aspirin has been researched along with Astrocytoma, Grade IV in 7 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goal in this study was to investigate the antitumor effect of aspirin in glioblastoma cells and the molecular mechanism involved in its antineoplastic activities." | 7.77 | Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor-mediated transcriptional activity. ( Han, L; Huang, K; Jiang, T; Kang, C; Lan, F; Pu, P; Shi, Z; Yang, Y; Yuan, X; Yue, X; Zhang, J; Zou, J, 2011) |
| "The in vitro antiproliferative and apoptosis inducing properties of the nonsteroidal anti-inflammatory drugs (NSAIDs) like acetyl salicylic acid (aspirin) and indomethacin were investigated in T98G human glioblastoma cells to explore their potential role in the chemoprevention of human glioma." | 7.72 | Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells. ( Amin, R; Eling, TE; Ishibashi, M; Islam, A; Kamitani, H; Sho, A; Sultana, H; Taniura, S; Watanabe, T, 2003) |
| " Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture." | 7.70 | Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000) |
| "Aspirin has been reported to induce apoptosis in various cancer cell lines." | 5.35 | Aspirin induces apoptosis through the blockade of IL-6-STAT3 signaling pathway in human glioblastoma A172 cells. ( Bae, MK; Bae, SK; Kim, JY; Kim, SR; Wee, HJ; Yoo, MA, 2009) |
| "The goal in this study was to investigate the antitumor effect of aspirin in glioblastoma cells and the molecular mechanism involved in its antineoplastic activities." | 3.77 | Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor-mediated transcriptional activity. ( Han, L; Huang, K; Jiang, T; Kang, C; Lan, F; Pu, P; Shi, Z; Yang, Y; Yuan, X; Yue, X; Zhang, J; Zou, J, 2011) |
| "The in vitro antiproliferative and apoptosis inducing properties of the nonsteroidal anti-inflammatory drugs (NSAIDs) like acetyl salicylic acid (aspirin) and indomethacin were investigated in T98G human glioblastoma cells to explore their potential role in the chemoprevention of human glioma." | 3.72 | Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells. ( Amin, R; Eling, TE; Ishibashi, M; Islam, A; Kamitani, H; Sho, A; Sultana, H; Taniura, S; Watanabe, T, 2003) |
| " Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture." | 3.70 | Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000) |
| "Aspirin has been reported to induce apoptosis in various cancer cell lines." | 1.35 | Aspirin induces apoptosis through the blockade of IL-6-STAT3 signaling pathway in human glioblastoma A172 cells. ( Bae, MK; Bae, SK; Kim, JY; Kim, SR; Wee, HJ; Yoo, MA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Marx, S | 1 |
| Altmann, R | 1 |
| Baschin, M | 1 |
| Paland, H | 1 |
| Rauch, B | 1 |
| Kohlmann, T | 1 |
| Schroeder, HWS | 1 |
| Navone, SE | 1 |
| Guarnaccia, L | 1 |
| Cordiglieri, C | 1 |
| Crisà, FM | 1 |
| Caroli, M | 1 |
| Locatelli, M | 1 |
| Schisano, L | 1 |
| Rampini, P | 1 |
| Miozzo, M | 1 |
| La Verde, N | 1 |
| Riboni, L | 1 |
| Campanella, R | 1 |
| Marfia, G | 1 |
| Guenzle, J | 1 |
| Garrelfs, NWC | 1 |
| Goeldner, JM | 1 |
| Weyerbrock, A | 1 |
| Kim, SR | 1 |
| Bae, MK | 1 |
| Kim, JY | 1 |
| Wee, HJ | 1 |
| Yoo, MA | 1 |
| Bae, SK | 1 |
| Lan, F | 1 |
| Yue, X | 1 |
| Han, L | 1 |
| Yuan, X | 1 |
| Shi, Z | 1 |
| Huang, K | 1 |
| Yang, Y | 1 |
| Zou, J | 1 |
| Zhang, J | 1 |
| Jiang, T | 1 |
| Pu, P | 1 |
| Kang, C | 1 |
| Amin, R | 1 |
| Kamitani, H | 1 |
| Sultana, H | 1 |
| Taniura, S | 1 |
| Islam, A | 1 |
| Sho, A | 1 |
| Ishibashi, M | 1 |
| Eling, TE | 1 |
| Watanabe, T | 1 |
| Casper, D | 1 |
| Lekhraj, R | 1 |
| Yaparpalvi, US | 1 |
| Pidel, A | 1 |
| Jaggernauth, WA | 1 |
| Werner, P | 1 |
| Tribius, S | 1 |
| Rowe, JD | 1 |
| LaSala, PA | 1 |
7 other studies available for aspirin and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Preoperative Thrombocytosis is Not Associated with Overall Survival in 309 Glioblastoma Patients.
Topics: Aspirin; Brain Neoplasms; Fibrinogen; Glioblastoma; Humans; Prognosis; Retrospective Studies; Thromb | 2022 |
Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplas | 2018 |
Cyclooxygenase (COX) Inhibition by Acetyl Salicylic Acid (ASA) Enhances Antitumor Effects of Nitric Oxide in Glioblastoma In Vitro.
Topics: Antineoplastic Agents; Aspirin; Azo Compounds; Cell Line, Tumor; Cell Survival; Cyclooxygenase Inhib | 2019 |
Aspirin induces apoptosis through the blockade of IL-6-STAT3 signaling pathway in human glioblastoma A172 cells.
Topics: Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Glioblastoma; Humans; Interleukin-6; Ph | 2009 |
Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor-mediated transcriptional activity.
Topics: Aspirin; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Glioblastoma | 2011 |
Aspirin and indomethacin exhibit antiproliferative effects and induce apoptosis in T98G human glioblastoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Division; Cyclooxygenase 1; Cycloo | 2003 |
Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.
Topics: Acetaminophen; Adult; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Brain; Brain Neoplasms; Ce | 2000 |