Page last updated: 2024-10-23

aspirin and Bacterial Disease

aspirin has been researched along with Bacterial Disease in 38 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Soluble aspirin was given by mouth in therapeutic doses in a double-blind trial to malnourished infants and young children with gastroenteritis and dehydration."9.05Reduction by aspirin of intestinal fluid-loss in acute childhood gastroenteritis. ( Burke, V; Gracey, M, 1980)
"Soluble aspirin given by mouth in divided dosage decreased intestinal fluid loss in infants and young children with acute gastroenteritis."9.05Aspirin in acute gastroenteritis: a clinical and microbiological study. ( Burke, V; Gracey, M; Phadke, MA; Raut, SK; Singh, B, 1984)
" In this review, we discuss the possible repurposing of drugs approved for cardiovascular diseases, such as β-blockers, angiotensin converting enzyme inhibitors (ACE-Is), angiotensin II receptor blockers (ARBs), statins, aspirin, cardiac glycosides and low-molecular-weight heparins (LMWHs)."5.05Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage? ( Camera, M; Castiglioni, L; Gelosa, P; Sironi, L, 2020)
"Soluble aspirin was given by mouth in therapeutic doses in a double-blind trial to malnourished infants and young children with gastroenteritis and dehydration."5.05Reduction by aspirin of intestinal fluid-loss in acute childhood gastroenteritis. ( Burke, V; Gracey, M, 1980)
"Soluble aspirin given by mouth in divided dosage decreased intestinal fluid loss in infants and young children with acute gastroenteritis."5.05Aspirin in acute gastroenteritis: a clinical and microbiological study. ( Burke, V; Gracey, M; Phadke, MA; Raut, SK; Singh, B, 1984)
"Viral pericarditis is the most common cause of acute pericarditis and it is typically responsive to aspirin or nonsteroidal anti-inflammatory drugs."4.95Tuberculous and Infectious Pericarditis. ( Chang, SA, 2017)
" Bleeding is the most common complication observed after prostate biopsy, but the use of aspirin or nonsteroidal anti-inflammatory drugs is not an absolute contraindication to prostate biopsy."4.89Complications of prostate biopsy. ( Anastasiadis, A; Antoniewicz, A; Cordeiro, E; De Reijke, T; Dimitriadis, G; Zapała, L, 2013)
"The clinical characteristics of idiopathic nasal polyposis in children (11 males and nine females; median: 12 years; range: 8-15 years) were very similar to those observed in adults (median: 50 years), in particular the relation to asthma (ten of 20 cases) and aspirin intolerance (two Fernand-Widal syndromes of 20 cases)."3.70[Does idiopathic naso-sinusal polyposis exist in children?]. ( Coffinet, L; Derelle, J; Jankowski, R; Pialoux, R, 1999)
"Nasal polyps are as common as adult onset asthma and unilateral polyps require histological examination."2.42Nasal polyps. ( Drake-Lee, AB, 2004)
"Severe influenza virus (IV) infections still represent a major challenge to public health."1.56The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections. ( Deinhardt-Emmer, S; Ehrhardt, C; Gieselmann, L; Haupt, KF; Hrincius, ER; Ludwig, S; Niemann, S; Preugschas, HF; van Krüchten, A; Wilden, JJ, 2020)
"Antiphospholipid syndrome is an autoimmune disorder characterized by the occurrence of venous and arterial thrombosis, as well as morbidity in pregnancy, in the presence of anti-phospholipid antibodies."1.42Elevated levels of antibodies against phosphatidylserine/prothrombin complex and/or cardiolipin associated with infection and recurrent purpura in a child: a forme fruste of antiphospholipid syndrome? ( Igarashi, T; Inaba, M; Katagiri, I; Kawana, S; Kinoshita, Y; Mayumi, N, 2015)
"Aspirin was effective at 100-500 microg concentration against all isolates."1.36Antibacterial effect of NSAIDS on clinical isolates of urinary tract infection and diabetic foot infection. ( Akhter, T; Aziz, M; Baqai, R, 2010)
"Seven children with juvenile rheumatoid arthritis had a syndrome characterized by hemorrhage and neurologic, hepatic, hematologic, and metabolic manifestations."1.27Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection. ( Griscelli, C; Hadchouel, M; Prieur, AM, 1985)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's4 (10.53)18.2507
2000's8 (21.05)29.6817
2010's6 (15.79)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Gelosa, P1
Castiglioni, L1
Camera, M1
Sironi, L1
Wilden, JJ1
van Krüchten, A1
Gieselmann, L1
Hrincius, ER1
Deinhardt-Emmer, S1
Haupt, KF1
Preugschas, HF1
Niemann, S1
Ludwig, S1
Ehrhardt, C1
Chang, SA1
Lapponi, MJ1
Carestia, A1
Landoni, VI1
Rivadeneyra, L1
Etulain, J1
Negrotto, S1
Pozner, RG1
Schattner, M1
Anastasiadis, A1
Zapała, L1
Cordeiro, E1
Antoniewicz, A1
Dimitriadis, G1
De Reijke, T1
Vale, PF1
Fenton, A1
Brown, SP1
Kinoshita, Y1
Mayumi, N1
Inaba, M1
Igarashi, T1
Katagiri, I1
Kawana, S1
Akhter, T1
Baqai, R1
Aziz, M1
Thompson, SG1
Higgins, JP1
Riedel, W1
Lang, U1
Oetjen, U1
Schlapp, U1
Shibata, M1
ABU-NASSAR, HJ1
YOW, EM1
ALEXANDER, JK1
LEWIS, JM1
Okada, Y1
Minakami, H1
Tomomasa, T1
Kato, M1
Inoue, Y1
Kozawa, K1
Kimura, H1
Morikawa, A1
Drake-Lee, AB1
Burgner, D1
Harnden, A1
Allegaert, K1
Anderson, BJ1
Cossey, V1
Holford, NH1
Burke, V3
Gracey, M3
Pini, M1
Potí, R1
Dettori, AG1
Korman, SH1
Berant, M1
Alon, U1
Phadke, MA1
Raut, SK1
Singh, B1
Zychowicz, C1
Hockertz, S1
Heckenberger, R1
Alexander, RE1
Zambito, RF1
Pialoux, R1
Coffinet, L1
Derelle, J1
Jankowski, R1
Sielenkämper, AW1
Yu, P1
Eichelbrönner, O1
MacDonald, T1
Martin, CM1
Chin-Yee, IH1
Sibbald, WJ1
Howell, TH1
Ridker, PM1
Ajani, UA1
Hennekens, CH1
Christen, WG1
Cabanac, M1
Govorochin, EA1
Marshak, AM1
Douglas, RG1
Terezhalmy, GT1
Bowen, LL1
Rye, LA1
Weiner, CP1
Grzesik, J1
Rzymełka, S1
Hadchouel, M1
Prieur, AM1
Griscelli, C1
Gault, MH1
Blennerhassett, J1
Muehrcke, RC1
Van Reken, D1
Strauss, A1
Hernandez, A1
Feigin, RD1
Sugawa, C1
Lucas, CE1
Rosenberg, BF1
Riddle, JM1
Walt, AJ1
De Launey, WE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000500]Phase 30 participants Interventional1981-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for aspirin and Bacterial Disease

ArticleYear
Repurposing of drugs approved for cardiovascular diseases: Opportunity or mirage?
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Conv

2020
Tuberculous and Infectious Pericarditis.
    Cardiology clinics, 2017, Volume: 35, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal

2017
Complications of prostate biopsy.
    Expert review of anticancer therapy, 2013, Volume: 13, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Biopsy; Ciprofloxacin; Drug

2013
Nasal polyps.
    Hospital medicine (London, England : 1998), 2004, Volume: 65, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bacterial Infections; Drug Hypersensitivit

2004
Kawasaki disease: what is the epidemiology telling us about the etiology?
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2005, Volume: 9, Issue:4

    Topics: Air Pollutants; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Child; Commu

2005
[Thrombotic thrombopenic purpura. Description of 2 cases and review of the literature].
    Recenti progressi in medicina, 1982, Volume: 73, Issue:4

    Topics: Adult; Aspirin; Autoimmune Diseases; Bacterial Infections; Blood Transfusion; Dextrans; Dipyridamole

1982
Review: prostaglandins in diarrheal states.
    Israel journal of medical sciences, 1981, Volume: 17, Issue:12

    Topics: Aspirin; Bacterial Infections; Child; Cholera Toxin; Colonic Diseases; Cyclic AMP; Diarrhea; Dinopro

1981
Pharmacotherapeutics in urgent dental care.
    Dental clinics of North America, 1986, Volume: 30, Issue:3

    Topics: Aminophenols; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anxiety; Aspirin;

1986
Diagnosis and management of thromboembolic disease during pregnancy.
    Clinical obstetrics and gynecology, 1985, Volume: 28, Issue:1

    Topics: Acute Disease; Aspirin; Bacterial Infections; Female; Heparin; Humans; Ovary; Phlebography; Plethysm

1985
[Ototoxic factors requiring consideration in the diagnosis of occupational hearing loss].
    Medycyna pracy, 1985, Volume: 36, Issue:2

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Bacterial Infections; Carbon Disulfide; Carbo

1985

Trials

3 trials available for aspirin and Bacterial Disease

ArticleYear
Reduction by aspirin of intestinal fluid-loss in acute childhood gastroenteritis.
    Lancet (London, England), 1980, Jun-21, Volume: 1, Issue:8182

    Topics: Aspirin; Bacterial Infections; Body Weight; Clinical Trials as Topic; Dehydration; Diarrhea, Infanti

1980
Aspirin in acute gastroenteritis: a clinical and microbiological study.
    Journal of pediatric gastroenterology and nutrition, 1984, Volume: 3, Issue:5

    Topics: Acute Disease; Aeromonas; Aspirin; Bacterial Infections; Child, Preschool; Clinical Trials as Topic;

1984
Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians.
    Journal of the American College of Cardiology, 2001, Volume: 37, Issue:2

    Topics: Adult; Aged; Aspirin; Bacterial Infections; beta Carotene; Cause of Death; Coronary Disease; Double-

2001

Other Studies

25 other studies available for aspirin and Bacterial Disease

ArticleYear
The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: A549 Cells; Antiviral Agents; Aspirin; Bacterial Infections; Drug Combinations; Epithelial Cells; Ge

2020
Regulation of neutrophil extracellular trap formation by anti-inflammatory drugs.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:3

    Topics: Acidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Asp

2013
Limiting damage during infection: lessons from infection tolerance for novel therapeutics.
    PLoS biology, 2014, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Adhesion; Bacterial Infections; Bacteria

2014
Elevated levels of antibodies against phosphatidylserine/prothrombin complex and/or cardiolipin associated with infection and recurrent purpura in a child: a forme fruste of antiphospholipid syndrome?
    Dermatology online journal, 2015, Jul-15, Volume: 21, Issue:7

    Topics: Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Aspirin; Autoantibodies; Bacterial Infection

2015
Antibacterial effect of NSAIDS on clinical isolates of urinary tract infection and diabetic foot infection.
    Pakistan journal of pharmaceutical sciences, 2010, Volume: 23, Issue:1

    Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial In

2010
How should meta-regression analyses be undertaken and interpreted?
    Statistics in medicine, 2002, Jun-15, Volume: 21, Issue:11

    Topics: Adrenergic beta-Antagonists; Aminoglycosides; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-S

2002
Inhibition of oxygen radical formation by methylene blue, aspirin, or alpha-lipoic acid, prevents bacterial-lipopolysaccharide-induced fever.
    Molecular and cellular biochemistry, 2003, Volume: 247, Issue:1-2

    Topics: Animals; Antioxidants; Aspirin; Bacterial Infections; Brain; Catalase; Endotoxins; Female; Fever; Fo

2003
PRIMARY STAPHYLOCOCCAL PERICARDITIS COMPLICATING CARDIOTOMY: A REPORT OF A CASE WITH A NOTE ON INTRAPERICARDIAL METHICILLIN THERAPY.
    Annals of internal medicine, 1964, Volume: 60

    Topics: Aspirin; Bacterial Infections; Cardiac Surgical Procedures; Methicillin; Penicillins; Pericarditis;

1964
Serum procalcitonin concentration in patients with Kawasaki disease.
    The Journal of infection, 2004, Volume: 48, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Autoimmune Diseases; Bacterial Infections; C-React

2004
Limited predictability of amikacin clearance in extreme premature neonates at birth.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:1

    Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bact

2006
Studies with enterotoxigenic microorganisms: effects of candidate antidiarrhoeals in experimental animals in vivo.
    Journal of pediatric gastroenterology and nutrition, 1984, Volume: 3, Issue:4

    Topics: Aluminum Hydroxide; Animals; Antidiarrheals; Aspirin; Bacterial Infections; Charcoal; Chlorpromazine

1984
[Therapeutic procedures in recurrent respiratory tract infections in children].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Aug-15, Volume: 34, Issue:16

    Topics: Albuterol; Anti-Bacterial Agents; Aspirin; Bacterial Infections; Child; Child, Preschool; Humans; In

1981
Treatment of an acute bacterial infection with a combination of acetylsalicylic acid/ibuprofen and interferon gamma.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Colony Count, Micro

1996
Eleven myths of dentoalveolar surgery.
    Journal of the American Dental Association (1939), 1998, Volume: 129, Issue:9

    Topics: Alcoholic Beverages; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Blood C

1998
Dentoalveolar surgery.
    Journal of the American Dental Association (1939), 1998, Volume: 129, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Humans; Pain, Postoperative;

1998
[Does idiopathic naso-sinusal polyposis exist in children?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bacterial

1999
Diaspirin cross-linked Hb and norepinephrine prevent the sepsis-induced increase in critical O(2) delivery.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Animals; Aspirin; Bacterial Infections; Biological Availability; Blood Pressure; Hemodilution; Hemog

2000
[Fever and evolution].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1978, Volume: 54, Issue:13-16

    Topics: Animals; Aspirin; Bacterial Infections; Behavior, Animal; Biological Evolution; Birds; Body Temperat

1978
[Chemotherapy of purulent infections].
    Sovetskaia meditsina, 1977, Issue:3

    Topics: Anti-Bacterial Agents; Aspirin; Bacterial Infections; Humans; Suppuration

1977
Influenza: the disease and its complications.
    Hospital practice, 1976, Volume: 11, Issue:12

    Topics: Amantadine; Aspirin; Bacterial Infections; Bronchitis; Central Nervous System Diseases; Cross Infect

1976
Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection.
    The Journal of pediatrics, 1985, Volume: 106, Issue:4

    Topics: Acute Disease; Arthritis, Juvenile; Aspirin; Bacterial Infections; Child; Child, Preschool; Coma; Di

1985
Analgesic nephropathy. A clinicopathologic study using electron microscopy.
    The American journal of medicine, 1971, Volume: 51, Issue:6

    Topics: Adult; Aspirin; Autopsy; Bacterial Infections; Basement Membrane; Beta-Globulins; Biopsy; Collagen;

1971
Infectious pericarditis in children.
    The Journal of pediatrics, 1974, Volume: 85, Issue:2

    Topics: Adenoviridae Infections; Adolescent; Ampicillin; Aortic Aneurysm; Aspirin; Bacterial Infections; Chi

1974
Differential topography of acute erosive gastritis due to trauma or sepsis, ethanol and aspirin.
    Gastrointestinal endoscopy, 1973, Volume: 19, Issue:3

    Topics: Abdominal Injuries; Acute Disease; Aspirin; Bacterial Infections; Ethanol; Gastritis; Gastrointestin

1973
Eczema: Causes and management.
    Drugs, 1973, Volume: 6, Issue:5

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Infective Agents; Aspirin; Bacterial Infectio

1973