aspirin has been researched along with Asystole in 32 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Cardiac Arrhythmia Suppression Trial (CAST) was a multicenter double-blind, placebo-controlled study designed to determine whether suppression of ventricular ectopic activity by means of antiarrhythmic drugs (encainide, flecainide or moricizine) after acute myocardial infarction would reduce the incidence of arrhythmic death." | 9.07 | Circadian pattern of arrhythmic death in patients receiving encainide, flecainide or moricizine in the Cardiac Arrhythmia Suppression Trial (CAST). ( Barker, AH; Brooks, MM; Capone, R; Echt, DS; Greene, HL; Liebson, PR; Mitchell, LB; Peters, RW, 1994) |
| "Comatose survivors of out of hospital cardiac arrest were included and divided into two groups, depending on whether dual platelet inhibition with peroral ticagrelor and aspirin was given or not." | 7.80 | Platelet aggregation and clot formation in comatose survivors of cardiac arrest treated with induced hypothermia and dual platelet inhibition with aspirin and ticagrelor; a prospective observational study. ( Dankiewicz, J; Friberg, H; Kander, T; Schött, U, 2014) |
| "The Cardiac Arrhythmia Suppression Trial (CAST) was a multicenter double-blind, placebo-controlled study designed to determine whether suppression of ventricular ectopic activity by means of antiarrhythmic drugs (encainide, flecainide or moricizine) after acute myocardial infarction would reduce the incidence of arrhythmic death." | 5.07 | Circadian pattern of arrhythmic death in patients receiving encainide, flecainide or moricizine in the Cardiac Arrhythmia Suppression Trial (CAST). ( Barker, AH; Brooks, MM; Capone, R; Echt, DS; Greene, HL; Liebson, PR; Mitchell, LB; Peters, RW, 1994) |
| " Samter's triad consists of nasal polyps, asthma, and aspirin (or nonsteroidal anti-inflammatory drug) sensitivity." | 3.83 | A Case of Kounis Type I in a Young Woman With Samter's Triad. ( Chou, A; Rayner-Hartley, E; Saw, J; Sedlak, T, 2016) |
| " We present the case of a 50-year-old male with the Samter-Beer triad of asthma, nasal polyps, and salicylate intolerance with an ST elevation myocardial infarction complicated with cardiac arrest due to multi-vessel coronary artery spasm secondary to aspirin anaphylaxis." | 3.81 | Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline. ( Ihdayhid, AR; Rankin, J, 2015) |
| "Comatose survivors of out of hospital cardiac arrest were included and divided into two groups, depending on whether dual platelet inhibition with peroral ticagrelor and aspirin was given or not." | 3.80 | Platelet aggregation and clot formation in comatose survivors of cardiac arrest treated with induced hypothermia and dual platelet inhibition with aspirin and ticagrelor; a prospective observational study. ( Dankiewicz, J; Friberg, H; Kander, T; Schött, U, 2014) |
| "Infectious mononucleosis is a common viral illness of adolescence." | 2.48 | Spontaneous splenic rupture in infectious mononucleosis: case report and review of the literature. ( Pomerantz, WJ; Rinderknecht, AS, 2012) |
| "Up to 90% of cardiac arrests are due to acute myocardial infarction or severe myocardial ischaemia." | 1.35 | Out-of-hospital thrombolysis during cardiopulmonary resuscitation in patients with high likelihood of ST-elevation myocardial infarction. ( Arntz, HR; Breckwoldt, J; Dissmann, R; Marschalk, A; Müller, D; Wenzel, V, 2008) |
| " After controlling for age, prehospital dosage of epinephrine, and the duration of cardiac arrest we found a non significant trend towards good neurological recovery when thrombolytic therapy was given (OR 1." | 1.31 | Thrombolytic therapy after cardiac arrest and its effect on neurological outcome. ( Gabriel, D; Holzer, M; Kuerkciyan, I; Laggner, AN; Muellner, M; Schreiber, W; Sterz, F, 2002) |
| "Concomitant drug therapies after sudden cardiac arrest and their potential effect of altering heart rate variability (HRV) represent confounding factors in interpreting the outcome of nonpharmacologic therapies on HRV." | 1.29 | Description of time- and frequency- domain-based measures of heart rate variability in individuals taking antiarrhythmics, beta blockers, calcium channel blockers, and/or antihypertensive drugs after sudden cardiac arrest. ( Burr, RL; Cain, KC; Cowan, MJ; Narayanan, SB; Pike, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Siegel, AJ | 2 |
| Liu, H | 1 |
| Li, J | 1 |
| Chen, M | 1 |
| Yang, T | 1 |
| Ruan, Z | 1 |
| Su, J | 1 |
| Xing, Y | 1 |
| Varol, S | 1 |
| Şahin, İ | 1 |
| Kum, G | 1 |
| Katkat, F | 1 |
| Okuyan, E | 1 |
| Buitrago, I | 2 |
| Wolinsky, D | 2 |
| Asher, CR | 1 |
| Alraies, MC | 1 |
| Asher, C | 1 |
| Kander, T | 1 |
| Dankiewicz, J | 1 |
| Friberg, H | 1 |
| Schött, U | 1 |
| Ihdayhid, AR | 1 |
| Rankin, J | 1 |
| Singletary, EM | 1 |
| Zideman, DA | 1 |
| De Buck, ED | 1 |
| Chang, WT | 1 |
| Jensen, JL | 1 |
| Swain, JM | 1 |
| Woodin, JA | 1 |
| Blanchard, IE | 1 |
| Herrington, RA | 1 |
| Pellegrino, JL | 1 |
| Hood, NA | 1 |
| Lojero-Wheatley, LF | 1 |
| Markenson, DS | 1 |
| Yang, HJ | 1 |
| Rayner-Hartley, E | 1 |
| Chou, A | 1 |
| Saw, J | 1 |
| Sedlak, T | 1 |
| Horn, P | 1 |
| Pasch, A | 1 |
| Maxhera, B | 1 |
| Kelm, M | 1 |
| Westenfeld, R | 1 |
| Yanagawa, Y | 1 |
| Omori, K | 1 |
| Takeuchi, I | 1 |
| Jitsuiki, K | 1 |
| Yoshizawa, T | 1 |
| Ishikawa, K | 1 |
| Kando, Y | 1 |
| Fukata, M | 1 |
| Ohsaka, H | 1 |
| García Paredes, T | 1 |
| Escudero Varela, JC | 1 |
| Mora Ordóñez, JM | 1 |
| Avlonitis, VS | 1 |
| Planas, S | 1 |
| Hayes, AM | 1 |
| Parry, A | 1 |
| Rinderknecht, AS | 1 |
| Pomerantz, WJ | 1 |
| Seniuk, W | 1 |
| Mularek-Kubzdela, T | 1 |
| Grygier, M | 1 |
| Grajek, S | 1 |
| Cieśliński, A | 1 |
| SoRelle, R | 1 |
| BEVERIDGE, GW | 1 |
| FORSHALL, W | 1 |
| MUNRO, JF | 1 |
| OWEN, JA | 1 |
| WESTON, IA | 1 |
| Hwong, TM | 1 |
| Arifi, AA | 1 |
| Wan, IY | 1 |
| Thung, KH | 1 |
| Wan, S | 1 |
| Sung, RY | 1 |
| Yim, AP | 1 |
| Arntz, HR | 1 |
| Wenzel, V | 1 |
| Dissmann, R | 1 |
| Marschalk, A | 1 |
| Breckwoldt, J | 1 |
| Müller, D | 1 |
| Leffert, RL | 1 |
| Hackett, RL | 1 |
| Gross, F | 1 |
| Cowan, MJ | 1 |
| Pike, K | 1 |
| Burr, RL | 1 |
| Cain, KC | 1 |
| Narayanan, SB | 1 |
| Peters, RW | 1 |
| Mitchell, LB | 1 |
| Brooks, MM | 1 |
| Echt, DS | 1 |
| Barker, AH | 1 |
| Capone, R | 1 |
| Liebson, PR | 1 |
| Greene, HL | 1 |
| Matsuno, N | 1 |
| Muto, S | 1 |
| Uchiyama, M | 1 |
| Kozaki, K | 1 |
| Kageyama, T | 1 |
| Suzuki, T | 1 |
| Kozaki, M | 1 |
| Nagao, T | 1 |
| Schreiber, W | 1 |
| Gabriel, D | 1 |
| Sterz, F | 1 |
| Muellner, M | 1 |
| Kuerkciyan, I | 1 |
| Holzer, M | 1 |
| Laggner, AN | 1 |
| Ryan, WA | 1 |
| Roden, VJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Safety Study in Patients Included in the CLARINET Study With Cyanotic Congenital Heart Disease Palliated With a Systemic-to-pulmonary Artery Shunt and for Whom the Shunt is Still in Place at One Year of Age[NCT00833703] | Phase 3 | 49 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [NCT00000526] | Phase 3 | 0 participants | Interventional | 1986-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
For all reported bleeding events, the type and the etiology of the bleeding event were collected. Participants who experienced bleeding events during the 'on-treatment period' were counted by bleeding type and etiology. (NCT00833703)
Timeframe: Up to a maximum of 6 months
| Intervention | participants (Number) | |
|---|---|---|
| Spontaneous | Puncture (vascular access site) | |
| Clopidogrel 0.2 mg/kg/Day | 1 | 1 |
| Placebo | 0 | 0 |
"All bleeding events experienced during the study period were collected as for any Adverse Event.~The 'on-treatment' period was defined as the period from inclusion in the extension study up to 28 days after treatment discontinuation, and participants who experienced bleeding events during that period were counted." (NCT00833703)
Timeframe: Up to a maximum of 6 months
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| Any bleeding event | - Serious | - Serious with an outcome of death | - Leading to permanent treatment discontinuation | |
| Clopidogrel 0.2 mg/kg/Day | 2 | 0 | 0 | 0 |
| Placebo | 0 | 0 | 0 | 0 |
"Outcome events, shunt thrombosis requiring intervention or death, experienced during the study period were recorded.~Participants were counted excluding the events that occured after the participant's protocol study end (occurrence of shunt thrombosis, next surgical procedure for correction of the congenital heart disease, death, or 18 months of age, whichever came first)." (NCT00833703)
Timeframe: Up to a maximum of 6 months
| Intervention | participants (Number) | |
|---|---|---|
| shunt thrombosis requiring intervention | death | |
| Clopidogrel 0.2 mg/kg/Day | 0 | 0 |
| Placebo | 0 | 1 |
3 reviews available for aspirin and Asystole
| Article | Year |
|---|---|
A Meta-Analysis of Randomized and Observational Studies: Aspirin Protects from Cardiac Surgery-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Aspirin; Cause of Death; Coma; Coronary Artery Bypass; Heart Arrest; Heart Bloc | 2019 |
Part 9: First Aid: 2015 International Consensus on First Aid Science With Treatment Recommendations.
Topics: Airway Management; Aspirin; Asthma; Cardiopulmonary Resuscitation; Chest Pain; Emergencies; Emergenc | 2015 |
Spontaneous splenic rupture in infectious mononucleosis: case report and review of the literature.
Topics: Abdominal Pain; Adolescent; Air Ambulances; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2012 |
1 trial available for aspirin and Asystole
| Article | Year |
|---|---|
Circadian pattern of arrhythmic death in patients receiving encainide, flecainide or moricizine in the Cardiac Arrhythmia Suppression Trial (CAST).
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Circadian Rhythm; Death, Sudden, Cardia | 1994 |
28 other studies available for aspirin and Asystole
| Article | Year |
|---|---|
Pre-Race Aspirin to Enhance Primary Prevention of Marathon-Related Cardiac Arrest: Confronting Pheidippides' Legacy.
Topics: Aspirin; Death, Sudden, Cardiac; Heart Arrest; Humans; Marathon Running; Primary Prevention | 2023 |
Coronary stent embolism to the right posterior cerebral artery.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Atropine; Clopidogrel; Coronary Angiography; Coronary Arter | 2020 |
Aspirin Use to Reduce the Risk of Sports-Related Cardiac Arrest in High-Risk Athletes.
Topics: Aspirin; Athletes; Heart; Heart Arrest; Humans; Sports | 2019 |
Syncope during a pharmacologic nuclear stress test.
Topics: Adenosine; Aspirin; Aspirin, Dipyridamole Drug Combination; Dipyridamole; Drug Combinations; Drug In | 2014 |
A serious complication of a common stress test (May 2014).
Topics: Adenosine; Aspirin; Dipyridamole; Female; Heart Arrest; Humans; Platelet Aggregation Inhibitors; Rad | 2014 |
In reply.
Topics: Adenosine; Aspirin; Dipyridamole; Female; Heart Arrest; Humans; Platelet Aggregation Inhibitors; Rad | 2014 |
Platelet aggregation and clot formation in comatose survivors of cardiac arrest treated with induced hypothermia and dual platelet inhibition with aspirin and ticagrelor; a prospective observational study.
Topics: Adenosine; Adult; Aged; Aspirin; Blood Platelets; Coma; Combined Modality Therapy; Drug Therapy, Com | 2014 |
Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline.
Topics: Anaphylaxis; Aspirin; Asthma; Chest Pain; Coronary Stenosis; Coronary Vessels; Electrocardiography; | 2015 |
A Case of Kounis Type I in a Young Woman With Samter's Triad.
Topics: Acute Coronary Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; | 2016 |
When extracorporeal CPR fails-fatal ionized hypocalcemia during cardiac arrest.
Topics: Adult; Aspirin; Drug Overdose; Extracorporeal Membrane Oxygenation; Fatal Outcome; Female; Heart Arr | 2016 |
Cardiac arrest at high elevation with a favorable outcome.
Topics: Adult; Air Ambulances; Altitude; Aspirin; Computed Tomography Angiography; Coronary Angiography; Cor | 2017 |
How do aspirin and nitroglycerin differ in heart attack prevention and treatment?
Topics: Aspirin; Heart Arrest; Humans; Nitroglycerin; Vasodilator Agents | 2009 |
[Non-occlusive stent thrombosis associated to cardiocirculatory arrest].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosi | 2010 |
Occlusion of modified Blalock-Taussig shunt after clopidogrel cessation.
Topics: Anticoagulants; Aspirin; Blalock-Taussig Procedure; Clopidogrel; Fatal Outcome; Graft Occlusion, Vas | 2012 |
Cardiac arrest related to coronary spasm in patients with variant angina: a three-case study.
Topics: Amiodarone; Angina Pectoris, Variant; Anti-Arrhythmia Agents; Aspirin; Calcium Channel Blockers; Car | 2002 |
Percutaneous intervention a winner--even in patients with stable, single-vessel disease.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Congresses as Topic; Contraindications; Coronary Artery Dis | 2003 |
ACUTE SALICYLATE POISONING IN ADULTS.
Topics: Acute Kidney Injury; Aspirin; Blood Chemical Analysis; Bronchopneumonia; Coma; Diagnosis, Differenti | 1964 |
Rupture of a giant coronary artery aneurysm due to Kawasaki disease.
Topics: Anticoagulants; Aspirin; Cardiac Tamponade; Child, Preschool; Combined Modality Therapy; Coronary An | 2004 |
Out-of-hospital thrombolysis during cardiopulmonary resuscitation in patients with high likelihood of ST-elevation myocardial infarction.
Topics: Aspirin; Cardiopulmonary Resuscitation; Drug Therapy, Combination; Emergency Medical Services; Femal | 2008 |
Aspergillus aortitis following replacement of aortic valve.
Topics: Adult; Aortic Diseases; Aspergillus; Aspirin; Cardiac Catheterization; Cephalothin; Extracorporeal C | 1967 |
[Infarction prophylaxis--prevention of the sudden heart death? An alternative].
Topics: Adrenergic beta-Antagonists; Anticoagulants; Aspirin; Dipyridamole; Female; Heart Arrest; Humans; Ma | 1982 |
Description of time- and frequency- domain-based measures of heart rate variability in individuals taking antiarrhythmics, beta blockers, calcium channel blockers, and/or antihypertensive drugs after sudden cardiac arrest.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Calcium Chann | 1993 |
Beneficial effect of aspirin and protease inhibitor as graft conditioning using machine perfusion in warm ischemically injured kidneys.
Topics: Animals; Aspirin; Creatinine; Dogs; Graft Survival; Heart Arrest; Humans; Kidney; Kidney Transplanta | 1997 |
Thrombolytic therapy after cardiac arrest and its effect on neurological outcome.
Topics: Aged; Aspirin; Cardiopulmonary Resuscitation; Case-Control Studies; Cerebrovascular Circulation; Con | 2002 |
Overview of American Heart Association protocols. Part 2--A.C.L.S.
Topics: Adult; Advanced Cardiac Life Support; Algorithms; American Heart Association; Analgesics, Opioid; An | 2000 |
Medical controversy: does an aspirin a day keep heart attacks away?
Topics: Adult; Aspirin; Heart Arrest; Humans; Male | 1988 |
Aspirin: a dangerous pulmonary foreign body.
Topics: Aspirin; Child, Preschool; Female; Foreign Bodies; Heart Arrest; Humans; Infant; Inhalation; Male; R | 1973 |
Polycythemia vera complicated by acute leukemia and a rapidly enlarging mass in the left upper abdominal quadrant.
Topics: Aspirin; Female; Heart Arrest; Humans; Leukemia, Myeloid; Metaraminol; Middle Aged; Polycythemia Ver | 1967 |