive drug prescription by cardiologists in Kerman province of Iran, 2006.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:2

    Topics: Adult; Aged; Ambulatory Care; Antihypertensive Agents; Aspirin; Cardiology; Cardiovascular Diseases;

2008
In vivo platelet activation is responsible for enhanced vascular endothelial growth factor levels in hypertensive patients.
    Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 388, Issue:1-2

    Topics: Aged; Aspirin; Female; Humans; Hypertension; Male; P-Selectin; Platelet Activation; Solubility; Vasc

2008
[Beneficial effects of statins and angiotensin converting enzyme inhibitors on aggregability of red blood cells in hypertensive patients].
    Folia medica Cracoviensia, 2006, Volume: 47, Issue:1-4

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin;

2006
Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Animals; Aspirin; Blood Pressure; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 In

2008
Vertebral artery dissection: not a rare cause of stroke in the young.
    Age and ageing, 2008, Volume: 37, Issue:3

    Topics: Adult; Amlodipine; Anticoagulants; Antihypertensive Agents; Aspirin; Craniocerebral Trauma; Female;

2008
Antithrombotic therapy in peripheral arterial disease.
    Cardiology clinics, 2008, Volume: 26, Issue:2

    Topics: Anticoagulants; Aspirin; Atherosclerosis; Cilostazol; Clopidogrel; Comorbidity; Diabetic Angiopathie

2008
Overview of recent clinical and methodological advances from clinical trials of cardiovascular disease.
    Controlled clinical trials, 1982, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Di

1982
Secondary prevention of coronary heart disease.
    Acta cardiologica, 1984, Volume: 39, Issue:4

    Topics: Adrenergic beta-Antagonists; Anticoagulants; Aspirin; Coronary Disease; Diabetes Mellitus; Feeding B

1984
Treatment of cerebral ischemia.
    Comprehensive therapy, 1981, Volume: 7, Issue:4

    Topics: Aspirin; Brain Ischemia; Carotid Arteries; Dicumarol; Dipyridamole; Endarterectomy; Heart Murmurs; H

1981
[Medical therapy of peripheral arteriopathies].
    La Clinica terapeutica, 1984, Feb-29, Volume: 108, Issue:4

    Topics: Arterial Occlusive Diseases; Aspirin; Blood Coagulation; Blood Viscosity; Erythrocytes; Humans; Hype

1984
[Therapy of peripheral arterial occlusive diseases. Round table conference].
    Schweizerische medizinische Wochenschrift, 1983, Dec-10, Volume: 113, Issue:49

    Topics: Alprostadil; Angioplasty, Balloon; Anti-Bacterial Agents; Anticoagulants; Arterial Occlusive Disease

1983
Cardiovascular disease and the need for prophylaxis.
    Journal of the American Medical Women's Association (1972), 1980, Volume: 35, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Cholesterol; Humans; Hypertension; Middle Aged; Smoking

1980
[Anti-aggregating action and clinical effect of small doses of aspirin in the treatment of patients with arterial hypertension and cerebrovascular disorders].
    Klinicheskaia meditsina, 1983, Volume: 61, Issue:9

    Topics: Adult; Aspirin; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged; Platelet

1983
[Preventive medical treatment of cerebral ischemic accidents related to atherosclerosis].
    La Revue du praticien, 1984, Apr-12, Volume: 34, Issue:21 Pt 2

    Topics: Arteriosclerosis; Aspirin; Brain Ischemia; Female; Humans; Hypertension; Male; Middle Aged; Platelet

1984
Arachidonic acid metabolites, hypertension and arteriosclerosis.
    Klinische Wochenschrift, 1982, May-17, Volume: 60, Issue:10

    Topics: Arachidonic Acids; Arteriosclerosis; Aspirin; Dinoprostone; Humans; Hypertension; Platelet Adhesiven

1982
Modification of anti-hypertensive action of verapamil by inhibition of endogenous prostaglandin synthesis.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 9, Issue:2

    Topics: Aspirin; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins; Verapam

1982
Failure of aspirin to modify the hypotensive action of captopril in spontaneously hypertensive rats.
    Clinical and experimental pharmacology & physiology, 1981, Volume: 8, Issue:4

    Topics: Animals; Aspirin; Blood Pressure; Captopril; Hypertension; Male; Proline; Rats; Rats, Inbred Strains

1981
Secondary prevention in myocardial infarction survivors.
    Circulation, 1982, Volume: 65, Issue:1

    Topics: Anticoagulants; Aspirin; Diabetes Mellitus; Diet, Reducing; Humans; Hypertension; Lipids; Myocardial

1982
Enhanced platelet turnover and prostaglandin production in spontaneously hypertensive rats.
    Thrombosis research, 1982, Aug-01, Volume: 27, Issue:3

    Topics: Animals; Aspirin; Blood Platelets; Erythrocyte Count; Hematocrit; Hypertension; Male; Malondialdehyd

1982
Growth rate differences between arterial smooth muscle cells cultivated from rat impaired by short--or long--term hypertension respectively.
    Artery, 1980, Volume: 8, Issue:4

    Topics: Animals; Aorta, Thoracic; Aspirin; Cell Division; Desoxycorticosterone; Hypertension; Muscle, Smooth

1980
Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Arteries; Aspirin; Cerebrovascular Disorders; Female; Humans; Hypertension;

1981
Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans

1981
For your stroke-prone patients: a guide to drug treatment.
    Geriatrics, 1980, Volume: 35, Issue:2

    Topics: Aged; Antihypertensive Agents; Aspirin; Brain Diseases; Cerebral Angiography; Cerebrovascular Disord

1980
Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin.
    Thrombosis and haemostasis, 1980, Aug-29, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Cerebrovascular Disorders; Dos

1980
Nitric oxide mediates the hypertensive response to a modified hemoglobin solution (DCLHb) in rats.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspirin; Hemodynamics; Hemoglobins; Hypertension; Mal

1994
Epidemiological feasibility of cardiovascular primary prevention in general practice: a trial of vitamin E and aspirin. Collaborative group of the Primary Prevention Project.
    Journal of cardiovascular risk, 1995, Volume: 2, Issue:2

    Topics: Aged; Arteriosclerosis; Aspirin; Cardiovascular Diseases; Clinical Protocols; Contraindications; Dia

1995
Conservative management of severe chronic hypertension in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1994, Volume: 57, Issue:3

    Topics: Adult; Antihypertensive Agents; Aspirin; Chronic Disease; Female; Humans; Hypertension; Pregnancy; P

1994
Practical questions about therapy of hypertension with ACE inhibitors. J. Scholze, Berlin, on the 24-hour effect, possible combinations and side-effects of ACE inhibitors--ASS/antirheumatic agents.
    Fortschritte der Medizin, 1995, Feb-10, Volume: 113, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Int

1995
Stroke prevention.
    Postgraduate medical journal, 1995, Volume: 71, Issue:834

    Topics: Aged; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Dementia, Vascular; Humans; Hypertens

1995
Gender differences in the presentation, treatment, and short-term mortality of acute chest pain.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1994, Volume: 17, Issue:6

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Chest Pain; Coronary Angiography

1994
How Swedish obstetricians manage hypertensive disorders in pregnancy. A questionnaire study.
    Acta obstetricia et gynecologica Scandinavica, 1994, Volume: 73, Issue:8

    Topics: Adult; Antihypertensive Agents; Aspirin; Diuretics; Female; Humans; Hypertension; Pre-Eclampsia; Pre

1994
Diaspirin crosslinked hemoglobin (DCLHb): control of pressor effect with anti-hypertensive agents.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3

    Topics: Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Blood Substitutes; Hemoglobins; Hypertens

1994
Aspirin in pregnancy.
    Lancet (London, England), 1993, Mar-20, Volume: 341, Issue:8847

    Topics: Aspirin; Female; Fetal Growth Retardation; Humans; Hypertension; Parity; Pregnancy; Pregnancy Compli

1993
Aspirin in pregnancy.
    Lancet (London, England), 1993, Mar-20, Volume: 341, Issue:8847

    Topics: Aspirin; Bias; Female; Fetal Growth Retardation; Humans; Hypertension; Pregnancy; Pregnancy Complica

1993
Low-dose aspirin in pregnancy: changes in patterns of prescription in The Netherlands.
    European journal of obstetrics, gynecology, and reproductive biology, 1993, Volume: 52, Issue:1

    Topics: Aspirin; Female; Fetal Growth Retardation; Humans; Hypertension; Netherlands; Pre-Eclampsia; Pregnan

1993
Age-dependent modifications of the role of prostanoids in cardiac preparations from normotensive and hypertensive rats.
    Pharmacological research, 1993, Volume: 28, Issue:4

    Topics: Age Factors; Animals; Arachidonic Acid; Aspirin; Heart; Hypertension; In Vitro Techniques; Norepinep

1993
Low dose aspirin in pregnancy: a clinical and biochemical study of effects on the newborn.
    Journal of perinatal medicine, 1993, Volume: 21, Issue:3

    Topics: Aspirin; Birth Weight; Cerebral Hemorrhage; Female; Fetal Blood; Fetal Growth Retardation; Gestation

1993
Effect of aspirin on the contractility of aortic rings in vitro from spontaneously hypertensive rats.
    Artery, 1993, Volume: 20, Issue:3

    Topics: Animals; Aorta, Thoracic; Aspirin; Hypertension; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats

1993
Factors related to intracranial hematoma formation in patients receiving tissue-type plasminogen activator for acute ischemic stroke.
    Stroke, 1994, Volume: 25, Issue:2

    Topics: Adult; Age Factors; Aged; Analysis of Variance; Aspirin; Brain Ischemia; Cerebral Hemorrhage; Female

1994
[Prevention of stroke. Blood pressure lowering changes in life style and diet are highly effective].
    Lakartidningen, 1993, Aug-11, Volume: 90, Issue:32-33

    Topics: Anticoagulants; Aspirin; Carotid Stenosis; Cerebrovascular Disorders; Endarterectomy, Carotid; Feedi

1993
Different effects of aspirin on blood pressure of spontaneously hypertensive rats (SHR) with high and spontaneously low levels of blood pressure.
    British journal of pharmacology, 1993, Volume: 109, Issue:4

    Topics: Animals; Aspirin; Blood Pressure; Hypertension; Male; Prostaglandins; Rats; Rats, Inbred SHR

1993
Effects of low-dose aspirin therapy on plasma levels of polyunsaturated fatty acids: a preliminary investigation.
    American journal of perinatology, 1995, Volume: 12, Issue:5

    Topics: Adult; Aspirin; Fatty Acids, Unsaturated; Female; Humans; Hypertension; Pilot Projects; Pre-Eclampsi

1995
Do patients with epistaxis have drug-induced platelet dysfunction?
    Clinical otolaryngology and allied sciences, 1995, Volume: 20, Issue:5

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arachidoni

1995
Perinatal morbidity in chronic hypertension.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:2

    Topics: Adult; Aspirin; Chronic Disease; Cohort Studies; Female; Fetal Death; Humans; Hypertension; Infant M

1996
[A study of spontaneous nosebleed. Pharmaceuticals contributed probably in every third case].
    Lakartidningen, 1996, May-01, Volume: 93, Issue:18

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspir

1996
[Atrial fibrillation and apoplexy--risks and prevention].
    Nordisk medicin, 1996, Volume: 111, Issue:6

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Controlled Clinical T

1996
A British Cardiac Society survey of the potential for the secondary prevention of coronary disease: ASPIRE (Action on Secondary Prevention through Intervention to Reduce Events).
    Heart (British Cardiac Society), 1996, Volume: 75, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Cardiac Care Facilities; Cardiology; Cholesterol;

1996
Cerebrovascular events in adult patients with cyanotic congenital heart disease.
    Journal of the American College of Cardiology, 1996, Volume: 28, Issue:3

    Topics: Adult; Aged; Anemia, Iron-Deficiency; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebrovascular

1996
Presence and treatment of vascular risk factors in patients with vascular cognitive impairment.
    Archives of neurology, 1997, Volume: 54, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspirin; Cognition Disorders; Dementia; Diabetes Complic

1997
Thrombus and branch retinal vein occlusion.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1997, Volume: 235, Issue:1

    Topics: Aspirin; Calcium Channel Blockers; Fluorescein Angiography; Fundus Oculi; Humans; Hyperlipidemias; H

1997
Effects of polymerization on the hypertensive action of diaspirin cross-linked hemoglobin in rats.
    The Journal of laboratory and clinical medicine, 1997, Volume: 129, Issue:6

    Topics: Analysis of Variance; Animals; Aorta; Aspirin; Blood Pressure; Blood Substitutes; Cardiac Output; Cr

1997
Acetylsalicylic acid (aspirin) test for the diagnosis of renovascular hypertension.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1997, Volume: 20, Issue:3

    Topics: Adult; Aspirin; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renovas

1997
Mobile thromboses of the aortic arch without aortic debris. A transesophageal echocardiographic finding associated with unexplained arterial embolism. The Filiale Echocardiographie de la Société Française de Cardiologie.
    Circulation, 1997, Jul-01, Volume: 96, Issue:1

    Topics: Adult; Aorta, Thoracic; Arteriosclerosis; Aspirin; Blood Coagulation Tests; Diabetes Complications;

1997
Stroke recurrence among 30 days survivors of ischemic stroke in a prospective community-based study.
    Neurological research, 1997, Volume: 19, Issue:4

    Topics: Aged; Angina Pectoris; Aspirin; Brain Ischemia; Cerebrovascular Disorders; Cohort Studies; Female; F

1997
What have we learned from the HOT (Hypertension Optimal Treatment) study?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:10

    Topics: Aspirin; Cardiovascular Diseases; Goals; Humans; Hypertension; Morbidity; Prospective Studies; Rando

1997
Aspirin treatment of the low-dose-endotoxin-treated pregnant rat: pathophysiologic and immunohistologic aspects.
    The Journal of laboratory and clinical medicine, 1997, Volume: 130, Issue:5

    Topics: Albuminuria; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apyrase; Aspirin; Blood Pressure; Cel

1997
Antihypertensive efficacy of angiotensin converting enzyme inhibition and aspirin counteraction.
    Clinical pharmacology and therapeutics, 1998, Volume: 63, Issue:1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypert

1998
Aspirin treatment.
    Journal of advanced nursing, 1998, Volume: 27, Issue:3

    Topics: Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Humans; Hypertension; Patient Education as Top

1998
Secondary prevention in coronary heart disease: baseline survey of provision in general practice.
    BMJ (Clinical research ed.), 1998, May-09, Volume: 316, Issue:7142

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood P

1998
J-curve not burned off by HOT study. Hypertension Optimal Treatment.
    Lancet (London, England), 1998, Jun-13, Volume: 351, Issue:9118

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovas

1998
[Increased blood pressure should be efficiently treated. Results from the Hypertension Optimal Treatment Study (the HOT-study)].
    Ugeskrift for laeger, 1998, Jun-15, Volume: 160, Issue:25

    Topics: Aged; Antihypertensive Agents; Aspirin; Female; Humans; Hypertension; Male; Middle Aged; Multicenter

1998
Risk of stroke in patients with atrial fibrillation.
    The Journal of family practice, 1998, Volume: 47, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Cohort Studies; Dose-

1998
How low should blood pressure go?
    Health news (Waltham, Mass.), 1998, Jul-25, Volume: 4, Issue:9

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Humans; Hypertension

1998
Hypertension Optimal Treatment (HOT) trial.
    Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Humans; Hypertension; Platelet Aggregation Inhibit

1998
Hypertension Optimal Treatment (HOT) trial.
    Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium

1998
I take Adalat (or nifedipine, also sold as Procardia) and captopril tablets daily for my high blood pressure. My physician told me not to take aspirin because of the possibility of drug interactions. From what I have read about aspirin, I hate to miss out
    Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:2

    Topics: Aspirin; Captopril; Drug Interactions; Humans; Hypertension; Nifedipine

1998
Intensive blood pressure lowering warranted. Results of the HOT study: an epitaph for the J-curve concept in hypertension.
    Journal of human hypertension, 1998, Volume: 12, Issue:11

    Topics: Aspirin; Blood Pressure; Cerebrovascular Disorders; Humans; Hypertension; Myocardial Infarction; Pla

1998
Drug therapy before coronary artery surgery: nitrates are independent predictors of mortality and beta-adrenergic blockers predict survival.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:2

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagul

1999
Delayed neurological deterioration following resection of arteriovenous malformations of the brain.
    Journal of neurosurgery, 1999, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Aneurysm; Anticoagulants; Antihypertensive Agents; Asp

1999
Cost effectiveness of intensive treatment of hypertension. Based on presentations by Donald S. Shepard, PhD; and Dominic Hodgkin, PhD.
    The American journal of managed care, 1998, Volume: 4, Issue:12 Suppl

    Topics: Antihypertensive Agents; Aspirin; Cost of Illness; Cost-Benefit Analysis; Humans; Hypertension; Myoc

1998
British Hypertension Society guidelines for hypertension management 1999: summary.
    BMJ (Clinical research ed.), 1999, Sep-04, Volume: 319, Issue:7210

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure Determination; Card

1999
Consultation section. Cataract surgical problem.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:9

    Topics: Aspirin; Cataract; Humans; Hypertension; Male; Middle Aged; Phacoemulsification; Retinal Vein Occlus

1999
Stroke risk, cholesterol and statins.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 1999, Volume: 8, Issue:6

    Topics: Aged; Aspirin; Diabetes Complications; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitor

1999
Safety of labor epidural anesthesia for women with severe hypertensive disease. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:5 Pt 1

    Topics: Adult; Anesthesia, Epidural; Aspirin; Cesarean Section; Chronic Disease; Double-Blind Method; Female

1999
Changes in prostacyclin, thromboxane A2 and F2-isoprostanes, and influence of eicosapentaenoic acid and antiplatelet agents in patients with hypertension and hyperlipidemia.
    Immunopharmacology, 1999, Oct-15, Volume: 44, Issue:1-2

    Topics: Aspirin; Dinoprost; Dipyridamole; Eicosapentaenoic Acid; Epoprostenol; Humans; Hyperlipidemias; Hype

1999
Secular trends in the management of hypertension and atrial fibrillation in patients presenting with stroke.
    QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillatio

2000
Aspirin use and the prevention of acute ischemic cranial nerve palsy.
    American journal of ophthalmology, 2000, Volume: 129, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Cranial Nerve Diseases; Crani

2000
Coronary revascularization and aggressive lipid lowering.
    The Journal of invasive cardiology, 1999, Volume: 11, Issue:2

    Topics: Aspirin; Atorvastatin; Coronary Stenosis; Heptanoic Acids; Humans; Hyperlipidemias; Hypertension; Hy

1999
Effect of aspirin on the contractility of aortic smooth muscle and the course of blood pressure development in male spontaneously hypertensive rats.
    Artery, 1998, Volume: 23, Issue:1

    Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Blood Pressure; Calcium; Calcium Signaling; Cell Membran

1998
[Primary prevention of cardiovascular events by acetylsalicylic acid in patients with hypertension in Spain].
    Medicina clinica, 2000, Apr-01, Volume: 114, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Female; Humans; Hyp

2000
Analysis of risk factors involved in oral-anticoagulant-related intracranial haemorrhages.
    QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Case-Control Studi

2000
Sex differences and similarities in the management and outcome of stroke patients.
    Stroke, 2000, Volume: 31, Issue:8

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cohort Studies; Comorbidity;

2000
The Hypertension Optimal Treatment Study: what did it give us?
    Current hypertension reports, 1999, Volume: 1, Issue:4

    Topics: Aged; Aspirin; Blood Pressure; Diabetic Angiopathies; Fibrinolytic Agents; Humans; Hypertension; Mid

1999
Antiplatelet drugs in cardiovascular prevention: coronary events and stroke: primary prevention.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Aspirin; Carotid Stenosis; Cost-Benefit Analysis; Diabetes Mellitus; Digestive System; Female; Human

2000
Should low-dose aspirin also be a background therapy for all patients with systemic lupus erythematosus (SLE)?
    Lupus, 2000, Volume: 9, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Humans; Hypertension; Lupus Eryt

2000
[Pharmacological prevention of cardiovascular diseases in general practice].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Sep-20, Volume: 120, Issue:22

    Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Benzothiadiazines; Cardiovascular Diseases; Cost-Bene

2000
Effect of long-term exercise training on blood viscosity during endurance exercise at an anaerobic threshold intensity.
    Japanese circulation journal, 2000, Volume: 64, Issue:11

    Topics: Adult; Aged; Anaerobic Threshold; Anticoagulants; Aspirin; Blood Viscosity; Cardiomyopathy, Dilated;

2000
Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people.
    Stroke, 2001, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Cerebral Hemorrhage; Comorbidity; Epileps

2001
Aspirin for primary prevention. Treatment policy should be based on all trial evidence, not subgroup analysis.
    BMJ (Clinical research ed.), 2000, Dec-09, Volume: 321, Issue:7274

    Topics: Aspirin; Clinical Trials as Topic; Humans; Hypertension; Platelet Aggregation Inhibitors; Primary Pr

2000
Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey.
    Diabetes care, 2001, Volume: 24, Issue:2

    Topics: Adult; Albuminuria; Angina Pectoris; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabe

2001
Late normalisation of uterine artery velocimetry in high risk pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 95, Issue:1

    Topics: Arteries; Aspirin; Blood Flow Velocity; Dose-Response Relationship, Drug; Female; Fetal Death; Human

2001
[Platelet aggregation in patients with various forms of left ventricular hypertrophy and its changes at long-term follow-up and treatment].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:11

    Topics: Aspirin; Disease Progression; Echocardiography; Electrocardiography, Ambulatory; Follow-Up Studies;

2000
Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis.
    Circulation, 2001, Apr-10, Volume: 103, Issue:14

    Topics: Aged; Arteriosclerosis; Ascorbic Acid; Aspirin; C-Reactive Protein; Female; Fibrinogen; Humans; Hype

2001
Non-pregnant circulatory volume status predicts subsequent pregnancy outcome in normotensive thrombophilic formerly preeclamptic women.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 95, Issue:2

    Topics: Aspirin; Birth Weight; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; HELLP Syndrome

2001
Characteristics of patients with antiphospholipid syndrome with major bleeding after oral anticoagulant treatment.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antiphospholipid Syndrome; Asp

2001
Edge stenosis after intracoronary radiotherapy: angiographic, intravascular, and histological findings.
    Circulation, 2001, May-01, Volume: 103, Issue:17

    Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Anticoagulants; Aspirin; Brachytherapy; Clopidogrel; Com

2001
[Decreased platelet aggregation during angiotensin-converting enzyme inhibitor therapy. Results of a pilot study].
    Deutsche medizinische Wochenschrift (1946), 2001, Jun-15, Volume: 126, Issue:24

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Case-Control Studies; Coronary Disease; Dru

2001
Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:8

    Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blood Pressure; Consci

2001
The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings.
    Journal of medicine, 2001, Volume: 32, Issue:3-4

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cough; Female; Humans; Hypertension; Male;

2001
Increased platelet glycoprotein V levels in patients with coronary and peripheral atherosclerosis--the influence of aspirin and cigarette smoking.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:3

    Topics: Adenosine Diphosphate; Adult; Aged; Arteriosclerosis; Aspirin; beta-Thromboglobulin; Biomarkers; Cho

2001
[Stroke management in a general internal medicine department: results of a survey regarding practice].
    La Revue de medecine interne, 2001, Volume: 22, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Data Collection; Echocardiography; Ele

2001
Maturation reveals a decrease in endothelium-dependent contraction induced by depolarization in the aorta of spontaneously hypertensive rats.
    Life sciences, 2001, Aug-31, Volume: 69, Issue:15

    Topics: Aging; Animals; Aorta; Aspirin; Biphenyl Compounds; Body Weight; Endothelium, Vascular; Heptanoic Ac

2001
Treatment of cardiac risk factors in diabetic patients: How well do we follow the guidelines?
    American heart journal, 2001, Volume: 142, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Pressure

2001
[Arterial hypertension - the specific case].
    Deutsche medizinische Wochenschrift (1946), 2001, Nov-02, Volume: 126, Issue:44

    Topics: Aspirin; Carotid Artery, Internal; Carotid Stenosis; Diabetes Complications; Diet; Exercise; Follow-

2001
Effects of low-dose aspirin on endothelial function in hypertensive patients.
    Clinical cardiology, 2001, Volume: 24, Issue:11

    Topics: Aged; Aspirin; Blood Volume; Case-Control Studies; Cyclic GMP; Endothelium, Vascular; Female; Humans

2001
[Guidelines for antithrombotic therapy in atrial fibrillation: what the Italian Hemostasis and Thrombosis Society thinks].
    Haematologica, 2001, Volume: 86, Issue:9 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Comorbidity; Diabetes

2001
Acute myocardial infarction in the young--The University of Michigan experience.
    American heart journal, 2002, Volume: 143, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Anticoagulants; Aspirin; Coronary Artery B

2002
Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats.
    Circulation, 2002, Jan-22, Volume: 105, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Aspirin; Culture Techniques; Dose-Respo

2002
Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats.
    Circulation, 2002, Jan-22, Volume: 105, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Aspirin; Culture Techniques; Dose-Respo

2002
Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats.
    Circulation, 2002, Jan-22, Volume: 105, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Aspirin; Culture Techniques; Dose-Respo

2002
Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats.
    Circulation, 2002, Jan-22, Volume: 105, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Aspirin; Culture Techniques; Dose-Respo

2002
[Pulsating exophtalmos and contralateral carotid-cavernous fistula].
    Revue neurologique, 2002, Volume: 158, Issue:5 Pt 1

    Topics: Aged; Aspirin; Blepharoptosis; Carotid-Cavernous Sinus Fistula; Cavernous Sinus Thrombosis; Conjunct

2002
Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells.
    Atherosclerosis, 1979, Volume: 34, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Aspirin; Cell Division; Cells, Cultured; Chloroquine; Diabetes Mel

1979
Vascular responsiveness to pressor agents during human pregnancy.
    The Journal of reproductive medicine, 1979, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna

1979
Dietary prevention of atherosclerosis: new aspects.
    Comprehensive therapy, 1979, Volume: 5, Issue:12

    Topics: Animals; Arteriosclerosis; Aspirin; Cholesterol, Dietary; Diabetes Mellitus; Diet; Heart; Hypertensi

1979
[Role of prostaglandins in blood pressure regulation].
    Kardiologiia, 1977, Volume: 17, Issue:10

    Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Vessels; Diet; Epinephrine; Female; Hyperten

1977
The influence of a linoleic acid-rich diet and of acetyl salicylic acid on NaCl induced hypertension, Na+--and H2O-blance and urinary prostaglandin excretion in rats.
    Acta biologica et medica Germanica, 1978, Volume: 37, Issue:5-6

    Topics: Animals; Aspirin; Body Water; Dietary Fats; Hypertension; Linoleic Acids; Male; Oils; Prostaglandins

1978
Effects of prostaglandin E2 and prostaglandin inhibitors on adrenal regeneration hypertension.
    The American journal of physiology, 1977, Volume: 232, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Aspirin; Female; Hypertension; Indomethacin; Nephrectomy; Pr

1977
[Problems of arteriosclerosis epidemiology. Analysis of risk factors with a view to a possible therapy].
    Minerva medica, 1976, Dec-22, Volume: 67, Issue:62

    Topics: Anti-Inflammatory Agents; Anticoagulants; Antihypertensive Agents; Arteriosclerosis; Aspirin; Blood

1976
Salt-induced hypertension in rats with hereditary hydronephrosis: the effect of renomedullary transplantation.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:2

    Topics: Animals; Aspirin; Blood Pressure; Blood Volume Determination; Extracellular Space; Hydronephrosis; H

1976
Prevention of stroke.
    Postgraduate medicine, 1975, Volume: 57, Issue:2

    Topics: Age Factors; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Auscultation; Cerebral Angiograph

1975
Analgesic abuse in urological practice.
    The British journal of surgery, 1975, Volume: 62, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Anemia; Aspirin; Codeine; Female; Humans; Hypertension; Kidney Cal

1975
[The use of acetylsalicylic acid as a platelet antiaggregant].
    Arquivos brasileiros de cardiologia, 1992, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Drug Evaluation; Heart Diseases; Hemostasis; Humans; Hypert

1992
Influence of mild to moderate treated hypertension on 9-11 year mortality in patients with pre-existing coronary heart disease.
    Journal of human hypertension, 1992, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Cohort Studies; Coronary Disease; Female; Humans; Hyper

1992
Effect of aspirin on the contractility of aortic smooth muscle in female spontaneously hypertensive rats.
    Artery, 1992, Volume: 19, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Aorta; Aspirin; Blood Pressure; Clonidine; Female; Hypertension;

1992
Quadruplet pregnancy: contemporary management and outcome.
    Obstetrics and gynecology, 1992, Volume: 80, Issue:3 Pt 1

    Topics: Adult; Aspirin; Bed Rest; Female; Humans; Hypertension; Infant, Newborn; Monitoring, Physiologic; Pr

1992
Anti-platelet therapy in diabetic and non-diabetic progressive renal failure.
    Clinical nephrology, 1992, Volume: 37, Issue:1

    Topics: Aspirin; Blood Pressure; Creatinine; Diabetic Nephropathies; Dipyridamole; Docosahexaenoic Acids; Dr

1992
[Cardiovascular risk factors and restenosis after PTCA].
    Zeitschrift fur Kardiologie, 1992, Volume: 81, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Coronary Angiography; Coro

1992
Low-dose aspirin and vascular response in pregnant patients sensitive to angiotensin II.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1991, Volume: 35, Issue:2

    Topics: Angiotensin II; Aspirin; Blood Pressure; Drug Interactions; Female; Humans; Hypertension; Pregnancy;

1991
Low-dose aspirin and nulliparae.
    Lancet (London, England), 1991, Oct-05, Volume: 338, Issue:8771

    Topics: Aspirin; Female; Humans; Hypertension; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pr

1991
Ischemic stroke. How to keep the first one from happening.
    Postgraduate medicine, 1991, Volume: 90, Issue:8

    Topics: Aspirin; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypertension; I

1991
Horner's syndrome secondary to spontaneous carotid dissection with normal angiographic findings.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:11

    Topics: Angiography, Digital Subtraction; Aortic Dissection; Aspirin; Blood Pressure; Carotid Artery Disease

1991
Aspirin test for differentiation of unilateral renovascular hypertension from hyperreninemic essential hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:9

    Topics: Adult; Aged; Aspirin; Blood Pressure; Diagnosis, Differential; Dinoprostone; Female; Humans; Hyperte

1991
Prophylactic aspirin treatment: the merits of timing. International Womb-to-Tomb Chronome Study Group.
    JAMA, 1991, Dec-11, Volume: 266, Issue:22

    Topics: Aspirin; Circadian Rhythm; Female; Humans; Hypertension; Myocardial Infarction; Pilot Projects; Preg

1991
Thromboxane A2 synthesis in pregnancy-induced hypertension.
    Lancet (London, England), 1990, Mar-31, Volume: 335, Issue:8692

    Topics: Adolescent; Adult; Aspirin; Evaluation Studies as Topic; Female; Humans; Hypertension; Platelet Acti

1990
An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987)
    The New England journal of medicine, 1991, Jan-17, Volume: 324, Issue:3

    Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Female; Humans; Hyp

1991
Treatment of severe pre-eclampsia by acetyl salicylic acid.
    Asia-Oceania journal of obstetrics and gynaecology, 1991, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Albuminuria; Aspirin; Blood Pressure; Body Temperature; Edema; Female; Humans; Hy

1991
[Aspirin and pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1990, Jun-09, Volume: 134, Issue:23

    Topics: Aspirin; Blood Coagulation Factors; Female; Fetal Death; Fetal Growth Retardation; Humans; Hypertens

1990
Chronobiologic approach to pregnancy-induced hypertension and individualized assessment of low-dose aspirin for pre-eclampsia prevention.
    Progress in clinical and biological research, 1990, Volume: 341A

    Topics: Adult; Aspirin; Blood Pressure; Chronobiology Phenomena; Female; Heart Rate; Humans; Hypertension; P

1990
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:6 Pt 1

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Analysis of Variance; Angiotensin II; Aspirin; Bloo

1990
Nasal polyposis as a risk factor for hypertension.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1990, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Asthma; C

1990
Aspirin to prevent pregnancy-induced hypertension.
    The New England journal of medicine, 1990, Jan-18, Volume: 322, Issue:3

    Topics: Aspirin; Female; Hemostasis; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascula

1990
Prolongation of premature gestation in women with hemolysis, elevated liver enzymes and low platelets. A report of five cases.
    The Journal of reproductive medicine, 1990, Volume: 35, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Female; Hemolysis; Humans; Hypertension; Liver; Pregnancy;

1990
Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.
    Circulation, 1990, Volume: 81, Issue:6

    Topics: Acetylcholine; Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Female; Forea

1990
Myocardial infarction. Primary prevention.
    The Practitioner, 1990, Feb-22, Volume: 234, Issue:1483

    Topics: Adult; Aspirin; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial In

1990
Increased platelet aggregation and intracellular calcium in hypertensive patients: effects of cyclo-oxygenase blockade.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcium

1989
[Prevention of complications of severe arterial hypertension in pregnancy using platelet antiaggregants].
    Presse medicale (Paris, France : 1983), 1989, Apr-15, Volume: 18, Issue:15

    Topics: Adult; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Humans; Hypertension; Pregnancy; Pr

1989
Endothelin-induced sudden death and the possible involvement of platelet activating factor (PAF).
    Life sciences, 1989, Volume: 45, Issue:20

    Topics: Animals; Aspirin; Azepines; Blood Pressure; Death, Sudden; Dexamethasone; Diltiazem; Electrocardiogr

1989
Clinical trials on the efficacy of pharmacologic intervention reducing mortality from cardiovascular diseases.
    Cardiology, 1985, Volume: 72, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Clofibrate;

1985
Low-dose aspirin in pregnancy.
    Lancet (London, England), 1988, Feb-20, Volume: 1, Issue:8582

    Topics: Aspirin; Female; Fetal Growth Retardation; Humans; Hypertension; Infant, Newborn; Lupus Erythematosu

1988
Clinical trial with muzolimine in healthy and hypertensive subjects: new vistas on the drug action.
    International journal of clinical pharmacology research, 1987, Volume: 7, Issue:6

    Topics: Aged; Aspirin; Dinoprostone; Drug Therapy, Combination; Humans; Hypertension; Lysine; Middle Aged; M

1987
Preeclampsia: platelets and antiplatelet therapy.
    Hospital practice (Office ed.), 1988, May-30, Volume: 23, Issue:5A

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Diagnosis, Differential; Female; Fetus; Humans; Hyperte

1988
Low-dose aspirin. I. Effect on angiotensin II pressor responses and blood prostaglandin concentrations in pregnant women sensitive to angiotensin II.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:5

    Topics: Angiotensin II; Aspirin; Blood Pressure; Drug Administration Schedule; Drug Resistance; Female; Huma

1988
Aspirin enhances the antihypertensive effect of captopril in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:3

    Topics: Animals; Aspirin; Blood Pressure; Captopril; Diuresis; Drinking; Drug Synergism; Electrolytes; Hyper

1987
Failure of chronic aspirin treatment to inhibit urinary prostaglandin excretion in spontaneously hypertensive rats: comparison with indomethacin and flurbiprofen.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3

    Topics: Animals; Aspirin; Drug Administration Schedule; Flurbiprofen; Hypertension; Indomethacin; Kidney; Ma

1987
Prevention of cardiovascular disease. Of what value are risk factor modification, exercise, fish consumption, and aspirin therapy?
    Postgraduate medicine, 1987, Volume: 81, Issue:5

    Topics: Animals; Aspirin; Cardiovascular Diseases; Feeding Behavior; Fish Products; Humans; Hyperlipidemias;

1987
Platelet function in pregnancy induced hypertension following treatment with labetalol and low dose aspirin.
    Thrombosis research, 1987, May-15, Volume: 46, Issue:4

    Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug;

1987
Different modes of interaction of bradykinin with prostaglandins in pain and acute inflammation.
    Advances in experimental medicine and biology, 1986, Volume: 198 Pt B

    Topics: Animals; Aspirin; Blood Pressure; Bradykinin; Bromelains; Dogs; Hypertension; Inflammation; Pain; Pr

1986
Evidence that the rat is not an appropriate model to study the role of prostaglandins in normal or abnormal platelet aggregation.
    Thrombosis research, 1986, Feb-15, Volume: 41, Issue:4

    Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Blood Pressure; Disease Models, Animal; Ep

1986
Atrioventricular conduction block caused by phenylpropanolamine.
    JAMA, 1985, May-10, Volume: 253, Issue:18

    Topics: Adolescent; Aspirin; Chlorpheniramine; Drug Combinations; Female; Heart Block; Humans; Hypertension;

1985
The effects on lipids, blood viscosity and platelet aggregation of combined use of niceritrol (Perycit) and a low dose of acetylsalicylic acid.
    Atherosclerosis, 1985, Volume: 55, Issue:1

    Topics: Adult; Aged; Arteriosclerosis; Aspirin; Blood Viscosity; Diabetes Mellitus; Female; Fibrinogen; Huma

1985
Peripheral vascular disease: treatment and referral of the elderly. Part II.
    Geriatrics, 1985, Volume: 40, Issue:7

    Topics: Aged; Arterial Occlusive Diseases; Aspirin; Brain Ischemia; Carotid Artery Diseases; Cerebrovascular

1985
Drugs which inhibit prostaglandin biosynthesis.
    Pharmacological reviews, 1974, Volume: 26, Issue:1

    Topics: Acetaminophen; Antioxidants; Arachidonic Acids; Aspirin; Blood Platelets; Dronabinol; Fatty Acids; H

1974
[Qualitative changes in prostaglandins in kidneys of normotonic and hypertonic animals under the effect of aspirin-like preparations].
    Eksperimentalna meditsina i morfologiia, 1972, Volume: 11, Issue:3

    Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Hypertension; Indomethacin; Prostaglandins; Rats;

1972
The effect of some drugs on oxalic acid excretion in urine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:2

    Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes

1970
Analgesic nephropathy.
    The New Zealand medical journal, 1974, Jun-26, Volume: 79, Issue:518

    Topics: Adult; Aged; Analgesics; Anemia; Aspirin; Codeine; Drug Combinations; Female; Follow-Up Studies; Hum

1974
Epistaxis. A clinical study with special reference to fibrinolysis.
    Acta oto-laryngologica. Supplementum, 1974, Volume: 317

    Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Aspirin; Child; Cyclohexanecarboxylic Acids; Epistaxis

1974
Influence of some drugs on platelet aggregation: a study in hypertensive patients.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 52

    Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Blood Cell Count; Blood

1972
Stroke: malignant and benign syndromes.
    Southern medical journal, 1973, Volume: 66, Issue:8

    Topics: Anticoagulants; Aspirin; Carotid Artery Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; De

1973
Transient ischemic attack: an early warning system for stroke?
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Aged; Angiography; Anticoagulants; Aspirin; Blood Pressure; Brain Edema; Cerebrovascular Disorders;

1973
[The action of arachidonic acid on experimental arterial hypertension in the rat].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1973, Volume: 14, Issue:6

    Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Corticosterone; Drug Antagonism; Hypertension;

1973
Drug-induced nephropathies.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Animals; Arthritis, Rheumatoid; Aspirin; Colic; Complement System Proteins; Glomerular Filtration Ra

1973
Modification of the effects of hypertension on lysosomes and connective tissue in the rat aorta.
    Circulation research, 1974, Volume: 34, Issue:2

    Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aspirin; Connective Tissue; DN

1974
Treatment of stroke: medical or surgical?
    Geriatrics, 1974, Volume: 29, Issue:3

    Topics: Angiography; Antihypertensive Agents; Aspirin; Blood Pressure; Carotid Arteries; Carotid Artery Thro

1974
Regular aspirin intake and acute myocardial infarction.
    British medical journal, 1974, Mar-09, Volume: 1, Issue:5905

    Topics: Adult; Age Factors; Aged; Arthritis; Aspirin; Diabetes Mellitus; Female; Humans; Hypertension; Male;

1974
Heterocyclic systems with a bridgehead nitrogen. II. 6-Chloroimidazo[2,1-b]thiazole and some of its 5-substituted derivatives.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:6

    Topics: Animals; Aspirin; Blood Pressure; Chemical Phenomena; Chemistry; Enterobacteriaceae; Female; Fungi;

1969
Management of epistaxis by controlled hypotension.
    The Laryngoscope, 1968, Volume: 78, Issue:11

    Topics: Ascorbic Acid; Aspirin; Epistaxis; Humans; Hypertension; Hypnotics and Sedatives; Hypotension, Contr

1968