Page last updated: 2024-10-23

aspirin and Atheroma

aspirin has been researched along with Atheroma in 37 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"This prospective randomized controlled, open-labeled trial, with blinded end point evaluation (PROBE design) tested superiority of aspirin 75 to 150 mg/d plus clopidogrel 75 mg/d (A+C) over warfarin therapy (international normalized ratio 2-3) in patients with ischemic stroke, transient ischemic attack, or peripheral embolism with plaque in the thoracic aorta>4 mm and no other identified embolic source."9.19Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. ( Amarenco, P; Cohen, AA; Davis, S; Donnan, GA; Heiss, WD; Jones, EF; Kaste, M; Laouénan, C; Macleod, M; Young, D, 2014)
"Although clopidogrel is a frequently used antiplatelet medication to treat and prevent atherothrombotic disease, clinicians must balance its clinical effectiveness with the potential side effect of bleeding."9.12Risk Factors for Bleeding and Clinical Ineffectiveness Associated With Clopidogrel Therapy: A Comprehensive Meta-Analysis. ( Duong, K; Eadon, MT; Fekete, K; Kenneally, A; Milway, E; Nguyen, KA; Oh, H; Schleyer, TK; Whipple, EC; Yoo, R, 2021)
" Among current therapies, low-dose aspirin has been shown to reduce cardiovascular thrombosis."7.96A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis. ( Burchiel, S; Eaton, RP; Schade, DS, 2020)
"These results suggest that low dose aspirin reduces early atherosclerosis, while inhibition of COX-2 by meloxicam is not associated with an increase in atherosclerotic plaque size in this mouse model."7.80Aspirin but not meloxicam attenuates early atherosclerosis in apolipoprotein E knockout mice. ( Afek, A; Arber, N; Aroch, I; Eisenberg, O; Finkelstein, A; George, J; Kazanov, D; Kraus, S; Naumov, I; Shapira, S, 2014)
"Hydrogen sulfide (H(2)S) is a novel gaseous mediator that plays important roles in atherosclerosis."7.78Effect of S-aspirin, a novel hydrogen-sulfide-releasing aspirin (ACS14), on atherosclerosis in apoE-deficient mice. ( Fan, Y; Gu, T; Guo, C; Sparatore, A; Wang, C; Wu, D; Zhang, A; Zhang, H, 2012)
"Targeting platelet-mediated thrombus formation with dual antiplatelet therapy comprising acetylsalicylic acid and a P2Y12 antagonist is the current mainstay for management of ACS."6.50Targeting therapy to the fibrin-mediated pathophysiology of acute coronary syndrome. ( White, H, 2014)
"8 years with 10-75% coronary artery stenosis, as assessed by coronary computed tomography angiography, were randomly assigned to sarpogrelate 300 mg/day plus aspirin 100 mg/day (SPG + ASA group) or aspirin 100 mg/day alone (ASA group) for 6 months."5.24Effect of sarpogrelate, a selective 5-HT ( Chun, EJ; Han, SJ; Hur, JH; Jang, HC; Kang, DK; Kim, HJ; Kim, KM; Lee, DH; Lee, JE; Lim, S; Min, SH; Oh, TJ, 2017)
"This prospective randomized controlled, open-labeled trial, with blinded end point evaluation (PROBE design) tested superiority of aspirin 75 to 150 mg/d plus clopidogrel 75 mg/d (A+C) over warfarin therapy (international normalized ratio 2-3) in patients with ischemic stroke, transient ischemic attack, or peripheral embolism with plaque in the thoracic aorta>4 mm and no other identified embolic source."5.19Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. ( Amarenco, P; Cohen, AA; Davis, S; Donnan, GA; Heiss, WD; Jones, EF; Kaste, M; Laouénan, C; Macleod, M; Young, D, 2014)
"Although clopidogrel is a frequently used antiplatelet medication to treat and prevent atherothrombotic disease, clinicians must balance its clinical effectiveness with the potential side effect of bleeding."5.12Risk Factors for Bleeding and Clinical Ineffectiveness Associated With Clopidogrel Therapy: A Comprehensive Meta-Analysis. ( Duong, K; Eadon, MT; Fekete, K; Kenneally, A; Milway, E; Nguyen, KA; Oh, H; Schleyer, TK; Whipple, EC; Yoo, R, 2021)
"We investigated whether combination of glenzocimab, a GPVI inhibitor, with aspirin and ticagrelor provides additional antithrombotic effects, as GPVI has a critical role in atherothrombosis but minimal involvement in hemostasis."4.31Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy. ( Alenazy, FO; Brady, P; Connolly, DL; Harbi, MH; Hargreaves, O; Harrison, P; Jandrot-Perrus, M; Kalia, N; Kavanagh, DP; Kirchhof, P; Mangin, PH; Nicolson, PLR; Price, J; Slater, A; Thomas, MR; Tiwari, A; Watson, SP, 2023)
" Among current therapies, low-dose aspirin has been shown to reduce cardiovascular thrombosis."3.96A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis. ( Burchiel, S; Eaton, RP; Schade, DS, 2020)
"The initial EROSION study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion) demonstrated that patients with acute coronary syndrome caused by plaque erosion might be stabilized with aspirin and ticagrelor without stenting for ≤1 month."3.85EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report. ( Bryniarski, K; Hou, J; Hu, S; Jang, IK; Jia, H; Lee, H; Li, L; Liu, H; Ma, L; Sugiyama, T; Wang, C; Xing, L; Xu, M; Yamamoto, E; Yu, B; Zhang, S; Zhu, Y, 2017)
"Within this retrospective observational spontaneous clinical study 44 patients (31 males and 13 females) all presenting stable coronary artery disease were evaluated; 25 subjects were treated with only acetylsalicylic acid and/or clopidogrel in association with statins (standard therapeutic protocol) while for the other 18 subjects the standard therapeutic protocol was integrated with Arnica comp."3.83Effects of Arnica comp.-Heel® on reducing cardiovascular events in patients with stable coronary disease. ( Bianchi, M; Di Nardo, V; Fioranelli, M; Roccia, MG, 2016)
"In mice deficient of apolipoprotein E (Apoe-/-), aspirin (20, 50 mg/kg/day) suppressed the progression of atherosclerosis in aortic roots and increased the plaque stability in carotid atherosclerotic plaques induced by collar-placement."3.83Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo. ( Chen, Y; Li, P; Li, QZ; Liang, WJ; Ma, H; Ma, ZM; Peng, QS; Wang, F; Wang, SX; Yang, JJ; Zhang, Y, 2016)
"These results suggest that low dose aspirin reduces early atherosclerosis, while inhibition of COX-2 by meloxicam is not associated with an increase in atherosclerotic plaque size in this mouse model."3.80Aspirin but not meloxicam attenuates early atherosclerosis in apolipoprotein E knockout mice. ( Afek, A; Arber, N; Aroch, I; Eisenberg, O; Finkelstein, A; George, J; Kazanov, D; Kraus, S; Naumov, I; Shapira, S, 2014)
"Hydrogen sulfide (H(2)S) is a novel gaseous mediator that plays important roles in atherosclerosis."3.78Effect of S-aspirin, a novel hydrogen-sulfide-releasing aspirin (ACS14), on atherosclerosis in apoE-deficient mice. ( Fan, Y; Gu, T; Guo, C; Sparatore, A; Wang, C; Wu, D; Zhang, A; Zhang, H, 2012)
"Aspirin is an effective antiplatelet agent for the treatment of carotid atherosclerosis."3.11Dengzhan Shengmai capsule versus Aspirin in the treatment of carotid atherosclerotic plaque: A single-centre, non-inferiority, prospective, randomised controlled trial. ( Jin, J; Liu, Y; Qu, L; Shen, X; Wu, J; Zou, S, 2022)
"Aspirin response test was evaluated 1 hour after aspirin intake using multiplate platelet function analyzer, and carotid ultrasonography has been performed to determine carotid intima-media thickness (CIMT) and the presence of carotid plaque."2.87The Relationship Between Aspirin Resistance and Carotid Imaging in Young Patients With ST-Segment Elevated Myocardial Infarction: A Cross-Sectional Study. ( Bulut, U; Demir, AR; Kalayci, B; Karakurt, H; Karakurt, ST; Serbest, NG; Somuncu, MU, 2018)
"Twenty patients with ≥50 % angiographic stenosis of the SFA had blood drawn just proximal to the lesion and from a contralateral site free of disease."2.78Increased local cytokine production at culprit superficial femoral artery plaques. ( Adams, JE; Ashikaga, T; Bertges, DJ; Dauerman, HL; Donaldson, CW; Elgharib, NZ; Mueller, EL; Prabhu, W; Schneider, DJ, 2013)
"Targeting platelet-mediated thrombus formation with dual antiplatelet therapy comprising acetylsalicylic acid and a P2Y12 antagonist is the current mainstay for management of ACS."2.50Targeting therapy to the fibrin-mediated pathophysiology of acute coronary syndrome. ( White, H, 2014)
"Patients with type 2 diabetes mellitus are characterized by increased incidence of cardiovascular events and enhanced thromboxane-dependent platelet activation."2.47TP receptor activation and inhibition in atherothrombosis: the paradigm of diabetes mellitus. ( Davì, G; Mucci, L; Santilli, F, 2011)
"Atherothrombosis, an atherosclerotic plaque disruption condition with superimposed thrombosis, is the underlying cause of cardiovascular episodes."1.72Atherothrombosis-on-Chip: A Site-Specific Microfluidic Model for Thrombus Formation and Drug Discovery. ( Adelnia, H; Akther, F; Fallahi, H; Nguyen, NT; Phan, HP; Ta, HT; Tran, HDN; Zhang, J, 2022)
" The aim of our study was to investigate if the Syk inhibitor fostamatinib could be repurposed as an antiplatelet drug, either alone or in combination with conventional antiplatelet therapy."1.72Antithrombotic Effects of Fostamatinib in Combination with Conventional Antiplatelet Drugs. ( Alenazy, FO; Harbi, MH; Nicolson, PLR; Smith, CW; Thomas, MR; Tiwari, A; Watson, SP, 2022)
"Recent studies suggested protruding thrombus and atheroma after stent placement could be a substrate for subsequent adverse ischemic events."1.48Potent effect of prasugrel on acute phase resolution of intra-stent athero-thrombotic burden after percutaneous intervention to acute coronary syndrome. ( Hirata, KI; Kijima, Y; Kozuki, A; Masano, T; Nagoshi, R; Otake, H; Shibata, H; Shinke, T; Shite, J; Takeshige, R; Tsukiyama, Y; Yanaka, KI, 2018)
"It is a marker of atherosclerotic plaque burden and the strongest independent predictor of future myocardial infarction and mortality."1.46Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring. ( Chan, J; Chow, CK; Hamilton-Craig, CR; Jelinek, VM; Liew, GY; Younger, JF, 2017)
"Consecutive patients with atherosclerotic plaque detected by coronary CT angiography were enrolled in our study from September 2013 to December 2014, grouped as <50% stenosis and ≥ 50% stenosis."1.42[Influence of coronary CT angiography findings on prevention strategies of coronary artery disease]. ( Dai, R; Gao, Y; Hou, Z; Jiang, S; Li, Z; Liu, K; Lü, B; Ren, X; Wang, Z; Yin, W, 2015)
"Stroke is a second cause of mortality worldwide and a leading cause of acquired disability in adults."1.38[Ulcerated plaques of the aorta as a cause of ischaemic stroke]. ( Hoffman, P; Kowalski, M; Michałowska, I; Rybicka, J, 2012)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's28 (75.68)24.3611
2020's9 (24.32)2.80

Authors

AuthorsStudies
Akther, F1
Zhang, J1
Tran, HDN1
Fallahi, H1
Adelnia, H1
Phan, HP1
Nguyen, NT1
Ta, HT1
Harbi, MH2
Smith, CW1
Alenazy, FO2
Nicolson, PLR2
Tiwari, A2
Watson, SP2
Thomas, MR2
Shen, X1
Zou, S1
Jin, J1
Liu, Y1
Wu, J1
Qu, L1
Kavanagh, DP1
Price, J1
Brady, P1
Hargreaves, O1
Harrison, P1
Slater, A1
Connolly, DL1
Kirchhof, P1
Kalia, N1
Jandrot-Perrus, M1
Mangin, PH1
Belcaro, G2
Cesarone, MR2
Scipione, C2
Scipione, V2
Dugall, M2
Shu, H1
Peterzan, P1
Corsi, M1
Luzzi, R1
Hosoi, M1
Feragalli, B2
Cotellese, R2
Hu, S2
Maione, C1
Nguyen, KA1
Eadon, MT1
Yoo, R1
Milway, E1
Kenneally, A1
Fekete, K1
Oh, H1
Duong, K1
Whipple, EC1
Schleyer, TK1
Schade, DS1
Burchiel, S1
Eaton, RP1
Oggero, S1
de Gaetano, M1
Marcone, S1
Fitzsimons, S1
Pinto, AL1
Ikramova, D1
Barry, M1
Burke, D1
Montero-Melendez, T1
Cooper, D1
Burgoyne, T1
Belton, O1
Norling, LV1
Brennan, EP1
Godson, C1
Perretti, M1
Hamilton-Craig, CR1
Chow, CK1
Younger, JF1
Jelinek, VM1
Chan, J1
Liew, GY1
Soehnlein, O1
Xing, L1
Yamamoto, E1
Sugiyama, T1
Jia, H1
Ma, L1
Wang, C2
Zhu, Y1
Li, L1
Xu, M1
Liu, H1
Bryniarski, K1
Hou, J1
Zhang, S1
Lee, H1
Yu, B1
Jang, IK1
Tsukiyama, Y1
Kozuki, A1
Shinke, T1
Otake, H1
Kijima, Y1
Masano, T1
Nagoshi, R1
Shibata, H1
Takeshige, R1
Yanaka, KI1
Shite, J1
Hirata, KI1
Somuncu, MU1
Demir, AR1
Karakurt, H1
Serbest, NG1
Kalayci, B1
Bulut, U1
Karakurt, ST1
Weingärtner, O1
Schulze, PC1
Möbius-Winkler, S1
Chan, NC1
Weitz, JI2
Fazio, S1
Brigo, F1
Storti, M1
Lochner, P1
Tezzon, F1
Nardone, R1
Bakri, SJ1
Luqman, A1
Pathik, B1
Chandrasekaran, K1
Amarenco, P1
Davis, S1
Jones, EF1
Cohen, AA1
Heiss, WD1
Kaste, M1
Laouénan, C1
Young, D1
Macleod, M1
Donnan, GA1
Kraus, S1
Naumov, I1
Shapira, S1
Kazanov, D1
Aroch, I1
Afek, A1
Eisenberg, O1
George, J1
Arber, N1
Finkelstein, A1
Okura, H1
Kataoka, T1
Yoshiyama, M1
Yoshikawa, J1
Yoshida, K1
Lewszuk, AJ1
Postuła, M1
Madycki, G1
Staszkiewicz, W1
Opolski, G1
Eberhardt, A1
Amato, B1
Compagna, R1
Amato, M1
Gallelli, L1
de Franciscis, S1
Serra, R1
Li, Z1
Lü, B1
Wang, Z1
Liu, K1
Hou, Z1
Gao, Y1
Yin, W1
Ren, X1
Jiang, S1
Dai, R1
Fioranelli, M1
Bianchi, M1
Roccia, MG1
Di Nardo, V1
Yang, JJ1
Li, P1
Wang, F1
Liang, WJ1
Ma, H1
Chen, Y1
Ma, ZM1
Li, QZ1
Peng, QS1
Zhang, Y1
Wang, SX1
Sasaki, K1
Ueno, T1
Lee, DH1
Chun, EJ1
Hur, JH1
Min, SH1
Lee, JE1
Oh, TJ1
Kim, KM1
Jang, HC1
Han, SJ1
Kang, DK1
Kim, HJ1
Lim, S1
Philipp, S1
Böse, D1
Wijns, W1
Marso, SP1
Schwartz, RS1
König, A1
Lerman, A1
Garcia-Garcia, HM1
Serruys, PW1
Erbel, R1
Santilli, F1
Mucci, L1
Davì, G1
Masumura, Y1
Ueda, Y1
Matsuo, K1
Akazawa, Y1
Nishio, M1
Hirata, A1
Kashiwase, K1
Nemoto, T1
Kashiyama, T1
Wada, M1
Muller, JE1
Kodama, K1
Rybicka, J1
Kowalski, M1
Michałowska, I1
Hoffman, P1
Reinhart, WH1
Zhang, H1
Guo, C1
Zhang, A1
Fan, Y1
Gu, T1
Wu, D1
Sparatore, A1
Donaldson, CW1
Schneider, DJ1
Bertges, DJ1
Adams, JE1
Elgharib, NZ1
Mueller, EL1
Prabhu, W1
Ashikaga, T1
Dauerman, HL1
White, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Plaque Erosion: A New in Vivo Diagnosis and Paradigm Shift in the Treatment of Patients With Acute Coronary Syndrome[NCT02041650]Phase 4250 participants (Anticipated)Interventional2014-08-31Completed
Prevention of New Vascular Events in Patients With Brain Infarction or Peripheral Embolism and Thoracic Aortic Plaques ≥ 4 mm in Thickness in the Aortic Arch or Descending Aortic Upstream to the Embolized Artery[NCT00235248]Phase 3350 participants (Actual)Interventional2002-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aspirin and Atheroma

ArticleYear
Risk Factors for Bleeding and Clinical Ineffectiveness Associated With Clopidogrel Therapy: A Comprehensive Meta-Analysis.
    Clinical and translational science, 2021, Volume: 14, Issue:2

    Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Dual Anti-Platelet Therapy; Hemorrhage; Huma

2021
[Atherothrombosis : Novel therapeutic strategies].
    Herz, 2018, Volume: 43, Issue:2

    Topics: Animals; Anticoagulants; Aspirin; Carrier Proteins; Clinical Trials as Topic; Humans; Hydroxymethylg

2018
Antithrombotic Agents.
    Circulation research, 2019, Volume: 124, Issue:3

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Clinical Trials a

2019
TP receptor activation and inhibition in atherothrombosis: the paradigm of diabetes mellitus.
    Internal and emergency medicine, 2011, Volume: 6, Issue:3

    Topics: Aspirin; Diabetes Complications; Diabetes Mellitus, Type 2; Humans; Plaque, Atherosclerotic; Platele

2011
Targeting therapy to the fibrin-mediated pathophysiology of acute coronary syndrome.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2014, Volume: 20, Issue:5

    Topics: Acute Coronary Syndrome; Aspirin; Blood Coagulation; Fibrin; Humans; Plaque, Atherosclerotic; Platel

2014

Trials

6 trials available for aspirin and Atheroma

ArticleYear
Dengzhan Shengmai capsule versus Aspirin in the treatment of carotid atherosclerotic plaque: A single-centre, non-inferiority, prospective, randomised controlled trial.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Aspirin; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cholesterol, LDL; Drugs, Chinese H

2022
The Relationship Between Aspirin Resistance and Carotid Imaging in Young Patients With ST-Segment Elevated Myocardial Infarction: A Cross-Sectional Study.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2018, Volume: 24, Issue:8

    Topics: Adult; Aspirin; Carotid Artery Diseases; Carotid Intima-Media Thickness; Drug Resistance; Female; Hu

2018
Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques.
    Stroke, 2014, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aorta, Thoracic; Aortic Diseases; Aspirin; Brain Ischemia;

2014
Aterofisiol(®) in carotid plaque evolution.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Adult; Aged; Aspirin; Carotid Stenosis; Dietary Supplements; Double-Blind Method; Endarterectomy, Ca

2015
Effect of sarpogrelate, a selective 5-HT
    Atherosclerosis, 2017, Volume: 257

    Topics: Adult; Aged; Ankle Brachial Index; Anti-Inflammatory Agents; Aspirin; Biomarkers; Computed Tomograph

2017
Increased local cytokine production at culprit superficial femoral artery plaques.
    Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:3

    Topics: Aspirin; CD40 Ligand; Clopidogrel; Constriction, Pathologic; Female; Femoral Artery; Humans; Hydroxy

2013

Other Studies

26 other studies available for aspirin and Atheroma

ArticleYear
Atherothrombosis-on-Chip: A Site-Specific Microfluidic Model for Thrombus Formation and Drug Discovery.
    Advanced biology, 2022, Volume: 6, Issue:7

    Topics: Aspirin; Drug Discovery; Humans; Microfluidics; Plaque, Atherosclerotic; Reproducibility of Results;

2022
Antithrombotic Effects of Fostamatinib in Combination with Conventional Antiplatelet Drugs.
    International journal of molecular sciences, 2022, Jun-23, Volume: 23, Issue:13

    Topics: Aminopyridines; Animals; Aspirin; Fibrinolytic Agents; Humans; Mice; Morpholines; Oxazines; Plaque,

2022
Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy.
    Journal of thrombosis and haemostasis : JTH, 2023, Volume: 21, Issue:11

    Topics: Acute Coronary Syndrome; Animals; Aspirin; Fibrinolytic Agents; Humans; Mice; Plaque, Atheroscleroti

2023
Delayed progression of atherosclerosis and cardiovascular events in asymptomatic patients with atherosclerotic plaques: 3-year prevention with the supplementation with Pycnogenol®+Centellicum®.
    Minerva cardioangiologica, 2020, Volume: 68, Issue:1

    Topics: Aged; Aspirin; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Centella; D

2020
Central cardiovascular calcifications: supplementation with Pycnogenol® and Centellicum®: variations over 12 months.
    Minerva cardioangiologica, 2020, Volume: 68, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Centella; Coronary Artery Disease; Dietary Supplements; Disease Ma

2020
A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2020, Volume: 26, Issue:7

    Topics: Aged; Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Humans; Plaque, Atherosclerotic; Pr

2020
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity.
    Journal of extracellular vesicles, 2021, Volume: 10, Issue:6

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Cytokines; Endothelial Cells; Extracellular Vesicles; Hea

2021
Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring.
    The Medical journal of Australia, 2017, Oct-16, Volume: 207, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asymptomatic Diseases; Coronary Artery Disea

2017
EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report.
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:12

    Topics: Acute Coronary Syndrome; Adenosine; Adult; Aspirin; Coronary Angiography; Coronary Artery Disease; C

2017
Potent effect of prasugrel on acute phase resolution of intra-stent athero-thrombotic burden after percutaneous intervention to acute coronary syndrome.
    Journal of cardiology, 2018, Volume: 72, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Blood Platelets; Clopidogrel; Drug Therapy, Combination; Fem

2018
[Optical Coherence Tomography in ST-Elevation Myocardial Infarction].
    Deutsche medizinische Wochenschrift (1946), 2018, Volume: 113, Issue:13

    Topics: Aged, 80 and over; Aspirin; Coronary Angiography; Coronary Artery Disease; Diagnosis, Differential;

2018
Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis.
    Circulation research, 2019, Volume: 124, Issue:3

    Topics: Anticholesteremic Agents; Aspirin; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Re

2019
Aspirin for primary prevention of atherothrombotic vascular events: how much "conclusive" is "conclusive?".
    The American journal of cardiology, 2013, Sep-15, Volume: 112, Issue:6

    Topics: Aspirin; Dose-Response Relationship, Drug; Humans; Plaque, Atherosclerotic; Platelet Aggregation Inh

2013
Is carotid ultrasound necessary in the evaluation of the asymptomatic Hollenhorst plaque?
    Ophthalmology, 2013, Volume: 120, Issue:12

    Topics: Arterioles; Aspirin; Asymptomatic Diseases; Carotid Arteries; Carotid Stenosis; Endarterectomy, Caro

2013
Aspirin but not meloxicam attenuates early atherosclerosis in apolipoprotein E knockout mice.
    The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Aspirin; Atherosclerosis; Cyclo

2014
Long-term prognostic impact of the attenuated plaque in patients with acute coronary syndrome.
    Heart and vessels, 2016, Volume: 31, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Corona

2016
Evaluation of aspirin resistance and the presence of unstable carotid plaque in patients undergoing carotid endarterectomy.
    Kardiologia polska, 2015, Volume: 73, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Carotid Stenosis; Endarterectomy, Carotid;

2015
[Influence of coronary CT angiography findings on prevention strategies of coronary artery disease].
    Zhonghua yi xue za zhi, 2015, Sep-01, Volume: 95, Issue:33

    Topics: Aspirin; Cholesterol; Coronary Angiography; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-C

2015
Effects of Arnica comp.-Heel® on reducing cardiovascular events in patients with stable coronary disease.
    Minerva cardioangiologica, 2016, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Dr

2016
Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo.
    Oncotarget, 2016, Aug-16, Volume: 7, Issue:33

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Aspirin; Atherosclerosis; Cells

2016
[CHARISMA study].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Jun-20, Volume: 74 Suppl 4 Pt 1

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Embolism; Female; Humans; Male; Middle Aged; Plaque,

2016
Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry.
    European heart journal, 2010, Volume: 31, Issue:2

    Topics: Aged; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Diabetic Angiopathies; Dyslipidemias

2010
Frequency and location of yellow and disrupted coronary plaques in patients as detected by angioscopy.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Angioscopy; Aspirin; Clopidogrel; Coronary Artery Disease; Disease Pr

2011
[Ulcerated plaques of the aorta as a cause of ischaemic stroke].
    Kardiologia polska, 2012, Volume: 70, Issue:5

    Topics: Acenocoumarol; Aspirin; Echocardiography; Foramen Ovale, Patent; Humans; Hydroxymethylglutaryl-CoA R

2012
Platelets in vascular disease.
    Clinical hemorheology and microcirculation, 2013, Volume: 53, Issue:1-2

    Topics: Aspirin; Atherosclerosis; Blood Platelets; Clopidogrel; Hemostasis; Humans; Plaque, Atherosclerotic;

2013
Effect of S-aspirin, a novel hydrogen-sulfide-releasing aspirin (ACS14), on atherosclerosis in apoE-deficient mice.
    European journal of pharmacology, 2012, Dec-15, Volume: 697, Issue:1-3

    Topics: Animals; Apolipoproteins E; Aspirin; Atherosclerosis; Brachiocephalic Trunk; Cell Line; Chemotaxis;

2012