aspirin has been researched along with Attachment Loss, Periodontal in 12 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the feasibility of periodontal mechanical therapy for chronic periodontitis and coronary heart disease patients with low dose of aspirin." | 9.24 | [Bleeding control of periodontal mechanical therapy for patients taking aspirin]. ( Ding, F; Duan, XQ; Han, X; Liu, DY; Lyu, YL; Xuan, W, 2017) |
| "To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome." | 7.96 | Omega-3 Fatty Acids and Low-Dose Aspirin in the Treatment of Periodontitis and Metabolic Syndrome: Case Report. ( Andere, NMRB; Araujo, CF; Dos Santos, NC; Miguel, MMV; Santamaria, MP; Van Dyke, T; Westphal, MRA, 2020) |
| "To investigate the feasibility of periodontal mechanical therapy for chronic periodontitis and coronary heart disease patients with low dose of aspirin." | 5.24 | [Bleeding control of periodontal mechanical therapy for patients taking aspirin]. ( Ding, F; Duan, XQ; Han, X; Liu, DY; Lyu, YL; Xuan, W, 2017) |
| " The aim of this study was to evaluate the efficacy of systemic administration of omega-3 polyunsaturated fatty acids plus low-dose aspirin as an adjunctive treatment to regenerative therapy of furcation defects." | 5.15 | The efficacy of host response modulation therapy (omega-3 plus low-dose aspirin) as an adjunctive treatment of chronic periodontitis (clinical and biochemical study). ( Elkhouli, AM, 2011) |
| "To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome." | 3.96 | Omega-3 Fatty Acids and Low-Dose Aspirin in the Treatment of Periodontitis and Metabolic Syndrome: Case Report. ( Andere, NMRB; Araujo, CF; Dos Santos, NC; Miguel, MMV; Santamaria, MP; Van Dyke, T; Westphal, MRA, 2020) |
| "Low-dose aspirin has been hypothesized as being a potential host modulatory agent for periodontitis treatment." | 3.81 | Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012. ( Demmer, RT; Ioannou, AL; Kotsakis, GA; Michalowicz, BS; Thai, A, 2015) |
| " Ligatures were removed after 10 days of periodontitis induction and all groups were submitted to treatment with aspirin (Asp) (30 mg/kg), clopidogrel (Clop) (75 mg/kg) or NaCl 0." | 3.80 | Clopidogrel enhances periodontal repair in rats through decreased inflammation. ( Coimbra, LS; Graves, DT; Rossa, C; Spolidorio, LC; Steffens, JP, 2014) |
| "To measure the effects on periodontitis, ligatures were placed around first molars, and aspirin (Asp, 30 mg/kg) or clopidogrel (Clo, 75 mg/kg) was given intragastrically once daily for 15 days." | 3.77 | Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats. ( Coimbra, LS; Gerlach, RF; Guimarães, MR; Herrera, BS; Muscará, MN; Rossa, C; Spolidorio, DM; Spolidorio, LC, 2011) |
| " Correlation analysis suggested that there was a negative correlation between clinical attachment loss and duration of aspirin intake but the clinical attachment loss was not significantly different in the two dosage groups." | 2.77 | Association between long-term aspirin use and periodontal attachment level in humans: a cross-sectional investigation. ( Faizuddin, M; Korla, N; Swamy, S; Tarannum, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Castro Dos Santos, NC | 1 |
| Andere, NMRB | 2 |
| Araujo, CF | 2 |
| de Marco, AC | 1 |
| Kantarci, A | 2 |
| Van Dyke, TE | 2 |
| Santamaria, MP | 2 |
| Dos Santos, NC | 1 |
| Miguel, MMV | 1 |
| Westphal, MRA | 1 |
| Van Dyke, T | 1 |
| Bali, SK | 1 |
| Madaiah, H | 1 |
| Dharmapalan, J | 1 |
| Janarthanam, S | 1 |
| Tarannum, F | 2 |
| Shiloah, J | 1 |
| Bland, PS | 1 |
| Scarbecz, M | 1 |
| Patters, MR | 1 |
| Stein, SH | 1 |
| Tipton, DA | 1 |
| Coimbra, LS | 2 |
| Steffens, JP | 1 |
| Rossa, C | 2 |
| Graves, DT | 1 |
| Spolidorio, LC | 2 |
| Kotsakis, GA | 1 |
| Thai, A | 1 |
| Ioannou, AL | 1 |
| Demmer, RT | 1 |
| Michalowicz, BS | 1 |
| Ding, F | 1 |
| Lyu, YL | 1 |
| Xuan, W | 1 |
| Liu, DY | 1 |
| Duan, XQ | 1 |
| Han, X | 1 |
| El-Sharkawy, H | 1 |
| Aboelsaad, N | 1 |
| Eliwa, M | 1 |
| Darweesh, M | 1 |
| Alshahat, M | 1 |
| Hasturk, H | 1 |
| Guimarães, MR | 1 |
| Gerlach, RF | 1 |
| Muscará, MN | 1 |
| Spolidorio, DM | 1 |
| Herrera, BS | 1 |
| Elkhouli, AM | 1 |
| Faizuddin, M | 1 |
| Korla, N | 1 |
| Swamy, S | 1 |
| Drouganis, A | 1 |
| Hirsch, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Omega-3 Polyunsaturated Fatty Acids Daily Supplementation Plus Low-dose Aspirin as Adjunct to Full-mouth Periodontal Ultrasonic Debridement for the Treatment of Chronic Periodontitis in Type 2 Diabetics: Randomized Clinical Trial[NCT02800252] | 75 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | |||
| Evaluation of Omega-3 Polyunsaturated Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Generalized Aggressive Periodontitis: Randomized Controlled Clinical Trial[NCT03093207] | Phase 2/Phase 3 | 34 participants (Actual) | Interventional | 2017-05-15 | Completed | ||
| Evaluation of Omega-3 Polyunsaturated Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Generalized Aggressive Periodontitis: Randomized Controlled Clinical Trial[NCT03093246] | Phase 2/Phase 3 | 38 participants (Actual) | Interventional | 2017-05-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Evaluate the difference between baseline and 6 months CAL measures. CAL: distance from bottom of sulcus/pocket to the cement-enamel junction (CEJ). The CEJ will be identified by careful probe on cervical area. (NCT03093207)
Timeframe: Baseline, 3 and 6 months
| Intervention | mm (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 5.29 | 4.73 | 4.97 |
| Test Group | 5.5 | 4.64 | 4.64 |
Evaluate the difference between baseline and 6 months BoP measures. BoP: bleeding that is induced by gentle probing of the sulcus/pocket. (NCT03093207)
Timeframe: Baseline, 3 and 6 months
| Intervention | percentage of sites with BoP (Number) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 100 | 100 | 64.7 |
| Test Group | 100 | 76.47 | 64.7 |
Evaluate the difference between baseline and 6 months PB measures. PB: distance from the bottom of sulcus/pocket to gingival margin. (NCT03093207)
Timeframe: Baseline, 3 and 6 months
| Intervention | mm (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 5.14 | 3.76 | 3.94 |
| Test Group | 5.17 | 4.08 | 4 |
Evaluate the difference between baseline and 6 months BoP measures (NCT03093246)
Timeframe: Baseline, 3 and 6 months
| Intervention | percentage of sites with BoP (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 54.11 | 33.27 | 31.77 |
| Test Group | 44.58 | 27.41 | 26.17 |
Evaluate the difference between baseline and 6 months CAL measures. (NCT03093246)
Timeframe: Baseline, 3 and 6 months
| Intervention | milimeters (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 3.94 | 3.58 | 3.59 |
| Test Group | 4.01 | 3.65 | 3.64 |
Evaluate the difference between baseline and 6 months PD measures. (NCT03093246)
Timeframe: Baseline, 3 and 6 months
| Intervention | milimeters (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Control Group | 3.88 | 3.38 | 3.37 |
| Test Group | 3.74 | 3.26 | 3.25 |
6 trials available for aspirin and Attachment Loss, Periodontal
| Article | Year |
|---|---|
Omega-3 PUFA and aspirin as adjuncts to periodontal debridement in patients with periodontitis and type 2 diabetes mellitus: Randomized clinical trial.
Topics: Aspirin; Chronic Periodontitis; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Periodontal | 2020 |
The effect of long-term aspirin intake on the outcome of non-surgical periodontal therapy in smokers: a double-blind, randomized pilot study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Periodontitis; Dental Plaque | 2014 |
[Bleeding control of periodontal mechanical therapy for patients taking aspirin].
Topics: Aspirin; Chronic Periodontitis; Contraindications; Coronary Disease; Dental Scaling; Hemorrhage; Hem | 2017 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Per | 2010 |
The efficacy of host response modulation therapy (omega-3 plus low-dose aspirin) as an adjunctive treatment of chronic periodontitis (clinical and biochemical study).
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Transplantation; | 2011 |
Association between long-term aspirin use and periodontal attachment level in humans: a cross-sectional investigation.
Topics: Aspirin; Chi-Square Distribution; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Female; Humans | 2012 |
6 other studies available for aspirin and Attachment Loss, Periodontal
| Article | Year |
|---|---|
Omega-3 Fatty Acids and Low-Dose Aspirin in the Treatment of Periodontitis and Metabolic Syndrome: Case Report.
Topics: Aspirin; Chronic Periodontitis; Fatty Acids, Omega-3; Gingival Crevicular Fluid; Humans; Metabolic S | 2020 |
Effect of systemic long-term, low-dose aspirin on periodontal status and soluble CD14 in gingival crevicular fluid: a case-control study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Chronic Periodontitis; Denta | 2018 |
Clopidogrel enhances periodontal repair in rats through decreased inflammation.
Topics: Alveolar Bone Loss; Animals; Aspirin; Cell Count; Chemokine CCL5; Chemokine CXCL12; Clopidogrel; Inf | 2014 |
Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012.
Topics: Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Diabe | 2015 |
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
Topics: Alveolar Bone Loss; Animals; Aspirin; Blood Platelets; Bone Density; Bone Regeneration; Clopidogrel; | 2011 |
Low-dose aspirin therapy and periodontal attachment loss in ex- and non-smokers.
Topics: Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; | 2001 |