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aspirin and Autosomal Hemophilia A

aspirin has been researched along with Autosomal Hemophilia A in 50 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The following 13 recommendations stand out: 1) Do not delay the administration of factor after trauma; 2) do not use fresh frozen plasma or cryoprecipitate; 3) do not use desmopressin in case of hematuria; 4) do not change the product in the first 50 prophylaxis exposures; 5) do not interrupt immunotolerance; 6) do not administer aspirin or NSAIDs; 7) do not administer intramuscular injections; 8) do not do routine radiographs of the joint in case of acute hemarthrosis; 9) Do not apply closed casts for fractures; 10) do not discourage the performance of physical activities; 11) do not deny surgery to a patient with an inhibitor; 12) do not perform instrumental deliveries in fetuses with hemophilia; 13) do not use factor IX (FIX) in patients with hemophilia B with inhibitor and a history of anaphylaxis after administration of FIX."5.05'Do not Do' Recommendations in Hemophilia. ( Alvarez-Roman, MT; De la Corte-Rodriguez, H; Jimenez-Yuste, V; Martin-Salces, M; Rodriguez-Merchan, EC, 2020)
" Aspirin prophylaxis begun for suspected rheumatic fever led to compartment syndromes of all four extremities, which resolved with high-dose FVIII and surgical decompression."4.81Acquired anti-FVIII inhibitors in children. ( Moraca, RJ; Ragni, MV, 2002)
" A prolonged bleeding time is observed: (1) in thrombopathic thrombocytopenia, which may be (a) hereditary or (b) acquired, as in the immune types or from depression of bone marrow, and (2) athrombocytopenically, as in von Willebrand's disease, Glanzmann's thrombasthenia, or from aspirin intolerance."3.65The bleeding time as a test of hemostatic function. ( Quick, AJ, 1975)
"The six patients with Haemophilia A ranged in severity from moderately to mildly affected."2.69Cardiac surgery and catheterization in patients with haemophilia. ( MacKinlay, N; Renisson, F; Rickard, K; Taper, J, 2000)
"The fatalistic attitude of hemophiliacs toward hepatitis is discussed, along with admonitions to avoid the use of aspirin, alcohol, and buttock injections."2.35Orthodontics and dentistry for the hemophilic patient. ( Grossman, RC, 1975)
"A 72-year-old man, on treatment for prostate cancer, attended the emergency department with his 2nd episode of spontaneous extensive bruising and haematomas."1.43Aspirin unmasking acquired haemophilia A in a patient with prostate cancer. ( Keane, F; Khan, AZ; Murad, F; Okiro, JO, 2016)
"A retrospective study of 58 adult hemophilia patients (≥35 years) attending Mayo Comprehensive Hemophilia Center between 1 January 2006 and 15 October 2009 were reviewed."1.37Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients. ( Lim, MY; Pruthi, RK, 2011)
"Anticoagulation therapy and factor VIII deficiency were found to be responsible for the intramural hemorrhage in five patients (83%) and one patient, respectively."1.36Spontaneous intramural hematoma of the small intestine. ( Carkman, S; Ergüney, S; Korman, U; Ozben, V; Pekmezci, S; Saribeyoğlu, K; Somuncu, E, 2010)
"Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for the bleeding time."1.26Prolonged bleeding time in children and young adults with hemophilia. ( Buchanan, GR; Holtkamp, CA, 1980)
"The case is presented of a hemophilia carrier, also affected by von Willebrand's disease, who underwent aortic valve replacement."1.25Open-heart surgery in von Willebrand's disease. ( Aris, A; Gale, H; Hussey, CV; Lepley, D; Pisciotta, AV, 1975)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199040 (80.00)18.7374
1990's1 (2.00)18.2507
2000's3 (6.00)29.6817
2010's5 (10.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
De la Corte-Rodriguez, H1
Rodriguez-Merchan, EC1
Alvarez-Roman, MT1
Martin-Salces, M1
Jimenez-Yuste, V1
Aguilar, C1
Okiro, JO1
Khan, AZ1
Keane, F1
Murad, F1
Carkman, S1
Ozben, V1
Saribeyoğlu, K1
Somuncu, E1
Ergüney, S1
Korman, U1
Pekmezci, S1
Lim, MY1
Pruthi, RK1
Franchini, M1
Coppola, A1
NATHAN, AS1
RUBIN, BJ1
ROSEN, MB1
Ferrario, C1
Renders, F1
Cairoli, A1
Vuffray, A1
Spertini, O1
Angelillo-Scherrer, A1
Quick, AJ9
Buchanan, GR1
Holtkamp, CA1
Meade, TW1
MacKinlay, N1
Taper, J1
Renisson, F1
Rickard, K1
Moraca, RJ1
Ragni, MV1
Mustard, JF1
Perry, DW1
Kinlough-Rathbone, RL1
Packham, MA1
Ts'ao, CH1
Smith, C1
Staven, P1
Evensen, SA1
Aris, A1
Pisciotta, AV1
Hussey, CV1
Gale, H1
Lepley, D1
Grossman, RC1
Hawkins, C1
Jenkins, CS1
Meyer, D1
Dreyfus, MD1
Larrieu, MJ1
Weiss, HJ1
Hussey, HH2
Robinson, HJ1
Granda, JL1
George, JN1
Kasper, CK2
Rapaport, SI2
Binder, RA1
Durocher, J1
Mielke, H1
Green, D1
Forbes, CD1
Barr, RD1
McNicol, GP1
Douglas, AS1
Benson, VM1
Kaneshiro, MM1
Mielke, CH2
Toskes, PP1
Wagger, GM1
Raskin, HF1
Attar, S1
Bodenbender, RH1
Heimansohn, H1
Nakasawa, S1
Yamada, Z1
Yamada, K1
Praga, C1
Cortellaro, M1
Veltkamp, JJ1
Willemin, M1
Gaston, LW1
Britten, AF1
Cronberg, S1
Neumark, E2

Reviews

10 reviews available for aspirin and Autosomal Hemophilia A

ArticleYear
'Do not Do' Recommendations in Hemophilia.
    Cardiovascular & hematological disorders drug targets, 2020, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Factors; Deamino Arginine Vasopr

2020
Antithrombotic therapy in a patient with mild haemophilia A and atrial fibrillation: case report and brief review of the literature.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Disease Management; Dronedar

2015
Atherothrombosis in von Willebrand disease: an analysis of the literature and implications for clinical management.
    Seminars in thrombosis and hemostasis, 2012, Volume: 38, Issue:2

    Topics: Adult; Aged; Aspirin; Atherosclerosis; Cardiac Surgical Procedures; Coronary Artery Disease; Hemophi

2012
Management of an acute coronary syndrome in a patient with severe haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2007, Volume: 13, Issue:6

    Topics: Acute Coronary Syndrome; Antifibrinolytic Agents; Aspirin; Clopidogrel; Fibrinolytic Agents; Hemophi

2007
Haemostatic function, arterial disease and the prevention of arterial thrombosis.
    Bailliere's clinical haematology, 1994, Volume: 7, Issue:3

    Topics: Adult; Aged; Anticoagulants; Arteries; Aspirin; Blood Coagulation Factors; Cardiovascular Diseases;

1994
Acquired anti-FVIII inhibitors in children.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2002, Volume: 8, Issue:1

    Topics: Adolescent; Aspirin; Autoantibodies; Autoimmune Diseases; Child; Child, Preschool; Compartment Syndr

2002
Orthodontics and dentistry for the hemophilic patient.
    American journal of orthodontics, 1975, Volume: 68, Issue:4

    Topics: Anesthesia, Dental; Aspirin; Blood Platelets; Buttocks; Factor VIII; Gingival Hemorrhage; Hemophilia

1975
Von Willebrand's disease--diagnostic criteria.
    Blood, 1968, Volume: 32, Issue:4

    Topics: Adenine Nucleotides; Aspirin; Blood Coagulation Tests; Blood Platelets; gamma-Globulins; Genetics, M

1968
Hemophilia.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Aminocaproates; Aspirin; Factor IX; Factor VIII; Hemophilia A; Hemophilia B; Humans; Liver; Spleen

1974
Genetic aspects of hemostasis. A review.
    Thrombosis et diathesis haemorrhagica, 1968, Nov-15, Volume: 20, Issue:1

    Topics: Adolescent; Afibrinogenemia; Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Pl

1968

Trials

3 trials available for aspirin and Autosomal Hemophilia A

ArticleYear
Cardiac surgery and catheterization in patients with haemophilia.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2000, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Aortic Valve; Aspirin; Cardiac Catheterization; Coronary Angiography; Coron

2000
Bleeding times and platelet aggregation after analgesics in hemophilia.
    Annals of internal medicine, 1972, Volume: 77, Issue:2

    Topics: Acetaminophen; Adenosine Diphosphate; Adolescent; Adult; Analgesics; Aspirin; Blood Coagulation Fact

1972
Treatment of pain in hemophilia. Effect of drugs on bleeding time.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:3

    Topics: Administration, Oral; Analgesics; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Platele

1974

Other Studies

37 other studies available for aspirin and Autosomal Hemophilia A

ArticleYear
Aspirin unmasking acquired haemophilia A in a patient with prostate cancer.
    BMJ case reports, 2016, Sep-08, Volume: 2016

    Topics: Aged; Aspirin; Contusions; Hematoma; Hemophilia A; Humans; Male; Partial Thromboplastin Time; Platel

2016
Spontaneous intramural hematoma of the small intestine.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2010, Volume: 16, Issue:2

    Topics: Adult; Aged; Anticoagulants; Aspirin; Hematoma; Hemophilia A; Humans; Intestinal Diseases; Intestine

2010
Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Disease Management; Hemophil

2011
CONSERVATIVE TREATMENT OF A LARGE RADICULAR CYST OF THE MANDIBLE IN A PATIENT WITH SEVERE HEMOPHILIA. REPORT OF A CASE.
    Oral surgery, oral medicine, and oral pathology, 1964, Volume: 17

    Topics: Aspirin; Blood Chemical Analysis; Blood Transfusion; Dentigerous Cyst; Diagnosis, Differential; Drai

1964
The Duke bleeding time.
    American journal of clinical pathology, 1967, Volume: 47, Issue:4

    Topics: Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Cold Temperature; Hemophilia A; Hemor

1967
Prolonged bleeding time in children and young adults with hemophilia.
    Pediatrics, 1980, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Aspirin; Bleeding Time; Blood Platelets; Child; Child, Preschool; Hemophilia A; H

1980
Factors responsible for ADP-induced release reaction of human platelets.
    The American journal of physiology, 1975, Volume: 228, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Citrates; Fibrinogen; gamma-Globulins; Hemop

1975
Potentiation of platelet aggregation by heat-precipitated plasma proteins.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:1

    Topics: Adenosine Diphosphate; Aspirin; Blood Proteins; Chemical Precipitation; Collagen; Epinephrine; Fibri

1978
[Prolonged bleeding time--has the patient been taking acetylsalicylic acid?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jun-10, Volume: 96, Issue:16

    Topics: Aspirin; Blood Platelets; Female; Hemophilia A; Hemostasis; Humans; Male; Prothrombin Time

1976
Open-heart surgery in von Willebrand's disease.
    The Journal of thoracic and cardiovascular surgery, 1975, Volume: 69, Issue:2

    Topics: Aortic Valve Stenosis; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Transfusion; Cardi

1975
The bleeding time as a test of hemostatic function.
    American journal of clinical pathology, 1975, Volume: 64, Issue:1

    Topics: Aspirin; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulatio

1975
Pain in haemophilia.
    Lancet (London, England), 1973, May-05, Volume: 1, Issue:7810

    Topics: Aspirin; Gastrointestinal Hemorrhage; Hemophilia A; Humans; Indomethacin; Male; Pain; Phenylbutazone

1973
Pain in haemophilia.
    Lancet (London, England), 1973, May-05, Volume: 1, Issue:7810

    Topics: Acetaminophen; Analgesics; Aspirin; Codeine; Cryotherapy; Gastrointestinal Hemorrhage; Headache; Hem

1973
Willebrand factor and ristocetin. I. Mechanism of rustocetin-induced platelet aggregation.
    British journal of haematology, 1974, Volume: 28, Issue:4

    Topics: Adenosine Diphosphate; Albumins; Aspirin; Carbon Radioisotopes; Chromatography, Gel; Dose-Response R

1974
Aspirin and the blood.
    Lancet (London, England), 1966, Oct-08, Volume: 2, Issue:7467

    Topics: Anemia, Aplastic; Aspirin; Gastric Mucosa; Hematemesis; Hemophilia A; Humans; Substance-Related Diso

1966
Editorial: Aspirin can be dangerous.
    JAMA, 1974, Apr-29, Volume: 228, Issue:5

    Topics: Aspirin; Blood Coagulation; Hemophilia A; Humans; Peptic Ulcer; Platelet Adhesiveness

1974
Prostaglandins in synovial inflammatory disease.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Arthritis; Aspirin; Hemophilia A; Humans; Indomethacin; Inflammation; Prostaglandins; Synovial Fluid

1974
Editorial: Aspirin and aspirin products.
    JAMA, 1974, Dec-02, Volume: 230, Issue:9

    Topics: Aspirin; Drug Labeling; Hemophilia A; Hemorrhagic Disorders; Humans; Pain; Peptic Ulcer; United Stat

1974
Direct assessment of platelet adhesion to glass: a study of the forces of interaction and the effects of plasma and serum factors, platelet function, and modification of the glass surface.
    Blood, 1972, Volume: 40, Issue:6

    Topics: Adenosine Diphosphate; Adsorption; Anticoagulants; Aspirin; Blood Coagulation; Blood Coagulation Fac

1972
Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin.
    Journal of clinical pathology, 1972, Volume: 25, Issue:3

    Topics: Adenosine; Animals; Aspirin; Blood Cell Count; Cattle; Densitometry; Factor VIII; Fibrinogen; Goats;

1972
Intracranial hemorrhage in hemophilia.
    JAMA, 1971, Sep-06, Volume: 217, Issue:10

    Topics: Adult; Aspirin; Blood Transfusion; Cerebral Hemorrhage; Hemophilia A; Humans; Male

1971
Marihuana "study" critique.
    JAMA, 1971, Sep-06, Volume: 217, Issue:10

    Topics: Adult; Aspirin; Blood Transfusion; Cerebral Hemorrhage; Hemophilia A; Humans; Male

1971
Aspirin, platelets, and bleeding.
    The Journal of pediatrics, 1971, Volume: 79, Issue:5

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Hemophilia A; Humans

1971
Acetylsalicylic acid as a diagnostic aid in hemostasis.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:4

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Female; Hemophilia A; Hemophilia B; Huma

1967
Bleeding time after aspirin in disorders of intrinsic clotting.
    The New England journal of medicine, 1969, Nov-06, Volume: 281, Issue:19

    Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Transfusion; Factor VIII; Factor XI Defic

1969
Coagulation defects in undiagnosed recurrent gastrointestinal bleeding.
    Annals of surgery, 1970, Volume: 172, Issue:1

    Topics: Adult; Aged; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulation Test

1970
Aspirin hazard.
    JAMA, 1971, Feb-22, Volume: 215, Issue:8

    Topics: Aspirin; Child; Hemophilia A; Humans; Male; Oral Hemorrhage; Tooth Extraction

1971
Aspirin and hemophilia.
    Journal of the American Dental Association (1939), 1971, Volume: 83, Issue:5

    Topics: Aspirin; Hemophilia A; Oral Hemorrhage; Tooth Extraction

1971
[Effect of aspirin on the blood platelets in children].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1971, Volume: 75, Issue:10

    Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Coagulati

1971
Effect of aspirin on platelet aggregation and bleeding time in haemophilia and von Willebrand's disease.
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Adenosine Diphosphate; Administration, Oral; Aspirin; Blood Platelets; Epinephrine; Hemophilia A; Hu

1971
Aspirin and bleeders.
    The New England journal of medicine, 1970, Aug-20, Volume: 283, Issue:8

    Topics: Adolescent; Aspirin; Blood Coagulation; Hemophilia A; Humans; Male

1970
Use of aspirin or acetaminophen in hemophilia.
    The New England journal of medicine, 1970, May-28, Volume: 282, Issue:22

    Topics: Acetaminophen; Aspirin; Blood Coagulation Tests; Blood Platelets; Hemophilia A; Humans; Male

1970
Hemophilia and aspirin.
    JAMA, 1970, Sep-07, Volume: 213, Issue:10

    Topics: Adult; Aspirin; Factor XIII; Hemophilia A; Humans; Male; Plasma

1970
No aspirin for hemophiliacs.
    The New England journal of medicine, 1971, Jan-28, Volume: 284, Issue:4

    Topics: Aspirin; Blood Coagulation Factors; Blood Transfusion; Hemophilia A; Humans; Tooth Extraction

1971
[Acetylsalycylic acid and hemostasis].
    Lakartidningen, 1971, Mar-29, Volume: 68

    Topics: Aspirin; Blood Platelets; Hemophilia A; Hemorrhage; Humans

1971
What to avoid in the treatment of pain in hemophilia.
    Bibliotheca haematologica, 1966, Volume: 26

    Topics: Aspirin; Hemophilia A; Humans; Immobilization; Pain; Pain Management

1966
What to avoid in the treatment of pain in hemophilia.
    Bibliotheca haematologica, 1966, Volume: 26

    Topics: Aspirin; Hemophilia A; Humans; Immobilization; Pain; Pain Management

1966