aspirin has been researched along with Bile Duct Obstruction in 20 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aspirin for metal stents in malignant distal common bile duct obstruction (AIMS) study should determine the efficacy of aspirin in maintaining metal-stent patency in patients with malignant distal CBD obstructive." | 9.34 | Aspirin for metal stent in malignant distal common bile duct obstruction (AIMS): study protocol for a multicenter randomized controlled trial. ( Choi, JH; Choi, YH; Kim, YT; Lee, KJ; Lee, SH; Paik, WH; Ryu, JK; Shin, BS; You, MS, 2020) |
| "In this study the severity of aspirin-induced gastric mucosal damage was investigated in rats with obstructive cholestasis." | 7.70 | Enhancement of aspirin-induced gastric damage by cholestasis in rats. ( Alikhani, Z; Dehpour, AR; Ghaffari, K; Mani, AR; Nowroozi, A; Sabbagh, B; Sadr, S; Sharif, A; Toor Savadkoohi, S; Zeinoddini, M, 1998) |
| "The aspirin for metal stents in malignant distal common bile duct obstruction (AIMS) study should determine the efficacy of aspirin in maintaining metal-stent patency in patients with malignant distal CBD obstructive." | 5.34 | Aspirin for metal stent in malignant distal common bile duct obstruction (AIMS): study protocol for a multicenter randomized controlled trial. ( Choi, JH; Choi, YH; Kim, YT; Lee, KJ; Lee, SH; Paik, WH; Ryu, JK; Shin, BS; You, MS, 2020) |
| "In this study the severity of aspirin-induced gastric mucosal damage was investigated in rats with obstructive cholestasis." | 3.70 | Enhancement of aspirin-induced gastric damage by cholestasis in rats. ( Alikhani, Z; Dehpour, AR; Ghaffari, K; Mani, AR; Nowroozi, A; Sabbagh, B; Sadr, S; Sharif, A; Toor Savadkoohi, S; Zeinoddini, M, 1998) |
| " However, severe and numerous adverse events are associated with vismodegib use." | 2.52 | Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety. ( Ash, MM; Jolly, PS, 2015) |
| "Prednisolone was initiated with clinical and analytical improvement." | 1.56 | Boundaries of a systemic disease: a protean presentation of giant cell arteritis. ( Brotas, V; Camara, L; Mesquita, A; Patrício, C, 2020) |
| "Atypical onset of Kawasaki disease (KD) is a frequent problem leading to diagnostic mistake." | 1.35 | Acute cholestasis: atypical onset of Kawasaki disease. ( Angelone, DF; Ausili, E; De Rosa, G; Focarelli, B; Ranno, O; Schiavino, A; Valentini, P, 2008) |
| "Other signs typical of the Kawasaki disease occurred a few days later and permitted diagnosis." | 1.32 | Painful jaundice revealing Kawasaki disease in a young man. ( Disdier, P; Ene, N; Granel, B; Habib, G; Igual, JP; Serratrice, J; Weiller, PJ, 2004) |
| "Cholestasis is one of the major complications of parenteral nutrition." | 1.30 | The effects of acetylsalicylic acid, interferon-alpha, and vitamin E on prevention of parenteral nutrition-associated cholestasis: an experimental study. ( Atik, E; Demircan, M; Gurer, EI; Gursoy, MH; Mutus, M; Turhan, F; Uguralp, S, 1999) |
| "Cholestasis is a frequent problem in patients on total parenteral nutrition (TPN) therapy." | 1.29 | The choleretic effect of nonsteroidal anti-inflammatory drugs in total parenteral nutrition-associated cholestasis. ( Dinari, G; Hackelman, B; Marcus, H; Nussinovitch, M; Zahavi, I, 1996) |
| "The charts of 238 patients with systemic lupus erythematosus (SLE) were reviewed." | 1.26 | The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature. ( Anuras, S; LaBrecque, DR; Runyon, BA, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 4 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, JH | 2 |
| Lee, KJ | 2 |
| Paik, WH | 2 |
| Park, N | 1 |
| Chun, JW | 1 |
| Lee, SH | 2 |
| Ryu, JK | 2 |
| Kim, YT | 2 |
| You, MS | 1 |
| Choi, YH | 1 |
| Shin, BS | 1 |
| Mesquita, A | 1 |
| Camara, L | 1 |
| Patrício, C | 1 |
| Brotas, V | 1 |
| Gallerani, M | 1 |
| Pala, M | 1 |
| Fabbian, F | 1 |
| De Giorgi, A | 1 |
| Ash, MM | 1 |
| Jolly, PS | 1 |
| Jang, S | 1 |
| Stevens, T | 1 |
| Parsi, MA | 1 |
| Lopez, R | 1 |
| Vargo, JJ | 1 |
| Wong, F | 1 |
| Granel, B | 1 |
| Serratrice, J | 1 |
| Ene, N | 1 |
| Igual, JP | 1 |
| Habib, G | 1 |
| Disdier, P | 1 |
| Weiller, PJ | 1 |
| Polat, A | 1 |
| Emre, MH | 1 |
| Valentini, P | 1 |
| Ausili, E | 1 |
| Schiavino, A | 1 |
| Angelone, DF | 1 |
| Focarelli, B | 1 |
| De Rosa, G | 1 |
| Ranno, O | 1 |
| Kolts, BE | 1 |
| Langfitt, M | 1 |
| Runyon, BA | 1 |
| LaBrecque, DR | 1 |
| Anuras, S | 1 |
| Desgripes, A | 1 |
| Blanc, P | 1 |
| Debray, D | 1 |
| Carbajal, R | 1 |
| Paupe, A | 1 |
| Lenclen, R | 1 |
| Olivier-Martin, M | 1 |
| Nussinovitch, M | 1 |
| Zahavi, I | 1 |
| Marcus, H | 1 |
| Hackelman, B | 1 |
| Dinari, G | 1 |
| Dehpour, AR | 1 |
| Mani, AR | 1 |
| Alikhani, Z | 1 |
| Zeinoddini, M | 1 |
| Toor Savadkoohi, S | 1 |
| Ghaffari, K | 1 |
| Sharif, A | 1 |
| Sabbagh, B | 1 |
| Nowroozi, A | 1 |
| Sadr, S | 1 |
| Demircan, M | 1 |
| Uguralp, S | 1 |
| Mutus, M | 1 |
| Gurer, EI | 1 |
| Atik, E | 1 |
| Turhan, F | 1 |
| Gursoy, MH | 1 |
| Meyer, MI | 1 |
| Kuhn, M | 1 |
| Bühler, H | 1 |
| Bertschinger, P | 1 |
| Lai, MY | 1 |
| Sung, JL | 1 |
| Lin, WS | 1 |
| How, SW | 1 |
| Yu, JY | 1 |
| Wang, TH | 1 |
| Chen, DS | 1 |
| Gal'perin, EI | 1 |
| Tatishvili, GG | 1 |
| Akhaladze, GG | 1 |
| Sakevarashvili, GR | 1 |
| Nasirov, FN | 1 |
| Aref'ev, AE | 1 |
| Monte, MJ | 1 |
| Esteller, A | 1 |
| Jimenez, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Aspirin on Patency of Metal Stent in Malignant Distal Bile Duct Obstruction[NCT03279809] | 52 participants (Actual) | Interventional | 2017-10-12 | Terminated (stopped due to One grade 4 adverse event (AE) and common (47.2%) grade 3 AEs) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aspirin and Bile Duct Obstruction
| Article | Year |
|---|---|
Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety.
Topics: Aged; Anilides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, | 2015 |
Liver and kidney diseases.
Topics: Acetaminophen; Anemia, Sickle Cell; Animals; Aspirin; Cholestasis; Cysts; Glomerulonephritis, IGA; G | 2002 |
Biochemical and morphological study of the liver injury induced by drugs and chemicals.
Topics: Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Halothan | 1979 |
2 trials available for aspirin and Bile Duct Obstruction
| Article | Year |
|---|---|
Acetylsalicylic acid for metal stent in malignant distal common bile duct obstruction: A randomized controlled trial.
Topics: Aspirin; Bile Duct Neoplasms; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Humans; | 2022 |
Aspirin for metal stent in malignant distal common bile duct obstruction (AIMS): study protocol for a multicenter randomized controlled trial.
Topics: Aspirin; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Common Bile Duct; Double-Blin | 2020 |
15 other studies available for aspirin and Bile Duct Obstruction
| Article | Year |
|---|---|
Boundaries of a systemic disease: a protean presentation of giant cell arteritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cholestasis; Cough; Diagnosis, Differential; Drug | 2020 |
Acute cholestasis as uncommon onset of Kawasaki disease: a case report.
Topics: Adult; Aspirin; Child; Child, Preschool; Cholestasis; Edema; Fever; Humans; Male; Mucocutaneous Lymp | 2020 |
Aspirin Use Is Associated With Reduced Risk of Occlusion of Metallic Biliary Stents.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biliary Tract Surgical Procedures; Cholestas | 2017 |
Painful jaundice revealing Kawasaki disease in a young man.
Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cholestasis; Humans; I | 2004 |
Effects of melatonin or acetylsalicylic acid on gastric oxidative stress after bile duct ligation in rats.
Topics: Animals; Aspirin; Bile Ducts; Catalase; Cholestasis; Disease Models, Animal; Glutathione Peroxidase; | 2006 |
Acute cholestasis: atypical onset of Kawasaki disease.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Cholestasis; Diagnosis, Diff | 2008 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv | 1984 |
The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature.
Topics: Adolescent; Adult; Aged; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; | 1980 |
[Inaugural acute cholestasis of Kawasaki disease].
Topics: Acute Disease; Adolescent; Aspirin; Cholestasis; Humans; Immunization, Passive; Male; Mucocutaneous | 1996 |
The choleretic effect of nonsteroidal anti-inflammatory drugs in total parenteral nutrition-associated cholestasis.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Bile Acids and Salts; | 1996 |
Enhancement of aspirin-induced gastric damage by cholestasis in rats.
Topics: Animals; Aspirin; Bile Ducts; Cholestasis; Disease Models, Animal; Gastric Mucosa; Irritants; Laparo | 1998 |
The effects of acetylsalicylic acid, interferon-alpha, and vitamin E on prevention of parenteral nutrition-associated cholestasis: an experimental study.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspart | 1999 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas | 1999 |
[Disorders of organic hemodynamics of the liver and their correction in suppurative cholangitis].
Topics: Acute Disease; Animals; Aprotinin; Ascorbic Acid; Aspirin; Cholangitis; Cholestasis; Dextrans; Dipyr | 1991 |
Acetylsalicylate-induced cholestasis, unrelated to biliary bile acid excretion, in the rabbit.
Topics: Analgesics; Animals; Aspirin; Bicarbonates; Bile; Bile Acids and Salts; Chlorides; Cholestasis; Lysi | 1988 |