Page last updated: 2024-10-22

aspirin and Ataxia Telangiectasia

aspirin has been researched along with Ataxia Telangiectasia in 2 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Aguado, J1
Chaggar, HK1
Gómez-Inclán, C1
Shaker, MR1
Leeson, HC1
Mackay-Sim, A1
Wolvetang, EJ1
Shackelford, RE1
Manuszak, RP1
Johnson, CD1
Hellrung, DJ1
Steele, TA1
Link, CJ1
Wang, S1

Other Studies

2 other studies available for aspirin and Ataxia Telangiectasia

ArticleYear
Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids.
    Aging cell, 2021, Volume: 20, Issue:9

    Topics: Aspirin; Astrocytes; Ataxia Telangiectasia; Brain; Cells, Cultured; Cellular Senescence; Dose-Respon

2021
Desferrioxamine treatment increases the genomic stability of Ataxia-telangiectasia cells.
    DNA repair, 2003, Sep-18, Volume: 2, Issue:9

    Topics: Aspirin; Ataxia Telangiectasia; Cell Line; Chromosomal Instability; Colony-Forming Units Assay; Defe

2003