aspirin has been researched along with Blood Loss, Surgical in 245 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Blood Loss, Surgical: Loss of blood during a surgical procedure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aim to investigate the safety profile of aspirin continuation in the perioperative period in patients undergoing elective primary inguinal hernia repair." | 7.83 | Is preoperative withdrawal of aspirin necessary in patients undergoing elective inguinal hernia repair? ( Lomanto, D; Ong, W; Shen, T; Tan, WB, 2016) |
| "Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase activity, resulting in altered platelet function and thus potentially enhanced bleeding." | 7.69 | Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients. ( Lawrence, C; Sakuntabhai, A; Tiling-Grosse, S, 1994) |
| "Aspirin-treated patients with coronary artery disease were randomly assigned to either prasugrel 10 mg or clopidogrel 75 mg daily for 7 days." | 6.77 | Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial. ( Angiolillo, DJ; Baker, BA; Heiselman, DE; Jakubowski, JA; Li, W; Logan, DK; Price, MJ; Walder, JS; Winters, KJ, 2012) |
| "In laparoscopic surgery for colorectal cancer (CRC) for patients who receive antiplatelet therapy (APT), it remains unclear whether APT should be continued or temporarily withdrawn." | 5.62 | Impact of perioperative aspirin continuation on bleeding complications in laparoscopic colorectal cancer surgery: a propensity score-matched analysis. ( Fujikawa, T; Takahashi, R, 2021) |
| "Aspirin was not associated with a significantly higher risk of hidden blood loss (aspirin group; median 598 mL [410-783 mL] vs control group; median 556 ml [321-741 mL], p = 0." | 5.62 | Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss. ( Ito, Y; Kanazawa, T; Ohmori, T; Tada, K; Toda, K; Yagata, Y, 2021) |
| "The topic of aspirin (acetylsalicylic acid, ASA) use in coronary artery disease patients planned for coronary artery bypass grafting during perioperative period is among the most disputed issues in cardiac surgery." | 5.27 | Effect of Sustained Use of Aspirin until the Time of Surgery on Outcomes following Coronary Artery Bypass Grafting: A Randomized Clinical Trial. ( Ghandi, Y; Kamali, A; Sharifi, M, 2018) |
| " The use of tranexamic acid to control surgical bleeding and aspirin for venous thromboembolism prophylaxis has gained popularity." | 5.22 | Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial. ( Barksdale, LC; Calvo, C; McNamara, CA; Patel, PD; Suarez, JC; Szubski, CR, 2016) |
| "A subset of the TRITON-TIMI 38 study (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis In Myocardial Infarction 38), in which patients with acute coronary syndrome were randomized to treatment with aspirin and either clopidogrel or prasugrel, underwent isolated CABG (N = 346)." | 5.16 | Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis. ( Goodnough, LT; Lenarz, LA; Levy, JH; Poston, RS; Short, MA; Smith, PK; Weerakkody, GJ, 2012) |
| " As the indications for clopidogrel expand, an increasing number of patients undergoing off-pump coronary artery bypass surgery (OPCAB) are also undergoing dual antiplatelet therapy (DAPT), with its higher risk of bleeding complications." | 5.15 | Effect of hydroxyethyl starch 130/0.4 on blood loss and coagulation in patients with recent exposure to dual antiplatelet therapy undergoing off-pump coronary artery bypass graft surgery. ( Ahn, SW; Kwak, YL; Lee, JS; Shim, JK; Song, JW; Yoo, KJ, 2011) |
| "In an analysis of the Melagatran Thrombosis Prophylaxis in Orthopedic Surgery (METHRO) III study, we evaluated whether concomitant administration of aspirin (ASA) and non-steroidal anti-inflammatory drugs (NSAIDs) with the direct thrombin inhibitor melagatran/ximelagatran or the low-molecular-weight heparin enoxaparin increased bleeding in patients undergoing major joint surgery." | 5.12 | Assessment of bleeding after concomitant administration of antiplatelet and anticoagulant agents in lower limb arthroplasty. ( Agnelli, G; Andersson, M; Bylock, A; Cohen, AT; Dahl, OE; Eriksson, BI; Mouret, P; Ogren, M; Panfilov, S; Rosencher, N, 2006) |
| "Patients with heart disease are frequently maintained on a regimen of aspirin because of its ability to decrease thrombotic complications and reduce the prevalence of unstable angina and myocardial infarction." | 5.07 | Aprotinin significantly decreases bleeding and transfusion requirements in patients receiving aspirin and undergoing cardiac operations. ( Guiraudon, GM; Lux, J; McKenzie, FN; Menkis, AH; Murkin, JM; Novick, RJ; Shannon, NA, 1994) |
| "One thousand four hundred forty-two geriatric (ages 60-105 years) patients undergoing isolated primary intramedullary fixation of nonpathologic extracapsular hip fractures from 2009 to 2018 including 657 taking an antiplatelet drug alone (including aspirin), 99 taking warfarin alone, 37 taking a direct oral anticoagulant (DOAC) alone, 59 taking an antiplatelet drug and an anticoagulant, and 590 taking neither." | 4.31 | Full Reversal of Anticoagulants Before Cephalomedullary Fixation of Geriatric Hip Fractures May Not Be Necessary. ( Ahn, J; Hake, ME; Maturana, C; Perdue, AM; Schaffer, NE; Singh, M, 2023) |
| "Acetylsalicylic acid (ASA, aspirin) is a medication widely used for primary and secondary prevention of cardiovascular diseases, which are the leading cause of morbidity and mortality worldwide." | 3.91 | Aspirin for patients undergoing major lung resections: hazardous or harmless?†. ( Messerschmidt, A; Schneider, T; Stamenovic, D, 2019) |
| "Aspirin and unfractionated heparin (UH) are accepted options for venous thromboembolism (VTE) prophylaxis after total joint arthroplasty (TJA)." | 3.88 | The Role of Aspirin and Unfractionated Heparin Combination Therapy Immediately After Total Hip and Knee Arthroplasty. ( Karadsheh, MS; Koueiter, DM; Mells, A; Siljander, MP; Sobh, AH, 2018) |
| "We aim to investigate the safety profile of aspirin continuation in the perioperative period in patients undergoing elective primary inguinal hernia repair." | 3.83 | Is preoperative withdrawal of aspirin necessary in patients undergoing elective inguinal hernia repair? ( Lomanto, D; Ong, W; Shen, T; Tan, WB, 2016) |
| " Among 614 participants with a preoperative diagnosis of coronary artery disease (CAD), in-hospital aspirin use was significantly higher in the contemporary period (66% vs 30." | 3.83 | Perioperative antiplatelet therapy and cardiovascular outcomes in patients undergoing joint and spine surgery. ( Berger, JS; Errico, T; Iorio, R; Nukala, S; Oberweis, BS; Radford, MJ; Rosenberg, A; Smilowitz, NR; Stuchin, S, 2016) |
| "Dual antiplatelet therapy with combined aspirin and clopidogrel as well as clopidogrel is associated with an increased incidence of perioperative wound hematoma compared to aspirin but on an acceptable low level of incidence." | 3.78 | Risk of wound hematoma at carotid endarterectomy under dual antiplatelet therapy. ( Goertler, M; Halloul, Z; Heinze, HJ; Meyer, F; Oldag, A; Schreiber, S; Weber, M, 2012) |
| "An increasing number of patients suffering from cardiovascular disease, especially coronary artery disease (CAD), are treated with aspirin and/or clopidogrel for the prevention of major adverse events." | 3.77 | Peri-operative management of antiplatelet therapy in patients with coronary artery disease: joint position paper by members of the working group on Perioperative Haemostasis of the Society on Thrombosis and Haemostasis Research (GTH), the working group on ( Cattaneo, M; Chassot, PG; Eichinger, S; Hofmann, N; Huber, K; Korte, W; Rickli, H; Spannagl, M; Verheugt, F; von Heymann, C; Ziegler, B, 2011) |
| "The majority of surgeons do not stop warfarin or aspirin prior to glaucoma surgery." | 3.74 | Anticoagulation therapy in glaucoma surgery. ( Alwitry, A; King, AJ; Vernon, SA, 2008) |
| "Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase activity, resulting in altered platelet function and thus potentially enhanced bleeding." | 3.69 | Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients. ( Lawrence, C; Sakuntabhai, A; Tiling-Grosse, S, 1994) |
| "And the postoperative hemorrhage and allogenic blood transfusion condition were observed and evaluated." | 2.87 | Preoperative antiplatelet drugs on the hemorrhage and allogenic blood transfusion condition after coronary artery bypass graft surgery. ( Chen, Y; Song, B; Wang, H; Zhu, P, 2018) |
| "Aspirin-treated patients with coronary artery disease were randomly assigned to either prasugrel 10 mg or clopidogrel 75 mg daily for 7 days." | 2.77 | Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial. ( Angiolillo, DJ; Baker, BA; Heiselman, DE; Jakubowski, JA; Li, W; Logan, DK; Price, MJ; Walder, JS; Winters, KJ, 2012) |
| "Treatment with aspirin resulted in a 7." | 2.75 | To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial. ( Darvish, B; Eintrei, C; Fredrikson, M; Gupta, A; Järhult, J; Krook, H; Nyström, M; Oscarsson, A; Pettersson, E; Swahn, E, 2010) |
| "Aspirin pretreatment revealed no beneficial effects and resulted in increased postoperative bleeding and requirement for blood product transfusions after coronary artery bypass grafting in patients with stable angina." | 2.71 | Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism. ( Bochenek, A; Cisowski, M; Dropinski, J; Morawski, W; Sanak, M; Szczeklik, M; Szczeklik, W; Ulczok, R; Waclawczyk, T, 2005) |
| "As Aspirin (ASA) has proven efficacy in preventing patients with CAD from complications related to cardiovascular diseases, most patients scheduled for CABG are treated with ASA therapy." | 2.69 | Aprotinin counterbalances an increased risk of peri-operative hemorrhage in CABG patients pre-treated with Aspirin. ( Beckmann, H; Dauben, HP; Elert, O; Gams, E; Keith, PR; Klein, M; Mayer, G; Schulte, HD, 1998) |
| "In aspirin-treated platelets, the aggregation capacity induced by adenosine diphosphate was inhibited before the operation (p < 0." | 2.68 | Hemostatic function of aspirin-treated platelets vulnerable to cardiopulmonary bypass. Altered shear-induced pathway. ( Eijsman, L; Huet, RC; Sturk, A; Tabuchi, N; Wildevuur, CR, 1995) |
| "Q-wave myocardial infarctions were increased in the aprotinin subgroups (17." | 2.67 | Aprotinin therapy for reoperative myocardial revascularization: a placebo-controlled study. ( Cosgrove, DM; Golding, LA; Heric, B; Loop, FD; Lytle, BW; McCarthy, PM; Novoa, R; Stewart, RW; Taylor, PC, 1992) |
| "Aspirin has an established benefit in reducing the incidence of coronary events and vein graft occlusion." | 2.67 | Pre-operative aspirin decreases platelet aggregation and increases post-operative blood loss--a prospective, randomised, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina. ( Bevan, DH; Cowans, D; Kallis, P; Talbot, S; Tooze, JA; Treasure, T, 1994) |
| "Tranexamic acid is a safe and effective treatment modality, and consideration should be given to use multiple doses and combine different modes of administration." | 2.66 | Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2). ( Mastel, MS; van der Merwe, JM, 2020) |
| " There are doubts in emergency operations, especially in transplant patients, concerning dosage and change in medication." | 2.40 | [Does treatment with thrombocyte aggregation inhibitors modify kidney transplantation surgery?]. ( Klemm, A; Schubert, J; Werner, W; Wunderlich, H, 1998) |
| " A survey of the currently available blood conservation techniques reveals 5 that stand out as reliable methods: 1) high-dose aprotinin therapy, 2) preoperative erythropoietin therapy when time permits adequate dosage before operation, 3) hemodilution by harvest of whole blood immediately before cardiopulmonary bypass, 4) autologous predonation of blood, and 5) salvage of oxygenator blood after cardiopulmonary bypass." | 2.39 | Limiting excessive postoperative blood transfusion after cardiac procedures. A review. ( Ferraris, SP; Ferraris, VA, 1995) |
| "Aspirin was not associated with a significantly higher risk of hidden blood loss (aspirin group; median 598 mL [410-783 mL] vs control group; median 556 ml [321-741 mL], p = 0." | 1.62 | Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss. ( Ito, Y; Kanazawa, T; Ohmori, T; Tada, K; Toda, K; Yagata, Y, 2021) |
| "In laparoscopic surgery for colorectal cancer (CRC) for patients who receive antiplatelet therapy (APT), it remains unclear whether APT should be continued or temporarily withdrawn." | 1.62 | Impact of perioperative aspirin continuation on bleeding complications in laparoscopic colorectal cancer surgery: a propensity score-matched analysis. ( Fujikawa, T; Takahashi, R, 2021) |
| "Aspirin therapy was not associated with a statistically significant or clinically meaningful increase in intraoperative blood loss (2." | 1.48 | Association of Continued Preoperative Aspirin Use and Bleeding Complications in Patients Undergoing Thyroid Surgery. ( Barton, BM; Friedlander, PL; Kandil, E; Raggio, BS, 2018) |
| "Aspirin users were significantly older (P < 0." | 1.46 | Safety and feasibility of liver resection with continued antiplatelet therapy using aspirin. ( Hioki, M; Monden, K; Ohno, S; Ono, K; Sadamori, H; Sakaguchi, K; Saneto, H; Takakura, N; Ueki, T; Yabushita, K, 2017) |
| " The purpose of this study was to compare the efficacy and safety of clopidogrel combined with aspirin (CA) versus sarpogrelate combined with aspirin (SA) treatment in carotid endarterectomy (CEA) patients." | 1.43 | Effects of Sarpogrelate Combined with Aspirin in Patients Undergoing Carotid Endarterectomy in China: A Single-Center Retrospective Study. ( Gu, Y; Guo, J; Guo, L; Qi, L; Tong, Z; Wang, Z; Yu, H; Zhang, J, 2016) |
| "The incidence of symptomatic deep vein thrombosis and pulmonary embolism was evaluated." | 1.43 | Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis. ( Chen, AF; Heller, S; Parvizi, J; Secrist, E; Shahi, A, 2016) |
| "PCNL is safe in patients continuing aspirin perioperatively and does not result in more blood transfusions, angioembolization procedures, or complications." | 1.40 | Continuing aspirin therapy during percutaneous nephrolithotomy: unsafe or under-utilized? ( Elsamra, SE; Hoenig, DM; Leavitt, DA; Moreira, DM; Okeke, Z; Smith, AD; Theckumparampil, N; Waingankar, N, 2014) |
| "Because NSAID use also increases surgical blood loss, proper interval from discontinuation to surgery must be granted to minimize the risk." | 1.40 | Comparison of blood loss according to use of aspirin in lumbar fusion patients. ( Kwon, KY; Park, HJ; Woo, JH, 2014) |
| "Clopidogrel and ticlopidine, sometimes in combination with ASA, are associated with a low risk of bleeding during renal transplantation and does not seem to be a contraindication for renal transplant surgery." | 1.40 | Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study. ( Abramowicz, D; Benahmed, A; Broeders, N; Donckier, V; Ghisdal, L; Hoang, AD; Kianda, M; Le Moine, A; Lemy, A; Madhoun, P; Massart, A; Mikhalski, D; Racapé, J; Sadis, C; Wissing, M, 2014) |
| " These data suggest that continuation of aspirin is safe and that the continuation of aspirin should be considered acceptable and preferable, particularly in patients with perceived substantial medical need for treatment with antiplatelet therapy." | 1.40 | Safety of perioperative aspirin therapy in pancreatic operations. ( Gabale, SD; Irizarry, AM; Kennedy, EP; Lavu, H; McIntyre, CA; Pucci, MJ; Rosato, EL; Winter, JM; Wolf, AM; Yeo, CJ, 2014) |
| "Aspirin was not associated with a significant hemoglobin level variation (median decrease, 2." | 1.38 | Radical prostatectomy with robot-assisted radical prostatectomy and laparoscopic radical prostatectomy under low-dose aspirin does not significantly increase blood loss. ( Armand, C; Binhas, M; Marty, J; Plaud, B; Roudot-Thoraval, F; Salomon, L, 2012) |
| "The aspirin-treated group was significantly older, with higher weight and poorer health state (higher incidence of ischemic heart disease, cerebral ischemia and diabetes)." | 1.38 | [Low-dose aspirin doesn't increase surgical bleeding nor transfusion rate in total knee arthroplasty]. ( Bisbe Vives, E; Castillo Monsegur, J; López Bosque, R; Ruiz, A; Santiveri Papiol, X, 2012) |
| "Aspirin (ASA) has been shown to reduce postoperative coronary artery bypass grafting (CABG) mortality and ischemic events; however, the timing of chronic ASA discontinuation before surgery is controversial because of concern about postoperative bleeding." | 1.37 | Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in coronary artery bypass surgery. ( Blackstone, E; Cho, L; Jacob, M; Smedira, N; Williams, S, 2011) |
| "Surgical blood loss was measured, and the groups were compared for statistically significant differences in blood loss." | 1.35 | The effect of platelet-altering medications on bleeding from minor oral surgery procedures. ( Alvarado, F; Campbell, JH; Partridge, CG, 2008) |
| "Aspirin was associated with a significantly higher risk of hyphaema (P=0." | 1.34 | The effect of aspirin and warfarin therapy in trabeculectomy. ( Chadha, V; Chakrabarti, S; Cobb, CJ; Sanders, R, 2007) |
| "Congenital factor V deficiency is an uncommon bleeding disorder that necessitates hemostatic correction before surgery." | 1.33 | Off-pump coronary artery bypass grafting in a patient with congenital factor V deficiency: report of a case. ( Iguro, Y; Kinjo, T; Masuda, H; Sakata, R; Toyokawa, K; Yotsumoto, G, 2005) |
| "Aspirin was not stopped for a single patient." | 1.33 | Minor oral surgery without stopping daily low-dose aspirin therapy: a study of 51 patients. ( Madan, AD; Madan, G; Madan, GA; Madan, SG, 2005) |
| "The aspirin-treated group received an average of 0." | 1.32 | Aspirin therapy and bleeding during proximal femoral fracture surgery. ( Anekstein, Y; Halperin, N; Mirovsky, Y; Tamir, E, 2004) |
| " BC2 extended aPTT to a maximum of 60 to 80 seconds at 100 to 1000 nmol/L in vitro (rat and human plasma, respectively) and ex vivo (rat) after dosing of rats up to 6 mg/kg in vivo." | 1.30 | Antithrombotic efficacy of a novel murine antihuman factor IX antibody in rats. ( Baker, A; Blackburn, MN; Bugelski, P; Church, WR; Feuerstein, GZ; Koster, P; Nichols, AJ; Patel, A; Toomey, JR; Valocik, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.22) | 18.7374 |
| 1990's | 62 (25.31) | 18.2507 |
| 2000's | 55 (22.45) | 29.6817 |
| 2010's | 113 (46.12) | 24.3611 |
| 2020's | 12 (4.90) | 2.80 |
| Authors | Studies |
|---|---|
| Delto, JC | 1 |
| Fleishman, A | 1 |
| Chang, P | 2 |
| Jiang, DD | 1 |
| Hyde, S | 1 |
| McAnally, K | 1 |
| Crociani, C | 1 |
| Jamil, M | 1 |
| Patel, HD | 1 |
| Pavlinec, J | 1 |
| Budzyn, J | 1 |
| Durant, A | 1 |
| Eilender, B | 1 |
| Gordon, AO | 1 |
| Huang, MM | 1 |
| Pierorazio, PM | 1 |
| Raman, JD | 1 |
| Rogers, C | 1 |
| Su, LM | 1 |
| Wagner, AA | 2 |
| Furrer, MA | 1 |
| Abgottspon, J | 1 |
| Huber, M | 1 |
| Engel, D | 1 |
| Löffel, LM | 1 |
| Beilstein, CM | 1 |
| Burkhard, FC | 1 |
| Wuethrich, PY | 1 |
| Li, Z | 1 |
| Xiang, S | 1 |
| Du, Y | 1 |
| Zhang, M | 1 |
| Bian, Y | 1 |
| Feng, B | 1 |
| Weng, X | 1 |
| Chen, Q | 1 |
| Liu, Y | 2 |
| Ji, Y | 1 |
| Ye, X | 1 |
| Li, X | 1 |
| Fu, Y | 1 |
| Miao, J | 1 |
| Hou, S | 1 |
| Hu, B | 1 |
| Maturana, C | 1 |
| Singh, M | 1 |
| Perdue, AM | 1 |
| Ahn, J | 1 |
| Hake, ME | 1 |
| Schaffer, NE | 1 |
| Qiu, J | 1 |
| Sun, X | 1 |
| Zhang, W | 1 |
| Ke, X | 1 |
| Yang, G | 1 |
| Zhang, L | 1 |
| Won, D | 1 |
| Kim, JS | 1 |
| Ji, JS | 1 |
| Kim, BW | 1 |
| Choi, H | 1 |
| van der Merwe, JM | 1 |
| Mastel, MS | 1 |
| Takahashi, R | 1 |
| Fujikawa, T | 4 |
| Moroi, MK | 1 |
| Loloi, J | 1 |
| Songdej, N | 1 |
| Ashkenazi, I | 1 |
| Schermann, H | 1 |
| Gold, A | 1 |
| Gurel, R | 1 |
| Chechik, O | 3 |
| Warschawski, Y | 1 |
| Schwarzkopf, R | 1 |
| Snir, N | 1 |
| Ohmori, T | 1 |
| Toda, K | 1 |
| Kanazawa, T | 1 |
| Tada, K | 1 |
| Yagata, Y | 1 |
| Ito, Y | 1 |
| Columbo, JA | 1 |
| Lambour, AJ | 1 |
| Sundling, RA | 1 |
| Chauhan, NB | 1 |
| Bessen, SY | 1 |
| Linshaw, DL | 1 |
| Kang, R | 1 |
| Riblet, NBV | 1 |
| Goodney, PP | 1 |
| Stone, DH | 1 |
| Monden, K | 1 |
| Sadamori, H | 1 |
| Hioki, M | 1 |
| Ohno, S | 1 |
| Saneto, H | 1 |
| Ueki, T | 1 |
| Yabushita, K | 1 |
| Ono, K | 2 |
| Sakaguchi, K | 1 |
| Takakura, N | 1 |
| Buhatem Medeiros, F | 1 |
| Pepe Medeiros de Rezende, N | 1 |
| Bertoldi Franco, J | 1 |
| Porrio de Andrade, AC | 1 |
| Timerman, L | 2 |
| Gallottini, M | 1 |
| Itagiba Neves, IL | 1 |
| Ortega, KL | 1 |
| Pearcy, C | 1 |
| Almahmoud, K | 1 |
| Jackson, T | 1 |
| Hartline, C | 1 |
| Cahill, A | 1 |
| Spence, L | 1 |
| Kim, D | 1 |
| Olatubosun, O | 1 |
| Todd, SR | 1 |
| Campion, EM | 1 |
| Burlew, CC | 1 |
| Regner, J | 1 |
| Frazee, R | 1 |
| Michaels, D | 1 |
| Dissanaike, S | 1 |
| Stewart, C | 1 |
| Foley, N | 1 |
| Nelson, P | 1 |
| Agrawal, V | 1 |
| Truitt, MS | 1 |
| Prader, R | 1 |
| De Broca, B | 1 |
| Chevallier, D | 1 |
| Amiel, J | 1 |
| Durand, M | 1 |
| Zhang, C | 1 |
| Wang, G | 2 |
| Liu, X | 1 |
| Li, Y | 1 |
| Sun, J | 1 |
| Sharifi, M | 1 |
| Kamali, A | 1 |
| Ghandi, Y | 1 |
| Cheng, A | 1 |
| Poon, MTC | 1 |
| Demetriades, AK | 1 |
| Baschin, M | 1 |
| Selleng, S | 1 |
| Hummel, A | 1 |
| Diedrich, S | 1 |
| Schroeder, HW | 2 |
| Kohlmann, T | 1 |
| Westphal, A | 1 |
| Greinacher, A | 2 |
| Thiele, T | 2 |
| Gelli, M | 1 |
| Allard, MA | 1 |
| Farges, O | 1 |
| Paugam-Burtz, C | 1 |
| Mabrut, JY | 1 |
| Regimbeau, JM | 1 |
| Vibert, E | 1 |
| Boleslawski, E | 1 |
| Raggio, BS | 1 |
| Barton, BM | 1 |
| Kandil, E | 1 |
| Friedlander, PL | 1 |
| Sobh, AH | 1 |
| Koueiter, DM | 1 |
| Mells, A | 1 |
| Siljander, MP | 1 |
| Karadsheh, MS | 1 |
| Mahla, E | 2 |
| Metzler, H | 2 |
| Bornemann-Cimenti, H | 1 |
| Prueller, F | 2 |
| Raggam, RB | 2 |
| Pregartner, G | 2 |
| Berghold, A | 2 |
| Baumann, A | 1 |
| Goeroeg, C | 1 |
| Gurbel, PA | 2 |
| Lindquist, DE | 1 |
| Stewart, DW | 1 |
| Brewster, A | 1 |
| Waldroup, C | 1 |
| Odle, BL | 1 |
| Burchette, JE | 1 |
| El-Bazouni, H | 1 |
| Tamhankar, AS | 1 |
| Patil, SR | 1 |
| Ahluwalia, P | 1 |
| Gautam, G | 1 |
| Yelnik, CM | 1 |
| Lambert, M | 1 |
| Drumez, E | 1 |
| Le Guern, V | 1 |
| Bacri, JL | 1 |
| Guerra, MM | 1 |
| Laskin, CA | 1 |
| Branch, DW | 1 |
| Sammaritano, LR | 1 |
| Morel, N | 1 |
| Guettrot-Imbert, G | 1 |
| Launay, D | 1 |
| Hachulla, E | 1 |
| Hatron, PY | 1 |
| Salmon, JE | 1 |
| Costedoat-Chalumeau, N | 1 |
| Stamenovic, D | 1 |
| Schneider, T | 1 |
| Messerschmidt, A | 1 |
| Kremke, M | 1 |
| Gissel, MS | 1 |
| Jensen, MJ | 1 |
| Thomassen, SA | 1 |
| Jakobsen, CJ | 1 |
| Horikawa, Y | 1 |
| Mizutamari, H | 1 |
| Mimori, N | 1 |
| Kato, Y | 1 |
| Sawaguchi, M | 1 |
| Fushimi, S | 1 |
| Sato, S | 1 |
| Okubo, S | 1 |
| Zhu, P | 1 |
| Chen, Y | 1 |
| Wang, H | 1 |
| Song, B | 1 |
| Singh, S | 1 |
| Damén, T | 1 |
| Dellborg, M | 1 |
| Jeppsson, A | 1 |
| Nygren, A | 1 |
| Sakamoto, Y | 1 |
| Kawamura, Y | 1 |
| Nagalla, S | 1 |
| Sarode, R | 1 |
| Wessels, F | 1 |
| Kriegmair, MC | 1 |
| Oehme, A | 1 |
| Rassweiler-Seyfried, MC | 1 |
| Erben, P | 1 |
| Oberneder, R | 1 |
| Kriegmair, M | 1 |
| Ritter, M | 1 |
| Michel, MS | 1 |
| Honeck, P | 1 |
| Chen, CF | 1 |
| Tsai, SW | 1 |
| Wu, PK | 1 |
| Chen, CM | 1 |
| Chen, WM | 1 |
| Chatterton, S | 1 |
| Dignan, R | 1 |
| Luu, Q | 1 |
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| Wunderlich, H | 2 |
| Schubert, J | 2 |
| Assia, EI | 1 |
| Raskin, T | 1 |
| Kaiserman, I | 1 |
| Rotenstreich, Y | 1 |
| Segev, F | 1 |
| Alvarez, JM | 1 |
| Harper, RW | 1 |
| Peverill, RE | 1 |
| Alderman, EL | 1 |
| Rich, JB | 1 |
| Nili, M | 1 |
| Vidne, B | 1 |
| Schaff, H | 1 |
| Uretzky, G | 1 |
| Pettersson, G | 1 |
| Thiis, JJ | 1 |
| Hantler, CB | 1 |
| Chaitman, B | 1 |
| Nadel, A | 1 |
| Ivert, T | 1 |
| Intonti, M | 1 |
| Stain-Malmgren, R | 1 |
| Dumitrescu, A | 1 |
| Blombäck, M | 1 |
| Klein, M | 1 |
| Keith, PR | 1 |
| Dauben, HP | 1 |
| Schulte, HD | 1 |
| Beckmann, H | 1 |
| Mayer, G | 1 |
| Elert, O | 1 |
| Gams, E | 1 |
| Aylward, P | 1 |
| Dickinson, JP | 1 |
| Prentice, CR | 1 |
| Kokolakis, S | 1 |
| Zafirakis, P | 1 |
| Livir-Rallatos, G | 1 |
| Ladas, I | 1 |
| Damanakis, A | 1 |
| Del Toro, MF | 1 |
| Stark, WJ | 1 |
| Bell, WR | 1 |
| Klingman, R | 1 |
| Bufo, A | 1 |
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| Hunt, BJ | 3 |
| Bartlett, GR | 1 |
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| Patel, A | 1 |
| Toomey, JR | 1 |
| Bugelski, P | 1 |
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| Church, WR | 1 |
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| Baker, A | 1 |
| Blackburn, MN | 1 |
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| Peled, M | 1 |
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| Bidstrup, BP | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial[NCT05325671] | 120 participants (Anticipated) | Interventional | 2022-04-05 | Not yet recruiting | |||
| Effects of Antiplatelets Discontinuation in Patients Receiving Polypectomy: Randomized Controlled Trial[NCT02865824] | 180 participants (Anticipated) | Interventional | 2016-01-31 | Enrolling by invitation | |||
| Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)[NCT00198068] | 700 participants (Anticipated) | Observational | 2003-09-30 | Recruiting | |||
| Association Between Perioperative Bleeding and Aspirin Use in Spine Surgery: A Randomized, Controlled Trial[NCT02807441] | Phase 3 | 0 participants (Actual) | Interventional | 2016-07-31 | Withdrawn | ||
| Comparison of Combined Topical Tranexamic Acid With Floseal® With Intravenous Tranexamic Acid on Blood Loss in Total Knee Arthroplasty[NCT03328832] | Phase 4 | 70 participants (Actual) | Interventional | 2017-09-12 | Completed | ||
| Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery[NCT03902275] | 20 participants (Actual) | Interventional | 2019-07-01 | Terminated (stopped due to SARS-CoV-2 Pandemic) | |||
| Does Platelet Inhibition Predict Surgery Related Bleeding in Patients Undergoing Emergent Cardiac Surgery During Dual Antiplatelet Therapy - a Pilot Study[NCT01468597] | 167 participants (Actual) | Observational | 2011-01-31 | Completed | |||
| Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery - a Prospective Observational Study[NCT01354847] | 25 participants (Actual) | Observational | 2011-06-30 | Completed | |||
| A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615] | 300 participants (Anticipated) | Interventional | 2014-08-31 | Enrolling by invitation | |||
| Maintenance of an Antiaggregation by Acetylsalicylic Acid, Less or Equal to 250mg While a Extracorporeal Lithotripsy (ECL) Session on a Kidney Stone is Perfomed: Comparative Unicentric Prospective Study[NCT03437057] | 300 participants (Anticipated) | Interventional | 2018-01-08 | Recruiting | |||
| A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention[NCT00097591] | Phase 3 | 13,619 participants (Actual) | Interventional | 2004-11-30 | Completed | ||
| Platelet Aggregometry to Drive the Surgical Timing in Elderlies With Hip Fracture and Receiving Clopidogrel.[NCT04642209] | 9 participants (Anticipated) | Observational | 2020-12-01 | Not yet recruiting | |||
| Recovery of Platelet Function Following Discontinuation of Prasugrel or Clopidogrel Maintenance Dosing in Aspirin-Treated Subjects With Stable Coronary Disease[NCT01014624] | Phase 4 | 56 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| A Double Blind Randomized Control Trial of Post-Operative Low Molecular Weight Heparin Bridging Therapy Versus Placebo Bridging Therapy for Patients Who Are at High Risk for Arterial Thromboembolism (PERIOP 2)[NCT00432796] | Phase 3 | 1,473 participants (Actual) | Interventional | 2006-12-31 | Active, not recruiting | ||
| Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery[NCT03445273] | 1,800 participants (Anticipated) | Observational [Patient Registry] | 2018-11-21 | Not yet recruiting | |||
| Effect of Low Molecular Weight Heparin vs Unfractionated Heparin on Bleeding After Cardiac Surgery[NCT00420667] | 43 participants (Actual) | Interventional | 2004-11-30 | Completed | |||
| Efficacy in Controlling Bleeding Post-coronary Bypass Surgery Using Combination of Local Application of Tranexamic Acid and Intravenous Tranexamic Compared to Intravenous Tranexamic Acid Alone. A Randomized Controlled Trial[NCT01600599] | 40 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
We will record the event of blood transfusion, and calculate the incidence of transfusion (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4
| Intervention | Participants (Count of Participants) |
|---|---|
| Combined Topical TXA and Floseal | 1 |
| Topical TXA Alone | 0 |
The composite of any venous thromoembolism events, ischemic heart attacks, cerebrovascular accidents (NCT03328832)
Timeframe: within 30 days of the operation
| Intervention | Participants (Count of Participants) |
|---|---|
| Combined Topical TXA and Floseal | 0 |
| Topical TXA Alone | 0 |
Total blood loss was calculated according to Nadler et al., which used maximum postoperative reduction of the Hb level adjust for weight and height of the patient. The formula is as follows, Total blood loss = (Total blood volume x [change in Hb level / preoperative Hb level])x1000+volume transfused (NCT03328832)
Timeframe: From the operation to the postoperative day 3 or 4
| Intervention | ml (Mean) |
|---|---|
| Combined Topical TXA and Floseal | 678 |
| Topical TXA Alone | 733 |
Intracranial bleed within 48 hours, Reoperation after closure of sternotomy for the purpose of controlling bleeding, Transfusion of equal to or more than 5 Units of packed red blood cells within a 48-hour period, Chest tube output of equal to or more than 2 L within a 24-h period. (NCT01468597)
Timeframe: until postoperative day 2
| Intervention | participants (Number) |
|---|---|
| One Group | 72 |
(NCT01468597)
Timeframe: until postoperative day 5
| Intervention | milliters (Median) |
|---|---|
| One Group | 1996 |
The endpoint in this measure is a combination of all-cause death, nonfatal MI, or nonfatal stroke. Results are reported for the All ACS population. (NCT00097591)
Timeframe: Randomization up to 15 months
| Intervention | Participants (Number) |
|---|---|
| Prasugrel | 692 |
| Clopidogrel | 822 |
The endpoint in this measure is a combination of CV death, nonfatal MI, nonfatal stroke, or rehospitalization for cardiac ischemic events. Results are reported for the All ACS population. (NCT00097591)
Timeframe: Randomization up to 15 months
| Intervention | Participants (Number) |
|---|---|
| Prasugrel | 797 |
| Clopidogrel | 938 |
The endpoint in this measure is a combination of CV death, nonfatal MI, or nonfatal stroke. Results are reported for the All ACS population for the 30 and 90 day periods. (NCT00097591)
Timeframe: Randomization to 30 days; randomization to 90 days
| Intervention | Participants (Number) | |
|---|---|---|
| All ACS (Through 30 days) | All ACS (Through 90 days) | |
| Clopidogrel | 502 | 573 |
| Prasugrel | 389 | 462 |
The endpoint in this measure is a combination of CV death, nonfatal MI, or nonfatal stroke. The data is presented by the study population, which is represented as follows: 1) subjects who presented with unstable angina and non-ST-segment elevation myocardial infarction (UA/NSTEMI), 2) subjects who presented with ST segment elevation myocardial infarction (STEMI), and 3) all subjects with acute coronary syndromes (ACS) (i.e. all subjects with UA/NSTEMI or STEMI). (NCT00097591)
Timeframe: Randomization up to 15 months
| Intervention | Participants (Number) | ||
|---|---|---|---|
| UA/NSTEMI (n=5044, n=5030) | STEMI (n=1769, n=1765) | All ACS (n=6813, n=6795) | |
| Clopidogrel | 565 | 216 | 781 |
| Prasugrel | 469 | 174 | 643 |
The endpoint in this measure is a combination of CV death, nonfatal MI, or UTVR. Results are reported for the All ACS subject population for the 30 and 90 day periods. (NCT00097591)
Timeframe: Randomization to 30 days; randomization to 90 days
| Intervention | Participants (Number) | |
|---|---|---|
| All ACS (Through 30 days) | All ACS (Through 90 days) | |
| Clopidogrel | 504 | 588 |
| Prasugrel | 399 | 472 |
TIMI classification for major and minor bleeding in the subset of subjects who did not undergo a coronary artery bypass operation (CABG) were defined as follows: Major bleeding: any intracranial hemorrhage (ICH) OR any clinically overt bleeding (including bleeding evident on imaging studies) associated with a fall in hemoglobin (Hgb) of ≥5 grams/deciliter (gm/dL)from baseline. Minor Bleeding: any clinically overt bleeding associated with a fall in Hgb of ≥3 gm/dL but <5 gm/dL from baseline. Major bleeding events were further examined as events that were deemed life threatening and/or fatal. (NCT00097591)
Timeframe: First dose of study drug up to 15 months (while at risk)
| Intervention | Participants (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| TIMI Major or Minor Bleeding | TIMI Major Bleeding | TIMI Major Bleeding - Life-threatening (LT) | LT - Fatal | LT - Symptomatic intracranial hemorrage (ICH) | LT - Requiring inotropes | LT - Requiring surgical intervention | LT - Requiring transfusion (>=4 units) | TIMI Minor Bleeding | |
| Clopidogrel | 231 | 111 | 56 | 5 | 17 | 8 | 19 | 30 | 125 |
| Prasugrel | 303 | 146 | 85 | 21 | 19 | 21 | 19 | 45 | 164 |
Inhibition of platelet aggregation was assessed by Accumetrics VerifyNow® P2Y12 reaction units (PRU). On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hour (+/- 6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/(Baseline PRU) less than or equal to 20%. (NCT01014624)
Timeframe: Washout Day 1
| Intervention | percentage (Mean) |
|---|---|
| Prasugrel | 72.3 |
| Clopidogrel | 35.4 |
Time to return to baseline PRU (<= 60 units of baseline) dependent upon baseline PRU and platelet % inhibition on Washout Period Day 1 but independent of treatment. The following regression model was derived for predicting number of days to return to baseline PRU where PI(1) represents platelet percentage inhibition on Washout Day 1. Number days to return to baseline PRU derived from: Number days to return to baseline PRU=-3.350+0.079*PI(1)+0.014*baseline PRU. The predicted number of days to return to baseline based on device-derived platelet percentage inhibition is reported for each treatment group. (NCT01014624)
Timeframe: up to 12 days after the last dose
| Intervention | days (Number) |
|---|---|
| Prasugrel | 6.2 |
| Clopidogrel | 3.7 |
On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hours (+/-6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participants met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/Baseline PRU less than or equal to 20%. (NCT01014624)
Timeframe: up to 12 days after last dose
| Intervention | days (Number) | ||
|---|---|---|---|
| Washout day 50% returned to baseline PRU | Washout day 75% returned to baseline PRU | Washout day 90% returned to baseline PRU | |
| Clopidogrel | 3 | 5 | 6 |
| Prasugrel | 6 | 7 | 9 |
On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hours (+/-6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/Baseline PRU less than or equal to 20%. (NCT01014624)
Timeframe: up to 12 days after last dose
| Intervention | days (Number) | ||
|---|---|---|---|
| Washout day 50% returned to baseline PRU | Washout day 75% returned to baseline PRU | Washout day 90% returned to baseline PRU | |
| Clopidogrel | 3 | 5 | 7 |
| Prasugrel | 6 | 7 | 9 |
On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hours (+/-6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/Baseline PRU less than or equal to 20%. (NCT01014624)
Timeframe: up to 12 days after last dose
| Intervention | days (Number) | ||
|---|---|---|---|
| Washout day 50% returned to baseline PRU | Washout day 75% returned to baseline PRU | Washout day 90% returned to baseline PRU | |
| Clopidogrel | 5 | 5 | 6 |
| Prasugrel | 6 | 7 | 9 |
On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hour (+/- 6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/(Baseline PRU) less than or equal to (<=) 20%. (NCT01014624)
Timeframe: up to 12 days after the last dose
| Intervention | days (Number) | ||
|---|---|---|---|
| Washout day 50% returned to baseline PRU | Washout day 75% returned to baseline PRU | Washout day 90% returned to baseline PRU | |
| Clopidogrel | 5 | 6 | 7 |
| Prasugrel | 6 | 7 | 9 |
On the first day of the Washout Period (Visit 3), the blood draw for platelet function testing was obtained 24 hours (+/- 6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/(Baseline PRU) less than or equal to 20%. The results are expressed as cumulative percentage of participants. (NCT01014624)
Timeframe: up to 12 days after last dose
| Intervention | cumulative percentage of participants (Number) | |||||
|---|---|---|---|---|---|---|
| return to baseline PRU by washout day 1 | return to baseline PRU by washout day 3 | return to baseline PRU by washout day 5 | return to baseline PRU by washout day 6 | return to baseline PRU by washout day 7 | return to baseline PRU by washout day 9 | |
| Clopidogrel | 30.8 | 53.9 | 84.6 | 96.2 | 96.2 | 100.0 |
| Prasugrel | 0 | 3.6 | 37.0 | 62.9 | 77.8 | 100.0 |
On the first day of the Washout Period (visit 3), the blood draw for platelet function testing was obtained 24 hours (+/- 6 hours) after the last dose of study medication. Following Visit 3, platelet function testing was performed during each visit of the Washout Period until the participant met the following exit criteria: (Baseline PRU-PRU) less than or equal to 60 units and (Baseline PRU-PRU)/(Baseline PRU) less than or equal to 20%. (NCT01014624)
Timeframe: up to 12 days after last dose
| Intervention | cumulative percentage of participants (Number) | |||||
|---|---|---|---|---|---|---|
| returned to baseline PRU by washout day 1 | returned to baseline PRU by washout day 3 | returned to baseline PRU by washout day 5 | returned to baseline PRU by washout day 6 | returned to baseline PRU by washout day 7 | returned to baseline PRU by washout day 9 | |
| Clopidogrel | 30.8 | 53.9 | 80.8 | 88.5 | 96.2 | 100.0 |
| Prasugrel | 0.0 | 0.0 | 37.0 | 55.6 | 77.8 | 100.0 |
34 reviews available for aspirin and Blood Loss, Surgical
| Article | Year |
|---|---|
Controversial Topics in Total Knee Arthroplasty: A Five-Year Update (Part 2).
Topics: Anticoagulants; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgi | 2020 |
A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, Combination; Humans; Platelet Aggregation | 2018 |
Safety of continuing aspirin therapy during spinal surgery: A systematic review and meta-analysis.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Humans; Platelet Aggregation Inhibitors; Postopera | 2017 |
Aspirin therapy discontinuation and intraoperative blood loss in spinal surgery: a systematic review.
Topics: Aspirin; Blood Loss, Surgical; Humans; Operative Time; Platelet Aggregation Inhibitors; Spine; Treat | 2018 |
Role of Platelet Transfusion in the Reversal of Anti-Platelet Therapy.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Cyclooxygenase Inhibitors; Hemorrhage; Hemostasis; H | 2019 |
Aspirin and coronary artery surgery: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiac S | 2015 |
Aspirin and spinal haematoma after neuraxial anaesthesia: Myth or reality?
Topics: Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Lo | 2015 |
Coronary artery stents: II. Perioperative considerations and management.
Topics: Anesthesia, Conduction; Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; | 2008 |
Clopidogrel: mechanisms of action and review of the evidence relating to use during skin surgery procedures.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Dermatologic Surgical Procedures; Drug Therapy, Combinat | 2010 |
Periprocedural antithrombotic management: a review of the literature and practical approach for the hospitalist physician.
Topics: Aspirin; Blood Loss, Surgical; Drug-Eluting Stents; Fibrinolytic Agents; Heparin; Hospitalists; Huma | 2009 |
Comparing consensus guidelines on thromboprophylaxis in orthopedic surgery.
Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Cast | 2010 |
[Discontinuation of treatment with platelet aggregation inhibitors in surgical patients with cardiac stents].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Dru | 2010 |
Prevention of the renarrowing of coronary arteries using drug-eluting stents in the perioperative period: an update.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Coronary Vessels; Drug-Eluting Sten | 2010 |
Antiplatelet therapy in ENT surgery: a review.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Decision Making; Drug-Eluting Stents; Humans; Otorhinola | 2012 |
[Antiplatelet therapy after coronary stenting and its importance in total joint arthroplasty].
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replac | 2012 |
[Acetylsalicylic acid in patients with planned (elective) interventions on the coronary arteries. Risks and benefits].
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Coronary Artery Disease; H | 2012 |
Management of patients taking anticoagulant, aspirin, non-steroidal anti-inflammatory and other anti-platelet drugs undergoing dermatological surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Loss, Surgical; Dermatologic | 2002 |
Antiplatelet drugs : is there a surgical risk?
Topics: Aspirin; Blood Coagulation Disorders; Blood Loss, Surgical; Cyclooxygenase Inhibitors; Decision Tree | 2002 |
[Withdrawing the use of acetylsalicyclic acid prior to an operation usually not necessary].
Topics: Aspirin; Blood Loss, Surgical; Cyclooxygenase Inhibitors; Humans; Incidence; Platelet Aggregation In | 2003 |
Controversies in perioperative management of blood thinners in dermatologic surgery: continue or discontinue?
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Care; Intraoperative Complicat | 2004 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Cardiovascula | 2005 |
Management of antiplatelet therapy for minimization of bleeding risk before cardiac surgery.
Topics: Adenosine Diphosphate; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Coronary Thrombosis; H | 2006 |
[Antiplatelet drugs and intraoperative hemorrhage].
Topics: Algorithms; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug Therapy, Combinati | 2006 |
The effect of pre-operative aspirin on bleeding, transfusion, myocardial infarction, and mortality in coronary artery bypass surgery: a systematic review of randomized and observational studies.
Topics: Aged; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Coronary Thrombosis; Female; Humans; Ma | 2008 |
Limiting excessive postoperative blood transfusion after cardiac procedures. A review.
Topics: Aspirin; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; H | 1995 |
[Drug modification of blood loss].
Topics: Adult; Aprotinin; Aspirin; Blood Loss, Surgical; Deamino Arginine Vasopressin; Extracorporeal Circul | 1993 |
Management of patients taking anticoagulants and platelet inhibitors prior to dermatologic surgery.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Clinical Protocols; Humans; Patient Care Planning; Po | 1993 |
Hemorrhage and the use of blood products after adult cardiac operations: myths and realities.
Topics: Adult; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Drainage; Huma | 1996 |
Pharmacological prophylaxis of bleeding in surgical patients treated with aspirin.
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Deamino Arginine Vasopressin; Hemostatics; Humans; Platele | 1997 |
[Does treatment with thrombocyte aggregation inhibitors modify kidney transplantation surgery?].
Topics: Aspirin; Blood Loss, Surgical; Dose-Response Relationship, Drug; Hemostasis, Surgical; Humans; Kidne | 1998 |
Aspirin: benefit and risk in thromboprophylaxis.
Topics: Aspirin; Blood Loss, Surgical; Case-Control Studies; Gastrointestinal Hemorrhage; Humans; Platelet A | 1998 |
Cardiopulmonary bypass.
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Cardiac Surgical Procedures; Cardioplegic Solutions; Cardi | 1991 |
[Aspirin, a risk factor for bleeding at dental procedures].
Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Complications; Oral H | 1995 |
The impact of medical therapy on hemorrhagic complications following coronary artery bypass grafting.
Topics: Aspirin; Blood Loss, Surgical; Calcium Channel Blockers; Cardiopulmonary Bypass; Coronary Artery Byp | 1990 |
49 trials available for aspirin and Blood Loss, Surgical
| Article | Year |
|---|---|
Effect of topical tranexamic acid in total hip arthroplasty patients who receive continuous aspirin for prevention of cardiovascular or cerebrovascular events: A prospective randomized study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement | 2019 |
Cold Snare Polypectomy in Patients Taking Dual Antiplatelet Therapy: A Randomized Trial of Discontinuation of Thienopyridines.
Topics: Aged; Aspirin; Atherosclerosis; Blood Loss, Surgical; Colonic Polyps; Colonoscopy; Colorectal Neopla | 2019 |
Effect of Sustained Use of Aspirin until the Time of Surgery on Outcomes following Coronary Artery Bypass Grafting: A Randomized Clinical Trial.
Topics: Aged; Aspirin; Blood Loss, Surgical; Cardiovascular Agents; Coronary Artery Bypass; Coronary Artery | 2018 |
Preoperative antiplatelet drugs on the hemorrhage and allogenic blood transfusion condition after coronary artery bypass graft surgery.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; | 2018 |
Intraoperative infusion of noradrenaline improves platelet aggregation in patients undergoing coronary artery bypass grafting: a randomized controlled trial.
Topics: Aged; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Drug Administration Schedule; Female; H | 2019 |
Platelet Activity Measured by VerifyNow® Aspirin Sensitivity Test Identifies Coronary Artery Bypass Surgery Patients at Increased Risk for Postoperative Bleeding and Transfusion.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Transfusion; Coronary Artery Bypass; Fem | 2020 |
Assessment of the risk of haemorrhage and its control following minor oral surgical procedures in patients on anti-platelet therapy: a prospective study.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Female; Hemostasis, Surgical; Humans; Male; | 2014 |
[Effects of preoperative uses of aspirin and clopidogrel on patients undergoing coronary artery bypass graft surgery].
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass, Off-Pump; Female; Humans; | 2013 |
Preoperative platelet aggregation predicts perioperative blood loss and rethoracotomy for bleeding in patients receiving dual antiplatelet treatment prior to coronary surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Drug Combinations; Female; Human | 2015 |
Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; D | 2015 |
Closed Suction Drainage Has No Benefits in Anterior Hip Arthroplasty: A Prospective, Randomized Trial.
Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Aspirin; Bl | 2016 |
To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Double-Blind Method | 2010 |
To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Double-Blind Method | 2010 |
To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Double-Blind Method | 2010 |
To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Double-Blind Method | 2010 |
Bleeding evaluation during single tooth extraction in patients with coronary artery disease and acetylsalicylic acid therapy suspension: a prospective, double-blinded, and randomized study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Chi-Square Distribution; Coronary Dis | 2011 |
Effect of hydroxyethyl starch 130/0.4 on blood loss and coagulation in patients with recent exposure to dual antiplatelet therapy undergoing off-pump coronary artery bypass graft surgery.
Topics: Aged; Aspirin; Blood Coagulation; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass, Off-Pum | 2011 |
Optimal timing of discontinuation of clopidogrel and risk of blood transfusion after coronary surgery. Propensity score analysis.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiac Surgical Procedures; Clopidogrel; Fe | 2011 |
A randomised controlled pilot trial to evaluate and optimize the use of anti-platelet agents in the perioperative management in patients undergoing general and abdominal surgery--the APAP trial (ISRCTN45810007).
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cholecystectomy; Colorectal Surgery; | 2012 |
Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Cause | 2012 |
Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Clopidogrel; Confounding Factors, Epide | 2012 |
Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Clopidogrel; Confounding Factors, Epide | 2012 |
Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Clopidogrel; Confounding Factors, Epide | 2012 |
Recovery of platelet function after discontinuation of prasugrel or clopidogrel maintenance dosing in aspirin-treated patients with stable coronary disease: the recovery trial.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Blood Platelets; Clopidogrel; Confounding Factors, Epide | 2012 |
Tranexamic Acid in on-pump coronary artery bypass grafting without clopidogrel and aspirin cessation: randomized trial and 1-year follow-up.
Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronar | 2013 |
Effect of diaspirin crosslinked hemoglobin (DCLHb HemAssist) during high blood loss surgery on selected indices of organ function.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Substitutes; Digestive System; Digestive System Surgical | 2002 |
Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin.
Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Atrial Fibrillation; Blood Loss, Surgical; Coh | 2004 |
Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism.
Topics: Alleles; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Double-Blind Method; Female; Humans; | 2005 |
Aprotinin shows both hemostatic and antithrombotic effects during off-pump coronary artery bypass grafting.
Topics: Aprotinin; Aspirin; Biomarkers; Blood Coagulation Tests; Blood Loss, Surgical; Coronary Artery Bypas | 2006 |
[Tooth extraction under medication with acetylsalicylic acid].
Topics: Administration, Oral; Aged; Analgesics; Aspirin; Blood Loss, Surgical; Dose-Response Relationship, D | 2006 |
Assessment of bleeding after concomitant administration of antiplatelet and anticoagulant agents in lower limb arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthroplast | 2006 |
Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgery.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Drug Administ | 2007 |
Aprotinin significantly decreases bleeding and transfusion requirements in patients receiving aspirin and undergoing cardiac operations.
Topics: Aged; Aprotinin; Aspirin; Blood Loss, Surgical; Blood Transfusion; Blood Volume; Cardiac Surgical Pr | 1994 |
Topical aprotinin in cardiac operations.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Algorithms; Aortic Valve; Aprotinin; Aspiri | 1994 |
Hemostatic function of aspirin-treated platelets vulnerable to cardiopulmonary bypass. Altered shear-induced pathway.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Coagulation Tests; Blood Loss, Surgical; Blood Platelets | 1995 |
1988: Preoperative aspirin ingestion increases operative blood loss after coronary artery bypass grafting. Updated in 1995.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Blo | 1995 |
Bleeding time and bleeding: an analysis of the relationship of the bleeding time test with parameters of surgical bleeding.
Topics: Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Chest Pain; Cohort Studies; Coronar | 1994 |
Pre-operative aspirin decreases platelet aggregation and increases post-operative blood loss--a prospective, randomised, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina.
Topics: Aspirin; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; C | 1994 |
The prevalence of deep venous thrombosis after total hip arthroplasty with hypotensive epidural anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Aspirin; Blood Loss, Surgical; Female; Gravity | 1994 |
Use of desmopressin acetate to reduce blood transfusion requirements during cardiac surgery in patients with acetylsalicylic-acid-induced platelet dysfunction.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Transfusion; Blood Volume; Coronary Artery Byp | 1994 |
Influence of desmopressin acetate on homologous blood requirements in cardiac surgical patients pretreated with aspirin.
Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Blood Transfusion; Deamin | 1993 |
Thromboembolism after THR: prophylaxis and treatment.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, General; Aspirin; Bandages; Blood Loss, Surgical; Fem | 1995 |
A randomised trial of fibrin sealant in peripheral vascular surgery.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm; Aspirin; Blood Loss, Surgical; Blood Vessel Prosthesis; Fe | 1996 |
[A prospective study on the timing of discontinuation of aspirin before coronary artery bypass grafting].
Topics: Aged; Aspirin; Blood Loss, Surgical; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Diseas | 1997 |
Effect of aspirin intake on bleeding during cataract surgery.
Topics: Aspirin; Blood Loss, Surgical; Cataract Extraction; Eye Hemorrhage; Fibrinolytic Agents; Follow-Up S | 1998 |
Analyses of coronary graft patency after aprotinin use: results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aprotinin; Aspirin; Blood Loss, Surgical; Card | 1998 |
Effects of aprotinin during cardiopulmonary bypass in patients treated with acetylsalicylic acid.
Topics: Adenosine Triphosphate; Adult; Aged; Angina, Unstable; Aprotinin; Aspirin; Blood Loss, Surgical; Blo | 1998 |
Aprotinin counterbalances an increased risk of peri-operative hemorrhage in CABG patients pre-treated with Aspirin.
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Creatine Kinase; Double-Blind Meth | 1998 |
Does low-dose aspirin therapy complicate oral surgical procedures?
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; | 2000 |
Amelioration of the bleeding tendency of preoperative aspirin after aortocoronary bypass grafting.
Topics: Adult; Antifibrinolytic Agents; Antithrombin III; Aprotinin; Aspirin; Blood Loss, Surgical; Coronary | 2000 |
Comparison of two doses of aprotinin in patients receiving aspirin before coronary bypass surgery.
Topics: Adult; Aged; Aprotinin; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Co | 2000 |
The effect of low-dose acetylsalicylic acid on bleeding after transurethral prostatectomy--a prospective, randomized, double-blind, placebo-controlled study.
Topics: Aged; Aspirin; Blood Loss, Surgical; Double-Blind Method; Humans; Male; Postoperative Hemorrhage; Po | 2000 |
Hemoglobin and methemoglobin concentrations after large-dose infusions of diaspirin cross-linked hemoglobin.
Topics: Aspirin; Blood Loss, Surgical; Blood Substitutes; Dose-Response Relationship, Drug; Erythrocyte Tran | 2001 |
Aprotinin therapy for reoperative myocardial revascularization: a placebo-controlled study.
Topics: Aged; Aprotinin; Aspartate Aminotransferases; Aspirin; Blood Loss, Surgical; Blood Transfusion; Ches | 1992 |
Treatment with desmopressin acetate in routine coronary artery bypass surgery to improve postoperative hemostasis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Blood Transfusion; Coronary | 1990 |
162 other studies available for aspirin and Blood Loss, Surgical
| Article | Year |
|---|---|
Perioperative Aspirin Use Is Associated with Bleeding Complications during Robotic Partial Nephrectomy.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Female; Humans; Kidney Neoplasms; Male; Midd | 2022 |
Perioperative continuation of aspirin, oral anticoagulants or bridging with therapeutic low-molecular-weight heparin does not increase intraoperative blood loss and blood transfusion rate in cystectomy patients: an observational cohort study.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cohort Studies; Cystectomy; Hepari | 2022 |
Preoperative Use of Aspirin in Total Knee Arthroplasty: Safe or Not?
Topics: Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Blood Transfusion; Hemoglobins; Huma | 2022 |
Effect of perioperative aspirin continuation on bleeding after pneumonectomy.
Topics: Aspirin; Blood Loss, Surgical; Humans; Platelet Aggregation Inhibitors; Pneumonectomy; Retrospective | 2023 |
Full Reversal of Anticoagulants Before Cephalomedullary Fixation of Geriatric Hip Fractures May Not Be Necessary.
Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Cohort Studies; Hip Fractures; Humans; Platelet | 2023 |
Impact of perioperative aspirin continuation on bleeding complications in laparoscopic colorectal cancer surgery: a propensity score-matched analysis.
Topics: Aged; Aged, 80 and over; Anastomosis, Surgical; Aspirin; Blood Loss, Surgical; Blood Transfusion; Co | 2021 |
Cranberry supplementation as a cause of major intraoperative bleeding during vascular surgery due to aspirin-like platelet inhibition.
Topics: Aged; Aortic Aneurysm, Thoracic; Aspirin; Blood Loss, Surgical; Dietary Supplements; Female; Hemorrh | 2020 |
Is continuation of anti-platelet treatment safe for elective total hip arthroplasty patients?
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Arthroplasty, Replacement, Hip; Aspirin; Blood Los | 2020 |
Retrospective high volume comparative study suggests that patients on aspirin could have immediate surgery for hip fractures without significant blood loss.
Topics: Aged; Aspirin; Blood Loss, Surgical; Hip Fractures; Humans; Platelet Aggregation Inhibitors; Retrosp | 2021 |
Safety and feasibility of liver resection with continued antiplatelet therapy using aspirin.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Feasibility Studies | 2017 |
Quantification of bleeding during dental extraction in patients on dual antiplatelet therapy.
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Clopidogrel; Dental Ca | 2017 |
Risky business? Investigating outcomes of patients undergoing urgent laparoscopic appendectomy on antithrombotic therapy.
Topics: Adult; Appendectomy; Appendicitis; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Fe | 2017 |
Outcome of Transurethral Resection of Bladder Tumor: Does Antiplatelet Therapy Really Matter? Analysis of a Retrospective Series.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carcinoma, Transitional Cell; Clopidogrel; C | 2017 |
Preoperative platelet transfusions to reverse antiplatelet therapy for urgent non-cardiac surgery: an observational cohort study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Administration Sche | 2018 |
Use of aspirin and bleeding-related complications after hepatic resection.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Drug Administration Schedule; Elective Surgical Procedur | 2018 |
Association of Continued Preoperative Aspirin Use and Bleeding Complications in Patients Undergoing Thyroid Surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Hematoma; Humans; Middle | 2018 |
The Role of Aspirin and Unfractionated Heparin Combination Therapy Immediately After Total Hip and Knee Arthroplasty.
Topics: Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Bloo | 2018 |
Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery-The BIANCA Observational Study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Platelets; Cell Adhesion Molecules; Cl | 2018 |
Comparison of Postoperative Bleeding in Total Hip and Knee Arthroplasty Patients Receiving Rivaroxaban, Enoxaparin, or Aspirin for Thromboprophylaxis.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Asp | 2018 |
Does Continuation of Low-Dose Aspirin During Robot-Assisted Radical Prostatectomy Compromise Surgical Outcomes?
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Drainage; Hemoglobins; Humans; Male; Middle | 2018 |
Bleeding complications and antithrombotic treatment in 264 pregnancies in antiphospholipid syndrome.
Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Blood Loss, Surgical; Blood Transfusion; | 2018 |
Aspirin for patients undergoing major lung resections: hazardous or harmless?†.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; Female; Humans; Lun | 2019 |
The association between a three-day ticagrelor discontinuation and perioperative bleeding complications.
Topics: Aged; Aspirin; Blood Loss, Surgical; Cardiac Surgical Procedures; Coronary Artery Bypass; Female; He | 2019 |
Effect of Continued Administration of Low-dose Aspirin for Intraoperative Bleeding Control in Gastric Endoscopic Submucosal Dissection.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Case-Control Studies; Endoscopic Muco | 2019 |
Safety of elective laparoscopic cholecystectomy in patients with antiplatelet therapy: Lessons from more than 800 operations in a single tertiary referral institution.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cholecystectomy, Laparoscopic; Elective Surg | 2020 |
Radical cystectomy under continuous antiplatelet therapy with acetylsalicylic acid.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; Case-Control Studie | 2019 |
Does continued aspirin mono-therapy lead to a higher bleeding risk after total knee arthroplasty?
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Humans; Mid | 2019 |
Optimal use of antiplatelet agents, especially aspirin, in the perioperative management of colorectal cancer patients undergoing laparoscopic colorectal resection.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Colorectal Neoplasms; Female; Follow- | 2019 |
Is laparoscopic colorectal surgery with continuation of antiplatelet therapy safe without increasing bleeding complications?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Digestive System Surgical Procedures; | 2019 |
The Safety of Continuing Antiplatelet Medication Among Elderly Patients Undergoing Urgent Hip Fracture Surgery.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Dipyridamole; Drug Therap | 2019 |
Intractable intraoperative bleeding requiring platelet transfusion during emergent cholecystectomy in a patient with dual antiplatelet therapy after drug-eluting coronary stent implantation (with video).
Topics: Aged; Aspirin; Blood Loss, Surgical; Cholecystectomy; Coronary Artery Disease; Drug-Eluting Stents; | 2013 |
Perioperative management of a neurosurgical patient with a meningioma and recent coronary artery stent.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Contraindications; Coronary Artery Disease; Drug T | 2013 |
Safety of perioperative aspirin therapy in pancreatic operations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Female; Humans; Length of | 2014 |
Ticlopidine and clopidogrel, sometimes combined with aspirin, only minimally increase the surgical risk in renal transplantation: a case-control study.
Topics: Aspirin; Blood Loss, Surgical; Case-Control Studies; Clopidogrel; Dose-Response Relationship, Drug; | 2014 |
Comparison of blood loss according to use of aspirin in lumbar fusion patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Tests; Blood Loss, Surgica | 2014 |
Letter to the Editor concerning "Comparison of blood loss according to use of aspirin in lumbar fusion patients" (by Park HJ, Kwon KY, Woo JH (2014) Eur Spine J. doi:10.1007/s00586-014-3294-y).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Lumbar Verte | 2014 |
Answer to the Letter to the Editor of Liang Ding et al. concerning "Comparison of blood loss according to use of aspirin in lumbar fusion patients" (by Park HJ, Kwon KY, Woo JH (2014) Eur Spine J. doi:10.1007/s00586-014-3294-y).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Lumbar Verte | 2014 |
Continuing aspirin therapy during percutaneous nephrolithotomy: unsafe or under-utilized?
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiovascular Diseases; Cohort Studies; Fem | 2014 |
Effects of Perioperative Acetyl Salicylic Acid on Clinical Outcomes in Patients Undergoing Craniotomy for Brain Tumor.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Brain Neoplasms; Child; C | 2015 |
Non-instrumented extradural lumbar spine surgery under low-dose acetylsalicylic acid: a comparative risk analysis study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Case-Control Studies; Cor | 2016 |
Effects of platelet infusion, anticoagulant and other risk factors on the rehaemorrhagia after surgery of hypertensive cerebral hemorrhage.
Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Female; Hematoma; Humans; Intracranial Hemorrha | 2015 |
Percutaneous dilatational tracheostomy in a patient on antiplatelet therapy with ticagrelor and Aspirin: a case report.
Topics: Adenosine; Aspirin; Blood Loss, Surgical; Dilatation; Female; Humans; Middle Aged; Platelet Aggregat | 2015 |
Use of a haemostatic matrix (Floseal®) does not reduce blood loss in minimally invasive total knee arthroplasty performed under continued aspirin.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Female; Gel | 2016 |
Dual Antiplatelet Therapy Prior to Expedited Carotid Surgery Reduces Recurrent Events Prior to Surgery without Significantly Increasing Peri-operative Bleeding Complications.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Stenosis; Clopidogrel; Drug A | 2015 |
Aspirin and clopidogrel during robotic partial nephrectomy, is it safe?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Feasibility Studies; Fem | 2015 |
Predicting Bleeding Risk by Platelet Function Testing in Patients Undergoing Heart Surgery.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Aspirin; Blood Loss, Surgical; Cardiopulmonary Byp | 2015 |
Outcomes of Laparoscopic Partial Nephrectomy in Patients Continuing Aspirin Therapy.
Topics: Aspirin; Blood Loss, Surgical; Feasibility Studies; Humans; Laparoscopy; Length of Stay; Nephrectomy | 2016 |
Cochlear Implantation in the Setting of Perioperative Anticoagulation and Antiplatelet Therapy.
Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cochlear Implantation; Female; Hem | 2016 |
Sonorheometry assessment of platelet function in cardiopulmonary bypass patients: Correlation of blood clot stiffness with platelet integrin αIIbβ3 activity, aspirin usage, and transfusion risk.
Topics: Aged; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Loss, Surgical; Blood Platelets; Bl | 2016 |
Dental extraction without stopping single or dual antiplatelet therapy: results of a retrospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Female; Humans; Male; Middle Aged; Pl | 2016 |
Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis.
Topics: Aged; Antifibrinolytic Agents; Arthroplasty; Aspirin; Blood Loss, Surgical; Cohort Studies; Female; | 2016 |
Is preoperative withdrawal of aspirin necessary in patients undergoing elective inguinal hernia repair?
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Drug Administration Schedule; Elective Surgical Procedur | 2016 |
Effects of Sarpogrelate Combined with Aspirin in Patients Undergoing Carotid Endarterectomy in China: A Single-Center Retrospective Study.
Topics: Aged; Aspirin; Blood Loss, Surgical; Carotid Stenosis; China; Clopidogrel; Drug Therapy, Combination | 2016 |
Associations between antithrombotic therapy and the risk of perioperative complications among patients undergoing laparoscopic gastrectomy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Female; Fibrinolytic Agents; Gastrect | 2017 |
Does Platelet Reactivity Predict Bleeding in Patients Needing Urgent Coronary Artery Bypass Grafting During Dual Antiplatelet Therapy?
Topics: Aged; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Drug Therapy, Combination; Emergencies; | 2016 |
Perioperative Outcomes Following Partial Nephrectomy Performed on Patients Remaining on Antiplatelet Therapy.
Topics: Age Factors; Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Carcinoma, Renal Cell; Clopidog | 2017 |
Comparison of preoperative continuation and discontinuation of aspirin in patients undergoing total hip or knee arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Femal | 2016 |
Perioperative antiplatelet therapy and cardiovascular outcomes in patients undergoing joint and spine surgery.
Topics: Aged; Aspirin; Blood Loss, Surgical; Coronary Artery Disease; Erythrocyte Transfusion; Female; Human | 2016 |
[Bleeding or stent thrombosis in combination with drug-eluting stents].
Topics: Aneurysm, False; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Drug-Eluting St | 2009 |
An assessment of cardiopulmonary bypass-induced changes in platelet function using whole blood and classical light transmission aggregometry: the results of a pilot study.
Topics: Aged; Anesthesia; Aspirin; Blood Loss, Surgical; Blood Platelets; Cardiopulmonary Bypass; Clopidogre | 2009 |
Premature preoperative discontinuation of antiplatelet drug therapy in cardiovascular risk patients: a preliminary study on the role of P2Y12 receptor monitoring.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; Cell Adhe | 2010 |
[Hidden blood loss after lumbar spinal stenosis operation].
Topics: Aged; Aspirin; Blood Loss, Surgical; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Postoperat | 2009 |
Should dual antiplatelet therapy after drug-eluting stents be continued for more than 1 year?: Dual antiplatelet therapy after drug-eluting stents should not be continued for more than 1 year and preferably indefinitely.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Restenosis; Cor | 2008 |
How can we reduce disagreement among guidelines for venous thromboembolism prevention?
Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Cast | 2010 |
Safety of carotid endarterectomy while on clopidogrel (Plavix). Clinical article.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; Edema; E | 2010 |
[Comment about patients with dual antiplatelet therapy].
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Contraindications; Drug Therapy, Combina | 2010 |
Clinical pharmacology: antiplatelet therapy during surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Humans; Perioperative Care; Platelet Aggregation Inhibit | 2010 |
Evaluation of the need to discontinue antiplatelet and anticoagulant medications before cataract surgery.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Eye Hemorrhage; Female; Huma | 2010 |
Initial experience with an institutional bridging protocol for patients with recent coronary stent implantation requiring discontinuation of dual antiplatelet therapy resulting from urgent surgery.
Topics: Antithrombins; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Thrombosis; Drug-Eluting Stents; | 2011 |
On the use of prothrombin complex concentrate in patients with coagulopathy requiring tooth extraction.
Topics: Adult; Aspirin; Blood Coagulation Factors; Blood Loss, Surgical; Cellulose, Oxidized; Contraindicati | 2010 |
Stopping aspirin before coronary artery surgery: between the devil and the deep blue sea.
Topics: Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Humans; Preoperative Care; Thrombosis; Withho | 2011 |
Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in coronary artery bypass surgery.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Female; Hospital Mor | 2011 |
The effect of clopidogrel and aspirin on blood loss in hip fracture surgery.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Drug Therapy | 2011 |
Peri-operative management of antiplatelet therapy in patients with coronary artery disease: joint position paper by members of the working group on Perioperative Haemostasis of the Society on Thrombosis and Haemostasis Research (GTH), the working group on
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Surgical Procedures; Clopidogrel; Contraindications; C | 2011 |
Does low-dose aspirin increase blood loss after spinal fusion surgery?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Male; | 2011 |
Does low-dose aspirin increase blood loss after spinal fusion surgery?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Male; | 2011 |
Does low-dose aspirin increase blood loss after spinal fusion surgery?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Male; | 2011 |
Does low-dose aspirin increase blood loss after spinal fusion surgery?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; Male; | 2011 |
How do we manage patients treated with antithrombotic therapy in the perioperative interval.
Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Aspirin; Blood Loss, Surgical; Blood Transfu | 2011 |
Intraoperative bleeding during open flap debridement and regenerative periodontal surgery.
Topics: Adult; Age Factors; Aged; Alveolar Bone Loss; Anesthetics, Local; Aspirin; Blood Loss, Surgical; Bon | 2012 |
Risk assessment of simple phacoemulsification in patients on combined anticoagulant and antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, C | 2011 |
Emergency surgery following trancutaneous aortic valve insertion.
Topics: Aged, 80 and over; Aortic Valve; Aspirin; Blood Loss, Surgical; Clopidogrel; Emergency Medical Servi | 2011 |
Perioperative management of patients receiving anticoagulant or antiplatelet therapy: a clinician-oriented and practical approach.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Evidence-Based Medicine; Humans; Periope | 2011 |
Bleeding and first-year mortality following hip fracture surgery and preoperative use of low-dose acetylsalicylic acid: an observational cohort study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cohort Studies; Dose-Response Relationship, | 2011 |
A retrospective study to assess the morbidity associated with transurethral prostatectomy in patients on antiplatelet or anticoagulant drugs.
Topics: Aged; Anticoagulants; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Case-Control Studies; | 2011 |
We should cease offering turp in favour of alternative surgery options for anticoagulated patients.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Humans; Male; Platelet Aggregation Inhibitors; Transu | 2011 |
[Perioperative anti-platelet therapy management--protocol suggestion].
Topics: Aspirin; Blood Loss, Surgical; Clinical Protocols; Clopidogrel; Drug Therapy, Combination; Humans; P | 2011 |
Radical prostatectomy with robot-assisted radical prostatectomy and laparoscopic radical prostatectomy under low-dose aspirin does not significantly increase blood loss.
Topics: Aged; Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Humans; Intraoperative Period; Laparos | 2012 |
Initial experience with aspirin use during robotic radical prostatectomy.
Topics: Adult; Aged; Aspirin; Blood Loss, Surgical; Chi-Square Distribution; Hematocrit; Humans; Laparoscopy | 2012 |
Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Administration Schedule; D | 2012 |
The effects of clopidogrel (Plavix) and other oral anticoagulants on early hip fracture surgery.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; | 2012 |
[Low-dose aspirin doesn't increase surgical bleeding nor transfusion rate in total knee arthroplasty].
Topics: Aged; Arthroplasty, Replacement, Knee; Aspirin; Blood Loss, Surgical; Blood Transfusion; Comorbidity | 2012 |
Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carotid Artery Diseases; Clopidogrel; Drug T | 2012 |
The perioperative management of patients with coronary artery stents: surveying the clinical stakeholders and arriving at a consensus regarding optimal care.
Topics: Adult; Advisory Committees; Alabama; Anesthesiology; Aspirin; Blood Loss, Surgical; Cardiac Catheter | 2012 |
Risk of wound hematoma at carotid endarterectomy under dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, Combination; Endarterectomy, Carotid | 2012 |
Antiplatelet drugs in elective ENT surgery.
Topics: Aspirin; Blood Loss, Surgical; Clinical Protocols; Clopidogrel; Data Collection; Elective Surgical P | 2012 |
Should acetylsalicylic acid (ASA) therapy for prevention of thromboembolic events be stopped prior to surgical extractions?
Topics: Aspirin; Blood Loss, Surgical; Coronary Disease; Female; Humans; Male; Platelet Aggregation Inhibito | 2012 |
Clopidogrel has no effect on mortality from hip fracture.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Aspirin; Bl | 2013 |
Effect of aspirin continuation on blood loss and postoperative morbidity in patients undergoing laparoscopic cholecystectomy or colorectal cancer resection.
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cholecystectomy, Laparoscopic; Colorectal Ne | 2013 |
[Withdrawing the use of acetylsalicyclic acid prior to an operation usually not necessary].
Topics: Aspirin; Blood Loss, Surgical; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation Inhibitors; T | 2003 |
Coronary artery bypass graft surgery in patients with recent exposure to clopidogrel and aspirin therapy.
Topics: Aspirin; Blood Component Transfusion; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Hum | 2003 |
[Evaluation of platelet function using PFA-100].
Topics: Aspirin; Blood Loss, Surgical; Humans; Mass Screening; Platelet Aggregation; Platelet Aggregation In | 2003 |
Effect of haemodilution with diaspirin cross-linked haemoglobin on the oxygen reserve in a rodent model of surgical blood loss.
Topics: Animals; Aspirin; Blood Loss, Surgical; Blood Substitutes; Hematologic Tests; Hemodilution; Hemoglob | 2003 |
The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Blo | 2004 |
[Must platelet aggregation inhibitors be discontinued before surgery?].
Topics: Angiography; Aspirin; Blood Loss, Surgical; Clopidogrel; Humans; Pacemaker, Artificial; Platelet Agg | 2004 |
Aspirin therapy and bleeding during proximal femoral fracture surgery.
Topics: Aged; Aspirin; Blood Loss, Surgical; Case-Control Studies; Femoral Fractures; Humans; Intraoperative | 2004 |
Anticoagulation interruptus: not without risk.
Topics: Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Blood Loss, Surgical; Carotid Arteri | 2004 |
Does clopidogrel increase blood loss following coronary artery bypass surgery?
Topics: Aged; Aspirin; Blood Loss, Surgical; Blood Transfusion; Clopidogrel; Coronary Artery Bypass; Critica | 2004 |
Off-pump coronary artery bypass grafting in a patient with congenital factor V deficiency: report of a case.
Topics: Aspirin; Blood Coagulation Factors; Blood Component Transfusion; Blood Loss, Surgical; Coronary Arte | 2005 |
In-hospital patients exposed to clopidogrel before coronary artery bypass graft surgery: a word of caution.
Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Female; Heparin; Hospital | 2005 |
[Should acetylsalicylic acid be withdrawn prior to surgery?].
Topics: Aspirin; Blood Loss, Surgical; Humans; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Su | 2005 |
[Antiplatelet agents and regional anaesthesia: experience in 130 patients].
Topics: Aged; Aspirin; Autonomic Nerve Block; Blood Loss, Surgical; Blood Vessel Prosthesis Implantation; Cl | 2005 |
Minor oral surgery without stopping daily low-dose aspirin therapy: a study of 51 patients.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, Local; Aspirin; Blood Coagulat | 2005 |
Venous thromboembolism and fractured neck of femur.
Topics: Aged; Aged, 80 and over; Anesthesia; Anticoagulants; Aspirin; Blood Loss, Surgical; Blood Transfusio | 2005 |
The effect of aspirin and warfarin therapy in trabeculectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Blood | 2007 |
The association between aspirin and blood loss in hip fracture patients.
Topics: Aged; Aged, 80 and over; Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Case-Contr | 2006 |
Compatibility of carotid stenting and cardiac surgery.
Topics: Aspirin; Blood Loss, Surgical; Carotid Arteries; Carotid Stenosis; Humans; Platelet Aggregation Inhi | 2006 |
The management of aspirin in transurethral prostatectomy: current practice in the UK.
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Humans; Male; Platelet Aggregation Inhibitor | 2006 |
Low-dose aspirin before spinal surgery: results of a survey among neurosurgeons in Germany.
Topics: Aspirin; Blood Loss, Surgical; Data Collection; Deamino Arginine Vasopressin; Dose-Response Relation | 2007 |
Aspirin use and transrectal ultrasonography-guided prostate biopsy: a national survey.
Topics: Aspirin; Biopsy, Needle; Blood Loss, Surgical; Health Surveys; Humans; Male; Platelet Aggregation In | 2007 |
Aspirin withdrawal prior to invasive medical procedures: a strategy based on thromboembolic and bleeding risk stratification.
Topics: Aspirin; Attitude of Health Personnel; Blood Loss, Surgical; Drug Administration Schedule; Fibrinoly | 2007 |
The effect of platelet-altering medications on bleeding from minor oral surgery procedures.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bl | 2008 |
The Cataract National Dataset electronic multicentre audit of 55,567 operations: antiplatelet and anticoagulant medications.
Topics: Aged; Anesthetics, Local; Anticoagulants; Aspirin; Blood Loss, Surgical; Cataract Extraction; Choroi | 2009 |
Aspirin and clopidogrel use in the perioperative period for non-cardiac surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Drug-Eluting Stents; Humans; Intraoperative Complication | 2008 |
Anticoagulation therapy in glaucoma surgery.
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Glaucoma; Humans; International Normalized Ratio; Oph | 2008 |
[Autologous blood donation, acetylsalicylic acid and risk of bleeding after coronary bypass operation].
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Blood Transfusion, Autologous; Coronary Artery Bypass; Hum | 1994 |
Macroaggregation of platelets in plasma, as distinct from microaggregation in whole blood (and plasma), as determined using optical aggregometry and platelet counting respectively, is specifically impaired following cardiopulmonary bypass in man.
Topics: Aprotinin; Aspirin; Blood; Blood Loss, Surgical; Cardiopulmonary Bypass; Collagen; Hirudins; Humans; | 1994 |
Hemostaseological management of urological operations in patients taking aspirin using the Thrombostat 4000.
Topics: Aspirin; Bleeding Time; Blood Coagulation Tests; Blood Loss, Surgical; Hemostasis, Surgical; Humans; | 1995 |
Shear-induced pathway of platelet function in cardiac surgery.
Topics: Aspirin; Blood Coagulation Tests; Blood Loss, Surgical; Blood Platelets; Cardiopulmonary Bypass; Hem | 1995 |
Preoperative therapy of low-dose aspirin in internal mammary artery bypass operations with and without low-dose aprotinin.
Topics: Aprotinin; Aspirin; Blood Component Transfusion; Blood Loss, Surgical; Drug Therapy, Combination; Em | 1993 |
Thrombelastographic patterns following abdominal aortic surgery.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, General; Antithrombin III; Aorta, Abdomina | 1994 |
Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bandages; Blood Co | 1994 |
Aspirin and bleeding after coronary artery bypass grafting.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Transfusion; Blood Volume; Coronary Artery Byp | 1994 |
Aspirin does not increase homologous blood requirements in elective coronary bypass surgery.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, | 1994 |
Increased blood loss after preoperative NSAID. Retrospective study of 186 hip arthroplasties.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Enoxaparin; Female; Hi | 1993 |
Abnormal peri-operative haemorrhage in asymptomatic patients is not predicted by laboratory testing.
Topics: Aspirin; Blood Loss, Surgical; Hematologic Tests; Humans; Preoperative Care; Risk Factors | 1993 |
Aspirin and post-prostatectomy haemorrhage.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Transfusion; Humans; Male; Middle Aged | 1993 |
Blood loss in long-term aspirin users undergoing transurethral prostatectomy.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Volume; Humans; Male; Middle Aged; Org | 1996 |
Aspirin does not increase allogeneic blood transfusion in reoperative coronary artery surgery.
Topics: Age Factors; Aged; Aminocaproates; Aspirin; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary | 1996 |
[Cataract surgery and anticoagulation--current status].
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Cataract Extraction; Coumarins; Heparin; Humans; Pati | 1996 |
Intraoperative and postoperative bleeding problems in patients taking warfarin, aspirin, and nonsteroidal antiinflammatory agents. A prospective study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bandages; Blood Loss, Surgical; Dermatologic Surgi | 1997 |
Is the management of kidney transplantation influenced by preoperative intake of acetylsalicylic acid?
Topics: Aspirin; Blood Loss, Surgical; Dose-Response Relationship, Drug; Hemostasis, Surgical; Humans; Kidne | 1998 |
Emergency coronary artery bypass grafting (CABG) after failed coronary artery intervention--caution regarding the combined use of aspirin, ticlopidine and abciximab.
Topics: Abciximab; Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; | 1998 |
Glycoprotein IIb/IIIa inhibitors, surgery and bleeding.
Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Loss, Surgical; Co | 1998 |
[Perioperative risk of hemorrhage in urologic operations caused by administration of aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female Urogenital Diseases; | 1998 |
Aspirin intake and bleeding during cataract surgery.
Topics: Aspirin; Blood Loss, Surgical; Cataract Extraction; Eye Hemorrhage; Fibrinolytic Agents; Humans | 1999 |
Aspirin intake and bleeding during cataract surgery.
Topics: Aspirin; Blood Loss, Surgical; Cataract Extraction; Eye Hemorrhage; Follow-Up Studies; Humans; Plate | 1999 |
Safer non-cardiac surgery for patients with coronary artery disease. Preoperative aspirin does increase risk of perioperative bleeding.
Topics: Aspirin; Blood Loss, Surgical; Coronary Disease; Humans; Platelet Aggregation Inhibitors; Risk Facto | 1999 |
Does aspirin affect the outcome of minor cutaneous surgery?
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Cyclooxygenase Inhibitors; Female; Humans; M | 1999 |
Aspirin and surgical bleeding.
Topics: Aspirin; Blood Loss, Surgical; Humans; Platelet Aggregation Inhibitors | 1999 |
Antithrombotic efficacy of a novel murine antihuman factor IX antibody in rats.
Topics: Anesthesia; Animals; Antibodies, Monoclonal; Anticoagulants; Arterial Occlusive Diseases; Aspirin; B | 1999 |
What is the risk of aspirin withdrawal in the surgical patient?
Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Diseases; Humans; Preoperative Care; Risk Factors | 2000 |
Should aspirin be discontinued two weeks before elective surgery?
Topics: Aspirin; Bleeding Time; Blood Loss, Surgical; Elective Surgical Procedures; Half-Life; Humans; Plate | 2000 |
The effect of preoperative aspirin-free interval on red blood cell transfusion requirements in cardiac surgical patients.
Topics: Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Erythrocyte Transfusion; Female; Hemoglobins; | 2002 |
Aprotinin: its role in modifying perioperative blood loss.
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Fibrin Tissue Adhesive; Humans | 1992 |
Aspirin and elective surgical procedures.
Topics: Aged; Aged, 80 and over; Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Platelets; Coronary Art | 1992 |
The effects of preoperative aspirin therapy on platelet function in cardiac surgery.
Topics: Adult; Aged; Aortic Valve Stenosis; Aspirin; Blood Coagulation Tests; Blood Loss, Surgical; Coronary | 1992 |
Surgical bleeding associated with aspirin and nonsteroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Humans | 1992 |
Efficacy, complications, and cost of a comprehensive blood conservation program for cardiac operations.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Blood Transfusion, Autologous; Bloodletting; Cardi | 1992 |
Effects of hypotensive anesthesia, nonsteroidal antiinflammatory drugs, and polymethylmethacrylate on bleeding in total hip arthroplasty patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Hip Prosthesis; Humans; Hypo | 1991 |
Preoperative aspirin therapy and reoperation for bleeding after coronary artery bypass surgery.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Case-Control Studies; Combined Modality Therapy; C | 1991 |
Aspirin and blood loss.
Topics: Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Humans; Premedication; Vascular Patency | 1991 |
The effect of dipyridamole and aspirin on postoperative blood loss after myocardial revascularization.
Topics: Administration, Oral; Aspirin; Blood Coagulation Factors; Blood Loss, Surgical; Blood Transfusion; C | 1989 |
Evaluation of post-cardiopulmonary bypass Sonoclot signatures in patients taking nonsteroidal anti-inflammatory drugs.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Viscosity; Cardiopulmonary Bypass; Evaluation | 1989 |
CABG, aspirin, and transfusion.
Topics: Aspirin; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass; Hemoglobins; Humans; Incid | 1989 |