aspirin has been researched along with Asthma, Bronchial in 1213 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Numerous open trials have demonstrated the beneficial clinical effects of aspirin desensitization (AD) in patients with aspirin-induced asthma (AIA)." | 9.19 | Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study. ( Bochenek, G; Ćmiel, A; Gielicz, A; Niżankowska-Mogilnicka, E; Plutecka, H; Sanak, M; Stręk, P; Świerczyńska-Krępa, M; Szczeklik, A, 2014) |
| "A special regulatory role for prostaglandin E2 has been postulated in aspirin-induced asthma." | 9.13 | Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity. ( Cmiel, A; Gawlewicz-Mroczka, A; Gielicz, A; Mastalerz, L; Sanak, M; Szczeklik, A, 2008) |
| "Aspirin can cause bronchoconstriction in some asthmatic patients through increased production of proinflammatory mediators, particularly leukotrienes." | 9.13 | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. ( Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A, 2008) |
| "Randomised data in men show a small but significant reduction in the risk of adult-onset asthma among those given aspirin." | 9.13 | Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study. ( Barr, RG; Buring, JE; Gaziano, JM; Kurth, T, 2008) |
| "Aspirin (ASA) and several other nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclo-oxygenase (COX) enzyme both isoforms 1 and 2, and can precipitate asthmatic attacks in aspirin-induced asthmatics." | 9.12 | Nasal and bronchial tolerability of Rofecoxib in patients with aspirin induced asthma. ( Dal Negro, R; Guerriero, M; Micheletto, C; Tognella, S, 2006) |
| "To study the safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, and to determine whether it cross-reacts with asthma in patients with aspirin-exacerbated respiratory disease (AERD)." | 9.12 | Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory disease. ( Ahmed, I; El Gaafary, M; El Miedany, Y; Youssef, S, 2006) |
| "The anti-inflammatory actions of acetylsalicylic acid (ASA)/non-steroidal anti-inflammatory drugs (NSAIDs) are thought to be due to inhibition of COX-2, whereas the side effects such as gastric damage and aspirin-induced asthma are mediated through inhibition of COX-1." | 9.12 | Safety of meloxicam in aspirin-hypersensitive patients with asthma and/or nasal polyps. A challenge-proven study. ( Bavbek, S; Dursun, AB; Dursun, E; Eryilmaz, A; Misirligil, Z, 2007) |
| "Nasal polyposis associated with aspirin-intolerant asthma tends to be difficult to control, with frequent recurrences." | 9.12 | Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma. ( Darby, Y; Ogata, N; Scadding, G, 2007) |
| "Aspirin-induced asthma (AIA) is a clinical syndrome characterized by acute airway reaction to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS)." | 9.11 | Montelukast 10 mg improves nasal function and nasal response to aspirin in ASA-sensitive asthmatics: a controlled study vs placebo. ( Dal Negro, RW; Micheletto, C; Pomari, C; Tognella, S; Trevisan, F; Visconti, M, 2004) |
| "Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can precipitate adverse reactions in two apparently different clinical conditions: bronchial asthma and chronic idiopathic urticaria (CIU)." | 9.11 | Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma. ( Mastalerz, L; Sanak, M; Setkowicz, M; Szczeklik, A, 2004) |
| "Aspirin-induced asthma (AIA) is associated with increased production of cysteinyl leukotrienes (CysLT)." | 9.11 | Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma. ( Haggart, K; Lee, DK; Lipworth, BJ; Robb, FM, 2004) |
| "The exact mechanism of aspirin-induced asthma is not clear." | 9.11 | Tacrolimus reduces urinary excretion of leukotriene E(4) and inhibits aspirin-induced asthma to threshold dose of aspirin. ( Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S, 2004) |
| "To determine whether celecoxib, a selective cyclooxygenase 2 (COX-2) inhibitor, cross-reacts in patients with aspirin-exacerbated respiratory disease (AERD) with asthma." | 9.10 | The safety of celecoxib in patients with aspirin-sensitive asthma. ( Simon, RA; Stevenson, DD; Woessner, KM, 2002) |
| "Patients with asthma who have aspirin sensitivity have greater cysteinyl leukotriene production and greater airway hyperresponsiveness to the effects of inhaled cysteinyl leukotrienes than their aspirin-tolerant counterparts." | 9.10 | Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis. ( Corrigan, CJ; Lee, TH; Parikh, A; Scadding, G; Sousa, AR, 2002) |
| " Changes in nasal and asthma symptoms, combined with changes in oral prednisone, were recorded daily during 4 weeks before and after desensitization." | 9.10 | Early effects of aspirin desensitization treatment in asthmatic patients with aspirin-exacerbated respiratory disease. ( Berges-Gimeno, MP; Simon, RA; Stevenson, DD, 2003) |
| "Subjects with aspirin-intolerant asthma (AIA) respond with bronchoconstriction and extrapulmonary adverse reactions to conventional nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit the cyclooxygenase (COX) step in the biosynthesis of prostaglandins." | 9.10 | Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. ( Bochenek, G; Dahlén, B; Dahlén, SE; Drupka, D; Gyllfors, P; Isakson, PC; Kumlin, M; Lefkowith, JB; Mejza, F; Murray, JJ; Nizankowska, E; Overholt, J; Sheller, J; Szczeklik, A, 2003) |
| "The aim of this study was to assess the efficacy of leucotrien- antagonists in aspirin-intolerant asthma (AIA)." | 9.10 | [The effectiveness of leukotriene antagonists in the treatment of aspirin-intolerant asthmatic patients]. ( Arvin-Berod, C; Paganin, F; Poubeau, P; Yvin, JL, 2003) |
| "Aspirin-induced asthma/rhinitis (AIAR) is characterized by the altered metabolism of leukotrienes and proinflammatory prostaglandins." | 9.10 | Nasal versus bronchial and nasal response to oral aspirin challenge: Clinical and biochemical differences between patients with aspirin-induced asthma/rhinitis. ( Gielicz, A; Nizankowska-Mogilnicka, E; Swierczynska, M; Szczeklik, A; Zarychta, J, 2003) |
| "We have aimed to determine the sensitivity and specificity of a simpler technique with less risk than oral provocation to diagnose aspirin-induced asthma (AIA)." | 9.10 | Nasal provocation test (NPT) with aspirin: a sensitive and safe method to diagnose aspirin-induced asthma (AIA). ( Alonso-Llamazares, A; Cimarra-Alvarez, M; Domínguez-Ortega, J; Martinez-Cócera, C; Mesa del Castillo, M; Robledo-Echarren, T, 2002) |
| "Little is known about the anti-asthmatic effects of powerful anti-inflammatory agents such as aspirin-like drugs." | 9.09 | Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1999) |
| "The underlying mechanisms of bronchoconstriction in aspirin-intolerant asthmatics (AIAs) are still unknown, but the hypothesis of an altered metabolism of arachidonic acid is generally accepted." | 9.09 | Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics. ( Baenkler, HW; Göde, UC; Schäfer, D; Schmid, M, 1999) |
| "This study was designed to investigate the protective effect of roxithromycin on airway responsiveness to the sulpyrine provocation test and to investigate whether this protective activity is associated with a reduction in aspirin-induced excretion of urinary leucotriene E4 (u-LTE4), a marker of cysteinyl leucotriene overproduction that participates in the pathogenesis of aspirin-intolerant asthma." | 9.09 | Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Nakagawa, H; Sakamoto, H; Shoji, T; Yoshida, S, 1999) |
| "Prostaglandins of the E series and misoprostol (a stable analogue of prostaglandin E(1)) prevent bronchoconstriction following aspirin ingestion or inhalation in subjects with aspirin sensitive asthma." | 9.09 | A six week double blind, placebo controlled, crossover study of the effect of misoprostol in the treatment of aspirin sensitive asthma. ( Szmidt, M; Wasiak, W, 1999) |
| "Bradykinin (BK) is a mediator of inflammation in asthma with potent bronchoconstrictor actions." | 9.09 | Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma. ( Barnes, PJ; Chung, KF; Kharitonov, SA; Sapienza, MM, 1999) |
| "Albeit its exact pathogenesis is still ambiguous; aspirin-intolerant asthma is one of several types of asthma for which antileukotriene therapy is useful, because it is widely accepted that bronchial over-production of leukotrienes may be involved in its pathogenesis." | 9.09 | Efficacy of leukotriene receptor antagonist in bronchial hyperresponsiveness and hypersensitivity to analgesic in aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Ishizaki, Y; Nakabayashi, M; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Yoshida, S, 2000) |
| "In 35 asthmatic patients with acetylsalicylic acid (aspirin; ASA) intolerance (AIA) and 15 asthmatics tolerating ASA well, the authors compared the diagnostic value of the placebo-controlled oral ASA versus inhaled L-lysine (L) ASA challenges." | 9.09 | Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma. ( Bestyńska-Krypel, A; Cmiel, A; Nizankowska, E; Szczeklik, A, 2000) |
| "In a subset of patients with asthma, aspirin and several other non-steroidal anti-inflammatory drugs (NSAID) that inhibit simultaneously cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) precipitate dangerous asthmatic attacks." | 9.09 | Safety of a specific COX-2 inhibitor in aspirin-induced asthma. ( Bochenek, G; Mejza, F; Nagraba, K; Nizankowska, E; Swierczynska, M; Szczeklik, A, 2001) |
| "The goal of this study was to determine whether rofecoxib cross-reacts in aspirin-sensitive patients with asthma." | 9.09 | Lack of cross-reactivity between rofecoxib and aspirin in aspirin-sensitive patients with asthma. ( Simon, RA; Stevenson, DD, 2001) |
| "Although administration of cromolyn sodium is one of the most useful drugs for the treatment of aspirin-intolerant asthma (AIA), both its pharmacologic mechanism of action and association with the pathogenesis remain obscure." | 9.09 | Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Ishizaki, Y; Nakabayashi, M; Nakagawa, H; Shoji, T; Yoshida, S, 2001) |
| "Nine patients with moderate and severe aspirin bronchial asthma (ABA) received epifamine (a course dose 400 mg) in addition to continuous antiasthmatic therapy." | 9.09 | [Epifamine efficacy in aspirin bronchial asthma]. ( Bondarenko, VL; Evsiukova, EV; Khavinson, VKh; Sinitsina, TM; Totoliam, AA; Trofimov, VI, 2001) |
| "Cross-sensitivity between aspirin and acetaminophen in aspirin-sensitive asthmatic patients has been reported with frequencies ranging from 0% to 29%." | 9.08 | Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects. ( Christiansen, SC; Mathison, DA; Schrank, PJ; Settipane, RA; Simon, RA; Stevenson, DD, 1995) |
| "We conclude that aspirin-sensitive patients with asthma are not preferentially sensitive to hydrocortisone and that hydrocortisone sodium succinate does not cross-react or cross-desensitize with aspirin." | 9.08 | Hydrocortisone sodium succinate does not cross-react with aspirin in aspirin-sensitive patients with asthma. ( Feigenbaum, BA; Simon, RA; Stevenson, DD, 1995) |
| "Intravenous (n = 21) and inhalational maintenance anaesthesia (n = 21) were compared by random allocation in patients with the aspirin intolerance syndrome undergoing endoscopic nasal procedures." | 9.08 | A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome. ( Novak-Jankovic, V; Paver-Erzen, V; Podboj, J, 1995) |
| "Inhaled lysine acetylsalicylate and furosemide exert a mutually potentiating protective activity on experimentally induced bronchoconstriction in asthma." | 9.08 | Steroid-sparing effect of inhaled lysine acetylsalicylate and furosemide in high-dose beclomethasone-dependent asthma. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1995) |
| "We performed a double-blind, two-phase study on protective and bronchodilator effects of prostaglandins E2 and E1 (PGE2, PGE1) and salbutamol in patients with aspirin-induced asthma (AIA)." | 9.08 | Protective and bronchodilator effects of prostaglandin E and salbutamol in aspirin-induced asthma. ( Cmiel, A; Mastalerz, L; Nizankowska, E; Szczeklik, A, 1996) |
| "Bronchial overproduction of leukotrienes and inhibition of prostaglandin synthesis are involved in the pathogenesis of aspirin-induced asthma." | 9.08 | Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma. ( Armetti, L; Bianco, S; Folco, GC; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sala, A; Sestini, P; Vaghi, A, 1996) |
| " Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 9.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
| "When administered by inhalation, histamine provokes dose-related bronchoconstriction in asthmatic subjects mainly by a direct activation of histamine H1-receptors on airway smooth muscle." | 9.08 | Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Paolino, G; Polosa, R; Prosperini, G, 1996) |
| "When administered by inhalation, bradykinin provokes dose-related bronchoconstriction in asthmatic subjects by a mechanism believed to involve activation of sensory nerve endings." | 9.08 | Activity of inhaled lysine acetylsalicylate (L-ASA) on bradykinin-induced bronchoconstriction in asthmatics: evidence of contribution of prostaglandins. ( Crimi, N; Magrì, S; Milazzo, VL; Pagano, C; Paolino, G; Polosa, R; Prosperini, G; Santonocito, G, 1997) |
| "We performed a double-blind, crossover, placebo-controlled study on the effect of fluticasone propionate (FP) treatment on chronic eosinophilic rhinosinusitis in 15 patients with aspirin-induced asthma (AIA)." | 9.08 | Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma. ( Duplaga, M; Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1997) |
| "Inhalation of cromolyn sodium protects against sulpyrine-induced bronchoconstriction and prevents urinary leukotriene E4 (u-LTE4) excretion in aspirin-induced asthma." | 9.08 | Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthma. ( Amayasu, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Tajima, T; Yoshida, S, 1998) |
| "From bronchoprovocation studies and investigations of the acute effects of drugs that inhibit leukotrienes (LT), the hypothesis has emerged that leukotrienes are important mediators of airway obstruction and other symptoms in aspirin-intolerant asthma (AIA)." | 9.08 | Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. ( Bochenek, G; Boodhoo, TI; Dahlén, B; Dahlén, SE; Dubé, LM; Kumlin, M; Mastalerz, L; Nizankowska, E; Pinis, G; Swanson, LJ; Szczeklik, A; Wright, S; Zetterström, O, 1998) |
| "We determined the effect of a long acting beta2-agonist, salmeterol, on aspirin-induced asthma (AIA) attacks and urinary release of eicosanoids in a double-blind, placebo-controlled, crossover study in 10 asthmatics sensitive to aspirin." | 9.08 | Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism. ( Cmiel, A; Dworski, R; Mastalerz, L; Nizankowska, E; Oates, JA; Prokop, A; Sheller, JR; Szczeklik, A, 1998) |
| "This study was designed to investigate the protective effect of cromolyn sodium on airway sensitivity to sulpyrine, and bronchial responsiveness to methacholine, and to investigate whether this protective activity is associated with reduction in aspirin-induced excretion of urinary leukotriene E4 (u-LTE4), a marker of the cysteinyl LT overproduction that participates in the pathogenesis of aspirin-induced asthma." | 9.08 | Bronchial hyperresponsiveness, hypersensitivity to analgesics and urinary leukotriene E4 excretion in patients with aspirin-intolerant asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Nakabayashi, M; Nakagawa, H; Sakamoto, H; Sakamoto, M; Shoji, T; Tajimab, T; Yamawaki, Y; Yoshida, S, 1998) |
| "This study was designed to investigate the protective effect of acyclovir on airway responsiveness to the sulpyrine provocation test and to investigate whether this protective activity is associated with a reduction in aspirin-induced excretion of urinary leukotriene E4 (u-LTE4 ), a marker of cysteinyl leukotriene (LT) overproduction that participates in the pathogenesis of aspirin-induced asthma." | 9.08 | Effect of acyclovir on bronchoconstriction and urinary leukotriene E4 excretion in aspirin-induced asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Yamawaki, Y; Yoshida, S, 1998) |
| "The increase in nasal symptoms in aspirin-sensitive patients with asthma after aspirin ingestion is associated with increases in nasal tryptase, histamine, and cysteinyl leukotriene levels." | 9.07 | Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Igarashi, Y; Kaliner, MA; Lilly, CM; Rosenberg, MA; Rubin, P; White, MV, 1994) |
| " In aspirin-sensitive patients, acetylsalicylic acid causes an asthmatic reaction which typically lasts for 2 h or more after exposure." | 9.07 | Time-limited protective effect of inhaled frusemide against aspirin-induced bronchoconstriction in aspirin-sensitive asthmatics. ( Bianco, S; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Spagnotto, S; Vaghi, A, 1994) |
| "Oral challenge with aspirin or potential cross-reacting substances (including other nonsteroidal anti-inflammatory drugs [NSAIDs] or food and drug additives) is an effective method for establishing the presence of sensitivity to these substances in asthmatic subjects." | 9.07 | Oral challenges to detect aspirin and sulfite sensitivity in asthma. ( Simon, RA, 1994) |
| "The cysteinyl leukotrienes may play a central part in the mechanisms of aspirin-sensitive asthma." | 9.07 | Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. ( Arm, JP; Bell, GS; Foster, S; Lee, TH; MacMillan, R; Nasser, SM; Spruce, KE; Williams, AJ, 1994) |
| " To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients." | 9.07 | Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993) |
| "We have recently shown that oral aspirin provocation leads to an increase in LTE4 and a reduction in 11-dehydro-TXB2 levels in urine of patients with aspirin induced-asthma (AIA)." | 9.07 | Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge. ( Dworski, R; Nizankowska, E; Oates, JA; Sheller, JR; Sladek, K; Soja, J; Szczeklik, A, 1994) |
| "Recently, we have reported that a nebulized solution of sodium cromoglycate (SCG) (Intal), a well known antiallergic agent, has an acute bronchodilator effect in patients with aspirin-induced asthma (AIA)." | 9.07 | [Amlexanox has an acute bronchodilator effect in patients with aspirin-induced asthma (AIA)]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Satou, A; Taniguchi, M; Toyoshima, M, 1993) |
| "A subset of persons with asthma develop bronchospasm, naso-ocular, gastrointestinal, and/or dermal reactions after ingesting aspirin (ASA) or agents with the capacity to inhibit cyclooxygenase." | 9.07 | The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Israel, E; Lilly, CM; Rosenberg, MA; Rubin, P; Shapiro, J, 1993) |
| "The findings indicate that ongoing leukotriene production may be one cause of persistent airway obstruction in aspirin sensitive asthmatic subjects and that they may benefit from treatment with a leukotriene receptor antagonist." | 9.07 | Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. ( Dahlén, B; Dahlén, SE; Margolskee, DJ; Zetterström, O, 1993) |
| "Although the mechanism of aspirin-induced asthma and rhinitis is unknown, it has been suggested that adverse nasal and bronchial reactions are caused by an increased production of lipoxygenase products." | 9.07 | Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients. ( Bulbena, O; Gelpí, E; Montserrat, JM; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J, 1992) |
| "The FEV1 and urinary leukotriene E4 (LTE4) concentrations were determined in six aspirin-sensitive and six non-aspirin-sensitive asthmatic subjects before and after inhalation challenge with lysine-aspirin or placebo solution." | 9.07 | Urinary leukotriene E4 after lysine-aspirin inhalation in asthmatic subjects. ( Black, C; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Markendorf, A; Schmitz-Schumann, M; Tagari, P, 1992) |
| " However, we have found that some patients with aspirin-intolerant asthma (AIA) show significant improvement soon after a single inhalation of SCG nebulized solution." | 9.07 | [Sodium cromoglycate nebulized solution has an acute bronchodilative effect in patients with aspirin-intolerant asthma (AIA)]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1992) |
| " The goal of the present study was to determine if the inhalation of furosemide would inhibit the bronchoconstriction resulting from the inhalation of lysine-aspirin in aspirin-sensitive asthmatics." | 9.07 | Effect of inhaled furosemide on the bronchial response to lysine-aspirin inhalation in asthmatic subjects. ( Croce, M; Cukier, A; Light, RW; Teixeira, LR; Terra-Filho, M; Vargas, FS, 1992) |
| "Urinary leukotriene E4 (LTE4) concentrations have been measured in six asthmatic patients with aspirin sensitivity and in five asthmatic subjects tolerant of aspirin, before and after provocation with aspirin or placebo." | 9.07 | Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. ( Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P, 1991) |
| "We have determined the effect of prior inhalation of the LTD4 antagonist SK&F 104353 on the response to aspirin ingestion in six aspirin-sensitive asthmatic subjects (five women and one man 31 to 54 yr of age) in a randomized, double-blind, cross-over, placebo-controlled study." | 9.07 | The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma. ( Christie, PE; Lee, TH; Smith, CM, 1991) |
| "Treatment of inflammatory diseases of asthmatics can be a serious problem since some patients show intolerance to aspirin and other non-steroidal, anti-inflammatory drugs that are cyclooxygenase inhibitors." | 9.06 | Choline magnesium trisalicylate in patients with aspirin-induced asthma. ( Dworski, R; Nizankowska, E; Szczeklik, A, 1990) |
| "Eight patients are described who fulfill the criteria for the triad of asthma, nasal polyposis, and aspirin hypersensitivity who have been treated with oral chrysotherapy from 7 to 17 months." | 9.06 | Oral gold therapy in steroid-dependent asthma, nasal polyposis, and aspirin hypersensitivity. ( McNeil, DL, 1990) |
| "Ten aspirin (ASA)-sensitive patients with asthma underwent double-blind, placebo-controlled oral challenges with salsalate followed by ASA-sensitive confirmatory challenges." | 9.06 | Salsalate cross-sensitivity in aspirin-sensitive patients with asthma. ( Goldlust, MB; Hougham, AJ; Schrank, PJ; Stevenson, DD; Wilson, RR, 1990) |
| "Inhalation of an aerosolized solution of lysine-aspirin has previously been described as a safer technique than oral challenge with aspirin for the diagnosis of aspirin-sensitive asthma." | 9.06 | Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine. ( Foord, R; Holgate, ST; Phillips, GD, 1989) |
| "Inhibition of prostacyclin biosynthesis by aspirin might be expected to promote asthmatic attacks in aspirin-intolerant patients." | 9.06 | The effect of prostacyclin on asthma precipitated by aspirin. ( Czerniawska-Mysik, G; Nizankowska, E; Szczeklik, A, 1987) |
| "One hundred and fifty-six German, Italian and Polish patients with confirmed aspirin-induced asthma underwent open oral challenges with increasing doses of tartrazine up to 25 mg." | 9.06 | Intolerance to tartrazine in aspirin-induced asthma: results of a multicenter study. ( Bianco, S; Damonte, C; Juhl, E; Menz, G; Robuschi, M; Schmitz-Schumann, M; Serwonska, M; Szczeklik, A; Virchow, C, 1988) |
| "Inhibition of prostacyclin biosynthesis by aspirin might be expected to promote asthmatic attacks in aspirin-intolerant patients." | 9.06 | Lack of effect of i.v. prostacyclin on aspirin-induced asthma. ( Czerniawska-Mysik, G; Nizankowska, E; Szczeklik, A, 1986) |
| "Adverse reactions to aspirin in asthmatic patients have been widely described in the past." | 9.05 | Failure of children with asthma to respond to daily aspirin therapy. ( Cummings, NP; Morris, HG; Strunk, RC, 1983) |
| "In six adult patients with bronchial asthma aspirin in a single dose of 0." | 9.05 | Asthma improved by aspirin-like drugs. ( Nizankowska, E; Szczeklik, A, 1983) |
| "Because aspirin (ASA) is often reported to have an adverse effect on pulmonary function in children with chronic asthma, acetaminophen is commonly used as an ASA substitute in these children." | 9.05 | Adverse pulmonary responses to aspirin and acetaminophen in chronic childhood asthma. ( Fischer, TJ; Gartside, PS; Guilfoile, TD; Kearns, GL; Kesarwala, HH; Moomaw, CJ; Winant, JG, 1983) |
| "Eight asthmatics with respiratory intolerance to NSAIDs and two subjects (one asthmatic, one healthy) only sensitive (asthma) to pyrazolone drugs were challenged under single-blind conditions with a new NSAID, carprofen." | 9.05 | Tolerance of carprofen in patients with asthma caused by non-steroidal anti-inflammatory drugs. ( Bianco, S; Pasargiklian, M; Robuschi, M; Simone, P; Vaghi, A, 1985) |
| "We studied the effects of intravenous injection of hydrocortisone, as compared to its solvent, in 31 patients with aspirin-induced asthma." | 9.05 | Hydrocortisone and airflow impairment in aspirin-induced asthma. ( Czerniawska-Mysik, G; Nizankowska, E; Sek, S; Szczeklik, A, 1985) |
| "Oral challenge tests with acetylsalicylic acid, tartrazine or benzoic acid were performed in 7 intolerant asthmatic patients after a 3-day treatment with either orally taken ketotifen (1 mg twice daily) or inhaled disodium cromoglycate (20 mg four times daily) at random." | 9.04 | Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. ( Wüthrich, B, 1979) |
| "The control of asthma by therapy with cromolyn sodium was studied in 28 adults with late-onset asthma associated with hypersensitivity to aspirin and nasal polyps." | 9.04 | Cromolyn sodium in the treatment of asthma associated with aspirin hypersensitivity and nasal polyps. ( Gwin, E; Kerby, GR; Ruth, WE, 1977) |
| "Forty-five patients with moderately severe perennial bronchial asthma were challenged by ingestion of: acetylsalicyclic acid (ASA); 4 azo dyes (tartrazine, sunset yellow, amaranth, and ponceau); 3 non-azo dyes (erythrosine, brilliant blue, and indigotin); sodium benzoate (NaB); parahydroxybenzoic acid (OHBA); butylated hydroxyanisole (BHA); and butylated hydroxytoluene (BHT)." | 9.04 | Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics. ( Hoffman, M; Nelson, HS; Raine, DA; Weber, RW, 1979) |
| "Oral aspirin challenge was used to detect unrecognized aspirin intolerance in a select group of 50 asthmatic patients who denied aspirin intolerance." | 9.04 | Refractory period to aspirin in a patient with aspirin-induced asthma. ( Lockey, RF; Zeiss, CR, 1976) |
| "Most previously reported individuals with acetylsalicylic acid (aspirin, ASA)-induced asthma have been adults." | 9.04 | Aspirin intolerance in chronic childhood asthma: Detected by oral challenge. ( Coulson, A; Rachelefsky, GS; Siegel, SC; Stiehm, ER, 1975) |
| "In four subjects with exercise-induced asthma, aspirin and placebo were administered prior to exercise in a double blind study." | 9.04 | Aspirin and exercise-induced asthma. ( Hamosh, P; Taveira da Silva, AM, 1976) |
| "The prevalence and mean provocative dose of oral aspirin (MPDA) triggering respiratory reactions in people with asthma have been inconsistently reported, and the relationship between NSAID-exacerbated respiratory disease (NERD) and asthma morbidity was less well quantified." | 8.91 | NSAID-exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity. ( Donnan, PT; Guthrie, B; Jackson, C; Lipworth, BJ; Morales, DR; Santiago, VH, 2015) |
| "Aspirin-exacerbated diseases are important examples of drug hypersensitivities and include aspirin-exacerbated respiratory disease (AERD), aspirin- or non-steroidal anti-inflammatory drug (NSAID)-induced urticaria/angioedema, and aspirin- or NSAID-induced anaphylaxis." | 8.91 | Aspirin-Exacerbated Diseases: Advances in Asthma with Nasal Polyposis, Urticaria, Angioedema, and Anaphylaxis. ( Buchheit, K; Cahill, KN; Stevens, W, 2015) |
| "Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently coexist and are always present in patients with aspirin exacerbated respiratory disease (AERD)." | 8.90 | Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity. ( Machado-Carvalho, L; Picado, C; Roca-Ferrer, J, 2014) |
| "NSAIDs-including aspirin (ASA)-that inhibit cyclooxygenase (COX)-1 induce nonallergic hypersensitivity reactions consisting of attacks of rhinitis and asthma." | 8.85 | Aspirin sensitivity and desensitization for asthma and sinusitis. ( Stevenson, DD, 2009) |
| "The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma." | 8.85 | Gene-expression signatures of nasal polyps associated with chronic rhinosinusitis and aspirin-sensitive asthma. ( Metson, R; Platt, M; Stankovic, K, 2009) |
| "Leukotriene overproduction is the major characteristic of aspirin-intolerant asthma (AIA)." | 8.84 | Pharmacogenetics of aspirin-intolerant asthma. ( Choi, JH; Hur, GY; Kim, SH; Park, HS, 2008) |
| "Aspirin and other nonsteroidal anti-inflammatory drugs that inhibit COX-1 induce unique nonallergic reactions, consisting of attacks of rhinitis and asthma." | 8.83 | Clinical and pathologic perspectives on aspirin sensitivity and asthma. ( Stevenson, DD; Szczeklik, A, 2006) |
| "The relationship of aspirin sensitivity to urticaria is complex." | 8.82 | Aspirin sensitivity and urticaria. ( Grattan, CE, 2003) |
| "In some asthmatic individuals, aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygen-ase 1 (COX-1) exacerbate the condition." | 8.82 | Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. ( Stevenson, DD; Szczeklik, A, 2003) |
| "Aspirin (ASA) is an important cause of asthma so that ASA induced asthma (AIA) is considered a disease." | 8.82 | [Asthma and aspirin]. ( Frati, F; Gani, F; Marcucci, F; Schiappoli, M; Senna, G, 2003) |
| "To review the safety of cyclooxygenase-2 (COX-2) inhibitors in asthma patients with aspirin hypersensitivity." | 8.82 | Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity. ( Fernández, C; West, PM, 2003) |
| "Aspirin-induced asthma (AIA) is a distinct clinical entity characterised by hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) typically occurring in the form of asthma and severe rhinosinusitis." | 8.82 | [Asthma with hypersensitivity to aspirin]. ( Nizankowska-Mogilnicka, E, 2003) |
| "To reassess the prevalence of aspirin induced asthma and other issues related to the syndrome." | 8.82 | Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. ( Costello, J; Hodge, L; Jenkins, C, 2004) |
| "Aspirin (acetylsalicylic acid)-induced asthma (AIA) consists of the clinical triad of asthma, chronic rhinosinusitis with nasal polyps, and precipitation of asthma and rhinitis attacks in response to aspirin and other NSAIDs." | 8.82 | Aspirin-induced asthma: clinical aspects, pathogenesis and management. ( Hamad, AM; Knox, AJ; Sutcliffe, AM, 2004) |
| "To provide a diagnostic strategy for evaluating and treating patients with aspirin sensitivity, with additional consideration for issues specific to patients with coronary artery disease (CAD)." | 8.82 | Aspirin sensitivity: implications for patients with coronary artery disease. ( Gollapudi, RR; Simon, RA; Stevenson, DD; Teirstein, PS, 2004) |
| "Aspirin-sensitive asthma is a common and often underdiagnosed disease affecting up to 20% of the adult asthmatic population." | 8.82 | Aspirin-sensitive asthma. ( Gillis, D; Kette, F; Morwood, K; Smith, W, 2005) |
| "In 2-23% of adults with asthma, and rarely in children with asthma, aspirin (acetylsalicylic acid) and non-steroidal anti-inflammatory drugs (NSAIDs) cause asthma exacerbations." | 8.82 | Pathogenesis and management of aspirin-intolerant asthma. ( Haahtela, T; Kohno, S; Matsuse, H; Obase, Y; Shimoda, T, 2005) |
| "Available clinical data on aspirin-sensitive asthma (ASA) indicate that ASA patients have certain disturbances in the nervous, endocrine, immune and other body systems." | 8.81 | Aspirin-sensitive asthma due to diffuse neuroendocrine system pathology. ( Evsyukova, HV, 2002) |
| "Aspirin-sensitive asthmatics experience a wide variety of symptoms, ranging from rhinitis to life-threatening bronchospasms, after the ingestion of aspirin or nonsteroidal antiinflammatory drugs (NSAIDs)." | 8.81 | Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics. ( Pontikes, PJ; Volkman, JA, 2002) |
| "In about 10% of adult patients with asthma, aspirin and other nonsteroidal anti-inflammatory drugs precipitate attacks of dyspnoea." | 8.81 | A new insight into aspirin-induced asthma. ( Jawien, J, 2002) |
| "Interesting findings relating to aspirin-induced asthma recently emerged." | 8.81 | Aspirin-induced rhinitis and asthma. ( Nizankowska, E; Sanak, M; Swierczynska, M; Szczeklik, A, 2001) |
| "We described asthma with sensitivity to aspirin and other nonsteroidal anti-inflammatory drugs (NSAID)." | 8.81 | [Asthma with aspirin intolerance]. ( Krasnowska, M, 2002) |
| "In the United States, the documented prevalence of childhood asthma has increased since 1970, but the rate of this increase accelerated upward beginning in the early 1980s when the use of pediatric aspirin decreased." | 8.80 | Hypothesis: decreased use of pediatric aspirin has contributed to the increasing prevalence of childhood asthma. ( Busse, WW; Lemanske, RF; Varner, AE, 1998) |
| "In some patients with asthma, aspirin (ASA) and all nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase enzymes (cyclooxygenase-1 and -2) precipitate asthmatic attacks and naso-ocular reactions." | 8.80 | Aspirin-induced asthma: advances in pathogenesis and management. ( Stevenson, DD; Szczeklik, A, 1999) |
| "Aspirin-sensitive rhinosinusitis is a non-allergic, non-infectious perennial eosinophilic rhinitis starting in middle age and rarely seen in children." | 8.79 | Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis. ( Schapowal, AG; Schmitz-Schumann, M; Simon, HU, 1995) |
| "Aspirin-induced asthma is a distinct clinical syndrome which affects about 10% of adult asthmatics." | 8.78 | The cyclooxygenase theory of aspirin-induced asthma. ( Szczeklik, A, 1990) |
| "Patients with asthma and nasal polyps have been warned to avoid aspirin because of a tendency to develop hypersensitivity reactions." | 8.77 | Desensitization to aspirin in aspirin-sensitive patients with rhino-sinusitis and asthma: a review. ( Knight, A, 1989) |
| "Aspirin-induced asthma (AIA) is a distinct clinical syndrome, present in about 10% of adult asthmatics." | 8.77 | Aspirin-induced asthma: new insights into pathogenesis and clinical presentation of drug intolerance. ( Szczeklik, A, 1989) |
| "The historic triad of bronchial asthma, nasal polyposis, and intolerance to aspirin and related chemicals, recently designated as Samter's syndrome, is an inflammatory condition of unknown etiology and pathogenesis." | 8.77 | Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter's syndrome. ( Zeitz, HJ, 1988) |
| "Aspirin intolerance is particularly common in asthmatic patients who additionally have chronic rhinitis and/or nasal polyps." | 8.77 | Aspirin-sensitive asthma. ( Mathews, KP; McLean, JA; Slepian, IK, 1985) |
| "Aspirin-exacerbated respiratory disease (AERD) is a phenotype of severe asthma, but its disease course has not been well documented compared with that of aspirin-tolerant asthma (ATA)." | 8.31 | Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort. ( Kim, C; Lee, E; Lee, HY; Lee, Y; Park, HS; Park, RW; Woo, SD; You, SC, 2023) |
| " The coexistence of CRS, bronchial asthma and aspirin intolerance (aspirin triad) is an adverse prognostic factor with higher risk of recurrences." | 7.91 | Analysis of the impact of bronchial asthma and hypersensitivity to aspirin on the clinical course of chronic sinusitis with nasal polyps. ( Dąbrowska, K; Fendler, W; Pagacz, K; Pietruszewska, W; Podwysocka, M, 2019) |
| "The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity." | 7.88 | [Is celecoxib a safe alternative for the Fernand Widal syndrome?] ( De Blay, F; Guenard-Bilbaut, L; Metz-Favre, C; Schaller, A, 2018) |
| "Aspirin exacerbated asthma (AEA) affects approximately 10% of the asthmatic population." | 7.88 | Asthma exacerbation by aspirin and chemical additives: use of a nucleotide template model to investigate potential mechanisms. ( Williams, WR, 2018) |
| "Aspirin hypersensitivity associated with chronic rhinosinusitis-with or without nasal polyposis-and asthma resistant to conventional therapy defines the aspirin-exacerbated respiratory disease (AERD)." | 7.85 | Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria. ( Cutrera, R; Di Marco, A; Porcaro, F, 2017) |
| "In utero exposure to aspirin was associated with an increased risk of childhood asthma (adjusted odds ratio [aORs] = 1." | 7.83 | In Utero Exposure to Aspirin and Risk of Asthma in Childhood. ( Bao, J; Bao, Y; Chu, S; Huang, L; Yu, H; Zhang, J, 2016) |
| " In aspirin exacerbated respiratory disease (AERD), asthmatic symptoms are precipitated by ingestion of non-steroid anti-inflammatory drugs capable for pharmacologic inhibition of cyclooxygenase-1 isoenzyme." | 7.81 | Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics. ( Celejewska-Wójcik, N; Gielicz, A; Januszek, R; Kaszuba, M; Mastalerz, L; Oleś, K; Plutecka, H; Sanak, M; Stręk, P; Wójcik, K, 2015) |
| "Aspirin-exacerbated respiratory disease (AERD) has attracted a great deal of attention because of its association with increased asthma severity." | 7.80 | Plasma apolipoprotein H levels are different between aspirin induced respiratory diseases and aspirin tolerant asthma. ( Heo, JS; Kim, HJ; Moon, KY; Park, CS; Park, JS, 2014) |
| " Thus, functional alterations of the RAB1A gene may contribute to aspirin intolerance in asthmatic sufferers." | 7.80 | Association analysis of member RAS oncogene family gene polymorphisms with aspirin intolerance in asthmatic patients. ( Chang, HS; Choi, IS; Heo, JS; Kim, MK; Lee, JU; Park, BL; Park, CS; Park, JS; Shin, HD, 2014) |
| "Aspirin-intolerant asthma is a unique clinical syndrome characterized by acute bronchoconstriction following the administration of aspirin and/or non-steroidal anti-inflammatory drugs." | 7.79 | Aspirin-intolerant asthma in the Korean population: prevalence and characteristics based on a questionnaire survey. ( Chang, YS; Cho, SH; Cho, YJ; Cho, YS; Choi, BW; Jang, AS; Kim, SH; Kim, TB; Lee, JH; Moon, HB; Moon, JY; Nahm, DH; Park, CS; Park, JW; Yoon, HJ, 2013) |
| "We compared outpatients with difficult-to-treat asthma (DTA; n = 486) in a tertiary hospital for allergic diseases in central Japan with those with controlled severe asthma (n = 621) with respect to clinical factors including body mass index (BMI) and aspirin intolerance using multivariate logistic regression analysis stratified by gender and atopic phenotype." | 7.78 | Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women. ( Akiyama, K; Fukutomi, Y; Hasegawa, M; Higashi, N; Mori, A; Nakamura, H; Ono, E; Oshikata, C; Sekiya, K; Taniguchi, M; Tanimoto, H; Tsuburai, T, 2012) |
| "Nine common SNPs were genotyped in 93 AERD patients and 96 aspirin-tolerant asthma (ATA) controls." | 7.78 | Potential association of DDR1 genetic variant with FEV1 decline by aspirin provocation in asthmatics. ( Bae, JS; Cho, SH; Choi, BW; Choi, IS; Kim, JH; Kim, JY; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Pasaje, CF; Shin, HD; Uh, ST, 2012) |
| "There is no in vitro test to diagnose aspirin-intolerant asthma (AIA)." | 7.78 | Challenge of isolated sputum cells supports in vivo origin of intolerance reaction to aspirin/non-steroidal anti-inflammatory drugs in asthma. ( Daham, K; Dahlén, B; Dahlén, SE; Delin, I; Gaber, F; Gyllfors, P; Higashi, A; Higashi, N; James, A; Kumlin, M; Lindeberg, A; Skedinger, M, 2012) |
| "Chronic rhinosinusitis (CRS) with nasal polyposis (NP) may be associated with hypersensitivity to nonsteroidal anti-inflammatory drugs, representing a syndrome of aspirin-exacerbated respiratory disease (AERD)." | 7.78 | Incidence of aspirin hypersensitivity in patients with chronic rhinosinusitis and diagnostic value of urinary leukotriene E4. ( Celejewska-Wójcik, N; Cybulska, A; Hartwich, P; Hydzik-Sobocińska, K; Januszek, R; Mastalerz, L; Nieckarz, R; Oleś, K; Sanak, M; Stręk, P; Szaleniec, J; Wójcik, K, 2012) |
| "Aspirin is the most commonly used antiplatelet agent in patients with coronary artery disease (CAD)." | 7.78 | Aspirin sensitivity and coronary artery disease: implications for the practicing cardiologist. ( Das, P; Lieberman, P; Pattanaik, D, 2012) |
| "Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin." | 7.77 | A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, IS; Hong, CS; Kim, JH; Kim, MK; Kim, Y; Koh, IS; Lee, JS; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| "In addition to the dysregulation of arachidonic acid metabolism in aspirin-intolerant asthma (AIA), aspirin acetylsalicylic acid (ASA) exerts effects on inflammation and immunity; however, many of these effects are unknown." | 7.77 | Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmatics. ( Byun, JY; Cheong, HS; Kim, MO; Lee, JY; Park, BL; Park, CS; Park, JS; Park, SM; Shin, HD, 2011) |
| "We sought to assess a vast platform of eicosanoids in different asthma phenotypes, including aspirin-intolerant asthma, by means of a recently developed analytic approach based on mass spectrometry." | 7.77 | Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype. ( Bochenek, G; Gielicz, A; Kaszuba, M; Niżankowska-Mogilnicka, E; Sanak, M; Szczeklik, A, 2011) |
| "Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of nasal polyps (NPs) and aspirin-intolerant asthma (AIA)." | 7.77 | Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthma. ( Alobid, I; Garcia-Garcia, FJ; Mullol, J; Pereda, J; Perez-Gonzalez, M; Picado, C; Pujols, L; Roca-Ferrer, J, 2011) |
| "Logistic regression analysis of RGS7BP gene polymorphisms in patients with AERD (n = 102) and aspirin-tolerant asthma (n = 429) revealed that a haplotype of block 3 consisting of rare alleles +98092 C>G, +98853 C>T, and +104450 T>G of the RGS7BP gene was associated with AERD." | 7.77 | Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients. ( Cho, SH; Choi, BW; Choi, IS; Hong, CS; Kim, MK; Lee, EH; Lee, JY; Lee, SH; Park, BL; Park, CS; Park, JS; Park, SM; Park, SW; Shin, HD; Uh, ST, 2011) |
| "The present study inluded 22 patients presenting either with very severe or moderately severe aspirin triad 17 of whom suffered exacerbation of chronic polypous suppurative rhinosinusitis." | 7.77 | [The treatment of polypous suppurative rhinosinusitis in the patients presenting with the severe and moderate aspirin triad]. ( Riabova, MA; Shumilova, NA, 2011) |
| "Theophylline is commonly used to treat severe asthma and chronic obstructive pulmonary disease (COPD) characterized by non-eosinophilic inflammation." | 7.76 | Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma. ( Choi, DS; Choi, JP; Gho, YS; Jeon, SG; Kim, YK; Kim, YS; Moon, HG; Yoon, CM, 2010) |
| " Aspirin-intolerant asthma and anaphylaxis accompany PGD(2) overproduction, possibly associated with mast cell activation via the COX pathway." | 7.76 | Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers. ( Akiyama, K; Fukutomi, Y; Higashi, N; Kajiwara, K; Mita, H; Ono, E; Sekiya, K; Taniguchi, M; Tanimoto, H; Yamaguchi, H, 2010) |
| "These findings suggest that ASA changes Th17-type into Th2-type inflammation mainly via the adenosine and uric acid metabolic pathway in the lung." | 7.76 | Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung. ( Gyu Jeon, S; Kim, YK; Kim, YS; Moon, HG; Oh, SY; Song Gho, Y; Tae, YM; Zhu, Z, 2010) |
| "According to the GA2LEN recommendations, nasal challenge test with lysine-aspirin should be performed only in patients with severe asthma, because the sensitivity of this test has been lower than in bronchial and oral challenge tests." | 7.76 | Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis. ( Dahlén, B; Ehnhage, A; Juto, JE; Kölbeck, KG; Stjärne, P, 2010) |
| "Aspirin-intolerant asthma (AIA) is characterized by severe asthmatic attack after ingestion of aspirin and/or non-steroidal anti-inflammatory drugs." | 7.76 | Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics. ( Cho, SH; Choi, BW; Choi, IS; Choi, JS; Hong, CS; Kim, MK; Kim, YH; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, JS; Park, SM; Shin, HD; Uh, ST, 2010) |
| "Aspirin-intolerant asthma (AIA) occurs from asthma exacerbation after exposure to aspirin." | 7.76 | Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Chun, JY; Kim, JH; Kim, MK; Kim, Y; Kim, YH; Lee, JS; Park, BL; Park, CS; Park, JS; Park, TJ; Pasaje, CF; Shin, HD; Uh, ST; Yoon, SH, 2010) |
| " Thus, functional alterations of the NAT gene may contribute to the risk of aspirin-intolerant asthma." | 7.76 | Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics. ( Chang, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jung, S; Kim, JM; Kim, MK; Kim, MO; Kim, YH; Lee, EH; Lee, SH; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST, 2010) |
| "Many patients with aspirin-induced asthma have severe methacholine airway hyperresponsiveness (AHR), suggesting a relationship between aspirin and methacholine in airway response." | 7.76 | Airway responsiveness to inhaled aspirin is influenced by airway hyperresponsiveness in asthmatic patients. ( Choi, IS; Han, ER; Kim, CS; Kim, DE; Kim, S; Kim, YJ; Park, DJ, 2010) |
| "Aspirin affects interleukin-4 (IL-4) synthesis; however, the genetic role of IL-4 has not been evaluated in asthmatics with aspirin hypersensitivity." | 7.76 | Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity. ( Cho, SH; Choi, BW; Choi, IS; Chung, IY; Hong, CS; Jang, AS; Kang, JH; Kim, BS; Kim, MK; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST; Uhm, TG, 2010) |
| "Aspirin-intolerant asthma (AIA) is a rare condition that is characterized by the development of bronchoconstriction in asthmatic patients after ingestion of non-steroidal anti-inflammatory drugs including aspirin." | 7.76 | Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jang, AS; Kim, JH; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Shin, HD; Uh, ST, 2010) |
| "Patients with aspirin-sensitive asthma and/or nasal polyps (n = 40), patients with aspirin-tolerant asthma and/or nasal polyps (n = 13) and healthy volunteers (n = 26) were included." | 7.75 | Cellular allergen stimulation test with acetylsalicylic acid-lysine is not a useful test to discriminate between asthmatic patients with and without acetylsalicylic acid sensitivity. ( Bavbek, S; Birben, E; Dursun, AB; Kalayci, O; Misirligil, Z, 2009) |
| "Among the patients with asthma, polymorphism at -1082A/G was significantly associated with the phenotype of aspirin-intolerant asthma, AIA (P = 0." | 7.75 | Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. ( Cho, BY; Kim, SH; Lee, HN; Park, HS; Yang, EM; Ye, YM, 2009) |
| "Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp)." | 7.75 | Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma. ( Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Kurono, Y; Matsune, S; Sano, Y; Sekigawa, T; Tajima, A, 2009) |
| "Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks." | 7.74 | Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008) |
| " We hypothesized that the three subsets of the FCER1 gene may play a role in the development of the aspirin-intolerant asthma (AIA) phenotype and analyzed these genetic polymorphisms in association with clinical parameters in AIA patients." | 7.74 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma. ( Cho, BY; Hur, GY; Kim, SH; Palikhe, NS; Park, HS; Ye, YM, 2008) |
| "Aspirin provocation tests were performed in 667 asthmatic patients and changes in FEV(1) were used to categorize patients as ATA or AIA." | 7.74 | Obesity in aspirin-tolerant and aspirin-intolerant asthmatics. ( Jang, AS; Kim, DJ; Kim, YH; Park, CS; Park, HS; Park, JS; Park, SW; Seo, KH; Uh, ST, 2008) |
| "Aspirin-intolerant asthma (AIA) refers to the development of bronchoconstriction in asthmatic individuals following the ingestion of aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs)." | 7.74 | Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. ( Chang, HS; Cho, SH; Choi, IS; Chung, IY; Kim, MK; Kim, TH; Nam, BY; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Rhim, T; Shin, HD, 2008) |
| " Clinical data show that mixed COX-1/COX-2 inhibitors such as aspirin, but not COX-2 selective inhibitors such as rofecoxib, induce bronchoconstriction and asthma in sensitive individuals." | 7.74 | COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma. ( Harrington, LS; Lucas, R; McMaster, SK; Mitchell, JA; Moreno, L; Scadding, G; Warner, TD, 2008) |
| "Platelets are involved in the pathogenesis of aspirin-induced asthma (AIA)." | 7.74 | Selenium status in patients with aspirin-induced asthma. ( Hassan, AM, 2008) |
| "A diagnosis of aspirin-intolerant asthma requires aspirin provocation in specialist clinics." | 7.74 | Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma. ( Daham, K; Dahlén, B; Dahlén, SE; Delin, I; Gaber, F; Gülich, A; Gyllfors, P; Higashi, A; Higashi, N; James, A; Kumlin, M; Nord, M; Skedinger, M, 2008) |
| "Rhinosinusitis is highly associated with aspirin-intolerant asthma (AIA)." | 7.74 | Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients. ( Holloway, JW; Kim, SH; Park, CS; Park, HS; Shin, HD, 2007) |
| "In an observational cohort study, women who self-selected for frequent aspirin use developed less newly diagnosed asthma than women who did not take aspirin." | 7.74 | Aspirin and decreased adult-onset asthma: randomized comparisons from the physicians' health study. ( Barr, RG; Buring, JE; Gaziano, JM; Hennekens, CH; Kurth, T; Stampfer, MJ, 2007) |
| "Of 147 patients who reported seeking acute medical care for their historical aspirin/NSAID-induced asthma attacks, 101 (69%) were treated in an emergency department and released, and 46 (31%) required hospitalization." | 7.74 | The relationship between historical aspirin-induced asthma and severity of asthma induced during oral aspirin challenges. ( Simon, RA; Stevenson, DD; Williams, AN; Woessner, KM, 2007) |
| "Genetic predisposition is linked to the pathogenesis of aspirin-intolerant asthma." | 7.74 | Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma. ( Bahn, JW; Chang, YS; Jee, YK; Kim, SH; Kim, YK; Lee, JE; Min, KU; Park, HS; Park, HW; Shin, ES; Ye, YM, 2007) |
| "The study included 30 patients with ASA, 30 patients with aspirin-tolerant asthma (ATA) and 30 HS serving as controls." | 7.74 | Alternative splicing of cyclooxygenase-1 gene: altered expression in leucocytes from patients with bronchial asthma and association with aspirin-induced 15-HETE release. ( Borowiec, M; Kowalski, ML; Kurowski, M; Pawliczak, R, 2007) |
| " Analysis of bronchial biopsies and bronchial epithelial cells in culture conducted so far gave conflicting results of expression pattern of these enzymes in healthy subjects and asthmatics patients, with and without aspirin hypersensitivity." | 7.74 | Deficiency of cyclooxygenases transcripts in cultured primary bronchial epithelial cells of aspirin-sensitive asthmatics. ( Nizankowska-Mogielnicka, E; Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A; Woś, M, 2007) |
| "The study groups consisted of 22 subjects with AERD, 22 subjects with ATA and 10 volunteers without asthma and aspirin sensitivity." | 7.74 | Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity. ( Celik, GE; Erkekol, FO; Melli, M; Misirligil, Z, 2007) |
| "Leukotriene receptor antagonists (LTRA), such as montelukast, have been used as a first-line treatment for patients with aspirin-intolerant asthma (AIA)." | 7.74 | CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients. ( Hur, GY; Kim, SH; Lee, HY; Lee, SK; Park, HS; Sampson, AP; Ye, YM, 2007) |
| "In aspirin-sensitive patients with asthma, bronchial obstruction induced by oral aspirin may be associated with extrabronchial symptoms, suggesting the systemic character of the response." | 7.74 | Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. ( Bienkiewicz, B; Grzegorczyk, J; Kowalski, ML; Makowska, JS; Wozniak, M, 2008) |
| "The aim of the investigation was to study melatonin production in thrombocytes and their functional activity in correlation with 6-sulfatoximelatonin (6-SOM) urinary excretion in patients with aspirin-induced bronchial asthma (AIBA)." | 7.74 | [Melatonin production in thrombocytes and their functional activity in patients with aspirin asthma]. ( Evsiukova, EV; Kveshnoĭ, IM; Muraia, EV; Zubzhitskaia, LB, 2007) |
| "Aspirin-intolerant asthma (AIA), a major clinical presentation of aspirin hypersensitivity, affects 10% of adult asthmatics." | 7.74 | Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics. ( Cho, BY; Jeong, HH; Kim, M; Kim, SH; Lee, HY; Lee, J; Park, HS; Wee, K, 2008) |
| "To identify genes whose expression is most characteristic of chronic rhinosinusitis and aspirin-sensitive asthma through genome-wide transcriptional profiling of nasal polyp tissue." | 7.74 | Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma. ( Goldsztein, H; Metson, R; Platt, MP; Reh, DD; Stankovic, KM, 2008) |
| "The mechanism of aspirin (acetylsalicylic acid: ASA) hypersensitivity in asthmatic patients is related to arachidonic acid metabolism abnormalities, and specific triggering by ASA of 15-hydroxyeicosatetraenoic acid (15-HETE) generation was observed in leucocytes from aspirin-sensitive (AS) but not from aspirin-tolerant (AT) asthmatics." | 7.74 | Involvement of 15-lipoxygenase and prostaglandin EP receptors in aspirin-triggered 15-hydroxyeicosatetraenoic acid generation in aspirin-sensitive asthmatics. ( Bienkiewicz, B; Jedrzejczak-Czechowicz, M; Kowalski, ML; Lewandowska-Polak, A, 2008) |
| "Aspirin-sensitivity, asthma, and nasal polyposis (NP) comprise the clinical entity of Samter's triad." | 7.74 | Sinonasal outcomes after endoscopic sinus surgery in asthmatic patients with nasal polyps: a difference between aspirin-tolerant and aspirin-induced asthma? ( Awad, OG; Fasano, MB; Graham, SM; Lee, JH, 2008) |
| "Widal disease is characterized by symptomatic triad of aspirin intolerance, nasal polyposis and asthma." | 7.73 | [Widal triad (Asthma-Nasal polyposis-aspirin intolerance): an inflammatory metabolism abnormality]. ( Leimgruber, A, 2005) |
| " Nasal polyp tissues were obtained from 29 patients [including nine with aspirin (ASA)-hypersensitivity and 12 with bronchial asthma] undergoing polypectomy for nasal obstruction." | 7.73 | Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma. ( Danilewicz, M; Jankowski, A; Kowalski, ML; Lewandowska-Polak, A; Pawliczak, R; Ptasińska, A; Wagrowska-Danilewicz, M; Woźniak, J, 2005) |
| "Aspirin-sensitive asthma, aspirin-intolerant asthma, aspirin- (or non-steroidal anti-inflammatory drug [NSAID]) exacerbated respiratory disease are terms for a disorder commonly described as affecting adults aged > 30y." | 7.73 | A teenager with severe asthma exacerbation following ibuprofen. ( Palmer, GM, 2005) |
| "1 encodes a receptor for CYSLTs, potent biological mediators in the pathogenesis of asthma, particularly that associated with aspirin intolerance (AIA)." | 7.73 | Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics. ( Chang, HS; Choi, JH; Choi, YH; Kim, LH; Lee, JH; Lee, YM; Park, BL; Park, CS; Park, HS; Park, JS; Shin, HD, 2005) |
| "Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not." | 7.73 | Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005) |
| "To investigate the impact of nasal polyps on quality of life compared with the Spanish general population using the SF-36 questionnaire; and to evaluate the impact of asthma and aspirin sensitivity on quality of life in patients with nasal polyposis." | 7.73 | The impact of asthma and aspirin sensitivity on quality of life of patients with nasal polyposis. ( Alobid, I; Benítez, P; Bernal-Sprekelsen, M; Guilemany, JM; Mullol, J; Picado, C, 2005) |
| " Multiple regression analysis confirmed that aspirin-intolerant asthma (AIA) was strongly associated with NFA." | 7.73 | Contribution of aspirin-intolerant asthma to near fatal asthma based on a questionnaire survey in Niigata Prefecture, Japan. ( Arakawa, M; Gejyo, F; Hasegawa, T; Kondoh, A; Koya, T; Suzuki, E; Terada, M; Yoshimine, F; Yoshizawa, H, 2005) |
| "We sought to investigate the role of aspirin-exacerbated respiratory disease (AERD) as a risk factor for the development of irreversible airway obstruction." | 7.73 | Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma. ( Bleecker, ER; Borish, L; Deniz, YM; Haselkorn, T; Mascia, K; Miller, DP, 2005) |
| "Aspirin-induced asthma (AIA) is a distinct clinical syndrome that affects up to 10% of adults with asthma." | 7.73 | Complement C3a and C4a increased in plasma of patients with aspirin-induced asthma. ( Cho, SY; Choi, YS; Kim, SH; Lee, SH; Min, JW; Paik, YK; Park, CS; Rhim, T, 2006) |
| "GSTP1 Ile105Val polymorphism was determined using a single based extension method in 88 AIA subjects and compared to 154 aspirin-tolerant asthma (ATA) subjects and 119 normal healthy controls (NC) recruited from the Korean population." | 7.73 | Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma. ( Kim, SH; Lee, JH; Lee, YM; Nahm, DH; Oh, JM; Park, CS; Park, HS; Shin, HD; Suh, CH, 2005) |
| "Eosinophilic infiltration of airway tissue is a central feature of aspirin-induced asthma (AIA)." | 7.73 | Comparison of plasma eotaxin family level in aspirin-induced and aspirin-tolerant asthma patients. ( Jang, AS; Lee, JH; Lee, SH; Min, JW; Park, CS; Park, SM; Park, SW, 2005) |
| "Aspirin-intolerant asthma (AIA) is a distinct clinical syndrome that refers to the development of bronchoconstriction in asthmatic individuals following the ingestion of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)." | 7.73 | Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population. ( Bae, JS; Choi, JH; Kim, SH; Nahm, DH; Park, HS; Suh, CH; Yu, HL, 2006) |
| "The pathogenesis of aspirin (acetylsalicylic acid, ASA)-intolerant urticaria (AIU) is still poorly understood but it has recently been suggested that it is associated with the overproduction of leukotriene (LT)." | 7.73 | Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population. ( Choi, JH; Ha, EH; Holloway, JW; Kim, SH; Nahm, DH; Park, CS; Park, HS; Suh, CH, 2005) |
| "Hypersensitivity to aspirin usually takes the form of a clinical syndrome combining chronic rhinitis, nasal polyposis and asthma attacks that are exacerbated by aspirin or other non steroidal anti-inflammatory drugs (NSAIDs)." | 7.73 | [New pathophysiological concepts on aspirin hypersensitivity (Widal syndrome); diagnostic and therapeutic consequences]. ( de Weck, A; Gamboa, P; Sanz, ML, 2005) |
| " Urinary leukotriene E4 concentration (LTE4), that reflects the whole body production of cysteinil-leukotrienes, is particularly increased in patients with aspirin-intolerant asthma (AIA)." | 7.73 | Aspirin induced asthma (AIA) with nasal polyps has the highest basal LTE4 excretion: a study vs AIA without polyps, mild topic asthma, and normal controls. ( Dal Negro, RW; Facchini, FM; Micheletto, C; Tognella, S; Visconti, M, 2006) |
| " CysLTR1-selective antagonists have anti-bronchoconstrictive and anti-inflammatory effects in asthma, particularly aspirin-intolerant asthma (AIA)." | 7.73 | Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males. ( Kim, SH; Kim, YS; Nahm, DH; Oh, JM; Palmer, LJ; Park, HS; Suh, CH, 2006) |
| "Several studies have suggested the involvement of an autoimmune mechanism in aspirin (ASA)-intolerant asthma." | 7.73 | Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation. ( Choi, JH; Kim, SH; Nahm, DH; Park, HS; Suh, CH; Ye, YM, 2006) |
| "By the first 6 months of aspirin treatment, there were significant reductions in sinus infections and numbers of short courses of prednisone and improvements in sense of smell and general assessment of nasal-sinus and asthma symptoms (P <." | 7.72 | Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. ( Berges-Gimeno, MP; Simon, RA; Stevenson, DD, 2003) |
| "To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level using the automated fluorometric analyzer were observed in 13 aspirin (ASA)-sensitive asthma subjects (group I: 7 early responders and group II: 6 dual responders) during lysine aspirin bronchoprovocation test (L-ASA BPT)." | 7.72 | Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients. ( Kim, SS; Lee, SK; Lee, YM; Nahm, DH; Park, HS; Yoon, HJ, 2003) |
| "We examined whether a decreased activity of nuclear factor(NF)-kappaB), a transcriptional regulator of cyclooxygenase-2 (COX-2), could account for down-regulation of COX-2 in nasal polyps of aspirin-sensitive asthmatics." | 7.72 | Nuclear factor-kappaB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics. ( Benitez, P; Bioque, G; Bulbena, O; Mullol, J; Picado, C; Pujols, L; Roca-Ferrer, J, 2003) |
| "We sought to determine blood and urinary levels of 9alpha,11beta-PGF(2), a major stable PGD(2) metabolite in 2 well-defined phenotypes of asthma, aspirin-induced asthma (AIA) and aspirin-tolerant asthma (ATA), and in healthy control subjects and to study the effects of aspirin on PGD(2) release." | 7.72 | A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. ( Bochenek, G; Nagraba, K; Nizankowska, E; Szczeklik, A, 2003) |
| " The cells were isolated from 3 groups of subjects: nonasthmatic patients (n = 10), patients with aspirin-tolerant asthma (ATA, n = 9), and patients with aspirin-intolerant asthma (AIA, n = 7)." | 7.72 | Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. ( Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A, 2003) |
| "In 5-10% of adult patients with asthma, aspirin and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks." | 7.72 | Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Martín-García, C, 2003) |
| "Aspirin and other inhibitors of cyclo-oxygenase precipitate acute bronchospasm in about 10% of adult asthmatics." | 7.72 | Glutathione peroxidase activity in blood cells from aspirin-induced asthma patients. ( Hassan, AM, 2003) |
| "Although the mechanisms of aspirin-induced rhinosinusitis-asthma appear to be related to arachidonic acid abnormalities, only recently has a specific aspirin-triggered enhancement of 15-hydroxyeicosatetraenoic acid (15-HETE) generation in nasal polyp epithelial cells from aspirin-sensitive patients been demonstrated." | 7.72 | Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. ( Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A, 2003) |
| "We report the case of a 60 year old woman, suffering for 8 years from aspirin-induced asthma, having an airway infection of RSV-respiratory syncytial virus." | 7.72 | [Exacerbation of aspirin-induced asthma associated with RSV infection]. ( Filipowicz, E; Sanak, M, 2003) |
| "In group of patients with aspirin asthma basic concentration of LTE4 was 416." | 7.72 | [Urinary leukotriene E4 concentration in patients with bronchial asthma and intolerance of non-steroids anti-inflammatory drugs before and after oral aspirin challenge]. ( Chazan, R; Rubinsztajn, R; Wrońska, J, 2003) |
| "The urinary leukotriene E4 (U-LTE4) concentration is significantly increased in patients with aspirin-intolerant asthma (AIA)." | 7.72 | Clinical features of asthmatic patients with increased urinary leukotriene E4 excretion (hyperleukotrienuria): Involvement of chronic hyperplastic rhinosinusitis with nasal polyposis. ( Akiyama, K; Higashi, A; Higashi, N; Ishii, T; Kawagishi, Y; Mita, H; Osame, M; Taniguchi, M, 2004) |
| "The data from this study show that aspirin intolerance, HDM allergy, and asthma duration exceeding 10 years are major factors associated with severe asthma in outpatients." | 7.72 | Aspirin intolerance and allergy to house dust mites: important factors associated with development of severe asthma. ( Górski, P; Kuna, P; Kupczyk, M; Kupryś, I, 2004) |
| "Aspirin challenge of aspirin-intolerant asthma (AIA) patients causes a significant increase in leukotriene E4 (LTE4) concentration in urine." | 7.72 | Increase in urinary leukotriene B4 glucuronide concentration in patients with aspirin-intolerant asthma after intravenous aspirin challenge. ( Akiyama, K; Higashi, A; Higashi, N; Mita, H; Taniguchi, M, 2004) |
| "Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those with aspirin-intolerant asthma (AIA) than aspirin-tolerant asthma (ATA)." | 7.72 | Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma. ( Kim, HJ; Kim, SH; Nahm, DH; Park, HS; Sampson, AP; Suh, CH; Suh, YJ; Yoon, SH, 2004) |
| " Although the latter is conventionally used in nasal lysine-aspirin challenge, use of the former in aspirin-induced asthma (AIA) has never been evaluated." | 7.72 | Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma. ( Haggart, K; Lee, DK; Lipworth, BJ, 2004) |
| "Nasal polyps were obtained from 16 aspirin-tolerant patients with asthma/rhinitis (ATAR) and 18 aspirin-intolerant patients with asthma/rhinitis (AIAR) undergoing nasal polypectomy." | 7.72 | Dynamics of COX-2 in nasal mucosa and nasal polyps from aspirin-tolerant and aspirin-intolerant patients with asthma. ( Alobid, I; Mullol, J; Picado, C; Pujols, L; Roca-Ferrer, J; Xaubet, A, 2004) |
| "Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs)." | 7.72 | Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach. ( Goto, S; Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Jinnai, N; Kakihara, M; Koshino, T; Nakajima, T; Sakagami, T; Sano, Y; Sekigawa, T; Suzuki, N; Yoshida, K, 2004) |
| "We wondered whether application of expiratory breath condensate could facilitate diagnosis of aspirin-intolerant asthma and reproduce eicosanoids mediators' abnormalities described in this disease." | 7.72 | Exhaled eicosanoids following oral aspirin challenge in asthmatic patients. ( Bochenek, G; Kiełbasa, B; Sanak, M; Szczeklik, A, 2004) |
| "Aspirin-induced asthma and rhinitis (AIAR) appear to be precipitated by the inhibition of cyclo-oxygenase (COX)." | 7.71 | Aspirin-intolerant asthma: role of cyclo-oxygenase enzymes. ( Picado, C, 2002) |
| "The pathogenesis of aspirin-induced asthma (AIA) has not yet been clearly elucidated, although eicosanoid metabolites appear to play an important role." | 7.71 | Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma. ( Antczak, A; Barnes, PJ; Gorski, P; Kharitonov, S; Montuschi, P, 2002) |
| "Although many studies have assumed that the overproduction of cysteinyl- leukotrienes (cys-LTs) and an imbalance of arachidonic acid metabolism may be plausible causes for the pathogenesis of aspirin-intolerant asthma (AIA), there has been little experimental evidence to substantiate this notion in lower airways of patients with AIA." | 7.71 | A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. ( Akiyama, K; Higashi, N; Mita, H; Osame, M; Taniguchi, M, 2002) |
| "The effect of arachidonic acid or platelet agonists on LTC4 synthase activity was investigated in platelets obtained from healthy volunteers, aspirin-intolerant asthmatics or aspirin-tolerant asthmatics after in vivo treatment or in vitro pre-incubation with aspirin." | 7.71 | Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment. ( Edenius, C; Ehnhage, A; Kölbeck, KG; Lindgren, JA; Tornhamre, S, 2002) |
| "We describe the case of an aspirin-sensitive asthma patient with a history of anaphylactic reactions to nonsteroidal anti-inflammatory drugs." | 7.71 | Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma. ( Fischer, R; Harrell, K; Marks, F, 2001) |
| " In patients with aspirin-induced asthma (AIA) bronchial biopsies revealed eosinophil infiltration and a marked increase in IL-5 positive cells." | 7.71 | Serum interleukin-5 in aspirin-induced asthma. ( Mastalerz, L; Sanak, M; Szczeklik, A, 2001) |
| "Aspirin inhibits cyclooxygenase activity and modifies production of the arachidonate cascade in aspirin-induced asthma." | 7.71 | Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients. ( Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, S, 2001) |
| "Nasal polyposis occurs frequently in patients with intrinsic asthma, especially in those who are aspirin sensitive." | 7.71 | An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma. ( Darby, YC; Parikh, A; Ragab, S; Scadding, GK, 2001) |
| "The decrease in prostaglandin E(2) (PGE(2)) release due to aspirin (ASA)-induced cyclooxygenase inhibition and the increment in cysteinyl leukotriene (Cys-LT) release secondary to the removal of the inhibitory effect of PGE(2) on Cys-LT release have been suggested in the pathogenesis of aspirin-induced asthma (AIA)." | 7.71 | Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients. ( Bavbek, S; Celik, G; Melli, M; Misirligil, Z, 2001) |
| "Although there is increasing evidence of the importance of cysteinyl leukotrienes (LT) as mediators of aspirin-induced bronchoconstriction in aspirin-sensitive asthma, the cellular origin of the LT is not yet clear." | 7.71 | Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. ( Akiyama, K; Endoh, S; Kawagishi, Y; Kobayashi, M; Kudoh, M; Mita, H; Taniguchi, M, 2001) |
| "Aspirin intolerance manifests itself as two clinical symptoms, urticaria/angioedema and asthma." | 7.71 | [The study of 18 cases of aspirin urticaria at dermatology of Yodogawa Christian Hospital--on the difference between aspirin asthma and aspirin urticaria]. ( Hayashi, K; Nakamura, T; Ookami, Y; Tamaki, A, 2001) |
| "House dust mite (HDM) inhalation provocation tests were performed in HDM-sensitive asthmatic inpatients without AIA (HDM group; n = 6), and aspirin oral provocation tests were performed in AIA patients (ASA group; n = 7)." | 7.71 | Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. ( Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, SY, 2002) |
| "Aspirin intolerance is characterized by polypous rhinosinusitis, bronchial asthma and adverse reactions to aspirin." | 7.71 | [Zafirlukast in treatment of nasal polyps in patients with aspirin intolerant bronchial asthma--preliminary report]. ( Modrzyński, M; Rapiejko, P; Zawisza, E, 2002) |
| "The A to C transversion in the promoter region of the gene encoding leukotriene C4 synthase (LTC4S) is proposed to be associated with the development of aspirin-induced asthma (AIA)." | 7.71 | Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. ( Akiyama, K; Higashi, N; Kashii, T; Kawagishi, Y; Kobayashi, M; Maruyama, M; Mita, H; Oosaki, R; Taniguchi, M, 2002) |
| "In 5 to 10% of adult patients with asthma, aspirin (acetylsalicylic acid [ASA]) and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks." | 7.71 | Safety of a cyclooxygenase-2 inhibitor in patients with aspirin-sensitive asthma. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Iscar, A; Martín-García, C, 2002) |
| "Aspirin intolerant asthma (AIA) is a clinically distinct syndrome characterised by the precipitation of asthma attacks following the ingestion of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 7.71 | The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients. ( Taylor, ML; Thompson, PJ; Vally, H, 2002) |
| " It is generally accepted that in aspirin-induced asthma (AIA) the bronchospasm is provoked by inhibition of prostaglandin synthesis with overproduction of cysteinyl leukotrienes." | 7.71 | [Tolerability of Asacard--controlled-release aspirin and aspirin-induced asthma]. ( Bochenek, G; Gicquel, M; Nizankowska-Mogilnicka, E; Swierczyńska, M; Szczeklik, A; Vivet, P, 2002) |
| "Aspirin causes bronchoconstriction in aspirin-intolerant asthma (AIA) patients by triggering cysteinyl-leukotriene (cys-LT) production, probably by removing PGE2-dependent inhibition." | 7.70 | Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. ( Adamek, L; Austen, FK; Cowburn, AS; Holgate, ST; Lam, BK; Nizankowska, E; Penrose, JF; Sampson, AP; Sladek, K; Soja, J; Szczeklik, A, 1998) |
| "The pathogenic mechanism of aspirin-sensitive asthma (ASA-BA) remains to be further defined." | 7.70 | Role of circulating immune complex in aspirin-sensitive asthma. ( Nahm, DH; Park, HS, 1998) |
| "Nasal provocation tests (NPTs) with lysine-aspirin (L-ASA) have been recently introduced for assessment of aspirin-induced asthma (AIA)." | 7.70 | Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma. ( Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1998) |
| "The immunopathologic mechanism of nasal polyp in aspirin-sensitive asthma remains to be further defined." | 7.70 | Immunohistochemical characterization of cellular infiltrate in nasal polyp from aspirin-sensitive asthmatic patients. ( Nahm, DH; Park, HS; Park, K; Suh, KS; Yim, HE, 1998) |
| "Aspirin-induced asthma (AIA) is frequently accompanied by nasal polyps." | 7.70 | Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient. ( Ogata, Y; Okinaka, Y; Takahashi, M, 1999) |
| "Aspirin intolerance (AI) is characterized by polypous rhinosinusitis, bronchial asthma and adverse reactions to aspirin." | 7.70 | Arachidonic acid metabolism in nasal tissue and peripheral blood cells in aspirin intolerant asthmatics. ( Göde, U; Schäfer, D; Schmid, M; Wigand, ME, 1999) |
| "We studied the urinary excretion of 6-sulphatoxymelatonin, the major metabolite of melatonin, and the effect of different MT doses on ADP-induced platelet aggregation in vitro in 17 ASA patients, 17 patients with aspirin-tolerant asthma (ATA) and 16 healthy subjects." | 7.70 | The role of melatonin in pathogenesis of aspirin-sensitive asthma. ( Evsyukova, HV, 1999) |
| "The aspirin triad (nasal polyposis, asthma and sensitivity to aspirin) is a well-recognized clinical entity, also known as aspirin-induced asthma (AIA)." | 7.70 | Effects of sinus surgery on asthma in aspirin triad patients. ( Higuchi, Y; Kawasaki, M; Nakamura, H; Takahashi, S, 1999) |
| "Aspirin-intolerant asthma can be induced not only by acidic analgesics (including acetylsalicylic acid), which effectively inhibit cyclo-oxygenase, but also by cross-reactivity with paraben, and other chemical additives." | 7.70 | Amalgam allergy associated with exacerbation of aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Ishizaki, Y; Mikami, H; Nakagawa, H; Onuma, K; Shoji, T; Yoshida, S, 1999) |
| "Approximately 10% of patients with asthma have a distinct clinical entity in which their symptoms are exacerbated by aspirin and most other nonsteroidal anti-inflammatory agents." | 7.70 | 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. ( Baldasaro, M; Drazen, JM; Lam, BK; Penrose, JF; Stevenson, DD; Van Sambeek, R; Yandora, C; Yoshida, S; Zhao, J, 2000) |
| "Cysteinyl leukotrienes (cysLTs) are considered to be the most important mediator involved in the pathogenesis of aspirin-intolerant asthma (AIA)." | 7.70 | Effects of pranlukast, a cysteinyl leukotriene antagonist, on bronchial responsiveness to methacholine in aspirin-intolerant asthmatics treated with corticosteroids. ( Haruta, Y; Hiyama, K; Hozawa, S; Ishioka, S; Maeda, A; Tamagawa, K; Watanabe, T; Yamakido, M, 2000) |
| "Aspirin-intolerant asthma (AIA), a distinct clinical syndrome affecting about 10% of adult asthmatics, appears to be unusually dependent on cysteine leukotriene (cys-LT) overproduction by pulmonary eosinophils." | 7.70 | Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma. ( Bazan-Socha, S; Pierzchalska, M; Sanak, M; Szczeklik, A, 2000) |
| "There is a subset of patients with bronchial asthma who are susceptible to disease exacerbation upon receiving aspirin and other nonsteroidal anti-inflammatory drugs." | 7.70 | Natural history of aspirin-induced asthma. AIANE Investigators. European Network on Aspirin-Induced Asthma. ( Duplaga, M; Nizankowska, E; Szczeklik, A, 2000) |
| "Nasal provocation tests with lysine-aspirin have recently been introduced for assessment of aspirin intolerant asthma." | 7.70 | Intranasal challenge with aspirin in the diagnosis of aspirin intolerant asthma: evaluation of nasal response by acoustic rhinometry. ( Casadevall, J; Mullol, J; Picado, C; Ventura, PJ, 2000) |
| "The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease." | 7.70 | [Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000) |
| "Aspirin-induced asthma (AIA) is a clinical syndrome related to cysteinyl leukotriene overproduction in airways." | 7.70 | A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leucocytes precludes its value for aspirin sensitivity testing in asthma. ( Mastalerz, L; Pierzchalska, M; Sanak, M; Szczeklik, A; Zazula, M, 2000) |
| "Urinary excretion of leukotrienes is greater in patients with aspirin-induced asthma (AIA) than in other patients with asthma in remission, and is greater still during an aspirin-induced attack." | 7.69 | [Serum phospholipase A2 activity in patients with aspirin-induced asthma]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1995) |
| "The purpose of this study was to investigate the risk of transitional cell carcinoma among subjects with an intake of acetaminophen, aspirin, some other drugs and with some intercurrent diseases." | 7.69 | Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study. ( Gerhardsson de Verdier, M; Steineck, G; Wiholm, BE, 1995) |
| "An abnormal platelet release of oxygen-free radicals has been described in acetylsalicylic acid (aspirin)-induced asthma, a finding which might suggest the existence of an intrinsic, specific platelet abnormality of arachidonic acid metabolism in these patients." | 7.69 | In vitro release of arachidonic acid metabolites, glutathione peroxidase, and oxygen-free radicals from platelets of asthmatic patients with and without aspirin intolerance. ( Ballester, E; Gelpí, E; Mullol, J; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J; Vives-Corrons, JL, 1995) |
| "We surveyed 850 patients with bronchial asthma and investigated such clinical features as the frequency of aspirin-induced asthma and hypersensitivity to steroids in the 457 available answers." | 7.69 | [Examination on aspirin-induced asthma and hypersensitivity to steroids--a questionnaire to 850 asthma on hypersensitivity to non-steroidal anti-inflammatory drugs and hypersensitivity to steroids]. ( Adachi, M; Enomoto, T; Horikoshi, S; Ichihashi, K; Imai, T; Matsuura, T; Mita, S; Miura, Y; Okada, T, 1995) |
| "A very small number of patients with asthma show symptomatic improvement after administration of aspirin and other cyclooxygenase inhibitors." | 7.69 | Lipoxygenase inhibitor-provoked acute asthma in a patient with asthma relieved by aspirin. ( Chida, K; Hayakawa, H; Imokawa, S; Sato, A; Taniguchi, M; Toyoshima, M, 1995) |
| "This paper reports that substitution of Glucosidorum Tripterygii Totorum (GTT) for cortical hormone used to treat corticosteroid-dependent type of aspirin asthma, 60 mg, 3 times a day." | 7.69 | [Treatment of 36 corticosteroid-dependent type of aspirin asthma patients with Glucosidorum Tripterygii totorum]. ( Gao, JT, 1994) |
| "Inhalation of aerosolized lysine-aspirin (L-ASA) has been described as an alternative diagnostic method in aspirin-sensitive asthma." | 7.69 | Early and late onset asthmatic responses following lysine-aspirin inhalation in aspirin-sensitive asthmatic patients. ( Park, HS, 1995) |
| "Patients with aspirin sensitive asthma (ASA) can be desensitized to aspirin but the mechanisms by which this happens are unknown." | 7.69 | The effect of aspirin desensitization on urinary leukotriene E4 concentrations in aspirin-sensitive asthma. ( Bell, GS; Lee, TH; Nasser, SM; Patel, M, 1995) |
| "The analysis of case history, clinical, laboratory and instrumental findings, objectively characterizing the patient's condition in two alternative groups (nonaspirin and aspirin bronchial asthma) enabled the authors to create a functional diagnostic model for aspirin bronchial asthma." | 7.69 | [The diagnosis of aspirin-induced asthma by using a functional model]. ( Evsiukova, EV; Poddubskiĭ, GA; Razorenov, GI, 1995) |
| "Two female patients have been described in whom peripheral vasculitis with cold sensitivity preceded by about 5 years typical symptoms of aspirin-induced asthma." | 7.69 | Autoimmune vasculitis preceding aspirin-induced asthma. ( Bartosik, A; Dyczek, A; Milewski, M; Musiał, J; Szczeklik, A, 1995) |
| "Biochemical and immunological studies were performed to study hepatic function in 137 patients, out of whom 74 were found to have aspirin-induced bronchial asthma, 23 atopic bronchial asthma, 23 infectious allergic bronchial asthma, 17 chronic persistent hepatitis." | 7.69 | [Liver function in patients with aspirin-induced bronchial asthma]. ( Efimova, NIu; Sizykh, TP, 1994) |
| "The inflammatory cell infiltrate in bronchial biopsies of 12 aspirin-sensitive asthmatic (ASA) subjects and eight non-aspirin-sensitive (non-ASA) control subjects have been compared." | 7.69 | Inflammatory cell populations in bronchial biopsies from aspirin-sensitive asthmatic subjects. ( Barker, J; Christie, PE; Lee, TH; Nasser, SM; Pfister, R; Schmitz-Schumann, M; Sousa, AR, 1996) |
| "It is believed that aspirin (ASA) and other nonsteroidal antiinflammatory drugs elicit dysponea in ASA sensitive asthmatics by blocking the cyclooxygenase." | 7.69 | [The influence of misoprostol on post-aspirin bronchoconstriction in patients with aspirin sensitive asthma]. ( Szmidt, M; Wasiak, W, 1995) |
| "The aspirin-induced bronchoconstriction in patients with aspirin-sensitive asthma is caused by cysteinyl leukotriene release." | 7.69 | Effect of endobronchial aspirin challenge on inflammatory cells in bronchial biopsy samples from aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Nasser, S; Pfister, R; Schmitz-Schumann, M; Sousa, AR; Walls, A, 1996) |
| "Aspirin-induced asthma (AIA) should be recognized as an important types of bronchial asthma for the following reasons." | 7.69 | [Aspirin-induced asthma as an important type of bronchial asthma]. ( Sakakibara, H; Suetsugu, S, 1995) |
| "Lowered selenium (Se) status has been observed in asthma patients." | 7.69 | Selenium status is decreased in patients with intrinsic asthma. ( Gazdík, F; Ginter, E; Kadrabová, J; Kovaciková, Z; Mad'aric, A; Podivínsky, F, 1996) |
| " In contrast, the sinusitis of the aspirin triad syndrome is often fulminate, expansive, and recurrent, and complications may be more frequent." | 7.69 | Orbital complications of sinusitis in the aspirin triad syndrome. ( Massaro, BM; McFadden, EA; Toohill, RJ; Woodson, BT, 1996) |
| " CD62P and CD63) which mediate interactions between platelets and other cells may be important in the pathogenesis of aspirin-sensitive asthma." | 7.69 | Differential expression of platelet activation markers in aspirin-sensitive asthmatics and normal subjects. ( Misso, NL; Stewart, GA; Taylor, ML; Thompson, PJ, 1996) |
| "Appreciable numbers of aspirin-sensitive asthmatic patients have chronic steroid-dependent severe asthmatic symptoms." | 7.69 | Complete resolution of airway hyperresponsiveness in aspirin-sensitive asthmatic patients. ( Park, HS, 1996) |
| "In vitro cysteinyl leukotriene (cLT) release from blood leukocytes was measured in eight normal individuals (NI), nine patients with nasal polyps (NP) without aspirin intolerance, and eight patients with NP, asthma, and aspirin intolerance (AI)." | 7.69 | Increased in vitro cysteinyl leukotriene release from blood leukocytes in patients with asthma, nasal polyps, and aspirin intolerance. ( Klimek, L; Mewes, T; Riechelmann, H, 1996) |
| "We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain." | 7.69 | Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996) |
| "Aspirin-sensitive patients with asthma experience continuous inflammation of their nasal and sinus tissues, complicated by recurrent sinusitis, which frequently leads to asthma attacks." | 7.69 | Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. ( Christiansen, SC; Hankammer, MA; Mathison, DA; Simon, RA; Stevenson, DD, 1996) |
| " Upon preoperative medical evaluation, it was discovered that she was "allergic" to aspirin and suffered from stress-induced asthma." | 7.69 | Ketorolac-induced bronchospasm in an aspirin-intolerant patient. ( Bennett, CR; Chen, AH, 1994) |
| "We have shown that inhalation of lysine aspirin enhances leukotriene production in the lungs of patients with aspirin-induced asthma (AIA)." | 7.69 | Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics. ( Dworski, R; Nizankowska, E; Oates, J; Sheller, J; Sladek, K; Soja, J; Szczeklik, A, 1996) |
| "Asthmatic triad (AT) is a clinical syndrome incorporating bronchial asthma (BA), recurrent nasal and sinus polyps, intolerance of aspirin, derivatives of pirasolone and other nonsteroid antiinflammatory drugs." | 7.69 | [The in-vivo test of the inhibition of leukocyte natural migration with aspirin and analgin in the specific diagnosis of the asthmatic triad]. ( Kanchurina, NA; Poroshina, IuA; Prasolova, NI; Zemskov, VM, 1996) |
| "Aspirin-induced asthma (AIA) affects one in 10 individuals with adult-onset asthma." | 7.69 | Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes. ( Bochenek, G; Cookson, WO; Dekker, JW; Dyczek, A; Nizankowska, E; Pile, K; Schmitz-Schumann, M; Szczeklik, A, 1997) |
| "The objective of this study was to define the participation of cysteinyl leukotrienes (LTs) or thromboxane A2 in the pathogenesis of aspirin-sensitive asthma (ASA)." | 7.69 | Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. ( Akiyama, K; Kobayashi, M; Mita, H; Mizushima, Y; Oosaki, R; Shida, T, 1997) |
| "Increased numbers of eosinophils and mast cells in the bronchial mucosa are characteristic features in subjects with aspirin-sensitive asthma." | 7.69 | Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in aspirin-sensitive and non-aspirin-sensitive asthmatic airways. ( Christie, PE; Lams, BE; Lee, TH; Pfister, R; Schmitz, M; Sousa, AR, 1997) |
| "The expression of COX-1 and COX-2 isoenzymes has been studied in the bronchial mucosa of 10 normal and 18 asthmatic subjects, 11 of whom had aspirin-sensitive asthma (ASA) and seven had non-aspirin-sensitive asthma (NASA) RESULTS: There was a significant fourfold and 14-fold increase, respectively, in the epithelial and submucosal cellular expression of COX-2, but not of COX-1, in asthmatic patients." | 7.69 | Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma. ( Christie, PE; Lane, SJ; Lee, TH; Nasser, SM; Pfister, R; Schmitz-Schumann, M; Sousa, Ar, 1997) |
| "Platelet aggregation, pulmonary microcirculation and external respiration were studied against clinical appearance of the disease in 20 patients with aspirin-sensitive asthma (ASA) and 10 asthmatics without aspirin intolerance." | 7.68 | [The effect of disorders of thrombocyte functional activity on the microcirculatory status in the lungs and on external respiratory function in patients with aspirin-induced asthma]. ( Amoashiĭ, GS; Amosov, VI; Evsiukova, EV; Fedoseev, GV; Petrishchev, NN; Sinitsyna, TM, 1993) |
| "We wanted to determine whether the airway response to inhaled leukotriene C4 (LTC4) is similar to inhaled leukotriene E4 (LTE4) in aspirin-sensitive asthma and, therefore, determined airway responsiveness to histamine, LTC4 and LTE4 in seven aspirin-sensitive subjects and 13 control asthmatic subjects, who were tolerant of aspirin." | 7.68 | Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW, 1993) |
| "It is well known that nasal polyps frequently develop in patients with aspirin-induced asthma, which is thought to be a non-atopic disease." | 7.68 | [Immunohistological study of eosinophilic infiltration of nasal polyps in aspirin-induced asthma]. ( Kumagami, H; Takamura, H; Takasaki, K; Tsurumoto, H; Yoshimi, R, 1993) |
| "Inhalation challenge with lysine acetylsalicylate (L-ASA) is often used to diagnose aspirin-induced asthma." | 7.68 | Dosimeter inhalation test with lysine acetylsalicylate for the detection of aspirin-induced asthma. ( Cocco, G; Masi, C; Melillo, G; Padovano, A, 1993) |
| "To further assess this association, we studied two populations of aspirin-sensitive subjects and aspirin-tolerant subjects with asthma." | 7.68 | An analysis with sequence-specific oligonucleotide probes of the association between aspirin-induced asthma and antigens of the HLA system. ( Christie, PE; Kemeny, DM; Lee, TH; Lympany, PA; Schmitz-Schumann, M; Welsh, KI, 1993) |
| "In order to examine the hypothesis that in aspirin-induced asthma (AIA) cyclooxygenase inhibition is associated with enhanced release of leukotrienes (LTs), we measured urinary leukotriene E4 (LTE4) and 11-dehydro-thromboxane B2 (TXB2) (as a measure of cyclooxygenase production) following challenge with oral aspirin or inhaled methacholine, in 10 AIA patients." | 7.68 | Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthma. ( Sladek, K; Szczeklik, A, 1993) |
| "We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism." | 7.68 | Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993) |
| "Three groups, comprising normal subjects (n = 10), aspirin-sensitive asthmatics (ASA+; n = 10) and aspirin-insensitive asthmatics (ASA-; n = 10) were entered into a blinded, parallel group study to asses the modulating effect of aspirin (ASA; 0." | 7.68 | The effect of aspirin on mononuclear cells in aspirin-sensitive asthmatics and control subjects. ( Stewart, GA; Taylor, ML; Thompson, PJ, 1993) |
| " The in vitro effect of aspirin on platelet aggregation and ATP release induced by platelet activating factor (PAF), arachidonic acid (AA) and collagen (COL) was assessed in 10 aspirin-sensitive (ASP+) asthmatic patients and 10 normal subjects." | 7.68 | The differential effect of aspirin on human platelet activation in aspirin-sensitive asthmatics and normal subjects. ( Stewart, GA; Taylor, ML; Thompson, PJ, 1993) |
| "The etiology of aspirin-sensitive asthma is unknown, but a plausible hypothesis is that the inhibitory effect of aspirin on the cyclooxygenase enzyme increases formation of bronchoconstrictor leukotrienes via "shunting" of unmetabolized arachidonic acid into metabolism by the 5-lipoxygenase enzyme." | 7.68 | Increased excretion of leukotriene E4 during aspirin-induced asthma. ( Fitzgerald, GA; Knapp, HR; Sladek, K, 1992) |
| " We assayed urinary LTE4 in 17 normal subjects, 31 subjects with asthma without aspirin sensitivity, and 10 aspirin-sensitive subjects." | 7.68 | Urinary leukotriene E4 in bronchial asthma. ( Christie, PE; Hawksworth, RJ; Lee, TH; Smith, CM; Thien, FC, 1992) |
| " During aspirin-induced bronchospasm, release of leukotriene B4 increased significantly (45." | 7.68 | Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. ( Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL, 1992) |
| "A 40-year-old woman who had been diagnosed as having aspirin-induced asthma was admitted with stridor." | 7.68 | [A case of aspirin-induced asthma due to ketoprofen adhesive agent]. ( Goto, K; Nakahara, K; Sakai, S; Tanaka, H, 1992) |
| "Thirteen asthmatic subjects (six aspirin tolerant and seven aspirin intolerant) in a stable clinical condition and ten healthy subjects were studied." | 7.68 | Platelet kinetics in asthmatic patients with and without aspirin intolerance. ( Alonso, A; Casals, F; Picado, C; Plaza, V, 1992) |
| "We report a case of asthma that was relieved by aspirin and other cyclooxygenase inhibitors." | 7.68 | [A case of asthma relieved by aspirin--the first case in Japan and investigation of its mechanism]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1992) |
| "We have determined IgG subclass concentrations in 100 patients with aspirin-induced asthma and 80 healthy controls." | 7.68 | Altered distribution of IgG subclasses in aspirin-induced asthma: high IgG4, low IgG1. ( Milewski, M; Nizankowska, E; Roehlig, F; Schmitz-Schumann, M; Szczeklik, A; Virchow, C, 1992) |
| "Histamine release induced by platelet-activating factor (PAF) from leukocytes of aspirin-sensitive subjects with asthma was higher than that from normal control subjects, despite the similarity of anti-IgE-induced histamine release." | 7.68 | Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma. ( Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A, 1990) |
| " We experienced a case of an aspirin-sensitive asthmatic patient who developed a broncho-obstructive reaction after taking 100 mg of sodium salicylate." | 7.68 | Sodium salicylate sensitivity in an asthmatic patient with aspirin sensitivity. ( Cho, DI; Kim, JW; Lim, YS; Park, HS; Rhu, NS; Suh, JE, 1991) |
| "Upon comparison of functional activity of platelets and their response to aspirin in 20 subjects with aspirin bronchial asthma, 19 patients with non-aspirin bronchial asthma and 21 healthy controls it was found out that in aspirin asthma platelet count is elevated, their response to aggregation inductors enhances while to aspirin is abnormal, plasmic thromboxane level is reduced." | 7.68 | [Characteristics of functional activity of thrombocytes in patients with "aspirin" bronchial asthma]. ( Evsiukova, EV, 1991) |
| " In aspirin asthma following aspirin bronchial provocation NCA increases in 50% to 100% of the studied patients." | 7.68 | [Neutrophil chemotactic activity after administration of aspirin during aspirin tolerance in patients with asthma and aspirin hypersensitivity]. ( Grzegorczyk, J; Grzelewska-Rzymowska, I; Rozniecki, J; Szmidt, M, 1991) |
| "Alpha-1 antitrypsin (A-1-AT) levels were determined in 46 patients with aspirin sensitive asthma using the Eriksson method." | 7.68 | [Alpha 1-antitrypsin and its phenotype in patients with asthma and aspirin hypersensitivity]. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1991) |
| "In order to determine if aspirin sensitivity effects leukocyte reaction in aspirin sensitive asthma patients the authors studied the influence of aspirin on chemiluminescence in 12 aspirin sensitive asthmatics and 13 non-aspirin asthmatics." | 7.68 | [Effect of aspirin on FMLP (formyl-meth-leu-phe)-stimulated leukocytes in patients with asthma and hypersensitivity to aspirin]. ( Garliński, P; Grzelewska-Rzymowska, I; Rozniecki, J; Szmidt, M, 1991) |
| "Inhalation and nasal aspirin challenge has been investigated in asthma patients with co-existing rhinitis." | 7.68 | Inhalation and nasal challenge in the diagnosis of aspirin-induced asthma. ( Davies, BH; Pawlowicz, A; Williams, WR, 1991) |
| "A study is presented of 66 patients with aspirin bronchial asthma (BA) and the clinical, pathogenetical, immunological and allergological state of these patients is described." | 7.68 | [The clinico-immunological and allergological characteristics of aspirin-induced asthma]. ( Kozachuk, IA; Markov, AE, 1991) |
| "Selenium status and its relationship to lowered platelet glutathione peroxidase activity was investigated in 18 subjects with aspirin (ASA)-induced asthma and in asthmatic and non-asthmatic ASA-tolerant subjects." | 7.68 | Selenium status in relation to reduced glutathione peroxidase activity in aspirin-sensitive asthma. ( Day, JP; Miller, PF; Pearson, DJ; Suarez-Mendez, VJ, 1991) |
| "In patients with aspirin-sensitive asthma, no significant changes in plasma beta-thromboglobulin or bicyclic prostaglandin (PG) E2 were observed during aspirin challenge." | 7.68 | In vitro tests for the diagnosis of aspirin-sensitive asthma. ( Davies, BH; Pawlowicz, A; Williams, WR, 1990) |
| " Blood platelets from patients with aspirin-sensitive asthma (ASA) generated cytotoxic mediators in the presence of aspirin." | 7.68 | The abnormal in vitro response to aspirin of platelets from aspirin-sensitive asthmatics is inhibited after inhalation of nedocromil sodium but not of sodium cromoglycate. ( Capron, A; Joseph, M; Lassalle, P; Marquette, CH; Tonnel, AB; Tsicopoulos, A; Vorng, H, 1990) |
| " A 31-year-old female with intrinsic bronchial asthma and aspirin sensitivity was admitted to our hospital because of an episode of asthmatic attack." | 7.68 | [Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient]. ( Hirano, T; Kitada, O; Nakamura, H; Shiratusuki, N; Suenaga, N; Sugita, M; Uyama, O, 1990) |
| "An 11-year retrospective study was conducted to evaluate the surgical treatment of sinusitis in aspirin-triad patients." | 7.68 | Surgery for sinusitis and aspirin triad. ( Fink, JN; Kany, RJ; McFadden, EA; Toohill, RJ, 1990) |
| "One hundred seven known aspirin (ASA)-sensitive patients with rhinosinusitis-asthma were studied from 1975 to 1988." | 7.68 | Long-term effects of aspirin desensitization--treatment for aspirin-sensitive rhinosinusitis-asthma. ( Mathison, DA; Simon, RA; Stevenson, DD; Sweet, JM, 1990) |
| "In order to determine if mast cell mediators are released during aspirin challenge in aspirin-sensitive asthmatics, we measured neutrophil chemotactic activity, which has been shown to be an indicator of mast cell degranulation." | 7.67 | Identification and characterization of neutrophil chemotactic activity in aspirin-induced asthma. ( Binder, R; Braman, SS; Center, DM; Downing, ET; Glassroth, J; Hollingsworth, HM, 1984) |
| "Neutrophil chemotactic activity (NCA) following oral challenge with aspirin (ASA) was determined in ASA-intolerant asthmatic subjects, and in ASA-tolerant asthmatic and normal subjects." | 7.67 | Neutrophil chemotactic factor of anaphylaxis (NCF-A) release in aspirin-induced asthma. ( Capsoni, F; Ortolani, C; Pastorello, E; Restuccia, M; Riboldi, PS; Zanussi, C; Zocchi, M, 1984) |
| "The effects of regular aspirin ingestion after aspirin-desensitization were evaluated in 10 aspirin-intolerant asthmatic patients." | 7.67 | Effects of chronic aspirin ingestion in aspirin-intolerant asthmatic patients. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| "Three asthmatic patients with a history of bronchoconstriction after aspirin ingestion were challenged with a new analgesic, zomepirac sodium (Zomax), for determination of sensitivity to this drug." | 7.67 | Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics. ( Lumry, WR; Pleskow, WW; Simon, RA, 1984) |
| "Oral provocation tests using aspirin (n = 55), tartrazine (n = 37) and benzoate (n = 28) were performed in 55 asthmatic patients." | 7.67 | [Indications for the aspirin provocation test in the asthmatic]. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| "Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA)." | 7.67 | Aspirin tolerance induced in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1984) |
| "The role of a commonly ingested food additive, the preservative sodium metabisulfite (MBS), and aspirin (ASA), in chronic asthma has been studied in 29 children." | 7.67 | Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma. ( Mellis, CM; Towns, SJ, 1984) |
| "An aspirin- and tartrazine-sensitive asthmatic patient underwent a desensitization to the adverse effects of aspirin by oral aspirin challenges." | 7.67 | Decreased sensitivity to tartrazine after aspirin desensitization in an asthmatic patient intolerant to both aspirin and tartrazine. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| "The levels of leukotriene C4 (LTC4), leukotriene B4 (LTB4), prostaglandin E2 (PGE2), and histamine were measured in nasal lavage fluids obtained from aspirin-sensitive, desensitized aspirin-sensitive, and aspirin-insensitive asthmatics and normal volunteers before and after ingestion of aspirin." | 7.67 | Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin. ( Ferreri, NR; Howland, WC; Spiegelberg, HL; Stevenson, DD, 1988) |
| "A sulpyrin inhalation test was given to 13 patients with aspirin-induced asthma (AIA) and 8 patients with non-aspirin-induced asthma (non-AIA) to observe the changes in plasma histamine levels before and after challenges." | 7.67 | [The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients]. ( Adachi, M; Kokubu, F; Maeda, M; Okada, Y; Takahashi, T; Tanabe, Y; Tsuji, A, 1989) |
| "It is well known that nasal polyps occur at high frequency in aspirin-sensitive asthma (ASA)." | 7.67 | Etiology of nasal polyps associated with aspirin-sensitive asthma. ( Kumazawa, T; Maeda, N; Tomoda, K; Tsuji, H; Yamashita, T, 1989) |
| "Airway responsiveness to histamine and leukotriene E4 (LTE4) has been compared between five subjects with aspirin-induced asthma (AIA) and 15 asthmatic subjects without aspirin sensitivity (non-AIA)." | 7.67 | Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. ( Arm, JP; Lee, TH; O'Hickey, SP; Spur, BW, 1989) |
| " Furthermore, nedocromil sodium inhibited the abnormal response to aspirin of platelets from aspirin-sensitive asthmatics at therapeutic concentrations." | 7.67 | Nedocromil sodium inhibition of IgE-mediated activation of human mononuclear phagocytes and platelets from asthmatics. ( Capron, A; Joseph, M; Thorel, T; Tonnel, AB; Tsicopoulos, A, 1989) |
| "The paper treats long-term results of aspirin treatment of patients with aspirin-induced bronchial asthma." | 7.67 | [The late results of aspirin treatment in patients with aspirin-induced bronchial asthma]. ( Chuchalin, AG; Priputenova, ZV; Sulakvelidze, IV, 1989) |
| "Oral aspirin test was performed in 50 asthma patients." | 7.67 | [Hemosorption in the treatment of aspirin-induced bronchial asthma]. ( Didkovskiĭ, NA; Evseev, NG; Shmeleva, TK; Treskunov, VK; Zakharzhevskaia, TV, 1989) |
| "We evaluated the effects of corticosteroid pretreatment on the intensity of adverse reactions to aspirin during carefully controlled aspirin challenges in 13 aspirin-sensitive asthmatics." | 7.67 | Glucocorticosteroids attenuate aspirin-precipitated adverse reactions in aspirin-intolerant patients with asthma. ( Nizankowska, E; Szczeklik, A, 1989) |
| "Aspirin (ASA)-induced asthma is a distinct clinical syndrome in which bronchoconstrictive response to nonsteroidal anti-inflammatory drugs can be predicted on the basis of their in vitro activity as inhibitors of cyclooxygenase." | 7.67 | An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma. ( Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Nizankowska, E; Radomski, M; Szczeklik, A; Wandzilak, M, 1988) |
| " Thirty-four patients (17 with asthma and 17 with urticaria), whose case history suggested such intolerance, were challenged orally with increasing doses of seven compounds: acetylsalicylic acid, glafenine, sodium benzoate, sulfur dioxide, potassium sorbate, sodium glutamate, and tartrazine." | 7.67 | Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria. ( Frei, PC; Genton, C; Pécoud, A, 1985) |
| "Two cases of aspirin-intolerant asthma whose polymorphonuclear leukocytes demonstrated hypersensitivity to sulpyrin in vitro were reported." | 7.67 | Two cases of aspirin-intolerant asthma whose leukocytes demonstrated hypersensitivity to sulpyrin. ( Kuroume, T; Mochizuki, H; Morikawa, A; Tajima, K; Tokuyama, K, 1989) |
| "Since inhibition of cyclo-oxygenase precipitates asthmatic attacks in patients with aspirin idiosyncrasy, we have evaluated the effects of pharmacological inhibition of the next enzyme in arachidonic acid cascade, i." | 7.67 | Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma. ( Dworski, R; Gajewski, P; Nizankowska, E; Szczeklik, A, 1987) |
| " We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance." | 7.67 | Lowered glutathione-peroxidase activity in asthmatic patients with food and aspirin intolerance. ( de Wahl, K; Malmgren, R; Theorell, H; Unge, G; Zetterström, O, 1986) |
| "A hypothesis is presented which states that aspirin-induced asthma results from chronic viral infection." | 7.67 | Aspirin-induced asthma as a viral disease. ( Szczeklik, A, 1988) |
| "Platelets isolated from patients with aspirin-induced asthma (ASA patients) react abnormally in vitro to aspirin and to non-steroid anti-inflammatory drugs (NSAID), by generating cytocidal molecules, that can kill parasitic larvae and to oxygen-dependent free radicles, which may be detected by chemiluminescence, although these drugs do not have a similar effect on platelets from normal donors or allergic asthmatics." | 7.67 | [Blood platelets and asthma caused by aspirin]. ( Ameisen, JC; Capron, A; Joseph, M; Martinot, JB; Tonnel, AB, 1987) |
| "The effect of a fish oil enriched diet containing about 3 g of eicosapentaenoic acid was studied in 10 patients with aspirin intolerant asthma." | 7.67 | Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study. ( Agusti-Vidal, A; Castillo, JA; Coronas, A; Ordinas, A; Picado, C; Pujades, M; Schinca, N, 1988) |
| "Plasma aspirin esterase activity and cholinesterase activity were reduced in patients with aspirin sensitive asthma and aspirin sensitive urticaria compared to asthmatic and dermatological controls." | 7.67 | Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria. ( Asad, SI; Lessof, MH; Rawlins, MD; Williams, FM, 1987) |
| "38% of subjects who presented with aspirin (Acetyl-salicylic acid AAS)-included asthma were also found to be intolerant to metabisulphites (MBS)." | 7.67 | [Intolerance to metabisulfites in asthma induced by aspirin]. ( Bonneau, JC; Drouet, M; Ernoult, C; Le Sellin, J; Sabbah, A, 1987) |
| "We have observed in some patients that some Aspirin sensitive asthmatic present also a dyspnea after wine or foods containing sulfites ingestion." | 7.67 | [Reactions to metabisulfites in aspirin-induced asthma]. ( Bonneau, JC; Drouet, M; Le Sellin, J; Sabbah, A, 1987) |
| "Asthma, aspirin intolerance and nasal polyps form a triad of aspirin-induced asthma (AIA)." | 7.67 | Aspirin-induced asthma and nasal polyps. ( Harada, T; Irifune, M; Matsunaga, T; Nagano, T; Ogino, S; Okawachi, I, 1986) |
| "Many peripherally acting analgesic and anti-inflammatory drugs, including pyrazolone derivatives, can precipitate idiosyncratic hypersensitivity reactions in intrinsic asthmatics." | 7.67 | Pyrazolones and analgesic asthma syndrome. ( Juhl-Schaub, E; Schmitz-Schumann, M; Virchow, C, 1986) |
| "Nearly 700 specimens of polyps and sinus tissues from 12 patients with asthma and aspirin idiosyncrasy were studied with histochemical and immunofluorescent immunoglobulin techniques." | 7.67 | Histopathology and immunofluorescent immunoglobulins in asthmatics with aspirin idiosyncrasy. ( Carr, R; English, GM; Farr, R; Spector, S, 1987) |
| "Nineteen asthmatic patients, 11 with and eight without aspirin (ASA) intolerance were studied in order to test possible platelet and coagulation system involvement in the pathogenesis of aspirin-induced bronchoconstriction (AIB)." | 7.67 | Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics. ( Bednarowicz, A; Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1987) |
| "Since inhibition of cyclooxygenase precipitates asthmatic attacks in patients with aspirin idiosyncrasy, we have evaluated the effects of pharmacologic inhibition of thromboxane A2 (TXA2) synthetase, next to cyclooxygenase enzyme in arachidonic acid cascade." | 7.67 | Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma. ( Dworski, R; Gajewski, P; Nizankowska, E; Splawinska, B; Splawinski, J; Szczeklik, A, 1987) |
| "A 42-year-old man with aspirin-induced asthma also developed Prinzmetal's variant angina shortly after aspirin ingestion suggesting a possible physiologic relationship between bronchospasm and coronary spasm in aspirin-sensitive patients." | 7.67 | Is coronary arterial spasm part of the aspirin-induced asthma syndrome? ( Habbab, MA; Haft, JI; Szwed, SA, 1986) |
| "Seventy-four asthmatic patients seen in a hospital were challenged with aspirin." | 7.67 | Prevalence of aspirin intolerance in asthmatics treated in a hospital. ( Castillo, JA; Picado, C, 1986) |
| "The effect of daily aspirin (ASA) administration after "desensitisation" was studied in 16 aspirin-sensitive asthmatics." | 7.67 | Clinical efficacy of aspirin in "desensitised" aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1986) |
| "Aspirin-sensitive asthma is a common and severe disorder characterized by asthmatic attacks after oral ingestion of cyclooxygenase inhibiting drugs." | 7.67 | [Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences]. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985) |
| "The pathogenesis of aspirin-sensitive asthma remains unknown." | 7.67 | Aspirin-sensitive asthma: abnormal platelet response to drugs inducing asthmatic attacks. Diagnostic and physiopathological implications. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Maclouf, J; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985) |
| "This study attempted to determine whether or not nasal and sinus surgery had a beneficial or deleterious effect upon the asthma of patients with nasal polyps and aspirin idiosyncrasy." | 7.67 | Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy. ( English, GM, 1986) |
| "In a study of the incidence of respiratory reaction to tartrazine, challenge tests were made with doses of 5, 25, 50, 100 and 200 mg of tartrazine and with a placebo, on forty-seven patients with asthma associated with intolerance to analgesics (ASA-Triad)." | 7.67 | Challenge tests with tartrazine in patients with asthma associated with intolerance to analgesics (ASA-Triad). A comparative study with placebo. ( Basomba, A; Campos, A; Garcia Villalmanzo, I; Morales, MC; Pelaez, A, 1985) |
| "In a group of aspirin-sensitive asthmatics we studied skin weal and flare responses to intradermal injections of compound 48/80 and histamine during oral aspirin (ASA) provocation and after ASA "desensitisation"." | 7.67 | The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
| "Twenty seven aspirin sensitive asthmatic patients were studied to determine the relationship between non-specific bronchial responsiveness to inhaled histamine and the degree of sensitivity to aspirin (aspirin threshold dose)." | 7.67 | Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
| " As the lipoxygenase pathway is the only operant metabolic system available for arachidonic acid in the presence of aspirin and non-steroidal anti-inflammatory drugs--and as the nonsteroidal anti-inflammatory drugs themselves stimulate mucus production--it is possible that the mechanism responsible for mucus release in aspirin-sensitive asthmatics is the formation of these lipoxygenase products." | 7.66 | Possible mechanisms underlying mucus secretion in aspirin-sensitive asthma. ( Kaliner, M; Marom, Z, 1983) |
| "Activation of complement was sought by two independent assay methods, total hemolytic complement (CH50) and C4 activation by rocket immunoelectrophoresis for C4d and C4 in plasma samples obtained from 16 aspirin-sensitive asthmatic patients and four control subjects during provocative oral aspirin challenges." | 7.66 | The absence of detectable complement activation in aspirin-sensitive asthmatic patients during aspirin challenge. ( Chenoweth, DE; Curd, JG; Pleskow, WW; Simon, RA; Stevenson, DD, 1983) |
| "In order to determine the types of respiratory responses observed during aspirin-induced reactions, 50 consecutive asthmatic patients with a history of aspirin sensitivity underwent prospective oral aspirin challenges between 1979 and 1981." | 7.66 | Aspirin-sensitive rhinosinusitis/asthma: spectrum of adverse reactions to aspirin. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1983) |
| "To determine whether the different modes of action of aspirin and acetaminophen are associated with different incidences of bronchoconstriction, and whether there is cross-reactivity in terms of intolerance, selected asthmatics were challenged with both analgesics." | 7.66 | Acetaminophen and aspirin challenges in subgroups of asthmatics. ( Falliers, CJ, 1983) |
| "Thirty aspirin-sensitive asthmatic patients underwent incremental, oral aspirin challenge until a "positive reaction" (delta FEV1 greater than or equal to 25%) occurred." | 7.66 | Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1982) |
| "Aspirin-sensitive asthma is not well documented in children." | 7.66 | Aspirin-induced asthma in children. ( Collins-Williams, C; Tan, Y, 1982) |
| "This study undertook to determine the usefulness of tartrazine and benzoate challenge and dietary avoidance in the management of patients with chronic asthma." | 7.66 | Tartrazine and benzoate challenge and dietary avoidance in chronic asthma. ( Broder, I; Tarlo, SM, 1982) |
| " 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man." | 7.66 | Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981) |
| "Eleven patients with intrinsic asthma and aspirin sensitivity were challenged with intravenous hydrocortisone sodium succinate (Solu-Cortef; the Upjohn Co." | 7.66 | Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. ( Dajani, BM; Hamzeh, YS; Shubair, KS; Sliman, NA, 1981) |
| "Two aspirin-sensitive asthmatic patients underwent oral aspirin challenges for investigative purposes." | 7.66 | Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. ( Mathison, DA; Simon, RA; Stevenson, DD, 1980) |
| "Since it has been suggested that aspirin-induced asthma is due to inhibition of prostaglandin (PG) biosynthesis, the present investigation was undertaken to determine whether tartrazine would display a similar profile." | 7.66 | Is tartrazine-induced asthma related to inhibition of prostaglandin biosynthesis? ( Bessot, JC; Pauli, G; Vargaftig, BB, 1980) |
| "An H1-receptor blocking antihistamine, clemastine, taken before aspirin gave complete or partial protection against flushing, rhinorrhea, cough, and headache in ten asthmatic patients with idiosyncrasy to aspirin." | 7.66 | Inhibition of idiosyncratic reactions to aspirin in asthmatic patients by clemastine. ( Serwonska, M; Szczeklik, A, 1979) |
| "In an attempt to elucidate the mechanisms involved in analgesic-induced asthma, I performed bronchial and intravenous challenge tests with indomethacin in 5 aspirin-sensitive asthmatics." | 7.66 | Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics. ( Martelli, NA, 1979) |
| "Nasal polypectomy is safe in patients with asthma and intolerance to aspirin." | 7.66 | Nasal polypectomy in patients with asthma and sensitivity to aspirin. ( Brown, BL; Harner, SG; Van Dellen, RG, 1979) |
| "A case report is presented demonstrating the beneficial beta2 stimulating effect of halothane in a patient with status asthmaticus unresponsive to adequate conventional therapy." | 7.66 | Halothane for status asthmaticus in the intensive care unit--a case report. ( Colaco, CM; Crago, RR; Weisbert, A, 1978) |
| "A case of an adverse reaction occurring in a 53-year-old, aspirin-sensitive asthmatic male with nasal polyps following administration of a 400-mg ibuprofen tablet is reported." | 7.66 | Cross-reactivity between aspirin and ibuprofen in an asthmatic--a case report. ( Merritt, GJ; Selle, RI, 1978) |
| "The efficacy of triamcinolone acetonide aerosol in the management of asthma in six patients with aspirin hypersensitivity was evaluated during a one-year trial." | 7.65 | Triamcinolone aerosol. Treatment of aspirin-hypersensitive asthmatic patients. ( Bone, RC; Kerby, GR; Pingleton, WW; Ruth, WE, 1977) |
| "Eighteen patients with asthma and aspirin hypersensitivity have been challenged with increasing doses of aspirin, fenoprofen, ibuprofen, and dextropropoxyphene." | 7.65 | Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A; Zmuda, A, 1976) |
| "The effect of aerosolized prostaglandin F2alpha (PGF2alpha) on specific airway resistance (SRaw) has been measured in patients with common (n = 10) or aspirin-sensitive asthma (n = 5)." | 7.65 | Bronchial response to inhaled prostaglandin F2alpha in patients with common or aspirin-sensitive asthma. ( Charpin, J; Gayrard, P; Grimaud, C; Orehek, J, 1977) |
| "Bronchial reactivity to prostaglandins F2alpha (PGF2alpha), E2 (PGE2) and histamine has been studied in 27 patients with aspirin-sensitive asthma and in 28 asthmatics without this sensitivity." | 7.65 | Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma. ( Nizankowska, E; Nizankowski, R; Szczeklik, A, 1977) |
| "Levels of circulating IgE, total haemolytic complement, and components C4 and C3 were measured in 16 asthmatics with aspirin idiosyncrasy and in control subjects." | 7.65 | Complement components and IgE in patients with asthma and aspirin idiosyncrasy. ( Delaney, JC; Kay, AB, 1976) |
| "Under carefully controlled conditions, seven aspirin-intolerant asthmatic patients were challenged with oral aspirin and experienced respiratory tract reactions with a decline in forced expiratory volume in 1 sec (FEV1) ranging from 26 to 64%." | 7.65 | Oral aspirin challenges in asthmatic patients: a study of plasma histamine. ( Arroyave, CM; Bhat, KN; Stevenson, DD; Tan, EM, 1976) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 7.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| "The lysine-ASA challenge was highly reproducible (geometric mean for group PD20 being identical for the open prestudy and the placebo session), and was associated with a post-challenge increase in urinary LTE4." | 6.67 | The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics. ( Blomqvist, H; Dahlén, B; Dahlén, SE; Kumlin, M; Larsson, C; Margolskee, DJ; Williams, VC; Zetterström, O, 1993) |
| "Sinusitis is very common, so it is important to understand its pathophysiology, diagnosis, and medical and surgical treatments." | 6.43 | Sinusitis: allergies, antibiotics, aspirin, asthma. ( Radojicic, C, 2006) |
| "Bronchial asthma is not a homogenous disease." | 6.41 | Diagnosis, prevention and treatment of aspirin-induced asthma and rhinitis. ( Bánska, K; Bochenek, G; Nizankowska, E; Szabó, Z; Szczeklik, A, 2002) |
| "Aspirin was discovered by Gerhardt in 1853." | 6.40 | [Asthma and aspirin]. ( Sonneville, A, 1998) |
| "Aspirin was discovered by Gerhardt in 1853." | 6.40 | Current synthetic notions on aspirin induced asthma. ( Sonneville, A, 1999) |
| "Treatment of the nasal polyps has been shown to improve the patients' asthma." | 6.38 | Nasal polyps, bronchial asthma and aspirin sensitivity. ( Hawke, M; Jeney, E; Probst, L; Stoney, P, 1992) |
| "Some particular cases of bronchial asthma are improved by acetylsalicylic acid." | 6.38 | [Asthma relieved by aspirin]. ( Frans, A; Garin, P, 1989) |
| "Aspirin sensitivity has a highly significant association with AFRS." | 5.48 | Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study. ( Ahmed, S; Almeyda, R; Anari, S; Carrie, S; Cathcart, R; Clark, A; Coombes, E; Erskine, S; Farboud, A; Hobson, J; Hopkins, C; Jervis, P; Kara, N; Khalil, H; Kumar, N; Mansell, N; Panesaar, J; Philpott, C; Philpott, CM; Prinsley, P; Ray, J; Robertson, A; Salam, M; Sunkaraneni, S; Sunkaraneni, V; Wilson, A; Woods, J, 2018) |
| "Aspirin-exacerbated respiratory disease (AERD) is characterized by abnormal arachidonic acid metabolism leading to chronic rhinosinusitis with nasal polyposis (CRSwNP), asthma, and upper and/or lower respiratory symptoms after ingestion of cyclooxygenase-1 inhibiting nonsteroidal antiinflammatory drugs." | 5.41 | Aspirin-Exacerbated Respiratory Disease and the Unified Airway: A Contemporary Review. ( Choby, G; Divekar, RD; Hagan, JB; O'Brien, EK; Pinheiro-Neto, CD; Stokken, JK; Walters, BK; Willson, TJ, 2023) |
| "Aspirin exacerbated respiratory disease (AERD) is a condition caused by increased bronchoconstriction in people with asthma after taking aspirin or another NSAID." | 5.41 | Aspirin-Exacerbated Respiratory Disease Polymorphisms; a review study. ( Abyaneh, FA; Darabi, B; Ebrahimi, M; Fathollahpour, A; Kalmarzi, RN; Kooti, W, 2023) |
| "Aspirin-exacerbated respiratory disease (AERD) is a chronic respiratory condition characterized by severe chronic rhinosinusitis with nasal polyps (CRSwNP), eosinophilic asthma, and respiratory reactions to cyclooxygenase inhibitors." | 5.41 | Aspirin-exacerbated respiratory disease: Updates in the era of biologics. ( Buchheit, KM; Mullur, J, 2023) |
| "Aspirin sensitivity was established previously in all six patients during a prior ASA oral challenge." | 5.31 | Lack of effect of the 5-lipoxygenase inhibitor zileuton in blocking oral aspirin challenges in aspirin-sensitive asthmatics. ( Daffern, PJ; Pauls, JD; Simon, RA; Stevenson, DD, 2000) |
| "Montelukast pretreatment was generally not effective in altering upper airway reactions and only partly effective in altering lower airway reactions." | 5.31 | Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics. ( Christiansen, SC; Mathison, DA; Simon, RA; Stevenson, DD, 2000) |
| "These post hoc analyses of pooled data from 2 BREATH phase 3 clinical trials, studies 1 and 2 (NCT01287039 and NCT01285323), examined asthma-related outcomes in patients with comorbid, self-reported CRSwNP with and without aspirin sensitivity." | 5.30 | Effects of Reslizumab on Asthma Outcomes in a Subgroup of Eosinophilic Asthma Patients with Self-Reported Chronic Rhinosinusitis with Nasal Polyps. ( Bardin, P; Bateman, ED; Garin, M; Germinaro, M; Hoyte, FCL; Katial, RK; Korn, S; McDonald, M; Weinstein, SF, 2019) |
| "Flurbiprofen (Ansaid) is a newly released nonsteroidal antiinflammatory drug (NSAID) that is a potent inhibitor of prostaglandin synthesis." | 5.28 | Flurbiprofen (Ansaid) cross-sensitivity in an aspirin-sensitive asthmatic patient. ( Bosso, JV; Creighton, D; Stevenson, DD, 1992) |
| "The inhalation challenge with lysine-aspirin (L-ASA) using the dosimeter method allows the construction of a dose-response curve and the quantitative estimation of airway responsiveness to the drug." | 5.28 | Aspirin-induced asthma and bronchial hyperresponsiveness. ( Cocco, G; Masi, C; Melillo, E; Melillo, G; Padovano, A, 1991) |
| "Tissue eosinophilia is regulated by chemical attractants and activating substances of various origins and plays a major part in the chronic inflammatory state." | 5.28 | Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin. ( Guyot, JL; Hsieh, V; Maria, Y; Moneret-Vautrin, DA; Mouton, C; Wayoff, M, 1990) |
| "Fourteen patients with mild intermittent asthma and 2 patients with aspirin-exacerbated respiratory disease received 20 mg of montelukast twice daily and placebo for 5 to 7 days in a randomized, double-blind, crossover study (NCT01841164)." | 5.27 | Leukotriene E ( Bood, J; Dahlén, B; Dahlén, SE; Davis, A; Gomez, C; Gyllfors, P; Kolmert, J; Lantz, AS; Lazarinis, N; Wheelock, CE, 2018) |
| "of our patients with bronchial asthma." | 5.27 | [Inhalation provocation test with lysine acetylsalicylic acid (Aspisol)--a useful method for the diagnosis of analgesic asthma]. ( Kirsten, D; Meister, W; Treutler, D, 1984) |
| "Maxillofacial pain is often managed by the use of mild analgesics, such as acetylsalicylic acid and nonsteroidal anti-inflammatory agents." | 5.27 | Aspirin-intolerance syndrome. Report of a case. ( Fridrich, HH; Fridrich, KL; Zach, GA, 1986) |
| "Nasal polyps were twice as common in men as women, though a woman with nasal polyps was twice as likely to have asthma as a man." | 5.26 | Nasal polyps, nasal polypectomy, asthma, and aspirin sensitivity. Their association in 445 cases of nasal polyps. ( Moloney, JR, 1977) |
| " In the uncommon occurrence of asthma and diabetes in the same patient, insulin dosage should be considered as a factor in all such asthmatics who do not respond well to conventional therapy." | 5.26 | Diabetes mellitus and insulin in an aspirin sensitive asthmatic. ( Caplin, I, 1976) |
| "Aspirin exacerbated respiratory disease (AERD) is comprised of aspirin/acetylsalicylic acid (ASA) sensitivity, bronchial asthma, and nasal polyposis." | 5.20 | Treatment of aspirin exacerbated respiratory disease with a low salicylate diet: a pilot crossover study. ( Au, M; Gupta, MK; Hoffbauer, S; Nayan, S; Sommer, DD; Sowerby, LJ, 2015) |
| "Numerous open trials have demonstrated the beneficial clinical effects of aspirin desensitization (AD) in patients with aspirin-induced asthma (AIA)." | 5.19 | Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study. ( Bochenek, G; Ćmiel, A; Gielicz, A; Niżankowska-Mogilnicka, E; Plutecka, H; Sanak, M; Stręk, P; Świerczyńska-Krępa, M; Szczeklik, A, 2014) |
| "The historic triad of nasal polyposis, asthma and intolerance to aspirin and related chemicals, recently designated as Samter's syndrome, is an inflammatory condition of unknown pathogenesis." | 5.17 | Effects of omalizumab on eosinophil cationic peptide, 25-hydroxyvitamin-D, IL-1β and sCD200 in cases of Samter's syndrome: 36 months follow-up. ( Gumuslu, S; Strauss, LG; Uçar, S; Yalcin, AD, 2013) |
| "Twenty-one adult patients with asthma, chronic polypoid sinusitis, and a convincing history of acute respiratory reaction to the ingestion of aspirin or nonsteroidal anti-inflammatory drugs were selected." | 5.14 | The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseases. ( Alam, R; Katial, RK; Leung, R; Prasertsuntarasai, T; Strand, M; Zheng, W, 2010) |
| "The daily dose of aspirin in desensitization in aspirin-sensitive asthmatics with nasal polyps is still a matter of debate." | 5.13 | Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily. ( Deutschle, T; Keck, T; Polzehl, D; Riechelmann, H; Rozsasi, A; Smith, E; Wiesmiller, K, 2008) |
| "A special regulatory role for prostaglandin E2 has been postulated in aspirin-induced asthma." | 5.13 | Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity. ( Cmiel, A; Gawlewicz-Mroczka, A; Gielicz, A; Mastalerz, L; Sanak, M; Szczeklik, A, 2008) |
| "Aspirin can cause bronchoconstriction in some asthmatic patients through increased production of proinflammatory mediators, particularly leukotrienes." | 5.13 | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. ( Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A, 2008) |
| "Randomised data in men show a small but significant reduction in the risk of adult-onset asthma among those given aspirin." | 5.13 | Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study. ( Barr, RG; Buring, JE; Gaziano, JM; Kurth, T, 2008) |
| "Aspirin (ASA) and several other nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclo-oxygenase (COX) enzyme both isoforms 1 and 2, and can precipitate asthmatic attacks in aspirin-induced asthmatics." | 5.12 | Nasal and bronchial tolerability of Rofecoxib in patients with aspirin induced asthma. ( Dal Negro, R; Guerriero, M; Micheletto, C; Tognella, S, 2006) |
| "To study the safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, and to determine whether it cross-reacts with asthma in patients with aspirin-exacerbated respiratory disease (AERD)." | 5.12 | Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory disease. ( Ahmed, I; El Gaafary, M; El Miedany, Y; Youssef, S, 2006) |
| "The anti-inflammatory actions of acetylsalicylic acid (ASA)/non-steroidal anti-inflammatory drugs (NSAIDs) are thought to be due to inhibition of COX-2, whereas the side effects such as gastric damage and aspirin-induced asthma are mediated through inhibition of COX-1." | 5.12 | Safety of meloxicam in aspirin-hypersensitive patients with asthma and/or nasal polyps. A challenge-proven study. ( Bavbek, S; Dursun, AB; Dursun, E; Eryilmaz, A; Misirligil, Z, 2007) |
| "To evaluate whether controller medications, particularly leukotriene modifier drugs, taken during oral aspirin challenges can reduce the risk of severe asthmatic responses." | 5.12 | Effect of leukotriene modifier drugs on the safety of oral aspirin challenges. ( Ludington, E; Mehra, P; Simon, RA; Stevenson, DD; White, A, 2006) |
| "Nasal polyposis associated with aspirin-intolerant asthma tends to be difficult to control, with frequent recurrences." | 5.12 | Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma. ( Darby, Y; Ogata, N; Scadding, G, 2007) |
| "Aspirin-induced asthma (AIA) is a clinical syndrome characterized by acute airway reaction to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS)." | 5.11 | Montelukast 10 mg improves nasal function and nasal response to aspirin in ASA-sensitive asthmatics: a controlled study vs placebo. ( Dal Negro, RW; Micheletto, C; Pomari, C; Tognella, S; Trevisan, F; Visconti, M, 2004) |
| "Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can precipitate adverse reactions in two apparently different clinical conditions: bronchial asthma and chronic idiopathic urticaria (CIU)." | 5.11 | Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma. ( Mastalerz, L; Sanak, M; Setkowicz, M; Szczeklik, A, 2004) |
| " Three subjects with multiple-drug induced urticaria complained of a generalized reaction after challenge (Two due to celecoxib and one due to meloxicam)." | 5.11 | Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients. ( Antonicelli, L; Bilò, MB; Bonadonna, P; Crivellaro, MA; Dama, AR; Schiappoli, M; Senna, G, 2004) |
| "Aspirin-induced asthma (AIA) is associated with increased production of cysteinyl leukotrienes (CysLT)." | 5.11 | Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma. ( Haggart, K; Lee, DK; Lipworth, BJ; Robb, FM, 2004) |
| "Aspirin-exacerbated respiratory disease (AERD) is characterized by progressive sinusitis, nasal polyposis, and asthma that begins and continues in the absence of exposure to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs)." | 5.11 | Safety of high-dose rofecoxib in patients with aspirin-exacerbated respiratory disease. ( Simon, RA; Stevenson, DD; Woessner, KM, 2004) |
| "The exact mechanism of aspirin-induced asthma is not clear." | 5.11 | Tacrolimus reduces urinary excretion of leukotriene E(4) and inhibits aspirin-induced asthma to threshold dose of aspirin. ( Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S, 2004) |
| "In patients with aspirin-exacerbated respiratory disease (AERD), pretreatment with asthma controller medications (leukotriene modifiers, inhaled or systemic corticosteroids, and salmeterol) partially modifies the severity of aspirin-induced asthmatic reactions." | 5.11 | Failure of tacrolimus to prevent aspirin-induced respiratory reactions in patients with aspirin-exacerbated respiratory disease. ( Gupta, S; Mehra, PK; Simon, RA; Stevenson, DD; White, AA; Woessner, KM, 2005) |
| "To determine whether celecoxib, a selective cyclooxygenase 2 (COX-2) inhibitor, cross-reacts in patients with aspirin-exacerbated respiratory disease (AERD) with asthma." | 5.10 | The safety of celecoxib in patients with aspirin-sensitive asthma. ( Simon, RA; Stevenson, DD; Woessner, KM, 2002) |
| "Patients with asthma who have aspirin sensitivity have greater cysteinyl leukotriene production and greater airway hyperresponsiveness to the effects of inhaled cysteinyl leukotrienes than their aspirin-tolerant counterparts." | 5.10 | Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis. ( Corrigan, CJ; Lee, TH; Parikh, A; Scadding, G; Sousa, AR, 2002) |
| "We compared the clinical response to montelukast in two well-matched groups of patients with mild asthma: 26 aspirin-intolerant asthmatics (AIAs) and 33 aspirin-tolerant asthmatics (ATAs)." | 5.10 | Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist. ( Bazan-Socha, S; Bestynska-Krypel, A; Cmiel, A; Mastalerz, L; Mejza, F; Nizankowska, E; Pierzchalska, M; Sanak, M; Szczeklik, A, 2002) |
| " Changes in nasal and asthma symptoms, combined with changes in oral prednisone, were recorded daily during 4 weeks before and after desensitization." | 5.10 | Early effects of aspirin desensitization treatment in asthmatic patients with aspirin-exacerbated respiratory disease. ( Berges-Gimeno, MP; Simon, RA; Stevenson, DD, 2003) |
| "Subjects with aspirin-intolerant asthma (AIA) respond with bronchoconstriction and extrapulmonary adverse reactions to conventional nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit the cyclooxygenase (COX) step in the biosynthesis of prostaglandins." | 5.10 | Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. ( Bochenek, G; Dahlén, B; Dahlén, SE; Drupka, D; Gyllfors, P; Isakson, PC; Kumlin, M; Lefkowith, JB; Mejza, F; Murray, JJ; Nizankowska, E; Overholt, J; Sheller, J; Szczeklik, A, 2003) |
| "The aim of this study was to assess the efficacy of leucotrien- antagonists in aspirin-intolerant asthma (AIA)." | 5.10 | [The effectiveness of leukotriene antagonists in the treatment of aspirin-intolerant asthmatic patients]. ( Arvin-Berod, C; Paganin, F; Poubeau, P; Yvin, JL, 2003) |
| "Aspirin-induced asthma/rhinitis (AIAR) is characterized by the altered metabolism of leukotrienes and proinflammatory prostaglandins." | 5.10 | Nasal versus bronchial and nasal response to oral aspirin challenge: Clinical and biochemical differences between patients with aspirin-induced asthma/rhinitis. ( Gielicz, A; Nizankowska-Mogilnicka, E; Swierczynska, M; Szczeklik, A; Zarychta, J, 2003) |
| "We have aimed to determine the sensitivity and specificity of a simpler technique with less risk than oral provocation to diagnose aspirin-induced asthma (AIA)." | 5.10 | Nasal provocation test (NPT) with aspirin: a sensitive and safe method to diagnose aspirin-induced asthma (AIA). ( Alonso-Llamazares, A; Cimarra-Alvarez, M; Domínguez-Ortega, J; Martinez-Cócera, C; Mesa del Castillo, M; Robledo-Echarren, T, 2002) |
| "Little is known about the anti-asthmatic effects of powerful anti-inflammatory agents such as aspirin-like drugs." | 5.09 | Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1999) |
| "The underlying mechanisms of bronchoconstriction in aspirin-intolerant asthmatics (AIAs) are still unknown, but the hypothesis of an altered metabolism of arachidonic acid is generally accepted." | 5.09 | Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics. ( Baenkler, HW; Göde, UC; Schäfer, D; Schmid, M, 1999) |
| "This study was designed to investigate the protective effect of roxithromycin on airway responsiveness to the sulpyrine provocation test and to investigate whether this protective activity is associated with a reduction in aspirin-induced excretion of urinary leucotriene E4 (u-LTE4), a marker of cysteinyl leucotriene overproduction that participates in the pathogenesis of aspirin-intolerant asthma." | 5.09 | Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Nakagawa, H; Sakamoto, H; Shoji, T; Yoshida, S, 1999) |
| "Prostaglandins of the E series and misoprostol (a stable analogue of prostaglandin E(1)) prevent bronchoconstriction following aspirin ingestion or inhalation in subjects with aspirin sensitive asthma." | 5.09 | A six week double blind, placebo controlled, crossover study of the effect of misoprostol in the treatment of aspirin sensitive asthma. ( Szmidt, M; Wasiak, W, 1999) |
| "Bradykinin (BK) is a mediator of inflammation in asthma with potent bronchoconstrictor actions." | 5.09 | Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma. ( Barnes, PJ; Chung, KF; Kharitonov, SA; Sapienza, MM, 1999) |
| "Albeit its exact pathogenesis is still ambiguous; aspirin-intolerant asthma is one of several types of asthma for which antileukotriene therapy is useful, because it is widely accepted that bronchial over-production of leukotrienes may be involved in its pathogenesis." | 5.09 | Efficacy of leukotriene receptor antagonist in bronchial hyperresponsiveness and hypersensitivity to analgesic in aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Ishizaki, Y; Nakabayashi, M; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Yoshida, S, 2000) |
| "In 35 asthmatic patients with acetylsalicylic acid (aspirin; ASA) intolerance (AIA) and 15 asthmatics tolerating ASA well, the authors compared the diagnostic value of the placebo-controlled oral ASA versus inhaled L-lysine (L) ASA challenges." | 5.09 | Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma. ( Bestyńska-Krypel, A; Cmiel, A; Nizankowska, E; Szczeklik, A, 2000) |
| "In a subset of patients with asthma, aspirin and several other non-steroidal anti-inflammatory drugs (NSAID) that inhibit simultaneously cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) precipitate dangerous asthmatic attacks." | 5.09 | Safety of a specific COX-2 inhibitor in aspirin-induced asthma. ( Bochenek, G; Mejza, F; Nagraba, K; Nizankowska, E; Swierczynska, M; Szczeklik, A, 2001) |
| "The goal of this study was to determine whether rofecoxib cross-reacts in aspirin-sensitive patients with asthma." | 5.09 | Lack of cross-reactivity between rofecoxib and aspirin in aspirin-sensitive patients with asthma. ( Simon, RA; Stevenson, DD, 2001) |
| "Although administration of cromolyn sodium is one of the most useful drugs for the treatment of aspirin-intolerant asthma (AIA), both its pharmacologic mechanism of action and association with the pathogenesis remain obscure." | 5.09 | Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Ishizaki, Y; Nakabayashi, M; Nakagawa, H; Shoji, T; Yoshida, S, 2001) |
| "Nine patients with moderate and severe aspirin bronchial asthma (ABA) received epifamine (a course dose 400 mg) in addition to continuous antiasthmatic therapy." | 5.09 | [Epifamine efficacy in aspirin bronchial asthma]. ( Bondarenko, VL; Evsiukova, EV; Khavinson, VKh; Sinitsina, TM; Totoliam, AA; Trofimov, VI, 2001) |
| "Cross-sensitivity between aspirin and acetaminophen in aspirin-sensitive asthmatic patients has been reported with frequencies ranging from 0% to 29%." | 5.08 | Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects. ( Christiansen, SC; Mathison, DA; Schrank, PJ; Settipane, RA; Simon, RA; Stevenson, DD, 1995) |
| "We conclude that aspirin-sensitive patients with asthma are not preferentially sensitive to hydrocortisone and that hydrocortisone sodium succinate does not cross-react or cross-desensitize with aspirin." | 5.08 | Hydrocortisone sodium succinate does not cross-react with aspirin in aspirin-sensitive patients with asthma. ( Feigenbaum, BA; Simon, RA; Stevenson, DD, 1995) |
| "Intravenous (n = 21) and inhalational maintenance anaesthesia (n = 21) were compared by random allocation in patients with the aspirin intolerance syndrome undergoing endoscopic nasal procedures." | 5.08 | A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome. ( Novak-Jankovic, V; Paver-Erzen, V; Podboj, J, 1995) |
| "Inhaled lysine acetylsalicylate and furosemide exert a mutually potentiating protective activity on experimentally induced bronchoconstriction in asthma." | 5.08 | Steroid-sparing effect of inhaled lysine acetylsalicylate and furosemide in high-dose beclomethasone-dependent asthma. ( Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1995) |
| "We performed a double-blind, two-phase study on protective and bronchodilator effects of prostaglandins E2 and E1 (PGE2, PGE1) and salbutamol in patients with aspirin-induced asthma (AIA)." | 5.08 | Protective and bronchodilator effects of prostaglandin E and salbutamol in aspirin-induced asthma. ( Cmiel, A; Mastalerz, L; Nizankowska, E; Szczeklik, A, 1996) |
| "Bronchial overproduction of leukotrienes and inhibition of prostaglandin synthesis are involved in the pathogenesis of aspirin-induced asthma." | 5.08 | Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma. ( Armetti, L; Bianco, S; Folco, GC; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sala, A; Sestini, P; Vaghi, A, 1996) |
| " Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 5.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
| "When administered by inhalation, histamine provokes dose-related bronchoconstriction in asthmatic subjects mainly by a direct activation of histamine H1-receptors on airway smooth muscle." | 5.08 | Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma. ( Crimi, N; Magrì, S; Mastruzzo, C; Mistretta, A; Paolino, G; Polosa, R; Prosperini, G, 1996) |
| " In study 1, 15 non-aspirin sensitive patients with mild asthma attended on four occasions and inhaled 5 ml of lysine aspirin (L-aspirin) 900 mg, indomethacin 50 mg, sodium salicylate 800 mg, or saline 20 minutes before an inhaled MBS challenge." | 5.08 | Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma. ( Knox, A; Pavord, I; Tattersfield, A; Wang, M; Wisniewski, A, 1996) |
| "The protective activity of nedocromil sodium and of sodium cromoglycate against aspirin-induced asthma has never been investigated in controlled studies." | 5.08 | Attenuation of aspirin-induced bronchoconstriction by sodium cromoglycate and nedocromil sodium. ( Bianco, S; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1997) |
| "When administered by inhalation, bradykinin provokes dose-related bronchoconstriction in asthmatic subjects by a mechanism believed to involve activation of sensory nerve endings." | 5.08 | Activity of inhaled lysine acetylsalicylate (L-ASA) on bradykinin-induced bronchoconstriction in asthmatics: evidence of contribution of prostaglandins. ( Crimi, N; Magrì, S; Milazzo, VL; Pagano, C; Paolino, G; Polosa, R; Prosperini, G; Santonocito, G, 1997) |
| "We performed a double-blind, crossover, placebo-controlled study on the effect of fluticasone propionate (FP) treatment on chronic eosinophilic rhinosinusitis in 15 patients with aspirin-induced asthma (AIA)." | 5.08 | Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma. ( Duplaga, M; Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1997) |
| "Inhalation of cromolyn sodium protects against sulpyrine-induced bronchoconstriction and prevents urinary leukotriene E4 (u-LTE4) excretion in aspirin-induced asthma." | 5.08 | Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthma. ( Amayasu, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Tajima, T; Yoshida, S, 1998) |
| "From bronchoprovocation studies and investigations of the acute effects of drugs that inhibit leukotrienes (LT), the hypothesis has emerged that leukotrienes are important mediators of airway obstruction and other symptoms in aspirin-intolerant asthma (AIA)." | 5.08 | Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. ( Bochenek, G; Boodhoo, TI; Dahlén, B; Dahlén, SE; Dubé, LM; Kumlin, M; Mastalerz, L; Nizankowska, E; Pinis, G; Swanson, LJ; Szczeklik, A; Wright, S; Zetterström, O, 1998) |
| "We determined the effect of a long acting beta2-agonist, salmeterol, on aspirin-induced asthma (AIA) attacks and urinary release of eicosanoids in a double-blind, placebo-controlled, crossover study in 10 asthmatics sensitive to aspirin." | 5.08 | Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism. ( Cmiel, A; Dworski, R; Mastalerz, L; Nizankowska, E; Oates, JA; Prokop, A; Sheller, JR; Szczeklik, A, 1998) |
| "This study was designed to investigate the protective effect of cromolyn sodium on airway sensitivity to sulpyrine, and bronchial responsiveness to methacholine, and to investigate whether this protective activity is associated with reduction in aspirin-induced excretion of urinary leukotriene E4 (u-LTE4), a marker of the cysteinyl LT overproduction that participates in the pathogenesis of aspirin-induced asthma." | 5.08 | Bronchial hyperresponsiveness, hypersensitivity to analgesics and urinary leukotriene E4 excretion in patients with aspirin-intolerant asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Nakabayashi, M; Nakagawa, H; Sakamoto, H; Sakamoto, M; Shoji, T; Tajimab, T; Yamawaki, Y; Yoshida, S, 1998) |
| "This study was designed to investigate the protective effect of acyclovir on airway responsiveness to the sulpyrine provocation test and to investigate whether this protective activity is associated with a reduction in aspirin-induced excretion of urinary leukotriene E4 (u-LTE4 ), a marker of cysteinyl leukotriene (LT) overproduction that participates in the pathogenesis of aspirin-induced asthma." | 5.08 | Effect of acyclovir on bronchoconstriction and urinary leukotriene E4 excretion in aspirin-induced asthma. ( Akahori, K; Amayasu, H; Hasegawa, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Yamawaki, Y; Yoshida, S, 1998) |
| "The increase in nasal symptoms in aspirin-sensitive patients with asthma after aspirin ingestion is associated with increases in nasal tryptase, histamine, and cysteinyl leukotriene levels." | 5.07 | Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Igarashi, Y; Kaliner, MA; Lilly, CM; Rosenberg, MA; Rubin, P; White, MV, 1994) |
| " In aspirin-sensitive patients, acetylsalicylic acid causes an asthmatic reaction which typically lasts for 2 h or more after exposure." | 5.07 | Time-limited protective effect of inhaled frusemide against aspirin-induced bronchoconstriction in aspirin-sensitive asthmatics. ( Bianco, S; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Spagnotto, S; Vaghi, A, 1994) |
| "Oral challenge with aspirin or potential cross-reacting substances (including other nonsteroidal anti-inflammatory drugs [NSAIDs] or food and drug additives) is an effective method for establishing the presence of sensitivity to these substances in asthmatic subjects." | 5.07 | Oral challenges to detect aspirin and sulfite sensitivity in asthma. ( Simon, RA, 1994) |
| "We evaluated the effect of ONO-1078, a selective leukotriene-C4, -D4, and -E4-receptor antagonist, on bronchoconstriction intensity during inhalation challenge with dipyrone (a pyrazolone derivative) in six aspirin-sensitive asthmatics." | 5.07 | Inhibition of analgesic-induced asthma by leukotriene receptor antagonist ONO-1078. ( Dohi, Y; Kiuchi, H; Kuramitsu, K; Nagata, M; Sakamoto, Y; Tabe, K; Yamamoto, H; Yamamoto, K, 1994) |
| "The cysteinyl leukotrienes may play a central part in the mechanisms of aspirin-sensitive asthma." | 5.07 | Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. ( Arm, JP; Bell, GS; Foster, S; Lee, TH; MacMillan, R; Nasser, SM; Spruce, KE; Williams, AJ, 1994) |
| " To investigate whether prostaglandin production could also modulate the bronchial antireactive activity of this diuretic drug, we investigated the effect of inhaled lysine acetylsalicylate (162 mg) and of furosemide (18 mg), alone and in combination, on the bronchial obstructive response to ultrasonically nebulized water in asthmatic patients." | 5.07 | Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate. ( Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A, 1993) |
| " The presence of iLXA4 was also evaluated in vivo in aspirin-sensitive asthmatic patients who, in a randomized, double-blind crossover design, underwent nasal lavage after they each ingested a predetermined threshold dose of aspirin or placebo." | 5.07 | Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA. ( Bertram, S; Drazen, JM; Fischer, A; Israel, E; Levy, BD; Serhan, CN; Tai, HH, 1993) |
| "We have recently shown that oral aspirin provocation leads to an increase in LTE4 and a reduction in 11-dehydro-TXB2 levels in urine of patients with aspirin induced-asthma (AIA)." | 5.07 | Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge. ( Dworski, R; Nizankowska, E; Oates, JA; Sheller, JR; Sladek, K; Soja, J; Szczeklik, A, 1994) |
| "Recently, we have reported that a nebulized solution of sodium cromoglycate (SCG) (Intal), a well known antiallergic agent, has an acute bronchodilator effect in patients with aspirin-induced asthma (AIA)." | 5.07 | [Amlexanox has an acute bronchodilator effect in patients with aspirin-induced asthma (AIA)]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Satou, A; Taniguchi, M; Toyoshima, M, 1993) |
| "A subset of persons with asthma develop bronchospasm, naso-ocular, gastrointestinal, and/or dermal reactions after ingesting aspirin (ASA) or agents with the capacity to inhibit cyclooxygenase." | 5.07 | The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. ( Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Israel, E; Lilly, CM; Rosenberg, MA; Rubin, P; Shapiro, J, 1993) |
| "The findings indicate that ongoing leukotriene production may be one cause of persistent airway obstruction in aspirin sensitive asthmatic subjects and that they may benefit from treatment with a leukotriene receptor antagonist." | 5.07 | Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. ( Dahlén, B; Dahlén, SE; Margolskee, DJ; Zetterström, O, 1993) |
| "Although the mechanism of aspirin-induced asthma and rhinitis is unknown, it has been suggested that adverse nasal and bronchial reactions are caused by an increased production of lipoxygenase products." | 5.07 | Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients. ( Bulbena, O; Gelpí, E; Montserrat, JM; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J, 1992) |
| "The FEV1 and urinary leukotriene E4 (LTE4) concentrations were determined in six aspirin-sensitive and six non-aspirin-sensitive asthmatic subjects before and after inhalation challenge with lysine-aspirin or placebo solution." | 5.07 | Urinary leukotriene E4 after lysine-aspirin inhalation in asthmatic subjects. ( Black, C; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Markendorf, A; Schmitz-Schumann, M; Tagari, P, 1992) |
| " However, we have found that some patients with aspirin-intolerant asthma (AIA) show significant improvement soon after a single inhalation of SCG nebulized solution." | 5.07 | [Sodium cromoglycate nebulized solution has an acute bronchodilative effect in patients with aspirin-intolerant asthma (AIA)]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1992) |
| " The goal of the present study was to determine if the inhalation of furosemide would inhibit the bronchoconstriction resulting from the inhalation of lysine-aspirin in aspirin-sensitive asthmatics." | 5.07 | Effect of inhaled furosemide on the bronchial response to lysine-aspirin inhalation in asthmatic subjects. ( Croce, M; Cukier, A; Light, RW; Teixeira, LR; Terra-Filho, M; Vargas, FS, 1992) |
| "Urinary leukotriene E4 (LTE4) concentrations have been measured in six asthmatic patients with aspirin sensitivity and in five asthmatic subjects tolerant of aspirin, before and after provocation with aspirin or placebo." | 5.07 | Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. ( Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P, 1991) |
| "We have determined the effect of prior inhalation of the LTD4 antagonist SK&F 104353 on the response to aspirin ingestion in six aspirin-sensitive asthmatic subjects (five women and one man 31 to 54 yr of age) in a randomized, double-blind, cross-over, placebo-controlled study." | 5.07 | The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma. ( Christie, PE; Lee, TH; Smith, CM, 1991) |
| "Aspirin (ASA) and other non-steroidal anti-inflammatory drugs, which are cyclooxygenase (COX) inhibitors, precipitate asthmatic attacks in ASA-intolerant patients, while sodium salicylate, hardly active on COX by itself, is well tolerated by these patients." | 5.06 | Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients. ( Dworski, R; Nizankowska, E; Soja, J; Szczeklik, A, 1990) |
| "Treatment of inflammatory diseases of asthmatics can be a serious problem since some patients show intolerance to aspirin and other non-steroidal, anti-inflammatory drugs that are cyclooxygenase inhibitors." | 5.06 | Choline magnesium trisalicylate in patients with aspirin-induced asthma. ( Dworski, R; Nizankowska, E; Szczeklik, A, 1990) |
| "Eight patients are described who fulfill the criteria for the triad of asthma, nasal polyposis, and aspirin hypersensitivity who have been treated with oral chrysotherapy from 7 to 17 months." | 5.06 | Oral gold therapy in steroid-dependent asthma, nasal polyposis, and aspirin hypersensitivity. ( McNeil, DL, 1990) |
| "Ten aspirin (ASA)-sensitive patients with asthma underwent double-blind, placebo-controlled oral challenges with salsalate followed by ASA-sensitive confirmatory challenges." | 5.06 | Salsalate cross-sensitivity in aspirin-sensitive patients with asthma. ( Goldlust, MB; Hougham, AJ; Schrank, PJ; Stevenson, DD; Wilson, RR, 1990) |
| "Inhalation of an aerosolized solution of lysine-aspirin has previously been described as a safer technique than oral challenge with aspirin for the diagnosis of aspirin-sensitive asthma." | 5.06 | Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine. ( Foord, R; Holgate, ST; Phillips, GD, 1989) |
| "Inhibition of prostacyclin biosynthesis by aspirin might be expected to promote asthmatic attacks in aspirin-intolerant patients." | 5.06 | The effect of prostacyclin on asthma precipitated by aspirin. ( Czerniawska-Mysik, G; Nizankowska, E; Szczeklik, A, 1987) |
| "One hundred and fifty-six German, Italian and Polish patients with confirmed aspirin-induced asthma underwent open oral challenges with increasing doses of tartrazine up to 25 mg." | 5.06 | Intolerance to tartrazine in aspirin-induced asthma: results of a multicenter study. ( Bianco, S; Damonte, C; Juhl, E; Menz, G; Robuschi, M; Schmitz-Schumann, M; Serwonska, M; Szczeklik, A; Virchow, C, 1988) |
| "Inhibition of prostacyclin biosynthesis by aspirin might be expected to promote asthmatic attacks in aspirin-intolerant patients." | 5.06 | Lack of effect of i.v. prostacyclin on aspirin-induced asthma. ( Czerniawska-Mysik, G; Nizankowska, E; Szczeklik, A, 1986) |
| "NSAID-Exacerbated respiratory disease (also known as Samter's or Widal's triad, aspirin-exacerbated respiratory disease) is characte- rized by asthma, nasal polyposis and hypersensitivity to NSAIDs." | 5.05 | [Widal's triad : clinical manifestations, pathophysiology and therapeutic advances]. ( Jandus, P; Landis, BN; Vandenberghe-Dürr, S, 2020) |
| "Adverse reactions to aspirin in asthmatic patients have been widely described in the past." | 5.05 | Failure of children with asthma to respond to daily aspirin therapy. ( Cummings, NP; Morris, HG; Strunk, RC, 1983) |
| "In six adult patients with bronchial asthma aspirin in a single dose of 0." | 5.05 | Asthma improved by aspirin-like drugs. ( Nizankowska, E; Szczeklik, A, 1983) |
| "Because aspirin (ASA) is often reported to have an adverse effect on pulmonary function in children with chronic asthma, acetaminophen is commonly used as an ASA substitute in these children." | 5.05 | Adverse pulmonary responses to aspirin and acetaminophen in chronic childhood asthma. ( Fischer, TJ; Gartside, PS; Guilfoile, TD; Kearns, GL; Kesarwala, HH; Moomaw, CJ; Winant, JG, 1983) |
| "Eight asthmatics with respiratory intolerance to NSAIDs and two subjects (one asthmatic, one healthy) only sensitive (asthma) to pyrazolone drugs were challenged under single-blind conditions with a new NSAID, carprofen." | 5.05 | Tolerance of carprofen in patients with asthma caused by non-steroidal anti-inflammatory drugs. ( Bianco, S; Pasargiklian, M; Robuschi, M; Simone, P; Vaghi, A, 1985) |
| "We studied the effects of intravenous injection of hydrocortisone, as compared to its solvent, in 31 patients with aspirin-induced asthma." | 5.05 | Hydrocortisone and airflow impairment in aspirin-induced asthma. ( Czerniawska-Mysik, G; Nizankowska, E; Sek, S; Szczeklik, A, 1985) |
| "First described as a component of a triad seen among adults with nonallergic asthma and nasal polyps, aspirin sensitivity has subsequently been documented as a frequent concomitant of a wide range of patients with chronic asthma." | 5.04 | Analgesic sensitivity in children with asthma. ( Weinberger, M, 1978) |
| "Oral challenge tests with acetylsalicylic acid, tartrazine or benzoic acid were performed in 7 intolerant asthmatic patients after a 3-day treatment with either orally taken ketotifen (1 mg twice daily) or inhaled disodium cromoglycate (20 mg four times daily) at random." | 5.04 | Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. ( Wüthrich, B, 1979) |
| "The control of asthma by therapy with cromolyn sodium was studied in 28 adults with late-onset asthma associated with hypersensitivity to aspirin and nasal polyps." | 5.04 | Cromolyn sodium in the treatment of asthma associated with aspirin hypersensitivity and nasal polyps. ( Gwin, E; Kerby, GR; Ruth, WE, 1977) |
| "Forty-five patients with moderately severe perennial bronchial asthma were challenged by ingestion of: acetylsalicyclic acid (ASA); 4 azo dyes (tartrazine, sunset yellow, amaranth, and ponceau); 3 non-azo dyes (erythrosine, brilliant blue, and indigotin); sodium benzoate (NaB); parahydroxybenzoic acid (OHBA); butylated hydroxyanisole (BHA); and butylated hydroxytoluene (BHT)." | 5.04 | Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics. ( Hoffman, M; Nelson, HS; Raine, DA; Weber, RW, 1979) |
| "Oral aspirin challenge was used to detect unrecognized aspirin intolerance in a select group of 50 asthmatic patients who denied aspirin intolerance." | 5.04 | Refractory period to aspirin in a patient with aspirin-induced asthma. ( Lockey, RF; Zeiss, CR, 1976) |
| "Most previously reported individuals with acetylsalicylic acid (aspirin, ASA)-induced asthma have been adults." | 5.04 | Aspirin intolerance in chronic childhood asthma: Detected by oral challenge. ( Coulson, A; Rachelefsky, GS; Siegel, SC; Stiehm, ER, 1975) |
| "In four subjects with exercise-induced asthma, aspirin and placebo were administered prior to exercise in a double blind study." | 5.04 | Aspirin and exercise-induced asthma. ( Hamosh, P; Taveira da Silva, AM, 1976) |
| "Aspirin-exacerbated respiratory disease is a chronic and treatment-resistant disease, characterized by the presence of eosinophilic rhinosinusitis, nasal polyposis, bronchial asthma, and nonsteroidal anti-inflammatory drugs hypersensitivity." | 4.98 | Aspirin exacerbated respiratory disease: Current topics and trends. ( Guaní-Guerra, E; Moreno-Paz, FJ; Rodríguez-Jiménez, JC; Terán, LM, 2018) |
| "To examine the roots of asthma across different ages, including atopy, the role of the microbiome and viral infections, and comorbidities and confounders, such as obesity, aspirin-exacerbated respiratory disease, neutrophilic asthma, cigarette smoking, and the possibility of an asthma-chronic obstructive pulmonary disease overlap syndrome." | 4.98 | Heterogeneity and the origins of asthma. ( Grayson, MH; Scherzer, R, 2018) |
| " This report describes a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma also known as Samter-Beer triad combining nasal polyps, asthma, and aspirin allergy leading to vasospasm and myocardial infarction." | 4.98 | Kounis syndrome induced by oral intake of aspirin: case report and literature review. ( Cherti, M; Dakka, T; Doghmi, N; Hangouche, AJE; Lamliki, O; Oukerraj, L; Zarzur, J, 2018) |
| "Aspirin-exacerbated respiratory disease (AERD) refers to the combination of asthma, chronic rhinosinusitis with nasal polyposis, and acute upper and lower respiratory tract reactions to the ingestion of aspirin (acetylsalicylic acid, ASA) and other cyclooxygenase-1 inhibiting non-steroidal anti-inflammatory drugs." | 4.95 | Aspirin-exacerbated respiratory disease and current treatment modalities. ( Cingi, C; Kar, M; Muluk, NB; Sakalar, EG, 2017) |
| "Aspirin-exacerbated respiratory disease (AERD) represents a severe form of chronic rhinosinusitis (CRS) characterized by nasal polyposis, bronchial asthma, and aspirin intolerance." | 4.93 | The Role of Surgery in Management of Samter's Triad: A Systematic Review. ( Adelman, J; Krouse, JH; McLean, C; Shaigany, K, 2016) |
| "Aspirin-exacerbated respiratory disease (AERD) is a late onset condition characterized by the Samter triad (aspirin sensitivity [as well as sensitivity to any nonselective cyclooxygenase inhibitor], nasal polyps, asthma) and additional features, including eosinophilic chronic rhinosinusitis, hypereosinophilia, anosmia, frequent absence of atopy, and, intolerance to ingestion of red wine and other alcoholic beverages." | 4.93 | Aspirin-exacerbated respiratory disease: Prevalence, diagnosis, treatment, and considerations for the future. ( Borish, L; Kennedy, JL; Stoner, AN, 2016) |
| "The prevalence and mean provocative dose of oral aspirin (MPDA) triggering respiratory reactions in people with asthma have been inconsistently reported, and the relationship between NSAID-exacerbated respiratory disease (NERD) and asthma morbidity was less well quantified." | 4.91 | NSAID-exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity. ( Donnan, PT; Guthrie, B; Jackson, C; Lipworth, BJ; Morales, DR; Santiago, VH, 2015) |
| "Hypersensitivity to acetylsalicylic acid (ASA) is characterized by the co-occurrence of symptoms so-called aspirin triad, which include bronchial asthma, chronic rhinitis and sinusitis and the nasal mucosa polyps." | 4.91 | [Hypersensitivity to acetylsalicylic acid]. ( Skrętkowicz, J; Wojtczak, A, 2015) |
| "Aspirin-exacerbated diseases are important examples of drug hypersensitivities and include aspirin-exacerbated respiratory disease (AERD), aspirin- or non-steroidal anti-inflammatory drug (NSAID)-induced urticaria/angioedema, and aspirin- or NSAID-induced anaphylaxis." | 4.91 | Aspirin-Exacerbated Diseases: Advances in Asthma with Nasal Polyposis, Urticaria, Angioedema, and Anaphylaxis. ( Buchheit, K; Cahill, KN; Stevens, W, 2015) |
| " Several clinical phenotypes often leading to uncontrolled disease, including adult nasal polyposis, aspirin-exacerbated respiratory disease, and allergic fungal rhinosinusitis, are characterized by a common endotype: a TH2 bias is associated with a higher likelihood of comorbid asthma and recurrence after surgical treatment." | 4.91 | Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis. ( Bachert, C; Gevaert, P; Zhang, L, 2015) |
| "Asthma has many triggers including rhinosinusitis; allergy; irritants; medications (aspirin in aspirin-exacerbated respiratory disease); and obesity." | 4.90 | Identifying asthma triggers. ( Ferguson, BJ; McCarty, JC, 2014) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) cause bronchospasm in susceptible patients with asthma, often termed aspirin-exacerbated respiratory disease (AERD), with the risk being greatest after acute exposure." | 4.90 | Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials. ( Donnan, PT; Guthrie, B; Jackson, C; Lipworth, BJ; Morales, DR; Santiago, VH, 2014) |
| "Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently coexist and are always present in patients with aspirin exacerbated respiratory disease (AERD)." | 4.90 | Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity. ( Machado-Carvalho, L; Picado, C; Roca-Ferrer, J, 2014) |
| "NSAIDs-including aspirin (ASA)-that inhibit cyclooxygenase (COX)-1 induce nonallergic hypersensitivity reactions consisting of attacks of rhinitis and asthma." | 4.85 | Aspirin sensitivity and desensitization for asthma and sinusitis. ( Stevenson, DD, 2009) |
| "The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma." | 4.85 | Gene-expression signatures of nasal polyps associated with chronic rhinosinusitis and aspirin-sensitive asthma. ( Metson, R; Platt, M; Stankovic, K, 2009) |
| " It has also been associated with a female predominance, aspirin-sensitive bronchospasm, and nasal polyposis." | 4.85 | Is intrinsic asthma synonymous with infection? ( Busse, WW; Dahlberg, PE, 2009) |
| "Although acetylsalicylic acid is prescribed for a broad range of diseases, it can induce a wide array of clinically recognized hypersensitivity reactions, including aspirin-intolerant asthma (AIA) with rhinitis and aspirin-intolerant urticaria (AIU) with anaphylaxis." | 4.84 | What do we know about the genetics of aspirin intolerance? ( Kim, SH; Palikhe, NS; Park, HS, 2008) |
| " From recent studies on the U-LTE(4) associated with adult stable asthma we identified four factors for hyperleukotrieneuria, namely, aspirin intolerance, eosinophilic nasal polyposis (ENP), vasculitis, and severe asthma." | 4.84 | Hyperleukotrieneuria in patients with allergic and inflammatory disease. ( Akiyama, K; Higashi, N; Mita, H; Ono, E; Taniguchi, M, 2008) |
| "Leukotriene overproduction is the major characteristic of aspirin-intolerant asthma (AIA)." | 4.84 | Pharmacogenetics of aspirin-intolerant asthma. ( Choi, JH; Hur, GY; Kim, SH; Park, HS, 2008) |
| "Aspirin-induced asthma (AIA) and aspirin-induced urticaria/ angioedema (AIU) are two major aspirin-related allergies." | 4.83 | Genetic markers for differentiating aspirin-hypersensitivity. ( Kim, SH; Park, HS, 2006) |
| "To summarize recent findings related to the pathogenic mechanisms of aspirin-induced asthma with emphasis on molecular genetic mechanisms." | 4.83 | Pathogenesis of nonsteroidal antiinflammatory drug-induced asthma. ( Kim, SH; Park, HS, 2006) |
| " We report a patient with asthma, aspirin allergy, and nasal polyps who developed bronchospasm following the administration of intravenous methylprednisolone sodium succinate during an acute asthmatic attack." | 4.83 | Worsening of asthma with systemic corticosteroids. A case report and review of literature. ( Jackson, R; Reddymasu, S; Sheth, A, 2006) |
| "The full clinical picture of aspirin intolerance--the association of aspirin-induced bronchial asthma (with severe acute asthma attacks), aspirin sensitivity and nasal polyps--is commonly summarized as the 'Samter triad'." | 4.83 | Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements. ( Klimek, L; Pfaar, O, 2006) |
| "Aspirin and other nonsteroidal anti-inflammatory drugs that inhibit COX-1 induce unique nonallergic reactions, consisting of attacks of rhinitis and asthma." | 4.83 | Clinical and pathologic perspectives on aspirin sensitivity and asthma. ( Stevenson, DD; Szczeklik, A, 2006) |
| " Endophenotypes are traits, such as bronchiole hyperactivity, atopy, and aspirin intolerant asthma, which have a strong genetic component and are risk factors for a variety of more complex outcomes that may include disease states." | 4.83 | G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective. ( Bossé, Y; Burnham, WM; Capra, V; Cole, DE; Hudson, TJ; Rovati, GE; Siminovitch, KA; Takasaki, J; Thompson, MD, 2006) |
| "The relationship of aspirin sensitivity to urticaria is complex." | 4.82 | Aspirin sensitivity and urticaria. ( Grattan, CE, 2003) |
| "Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis, nasal polyposis, asthma and precipitation of asthma, and rhinitis attacks after ingestion of aspirin (ASA) and most other nonsteroidal antiinflammatory drugs (NSAIDs)." | 4.82 | Natural history and clinical features of aspirin-exacerbated respiratory disease. ( Fahrenholz, JM, 2003) |
| "In some asthmatic individuals, aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygen-ase 1 (COX-1) exacerbate the condition." | 4.82 | Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. ( Stevenson, DD; Szczeklik, A, 2003) |
| "Aspirin (ASA) is an important cause of asthma so that ASA induced asthma (AIA) is considered a disease." | 4.82 | [Asthma and aspirin]. ( Frati, F; Gani, F; Marcucci, F; Schiappoli, M; Senna, G, 2003) |
| "To review the safety of cyclooxygenase-2 (COX-2) inhibitors in asthma patients with aspirin hypersensitivity." | 4.82 | Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity. ( Fernández, C; West, PM, 2003) |
| "Aspirin-induced asthma (AIA) is a distinct clinical entity characterised by hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) typically occurring in the form of asthma and severe rhinosinusitis." | 4.82 | [Asthma with hypersensitivity to aspirin]. ( Nizankowska-Mogilnicka, E, 2003) |
| "Aspirin-exacerbated respiratory disease (AERD) is an adult-onset condition that manifests as asthma, rhinosinusitis/nasal polyps, and sensitivity to aspirin and other cyclooxygenase-1 (COX-1)-inhibitor nonsteroidal anti-inflammatory drugs (NSAIDs)." | 4.82 | Adverse respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs. ( Simon, RA, 2004) |
| "In up to 10% of patients with bronchial asthma, aspirin and other nonsteroidal antiinflammatory drugs precipitate asthmatic attacks." | 4.82 | Aspirin intolerance and the cyclooxygenase-leukotriene pathways. ( Kiełbasa, B; Nizankowska-Mogilnicka, E; Sanak, M; Szczeklik, A, 2004) |
| "To reassess the prevalence of aspirin induced asthma and other issues related to the syndrome." | 4.82 | Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. ( Costello, J; Hodge, L; Jenkins, C, 2004) |
| "Aspirin (acetylsalicylic acid)-induced asthma (AIA) consists of the clinical triad of asthma, chronic rhinosinusitis with nasal polyps, and precipitation of asthma and rhinitis attacks in response to aspirin and other NSAIDs." | 4.82 | Aspirin-induced asthma: clinical aspects, pathogenesis and management. ( Hamad, AM; Knox, AJ; Sutcliffe, AM, 2004) |
| "To provide a diagnostic strategy for evaluating and treating patients with aspirin sensitivity, with additional consideration for issues specific to patients with coronary artery disease (CAD)." | 4.82 | Aspirin sensitivity: implications for patients with coronary artery disease. ( Gollapudi, RR; Simon, RA; Stevenson, DD; Teirstein, PS, 2004) |
| "Aspirin-sensitive asthma is a common and often underdiagnosed disease affecting up to 20% of the adult asthmatic population." | 4.82 | Aspirin-sensitive asthma. ( Gillis, D; Kette, F; Morwood, K; Smith, W, 2005) |
| "In 2-23% of adults with asthma, and rarely in children with asthma, aspirin (acetylsalicylic acid) and non-steroidal anti-inflammatory drugs (NSAIDs) cause asthma exacerbations." | 4.82 | Pathogenesis and management of aspirin-intolerant asthma. ( Haahtela, T; Kohno, S; Matsuse, H; Obase, Y; Shimoda, T, 2005) |
| "Available clinical data on aspirin-sensitive asthma (ASA) indicate that ASA patients have certain disturbances in the nervous, endocrine, immune and other body systems." | 4.81 | Aspirin-sensitive asthma due to diffuse neuroendocrine system pathology. ( Evsyukova, HV, 2002) |
| "Aspirin-sensitive asthmatics experience a wide variety of symptoms, ranging from rhinitis to life-threatening bronchospasms, after the ingestion of aspirin or nonsteroidal antiinflammatory drugs (NSAIDs)." | 4.81 | Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics. ( Pontikes, PJ; Volkman, JA, 2002) |
| "Relevant articles in the medical literature were derived from searching the MEDLINE database with key terms aspirin-sensitive asthma, cyclo-oxygenase enzymes 1 and 2." | 4.81 | Sensitivity to nonsteroidal anti-inflammatory drugs. ( Namazy, JA; Simon, RA, 2002) |
| "Aspirin (acetylsalicylic acid) and other nonsteroidal anti-inflammatory drugs (NSAIDs) cause deterioration in respiratory function in approximately 10% of adults with asthma and a smaller proportion of children with asthma." | 4.81 | The use of analgesics in patients with asthma. ( Levy, S; Volans, G, 2001) |
| "In about 10% of adult patients with asthma, aspirin and other nonsteroidal anti-inflammatory drugs precipitate attacks of dyspnoea." | 4.81 | A new insight into aspirin-induced asthma. ( Jawien, J, 2002) |
| "Interesting findings relating to aspirin-induced asthma recently emerged." | 4.81 | Aspirin-induced rhinitis and asthma. ( Nizankowska, E; Sanak, M; Swierczynska, M; Szczeklik, A, 2001) |
| "We described asthma with sensitivity to aspirin and other nonsteroidal anti-inflammatory drugs (NSAID)." | 4.81 | [Asthma with aspirin intolerance]. ( Krasnowska, M, 2002) |
| "In the United States, the documented prevalence of childhood asthma has increased since 1970, but the rate of this increase accelerated upward beginning in the early 1980s when the use of pediatric aspirin decreased." | 4.80 | Hypothesis: decreased use of pediatric aspirin has contributed to the increasing prevalence of childhood asthma. ( Busse, WW; Lemanske, RF; Varner, AE, 1998) |
| "In some patients with asthma, aspirin (ASA) and all nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase enzymes (cyclooxygenase-1 and -2) precipitate asthmatic attacks and naso-ocular reactions." | 4.80 | Aspirin-induced asthma: advances in pathogenesis and management. ( Stevenson, DD; Szczeklik, A, 1999) |
| "The paper describes the clinical characteristics of patients with aspirin-induced asthma and/or urticaria, angioedema, shock, the results of the challenge tests and the evolution of this disease." | 4.80 | [Aspirin: allergy or intolerance]. ( Pradalier, A; Vincent, D, 2000) |
| " Reports that PGE2 inhibits airways response in bronchial provocation with lysine aspirin, allow to believe that PGE2 plays a role in pathogenesis of aspirin induced asthma." | 4.79 | [Role of prostaglandins F and E in regulation of bronchial activity]. ( Mastalerz, L, 1995) |
| "Aspirin-sensitive rhinosinusitis is a non-allergic, non-infectious perennial eosinophilic rhinitis starting in middle age and rarely seen in children." | 4.79 | Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis. ( Schapowal, AG; Schmitz-Schumann, M; Simon, HU, 1995) |
| " These agents produced beneficial effects in cold-, exercise-, and aspirin-induced asthma, as well as clinical asthma." | 4.79 | Leukotriene inhibitors and antagonists in asthma. ( Spector, SL, 1995) |
| "Several lines of evidence support the central role of the cysteinyl leukotrienes in aspirin-sensitive asthma, although their cellular source is unknown." | 4.79 | Mast cell effector mechanisms. ( Lane, SJ; Lee, TH, 1996) |
| "Aspirin-induced asthma is a distinct clinical syndrome which affects about 10% of adult asthmatics." | 4.78 | The cyclooxygenase theory of aspirin-induced asthma. ( Szczeklik, A, 1990) |
| "Patients with asthma and nasal polyps have been warned to avoid aspirin because of a tendency to develop hypersensitivity reactions." | 4.77 | Desensitization to aspirin in aspirin-sensitive patients with rhino-sinusitis and asthma: a review. ( Knight, A, 1989) |
| "Aspirin-induced asthma (AIA) is a distinct clinical syndrome, present in about 10% of adult asthmatics." | 4.77 | Aspirin-induced asthma: new insights into pathogenesis and clinical presentation of drug intolerance. ( Szczeklik, A, 1989) |
| " It seems likely that this eicosanoid-mucus secretion relationship is very important in all forms of asthma, but most particularly in aspirin-related asthma." | 4.77 | The role of eicosanoids in respiratory mucus hypersecretion. ( Kaliner, MA; Lundgren, JD; Shelhamer, JH, 1985) |
| "The historic triad of bronchial asthma, nasal polyposis, and intolerance to aspirin and related chemicals, recently designated as Samter's syndrome, is an inflammatory condition of unknown etiology and pathogenesis." | 4.77 | Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter's syndrome. ( Zeitz, HJ, 1988) |
| " An intolerance to ASS mostly becomes manifest as bronchial asthma--sometimes up to a status asthmaticus: it is frequently combined with vasomotoric rhinopathia and nasal polyps (so-called "aspirin triad") or as urticaria and angio-edema, seldom as a shock reaction." | 4.77 | [Acetylsalicylic acid pseudoallergy: an anomaly of thrombocyte function?]. ( Wüthrich, B, 1988) |
| "Tartrazine, a common additive in foods and drugs, often causes adverse reactions such as recurrent urticaria, angioedema, and asthma and is frequently implicated in hyperkinesis." | 4.77 | Clinical spectrum of adverse reactions to tartrazine. ( Collins-Williams, C, 1985) |
| "Aspirin intolerance is particularly common in asthmatic patients who additionally have chronic rhinitis and/or nasal polyps." | 4.77 | Aspirin-sensitive asthma. ( Mathews, KP; McLean, JA; Slepian, IK, 1985) |
| " Recent elucidations of pathophysiologic mechanisms involving the autonomic nervous system, cyclic nucleotide metabolism, and arachnoidonic biochemistry give us a better understanding of the similarities and unique differences among asthma events related to exercise, aspirin, emotions, occupational environments, atmospheric conditions, and respiratory tract infections." | 4.76 | The pathophysiology of asthma. Extrinsic influences other than immunologic. ( Goetter, WE, 1984) |
| "Aspirin intolerance manifests itself as an acute urticaria-angioedema, bronchospasm, severe rhinitis, or shock occurring within three hours of aspirin ingestion." | 4.76 | Aspirin and allergic diseases: a review. ( Settipane, GA, 1983) |
| " Association of bronchial asthma, nasal pathology and intolerance to aspirin is a unique syndrome." | 4.75 | Aspirin intolerance--a review. ( Abrishami, MA; Thomas, J, 1977) |
| "Aspirin desensitization (AD) is effective in relieving asthma and sinonasal outcomes in patients with non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD)." | 4.31 | Aspirin desensitization following endoscopic sinus surgery is effective in patients with nonsteroidal antiinflammatory drug exacerbated respiratory disease. ( Anadolu, Y; Atmiş, EÖ; Aydin, Ö; Çelik, GE; Yorulmaz, İ, 2023) |
| "Aspirin-exacerbated respiratory disease (AERD) is a unique and often clinically severe disease affecting a subgroup of adults with asthma and chronic rhinosinusitis with nasal polyposis." | 4.31 | Mechanistic and clinical updates in AERD: 2021-2022. ( Cahill, KN; Stevens, WW, 2023) |
| " Quantitative and descriptive analyses of age, gender, nationality, presence of polyps, aspirin sensitivity, presence of urticaria, asthma, and allergies were performed." | 4.31 | Demographic and clinical profile of patients with chronic rhinosinusitis in Saudi Arabia. ( Alanazy, F; Alfallaj, R; Almousa, H; Aloulah, M; Alrasheed, A; Alromaih, S; Alroqi, AS; Alsaleh, S; Dousary, SA; Ismail, D; Mahjoub, S; Obaid, SB, 2023) |
| "Aspirin-exacerbated respiratory disease (AERD) is a phenotype of severe asthma, but its disease course has not been well documented compared with that of aspirin-tolerant asthma (ATA)." | 4.31 | Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort. ( Kim, C; Lee, E; Lee, HY; Lee, Y; Park, HS; Park, RW; Woo, SD; You, SC, 2023) |
| "Aspirin-exacerbated respiratory disease (AERD) consists of chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and hypersensitivity to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)." | 4.31 | Association Between Aspirin-Exacerbated Respiratory Disease and Atherosclerotic Cardiovascular Disease: A Retrospective Review of US Claims Data. ( Adame, MJ; Kuo, YF; Raji, M; Shan, Y; Tripple, JW; Zhang, Y, 2023) |
| "Platelets are key contributors to allergic asthma and aspirin-exacerbated respiratory disease (AERD), an asthma phenotype involving platelet activation and IL-33-dependent mast cell activation." | 4.31 | Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease. ( Amin, T; Boyce, JA; Cahill, KN; Feng, C; Foer, D; Hayashi, H; Lai, J; Laidlaw, TM; Lin, A; Liu, T; McGill, A; Nagai, J; Newcomb, DC; Niswender, KD; Snyder, WE; Tani, Y, 2023) |
| "Non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD) is characterized by the triad of chronic rhinosinusitis with nasal polyp, asthma, and aspirin (ASA) or NSAID hypersensitivity." | 4.12 | Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease. ( Sompornrattanaphan, M; Tantilipikorn, P; Thongngarm, T; Wongsa, C, 2022) |
| "Nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) asthma is characterized by chronic rhinosinusitis and intolerance of aspirin and other COX1 inhibitors." | 4.02 | Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease. ( Bochenek, G; Gielicz, A; Jakiela, B; Plutecka, H; Przybyszowski, M; Rebane, A; Sladek, K; Soja, J, 2021) |
| " CRSwNP may be associated with comorbidity, mainly concerning asthma, aspirin intolerance, and allergy." | 3.96 | Clinical-Cytological-Grading and phenotyping in patients with chronic rhinosinusitis with nasal polyps: the relevance in clinical practice. ( Cassano, M; Ciprandi, G; Gelardi, M; Porro, G; Quaranta, N; Quaranta, V; Study Group On CRSwNP, I, 2020) |
| "This study involved 306 subjects, referred to the Be'sat hospital in Kurdistan Province, which were divided into three groups, (i) Aspirin Induced Asthma (AIA), (ii) Aspirin Tolerant Asthma (ATA), and (iii) healthy subjects as control." | 3.96 | Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in a Kurd Population. ( Abdi, M; Jalili, A; Kalmarzi, RN; Kooti, W; Malik, YS; Nouri, B; Rahmani, MR; Rezaee, MA, 2020) |
| " The coexistence of CRS, bronchial asthma and aspirin intolerance (aspirin triad) is an adverse prognostic factor with higher risk of recurrences." | 3.91 | Analysis of the impact of bronchial asthma and hypersensitivity to aspirin on the clinical course of chronic sinusitis with nasal polyps. ( Dąbrowska, K; Fendler, W; Pagacz, K; Pietruszewska, W; Podwysocka, M, 2019) |
| "The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity." | 3.88 | [Is celecoxib a safe alternative for the Fernand Widal syndrome?] ( De Blay, F; Guenard-Bilbaut, L; Metz-Favre, C; Schaller, A, 2018) |
| "Compared with the polyposis only group, hydrogen peroxide consumption, glutathione S-transferase, vitamin E and malondialdehyde were lower in the asthma group." | 3.88 | Role of asthma and intolerance to acetylsalicylic acid on the redox profile in nasal polyp tissue. ( Benfato, MS; Canata, DAM; da Silva, GLF; Hackenhaar, FS; Salomon, TB; Schüller, ÁK; Teixeira, C, 2018) |
| "Aspirin exacerbated asthma (AEA) affects approximately 10% of the asthmatic population." | 3.88 | Asthma exacerbation by aspirin and chemical additives: use of a nucleotide template model to investigate potential mechanisms. ( Williams, WR, 2018) |
| " We also demonstrated that hypereosinophilia, asthma, and aspirin intolerance may increase the OR differently in eosinophilic patients." | 3.85 | Prognostic value of nasal cytology and clinical factors in nasal polyps development in patients at risk: can the beginning predict the end? ( Autilio, C; Baroni, S; Battista, M; De Corso, E; De Vita, C; Galli, J; Lucidi, D; Paludetti, G; Romanello, M, 2017) |
| "Leukotrienes are proinflammatory lipid mediators that have been shown to be upregulated in several diseases, including asthma, aspirin-exacerbated respiratory disease (AERD), inflammatory bowel disease, and acute respiratory distress syndrome." | 3.85 | Leukotrienes and sex: strange bedfellows? ( Smith, LJ, 2017) |
| "Aspirin hypersensitivity associated with chronic rhinosinusitis-with or without nasal polyposis-and asthma resistant to conventional therapy defines the aspirin-exacerbated respiratory disease (AERD)." | 3.85 | Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria. ( Cutrera, R; Di Marco, A; Porcaro, F, 2017) |
| "We sought to evaluate the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on T-cell activation of the IL-4 pathway in aspirin-sensitive patients with asthma and control subjects." | 3.83 | Nonsteroidal anti-inflammatory-induced inhibition of signal transducer and activator of transcription 6 (STAT-6) phosphorylation in aspirin-exacerbated respiratory disease. ( Alam, R; Burnett, T; Faino, A; Finkas, L; Katial, RK; Liu, S; Martucci, M, 2016) |
| "In utero exposure to aspirin was associated with an increased risk of childhood asthma (adjusted odds ratio [aORs] = 1." | 3.83 | In Utero Exposure to Aspirin and Risk of Asthma in Childhood. ( Bao, J; Bao, Y; Chu, S; Huang, L; Yu, H; Zhang, J, 2016) |
| " In aspirin exacerbated respiratory disease (AERD), asthmatic symptoms are precipitated by ingestion of non-steroid anti-inflammatory drugs capable for pharmacologic inhibition of cyclooxygenase-1 isoenzyme." | 3.81 | Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics. ( Celejewska-Wójcik, N; Gielicz, A; Januszek, R; Kaszuba, M; Mastalerz, L; Oleś, K; Plutecka, H; Sanak, M; Stręk, P; Wójcik, K, 2015) |
| " We present the case of a 50-year-old male with the Samter-Beer triad of asthma, nasal polyps, and salicylate intolerance with an ST elevation myocardial infarction complicated with cardiac arrest due to multi-vessel coronary artery spasm secondary to aspirin anaphylaxis." | 3.81 | Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline. ( Ihdayhid, AR; Rankin, J, 2015) |
| "To demonstrate that quality-of-life outcomes after endoscopic sinus surgery are not compromised in patients with Samter's triad (asthma, nasal polyps, aspirin sensitivity) when compared to patients with eosinophilic chronic rhinosinusitis with nasal polyposis (eCRSwP) who are not aspirin sensitive." | 3.80 | Aspirin sensitivity does not compromise quality-of-life outcomes in patients with Samter's triad. ( Comer, BT; Jang, DW; Kountakis, SE; Lachanas, VA, 2014) |
| "Aspirin-exacerbated respiratory disease (AERD) has attracted a great deal of attention because of its association with increased asthma severity." | 3.80 | Plasma apolipoprotein H levels are different between aspirin induced respiratory diseases and aspirin tolerant asthma. ( Heo, JS; Kim, HJ; Moon, KY; Park, CS; Park, JS, 2014) |
| " Thus, functional alterations of the RAB1A gene may contribute to aspirin intolerance in asthmatic sufferers." | 3.80 | Association analysis of member RAS oncogene family gene polymorphisms with aspirin intolerance in asthmatic patients. ( Chang, HS; Choi, IS; Heo, JS; Kim, MK; Lee, JU; Park, BL; Park, CS; Park, JS; Shin, HD, 2014) |
| "Samter's triad is a well described condition manifesting as chronic rhinosinusitis with nasal polyposis, asthma and aspirin intolerance in a non-atopic individual." | 3.80 | Samter's triad with aural involvement: a novel approach to management. ( Heywood, R; Narula, A; Sethukumar, P, 2014) |
| " The impact of surgery and factors such as the presence of polyps, asthma, and aspirin sensitivity on the bacterial state are poorly understood." | 3.79 | The bacteriology of chronic rhinosinusitis and the pre-eminence of Staphylococcus aureus in revision patients. ( Bassiouni, A; Cleland, EJ; Wormald, PJ, 2013) |
| "Aspirin-exacerbated respiratory disease (AERD) has been recognized in adults with chronic asthma." | 3.79 | Samter's triad in childhood: a warning for those prescribing NSAIDs. ( Ameratunga, R; Anderson, BJ; Dalziel, S; Randall, N, 2013) |
| "Aspirin-exacerbated respiratory disease (AERD) is distinguished from aspirin-tolerant asthma/chronic sinusitis in large part by an exuberant infiltration of eosinophils that are characterized by their overexpression of metabolic pathways that drive the constitutive and aspirin-induced secretion of cysteinyl leukotrienes (CysLTs)." | 3.79 | Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease. ( Borish, L; Huyett, P; Liu, L; Negri, J; Payne, SC; Steinke, JW, 2013) |
| "Patients with chronic rhinosinusitis (CRS) and nasal polyps (NPs) may be subdivided into aspirin-sensitive (AS) and aspirin-tolerant (AT) populations." | 3.79 | Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps. ( Fountain, CR; Katial, RK; Kingdom, TT; Mudd, PA; Ramakrishnan, VR; Sillau, SH, 2013) |
| "Aspirin-intolerant asthma is a unique clinical syndrome characterized by acute bronchoconstriction following the administration of aspirin and/or non-steroidal anti-inflammatory drugs." | 3.79 | Aspirin-intolerant asthma in the Korean population: prevalence and characteristics based on a questionnaire survey. ( Chang, YS; Cho, SH; Cho, YJ; Cho, YS; Choi, BW; Jang, AS; Kim, SH; Kim, TB; Lee, JH; Moon, HB; Moon, JY; Nahm, DH; Park, CS; Park, JW; Yoon, HJ, 2013) |
| "We compared outpatients with difficult-to-treat asthma (DTA; n = 486) in a tertiary hospital for allergic diseases in central Japan with those with controlled severe asthma (n = 621) with respect to clinical factors including body mass index (BMI) and aspirin intolerance using multivariate logistic regression analysis stratified by gender and atopic phenotype." | 3.78 | Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women. ( Akiyama, K; Fukutomi, Y; Hasegawa, M; Higashi, N; Mori, A; Nakamura, H; Ono, E; Oshikata, C; Sekiya, K; Taniguchi, M; Tanimoto, H; Tsuburai, T, 2012) |
| "Since subepithelial fibrosis and protruded extracellular matrix are among the histological characteristics of polyps, the emilin/multimerin domain-containing protein 2 (EMID2) gene is speculated to be involved in the presence of nasal polyps in asthma and aspirin-hypersensitive patients." | 3.78 | Possible role of EMID2 on nasal polyps pathogenesis in Korean asthma patients. ( Bae, JS; Cheong, HS; Jang, AS; Kim, JH; Park, BL; Park, CS; Pasaje, CF; Shin, HD; Uh, ST, 2012) |
| "Nine common SNPs were genotyped in 93 AERD patients and 96 aspirin-tolerant asthma (ATA) controls." | 3.78 | Potential association of DDR1 genetic variant with FEV1 decline by aspirin provocation in asthmatics. ( Bae, JS; Cho, SH; Choi, BW; Choi, IS; Kim, JH; Kim, JY; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Pasaje, CF; Shin, HD; Uh, ST, 2012) |
| "There is no in vitro test to diagnose aspirin-intolerant asthma (AIA)." | 3.78 | Challenge of isolated sputum cells supports in vivo origin of intolerance reaction to aspirin/non-steroidal anti-inflammatory drugs in asthma. ( Daham, K; Dahlén, B; Dahlén, SE; Delin, I; Gaber, F; Gyllfors, P; Higashi, A; Higashi, N; James, A; Kumlin, M; Lindeberg, A; Skedinger, M, 2012) |
| "Aspirin-exacerbated respiratory disease (AERD) is associated with severe asthma and aspirin can cause asthma to worsen, often in the form of a severe and sudden attack." | 3.78 | Differential gene expression profile in PBMCs from subjects with AERD and ATA: a gene marker for AERD. ( An, S; Kim, YJ; Oh, T; Park, CS; Park, JS; Shin, S, 2012) |
| "SPINK5 single-nucleotide polymorphisms (SNPs) and SPINK5 expression levels were correlated with CRS without (CRSsNP) and with nasal polyps (CRSwNP), aspirin intolerance, asthma, and allergies." | 3.78 | Low SPINK5 expression in chronic rhinosinusitis. ( Brieger, J; Fruth, K; Goebel, G; Gosepath, J; Koutsimpelas, D; Mann, WJ; Schmidtmann, I, 2012) |
| "Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome associated with chronic inflammation in the airways coincident with chronic rhinitis, sinusitis, recurrent polyposis and asthma." | 3.78 | Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease. ( Jin, HJ; Kim, SH; Park, HS; Song, YS; Yang, EM, 2012) |
| "Chronic rhinosinusitis (CRS) with nasal polyposis (NP) may be associated with hypersensitivity to nonsteroidal anti-inflammatory drugs, representing a syndrome of aspirin-exacerbated respiratory disease (AERD)." | 3.78 | Incidence of aspirin hypersensitivity in patients with chronic rhinosinusitis and diagnostic value of urinary leukotriene E4. ( Celejewska-Wójcik, N; Cybulska, A; Hartwich, P; Hydzik-Sobocińska, K; Januszek, R; Mastalerz, L; Nieckarz, R; Oleś, K; Sanak, M; Stręk, P; Szaleniec, J; Wójcik, K, 2012) |
| "Aspirin is the most commonly used antiplatelet agent in patients with coronary artery disease (CAD)." | 3.78 | Aspirin sensitivity and coronary artery disease: implications for the practicing cardiologist. ( Das, P; Lieberman, P; Pattanaik, D, 2012) |
| "The aim of the present study was to develop a diagnostic set of single-nucleotide polymorphisms (SNPs) for discriminating aspirin-exacerbated respiratory disease (AERD) from aspirin-tolerant asthma (ATA) using the genome-wide association study (GWAS) data; the GWAS data were filtered according to p-values and odds ratios (ORs) using PLINK software, and the 10 candidate SNPs most closely associated with AERD were selected, based on 100 AERD and 100 ATA subjects." | 3.78 | A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study. ( Choi, BW; Choi, IS; Kim, MK; Kim, YJ; Park, BL; Park, CS; Park, J; Shin, H; Shin, SW; Uh, ST, 2012) |
| "Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin." | 3.77 | A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, IS; Hong, CS; Kim, JH; Kim, MK; Kim, Y; Koh, IS; Lee, JS; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| "In addition to the dysregulation of arachidonic acid metabolism in aspirin-intolerant asthma (AIA), aspirin acetylsalicylic acid (ASA) exerts effects on inflammation and immunity; however, many of these effects are unknown." | 3.77 | Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmatics. ( Byun, JY; Cheong, HS; Kim, MO; Lee, JY; Park, BL; Park, CS; Park, JS; Park, SM; Shin, HD, 2011) |
| "We sought to assess a vast platform of eicosanoids in different asthma phenotypes, including aspirin-intolerant asthma, by means of a recently developed analytic approach based on mass spectrometry." | 3.77 | Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype. ( Bochenek, G; Gielicz, A; Kaszuba, M; Niżankowska-Mogilnicka, E; Sanak, M; Szczeklik, A, 2011) |
| "Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of nasal polyps (NPs) and aspirin-intolerant asthma (AIA)." | 3.77 | Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthma. ( Alobid, I; Garcia-Garcia, FJ; Mullol, J; Pereda, J; Perez-Gonzalez, M; Picado, C; Pujols, L; Roca-Ferrer, J, 2011) |
| "Logistic regression analysis of RGS7BP gene polymorphisms in patients with AERD (n = 102) and aspirin-tolerant asthma (n = 429) revealed that a haplotype of block 3 consisting of rare alleles +98092 C>G, +98853 C>T, and +104450 T>G of the RGS7BP gene was associated with AERD." | 3.77 | Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients. ( Cho, SH; Choi, BW; Choi, IS; Hong, CS; Kim, MK; Lee, EH; Lee, JY; Lee, SH; Park, BL; Park, CS; Park, JS; Park, SM; Park, SW; Shin, HD; Uh, ST, 2011) |
| "OBJECTIVES/PROBLEM: To determine the sinonasal effect of aspirin salicylic acid (ASA) desensitization in patients with nasal polyps, asthma and aspirin intolerance (ASA triad)." | 3.77 | Aspirin desensitization for ASA triad patients--prospective study of the rhinologist`s perspective. ( Forer, B; Kivity, S; Landsberg, R; Sade, J, 2011) |
| " In this study we aimed to analyze the epigenetic patterns, in terms of DNA methylation, of three well-characterized populations of house dust mite allergic subjects, aspirin-intolerant asthmatics and controls." | 3.77 | Epigenetic changes in B lymphocytes associated with house dust mite allergic asthma. ( Dávila, I; Greally, JM; Isidoro-Garcia, M; Lorente, F; Padrón, J; Pascual, M; Suzuki, M; Turner, T, 2011) |
| "The present study inluded 22 patients presenting either with very severe or moderately severe aspirin triad 17 of whom suffered exacerbation of chronic polypous suppurative rhinosinusitis." | 3.77 | [The treatment of polypous suppurative rhinosinusitis in the patients presenting with the severe and moderate aspirin triad]. ( Riabova, MA; Shumilova, NA, 2011) |
| "Theophylline is commonly used to treat severe asthma and chronic obstructive pulmonary disease (COPD) characterized by non-eosinophilic inflammation." | 3.76 | Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma. ( Choi, DS; Choi, JP; Gho, YS; Jeon, SG; Kim, YK; Kim, YS; Moon, HG; Yoon, CM, 2010) |
| "We present a 19-month-old boy with a history of asthma who presented to the pediatric emergency department with noisy breathing and tachypnea partially responsive to albuterol." | 3.76 | A 19-month-old boy with recurrent respiratory distress. ( Cross, KP; Herr, SM; Randell, KA, 2010) |
| " Aspirin-intolerant asthma and anaphylaxis accompany PGD(2) overproduction, possibly associated with mast cell activation via the COX pathway." | 3.76 | Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers. ( Akiyama, K; Fukutomi, Y; Higashi, N; Kajiwara, K; Mita, H; Ono, E; Sekiya, K; Taniguchi, M; Tanimoto, H; Yamaguchi, H, 2010) |
| "These findings suggest that ASA changes Th17-type into Th2-type inflammation mainly via the adenosine and uric acid metabolic pathway in the lung." | 3.76 | Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung. ( Gyu Jeon, S; Kim, YK; Kim, YS; Moon, HG; Oh, SY; Song Gho, Y; Tae, YM; Zhu, Z, 2010) |
| "According to the GA2LEN recommendations, nasal challenge test with lysine-aspirin should be performed only in patients with severe asthma, because the sensitivity of this test has been lower than in bronchial and oral challenge tests." | 3.76 | Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis. ( Dahlén, B; Ehnhage, A; Juto, JE; Kölbeck, KG; Stjärne, P, 2010) |
| "Aspirin-intolerant asthma (AIA) is characterized by severe asthmatic attack after ingestion of aspirin and/or non-steroidal anti-inflammatory drugs." | 3.76 | Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics. ( Cho, SH; Choi, BW; Choi, IS; Choi, JS; Hong, CS; Kim, MK; Kim, YH; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, JS; Park, SM; Shin, HD; Uh, ST, 2010) |
| "Aspirin-intolerant asthma (AIA) occurs from asthma exacerbation after exposure to aspirin." | 3.76 | Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Chun, JY; Kim, JH; Kim, MK; Kim, Y; Kim, YH; Lee, JS; Park, BL; Park, CS; Park, JS; Park, TJ; Pasaje, CF; Shin, HD; Uh, ST; Yoon, SH, 2010) |
| " Thus, functional alterations of the NAT gene may contribute to the risk of aspirin-intolerant asthma." | 3.76 | Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics. ( Chang, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jung, S; Kim, JM; Kim, MK; Kim, MO; Kim, YH; Lee, EH; Lee, SH; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST, 2010) |
| "Many patients with aspirin-induced asthma have severe methacholine airway hyperresponsiveness (AHR), suggesting a relationship between aspirin and methacholine in airway response." | 3.76 | Airway responsiveness to inhaled aspirin is influenced by airway hyperresponsiveness in asthmatic patients. ( Choi, IS; Han, ER; Kim, CS; Kim, DE; Kim, S; Kim, YJ; Park, DJ, 2010) |
| "There is a well-recognized association of aspirin sensitivity, aspirin-induced asthma, nasal polyposis or sinusitis, known as Samter's triad." | 3.76 | Aspirin sensitivity and the nose. ( Douglas, GC; Karkos, PD; Swift, AC, 2010) |
| "Aspirin affects interleukin-4 (IL-4) synthesis; however, the genetic role of IL-4 has not been evaluated in asthmatics with aspirin hypersensitivity." | 3.76 | Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity. ( Cho, SH; Choi, BW; Choi, IS; Chung, IY; Hong, CS; Jang, AS; Kang, JH; Kim, BS; Kim, MK; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST; Uhm, TG, 2010) |
| "Aspirin-intolerant asthma (AIA) is a rare condition that is characterized by the development of bronchoconstriction in asthmatic patients after ingestion of non-steroidal anti-inflammatory drugs including aspirin." | 3.76 | Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jang, AS; Kim, JH; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Shin, HD; Uh, ST, 2010) |
| "It was the aim of this study to investigate the prevalence of otologic manifestations in a cohort of Samter's syndrome patients (nasal polyps with chronic rhinosinusitis, aspirin intolerance and asthma)." | 3.75 | Otologic manifestations in Samter's syndrome. ( Caversaccio, M; Häusler, R; Helbling, A, 2009) |
| "Patients with aspirin-sensitive asthma and/or nasal polyps (n = 40), patients with aspirin-tolerant asthma and/or nasal polyps (n = 13) and healthy volunteers (n = 26) were included." | 3.75 | Cellular allergen stimulation test with acetylsalicylic acid-lysine is not a useful test to discriminate between asthmatic patients with and without acetylsalicylic acid sensitivity. ( Bavbek, S; Birben, E; Dursun, AB; Kalayci, O; Misirligil, Z, 2009) |
| "Nasal polyps are characterized by eosinophilic infiltration, and frequently coexist with asthma, aspirin intolerance and allergy." | 3.75 | Clinical significance of eosinophilic cationic protein levels in nasal secretions of patients with nasal polyposis. ( Auo, HJ; Joo, YH; Kang, JM; Sun, DI, 2009) |
| "Among the patients with asthma, polymorphism at -1082A/G was significantly associated with the phenotype of aspirin-intolerant asthma, AIA (P = 0." | 3.75 | Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. ( Cho, BY; Kim, SH; Lee, HN; Park, HS; Yang, EM; Ye, YM, 2009) |
| "Airway eosinophilia is a hallmark of aspirin-sensitive asthma/rhinitis." | 3.75 | Chemokine CC-ligand 5 production and eosinophil activation into the upper airways of aspirin-sensitive patients. ( Fuentes-Beltrán, A; García-Cruz, Mde L; Montes-Vizuet, R; Negrete-García, MC; Teran, LM; Valencia-Maqueda, E, 2009) |
| " Enzyme up-regulation was monitored after in vitro stimulation with lipopolysaccharide (LPS) and/or aspirin in 19 aspirin-intolerant (AI) patients (8 aspirin-sensitive asthmatics and 11 urticaria-angioedema patients) and 14 healthy controls." | 3.75 | Aspirin-induced COX-2 overexpression in monocytes of aspirin-intolerant patients. ( Bajrovic, N; Korosec, P; Kosnik, M; Morgan, T; Silar, M, 2009) |
| "Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp)." | 3.75 | Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma. ( Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Kurono, Y; Matsune, S; Sano, Y; Sekigawa, T; Tajima, A, 2009) |
| "Aspirin-exacerbated respiratory disease is characterized by asthma, nasal polyps, and intolerance to aspirin with overexpression of leukotriene (LT) C(4) synthase and cysteinyl leukotriene receptors." | 3.75 | Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization. ( Borish, L; Culp, JA; Kropf, E; Steinke, JW, 2009) |
| "We previously demonstrated that single nucleotide polymorphism (SNP) and haplotypes were associated with aspirin hypersensitivity in asthmatics." | 3.75 | Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. ( Chang, HS; Choi, IS; Chung, IY; Il Lim, G; Jang, AS; Kim, MK; Park, BL; Park, CS; Park, JS; Park, SM; Park, SW; Rhim, T; Shin, HD; Shin, JA; Uh, ST, 2009) |
| "Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks." | 3.74 | Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008) |
| " Often it is associated with non allergic rhinitis with eosinophilia syndrome (NARES), nasal polyposis and intolerance to Aspirin and NSAID's." | 3.74 | [Nonallergic diseases of the upper and lower airways]. ( Menz, G; Rothe, T, 2008) |
| " We hypothesized that the three subsets of the FCER1 gene may play a role in the development of the aspirin-intolerant asthma (AIA) phenotype and analyzed these genetic polymorphisms in association with clinical parameters in AIA patients." | 3.74 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma. ( Cho, BY; Hur, GY; Kim, SH; Palikhe, NS; Park, HS; Ye, YM, 2008) |
| "Aspirin provocation tests were performed in 667 asthmatic patients and changes in FEV(1) were used to categorize patients as ATA or AIA." | 3.74 | Obesity in aspirin-tolerant and aspirin-intolerant asthmatics. ( Jang, AS; Kim, DJ; Kim, YH; Park, CS; Park, HS; Park, JS; Park, SW; Seo, KH; Uh, ST, 2008) |
| "Aspirin-intolerant asthma (AIA) refers to the development of bronchoconstriction in asthmatic individuals following the ingestion of aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.74 | Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. ( Chang, HS; Cho, SH; Choi, IS; Chung, IY; Kim, MK; Kim, TH; Nam, BY; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Rhim, T; Shin, HD, 2008) |
| " Clinical data show that mixed COX-1/COX-2 inhibitors such as aspirin, but not COX-2 selective inhibitors such as rofecoxib, induce bronchoconstriction and asthma in sensitive individuals." | 3.74 | COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma. ( Harrington, LS; Lucas, R; McMaster, SK; Mitchell, JA; Moreno, L; Scadding, G; Warner, TD, 2008) |
| "Platelets are involved in the pathogenesis of aspirin-induced asthma (AIA)." | 3.74 | Selenium status in patients with aspirin-induced asthma. ( Hassan, AM, 2008) |
| "A diagnosis of aspirin-intolerant asthma requires aspirin provocation in specialist clinics." | 3.74 | Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma. ( Daham, K; Dahlén, B; Dahlén, SE; Delin, I; Gaber, F; Gülich, A; Gyllfors, P; Higashi, A; Higashi, N; James, A; Kumlin, M; Nord, M; Skedinger, M, 2008) |
| " In these cases, CRS tends to be associated with bronchial asthma (BA), especially, aspirin-intolerant asthma (AIA)." | 3.74 | Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma. ( Haruna, S; Moriyama, H; Otori, N; Yoshikawa, M; Yoshimura, T, 2008) |
| "Rhinosinusitis is highly associated with aspirin-intolerant asthma (AIA)." | 3.74 | Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients. ( Holloway, JW; Kim, SH; Park, CS; Park, HS; Shin, HD, 2007) |
| "In an observational cohort study, women who self-selected for frequent aspirin use developed less newly diagnosed asthma than women who did not take aspirin." | 3.74 | Aspirin and decreased adult-onset asthma: randomized comparisons from the physicians' health study. ( Barr, RG; Buring, JE; Gaziano, JM; Hennekens, CH; Kurth, T; Stampfer, MJ, 2007) |
| "Aspirin desensitization is indicated for patients who have aspirin-exacerbated respiratory disease and whose asthma and/or rhinosinusitis is suboptimally controlled with inhaled corticosteroids and leukotriene-modifying drugs." | 3.74 | Aspirin challenge and desensitization for aspirin-exacerbated respiratory disease: a practice paper. ( Bernstein, JA; Castells, MC; Gawchik, SM; Lee, TH; Macy, E; Settipane, RA; Simon, RA; Wald, J; Woessner, KM, 2007) |
| "Of 147 patients who reported seeking acute medical care for their historical aspirin/NSAID-induced asthma attacks, 101 (69%) were treated in an emergency department and released, and 46 (31%) required hospitalization." | 3.74 | The relationship between historical aspirin-induced asthma and severity of asthma induced during oral aspirin challenges. ( Simon, RA; Stevenson, DD; Williams, AN; Woessner, KM, 2007) |
| "Genetic predisposition is linked to the pathogenesis of aspirin-intolerant asthma." | 3.74 | Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma. ( Bahn, JW; Chang, YS; Jee, YK; Kim, SH; Kim, YK; Lee, JE; Min, KU; Park, HS; Park, HW; Shin, ES; Ye, YM, 2007) |
| "The study included 30 patients with ASA, 30 patients with aspirin-tolerant asthma (ATA) and 30 HS serving as controls." | 3.74 | Alternative splicing of cyclooxygenase-1 gene: altered expression in leucocytes from patients with bronchial asthma and association with aspirin-induced 15-HETE release. ( Borowiec, M; Kowalski, ML; Kurowski, M; Pawliczak, R, 2007) |
| " There was a significant increase in aspirin intolerant asthma (AIA, 25." | 3.74 | Analysis of perimenstrual asthma based on questionnaire surveys in Japan. ( Akazawa, K; Arakawa, M; Gejyo, F; Hasegawa, T; Koya, T; Sakagami, T; Suzuki, E; Suzuki, K; Toyabe, S, 2007) |
| " Analysis of bronchial biopsies and bronchial epithelial cells in culture conducted so far gave conflicting results of expression pattern of these enzymes in healthy subjects and asthmatics patients, with and without aspirin hypersensitivity." | 3.74 | Deficiency of cyclooxygenases transcripts in cultured primary bronchial epithelial cells of aspirin-sensitive asthmatics. ( Nizankowska-Mogielnicka, E; Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A; Woś, M, 2007) |
| "Aspirin induced asthma (AIA) is a syndrome characterised by intolerance to acetylsalycilic acid (ASA), nasal polyps and bronchial asthma, being the metabolic shift of arachidonic acid toward the lipoxygenase pathway and hyper-production of cysteinyl-leukotrienes (cys-LTs) the current pathogenetic hypothesis." | 3.74 | Urinary LTE4 is higher after nasal provocation test with L-ASA in bronchial than in only nasal responders. ( Dal Negro, RW; Micheletto, C; Tognella, S; Trevisan, F; Visconti, M, 2007) |
| "In this study, we compared the roles of CysLT receptor type 1 (CysLTR1) and leukotriene C4 synthase (LTC4S) gene polymorphisms in two major aspirin-related allergic diseases, aspirin-intolerant asthma (AIA) and aspirin-induced chronic urticaria/angioedema (AICU)." | 3.74 | Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity. ( Kim, SH; Lee, HY; Park, HJ; Park, HS; Yang, EM; Ye, YM, 2007) |
| "We conducted a retrospective study to determine the prevalence of Samter's triad (nasal polyps, asthma, and aspirin sensitivity) in 208 consecutively presenting patients who had undergone functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis from September 2001 through August 2003." | 3.74 | The prevalence of Samter's triad in patients undergoing functional endoscopic sinus surgery. ( Kim, JE; Kountakis, SE, 2007) |
| "The study groups consisted of 22 subjects with AERD, 22 subjects with ATA and 10 volunteers without asthma and aspirin sensitivity." | 3.74 | Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity. ( Celik, GE; Erkekol, FO; Melli, M; Misirligil, Z, 2007) |
| "Leukotriene receptor antagonists (LTRA), such as montelukast, have been used as a first-line treatment for patients with aspirin-intolerant asthma (AIA)." | 3.74 | CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients. ( Hur, GY; Kim, SH; Lee, HY; Lee, SK; Park, HS; Sampson, AP; Ye, YM, 2007) |
| "In aspirin-sensitive patients with asthma, bronchial obstruction induced by oral aspirin may be associated with extrabronchial symptoms, suggesting the systemic character of the response." | 3.74 | Systemic responses after bronchial aspirin challenge in sensitive patients with asthma. ( Bienkiewicz, B; Grzegorczyk, J; Kowalski, ML; Makowska, JS; Wozniak, M, 2008) |
| "The aim of the investigation was to study melatonin production in thrombocytes and their functional activity in correlation with 6-sulfatoximelatonin (6-SOM) urinary excretion in patients with aspirin-induced bronchial asthma (AIBA)." | 3.74 | [Melatonin production in thrombocytes and their functional activity in patients with aspirin asthma]. ( Evsiukova, EV; Kveshnoĭ, IM; Muraia, EV; Zubzhitskaia, LB, 2007) |
| "Aspirin-intolerant asthma (AIA), a major clinical presentation of aspirin hypersensitivity, affects 10% of adult asthmatics." | 3.74 | Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics. ( Cho, BY; Jeong, HH; Kim, M; Kim, SH; Lee, HY; Lee, J; Park, HS; Wee, K, 2008) |
| "To identify genes whose expression is most characteristic of chronic rhinosinusitis and aspirin-sensitive asthma through genome-wide transcriptional profiling of nasal polyp tissue." | 3.74 | Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma. ( Goldsztein, H; Metson, R; Platt, MP; Reh, DD; Stankovic, KM, 2008) |
| "The mechanism of aspirin (acetylsalicylic acid: ASA) hypersensitivity in asthmatic patients is related to arachidonic acid metabolism abnormalities, and specific triggering by ASA of 15-hydroxyeicosatetraenoic acid (15-HETE) generation was observed in leucocytes from aspirin-sensitive (AS) but not from aspirin-tolerant (AT) asthmatics." | 3.74 | Involvement of 15-lipoxygenase and prostaglandin EP receptors in aspirin-triggered 15-hydroxyeicosatetraenoic acid generation in aspirin-sensitive asthmatics. ( Bienkiewicz, B; Jedrzejczak-Czechowicz, M; Kowalski, ML; Lewandowska-Polak, A, 2008) |
| "Aspirin-sensitivity, asthma, and nasal polyposis (NP) comprise the clinical entity of Samter's triad." | 3.74 | Sinonasal outcomes after endoscopic sinus surgery in asthmatic patients with nasal polyps: a difference between aspirin-tolerant and aspirin-induced asthma? ( Awad, OG; Fasano, MB; Graham, SM; Lee, JH, 2008) |
| "To evaluate the frequencies of COX-2 SNPs in an Australian Caucasian population, and determine potential associations between common COX-2 promoter SNPs and asthma, asthma severity and aspirin-intolerant asthma (AIA)." | 3.74 | Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthma. ( Duffy, DL; Horn, J; Kedda, MA; Misso, NL; Shi, J; Thompson, PJ; Welch, MD; Williams, C, 2008) |
| "We recently found that paracetamol (acetaminophen) use in late pregnancy was associated with an increased risk of early wheezing in the offspring." | 3.73 | Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. ( Headley, JE; Henderson, AJ; Jones, RW; Newson, RB; Shaheen, SO; Strachan, DP; Stratton, FD, 2005) |
| "Widal disease is characterized by symptomatic triad of aspirin intolerance, nasal polyposis and asthma." | 3.73 | [Widal triad (Asthma-Nasal polyposis-aspirin intolerance): an inflammatory metabolism abnormality]. ( Leimgruber, A, 2005) |
| " Nasal polyp tissues were obtained from 29 patients [including nine with aspirin (ASA)-hypersensitivity and 12 with bronchial asthma] undergoing polypectomy for nasal obstruction." | 3.73 | Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma. ( Danilewicz, M; Jankowski, A; Kowalski, ML; Lewandowska-Polak, A; Pawliczak, R; Ptasińska, A; Wagrowska-Danilewicz, M; Woźniak, J, 2005) |
| "5-Lipooxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) are known as key enzymes in cysteinyl-leukotriene (cys-LT) production, critical mediators in aspirin acetylsalicyclic acid (ASA)-intolerant asthma (AIA)." | 3.73 | Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness. ( Bae, JS; Holloway, JW; Kim, SH; Nahm, DH; Park, HS; Suh, CH, 2005) |
| "Aspirin-sensitive asthma, aspirin-intolerant asthma, aspirin- (or non-steroidal anti-inflammatory drug [NSAID]) exacerbated respiratory disease are terms for a disorder commonly described as affecting adults aged > 30y." | 3.73 | A teenager with severe asthma exacerbation following ibuprofen. ( Palmer, GM, 2005) |
| "1 encodes a receptor for CYSLTs, potent biological mediators in the pathogenesis of asthma, particularly that associated with aspirin intolerance (AIA)." | 3.73 | Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics. ( Chang, HS; Choi, JH; Choi, YH; Kim, LH; Lee, JH; Lee, YM; Park, BL; Park, CS; Park, HS; Park, JS; Shin, HD, 2005) |
| "Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not." | 3.73 | Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005) |
| "To investigate the impact of nasal polyps on quality of life compared with the Spanish general population using the SF-36 questionnaire; and to evaluate the impact of asthma and aspirin sensitivity on quality of life in patients with nasal polyposis." | 3.73 | The impact of asthma and aspirin sensitivity on quality of life of patients with nasal polyposis. ( Alobid, I; Benítez, P; Bernal-Sprekelsen, M; Guilemany, JM; Mullol, J; Picado, C, 2005) |
| "We have previously demonstrated that aspirin triggers specific generation of 15-hydroxyeicosateraenoic acid (15-HETE) from nasal polyp epithelial cells and peripheral blood leukocytes (PBL) from aspirin-sensitive (AS) but not aspirin-tolerant (AT) patients with asthma/rhinosinusitis." | 3.73 | Aspirin-triggered 15-HETE generation in peripheral blood leukocytes is a specific and sensitive Aspirin-Sensitive Patients Identification Test (ASPITest). ( Bienkiewicz, B; Cieslak, M; Dubuske, L; Grzegorczyk, J; Jedrzejczak, M; Kowalski, ML; Pawliczak, R; Ptasinska, A, 2005) |
| " Multiple regression analysis confirmed that aspirin-intolerant asthma (AIA) was strongly associated with NFA." | 3.73 | Contribution of aspirin-intolerant asthma to near fatal asthma based on a questionnaire survey in Niigata Prefecture, Japan. ( Arakawa, M; Gejyo, F; Hasegawa, T; Kondoh, A; Koya, T; Suzuki, E; Terada, M; Yoshimine, F; Yoshizawa, H, 2005) |
| "We sought to investigate the role of aspirin-exacerbated respiratory disease (AERD) as a risk factor for the development of irreversible airway obstruction." | 3.73 | Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma. ( Bleecker, ER; Borish, L; Deniz, YM; Haselkorn, T; Mascia, K; Miller, DP, 2005) |
| "The blocking effect of controller medications for asthma could have an effect on the outcome of aspirin challenges in patients suspected of having aspirin-exacerbated respiratory disease (AERD)." | 3.73 | The blocking effect of essential controller medications during aspirin challenges in patients with aspirin-exacerbated respiratory disease. ( Simon, RA; Stevenson, DD; White, AA, 2005) |
| "Aspirin-induced asthma (AIA) is a distinct clinical syndrome that affects up to 10% of adults with asthma." | 3.73 | Complement C3a and C4a increased in plasma of patients with aspirin-induced asthma. ( Cho, SY; Choi, YS; Kim, SH; Lee, SH; Min, JW; Paik, YK; Park, CS; Rhim, T, 2006) |
| "GSTP1 Ile105Val polymorphism was determined using a single based extension method in 88 AIA subjects and compared to 154 aspirin-tolerant asthma (ATA) subjects and 119 normal healthy controls (NC) recruited from the Korean population." | 3.73 | Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma. ( Kim, SH; Lee, JH; Lee, YM; Nahm, DH; Oh, JM; Park, CS; Park, HS; Shin, HD; Suh, CH, 2005) |
| "Eosinophilic infiltration of airway tissue is a central feature of aspirin-induced asthma (AIA)." | 3.73 | Comparison of plasma eotaxin family level in aspirin-induced and aspirin-tolerant asthma patients. ( Jang, AS; Lee, JH; Lee, SH; Min, JW; Park, CS; Park, SM; Park, SW, 2005) |
| "Aspirin-intolerant asthma (AIA) is a distinct clinical syndrome that refers to the development of bronchoconstriction in asthmatic individuals following the ingestion of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)." | 3.73 | Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population. ( Bae, JS; Choi, JH; Kim, SH; Nahm, DH; Park, HS; Suh, CH; Yu, HL, 2006) |
| "2%); A-polyps and bronchial asthma without aspirin intolerance (n = 19-28." | 3.73 | [Nasal polyps is not a homogenous pathology]. ( Arcimowicz, M; Balcerzak, J; Samoliński, BK, 2005) |
| "The pathogenesis of aspirin (acetylsalicylic acid, ASA)-intolerant urticaria (AIU) is still poorly understood but it has recently been suggested that it is associated with the overproduction of leukotriene (LT)." | 3.73 | Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population. ( Choi, JH; Ha, EH; Holloway, JW; Kim, SH; Nahm, DH; Park, CS; Park, HS; Suh, CH, 2005) |
| "Hypersensitivity to aspirin usually takes the form of a clinical syndrome combining chronic rhinitis, nasal polyposis and asthma attacks that are exacerbated by aspirin or other non steroidal anti-inflammatory drugs (NSAIDs)." | 3.73 | [New pathophysiological concepts on aspirin hypersensitivity (Widal syndrome); diagnostic and therapeutic consequences]. ( de Weck, A; Gamboa, P; Sanz, ML, 2005) |
| " Urinary leukotriene E4 concentration (LTE4), that reflects the whole body production of cysteinil-leukotrienes, is particularly increased in patients with aspirin-intolerant asthma (AIA)." | 3.73 | Aspirin induced asthma (AIA) with nasal polyps has the highest basal LTE4 excretion: a study vs AIA without polyps, mild topic asthma, and normal controls. ( Dal Negro, RW; Facchini, FM; Micheletto, C; Tognella, S; Visconti, M, 2006) |
| " CysLTR1-selective antagonists have anti-bronchoconstrictive and anti-inflammatory effects in asthma, particularly aspirin-intolerant asthma (AIA)." | 3.73 | Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males. ( Kim, SH; Kim, YS; Nahm, DH; Oh, JM; Palmer, LJ; Park, HS; Suh, CH, 2006) |
| "Aspirin-induced asthma (AIA) is a syndrome characterized by intolerance to aspirin (ASA), nasal polyps and bronchial asthma, the metabolic shift of arachidonic acid towards the lipoxygenase pathway and hyper-production of cysteinyl-leukotrienes (cys-LTs) being the current pathogenetic hypothesis." | 3.73 | Changes in urinary LTE4 and nasal functions following nasal provocation test with ASA in ASA-tolerant and -intolerant asthmatics. ( Dal Negro, RW; Micheletto, C; Tognella, S; Trevisan, F; Visconti, M, 2006) |
| "Several studies have suggested the involvement of an autoimmune mechanism in aspirin (ASA)-intolerant asthma." | 3.73 | Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation. ( Choi, JH; Kim, SH; Nahm, DH; Park, HS; Suh, CH; Ye, YM, 2006) |
| "We speculated TNF-alpha can be one of candidate gene for aspirin-intolerant asthma (AIA) because TNF-alpha is pro-inflammatory cytokine and known to be increased level in asthmatic airways." | 3.73 | Association of TNF-alpha genetic polymorphism with HLA DPB1*0301. ( Choi, JH; Holloway, JW; Kim, SH; Lee, SK; Park, CS; Park, HS; Ye, YM, 2006) |
| "By the first 6 months of aspirin treatment, there were significant reductions in sinus infections and numbers of short courses of prednisone and improvements in sense of smell and general assessment of nasal-sinus and asthma symptoms (P <." | 3.72 | Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. ( Berges-Gimeno, MP; Simon, RA; Stevenson, DD, 2003) |
| "To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level using the automated fluorometric analyzer were observed in 13 aspirin (ASA)-sensitive asthma subjects (group I: 7 early responders and group II: 6 dual responders) during lysine aspirin bronchoprovocation test (L-ASA BPT)." | 3.72 | Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients. ( Kim, SS; Lee, SK; Lee, YM; Nahm, DH; Park, HS; Yoon, HJ, 2003) |
| "We examined whether a decreased activity of nuclear factor(NF)-kappaB), a transcriptional regulator of cyclooxygenase-2 (COX-2), could account for down-regulation of COX-2 in nasal polyps of aspirin-sensitive asthmatics." | 3.72 | Nuclear factor-kappaB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics. ( Benitez, P; Bioque, G; Bulbena, O; Mullol, J; Picado, C; Pujols, L; Roca-Ferrer, J, 2003) |
| "We sought to determine blood and urinary levels of 9alpha,11beta-PGF(2), a major stable PGD(2) metabolite in 2 well-defined phenotypes of asthma, aspirin-induced asthma (AIA) and aspirin-tolerant asthma (ATA), and in healthy control subjects and to study the effects of aspirin on PGD(2) release." | 3.72 | A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. ( Bochenek, G; Nagraba, K; Nizankowska, E; Szczeklik, A, 2003) |
| "The use of analgesic anti-inflammatory agents in patients with asthma is clinically challenging because of the prevalence (10-20%) of aspirin hypersensitivity." | 3.72 | COX-2: Where are we in 2003? - Specific cyclooxygenase-2 inhibitors and aspirin-exacerbated respiratory disease. ( Crofford, LJ, 2003) |
| " The cells were isolated from 3 groups of subjects: nonasthmatic patients (n = 10), patients with aspirin-tolerant asthma (ATA, n = 9), and patients with aspirin-intolerant asthma (AIA, n = 7)." | 3.72 | Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. ( Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A, 2003) |
| "In 5-10% of adult patients with asthma, aspirin and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks." | 3.72 | Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Martín-García, C, 2003) |
| "Aspirin and other inhibitors of cyclo-oxygenase precipitate acute bronchospasm in about 10% of adult asthmatics." | 3.72 | Glutathione peroxidase activity in blood cells from aspirin-induced asthma patients. ( Hassan, AM, 2003) |
| "Although the mechanisms of aspirin-induced rhinosinusitis-asthma appear to be related to arachidonic acid abnormalities, only recently has a specific aspirin-triggered enhancement of 15-hydroxyeicosatetraenoic acid (15-HETE) generation in nasal polyp epithelial cells from aspirin-sensitive patients been demonstrated." | 3.72 | Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. ( Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A, 2003) |
| "We report the case of a 60 year old woman, suffering for 8 years from aspirin-induced asthma, having an airway infection of RSV-respiratory syncytial virus." | 3.72 | [Exacerbation of aspirin-induced asthma associated with RSV infection]. ( Filipowicz, E; Sanak, M, 2003) |
| " Aspirin-induced asthma (AIA) is a typical drug-induced phenotype due to aspirin or nonsteroidal antiinflammatory drugs, and these drugs are metabolized by CYP2C9 and UGT1A6, which are regulated by PXR." | 3.72 | Characterization of six base pair deletion in the putative HNF1-binding site of human PXR promoter. ( Hasegawa, T; Hasegawa, Y; Inoue, I; Koshino, T; Sakamoto, Y; Uno, Y; Yoshida, K, 2003) |
| "Polyposis, asthma, aspirin-intolerance and aspirin-triad are mostly accompanied with eosinophilia of mucosal airways." | 3.72 | RANTES, eotaxin and eotaxin-2 expression and production in patients with aspirin triad. ( Maune, S; Pods, R; Ross, D; Rudack, C; van Hülst, S, 2003) |
| "It is unclear whether subclinical airway responses to aspirin occur in subjects with nasal polyps and/or asthma without overt sensitivity." | 3.72 | Subclinical aspirin sensitivity in subjects with nasal polyposis. ( Gibson, GJ; Killen, JW; Wilson, JA, 2003) |
| "In group of patients with aspirin asthma basic concentration of LTE4 was 416." | 3.72 | [Urinary leukotriene E4 concentration in patients with bronchial asthma and intolerance of non-steroids anti-inflammatory drugs before and after oral aspirin challenge]. ( Chazan, R; Rubinsztajn, R; Wrońska, J, 2003) |
| "The urinary leukotriene E4 (U-LTE4) concentration is significantly increased in patients with aspirin-intolerant asthma (AIA)." | 3.72 | Clinical features of asthmatic patients with increased urinary leukotriene E4 excretion (hyperleukotrienuria): Involvement of chronic hyperplastic rhinosinusitis with nasal polyposis. ( Akiyama, K; Higashi, A; Higashi, N; Ishii, T; Kawagishi, Y; Mita, H; Osame, M; Taniguchi, M, 2004) |
| "The data from this study show that aspirin intolerance, HDM allergy, and asthma duration exceeding 10 years are major factors associated with severe asthma in outpatients." | 3.72 | Aspirin intolerance and allergy to house dust mites: important factors associated with development of severe asthma. ( Górski, P; Kuna, P; Kupczyk, M; Kupryś, I, 2004) |
| "We sought to screen the LTC(4) synthase gene for polymorphisms and to determine whether there is an association between these polymorphisms and asthma severity or aspirin sensitivity in a large, well-phenotyped population and to determine whether this polymorphism is functionally relevant." | 3.72 | Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. ( Duffy, D; Fong, K; Kedda, MA; O'Hara, K; Phelps, S; Shi, J; Thompson, PJ; Yang, I, 2004) |
| "Aspirin challenge of aspirin-intolerant asthma (AIA) patients causes a significant increase in leukotriene E4 (LTE4) concentration in urine." | 3.72 | Increase in urinary leukotriene B4 glucuronide concentration in patients with aspirin-intolerant asthma after intravenous aspirin challenge. ( Akiyama, K; Higashi, A; Higashi, N; Mita, H; Taniguchi, M, 2004) |
| "Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those with aspirin-intolerant asthma (AIA) than aspirin-tolerant asthma (ATA)." | 3.72 | Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma. ( Kim, HJ; Kim, SH; Nahm, DH; Park, HS; Sampson, AP; Suh, CH; Suh, YJ; Yoon, SH, 2004) |
| " Although the latter is conventionally used in nasal lysine-aspirin challenge, use of the former in aspirin-induced asthma (AIA) has never been evaluated." | 3.72 | Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma. ( Haggart, K; Lee, DK; Lipworth, BJ, 2004) |
| "Nasal polyps were obtained from 16 aspirin-tolerant patients with asthma/rhinitis (ATAR) and 18 aspirin-intolerant patients with asthma/rhinitis (AIAR) undergoing nasal polypectomy." | 3.72 | Dynamics of COX-2 in nasal mucosa and nasal polyps from aspirin-tolerant and aspirin-intolerant patients with asthma. ( Alobid, I; Mullol, J; Picado, C; Pujols, L; Roca-Ferrer, J; Xaubet, A, 2004) |
| "Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.72 | Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach. ( Goto, S; Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Jinnai, N; Kakihara, M; Koshino, T; Nakajima, T; Sakagami, T; Sano, Y; Sekigawa, T; Suzuki, N; Yoshida, K, 2004) |
| " We hypothesized that this polymorphism, which may result in decreased COX-2 transcription, could be associated with more severe asthma, and/or aspirin-intolerant asthma (AIA)." | 3.72 | A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population. ( Duffy, DL; Kedda, MA; Misso, NL; Shi, J; Thompson, PJ, 2004) |
| "We wondered whether application of expiratory breath condensate could facilitate diagnosis of aspirin-intolerant asthma and reproduce eicosanoids mediators' abnormalities described in this disease." | 3.72 | Exhaled eicosanoids following oral aspirin challenge in asthmatic patients. ( Bochenek, G; Kiełbasa, B; Sanak, M; Szczeklik, A, 2004) |
| "Aspirin-induced asthma and rhinitis (AIAR) appear to be precipitated by the inhibition of cyclo-oxygenase (COX)." | 3.71 | Aspirin-intolerant asthma: role of cyclo-oxygenase enzymes. ( Picado, C, 2002) |
| "The pathogenesis of aspirin-induced asthma (AIA) has not yet been clearly elucidated, although eicosanoid metabolites appear to play an important role." | 3.71 | Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma. ( Antczak, A; Barnes, PJ; Gorski, P; Kharitonov, S; Montuschi, P, 2002) |
| "Although many studies have assumed that the overproduction of cysteinyl- leukotrienes (cys-LTs) and an imbalance of arachidonic acid metabolism may be plausible causes for the pathogenesis of aspirin-intolerant asthma (AIA), there has been little experimental evidence to substantiate this notion in lower airways of patients with AIA." | 3.71 | A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. ( Akiyama, K; Higashi, N; Mita, H; Osame, M; Taniguchi, M, 2002) |
| "The full clinical picture of aspirin intolerance, Sampter's triad, is associated with nasal polyposis, clinical sensitivity to most non steroidal antiinflammatory drugs (NSAID) and intrinsic bronchial asthma." | 3.71 | [Aspirin sensitivity: long term follow-up after up to 3 years of adaptive desensitization using a maintenance dose of 100 mg of aspirin a day]. ( Gosepath, J; Mann, WJ; Schäfer, D, 2002) |
| "We recently reported links between frequent paracetamol (acetaminophen) use and wheezing and asthma in adults and children, but data are lacking on possible effects of prenatal exposure on wheezing in early childhood." | 3.71 | Paracetamol use in pregnancy and wheezing in early childhood. ( Burney, PG; Golding, J; Henderson, AJ; Heron, JE; Newson, RB; Shaheen, SO; Sherriff, A, 2002) |
| "Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinitis, nasal polyps, asthma, and precipitation of asthma and rhinitis attacks after ingestion of aspirin (ASA) and most nonsteroidal anti-inflammatory drugs (NSAIDs)." | 3.71 | The natural history and clinical characteristics of aspirin-exacerbated respiratory disease. ( Berges-Gimeno, MP; Simon, RA; Stevenson, DD, 2002) |
| " PAF activity correlated with tissue eosinophilia and polyps obtained from patients with aspirin-sensitive asthma contained relatively large amounts of PAF, with enriched infiltration of eosinophils." | 3.71 | Presence of platelet-activating factor in nasal polyps and eosinophils. ( Furukawa, M; Ogura, M; Tsuji, H; Tsutsumi, T; Yamashita, T, 2002) |
| "The effect of arachidonic acid or platelet agonists on LTC4 synthase activity was investigated in platelets obtained from healthy volunteers, aspirin-intolerant asthmatics or aspirin-tolerant asthmatics after in vivo treatment or in vitro pre-incubation with aspirin." | 3.71 | Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment. ( Edenius, C; Ehnhage, A; Kölbeck, KG; Lindgren, JA; Tornhamre, S, 2002) |
| "We describe the case of an aspirin-sensitive asthma patient with a history of anaphylactic reactions to nonsteroidal anti-inflammatory drugs." | 3.71 | Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma. ( Fischer, R; Harrell, K; Marks, F, 2001) |
| "Although it has been hypothesized that analgesic idiosyncrasy could be acquired by viral infection, there is no evidence that any virus can cause sporadic cases of aspirin-intolerant asthma." | 3.71 | Possible relevance of virus infection for development of analgesic idiosyncrasy. ( Akahori, K; Amayasu, H; Hasegawa, H; Nakabayashi, M; Nakagawa, H; Shoji, T; Yoshida, S, 2001) |
| " In patients with aspirin-induced asthma (AIA) bronchial biopsies revealed eosinophil infiltration and a marked increase in IL-5 positive cells." | 3.71 | Serum interleukin-5 in aspirin-induced asthma. ( Mastalerz, L; Sanak, M; Szczeklik, A, 2001) |
| "Aspirin inhibits cyclooxygenase activity and modifies production of the arachidonate cascade in aspirin-induced asthma." | 3.71 | Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients. ( Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, S, 2001) |
| "Nasal polyposis occurs frequently in patients with intrinsic asthma, especially in those who are aspirin sensitive." | 3.71 | An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma. ( Darby, YC; Parikh, A; Ragab, S; Scadding, GK, 2001) |
| "The decrease in prostaglandin E(2) (PGE(2)) release due to aspirin (ASA)-induced cyclooxygenase inhibition and the increment in cysteinyl leukotriene (Cys-LT) release secondary to the removal of the inhibitory effect of PGE(2) on Cys-LT release have been suggested in the pathogenesis of aspirin-induced asthma (AIA)." | 3.71 | Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients. ( Bavbek, S; Celik, G; Melli, M; Misirligil, Z, 2001) |
| " Aspirin-induced asthma tended to be severe." | 3.71 | Airway hyperresponsiveness and pulmonary function in adult asthma. ( Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T, 2001) |
| "Although there is increasing evidence of the importance of cysteinyl leukotrienes (LT) as mediators of aspirin-induced bronchoconstriction in aspirin-sensitive asthma, the cellular origin of the LT is not yet clear." | 3.71 | Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. ( Akiyama, K; Endoh, S; Kawagishi, Y; Kobayashi, M; Kudoh, M; Mita, H; Taniguchi, M, 2001) |
| "Aspirin intolerance manifests itself as two clinical symptoms, urticaria/angioedema and asthma." | 3.71 | [The study of 18 cases of aspirin urticaria at dermatology of Yodogawa Christian Hospital--on the difference between aspirin asthma and aspirin urticaria]. ( Hayashi, K; Nakamura, T; Ookami, Y; Tamaki, A, 2001) |
| "House dust mite (HDM) inhalation provocation tests were performed in HDM-sensitive asthmatic inpatients without AIA (HDM group; n = 6), and aspirin oral provocation tests were performed in AIA patients (ASA group; n = 7)." | 3.71 | Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. ( Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, SY, 2002) |
| "The goal of the present study was to identify levels of leukotrienes released by leukocytes and nasal polyps from aspirin-sensitive patients (ASPs) and non-aspirin-sensitive patients (NASPs) after exposure to various concentrations of aspirin." | 3.71 | Aspirin-sensitive versus non-aspirin-sensitive nasal polyp patients: analysis of leukotrienes/Fas and Fas-ligand expression. ( Chow, JM; Na, H; Samter, M; Stankiewicz, JA; Young, MR; Ziroli, NE, 2002) |
| "Aspirin intolerance is characterized by polypous rhinosinusitis, bronchial asthma and adverse reactions to aspirin." | 3.71 | [Zafirlukast in treatment of nasal polyps in patients with aspirin intolerant bronchial asthma--preliminary report]. ( Modrzyński, M; Rapiejko, P; Zawisza, E, 2002) |
| "The A to C transversion in the promoter region of the gene encoding leukotriene C4 synthase (LTC4S) is proposed to be associated with the development of aspirin-induced asthma (AIA)." | 3.71 | Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. ( Akiyama, K; Higashi, N; Kashii, T; Kawagishi, Y; Kobayashi, M; Maruyama, M; Mita, H; Oosaki, R; Taniguchi, M, 2002) |
| "In 5 to 10% of adult patients with asthma, aspirin (acetylsalicylic acid [ASA]) and most other nonsteroidal anti-inflammatory drugs (NSAIDs) precipitate acute asthmatic attacks." | 3.71 | Safety of a cyclooxygenase-2 inhibitor in patients with aspirin-sensitive asthma. ( Alfaya, T; Berges, P; Camacho, E; García-Rodriguez, R; Hinojosa, M; Iscar, A; Martín-García, C, 2002) |
| "Aspirin intolerant asthma (AIA) is a clinically distinct syndrome characterised by the precipitation of asthma attacks following the ingestion of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.71 | The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients. ( Taylor, ML; Thompson, PJ; Vally, H, 2002) |
| " It is generally accepted that in aspirin-induced asthma (AIA) the bronchospasm is provoked by inhibition of prostaglandin synthesis with overproduction of cysteinyl leukotrienes." | 3.71 | [Tolerability of Asacard--controlled-release aspirin and aspirin-induced asthma]. ( Bochenek, G; Gicquel, M; Nizankowska-Mogilnicka, E; Swierczyńska, M; Szczeklik, A; Vivet, P, 2002) |
| "Aspirin causes bronchoconstriction in aspirin-intolerant asthma (AIA) patients by triggering cysteinyl-leukotriene (cys-LT) production, probably by removing PGE2-dependent inhibition." | 3.70 | Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. ( Adamek, L; Austen, FK; Cowburn, AS; Holgate, ST; Lam, BK; Nizankowska, E; Penrose, JF; Sampson, AP; Sladek, K; Soja, J; Szczeklik, A, 1998) |
| "The pathogenic mechanism of aspirin-sensitive asthma (ASA-BA) remains to be further defined." | 3.70 | Role of circulating immune complex in aspirin-sensitive asthma. ( Nahm, DH; Park, HS, 1998) |
| "Nasal provocation tests (NPTs) with lysine-aspirin (L-ASA) have been recently introduced for assessment of aspirin-induced asthma (AIA)." | 3.70 | Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma. ( Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1998) |
| "The immunopathologic mechanism of nasal polyp in aspirin-sensitive asthma remains to be further defined." | 3.70 | Immunohistochemical characterization of cellular infiltrate in nasal polyp from aspirin-sensitive asthmatic patients. ( Nahm, DH; Park, HS; Park, K; Suh, KS; Yim, HE, 1998) |
| "Aspirin-induced asthma (AIA) is frequently accompanied by nasal polyps." | 3.70 | Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient. ( Ogata, Y; Okinaka, Y; Takahashi, M, 1999) |
| "The clinical characteristics of idiopathic nasal polyposis in children (11 males and nine females; median: 12 years; range: 8-15 years) were very similar to those observed in adults (median: 50 years), in particular the relation to asthma (ten of 20 cases) and aspirin intolerance (two Fernand-Widal syndromes of 20 cases)." | 3.70 | [Does idiopathic naso-sinusal polyposis exist in children?]. ( Coffinet, L; Derelle, J; Jankowski, R; Pialoux, R, 1999) |
| "Aspirin intolerance (AI) is characterized by polypous rhinosinusitis, bronchial asthma and adverse reactions to aspirin." | 3.70 | Arachidonic acid metabolism in nasal tissue and peripheral blood cells in aspirin intolerant asthmatics. ( Göde, U; Schäfer, D; Schmid, M; Wigand, ME, 1999) |
| "We studied the urinary excretion of 6-sulphatoxymelatonin, the major metabolite of melatonin, and the effect of different MT doses on ADP-induced platelet aggregation in vitro in 17 ASA patients, 17 patients with aspirin-tolerant asthma (ATA) and 16 healthy subjects." | 3.70 | The role of melatonin in pathogenesis of aspirin-sensitive asthma. ( Evsyukova, HV, 1999) |
| "The aspirin triad (nasal polyposis, asthma and sensitivity to aspirin) is a well-recognized clinical entity, also known as aspirin-induced asthma (AIA)." | 3.70 | Effects of sinus surgery on asthma in aspirin triad patients. ( Higuchi, Y; Kawasaki, M; Nakamura, H; Takahashi, S, 1999) |
| "Asthmatics with aspirin- (ASA) sensitive respiratory disease (ASRD) have a spectrum of respiratory reactions during oral ASA challenge that vary in severity and are temporally associated with leukotriene (LT) formation." | 3.70 | Association of urinary leukotriene E4 excretion during aspirin challenges with severity of respiratory responses. ( Daffern, PJ; Hugli, TE; Muilenburg, D; Stevenson, DD, 1999) |
| "Aspirin-intolerant asthma can be induced not only by acidic analgesics (including acetylsalicylic acid), which effectively inhibit cyclo-oxygenase, but also by cross-reactivity with paraben, and other chemical additives." | 3.70 | Amalgam allergy associated with exacerbation of aspirin-intolerant asthma. ( Amayasu, H; Hasegawa, H; Ishizaki, Y; Mikami, H; Nakagawa, H; Onuma, K; Shoji, T; Yoshida, S, 1999) |
| "Between 8-20 percent of adult asthmatics experience bronchospasm following ingestion of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.70 | NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority. ( Sturtevant, J, 1999) |
| "The mechanism of aspirin (acetylsalicylic acid [ASA]) sensitivity associated with severe asthma and chronic rhinosinusitis with nasal polyps ("aspirin triad") has been attributed to arachidonic metabolism alternations, although the putative biochemical defects have not been elucidated." | 3.70 | Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. ( Iwaszkiewicz, J; Kaliner, MA; Kornatowski, T; Kowalski, ML; Pawliczak, R; Poniatowska, M; Siuda, K; Wozniak, J, 2000) |
| " Polyp score, possible asthma, aspirin sensitivity, and ASA triad were also recorded." | 3.70 | HLA-DRB1, -DQA1, and -DQB1 genotypes in patients with nasal polyposis. ( Endreffy, E; Molnar-Gabor, E; Rozsasi, A, 2000) |
| "The etiology of nasal polyposis is still unknown, although risk factors include Aspirin intolerance, asthma, cystic fibrosis and primary ciliary dyskinesia." | 3.70 | HLA patterns in patients with nasal polyposis. ( Berghold, A; Hofmann, T; Lang-Loidolt, D; Luxenberger, W; Posch, U, 2000) |
| "Approximately 10% of patients with asthma have a distinct clinical entity in which their symptoms are exacerbated by aspirin and most other nonsteroidal anti-inflammatory agents." | 3.70 | 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. ( Baldasaro, M; Drazen, JM; Lam, BK; Penrose, JF; Stevenson, DD; Van Sambeek, R; Yandora, C; Yoshida, S; Zhao, J, 2000) |
| "Cysteinyl leukotrienes (cysLTs) are considered to be the most important mediator involved in the pathogenesis of aspirin-intolerant asthma (AIA)." | 3.70 | Effects of pranlukast, a cysteinyl leukotriene antagonist, on bronchial responsiveness to methacholine in aspirin-intolerant asthmatics treated with corticosteroids. ( Haruta, Y; Hiyama, K; Hozawa, S; Ishioka, S; Maeda, A; Tamagawa, K; Watanabe, T; Yamakido, M, 2000) |
| "Aspirin-intolerant asthma (AIA), a distinct clinical syndrome affecting about 10% of adult asthmatics, appears to be unusually dependent on cysteine leukotriene (cys-LT) overproduction by pulmonary eosinophils." | 3.70 | Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma. ( Bazan-Socha, S; Pierzchalska, M; Sanak, M; Szczeklik, A, 2000) |
| "There is a subset of patients with bronchial asthma who are susceptible to disease exacerbation upon receiving aspirin and other nonsteroidal anti-inflammatory drugs." | 3.70 | Natural history of aspirin-induced asthma. AIANE Investigators. European Network on Aspirin-Induced Asthma. ( Duplaga, M; Nizankowska, E; Szczeklik, A, 2000) |
| "Nasal provocation tests with lysine-aspirin have recently been introduced for assessment of aspirin intolerant asthma." | 3.70 | Intranasal challenge with aspirin in the diagnosis of aspirin intolerant asthma: evaluation of nasal response by acoustic rhinometry. ( Casadevall, J; Mullol, J; Picado, C; Ventura, PJ, 2000) |
| "The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease." | 3.70 | [Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000) |
| "Aspirin-induced asthma (AIA) is a clinical syndrome related to cysteinyl leukotriene overproduction in airways." | 3.70 | A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leucocytes precludes its value for aspirin sensitivity testing in asthma. ( Mastalerz, L; Pierzchalska, M; Sanak, M; Szczeklik, A; Zazula, M, 2000) |
| "The Fernand Widal syndrome combines a nasal polyposis, an asthma and aspirin sensitivity." | 3.70 | [Fernand Widal syndrome: apropos of 2 cases]. ( Ba, O; Cissokho, S; Dia, Y; Diatta, A; Diouf, R; Hane, AA; Kandji, M; Ndiaye, M; Ndiaye, S; Ndir, M; Niang, A, 1999) |
| "Urinary excretion of leukotrienes is greater in patients with aspirin-induced asthma (AIA) than in other patients with asthma in remission, and is greater still during an aspirin-induced attack." | 3.69 | [Serum phospholipase A2 activity in patients with aspirin-induced asthma]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1995) |
| "The purpose of this study was to investigate the risk of transitional cell carcinoma among subjects with an intake of acetaminophen, aspirin, some other drugs and with some intercurrent diseases." | 3.69 | Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study. ( Gerhardsson de Verdier, M; Steineck, G; Wiholm, BE, 1995) |
| "An abnormal platelet release of oxygen-free radicals has been described in acetylsalicylic acid (aspirin)-induced asthma, a finding which might suggest the existence of an intrinsic, specific platelet abnormality of arachidonic acid metabolism in these patients." | 3.69 | In vitro release of arachidonic acid metabolites, glutathione peroxidase, and oxygen-free radicals from platelets of asthmatic patients with and without aspirin intolerance. ( Ballester, E; Gelpí, E; Mullol, J; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J; Vives-Corrons, JL, 1995) |
| "We surveyed 850 patients with bronchial asthma and investigated such clinical features as the frequency of aspirin-induced asthma and hypersensitivity to steroids in the 457 available answers." | 3.69 | [Examination on aspirin-induced asthma and hypersensitivity to steroids--a questionnaire to 850 asthma on hypersensitivity to non-steroidal anti-inflammatory drugs and hypersensitivity to steroids]. ( Adachi, M; Enomoto, T; Horikoshi, S; Ichihashi, K; Imai, T; Matsuura, T; Mita, S; Miura, Y; Okada, T, 1995) |
| " Compared with monocytes from normal volunteers (n = 5), monocytes from patients with aspirin-sensitive asthma (n = 10) released increased amounts of thromboxane B2 (1060 +/- 245 pg/ml vs 456 +/- 62 pg/ml), leukotriene B4 (861 +/- 139 pg/ml vs 341 +/- 44 pg/ml), and leukotriene C4 (147 +/- 31 pg/ml vs 56 +/- 6 pg/ml) at baseline." | 3.69 | Inhibition of monocyte leukotriene B4 production after aspirin desensitization. ( Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL, 1995) |
| "A very small number of patients with asthma show symptomatic improvement after administration of aspirin and other cyclooxygenase inhibitors." | 3.69 | Lipoxygenase inhibitor-provoked acute asthma in a patient with asthma relieved by aspirin. ( Chida, K; Hayakawa, H; Imokawa, S; Sato, A; Taniguchi, M; Toyoshima, M, 1995) |
| "This paper reports that substitution of Glucosidorum Tripterygii Totorum (GTT) for cortical hormone used to treat corticosteroid-dependent type of aspirin asthma, 60 mg, 3 times a day." | 3.69 | [Treatment of 36 corticosteroid-dependent type of aspirin asthma patients with Glucosidorum Tripterygii totorum]. ( Gao, JT, 1994) |
| "Inhalation of aerosolized lysine-aspirin (L-ASA) has been described as an alternative diagnostic method in aspirin-sensitive asthma." | 3.69 | Early and late onset asthmatic responses following lysine-aspirin inhalation in aspirin-sensitive asthmatic patients. ( Park, HS, 1995) |
| "Patients with aspirin sensitive asthma (ASA) can be desensitized to aspirin but the mechanisms by which this happens are unknown." | 3.69 | The effect of aspirin desensitization on urinary leukotriene E4 concentrations in aspirin-sensitive asthma. ( Bell, GS; Lee, TH; Nasser, SM; Patel, M, 1995) |
| "The analysis of case history, clinical, laboratory and instrumental findings, objectively characterizing the patient's condition in two alternative groups (nonaspirin and aspirin bronchial asthma) enabled the authors to create a functional diagnostic model for aspirin bronchial asthma." | 3.69 | [The diagnosis of aspirin-induced asthma by using a functional model]. ( Evsiukova, EV; Poddubskiĭ, GA; Razorenov, GI, 1995) |
| "Two female patients have been described in whom peripheral vasculitis with cold sensitivity preceded by about 5 years typical symptoms of aspirin-induced asthma." | 3.69 | Autoimmune vasculitis preceding aspirin-induced asthma. ( Bartosik, A; Dyczek, A; Milewski, M; Musiał, J; Szczeklik, A, 1995) |
| "Biochemical and immunological studies were performed to study hepatic function in 137 patients, out of whom 74 were found to have aspirin-induced bronchial asthma, 23 atopic bronchial asthma, 23 infectious allergic bronchial asthma, 17 chronic persistent hepatitis." | 3.69 | [Liver function in patients with aspirin-induced bronchial asthma]. ( Efimova, NIu; Sizykh, TP, 1994) |
| " 4) The basal levels of urinary LTE4 of seven aspirin-sensitive asthmatics were elevated as compared with five asthmatics without aspirin sensitivity (358." | 3.69 | [Fundamental studies on the measurement of urinary leukotriene E4]. ( Hayakawa, T; Kawasaki, A; Kobayashi, M; Maeda, Y; Mita, H; Mizushima, Y; Oosaki, R; Shida, T; Yamada, T, 1994) |
| "The inflammatory cell infiltrate in bronchial biopsies of 12 aspirin-sensitive asthmatic (ASA) subjects and eight non-aspirin-sensitive (non-ASA) control subjects have been compared." | 3.69 | Inflammatory cell populations in bronchial biopsies from aspirin-sensitive asthmatic subjects. ( Barker, J; Christie, PE; Lee, TH; Nasser, SM; Pfister, R; Schmitz-Schumann, M; Sousa, AR, 1996) |
| "It is believed that aspirin (ASA) and other nonsteroidal antiinflammatory drugs elicit dysponea in ASA sensitive asthmatics by blocking the cyclooxygenase." | 3.69 | [The influence of misoprostol on post-aspirin bronchoconstriction in patients with aspirin sensitive asthma]. ( Szmidt, M; Wasiak, W, 1995) |
| "The aspirin-induced bronchoconstriction in patients with aspirin-sensitive asthma is caused by cysteinyl leukotriene release." | 3.69 | Effect of endobronchial aspirin challenge on inflammatory cells in bronchial biopsy samples from aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Nasser, S; Pfister, R; Schmitz-Schumann, M; Sousa, AR; Walls, A, 1996) |
| "Aspirin-induced asthma (AIA) should be recognized as an important types of bronchial asthma for the following reasons." | 3.69 | [Aspirin-induced asthma as an important type of bronchial asthma]. ( Sakakibara, H; Suetsugu, S, 1995) |
| "Lowered selenium (Se) status has been observed in asthma patients." | 3.69 | Selenium status is decreased in patients with intrinsic asthma. ( Gazdík, F; Ginter, E; Kadrabová, J; Kovaciková, Z; Mad'aric, A; Podivínsky, F, 1996) |
| " In contrast, the sinusitis of the aspirin triad syndrome is often fulminate, expansive, and recurrent, and complications may be more frequent." | 3.69 | Orbital complications of sinusitis in the aspirin triad syndrome. ( Massaro, BM; McFadden, EA; Toohill, RJ; Woodson, BT, 1996) |
| " CD62P and CD63) which mediate interactions between platelets and other cells may be important in the pathogenesis of aspirin-sensitive asthma." | 3.69 | Differential expression of platelet activation markers in aspirin-sensitive asthmatics and normal subjects. ( Misso, NL; Stewart, GA; Taylor, ML; Thompson, PJ, 1996) |
| "Appreciable numbers of aspirin-sensitive asthmatic patients have chronic steroid-dependent severe asthmatic symptoms." | 3.69 | Complete resolution of airway hyperresponsiveness in aspirin-sensitive asthmatic patients. ( Park, HS, 1996) |
| "In vitro cysteinyl leukotriene (cLT) release from blood leukocytes was measured in eight normal individuals (NI), nine patients with nasal polyps (NP) without aspirin intolerance, and eight patients with NP, asthma, and aspirin intolerance (AI)." | 3.69 | Increased in vitro cysteinyl leukotriene release from blood leukocytes in patients with asthma, nasal polyps, and aspirin intolerance. ( Klimek, L; Mewes, T; Riechelmann, H, 1996) |
| "We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain." | 3.69 | Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996) |
| "Aspirin-sensitive patients with asthma experience continuous inflammation of their nasal and sinus tissues, complicated by recurrent sinusitis, which frequently leads to asthma attacks." | 3.69 | Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. ( Christiansen, SC; Hankammer, MA; Mathison, DA; Simon, RA; Stevenson, DD, 1996) |
| " Upon preoperative medical evaluation, it was discovered that she was "allergic" to aspirin and suffered from stress-induced asthma." | 3.69 | Ketorolac-induced bronchospasm in an aspirin-intolerant patient. ( Bennett, CR; Chen, AH, 1994) |
| "We have shown that inhalation of lysine aspirin enhances leukotriene production in the lungs of patients with aspirin-induced asthma (AIA)." | 3.69 | Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics. ( Dworski, R; Nizankowska, E; Oates, J; Sheller, J; Sladek, K; Soja, J; Szczeklik, A, 1996) |
| "Asthmatic triad (AT) is a clinical syndrome incorporating bronchial asthma (BA), recurrent nasal and sinus polyps, intolerance of aspirin, derivatives of pirasolone and other nonsteroid antiinflammatory drugs." | 3.69 | [The in-vivo test of the inhibition of leukocyte natural migration with aspirin and analgin in the specific diagnosis of the asthmatic triad]. ( Kanchurina, NA; Poroshina, IuA; Prasolova, NI; Zemskov, VM, 1996) |
| "Aspirin-induced asthma (AIA) affects one in 10 individuals with adult-onset asthma." | 3.69 | Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes. ( Bochenek, G; Cookson, WO; Dekker, JW; Dyczek, A; Nizankowska, E; Pile, K; Schmitz-Schumann, M; Szczeklik, A, 1997) |
| "The objective of this study was to define the participation of cysteinyl leukotrienes (LTs) or thromboxane A2 in the pathogenesis of aspirin-sensitive asthma (ASA)." | 3.69 | Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. ( Akiyama, K; Kobayashi, M; Mita, H; Mizushima, Y; Oosaki, R; Shida, T, 1997) |
| "Increased numbers of eosinophils and mast cells in the bronchial mucosa are characteristic features in subjects with aspirin-sensitive asthma." | 3.69 | Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in aspirin-sensitive and non-aspirin-sensitive asthmatic airways. ( Christie, PE; Lams, BE; Lee, TH; Pfister, R; Schmitz, M; Sousa, AR, 1997) |
| "The expression of COX-1 and COX-2 isoenzymes has been studied in the bronchial mucosa of 10 normal and 18 asthmatic subjects, 11 of whom had aspirin-sensitive asthma (ASA) and seven had non-aspirin-sensitive asthma (NASA) RESULTS: There was a significant fourfold and 14-fold increase, respectively, in the epithelial and submucosal cellular expression of COX-2, but not of COX-1, in asthmatic patients." | 3.69 | Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma. ( Christie, PE; Lane, SJ; Lee, TH; Nasser, SM; Pfister, R; Schmitz-Schumann, M; Sousa, Ar, 1997) |
| "Platelet aggregation, pulmonary microcirculation and external respiration were studied against clinical appearance of the disease in 20 patients with aspirin-sensitive asthma (ASA) and 10 asthmatics without aspirin intolerance." | 3.68 | [The effect of disorders of thrombocyte functional activity on the microcirculatory status in the lungs and on external respiratory function in patients with aspirin-induced asthma]. ( Amoashiĭ, GS; Amosov, VI; Evsiukova, EV; Fedoseev, GV; Petrishchev, NN; Sinitsyna, TM, 1993) |
| "A long-term follow-up (within 18 months) has been conducted of bronchial asthma (BA) patients (a total of 29 cases with atopic, aspirin and mixed BA forms) subjected to thrombocytapheresis." | 3.68 | [The late results of thrombocytapheresis in bronchial asthma patients]. ( Alieva, KM; Bobkov, EV; Emirova, AS; Karnaushkina, MA; Tatarskiĭ, AR, 1993) |
| "We wanted to determine whether the airway response to inhaled leukotriene C4 (LTC4) is similar to inhaled leukotriene E4 (LTE4) in aspirin-sensitive asthma and, therefore, determined airway responsiveness to histamine, LTC4 and LTE4 in seven aspirin-sensitive subjects and 13 control asthmatic subjects, who were tolerant of aspirin." | 3.68 | Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects. ( Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW, 1993) |
| " Studies concerning the sensitivity, specificity and tolerance of the new intranasal provocation procedure using lysine-ASA were based primarily on cases of bronchial asthma and yielded differing results." | 3.68 | [Intranasal provocation with lysine acetylsalicylic acid]. ( Brasch, J; Cornelius, M; Mertens, J; Wellbrock, M, 1993) |
| "It is well known that nasal polyps frequently develop in patients with aspirin-induced asthma, which is thought to be a non-atopic disease." | 3.68 | [Immunohistological study of eosinophilic infiltration of nasal polyps in aspirin-induced asthma]. ( Kumagami, H; Takamura, H; Takasaki, K; Tsurumoto, H; Yoshimi, R, 1993) |
| "Inhalation challenge with lysine acetylsalicylate (L-ASA) is often used to diagnose aspirin-induced asthma." | 3.68 | Dosimeter inhalation test with lysine acetylsalicylate for the detection of aspirin-induced asthma. ( Cocco, G; Masi, C; Melillo, G; Padovano, A, 1993) |
| "To further assess this association, we studied two populations of aspirin-sensitive subjects and aspirin-tolerant subjects with asthma." | 3.68 | An analysis with sequence-specific oligonucleotide probes of the association between aspirin-induced asthma and antigens of the HLA system. ( Christie, PE; Kemeny, DM; Lee, TH; Lympany, PA; Schmitz-Schumann, M; Welsh, KI, 1993) |
| "Methacholine provocation test, bronchial reversibility test, aspirin inhalation test, and cough provocation test have been performed at our institute to examine pathophysiology and to diagnose bronchial diseases." | 3.68 | [Bronchial provocation test in bronchial asthma]. ( Fujimura, M; Hashimoto, T; Kamio, Y, 1993) |
| "In order to examine the hypothesis that in aspirin-induced asthma (AIA) cyclooxygenase inhibition is associated with enhanced release of leukotrienes (LTs), we measured urinary leukotriene E4 (LTE4) and 11-dehydro-thromboxane B2 (TXB2) (as a measure of cyclooxygenase production) following challenge with oral aspirin or inhaled methacholine, in 10 AIA patients." | 3.68 | Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthma. ( Sladek, K; Szczeklik, A, 1993) |
| "We attempted to determine the relationship of nasal polyps to histamine (HA) metabolism." | 3.68 | Histamine metabolism in nasal polyps. ( Abe, Y; Fukui, H; Harada, T; Imamura, I; Irifune, M; Matsunaga, T; Ogino, S, 1993) |
| "Three groups, comprising normal subjects (n = 10), aspirin-sensitive asthmatics (ASA+; n = 10) and aspirin-insensitive asthmatics (ASA-; n = 10) were entered into a blinded, parallel group study to asses the modulating effect of aspirin (ASA; 0." | 3.68 | The effect of aspirin on mononuclear cells in aspirin-sensitive asthmatics and control subjects. ( Stewart, GA; Taylor, ML; Thompson, PJ, 1993) |
| " The in vitro effect of aspirin on platelet aggregation and ATP release induced by platelet activating factor (PAF), arachidonic acid (AA) and collagen (COL) was assessed in 10 aspirin-sensitive (ASP+) asthmatic patients and 10 normal subjects." | 3.68 | The differential effect of aspirin on human platelet activation in aspirin-sensitive asthmatics and normal subjects. ( Stewart, GA; Taylor, ML; Thompson, PJ, 1993) |
| "The etiology of aspirin-sensitive asthma is unknown, but a plausible hypothesis is that the inhibitory effect of aspirin on the cyclooxygenase enzyme increases formation of bronchoconstrictor leukotrienes via "shunting" of unmetabolized arachidonic acid into metabolism by the 5-lipoxygenase enzyme." | 3.68 | Increased excretion of leukotriene E4 during aspirin-induced asthma. ( Fitzgerald, GA; Knapp, HR; Sladek, K, 1992) |
| " We assayed urinary LTE4 in 17 normal subjects, 31 subjects with asthma without aspirin sensitivity, and 10 aspirin-sensitive subjects." | 3.68 | Urinary leukotriene E4 in bronchial asthma. ( Christie, PE; Hawksworth, RJ; Lee, TH; Smith, CM; Thien, FC, 1992) |
| " During aspirin-induced bronchospasm, release of leukotriene B4 increased significantly (45." | 3.68 | Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. ( Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL, 1992) |
| "A 40-year-old woman who had been diagnosed as having aspirin-induced asthma was admitted with stridor." | 3.68 | [A case of aspirin-induced asthma due to ketoprofen adhesive agent]. ( Goto, K; Nakahara, K; Sakai, S; Tanaka, H, 1992) |
| "Thirteen asthmatic subjects (six aspirin tolerant and seven aspirin intolerant) in a stable clinical condition and ten healthy subjects were studied." | 3.68 | Platelet kinetics in asthmatic patients with and without aspirin intolerance. ( Alonso, A; Casals, F; Picado, C; Plaza, V, 1992) |
| "Up to 10% of all asthmatics are intolerant to aspirin reacting with bronchospasm after intake of this drug." | 3.68 | [Current aspects of analgetics-induced asthma]. ( Rothe, T, 1992) |
| " Thirty patients suffered from polyps and bronchial hyperreactivity; 12 patients in this group also suffered from aspirin intolerance." | 3.68 | Incidence of medico-surgical treatment for nasal polyps on the development of associated asthma. ( Goetz, R; Jankowski, R; Moneret-Vautrin, DA; Wayoff, M, 1992) |
| "We report a case of asthma that was relieved by aspirin and other cyclooxygenase inhibitors." | 3.68 | [A case of asthma relieved by aspirin--the first case in Japan and investigation of its mechanism]. ( Chida, K; Hayakawa, H; Imokawa, S; Nakazawa, K; Sato, A; Taniguchi, M; Toyoshima, M, 1992) |
| "We have determined IgG subclass concentrations in 100 patients with aspirin-induced asthma and 80 healthy controls." | 3.68 | Altered distribution of IgG subclasses in aspirin-induced asthma: high IgG4, low IgG1. ( Milewski, M; Nizankowska, E; Roehlig, F; Schmitz-Schumann, M; Szczeklik, A; Virchow, C, 1992) |
| "Aspirine-sensitive asthma (ASA) is a disease defined only by clinical criteria." | 3.68 | In vitro study of platelets and circulating mononuclear cells of subjects presenting an intolerance to aspirin. ( Bezian, JH; Cabanieu, G; Gualde, N; Guez, S, 1992) |
| "Histamine release induced by platelet-activating factor (PAF) from leukocytes of aspirin-sensitive subjects with asthma was higher than that from normal control subjects, despite the similarity of anti-IgE-induced histamine release." | 3.68 | Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma. ( Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A, 1990) |
| " ASA challenges were performed in 17 ASA-sensitive patients with asthma and rhinosinusitis, and tryptase and histamine levels were measured in their venous blood samples." | 3.68 | Tryptase and histamine release during aspirin-induced respiratory reactions. ( Bosso, JV; Schwartz, LB; Stevenson, DD, 1991) |
| " We experienced a case of an aspirin-sensitive asthmatic patient who developed a broncho-obstructive reaction after taking 100 mg of sodium salicylate." | 3.68 | Sodium salicylate sensitivity in an asthmatic patient with aspirin sensitivity. ( Cho, DI; Kim, JW; Lim, YS; Park, HS; Rhu, NS; Suh, JE, 1991) |
| "The following bronchial provocation tests were carried out: 310 with acetylcholine, 216 with submaximal physical exercise, 246 with cold air inhalation, and 103 with aspirin in healthy subjects, relatives of bronchial asthma patients, in patients with preasthma and asthma in a stage of exacerbation abatement or remission." | 3.68 | [The results of the dynamic observation of bronchial hyperreactivity in risk-group subjects and in bronchial asthma patients. Some corrective procedures]. ( Didur, MD; Emel'ianov, AV; Evsiukova, EV; Nazarova, VA; Shchemelinina, TI; Sinitsina, TM, 1991) |
| "Upon comparison of functional activity of platelets and their response to aspirin in 20 subjects with aspirin bronchial asthma, 19 patients with non-aspirin bronchial asthma and 21 healthy controls it was found out that in aspirin asthma platelet count is elevated, their response to aggregation inductors enhances while to aspirin is abnormal, plasmic thromboxane level is reduced." | 3.68 | [Characteristics of functional activity of thrombocytes in patients with "aspirin" bronchial asthma]. ( Evsiukova, EV, 1991) |
| " In aspirin asthma following aspirin bronchial provocation NCA increases in 50% to 100% of the studied patients." | 3.68 | [Neutrophil chemotactic activity after administration of aspirin during aspirin tolerance in patients with asthma and aspirin hypersensitivity]. ( Grzegorczyk, J; Grzelewska-Rzymowska, I; Rozniecki, J; Szmidt, M, 1991) |
| "Alpha-1 antitrypsin (A-1-AT) levels were determined in 46 patients with aspirin sensitive asthma using the Eriksson method." | 3.68 | [Alpha 1-antitrypsin and its phenotype in patients with asthma and aspirin hypersensitivity]. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1991) |
| "In order to determine if aspirin sensitivity effects leukocyte reaction in aspirin sensitive asthma patients the authors studied the influence of aspirin on chemiluminescence in 12 aspirin sensitive asthmatics and 13 non-aspirin asthmatics." | 3.68 | [Effect of aspirin on FMLP (formyl-meth-leu-phe)-stimulated leukocytes in patients with asthma and hypersensitivity to aspirin]. ( Garliński, P; Grzelewska-Rzymowska, I; Rozniecki, J; Szmidt, M, 1991) |
| "Inhalation and nasal aspirin challenge has been investigated in asthma patients with co-existing rhinitis." | 3.68 | Inhalation and nasal challenge in the diagnosis of aspirin-induced asthma. ( Davies, BH; Pawlowicz, A; Williams, WR, 1991) |
| "A study is presented of 66 patients with aspirin bronchial asthma (BA) and the clinical, pathogenetical, immunological and allergological state of these patients is described." | 3.68 | [The clinico-immunological and allergological characteristics of aspirin-induced asthma]. ( Kozachuk, IA; Markov, AE, 1991) |
| "Selenium status and its relationship to lowered platelet glutathione peroxidase activity was investigated in 18 subjects with aspirin (ASA)-induced asthma and in asthmatic and non-asthmatic ASA-tolerant subjects." | 3.68 | Selenium status in relation to reduced glutathione peroxidase activity in aspirin-sensitive asthma. ( Day, JP; Miller, PF; Pearson, DJ; Suarez-Mendez, VJ, 1991) |
| "Although the pathogenesis of aspirin-sensitive asthma remains to be specified, it is known that in the presence of acetylsalicylic acid or non-steroidal anti-inflammatory drugs, platelets from aspirin-sensitive asthmatics have been described as generating cytocidal mediators that killed parasite targets such as Schistosoma mansoni larvae." | 3.68 | Plasmapheresis in a patient with severe asthma associated with auto-antibodies to platelets. ( Capron, A; Dracon, M; Joseph, M; Lassalle, P; Ramon, P; Tonnel, AB, 1990) |
| "In patients with aspirin-sensitive asthma, no significant changes in plasma beta-thromboglobulin or bicyclic prostaglandin (PG) E2 were observed during aspirin challenge." | 3.68 | In vitro tests for the diagnosis of aspirin-sensitive asthma. ( Davies, BH; Pawlowicz, A; Williams, WR, 1990) |
| " Blood platelets from patients with aspirin-sensitive asthma (ASA) generated cytotoxic mediators in the presence of aspirin." | 3.68 | The abnormal in vitro response to aspirin of platelets from aspirin-sensitive asthmatics is inhibited after inhalation of nedocromil sodium but not of sodium cromoglycate. ( Capron, A; Joseph, M; Lassalle, P; Marquette, CH; Tonnel, AB; Tsicopoulos, A; Vorng, H, 1990) |
| " A 31-year-old female with intrinsic bronchial asthma and aspirin sensitivity was admitted to our hospital because of an episode of asthmatic attack." | 3.68 | [Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient]. ( Hirano, T; Kitada, O; Nakamura, H; Shiratusuki, N; Suenaga, N; Sugita, M; Uyama, O, 1990) |
| "An aspirin test has been performed in 100 asthma patients." | 3.68 | [Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma]. ( Didkovskiĭ, NA; Evseev, NG; Treskunov, VK; Zakharzhevskaia, TV, 1990) |
| "An 11-year retrospective study was conducted to evaluate the surgical treatment of sinusitis in aspirin-triad patients." | 3.68 | Surgery for sinusitis and aspirin triad. ( Fink, JN; Kany, RJ; McFadden, EA; Toohill, RJ, 1990) |
| "One hundred seven known aspirin (ASA)-sensitive patients with rhinosinusitis-asthma were studied from 1975 to 1988." | 3.68 | Long-term effects of aspirin desensitization--treatment for aspirin-sensitive rhinosinusitis-asthma. ( Mathison, DA; Simon, RA; Stevenson, DD; Sweet, JM, 1990) |
| " In 1986, we advised that asthma from sulphite intolerance was more frequent in patients who presented with illness from aspirin or the Fernand Widal syndrome." | 3.68 | [Fernand Widal syndrome and sulfite intolerance. Therapeutic problems in general and ORL problems in particular]. ( Bonneau, JC; Drouet, M; Fourrier, E; Le Sellin, J; Sabbah, A, 1990) |
| "Differences in the character of platelet response to aggregation inducers and inhibitors was revealed in atopy and pseudoallergy, with aspirin-sensitive asthma being chosen as its model." | 3.68 | [Changes in the functional and biochemical characteristics of the thrombocytes in the side effects of nonsteroidal anti-inflammatory preparations]. ( Astaf'eva, NG, 1990) |
| "Eighteen patients with a history of urticaria or asthma, or both, induced by aspirin were studied before and after provocation of symptoms with aspirin." | 3.67 | Effect of aspirin in "aspirin sensitive" patients. ( Asad, SI; Frankland, AW; Kemeny, DM; Lessof, MH; Youlten, LJ, 1984) |
| "In order to determine if mast cell mediators are released during aspirin challenge in aspirin-sensitive asthmatics, we measured neutrophil chemotactic activity, which has been shown to be an indicator of mast cell degranulation." | 3.67 | Identification and characterization of neutrophil chemotactic activity in aspirin-induced asthma. ( Binder, R; Braman, SS; Center, DM; Downing, ET; Glassroth, J; Hollingsworth, HM, 1984) |
| "Neutrophil chemotactic activity (NCA) following oral challenge with aspirin (ASA) was determined in ASA-intolerant asthmatic subjects, and in ASA-tolerant asthmatic and normal subjects." | 3.67 | Neutrophil chemotactic factor of anaphylaxis (NCF-A) release in aspirin-induced asthma. ( Capsoni, F; Ortolani, C; Pastorello, E; Restuccia, M; Riboldi, PS; Zanussi, C; Zocchi, M, 1984) |
| " There was no significant difference between the polyp histamine levels in patients with a history of asthma, aspirin hypersensitivity, hay fever and positive skin tests." | 3.67 | Free histamine in nasal polyp fluid. ( Bickerton, R; Drake-Lee, AB; McLaughlan, P, 1984) |
| "The effects of regular aspirin ingestion after aspirin-desensitization were evaluated in 10 aspirin-intolerant asthmatic patients." | 3.67 | Effects of chronic aspirin ingestion in aspirin-intolerant asthmatic patients. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| "Three asthmatic patients with a history of bronchoconstriction after aspirin ingestion were challenged with a new analgesic, zomepirac sodium (Zomax), for determination of sensitivity to this drug." | 3.67 | Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics. ( Lumry, WR; Pleskow, WW; Simon, RA, 1984) |
| "Oral provocation tests using aspirin (n = 55), tartrazine (n = 37) and benzoate (n = 28) were performed in 55 asthmatic patients." | 3.67 | [Indications for the aspirin provocation test in the asthmatic]. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| " No correlations were found between premenstrual exacerbation of asthma and symptoms of premenstrual tension, consumption of aspirin, use of the contraceptive pill, cycle length, or behaviour of asthma during pregnancy." | 3.67 | Premenstrual exacerbation of asthma. ( Coutts, II; Finnegan, OC; Gibbs, CJ; Lock, R; White, RJ, 1984) |
| "Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA)." | 3.67 | Aspirin tolerance induced in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1984) |
| "The role of a commonly ingested food additive, the preservative sodium metabisulfite (MBS), and aspirin (ASA), in chronic asthma has been studied in 29 children." | 3.67 | Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma. ( Mellis, CM; Towns, SJ, 1984) |
| "An aspirin- and tartrazine-sensitive asthmatic patient underwent a desensitization to the adverse effects of aspirin by oral aspirin challenges." | 3.67 | Decreased sensitivity to tartrazine after aspirin desensitization in an asthmatic patient intolerant to both aspirin and tartrazine. ( Bracamonte, M; Duchateau, J; Michel, O; Naeije, N; Sergysels, R, 1984) |
| "The levels of leukotriene C4 (LTC4), leukotriene B4 (LTB4), prostaglandin E2 (PGE2), and histamine were measured in nasal lavage fluids obtained from aspirin-sensitive, desensitized aspirin-sensitive, and aspirin-insensitive asthmatics and normal volunteers before and after ingestion of aspirin." | 3.67 | Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin. ( Ferreri, NR; Howland, WC; Spiegelberg, HL; Stevenson, DD, 1988) |
| "A sulpyrin inhalation test was given to 13 patients with aspirin-induced asthma (AIA) and 8 patients with non-aspirin-induced asthma (non-AIA) to observe the changes in plasma histamine levels before and after challenges." | 3.67 | [The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients]. ( Adachi, M; Kokubu, F; Maeda, M; Okada, Y; Takahashi, T; Tanabe, Y; Tsuji, A, 1989) |
| "It is well known that nasal polyps occur at high frequency in aspirin-sensitive asthma (ASA)." | 3.67 | Etiology of nasal polyps associated with aspirin-sensitive asthma. ( Kumazawa, T; Maeda, N; Tomoda, K; Tsuji, H; Yamashita, T, 1989) |
| "Airway responsiveness to histamine and leukotriene E4 (LTE4) has been compared between five subjects with aspirin-induced asthma (AIA) and 15 asthmatic subjects without aspirin sensitivity (non-AIA)." | 3.67 | Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. ( Arm, JP; Lee, TH; O'Hickey, SP; Spur, BW, 1989) |
| " Furthermore, nedocromil sodium inhibited the abnormal response to aspirin of platelets from aspirin-sensitive asthmatics at therapeutic concentrations." | 3.67 | Nedocromil sodium inhibition of IgE-mediated activation of human mononuclear phagocytes and platelets from asthmatics. ( Capron, A; Joseph, M; Thorel, T; Tonnel, AB; Tsicopoulos, A, 1989) |
| "The paper treats long-term results of aspirin treatment of patients with aspirin-induced bronchial asthma." | 3.67 | [The late results of aspirin treatment in patients with aspirin-induced bronchial asthma]. ( Chuchalin, AG; Priputenova, ZV; Sulakvelidze, IV, 1989) |
| "Oral aspirin test was performed in 50 asthma patients." | 3.67 | [Hemosorption in the treatment of aspirin-induced bronchial asthma]. ( Didkovskiĭ, NA; Evseev, NG; Shmeleva, TK; Treskunov, VK; Zakharzhevskaia, TV, 1989) |
| "We evaluated the effects of corticosteroid pretreatment on the intensity of adverse reactions to aspirin during carefully controlled aspirin challenges in 13 aspirin-sensitive asthmatics." | 3.67 | Glucocorticosteroids attenuate aspirin-precipitated adverse reactions in aspirin-intolerant patients with asthma. ( Nizankowska, E; Szczeklik, A, 1989) |
| "Aspirin (ASA)-induced asthma is a distinct clinical syndrome in which bronchoconstrictive response to nonsteroidal anti-inflammatory drugs can be predicted on the basis of their in vitro activity as inhibitors of cyclooxygenase." | 3.67 | An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma. ( Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Nizankowska, E; Radomski, M; Szczeklik, A; Wandzilak, M, 1988) |
| " Thirty-four patients (17 with asthma and 17 with urticaria), whose case history suggested such intolerance, were challenged orally with increasing doses of seven compounds: acetylsalicylic acid, glafenine, sodium benzoate, sulfur dioxide, potassium sorbate, sodium glutamate, and tartrazine." | 3.67 | Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria. ( Frei, PC; Genton, C; Pécoud, A, 1985) |
| "Two cases of aspirin-intolerant asthma whose polymorphonuclear leukocytes demonstrated hypersensitivity to sulpyrin in vitro were reported." | 3.67 | Two cases of aspirin-intolerant asthma whose leukocytes demonstrated hypersensitivity to sulpyrin. ( Kuroume, T; Mochizuki, H; Morikawa, A; Tajima, K; Tokuyama, K, 1989) |
| "Since inhibition of cyclo-oxygenase precipitates asthmatic attacks in patients with aspirin idiosyncrasy, we have evaluated the effects of pharmacological inhibition of the next enzyme in arachidonic acid cascade, i." | 3.67 | Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma. ( Dworski, R; Gajewski, P; Nizankowska, E; Szczeklik, A, 1987) |
| " They concern: (1) the existence of a specific receptor for IgE on the platelet surface; (2) its close association with a platelet membrane glycoprotein of essential functional importance, the GPIIb-IIIa complex; (3) the observation, in extrinsic allergic asthma, of an allergen-specific IgE-dependent platelet activation; (4) the identification, in aspirin-sensitive asthma, of a similar, but non-IgE-dependent, platelet activation selectively induced by cyclo-oxygenase inhibitors, and prevented by salicylate." | 3.67 | New functions for platelets and their pathological implications. ( Ameisen, JC; Auriault, C; Caen, J; Capron, A; Joseph, M; Tonnel, AB, 1985) |
| " We have investigated GSH-Px activity in 12 patients with intrinsic asthma and food and aspirin intolerance." | 3.67 | Lowered glutathione-peroxidase activity in asthmatic patients with food and aspirin intolerance. ( de Wahl, K; Malmgren, R; Theorell, H; Unge, G; Zetterström, O, 1986) |
| "A hypothesis is presented which states that aspirin-induced asthma results from chronic viral infection." | 3.67 | Aspirin-induced asthma as a viral disease. ( Szczeklik, A, 1988) |
| "Platelets isolated from patients with aspirin-induced asthma (ASA patients) react abnormally in vitro to aspirin and to non-steroid anti-inflammatory drugs (NSAID), by generating cytocidal molecules, that can kill parasitic larvae and to oxygen-dependent free radicles, which may be detected by chemiluminescence, although these drugs do not have a similar effect on platelets from normal donors or allergic asthmatics." | 3.67 | [Blood platelets and asthma caused by aspirin]. ( Ameisen, JC; Capron, A; Joseph, M; Martinot, JB; Tonnel, AB, 1987) |
| " Before immunotherapy, all patients had a complete evaluation of the severity of asthma by symptom-medication scores and a pulmonary function test, as well as a study of other triggering factors by checking on seasonal and perennial allergens, sinusitis, and other possible causes, such as aspirin intolerance; 196 patients were investigated between 9 and 12 months after the onset of the survey by means of pulmonary function tests and symptom-medication scores." | 3.67 | Specific immunotherapy with a standardized Dermatophagoides pteronyssinus extract. II. Prediction of efficacy of immunotherapy. ( Bousquet, J; Clauzel, AM; Dhivert, H; Guérin, B; Hejjaoui, A; Michel, FB; Skassa-Brociek, W, 1988) |
| "The effect of a fish oil enriched diet containing about 3 g of eicosapentaenoic acid was studied in 10 patients with aspirin intolerant asthma." | 3.67 | Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study. ( Agusti-Vidal, A; Castillo, JA; Coronas, A; Ordinas, A; Picado, C; Pujades, M; Schinca, N, 1988) |
| "Plasma aspirin esterase activity and cholinesterase activity were reduced in patients with aspirin sensitive asthma and aspirin sensitive urticaria compared to asthmatic and dermatological controls." | 3.67 | Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria. ( Asad, SI; Lessof, MH; Rawlins, MD; Williams, FM, 1987) |
| "38% of subjects who presented with aspirin (Acetyl-salicylic acid AAS)-included asthma were also found to be intolerant to metabisulphites (MBS)." | 3.67 | [Intolerance to metabisulfites in asthma induced by aspirin]. ( Bonneau, JC; Drouet, M; Ernoult, C; Le Sellin, J; Sabbah, A, 1987) |
| "We have observed in some patients that some Aspirin sensitive asthmatic present also a dyspnea after wine or foods containing sulfites ingestion." | 3.67 | [Reactions to metabisulfites in aspirin-induced asthma]. ( Bonneau, JC; Drouet, M; Le Sellin, J; Sabbah, A, 1987) |
| "Asthma, aspirin intolerance and nasal polyps form a triad of aspirin-induced asthma (AIA)." | 3.67 | Aspirin-induced asthma and nasal polyps. ( Harada, T; Irifune, M; Matsunaga, T; Nagano, T; Ogino, S; Okawachi, I, 1986) |
| "Many peripherally acting analgesic and anti-inflammatory drugs, including pyrazolone derivatives, can precipitate idiosyncratic hypersensitivity reactions in intrinsic asthmatics." | 3.67 | Pyrazolones and analgesic asthma syndrome. ( Juhl-Schaub, E; Schmitz-Schumann, M; Virchow, C, 1986) |
| "Nearly 700 specimens of polyps and sinus tissues from 12 patients with asthma and aspirin idiosyncrasy were studied with histochemical and immunofluorescent immunoglobulin techniques." | 3.67 | Histopathology and immunofluorescent immunoglobulins in asthmatics with aspirin idiosyncrasy. ( Carr, R; English, GM; Farr, R; Spector, S, 1987) |
| "Nineteen asthmatic patients, 11 with and eight without aspirin (ASA) intolerance were studied in order to test possible platelet and coagulation system involvement in the pathogenesis of aspirin-induced bronchoconstriction (AIB)." | 3.67 | Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics. ( Bednarowicz, A; Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1987) |
| "Since inhibition of cyclooxygenase precipitates asthmatic attacks in patients with aspirin idiosyncrasy, we have evaluated the effects of pharmacologic inhibition of thromboxane A2 (TXA2) synthetase, next to cyclooxygenase enzyme in arachidonic acid cascade." | 3.67 | Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma. ( Dworski, R; Gajewski, P; Nizankowska, E; Splawinska, B; Splawinski, J; Szczeklik, A, 1987) |
| "A 42-year-old man with aspirin-induced asthma also developed Prinzmetal's variant angina shortly after aspirin ingestion suggesting a possible physiologic relationship between bronchospasm and coronary spasm in aspirin-sensitive patients." | 3.67 | Is coronary arterial spasm part of the aspirin-induced asthma syndrome? ( Habbab, MA; Haft, JI; Szwed, SA, 1986) |
| "Seventy-four asthmatic patients seen in a hospital were challenged with aspirin." | 3.67 | Prevalence of aspirin intolerance in asthmatics treated in a hospital. ( Castillo, JA; Picado, C, 1986) |
| "The effect of daily aspirin (ASA) administration after "desensitisation" was studied in 16 aspirin-sensitive asthmatics." | 3.67 | Clinical efficacy of aspirin in "desensitised" aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1986) |
| "Aspirin-sensitive asthma is a common and severe disorder characterized by asthmatic attacks after oral ingestion of cyclooxygenase inhibiting drugs." | 3.67 | [Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences]. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985) |
| "The pathogenesis of aspirin-sensitive asthma remains unknown." | 3.67 | Aspirin-sensitive asthma: abnormal platelet response to drugs inducing asthmatic attacks. Diagnostic and physiopathological implications. ( Ameisen, JC; Capron, A; Fournier, E; Joseph, M; Maclouf, J; Pancré, V; Tonnel, AB; Vorng, H; Wallaert, B, 1985) |
| "This study attempted to determine whether or not nasal and sinus surgery had a beneficial or deleterious effect upon the asthma of patients with nasal polyps and aspirin idiosyncrasy." | 3.67 | Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy. ( English, GM, 1986) |
| "In a study of the incidence of respiratory reaction to tartrazine, challenge tests were made with doses of 5, 25, 50, 100 and 200 mg of tartrazine and with a placebo, on forty-seven patients with asthma associated with intolerance to analgesics (ASA-Triad)." | 3.67 | Challenge tests with tartrazine in patients with asthma associated with intolerance to analgesics (ASA-Triad). A comparative study with placebo. ( Basomba, A; Campos, A; Garcia Villalmanzo, I; Morales, MC; Pelaez, A, 1985) |
| "In a group of aspirin-sensitive asthmatics we studied skin weal and flare responses to intradermal injections of compound 48/80 and histamine during oral aspirin (ASA) provocation and after ASA "desensitisation"." | 3.67 | The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
| "Twenty seven aspirin sensitive asthmatic patients were studied to determine the relationship between non-specific bronchial responsiveness to inhaled histamine and the degree of sensitivity to aspirin (aspirin threshold dose)." | 3.67 | Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1985) |
| "Ketotifen administered prior to aspirin offered protection against bronchoconstriction in 13 of 14 patients with aspirin-sensitive asthma." | 3.66 | Inhibition by ketotifen of idiosyncratic reactions to aspirin. ( Czerniawska-Mysik, G; Kuklinski, P; Serwonska, M; Szczeklik, A, 1980) |
| "The reported incidence of acute bronchospasm in patients with asthma who take aspirin varies from 2% to 28%, depending on the methods used to obtain data." | 3.66 | Analgesic-induced asthma. ( Seale, JP, 1983) |
| "Aspirin inhibits cyclo-oxygenase by an irreversible time-dependent process of inactivation; this mechanism appears to be responsible for precipitation of asthmatic attacks in about 5%-10% of adult asthmatic patients." | 3.66 | Anti-cyclo-oxygenase agents and asthma. ( Szczeklik, A, 1983) |
| " As the lipoxygenase pathway is the only operant metabolic system available for arachidonic acid in the presence of aspirin and non-steroidal anti-inflammatory drugs--and as the nonsteroidal anti-inflammatory drugs themselves stimulate mucus production--it is possible that the mechanism responsible for mucus release in aspirin-sensitive asthmatics is the formation of these lipoxygenase products." | 3.66 | Possible mechanisms underlying mucus secretion in aspirin-sensitive asthma. ( Kaliner, M; Marom, Z, 1983) |
| "Activation of complement was sought by two independent assay methods, total hemolytic complement (CH50) and C4 activation by rocket immunoelectrophoresis for C4d and C4 in plasma samples obtained from 16 aspirin-sensitive asthmatic patients and four control subjects during provocative oral aspirin challenges." | 3.66 | The absence of detectable complement activation in aspirin-sensitive asthmatic patients during aspirin challenge. ( Chenoweth, DE; Curd, JG; Pleskow, WW; Simon, RA; Stevenson, DD, 1983) |
| " An analogous mechanism may account for aspirin-induced asthma in man." | 3.66 | Evidence for lipoxygenase pathway involvement in allergic tracheal contraction. ( Burka, JF; Paterson, NA, 1980) |
| "The influence of acetylsalicylic acid (ASA) on skin response to intradermal injection of compound 48/80 and histamine was studied in order to determine whether ASA elicits any abnormalities also in the skin of asthmatics reacting with bronchoconstriction to ingestion of this drug." | 3.66 | Potentiation by acetylsalicylic acid of skin weal response to compound 48/80 in ASA-sensitive asthmatics. ( Grzelewska-Rzymowska, I; Kowalski, ML; Rozniecki, J; Szmidt, M, 1983) |
| "In order to determine the types of respiratory responses observed during aspirin-induced reactions, 50 consecutive asthmatic patients with a history of aspirin sensitivity underwent prospective oral aspirin challenges between 1979 and 1981." | 3.66 | Aspirin-sensitive rhinosinusitis/asthma: spectrum of adverse reactions to aspirin. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1983) |
| "To determine whether the different modes of action of aspirin and acetaminophen are associated with different incidences of bronchoconstriction, and whether there is cross-reactivity in terms of intolerance, selected asthmatics were challenged with both analgesics." | 3.66 | Acetaminophen and aspirin challenges in subgroups of asthmatics. ( Falliers, CJ, 1983) |
| "Aspirin and many other analgesics may be hazardous for some patients with asthma." | 3.66 | Analgesics and asthma. ( Margolis, M; Mohan, KK, 1982) |
| "Thirty aspirin-sensitive asthmatic patients underwent incremental, oral aspirin challenge until a "positive reaction" (delta FEV1 greater than or equal to 25%) occurred." | 3.66 | Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. ( Mathison, DA; Pleskow, WW; Schatz, M; Simon, RA; Stevenson, DD; Zeiger, RS, 1982) |
| "Aspirin-sensitive asthma is not well documented in children." | 3.66 | Aspirin-induced asthma in children. ( Collins-Williams, C; Tan, Y, 1982) |
| "This study undertook to determine the usefulness of tartrazine and benzoate challenge and dietary avoidance in the management of patients with chronic asthma." | 3.66 | Tartrazine and benzoate challenge and dietary avoidance in chronic asthma. ( Broder, I; Tarlo, SM, 1982) |
| " 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man." | 3.66 | Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981) |
| "Eleven patients with intrinsic asthma and aspirin sensitivity were challenged with intravenous hydrocortisone sodium succinate (Solu-Cortef; the Upjohn Co." | 3.66 | Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. ( Dajani, BM; Hamzeh, YS; Shubair, KS; Sliman, NA, 1981) |
| "Adverse reactions (urticaria, angio-edema, bronchoconstriction, purpura) to Aspirin (ASS) and food-and-drug additives such as the yellow dye tartrazine and the preservative benzoate are observed all over the world." | 3.66 | [Acetylsalicylic acid and food additive intolerance in urticaria, bronchial asthma and rhinopathy]. ( Fabro, L; Wüthrich, B, 1981) |
| "Two aspirin-sensitive asthmatic patients underwent oral aspirin challenges for investigative purposes." | 3.66 | Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. ( Mathison, DA; Simon, RA; Stevenson, DD, 1980) |
| "Since it has been suggested that aspirin-induced asthma is due to inhibition of prostaglandin (PG) biosynthesis, the present investigation was undertaken to determine whether tartrazine would display a similar profile." | 3.66 | Is tartrazine-induced asthma related to inhibition of prostaglandin biosynthesis? ( Bessot, JC; Pauli, G; Vargaftig, BB, 1980) |
| "An H1-receptor blocking antihistamine, clemastine, taken before aspirin gave complete or partial protection against flushing, rhinorrhea, cough, and headache in ten asthmatic patients with idiosyncrasy to aspirin." | 3.66 | Inhibition of idiosyncratic reactions to aspirin in asthmatic patients by clemastine. ( Serwonska, M; Szczeklik, A, 1979) |
| "Inhibition of prostaglandin (PG) biosynthesis has been proposed as a mechanism of aspirin-induced asthma." | 3.66 | Aspirin intolerance: unaltered susceptibility of platelet cyclo-oxygenase to inhibition by aspirin in vitro. ( Ciabattoni, G; Patriarca, G; Patrono, C; Pugliese, F; Schiavino, D; Venuti, A, 1978) |
| "In an attempt to elucidate the mechanisms involved in analgesic-induced asthma, I performed bronchial and intravenous challenge tests with indomethacin in 5 aspirin-sensitive asthmatics." | 3.66 | Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics. ( Martelli, NA, 1979) |
| " Furthermore, pathogenesis, clinical picture, treatment and prophylaxis of the "Aspirin-induced asthma" are demonstrated." | 3.66 | [Drug-induced bronchospasm (author's transl)]. ( Strumeliev, S, 1978) |
| "Nasal polypectomy is safe in patients with asthma and intolerance to aspirin." | 3.66 | Nasal polypectomy in patients with asthma and sensitivity to aspirin. ( Brown, BL; Harner, SG; Van Dellen, RG, 1979) |
| "A case report is presented demonstrating the beneficial beta2 stimulating effect of halothane in a patient with status asthmaticus unresponsive to adequate conventional therapy." | 3.66 | Halothane for status asthmaticus in the intensive care unit--a case report. ( Colaco, CM; Crago, RR; Weisbert, A, 1978) |
| "A case of an adverse reaction occurring in a 53-year-old, aspirin-sensitive asthmatic male with nasal polyps following administration of a 400-mg ibuprofen tablet is reported." | 3.66 | Cross-reactivity between aspirin and ibuprofen in an asthmatic--a case report. ( Merritt, GJ; Selle, RI, 1978) |
| "The efficacy of triamcinolone acetonide aerosol in the management of asthma in six patients with aspirin hypersensitivity was evaluated during a one-year trial." | 3.65 | Triamcinolone aerosol. Treatment of aspirin-hypersensitive asthmatic patients. ( Bone, RC; Kerby, GR; Pingleton, WW; Ruth, WE, 1977) |
| "Aspirin ingestion is likely to result in severe asthmatic attacks in patients with aspirin idiosyncrasy." | 3.65 | Inhibition of gill cilial activity and of Proteus vulgaris motility as tests for aspirin idiosyncrasy. ( Crawfurd, MD; Delaney, JC; Roberts, C, 1976) |
| "Eighteen patients with asthma and aspirin hypersensitivity have been challenged with increasing doses of aspirin, fenoprofen, ibuprofen, and dextropropoxyphene." | 3.65 | Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A; Zmuda, A, 1976) |
| "The effect of aerosolized prostaglandin F2alpha (PGF2alpha) on specific airway resistance (SRaw) has been measured in patients with common (n = 10) or aspirin-sensitive asthma (n = 5)." | 3.65 | Bronchial response to inhaled prostaglandin F2alpha in patients with common or aspirin-sensitive asthma. ( Charpin, J; Gayrard, P; Grimaud, C; Orehek, J, 1977) |
| "Bronchial reactivity to prostaglandins F2alpha (PGF2alpha), E2 (PGE2) and histamine has been studied in 27 patients with aspirin-sensitive asthma and in 28 asthmatics without this sensitivity." | 3.65 | Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma. ( Nizankowska, E; Nizankowski, R; Szczeklik, A, 1977) |
| "Levels of circulating IgE, total haemolytic complement, and components C4 and C3 were measured in 16 asthmatics with aspirin idiosyncrasy and in control subjects." | 3.65 | Complement components and IgE in patients with asthma and aspirin idiosyncrasy. ( Delaney, JC; Kay, AB, 1976) |
| "Under carefully controlled conditions, seven aspirin-intolerant asthmatic patients were challenged with oral aspirin and experienced respiratory tract reactions with a decline in forced expiratory volume in 1 sec (FEV1) ranging from 26 to 64%." | 3.65 | Oral aspirin challenges in asthmatic patients: a study of plasma histamine. ( Arroyave, CM; Bhat, KN; Stevenson, DD; Tan, EM, 1976) |
| "Investigation of 100 consecutive patients admitted for nasal polypectomy revealed only 3 patients with aspirin idiosyncrasy and asthma." | 3.65 | Aspirin idiosyncrasy in patients admitted for nasal polypectomy. ( Delaney, JC, 1976) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 3.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| "The following beliefs about aspirin sensitivity are widely held: (1) it usually is accompanied by nasal polyps." | 3.65 | Aspirin allergy: a clinical study. ( Speer, F, 1975) |
| "Patients manifesting intrinsic idiopathic rhinitis and/or asthma in association with diabetes or aspirin intolerance were studied." | 3.65 | Intrinsic asthma associated with diabetes mellitus; abnormal vascular response and glucose tolerance tests. ( Cohen, GN; Fisherman, EW, 1975) |
| "Evidence has been presented supporting the hypothesis that at least 2 different types of mechanisms may be involved in aspirin intolerance, one resulting in bronchospasm and the other producing urticaria/angioedema." | 3.65 | Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine. ( Pudupakkam, RK; Settipane, GA, 1975) |
| "The aspirin intolerance syndrome is characterized by rhinitis and/or sinusitis, nasal polyposis and asthma, with or without a history of adverse reactions, following aspirin ingestion." | 3.65 | Intolerance to aspirin. ( Casterline, CL, 1975) |
| "Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics." | 3.65 | Response of aspirin-allergic patients to challenge by some analgesics in common use. ( Smith, AP, 1971) |
| "Women who had ever reported asthma or COPD were associated with an increased diabetes risk; the multivariate RRs were 1." | 2.75 | Asthma, chronic obstructive pulmonary disease, and type 2 diabetes in the Women's Health Study. ( Buring, JE; Klevak, A; Liu, S; Manson, JE; Song, Y, 2010) |
| "Aspirin sensitivity was confirmed by either intranasal or oral aspirin challenge." | 2.73 | Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases. ( Borja, J; Fraj, J; Izquierdo, I; Pérez, I; Picado, C; Valero, A; Vives, R, 2008) |
| " One hundred twenty-seven subjects with history of adverse reaction to ASA/NSAIDs received oral challenges with nimesulide, 61 subjects were challenged with meloxicam, 51 subjects were challenged with rofecoxib, and 37 subjects were challenged with all three drugs." | 2.71 | Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib. ( Bavbek, S; Celik, G; Misirligil, Z; Mungan, D; Ozer, F, 2004) |
| "A 4-week trial of 30 patients with bronchial asthma." | 2.69 | [A complex evaluation of the efficacy of aldecin in treating bronchial asthma patients]. ( Arkhipova, SV; Kakhnovskiĭ, IM; Marinin, VF; Sorokina, LA, 1998) |
| "The lysine-ASA challenge was highly reproducible (geometric mean for group PD20 being identical for the open prestudy and the placebo session), and was associated with a post-challenge increase in urinary LTE4." | 2.67 | The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics. ( Blomqvist, H; Dahlén, B; Dahlén, SE; Kumlin, M; Larsson, C; Margolskee, DJ; Williams, VC; Zetterström, O, 1993) |
| "Chronic rhinosinusitis is often associated with bronchial asthma." | 2.45 | [Chronic rhinosinusitis in morbus widal: clinical aspects and therapeutic options]. ( Jung, H, 2009) |
| " Off-label long-term use of COX2 inhibitors in patients with a history of colorectal adenomas in well-designed, placebo-controlled trials showed that treatment with these agents is associated with an increased rate of cardiovascular adverse effects." | 2.44 | Drug insight: cyclo-oxygenase-2 inhibitors--a critical appraisal. ( Brune, K; Hinz, B; Renner, B, 2007) |
| "Aspirin was introduced into medicine over a century ago and has become the most popular drug in the world." | 2.43 | The broken balance in aspirin hypersensitivity. ( Sanak, M; Szczeklik, A, 2006) |
| "Sinusitis is very common, so it is important to understand its pathophysiology, diagnosis, and medical and surgical treatments." | 2.43 | Sinusitis: allergies, antibiotics, aspirin, asthma. ( Radojicic, C, 2006) |
| "Nasal polyps are as common as adult onset asthma and unilateral polyps require histological examination." | 2.42 | Nasal polyps. ( Drake-Lee, AB, 2004) |
| "Bronchial asthma is not a homogenous disease." | 2.41 | Diagnosis, prevention and treatment of aspirin-induced asthma and rhinitis. ( Bánska, K; Bochenek, G; Nizankowska, E; Szabó, Z; Szczeklik, A, 2002) |
| "Aspirin was discovered by Gerhardt in 1853." | 2.40 | [Asthma and aspirin]. ( Sonneville, A, 1998) |
| "Aspirin was discovered by Gerhardt in 1853." | 2.40 | Current synthetic notions on aspirin induced asthma. ( Sonneville, A, 1999) |
| "Treatment of the nasal polyps has been shown to improve the patients' asthma." | 2.38 | Nasal polyps, bronchial asthma and aspirin sensitivity. ( Hawke, M; Jeney, E; Probst, L; Stoney, P, 1992) |
| "Bronchial asthma is characterized by airways inflammation and airways hyperresponsiveness." | 2.38 | Sulphidopeptide leukotrienes in asthma. ( Arm, JP; Christie, P; Crea, AE; Hawksworth, RJ; Jacques, C; Lee, TH; O'Hickey, SP; Spur, BW, 1991) |
| "Some particular cases of bronchial asthma are improved by acetylsalicylic acid." | 2.38 | [Asthma relieved by aspirin]. ( Frans, A; Garin, P, 1989) |
| "Aspirin sensitivity has a highly significant association with AFRS." | 1.48 | Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study. ( Ahmed, S; Almeyda, R; Anari, S; Carrie, S; Cathcart, R; Clark, A; Coombes, E; Erskine, S; Farboud, A; Hobson, J; Hopkins, C; Jervis, P; Kara, N; Khalil, H; Kumar, N; Mansell, N; Panesaar, J; Philpott, C; Philpott, CM; Prinsley, P; Ray, J; Robertson, A; Salam, M; Sunkaraneni, S; Sunkaraneni, V; Wilson, A; Woods, J, 2018) |
| "In patients with bronchial asthma tolerant to aspirin, platelet activation factor did not induce chemiluminescence irrespective of incubation with acetylsalicylic acid." | 1.46 | Acetylsalicylic Acid Produces Different Effects on the Production of Active Oxygen Species by Activated Platelets in Different Inflammatory Diseases. ( Gabbasov, ZA; Kagan, LG; Kogan-Yasny, VV; Lakhno, DA; Ryzhkova, EV; Shpektor, AV; Vasilieva, EY, 2017) |
| "Most bronchial and naso-ocular reactions during oral aspirin challenges occurred within a narrow dosing range (45-100 mg)." | 1.35 | Rational approach to aspirin dosing during oral challenges and desensitization of patients with aspirin-exacerbated respiratory disease. ( Hope, AP; Simon, RA; Stevenson, DD; Woessner, KA, 2009) |
| " Pharmacokinetic studies showed that montelukast bioavailability is not affected by food and did not interact with other drugs." | 1.31 | Dose selection and dosing interval determination for LTRA use in asthma. ( Hendeles, L, 2000) |
| "Aspirin sensitivity was established previously in all six patients during a prior ASA oral challenge." | 1.31 | Lack of effect of the 5-lipoxygenase inhibitor zileuton in blocking oral aspirin challenges in aspirin-sensitive asthmatics. ( Daffern, PJ; Pauls, JD; Simon, RA; Stevenson, DD, 2000) |
| "Montelukast pretreatment was generally not effective in altering upper airway reactions and only partly effective in altering lower airway reactions." | 1.31 | Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics. ( Christiansen, SC; Mathison, DA; Simon, RA; Stevenson, DD, 2000) |
| "Those having analgesic intolerance and bronchial asthma were accepted as group I; patients having only asthma were accepted as group II." | 1.30 | Occurrence of allergic conditions in asthmatics with analgesic intolerance. ( Bariş, YI; Kalyoncu, AF; Karakaya, G; Sahin, AA, 1999) |
| " Neither differences in bioavailability of ASA nor the formation of SA seems to contribute to the aspirin-elicited reactions." | 1.29 | Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects. ( Anderson, P; Andersson, R; Boréus, LO; Dahlén, B; Zetterström, O, 1994) |
| "The cause of nasal polyps is speculative." | 1.29 | [The viral and allergic origin of nasal polyposis]. ( Braun, W; Bürkle, H; Klima, A; May, A, 1993) |
| "Flurbiprofen (Ansaid) is a newly released nonsteroidal antiinflammatory drug (NSAID) that is a potent inhibitor of prostaglandin synthesis." | 1.28 | Flurbiprofen (Ansaid) cross-sensitivity in an aspirin-sensitive asthmatic patient. ( Bosso, JV; Creighton, D; Stevenson, DD, 1992) |
| "Both prednisolone and aspirin were administered with improvement of eosinophilia and partial thrombolysis." | 1.28 | [A case of hypereosinophilic syndrome followed by bronchial asthma, intraventricular thrombus, and duodenitis]. ( Aoi, K; Doi, I; Hiraga, T; Kawakami, Y; Munakata, M; Ohtsuka, Y, 1991) |
| "A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital." | 1.28 | [Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991) |
| "The inhalation challenge with lysine-aspirin (L-ASA) using the dosimeter method allows the construction of a dose-response curve and the quantitative estimation of airway responsiveness to the drug." | 1.28 | Aspirin-induced asthma and bronchial hyperresponsiveness. ( Cocco, G; Masi, C; Melillo, E; Melillo, G; Padovano, A, 1991) |
| "Arterial hypertension was found in 78 of 224 consecutive patients operated for nasal polyposis." | 1.28 | Nasal polyposis as a risk factor for hypertension. ( Granström, G; Jacobsson, E; Jeppsson, PH, 1990) |
| "Tissue eosinophilia is regulated by chemical attractants and activating substances of various origins and plays a major part in the chronic inflammatory state." | 1.28 | Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin. ( Guyot, JL; Hsieh, V; Maria, Y; Moneret-Vautrin, DA; Mouton, C; Wayoff, M, 1990) |
| "Bronchial asthma was diagnosed in 40% of all patients." | 1.28 | Recurrence of nasal polyps after surgical treatment. ( Holopainen, E; Jäntti-Alanko, S; Malmberg, H, 1989) |
| "of our patients with bronchial asthma." | 1.27 | [Inhalation provocation test with lysine acetylsalicylic acid (Aspisol)--a useful method for the diagnosis of analgesic asthma]. ( Kirsten, D; Meister, W; Treutler, D, 1984) |
| "Aspirin challenge was negative to 650 mg and 3250 mg in 18/18 and 8/8 patients respectively." | 1.27 | Primary nasal polyposis. ( Culver, WG; Freda, AJ; Jacobs, RL, 1983) |
| "Aspirin intolerance has become increasingly important in clinical dermatology during the past decade, especially as a diagnostic aid in chronic urticaria." | 1.27 | [Clinical and pathogenetic aspects of aspirin intolerance]. ( Voigtländer, V, 1986) |
| "Maxillofacial pain is often managed by the use of mild analgesics, such as acetylsalicylic acid and nonsteroidal anti-inflammatory agents." | 1.27 | Aspirin-intolerance syndrome. Report of a case. ( Fridrich, HH; Fridrich, KL; Zach, GA, 1986) |
| "Although 40% had bronchial asthma, only 16." | 1.27 | ASA disease: the clinical relationship of nasal polyposis to ASA intolerance. ( Di Rienzo, V; Fais, G; Nucera, E; Patriarca, G; Romano, A; Schiavino, D; Venuti, A, 1986) |
| "In 97." | 1.26 | [Hypersensitivity to acetysal in bronchial asthma]. ( Kosturkov, G; Mileva, Zh; Staneva-Stoianova, M, 1980) |
| "Prevention of arterial hypoxemia by oxygen breathing blocked an increase in pulmonary vascular resistance in four pretreated responders." | 1.26 | Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors. ( Baier, H; Cohn, MA; Wanner, A, 1978) |
| "Among adult patients with bronchial asthma and/or allergic rhinitis undergoing allergological investigation with skin test, nasal provocation test and RAST, 1129 answered a questionaire regarding food sensitivity (FS)." | 1.26 | Food sensitivity reported by patients with asthma and hay fever. A relationship between food sensitivity and birch pollen-allergy and between food sensitivity and acetylsalicylic acid intolerance. ( Eriksson, NE, 1978) |
| "bronchial asthma caused by allergy, 2." | 1.26 | [Classification of bronchial asthma]. ( Kersten, W; Worth, G, 1977) |
| "Nasal polyps were twice as common in men as women, though a woman with nasal polyps was twice as likely to have asthma as a man." | 1.26 | Nasal polyps, nasal polypectomy, asthma, and aspirin sensitivity. Their association in 445 cases of nasal polyps. ( Moloney, JR, 1977) |
| " In the uncommon occurrence of asthma and diabetes in the same patient, insulin dosage should be considered as a factor in all such asthmatics who do not respond well to conventional therapy." | 1.26 | Diabetes mellitus and insulin in an aspirin sensitive asthmatic. ( Caplin, I, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 475 (39.16) | 18.7374 |
| 1990's | 247 (20.36) | 18.2507 |
| 2000's | 340 (28.03) | 29.6817 |
| 2010's | 117 (9.65) | 24.3611 |
| 2020's | 34 (2.80) | 2.80 |
| Authors | Studies |
|---|---|
| Sadanandam, YS | 1 |
| Shetty, MM | 1 |
| Rao, AB | 1 |
| Rambabu, Y | 1 |
| Wallace, DV | 1 |
| Ramos, CL | 1 |
| Woessner, KM | 7 |
| Sanak, M | 31 |
| Bentabol-Ramos, G | 1 |
| Saenz de Santa Maria-Garcia, R | 1 |
| Vidal-Diaz, M | 1 |
| Eguiluz-Gracia, I | 1 |
| Testera-Montes, A | 1 |
| Suikkila, A | 1 |
| Lyly, A | 1 |
| Hafrén, L | 2 |
| Saarinen, R | 2 |
| Klockars, T | 1 |
| Aydin, Ö | 4 |
| Atmiş, EÖ | 1 |
| Anadolu, Y | 1 |
| Yorulmaz, İ | 2 |
| Çelik, GE | 5 |
| Walters, BK | 1 |
| Hagan, JB | 1 |
| Divekar, RD | 1 |
| Willson, TJ | 1 |
| Stokken, JK | 1 |
| Pinheiro-Neto, CD | 1 |
| O'Brien, EK | 1 |
| Choby, G | 1 |
| Esmaeilzadeh, H | 1 |
| Zare, M | 1 |
| Alyasin, S | 1 |
| Nabavizadeh, H | 1 |
| Mortazavi, N | 1 |
| Kanannejad, Z | 1 |
| Güloğlu, D | 2 |
| Seçil, D | 2 |
| Melli, M | 4 |
| Doğu, F | 2 |
| Ikinciogullari, A | 2 |
| Sin, BA | 2 |
| Demirel, Y | 2 |
| Misirligil, Z | 9 |
| Schneider, S | 1 |
| Poglitsch, K | 1 |
| Morgenstern, C | 1 |
| Quint, T | 1 |
| Gangl, K | 1 |
| Sinz, C | 1 |
| Bartosik, T | 1 |
| Campion, NJ | 1 |
| Liu, DT | 1 |
| Landegger, LD | 1 |
| Tu, A | 1 |
| Stanek, V | 1 |
| Rocha-Hasler, M | 1 |
| Bangert, C | 1 |
| Eckl-Dorna, J | 1 |
| Karakaya, G | 4 |
| Erkekol, FO | 2 |
| Dursun, AB | 4 |
| Gelincik, A | 2 |
| Damadoglu, E | 2 |
| Yucel, T | 2 |
| Dursun, E | 2 |
| Buyukatalay, ZC | 1 |
| Sozener, ZC | 1 |
| Buyukozturk, S | 2 |
| Kalyoncu, AF | 4 |
| Stevens, WW | 1 |
| Cahill, KN | 5 |
| Tuncay, G | 1 |
| Cihanbeylerden, M | 1 |
| Can Bostan, O | 1 |
| Kayıkcı, H | 1 |
| Özer, S | 1 |
| Fathollahpour, A | 1 |
| Abyaneh, FA | 1 |
| Darabi, B | 1 |
| Ebrahimi, M | 1 |
| Kooti, W | 2 |
| Kalmarzi, RN | 2 |
| Alfallaj, R | 1 |
| Obaid, SB | 1 |
| Almousa, H | 1 |
| Ismail, D | 1 |
| Mahjoub, S | 1 |
| Alanazy, F | 1 |
| Dousary, SA | 1 |
| Alromaih, S | 1 |
| Aloulah, M | 1 |
| Alrasheed, A | 1 |
| Alroqi, AS | 1 |
| Alsaleh, S | 1 |
| Sánchez, J | 1 |
| García, E | 1 |
| Lopez, JF | 1 |
| Calle, A | 1 |
| Buendia, JA | 1 |
| Mullur, J | 1 |
| Buchheit, KM | 2 |
| Lee, Y | 1 |
| Kim, C | 1 |
| Lee, E | 1 |
| Lee, HY | 5 |
| Woo, SD | 1 |
| You, SC | 1 |
| Park, RW | 1 |
| Park, HS | 42 |
| Adame, MJ | 1 |
| Raji, M | 1 |
| Shan, Y | 1 |
| Zhang, Y | 1 |
| Kuo, YF | 1 |
| Tripple, JW | 1 |
| Imam, KH | 1 |
| Foer, D | 1 |
| Amin, T | 1 |
| Nagai, J | 1 |
| Tani, Y | 1 |
| Feng, C | 2 |
| Liu, T | 2 |
| Newcomb, DC | 1 |
| Lai, J | 2 |
| Hayashi, H | 2 |
| Snyder, WE | 1 |
| McGill, A | 1 |
| Lin, A | 1 |
| Laidlaw, TM | 5 |
| Niswender, KD | 1 |
| Boyce, JA | 3 |
| Eid, RC | 1 |
| Palumbo, ML | 1 |
| Wongsa, C | 1 |
| Sompornrattanaphan, M | 1 |
| Tantilipikorn, P | 1 |
| Thongngarm, T | 1 |
| Podwysocka, M | 1 |
| Dąbrowska, K | 1 |
| Fendler, W | 1 |
| Pagacz, K | 1 |
| Pietruszewska, W | 1 |
| Nelson, RK | 1 |
| Bush, A | 1 |
| Stokes, J | 1 |
| Nair, P | 1 |
| Akuthota, P | 2 |
| McHugh, T | 1 |
| Levin, M | 1 |
| Snidvongs, K | 1 |
| Banglawala, SM | 1 |
| Sommer, DD | 2 |
| Vandenberghe-Dürr, S | 1 |
| Landis, BN | 1 |
| Jandus, P | 1 |
| Gelardi, M | 1 |
| Porro, G | 1 |
| Quaranta, V | 1 |
| Quaranta, N | 1 |
| Cassano, M | 1 |
| Ciprandi, G | 1 |
| Study Group On CRSwNP, I | 1 |
| Jakiela, B | 1 |
| Soja, J | 8 |
| Sladek, K | 8 |
| Przybyszowski, M | 1 |
| Plutecka, H | 4 |
| Gielicz, A | 7 |
| Rebane, A | 1 |
| Bochenek, G | 16 |
| Cameli, P | 1 |
| D'Alessandro, M | 1 |
| Bergantini, L | 1 |
| Silvestri, E | 1 |
| Romaldi, A | 1 |
| Emmi, G | 1 |
| Parronchi, P | 1 |
| Bargagli, E | 1 |
| Bhat, TA | 1 |
| Kalathil, SG | 1 |
| Miller, A | 1 |
| Thatcher, TH | 1 |
| Sime, PJ | 1 |
| Thanavala, Y | 1 |
| Bergmark, RW | 1 |
| Palumbo, M | 1 |
| Rahman, S | 1 |
| Maurer, R | 1 |
| Dominas, C | 1 |
| Roditi, R | 1 |
| Bhattacharyya, N | 1 |
| Maxfield, A | 1 |
| Eraso, I | 1 |
| Sangiovanni, S | 1 |
| Morales, EI | 1 |
| Fernández-Trujillo, L | 1 |
| Ball, LL | 1 |
| Velasquez, SA | 1 |
| Al Jammal, OM | 1 |
| White, AA | 3 |
| Mitsui, C | 1 |
| Kajiwara, K | 2 |
| Ono, E | 4 |
| Watai, K | 1 |
| Kamide, Y | 1 |
| Fukutomi, Y | 3 |
| Sekiya, K | 3 |
| Tsuburai, T | 2 |
| Yamamoto, K | 4 |
| Taniguchi, M | 20 |
| De Corso, E | 1 |
| Lucidi, D | 1 |
| Battista, M | 1 |
| Romanello, M | 1 |
| De Vita, C | 1 |
| Baroni, S | 1 |
| Autilio, C | 1 |
| Galli, J | 1 |
| Paludetti, G | 1 |
| Smith, LJ | 2 |
| Park, H | 1 |
| Choi, Y | 1 |
| Jung, CG | 1 |
| Gabbasov, ZA | 1 |
| Kogan-Yasny, VV | 1 |
| Lakhno, DA | 1 |
| Kagan, LG | 1 |
| Ryzhkova, EV | 1 |
| Vasilieva, EY | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study of the Effects of the Selective CysLT1 Antagonist Montelukast on Bronchoconstriction and Airway Inflammation Induced by Inhalation of Leukotriene E4 in Subjects With Asthma[NCT01841164] | 14 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| A Retrospective Epidemiological Study to Map Out Patients With Chronic Obstructive Pulmonary Disease (COPD) and Describe COPD Health Care in Real-Life Primary Care During the First Ten Years of the 21th Century[NCT01146392] | 27,394 participants (Actual) | Observational | 2010-06-30 | Completed | |||
| Moving Towards PREcision Medicine In United Airways Disease: Unraveling inflaMmatory Patterns in Asthmatic Patients With or Without Nasal Polyps (PREMIUM) - a Descriptive Pilot Study[NCT05009758] | 30 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | |||
| A 12-Month, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma[NCT01287039] | Phase 3 | 489 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| A 12-Month, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma[NCT01285323] | Phase 3 | 464 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| Dupilumab as add-on Therapy for Aspirin-exacerbated Respiratory Disease (AERD)[NCT03595488] | Phase 2 | 11 participants (Actual) | Interventional | 2018-09-05 | Completed | ||
| The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases[NCT01867281] | Phase 4 | 32 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615] | 50 participants (Anticipated) | Interventional | 2012-09-30 | Not yet recruiting | |||
| Improving Patient Care Via Proteomics Based, Microbe-Specific Detection of Chronic Rhinosinusitis[NCT00962689] | 38 participants (Actual) | Observational | 2009-08-31 | Completed | |||
| Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis[NCT03472144] | Phase 3 | 60 participants (Anticipated) | Interventional | 2017-07-07 | Recruiting | ||
| Double Blind Study to Determine Effect of Omalizumab Treatment in Patients With the Co-Morbid Conditions of Aspirin Exacerbated Respiratory Disease(AERD) and Allergic Asthma and Rhinitis.[NCT00286416] | 60 participants | Interventional | 2006-01-31 | Recruiting | |||
| Pilot Study of the Effect of Omalizumab on Basophil and Mast Responses to Intranasal Cat Allergen Challenge[NCT00604786] | 18 participants (Actual) | Interventional | 2007-07-31 | Completed | |||
| Role of Doxycycline in the Management of Patients With Chronic Rhinosinusitis With Nasal Polyps[NCT05157412] | Phase 3 | 60 participants (Anticipated) | Interventional | 2022-03-01 | Not yet recruiting | ||
| Retrospective Review on Patients With Recurrent Asthmatic Attacks Requiring Hospitalizations[NCT04479501] | 2,280 participants (Actual) | Observational | 2017-12-01 | Completed | |||
| A 3 Year Longitudinal Study of the Level of Asthma Control and Treatment of Asthma Patients in Hong Kong[NCT03239431] | 400 participants (Anticipated) | Observational [Patient Registry] | 2017-09-15 | Recruiting | |||
| Effect of Thymoquinone and Olive Oil on Wound Healing After Endoscopic Sinus Surgery in Patients With Nasal Polyposis[NCT06070311] | 50 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | |||
| Role of Short Term Systemic Corticosteroid Therapy in the Management of Chronic Rhinosinusitis Without Nasal Polyps[NCT01676415] | Phase 4 | 9 participants (Actual) | Interventional | 2012-08-31 | Terminated (stopped due to participants are no longer receiving intervention due to clinical logistics) | ||
| High Volume Saline Irrigation in the Post-operative Management of Chronic Rhinosinusitis: A Multicenter Randomized Single-Blind Controlled Trial[NCT02636959] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | ||
| Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP). Can Shedding of Epithelial Barrier Proteins be Used as Biomarker in Severe Asthma With/Out CRSwNP Manageme[NCT05365841] | 85 participants (Anticipated) | Observational | 2022-05-15 | Not yet recruiting | |||
| Ideal Frequency of Postoperative High Volume Saline Irrigations Following Endoscopic Sinus Surgery[NCT01680705] | 75 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479] | Phase 3 | 39,876 participants (Actual) | Interventional | 1992-09-30 | Completed | ||
| Predicting the Bronchoprotective Response to a Leukotriene Modifier by Genetic Polymorphism[NCT00116324] | Phase 3 | 150 participants | Interventional | 2003-04-30 | Completed | ||
| 'The Factors Associated With the Formation of Nasal Polyp'[NCT01278719] | 180 participants (Anticipated) | Observational | 2010-01-31 | Recruiting | |||
| Effects of Anti-IgE Antibody Omalizumab (Xolair) on Patients With Chronic Sinusitis and a Positive Allergen Test[NCT00117611] | Phase 4 | 14 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| Prospective Observational Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With Reslizumab[NCT03369574] | 0 participants (Actual) | Observational | 2017-11-14 | Withdrawn (stopped due to Study personnel diverted to other activities and the study was not commenced) | |||
| The Efficacy of Debridement of the Sinus Cavity Following Primary Functional Endoscopic Sinus Surgery (FESS): A Randomized Controlled Trial.[NCT04093193] | 150 participants (Anticipated) | Interventional | 2018-06-22 | Recruiting | |||
| Randomized, Double-blinded, Placebo-controlled, Prospective, Multicenter Trial to Evaluate the Efficacy and Safety of SIC in Subjects With Mild/Moderate Asthma and Rhinitis/Rhinoconjunctivitis Sensitized to D.Pteronyssinus and/or D. Farinae[NCT04435990] | Phase 3 | 150 participants (Anticipated) | Interventional | 2020-10-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The ACQ is a 7-item instrument that measures asthma control (Juniper et al 1999). Six questions are self-assessments; the seventh item, completed by a member of the study staff, is the result of the patient's FEV1 measurement. Each item has 7 possible answers on a scale of 0 to 6, and the total score is the mean of all responses (the total scale is therefore 0-6). A higher score is an indication of poorer asthma control. The during treatment (Weeks 4, 8, 12 and 16) average ACQ was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Negative change from baseline scores indicate improvement in asthma control." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | -0.676 |
| Reslizumab 3.0 mg/kg | -0.941 |
"The AQLQ is a 32-item instrument administered as a self-assessment (Juniper et al 1992). The questionnaire is divided into 4 domains: activity limitation, symptoms, emotional function, and environmental stimuli. Patients were asked to recall their experiences during the last 2 weeks and to respond to each question on a 7-point scale (1=severe impairment, 7=no impairment). The overall AQLQ score is the mean of all 32 responses. Five of the activity questions were patient-specific, which means that each patient identified and scored 5 activities in which the patient was limited by asthma; these 5 activities were identified at the first visit and retained for all subsequent follow-up visits.~Positive change from baseline scores indicate improvement in quality of life." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Week 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 0.695 |
| Reslizumab 3.0 mg/kg | 0.933 |
"The ASUI is an 11-item instrument designed to assess the frequency and severity of asthma symptoms and side effects, weighted by patient preferences (Revicki et al 1998). ASUI is a utility score that ranges from 0 to 1, with higher values indicating better asthma control; info obtained from questionnaire about asthma symptoms.~The during treatment (Weeks 4, 8, 12 and 16) average ASUI was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Positive change from baseline values indicate improvement in asthma symptoms. Information was obtained from questionnaire about asthma symptoms." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 0.109 |
| Reslizumab 3.0 mg/kg | 0.167 |
"FEV1 is a standard measurement of air movement in the lungs of patients with asthma obtained from pulmonary function tests. It is the volume of air expired in the first second of a forced expiration using a spirometer. Positive change from baseline scores indicate improvement in asthma control.~The during treatment (Weeks 4, 8, 12 and 16) average FEV1 was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12 and 16
| Intervention | liters (Least Squares Mean) |
|---|---|
| Placebo | 0.110 |
| Reslizumab 3.0 mg/kg | 0.248 |
"SABA are used for quick relief of asthma symptoms. To measure SABA use, at each clinical visit patients were asked to recall their usage of SABA therapy within the last 3 days of the scheduled visit. If usage was confirmed, the number of puffs used was recorded. For the purpose of summaries, an average daily usage was evaluated by dividing the total number of puffs recorded over 3 days by 3.~The during treatment (Weeks 4, 8, 12 and 16) SABA use was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Negative change from baseline scores indicate improvement in asthma control." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | puffs/day (Least Squares Mean) |
|---|---|
| Placebo | -0.36 |
| Reslizumab 3.0 mg/kg | -0.64 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization CAEs were adjudicated by committee to assure consistency.~Adjusted CAE rate and confidence intervals were based on Negative Binomial regression model adjusted for stratification factors.~Results are offered as adjusted means." (NCT01287039)
Timeframe: Day 1 to Week 52
| Intervention | CAEs in 52 weeks (Mean) |
|---|---|
| Placebo | 1.804 |
| Reslizumab 3.0 mg/kg | 0.904 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization.~CAEs were adjudicated by committee to assure consistency. The distributions were compared by a log rank test stratified by baseline usage of oral corticosteroid (yes or no) and geographical region (US or other)." (NCT01287039)
Timeframe: Day 1 to Day 478 (longest treatment time plus 2 weeks)
| Intervention | weeks (Median) |
|---|---|
| Placebo | 34.9 |
| Reslizumab 3.0 mg/kg | NA |
The immunogenicity of reslizumab was assessed by measuring for the presence of anti-reslizumab antibodies at baseline, weeks 16, 32, 48, and 52 or early withdrawal. Blood samples for anti-reslizumab antibodies assessment were also obtained from all patients (inside or outside of the US) experiencing a serious adverse event, an adverse event leading to withdrawal, or an exacerbation of asthma symptoms. (NCT01287039)
Timeframe: Weeks 16, 32, 48 and 52
| Intervention | participants (Number) |
|---|---|
| Reslizumab 3.0 mg/kg | 8 |
"Blood eosinophil counts were measured using a standard complete blood count (CBC) with differential blood test at each scheduled visit, and from all patients experiencing a serious adverse event, an adverse event leading to withdrawal, or an exacerbation of asthma symptoms.~The during treatment average eosinophil counts were estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Negative change from baseline values correlate to reduced asthma severity." (NCT01287039)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52 or early withdrawal
| Intervention | 10^9 blood eosinophil/L (Least Squares Mean) | |
|---|---|---|
| Over first 16 weeks | Over 52 weeks | |
| Placebo | -0.118 | -0.127 |
| Reslizumab 3.0 mg/kg | -0.584 | -0.582 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization.~CAEs were adjudicated by committee to assure consistency. Adjusted CAE rate and confidence intervals for the two criteria were based on Negative Binomial regression model adjusted for stratification factors.~Results are offered as adjusted means." (NCT01287039)
Timeframe: Day 1 to Week 52
| Intervention | CAEs in 52 weeks (Mean) | |
|---|---|---|
| Requiring systemic corticosterioids >3 days | Requiring hospitalization or ER visit | |
| Placebo | 1.604 | 0.207 |
| Reslizumab 3.0 mg/kg | 0.722 | 0.137 |
An adverse event was defined in the protocol as any untoward medical occurrence that develops or worsens in severity during the conduct of a clinical study and does not necessarily have a causal relationship to the study drug. Severity was rated by the investigator on a scale of mild, moderate and severe, with severe= an inability to carry out usual activities. Relation of AE to treatment was determined by the investigator. Serious AEs include death, a life-threatening adverse event, inpatient hospitalization or prolongation of existing hospitalization, persistent or significant disability or incapacity, a congenital anomaly or birth defect, OR an important medical event that jeopardized the patient and required medical intervention to prevent the previously listed serious outcomes. (NCT01287039)
Timeframe: Day 1 (post-dose) to Week 65. The last postbaseline value for approximately 20 patients in each
| Intervention | participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| At least 1 AE | Mild severity AE | Moderate severity AE | Severe AE | Treatment-related AE | Treatment-related mild AE | Treatment-related moderate AE | Treatment-related severe AE | AE causing patient discontinuation | Serious AE | Deaths | |
| Placebo | 206 | 41 | 133 | 32 | 36 | 23 | 13 | 0 | 8 | 34 | 1 |
| Reslizumab 3.0 mg/kg | 197 | 68 | 107 | 22 | 36 | 24 | 9 | 3 | 4 | 24 | 0 |
"Data represents participants with potentially clinically significant (PCS) abnormal serum chemistry, hematology, and urinalysis values.~Significance criteria:~Blood urea nitrogen: >=10.71 mmol/L~Uric acid: M>=625, F>=506 μmol/L~Aspartate aminotransferase: >=3*upper limit of normal (ULN). Normal range is 10-43 U/L~Alanine aminotransferase: >=3*ULN. Normal range is 10-40 U/L~GGT = gamma-glutamyl transpeptidase: >= 3*ULN. Normal range is 5-49 U/L.~Bilirubin: >=34.2 μmol/L~White blood cells: <=3.0 or >20 10^9/L~Hemoglobin: M<=115, F<=95 g/dL~Hematocrit: M<0.37, F<0.32 L/L~Neutrophils: <=1.0 10^9/L~Eosinophils: >10.0 %~Platelets: <75 or >=700 10^9/L~Urinalysis: blood, glucose, ketones and total protein: >=2 unit increase from baseline" (NCT01287039)
Timeframe: Week 4 to Week 65. The last postbaseline value for approximately 20 patients in each
| Intervention | participants (Number) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood urea nitrogen | Uric acid | Aspartate aminotransferase | Alanine aminotransferase | Gamma-glutamyl transpeptidase | Bilirubin | White blood cells - low | White blood cells - high | Hemoglobin | Hematocrit | Neutrophils | Eosinophils | Platelets - low | Platelets - high | Urinalysis - Blood (hemoglobin) | Urinalysis - Ketones | Urinalysis - Glucose | Urinalysis - Protein | |
| Placebo | 9 | 9 | 1 | 3 | 12 | 2 | 6 | 5 | 7 | 9 | 8 | 135 | 1 | 2 | 32 | 4 | 11 | 32 |
| Reslizumab 3.0 mg/kg | 8 | 6 | 1 | 5 | 12 | 1 | 6 | 3 | 4 | 6 | 6 | 3 | 2 | 0 | 21 | 5 | 14 | 34 |
"Data represents participants with potentially clinically significant (PCS) vital sign values.~Significance criteria~Sitting pulse - high 12-17 yr: >100 and increase of >= 30 beats/minute (bpm)~Sitting pulse - low >=18 yr: <50 and decrease of >=30 bpm~Sitting pulse - high >=18 yr: >100 and increase of >=30 bpm~Sitting systolic blood pressure - low >=18 yr: <90 and decrease of >=30 mmHg~Sitting systolic blood pressure - high >=18 yr: >160 and increase of >=30 mmHg~Sitting diastolic blood pressure - low 12-17 yr: <55 and decrease of >=12 mmHg~Sitting diastolic blood pressure - low >=18 yr: <50 and decrease of >=12 mmHg~Sitting diastolic blood pressure - high >=18 yr: >100 and increase of >=12 mmHg~Respiratory rate >=18 yr: >24 and increase of >=10 breaths/minute~Body temperature - low 12-17 yr: <96.5° Fahrenheit or <35.8° Celsius~Body temp - low >=18 yr: <96.5° F or <35.8° C~Body temp - high >=18 yr: >100.5° Fahrenheit" (NCT01287039)
Timeframe: Week 4 to Week 65. The last postbaseline value for approximately 20 patients in each
| Intervention | participants (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sitting pulse - high 12-17 yr | Sitting pulse - low >=18 yr | Sitting pulse - high >=18 yr | Sitting systolic blood pressure - low >=18 yr | Sitting systolic blood pressure - high >=18 yr | Sitting diastolic blood pressure - low 12-17 yr | Sitting diastolic blood pressure - low >=18 yr | Sitting diastolic blood pressure - high >=18 yr | Respiratory rate >=18 yr | Body temperature - low 12-17 yr | Body temperature - low >=18 yr | Body temperature - high >=18 yr | |
| Placebo | 1 | 1 | 5 | 2 | 7 | 1 | 0 | 10 | 3 | 1 | 54 | 0 |
| Reslizumab 3.0 mg/kg | 1 | 0 | 7 | 5 | 7 | 0 | 1 | 5 | 2 | 1 | 49 | 1 |
"The ACQ is a 7-item instrument that measures asthma control (Juniper et al 1999). Six questions are self-assessments; the seventh item, completed by a member of the study staff, is the result of the patient's FEV1 measurement. Each item has 7 possible answers on a scale of 0 to 6, and the total score is the mean of all responses (the total scale is therefore 0-6). A higher score is an indication of poorer asthma control. The during treatment (Weeks 4, 8, 12 and 16) average ACQ was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Negative change from baseline scores indicate improvement in asthma control." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | -0.660 |
| Reslizumab 3.0 mg/kg | -0.857 |
"The AQLQ is a 32-item instrument administered as a self-assessment (Juniper et al 1992). The questionnaire is divided into 4 domains: activity limitation, symptoms, emotional function, and environmental stimuli. Patients were asked to recall their experiences during the last 2 weeks and to respond to each question on a 7-point scale (1=severe impairment, 7=no impairment). The overall AQLQ score is the mean of all 32 responses. Five of the activity questions were patient-specific, which means that each patient identified and scored 5 activities in which the patient was limited by asthma; these 5 activities were identified at the first visit and retained for all subsequent follow-up visits.~Positive change from baseline scores indicate improvement in quality of life." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Week 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 0.777 |
| Reslizumab 3.0 mg/kg | 0.987 |
"The ASUI is an 11-item instrument designed to assess the frequency and severity of asthma symptoms and side effects, weighted by patient preferences (Revicki et al 1998). ASUI is a utility score that ranges from 0 to 1, with higher values indicating better asthma control; info obtained from questionnaire about asthma symptoms.~The during treatment (Weeks 4, 8, 12 and 16) average ASUI was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Positive change from baseline values indicate improvement in asthma symptoms. Information was obtained from questionnaire about asthma symptoms." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 0.080 |
| Reslizumab 3.0 mg/kg | 0.115 |
"FEV1 is a standard measurement of air movement in the lungs of patients with asthma obtained from pulmonary function tests. It is the volume of air expired in the first second of a forced expiration using a spirometer.~Positive change from baseline scores indicate improvement in asthma control." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Week 16
| Intervention | liters (Least Squares Mean) |
|---|---|
| Placebo | 0.122 |
| Reslizumab 3.0 mg/kg | 0.223 |
"FEV1 is a standard measurement of air movement in the lungs of patients with asthma obtained from pulmonary function tests. It is the volume of air expired in the first second of a forced expiration using a spirometer. During study (Weeks 4, 8, 12 and 16) average value used a mixed effect model for repeated measures (MMRM) with treatment group, visit, treatment and visit interaction, and stratification factors as fixed effects and participant as a random effect. Covariates for baseline values were also included in the model; for pulmonary function test analyses, covariates for height and sex were included as well.~Positive change from baseline scores indicate improvement in asthma control." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12 and 16
| Intervention | liters (Least Squares Mean) |
|---|---|
| Placebo | 0.094 |
| Reslizumab 3.0 mg/kg | 0.187 |
"SABA are used for quick relief of asthma symptoms. To measure SABA use, at each clinical visit patients were asked to recall their usage of SABA therapy within the last 3 days of the scheduled visit. If usage was confirmed, the number of puffs used was recorded. For the purpose of summaries, an average daily usage was evaluated by dividing the total number of puffs recorded over 3 days by 3.~The during treatment (Weeks 4, 8, 12 and 16) average SABA use was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements.~Negative change from baseline scores indicate improvement in asthma control." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16
| Intervention | SABA puffs per day (Least Squares Mean) |
|---|---|
| Placebo | -0.44 |
| Reslizumab 3.0 mg/kg | -0.50 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization.~CAEs were adjudicated by committee to assure consistency. Adjusted CAE rate and confidence intervals were based on Negative Binomial regression model adjusted for stratification factors.~Results are offered as adjusted means." (NCT01285323)
Timeframe: Day 1 to Month 12
| Intervention | CAEs in 52 weeks (Mean) |
|---|---|
| Placebo | 2.115 |
| Reslizumab 3.0 mg/kg | 0.859 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization.~CAEs were adjudicated by committee to assure consistency. The distributions were compared by a log rank test stratified by baseline usage of oral corticosteroid (yes or no) and geographical region (US or other)." (NCT01285323)
Timeframe: Day 1 to Day 526 (longest treatment time plus 2 weeks)
| Intervention | weeks (Median) |
|---|---|
| Placebo | NA |
| Reslizumab 3.0 mg/kg | NA |
"The blood eosinophil counts were measured using a standard complete blood count (CBC) with differential blood test. Results of all differential blood tests conducted after randomization were blinded.~The during treatment average eosinophil count was estimated using a mixed-effect model for repeated measures (MMRM) with fixed effects (treatment, stratification factors, sex, visit, interaction of treatment and visit), covariates (height, baseline value), and patient as the random effect for the repeated measurements. The 'over 16 weeks' value used data from Weeks 4, 8, 12 and 16. The 'over 52 weeks' value used all the during study time points listed in the Time Frame field.~Negative change from baseline values correlate to reduced asthma severity." (NCT01285323)
Timeframe: Day 1 (baseline, pre-dose), Weeks 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52 or early withdrawal
| Intervention | 10^9 blood eosinophil/L (Least Squares Mean) | |
|---|---|---|
| Over first 16 weeks | Over 52 weeks | |
| Placebo | -0.076 | -0.076 |
| Reslizumab 3.0 mg/kg | -0.555 | -0.565 |
"An exacerbation event was considered a CAE if the patient met either or both of the criteria listed below and this was corroborated with at least 1 other measurement to indicate the worsening of clinical signs and symptoms of asthma:~use of systemic, or an increase in the use of inhaled, corticosteroid treatment for 3 or more days; or an increased 2 or more fold for at least 3 or more days for patient's already on corticosteroids.~asthma-related emergency treatment, such as an unscheduled visit to the physician's office or emergency room for nebulizer treatment or other urgent treatment to prevent worsening of asthma symptoms, or an asthma-related hospitalization CAEs were adjudicated by committee to assure consistency.~Adjusted CAE rate and confidence intervals for the two criteria were based on Negative Binomial regression model adjusted for stratification factors.~Results are offered as adjusted means." (NCT01285323)
Timeframe: Day 1 to Month 12
| Intervention | CAEs in 52 weeks (Mean) | |
|---|---|---|
| Requiring systemic corticosterioids >3 days | Requiring hospitalization or ER visit | |
| Placebo | 1.660 | 0.047 |
| Reslizumab 3.0 mg/kg | 0.646 | 0.033 |
Counts of participants with a positive anti-drug antibody (ADA) response during treatment is offered for the experimental treatment arm. Blood samples were collected for determination of ADAs before study drug infusion. (NCT01285323)
Timeframe: Baseline visit (prior to reslizumab exposure), Weeks 16, 32, 48 and 52
| Intervention | participants (Number) | |||||
|---|---|---|---|---|---|---|
| Baseline | Week 16 | Week 32 | Week 48 | Week 52 | >=1 positive test result | |
| Reslizumab 3.0 mg/kg | 10 | 10 | 10 | 10 | 10 | 15 |
An adverse event (AE) was defined in the protocol as any untoward medical occurrence that develops or worsens in severity during the conduct of a clinical study and does not necessarily have a causal relationship to the study drug. Severity was rated by the investigator on a scale of mild, moderate and severe, with severe= an inability to carry out usual activities. Relation of AE to treatment was determined by the investigator. Serious AEs include death, a life-threatening adverse event, inpatient hospitalization or prolongation of existing hospitalization, persistent or significant disability or incapacity, a congenital anomaly or birth defect, OR an important medical event that jeopardized the patient and required medical intervention to prevent the previously listed serious outcomes. (NCT01285323)
Timeframe: Day 1 (post-dose) to Week 65. The endpoint for adverse events was the last postbaseline observation, which included the 90 day follow-up visit.
| Intervention | participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Any TEAE | Mild TEAE | Moderate TEAE | Severe TEAE | Treatment-related AE | Mild treatment-related AE | Moderate treatment-related AE | Severe treatment-related AE | TEAE causing patient discontinuation | Deaths | Serious AEs | |
| Placebo | 201 | 36 | 140 | 25 | 27 | 14 | 13 | 0 | 9 | 0 | 23 |
| Reslizumab 3.0 mg/kg | 177 | 67 | 98 | 12 | 34 | 22 | 11 | 1 | 8 | 0 | 18 |
"Data represents participants with potentially clinically significant (PCS) abnormal serum chemistry, hematology (except for eosinophil values), and urinalysis values.~Significance criteria:~Blood urea nitrogen: >=10.71 mmol/L~Creatinine: >=177 μmol/L~Urate: M>=625, F>=506 μmol/L~Aspartate aminotransferase (AST): >=3*upper limit of normal (ULN)~Alanine aminotransferase (ALT): >=3*ULN~GGT = gamma-glutamyl transpeptidase: >= 3*ULN~Total bilirubin: >=34.2 μmol/L~White blood cells (low): <=3.0*10^9/L~White blood cells (high): >=20*10^9/L~Hemoglobin (age >=18 years): M<=115, F<=95 g/dL~Hematocrit (age >=18 years): M<0.37, F<0.32 L/L~Eosinophils/leukocytes: >=10.0%~Platelets: <=75*10^9/L~Neutrophils: <=1.0*10^9/L~Urinalysis: blood, ketones, glucose, and protein: >=2 unit increase from baseline" (NCT01285323)
Timeframe: Week 4 to Week 52
| Intervention | participants (Number) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood urea nitrogen | Creatinine | Urate | AST | ALT | GGT | Bilirubin | Leukocytes (low) | Leukocytes (high) | Hemoglobin | Hematocrit | Eosinophils/leukocytes | Platelets | Neutrophils | Urine blood (hemoglobin) | Urine ketones | Urine glucose | Urine protein | |
| Placebo | 5 | 0 | 5 | 3 | 7 | 11 | 3 | 3 | 0 | 5 | 10 | 168 | 1 | 14 | 28 | 6 | 9 | 28 |
| Reslizumab 3.0 mg/kg | 4 | 1 | 2 | 2 | 3 | 9 | 3 | 10 | 1 | 6 | 8 | 10 | 1 | 9 | 12 | 1 | 7 | 28 |
"Data represents participants with potentially clinically significant (PCS) vital sign values.~Significance criteria~Sitting pulse (high): >100 and increase of >= 30 beats/minute~Sitting systolic blood pressure (low): <90 and decrease of >= 30 mmHg~Sitting systolic blood pressure (high): >160 and increase of >= 30 mmHg~Sitting diastolic blood pressure (low): <50 and decrease of >=12 mmHg (if 12-17 years old: <55 and decrease of >=12 mmHg 0~Sitting diastolic blood pressure (high): >100 and increase of >=12 mmHg~Respiratory rate (low): <6 breaths/minute~Respiratory rate (high): >24 and increase of >=10 breaths/minute~Body temperature (low): <35.8° Celsius~Body temperature (high): >=38.1 and increase of >=1.1° Celsius" (NCT01285323)
Timeframe: Week 4 to Week 52
| Intervention | participants (Number) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| >=1 postbaseline vital sign abnormality | Sitting pulse (high) | Sitting systolic blood pressure (low) | Sitting systolic blood pressure (high) | Sitting diastolic blood pressure (low) | Sitting diastolic blood pressure (high) | Respiratory rate (low) | Respiratory rate (high) | Body temperature (low) | Body temperature (high) | |
| Placebo | 58 | 6 | 2 | 0 | 4 | 3 | 0 | 4 | 50 | 1 |
| Reslizumab 3.0 mg/kg | 49 | 6 | 1 | 1 | 3 | 4 | 1 | 5 | 39 | 0 |
"Flow cytometry in mean fluorescence units.~100%*[(3.5 month value minus baseline value)/baseline value]" (NCT00604786)
Timeframe: Change from baseline to 3.5 months
| Intervention | percentage of basophil surface IgE (Mean) |
|---|---|
| Omalizumab Subcutaneous | -95 |
| Placebo Subcutaneous | -10 |
The medication side-effect and compliance inventory is a questionnaire to evaluate the frequency and severity of common side effects associated with the medications used in this study. (NCT01676415)
Timeframe: 4-6 weeks and 3 months after initiation of treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Prednisone | 0 |
| Topical Mometasone | 0 |
Change from baseline in individual symptom severity. The taskforce symptom inventory is a visual analog scale of the severity of the 4 major symptoms making up the clinical diagnostic criteria of CRS. (NCT01676415)
Timeframe: 4-6 weeks and 3 months after initiation of treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Prednisone | 0 |
| Topical Mometasone | 0 |
"The Sino-nasal Outcome Test-22 is a validated questionnaire that measures 22 nasal and quality of life symptoms (nasal obstruction and loss of smell and taste) ranked from 0 (not a problem) to 5 (problem as bad as it can be).~Min score= 0, Max score= 110 (worst possible problem on all symptoms)~Change from baseline of the SNOT-22 score. The SNOT-22 questionnaire is a 22-item disease-specific health related quality of life instrument validated for use in chronic rhinosinusitis." (NCT01676415)
Timeframe: 4-6 weeks and 3 months after initiation of treatment
| Intervention | units on a scale (Mean) | |
|---|---|---|
| 4-6 WEEKS | 3 MONTHS | |
| Prednisone | 45.75 | 49 |
| Topical Mometasone | 34.4 | 34.4 |
(NCT00000479)
Timeframe: Average follow-up 10.1 years
| Intervention | participants (Number) | |
|---|---|---|
| Total invasive cancer | Cancer death | |
| Aspirin + Vitamin E | 716 | 152 |
| Aspirin Only | 722 | 132 |
| Both Placebos | 706 | 143 |
| Vitamin E Only | 721 | 156 |
(NCT00000479)
Timeframe: Average follow-up 10.1 years
| Intervention | Participants (Number) | |||
|---|---|---|---|---|
| Major cardiovascular event | Stroke | Myocardial infarction | Cardiovascular death | |
| Aspirin + Vitamin E | 232 | 108 | 102 | 54 |
| Aspirin Only | 245 | 113 | 96 | 66 |
| Both Placebos | 272 | 133 | 99 | 74 |
| Vitamin E Only | 250 | 133 | 94 | 52 |
222 reviews available for aspirin and Asthma, Bronchial
| Article | Year |
|---|---|
Treatment options for chronic rhinosinusitis with nasal polyps.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Aspirin; Asthma; Biological Products; Chronic Diseas | 2021 |
Updates on treatment options in aspirin exacerbated respiratory disease.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Cytokines; Humans; Sinusitis | 2022 |
Aspirin‑induced asthma: a still evolving area of basic and clinical research.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Humans; Immunity, | 2022 |
The Utility of Nasal Challenges to Phenotype Asthma Patients.
Topics: Allergens; Aspirin; Asthma; Asthma, Aspirin-Induced; Humans; Phenotype | 2022 |
Aspirin-Exacerbated Respiratory Disease and the Unified Airway: A Contemporary Review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Disease; | 2023 |
A Review of Aspirin-exacerbated Respiratory Diseases and Immunological Efficacy of Aspirin Desensitization.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Disease; Desensitization, Immunologic; Humans; Nas | 2022 |
Aspirin-Exacerbated Respiratory Disease Polymorphisms; a review study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Humans; Polymorph | 2023 |
Aspirin-exacerbated respiratory disease: Updates in the era of biologics.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Biological Products; Chronic Disease; Humans; Nasal Polyps | 2023 |
Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease: diagnosis and current management.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Humans; Nasal Poly | 2023 |
Comorbidities associated with eosinophilic chronic rhinosinusitis: A systematic review and meta-analysis.
Topics: Aspirin; Asthma; Chronic Disease; Comorbidity; Eosinophilia; Humans; Nasal Polyps; Rhinitis; Severit | 2020 |
[Widal's triad : clinical manifestations, pathophysiology and therapeutic advances].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyp | 2020 |
Aspirin desensitization in NSAID-exacerbated respiratory disease and its outcomes in the clinical course of asthma: A systematic review of the literature and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Respiratory Tract Diseases | 2021 |
Potential Biomarkers for NSAID-Exacerbated Respiratory Disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarke | 2017 |
Aspirin exacerbated respiratory disease: Current topics and trends.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arachidonic Acid; Aspirin; A | 2018 |
Heterogeneity and the origins of asthma.
Topics: Animals; Aspirin; Asthma; Cigarette Smoking; Humans; Hypersensitivity, Immediate; Microbiota; Neutro | 2018 |
Kounis syndrome induced by oral intake of aspirin: case report and literature review.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Kounis Syndrome; Mast Cells; Middle Aged; My | 2018 |
[Bronchial asthma: progress in diagnosis and treatments. Topics: IV. Subtype/particular type/comorbidities; 4. Aspirin-exacerbated respiratory disease (AERD)].
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Comorbidity; Humans; Treatment Outcome | 2013 |
Altered metabolism of prostaglandin E2 in asthma patients with aspirin hypersensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Humans; Receptors, | 2013 |
Identifying asthma triggers.
Topics: Allergens; Aspirin; Asthma; Disease Progression; Female; Gastroesophageal Reflux; Humans; Male; Prog | 2014 |
Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Clinical Trial | 2014 |
Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity.
Topics: Animals; Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Receptors, Prostaglandin E, E | 2014 |
NSAID-exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Disease Progr | 2015 |
[Hypersensitivity to acetylsalicylic acid].
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Humans; Incidence; Nasal Polyps; Rhinitis; | 2015 |
Part 9: First Aid: 2015 International Consensus on First Aid Science With Treatment Recommendations.
Topics: Airway Management; Aspirin; Asthma; Cardiopulmonary Resuscitation; Chest Pain; Emergencies; Emergenc | 2015 |
Aspirin-Exacerbated Diseases: Advances in Asthma with Nasal Polyposis, Urticaria, Angioedema, and Anaphylaxis.
Topics: Anaphylaxis; Angioedema; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hyp | 2015 |
Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis.
Topics: Adult; Antibodies, Monoclonal, Humanized; Aspirin; Asthma; Comorbidity; DNA, Catalytic; Drug Hyperse | 2015 |
The Role of Surgery in Management of Samter's Triad: A Systematic Review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Humans; | 2016 |
Chronic Rhinosinusitis and Aspirin-Exacerbated Respiratory Disease.
Topics: Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Disease Progre | 2016 |
Aspirin-exacerbated respiratory disease and current treatment modalities.
Topics: Algorithms; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, H | 2017 |
Aspirin-exacerbated respiratory disease: Prevalence, diagnosis, treatment, and considerations for the future.
Topics: Animals; Anti-Allergic Agents; Aspirin; Asthma; Desensitization, Immunologic; Diagnosis, Differentia | 2016 |
Asthma: a syndrome composed of heterogeneous diseases.
Topics: Allergens; Aspirin; Asthma; Cytokines; Eosinophils; Humans; Immunoglobulin E; Inflammation; Mast Cel | 2008 |
What do we know about the genetics of aspirin intolerance?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Genetic Markers; Hu | 2008 |
Hyperleukotrieneuria in patients with allergic and inflammatory disease.
Topics: Aspirin; Asthma; Biomarkers; Cell Movement; Drug Hypersensitivity; Eosinophils; Gene Expression Regu | 2008 |
[Aspirin and other nonsteroidal anti-inflammatory drugs hypersensitivity--mechanisms, diagnostics and treatment].
Topics: Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Hypersensiti | 2008 |
Aspirin sensitivity and desensitization for asthma and sinusitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensi | 2009 |
Leukotriene E4: perspective on the forgotten mediator.
Topics: Animals; Aspirin; Asthma; Bronchial Hyperreactivity; Drug Hypersensitivity; Histamine; Humans; Leuko | 2009 |
Gene-expression signatures of nasal polyps associated with chronic rhinosinusitis and aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Gene Expression Profiling; Humans; Nasal Po | 2009 |
Is intrinsic asthma synonymous with infection?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Female; Humans; Lung; Mal | 2009 |
[Chronic rhinosinusitis in morbus widal: clinical aspects and therapeutic options].
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Chronic Disease; Desensitization, Immunologic; Drug Hypers | 2009 |
[Allergy and intolerance to nonsteroidal antinflammatory drugs: successful desensitization in three cases].
Topics: Adult; Anaphylaxis; Angioedema; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspi | 2009 |
[Special situations in asthma].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Risk Factors | 2009 |
Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) - classification, diagnosis and management: review of the EAACI/ENDA(#) and GA2LEN/HANNA*.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Drug Hypersensitivity; Europ | 2011 |
[Asthma exacerbations: pharmacological prevention].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anti-Asthmatic Agent | 2012 |
Aural polyps in Samter's triad: case report and literature review.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Ear Diseases; Ear Neoplasms; Female; Humans; Mastoid; Middle | 2012 |
Asthma, nasal polyposis and ulcerative colitis: a new perspective.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Autoantibodies; Colitis, Ulcerative; Fibro | 2002 |
Environmental contributions to the allergic asthma epidemic.
Topics: Air Pollutants; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Disease Outbreaks; | 2002 |
Aspirin-sensitive asthma due to diffuse neuroendocrine system pathology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Neurosecretory Systems | 2002 |
Leukotriene modifiers to prevent aspirin-provoked respiratory reactions in asthmatics.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Cl | 2002 |
Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Cell | 2002 |
Update on sensitivity to nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Eruptions; Drug Hypersensitivity; Hum | 2001 |
Sensitivity to nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleedin | 2002 |
Aspirin sensitivity and urticaria.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Eruptions; Food-Drug Interactions; Hu | 2003 |
Natural history and clinical features of aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Cross Reactio | 2003 |
Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management.
Topics: Aspirin; Asthma; Humans; Lipoxygenase; Prostaglandin-Endoperoxide Synthases | 2003 |
[Intrinsic asthma].
Topics: Adult; Age of Onset; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Cyt | 2003 |
Exploring new approaches to the treatment of asthma: potential roles for lipoxins and aspirin-triggered lipid mediators.
Topics: Animals; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclooxygenase Inhibitors; Eicosanoids; Humans; Inf | 2003 |
[Asthma and aspirin].
Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; | 2003 |
Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase 2; Drug Hypersen | 2003 |
[Asthma with hypersensitivity to aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Hypersensitivity; Leukotrienes | 2003 |
The impact of rhinosinusitis on asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Common Cold; Humans; Rhinitis; Rhinitis, A | 2003 |
Diagnosis, prevention and treatment of aspirin-induced asthma and rhinitis.
Topics: Aspirin; Asthma; Cyclooxygenase Inhibitors; Humans; Leukotrienes; Prostaglandin-Endoperoxide Synthas | 2002 |
Adverse respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Desensit | 2004 |
Clinical phenotypes of asthma.
Topics: Adult; Age of Onset; Aspirin; Asthma; Child; Cyclooxygenase Inhibitors; Humans; Occupational Exposur | 2004 |
Aspirin intolerance and the cyclooxygenase-leukotriene pathways.
Topics: Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Desensiti | 2004 |
Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Cyclooxygenase Inhibitors; D | 2004 |
Nasal polyps.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bacterial Infections; Drug Hypersensitivit | 2004 |
[Aspirin-induced asthma: clinical presentation, pathogenesis and treatment].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Fibrinolytic Agents; Humans | 2004 |
Nonsteroidal anti-inflammatory drug-induced reactions and desensitization.
Topics: Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cyclooxygenas | 2004 |
Aspirin-induced asthma: clinical aspects, pathogenesis and management.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; | 2004 |
Aspirin sensitivity: implications for patients with coronary artery disease.
Topics: Algorithms; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Coron | 2004 |
Aspirin-sensitive asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans | 2005 |
[Aspirin-induced asthma (AIA)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; E | 2005 |
Pathogenesis and management of aspirin-intolerant asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchoconstriction; Drug Therapy, Combina | 2005 |
Blocking aspirin-induced bronchospasm.
Topics: Administration, Oral; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchial Spasm; Drug Administration S | 2005 |
The broken balance in aspirin hypersensitivity.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase In | 2006 |
[Physiopathology and treatment of aspirin (NSAID) intolerance].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Huma | 2006 |
Genetic markers for differentiating aspirin-hypersensitivity.
Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Genetic Ma | 2006 |
Pathogenesis of nonsteroidal antiinflammatory drug-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Male | 2006 |
[Provocation tests in the diagnosis of acetylsalicylic acid intolerance].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersen | 2005 |
Mechanisms of aspirin sensitivity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; | 2006 |
Worsening of asthma with systemic corticosteroids. A case report and review of literature.
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Glucocorticoids; Humans; Male; Methylpredni | 2006 |
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxy | 2006 |
Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements.
Topics: Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Nasal Polyps; Prevalen | 2006 |
Sinusitis: allergies, antibiotics, aspirin, asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Platelet Aggregation Inhibitors; Rhinitis, Allergic, | 2006 |
[Asthma-related diseases. Aspirin hypersensitivity].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male | 2006 |
[Difficult asthma].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Clinical and pathologic perspectives on aspirin sensitivity and asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cyclooxygenase Inhibitors | 2006 |
Selection of patients for aspirin desensitization treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Drug Hyperse | 2006 |
[Diagnosis and treatment of aspirin-induced asthma].
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; Dose-Response Relationsh | 2006 |
[Allergy to non steroidal anti-inflammatory drugs].
Topics: Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provoca | 2006 |
Asthma phenotypes.
Topics: Aspirin; Asthma; Genetic Predisposition to Disease; Genotype; Glucocorticoids; Humans; Hypersensitiv | 2007 |
Aspirin-sensitive rhinosinusitis and asthma.
Topics: Arachidonic Acid; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Infl | 2007 |
G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Genetic Variation; Humans; Inactivation, Metabolic; Leukotri | 2006 |
EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity.
Topics: Administration, Oral; Allergens; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthm | 2007 |
Medical management of rhinosinusitis comorbidities-asthma, aspirin sensitivity, gastroesophageal reflux, immune deficiencies.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Eosinophils; Gastroesophageal Reflux; Humans; Immunologic De | 2007 |
Drug insight: cyclo-oxygenase-2 inhibitors--a critical appraisal.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Cyclooxygenase 2 | 2007 |
[Drug-induced asthma].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Humans; Time Fa | 2007 |
Pharmacogenetics of aspirin-intolerant asthma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Genetic Markers; Humans; Leukotri | 2008 |
Chronic rhinosinusitis and asthma.
Topics: Aspirin; Asthma; Chronic Disease; Comorbidity; Drug Hypersensitivity; Humans; Lymphocytes; Nasal Muc | 2008 |
[Pathogenesis of aspirin-induced asthma].
Topics: Aspirin; Asthma; Humans | 2006 |
Arachidonic acid metabolites in the healthy and diseased lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchitis; Dinoprost; Dinoprostone; | 1984 |
The pathophysiology of asthma. Extrinsic influences other than immunologic.
Topics: Aerosols; Air Pollution; Aspirin; Asthma; Asthma, Exercise-Induced; Autonomic Nervous System; Cyclic | 1984 |
The antihistamines.
Topics: Administration, Topical; Aspirin; Asthma; Drug Hypersensitivity; Ethylenediamines; Histamine H1 Anta | 1980 |
Reciprocal relationship between pregnancy and pulmonary disease. State of the art.
Topics: Adrenergic beta-Agonists; Alcohol Drinking; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Infecti | 1984 |
[Untoward side effects of acetylsalicylic acid].
Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Female; Fetus; Gastrointest | 1984 |
Aspirin and allergic diseases: a review.
Topics: Aspirin; Asthma; Bronchial Spasm; Cross Reactions; Desensitization, Immunologic; Drug Hypersensitivi | 1983 |
[Bronchial asthma caused by aspirin hypersensitivity (pathomechanism and diagnostic and therapeutic problems)].
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans | 1984 |
Analgesic-antipyretic choices for children with asthma: a review of safety and risk of common preparations.
Topics: Acetaminophen; Adolescent; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Br | 1984 |
Pathophysiological basis of asthma management.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Bro | 1981 |
Prostaglandins, slow-reacting substances (leukotrienes) and the lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchi; Epoprostenol; Guinea Pigs; H | 1981 |
Incidence of intolerance to food additives.
Topics: Angioedema; Aspirin; Asthma; Azo Compounds; Benzoates; Dermatitis, Contact; Food Additives; Food Hyp | 1980 |
Immunotherapy in children: past, present, and future. (Part II).
Topics: Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Humans; Hymenoptera; Immune Toleran | 1981 |
[Role of prostaglandins F and E in regulation of bronchial activity].
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Cyclooxygenase Inhibitors; Exerci | 1995 |
Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 1995 |
Efficacy and tolerability of nimesulide in asthmatic patients intolerant to aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Clinical Trials as Topic; Contraindication | 1993 |
Aspirin-induced early and late asthmatic response.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchoconstric | 1995 |
Clinical and experimental studies of leukotrienes as mediators of airway obstruction in humans.
Topics: Allergens; Aspirin; Asthma; Humans; Leukotriene Antagonists; Leukotrienes; Lung Diseases, Obstructiv | 1994 |
Aspirin-induced asthma: an update and novel findings.
Topics: Aspirin; Asthma; Humans; Infant; Leukotrienes; Prostaglandin-Endoperoxide Synthases; Respiratory Sys | 1994 |
Summary: leukotrienes as mediators of asthma in humans but not always in experimental animals.
Topics: Animals; Aspirin; Asthma; Disease Models, Animal; Humans; Leukotrienes; Species Specificity | 1994 |
Evidence for a specific role of leukotriene E4 in asthma and airway hyperresponsiveness.
Topics: Animals; Aspirin; Asthma; Constriction, Pathologic; Humans; Leukotriene E4; Leukotrienes; Respirator | 1994 |
[Therapeutic strategy in asthma: special cases and pseudo-asthma].
Topics: Adrenergic beta-Antagonists; Aspirin; Asthma; Asthma, Exercise-Induced; Cardiovascular System; Femal | 1995 |
[The classification of nonallergic eosinophilic rhinitis and sinus].
Topics: Age Factors; Aspirin; Asthma; Drug Tolerance; Eosinophils; Humans; Nasal Polyps; Neutrophils; Rhinit | 1994 |
[Aspirin-induced asthma].
Topics: Aspirin; Asthma; Humans | 1994 |
Leukotrienes as mediators of airway obstruction and inflammation in asthma.
Topics: Airway Obstruction; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid | 1995 |
Leukotriene inhibitors and antagonists in asthma.
Topics: Aspirin; Asthma; Humans; Leukotriene Antagonists; Leukotrienes | 1995 |
[Aspirin-induced asthma].
Topics: Adjuvants, Pharmaceutic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 1996 |
Nimesulide in the treatment of patients intolerant of aspirin and other NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Rhinitis; Sulfonamides | 1996 |
Mast cell effector mechanisms.
Topics: Animals; Aspirin; Asthma; Asthma, Exercise-Induced; Humans; Mast Cells | 1996 |
New insights into the understanding of asthma.
Topics: Air Pollutants; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Chronic Disease; | 1997 |
Mechanism of aspirin-induced asthma.
Topics: Animals; Aspirin; Asthma; Humans | 1997 |
[Aspirin-induced asthma (its clinical picture, pathogenesis and treatment)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Combined Moda | 1997 |
[Reevaluation of the roles of leukotrienes in allergic diseases].
Topics: Animals; Aspirin; Asthma; Humans; Leukotrienes; Rhinitis, Allergic, Perennial | 1998 |
[Asthma and aspirin].
Topics: Anti-Asthmatic Agents; Arachidonic Acids; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersens | 1998 |
A risk-benefit assessment of antileukotrienes in asthma.
Topics: Anti-Asthmatic Agents; Aspirin; Asthma; Bronchodilator Agents; Cold Temperature; Drug Interactions; | 1998 |
Hypothesis: decreased use of pediatric aspirin has contributed to the increasing prevalence of childhood asthma.
Topics: Animals; Aspirin; Asthma; Child; Child, Preschool; Humans; Prevalence; United States | 1998 |
Biosynthesis of cysteinyl-leucotrienes in aspirin-intolerant asthma.
Topics: Aspirin; Asthma; Cysteine; Glutathione Transferase; Humans; Leukotrienes; Lung; Polymorphism, Geneti | 1999 |
Leukotrienes, leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthma: an update. Part II: clinical studies with leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthma.
Topics: Anti-Asthmatic Agents; Aspirin; Asthma; Clinical Trials as Topic; Exercise; Glucocorticoids; Histami | 1999 |
Aspirin-induced asthma: advances in pathogenesis and management.
Topics: Aspirin; Asthma; Humans | 1999 |
Current synthetic notions on aspirin induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Drug Hypersensitivity; D | 1999 |
[Clinical diagnosis of bronchial asthma].
Topics: Aspergillosis, Allergic Bronchopulmonary; Aspirin; Asthma; Churg-Strauss Syndrome; Diagnosis, Differ | 1999 |
Measurement of leukotrienes in humans.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Body Fluids; Bronchitis; Bronchoconstricti | 2000 |
Treatment of aspirin-intolerant asthma with antileukotrienes.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchoconstriction | 2000 |
Genetic mechanisms in aspirin-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Eosinophilia; Female; Hum | 2000 |
[Aspirin: allergy or intolerance].
Topics: Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dru | 2000 |
[Asthma and aspirin intolerance].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Prevalence | 2000 |
Clinical features and diagnosis of aspirin induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Humans | 2000 |
Genetics of aspirin induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Eosinophilia; G | 2000 |
The importance of COX-2 inhibition for aspirin induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2000 |
Aspirin and asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Asthma; Bronchial Hyperreactivi | 2000 |
[A clinical case of 13 years old boy of aspirin-induced asthma with food allergy].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Male; Milk Hypersensit | 2000 |
[Aspirin-induced asthma and nose diseases].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Female; Humans; Male; Na | 2000 |
COX-1 sparing drugs in aspirin-sensitive asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2001 |
[Aspirin-induced asthma].
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase I | 2000 |
Recommending analgesics for people with asthma.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans | 2000 |
Aspirin-induced asthma.
Topics: Adult; Age Factors; Aspirin; Asthma; Female; Humans; Leukotrienes; Male; Sex Factors | 2001 |
Report of the INTERASMA Working Group on Standardization of Inhalation Provocation Tests in Aspirin-induced Asthma. Oral and inhalation provocation tests for the diagnosis of aspirin-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Humans | 2001 |
[Aspirin-induced asthma].
Topics: Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Huma | 2001 |
The use of analgesics in patients with asthma.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2001 |
The mechanisms of aspirin-intolerant asthma and its management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensi | 2002 |
A new insight into aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Eosinophils; European Union; Glutat | 2002 |
Aspirin-induced rhinitis and asthma.
Topics: Aspirin; Asthma; Eicosanoids; Glutathione Transferase; Humans; Rhinitis; Sinusitis | 2001 |
[Asthma with aspirin intolerance].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersen | 2002 |
Testing for aspirin hypersensitivity.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocati | 2002 |
Effective use of analgesic drugs.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1976 |
Aspirin intolerance--a review.
Topics: Adolescent; Adult; Age Factors; Aged; Angioedema; Aspirin; Asthma; Blood Coagulation; Child; Child, | 1977 |
[Prostoglandins and thromboxans in the regulation of bronchial function].
Topics: Animals; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Fatty Acids, Unsaturated; Humans; Hydroxy | 1977 |
[Asthma and aspirin intolerance].
Topics: Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Metabolism, Inborn Errors; Nasal Po | 1978 |
[Drug-induced asthma with special reference to the so-called aspirin-induced asthma (author's transl)].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1978 |
[Clinical pharmacology of acetylsalicylic acid].
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Asthma; Female; Humans; Hydrolysis; Intestinal Absorp | 1979 |
[Acetylsalicyl acid (ASA) and prostaglandins].
Topics: Arthritis, Rheumatoid; Aspirin; Asthma; Chemical Phenomena; Chemistry; Collagen; Drug Interactions; | 1977 |
Modern aspects in diagnosis and treatment of the asthmatic patient.
Topics: Adrenal Cortex Hormones; Adult; Affective Symptoms; Anti-Bacterial Agents; Aspirin; Asthma; Bronchi; | 1976 |
[Polyposis of the nasal sinuses. Epidemiology and clinical aspects of 350 cases. Treatment and results with a follow-up over 5 years on 93 cases].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Drug Hypersensitivity; Ethmoid S | 1992 |
The pathobiology of bronchial asthma.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basement | 1992 |
Nasal polyps, bronchial asthma and aspirin sensitivity.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Rhinitis; Syndrome | 1992 |
Aspirin sensitive asthma.
Topics: Animals; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Humans; Leukocyt | 1992 |
Asthma-producing drugs.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1992 |
Precipitating factors of asthma.
Topics: Air Pollution; Allergens; Aspirin; Asthma; Asthma, Exercise-Induced; Child; Humans; Virus Diseases | 1992 |
Mechanism of aspirin sensitivity.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Leukotrienes | 1992 |
The role of atopy in asthma.
Topics: Age Factors; Allergens; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate | 1991 |
[Nasosinusal polyposis. Indications. Results. Apropos of 222 ethmoidectomies].
Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Ethmoid Sinus; Female; Humans; Male; Middle Age | 1991 |
Sulphidopeptide leukotrienes in asthma.
Topics: Animals; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstric | 1991 |
The cyclooxygenase theory of aspirin-induced asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Dr | 1990 |
The mast cell as a primary effector cell in the pathogenesis of asthma.
Topics: Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Eosinophils; Histamine Release; Humans; Immun | 1986 |
Desensitization to aspirin in aspirin-sensitive patients with rhino-sinusitis and asthma: a review.
Topics: Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Nasal Polyps; Rhinitis | 1989 |
Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma.
Topics: Acetaminophen; Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Double-Blind Method; Drug | 1989 |
Eicosanoids in aspirin-induced asthma.
Topics: Animals; Aspirin; Asthma; Eicosanoids; Humans | 1989 |
Origin of aspirin-induced asthma.
Topics: Animals; Aspirin; Asthma; Humans | 1989 |
[Asthma relieved by aspirin].
Topics: Arachidonic Acids; Aspirin; Asthma; Bronchial Provocation Tests; Female; Humans; Male; Middle Aged | 1989 |
Aspirin-induced asthma: new insights into pathogenesis and clinical presentation of drug intolerance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Glucocorticoids; Humans; Leukotrienes | 1989 |
[Hypersensitivity to aspirin and other non-steroidal anti- inflammatory agents--the methods of detecting the hypersensitivity and the development of the state of tolerance].
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet | 1989 |
[Anesthesia of a patient with the Fernand-Widal syndrome].
Topics: Anesthesia; Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Syndrome | 1989 |
The role of eicosanoids in respiratory mucus hypersecretion.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Bronchial Diseases; Cells, Cultured; Fatty Acids, Unsat | 1985 |
[The problem of aspirin-induced asthma].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Desensitization, Immunologic | 1988 |
Aspirin sensitivity and allergy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Drug Interactions; | 1988 |
Bronchial asthma, nasal polyps, and aspirin sensitivity: Samter's syndrome.
Topics: Aspirin; Asthma; Humans; Nasal Polyps; Syndrome | 1988 |
Allergic and pseudoallergic reactions to non-narcotic analgesics.
Topics: Analgesics; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Drug Hypersensitivity; Humans; Pro | 1986 |
[Asthma and platelets].
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Drug Tolerance; Humans; Plate | 1988 |
[Acetylsalicylic acid pseudoallergy: an anomaly of thrombocyte function?].
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Humans | 1988 |
[Adverse reactions to aspirin in bronchial asthma].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1987 |
The role of the eosinophil in the pathogenesis of asthma.
Topics: Adrenal Cortex Hormones; Antigens, Surface; Aspirin; Asthma; Blood Proteins; Bronchi; Chemotactic Fa | 1987 |
Adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs.
Topics: Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensiti | 1987 |
[Aspirin-induced asthma].
Topics: Aspirin; Asthma; Humans | 1986 |
Monosodium glutamate-induced asthma: study of the potential risk of 30 asthmatics and review of the literature.
Topics: Adolescent; Adult; Allergens; Aspirin; Asthma; Ethanol; Female; Food Additives; Glutamates; Humans; | 1987 |
[Asthma, aspirin, prostaglandins and leukotrienes].
Topics: Arachidonic Acids; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Pro | 1986 |
[Development of aspirin tolerance in hypersensitive persons. II. Clinical usefulness and the mechanisms of the phenomenon of aspirin tolerance].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Drug Tolerance; Humans; Rhinitis, Allergic, Perennial; Tachy | 1986 |
Analgesics, allergy and asthma.
Topics: Analgesics; Anaphylaxis; Aspirin; Asthma; Drug Hypersensitivity; Humans | 1986 |
Precipitating factors in asthma. Aspirin, sulfites, and other drugs and chemicals.
Topics: Adult; Aspirin; Asthma; Child; Food Additives; Food Preservation; Humans; Sulfites; Sulfur Dioxide; | 1985 |
Bronchial response to nonsteroidal anti-inflammatory drugs in asthmatic patients.
Topics: Adult; Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Bronchi; Bronchial Provocation | 1985 |
Continuing medical education. Asthma in infants and children: Part 1.
Topics: Airway Resistance; Allergens; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Child, Pres | 1985 |
Clinical spectrum of adverse reactions to tartrazine.
Topics: Angioedema; Aspirin; Asthma; Azo Compounds; Child; Child, Preschool; Dermatitis, Contact; Diet; Food | 1985 |
Aspirin-sensitive asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensit | 1985 |
Asthma: recent developments in treatment.
Topics: Acute Disease; Aminophylline; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Bude | 1985 |
[The pathogenic mechanisms and treatment of asthma].
Topics: Adult; Aged; Allergens; Aspirin; Asthma; Child; Desensitization, Immunologic; Female; Glucocorticoid | 1974 |
Prostaglandins and asthma.
Topics: Aerosols; Airway Resistance; Animals; Aspirin; Asthma; Atropine; Bronchi; Bronchial Spasm; Cyclic AM | 1973 |
The prostaglandins: their significance in clinical practice.
Topics: Abortion, Induced; Anemia, Hemolytic; Animals; Aspirin; Asthma; Chemical Phenomena; Chemistry; Cycli | 1974 |
Endogenous broncho-active substances and their antagonism.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Asthma; Bradykinin; Bronchi; Drug Antagonis | 1970 |
The pathogenesis of asthma.
Topics: Acetaminophen; Adult; Affective Symptoms; Air Pollution; Aspirin; Asthma; Autonomic Nervous System; | 1974 |
[Bronchial asthma caused by dyes].
Topics: Aspirin; Asthma; Azo Compounds; Coloring Agents; Conjunctivitis; Drug Hypersensitivity; Food Additiv | 1973 |
[What is known today about the immunology and biochemistry of asthma? Immunologic reaction in asthma].
Topics: Adenylyl Cyclases; Allergens; Aspirin; Asthma; Bronchi; Desensitization, Immunologic; Drug Hypersens | 1974 |
[Allergic reactions in asthmatics caused by salicylates and food additives].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Food Additives; Food Preservatives; Humans; Salicylates | 1974 |
[Bronchial asthma. A review for postgraduate medical education].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Child; Chronic Disease; Czechoslovakia; Diagnosis, Differe | 1971 |
Cardiac manifestations due to hypersensitivity.
Topics: Adams-Stokes Syndrome; Anaphylaxis; Angina Pectoris; Antigen-Antibody Complex; Arrhythmias, Cardiac; | 1970 |
134 trials available for aspirin and Asthma, Bronchial
| Article | Year |
|---|---|
Nonsteroidal Anti-inflammatory Drug (NSAID) Tolerance After Biological Therapy in Patients With NSAID-Exacerbated Respiratory Disease: A Randomized Comparative Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biological Therapy; Humans; Inflammation; | 2023 |
Leukotriene E
Topics: Acetates; Adult; Aspirin; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Cross-Over Studies | 2018 |
Effects of Reslizumab on Asthma Outcomes in a Subgroup of Eosinophilic Asthma Patients with Self-Reported Chronic Rhinosinusitis with Nasal Polyps.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2019 |
Effects of Reslizumab on Asthma Outcomes in a Subgroup of Eosinophilic Asthma Patients with Self-Reported Chronic Rhinosinusitis with Nasal Polyps.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2019 |
Effects of Reslizumab on Asthma Outcomes in a Subgroup of Eosinophilic Asthma Patients with Self-Reported Chronic Rhinosinusitis with Nasal Polyps.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2019 |
Effects of Reslizumab on Asthma Outcomes in a Subgroup of Eosinophilic Asthma Patients with Self-Reported Chronic Rhinosinusitis with Nasal Polyps.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2019 |
Effects of omalizumab on eosinophil cationic peptide, 25-hydroxyvitamin-D, IL-1β and sCD200 in cases of Samter's syndrome: 36 months follow-up.
Topics: Adult; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Antigens | 2013 |
Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study.
Topics: Administration, Oral; Adult; Aged; Allergens; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Dise | 2014 |
Treatment of aspirin exacerbated respiratory disease with a low salicylate diet: a pilot crossover study.
Topics: Adult; Aged; Aspirin; Asthma; Cross-Over Studies; Desensitization, Immunologic; Drug Hypersensitivit | 2015 |
Aspirin does not preferentially potentiate IgE-dependent basophil CD63 upregulation in patients with food-dependent exercise-induced anaphylaxis.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophils; Drug Hypers | 2015 |
Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, | 2008 |
Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, | 2008 |
Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, | 2008 |
Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, | 2008 |
The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Chronic Disease; | 2010 |
Asthma, chronic obstructive pulmonary disease, and type 2 diabetes in the Women's Health Study.
Topics: Aspirin; Asthma; Bronchitis, Chronic; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Hu | 2010 |
Topical gel therapy for sinonasal polyposis in Samter's triad: preliminary report.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Asth | 2012 |
The safety of celecoxib in patients with aspirin-sensitive asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase Inhibitors; Dose | 2002 |
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis.
Topics: Adult; Aged; Aspirin; Asthma; Biopsy; Desensitization, Immunologic; Down-Regulation; Drug Hypersensi | 2002 |
Clinical and genetic features underlying the response of patients with bronchial asthma to treatment with a leukotriene receptor antagonist.
Topics: Acetates; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyc | 2002 |
Early effects of aspirin desensitization treatment in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Aged; Aspirin; Asthma; Female; Glucocorticoids; Humans; Male; Middle Aged; Prednisone; Respir | 2003 |
Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cross-Over Studies | 2003 |
[The effectiveness of leukotriene antagonists in the treatment of aspirin-intolerant asthmatic patients].
Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleeding Time; Cyclopropa | 2003 |
Nasal versus bronchial and nasal response to oral aspirin challenge: Clinical and biochemical differences between patients with aspirin-induced asthma/rhinitis.
Topics: Administration, Oral; Adult; Aspirin; Asthma; Bronchi; Dinoprost; Female; Humans; Leukotriene E4; Ma | 2003 |
Montelukast 10 mg improves nasal function and nasal response to aspirin in ASA-sensitive asthmatics: a controlled study vs placebo.
Topics: Acetates; Adult; Airway Resistance; Aspirin; Asthma; Cyclopropanes; Double-Blind Method; Female; Hum | 2004 |
Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase In | 2004 |
Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma.
Topics: Adult; Alleles; Aspirin; Asthma; Dinoprost; Drug Hypersensitivity; Eicosanoids; Female; Genotype; Gl | 2004 |
Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients.
Topics: Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celec | 2004 |
Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Topics: Acetates; Administration, Inhalation; Adult; Aspirin; Asthma; Confidence Intervals; Cross-Over Studi | 2004 |
Safety of high-dose rofecoxib in patients with aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cyclooxygenase Inhibitors | 2004 |
Tacrolimus reduces urinary excretion of leukotriene E(4) and inhibits aspirin-induced asthma to threshold dose of aspirin.
Topics: Adult; Aspirin; Asthma; ATP Binding Cassette Transporter, Subfamily B; Bronchoconstriction; Cross-Ov | 2004 |
Failure of tacrolimus to prevent aspirin-induced respiratory reactions in patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensi | 2005 |
The use of etoricoxib in patients with bronchial asthma associated with aspirin sensitivity.
Topics: Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Etoricoxib; Humans; Pyridines; Su | 2006 |
Nasal and bronchial tolerability of Rofecoxib in patients with aspirin induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchoconstriction; Cyclooxygenase 2 Inhibitors; Female; Forced Expiratory | 2006 |
[Nasal provocation test with lysine-aspirin in diagnosis of nonallergic rhinitis with eosinophilia].
Topics: Administration, Intranasal; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; D | 2006 |
Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provoca | 2006 |
Safety of meloxicam in aspirin-hypersensitive patients with asthma and/or nasal polyps. A challenge-proven study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibito | 2007 |
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges.
Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; | 2006 |
Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control | 2008 |
Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma.
Topics: Administration, Intranasal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Endosco | 2007 |
Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dose-Re | 2008 |
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Bronchial Provocation | 2008 |
Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study.
Topics: Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Asthma; | 2008 |
Failure of children with asthma to respond to daily aspirin therapy.
Topics: Adolescent; Aspirin; Asthma; Child; Clinical Trials as Topic; Dinoprost; Dinoprostone; Double-Blind | 1983 |
Asthma improved by aspirin-like drugs.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Double-Blind Method; Fem | 1983 |
Aspirin-sensitive rhinosinusitis asthma: a double-blind crossover study of treatment with aspirin.
Topics: Aspirin; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Hypersensitivity; Forced Expira | 1984 |
The effect of ketotifen on aspirin-induced asthmatic reactions.
Topics: Adult; Aged; Aspirin; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Drug H | 1983 |
Asthma relieved by acetylsalicylic acid and nonsteroid anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Dipyrone; Female; Forced Expiratory Volume; Humans; Indom | 1984 |
Oral and inhaled sodium cromoglycate in challenge test with food allergens or acetylsalicylic acid.
Topics: Administration, Oral; Adult; Aerosols; Aspirin; Asthma; Bronchial Provocation Tests; Cromolyn Sodium | 1981 |
Adverse pulmonary responses to aspirin and acetaminophen in chronic childhood asthma.
Topics: Acetaminophen; Adolescent; Aspirin; Asthma; Child; Double-Blind Method; Female; Forced Expiratory Vo | 1983 |
[Guacetisal in the treatment of acute and chronic bronchopneumopathy].
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Aspirin; Asthma; Bronchitis; Bronchodilator Agents; Bron | 1981 |
[Guacetisal: a new molecule with balsamic-antiphlogistic action. Clinical study].
Topics: Adult; Aged; Aspirin; Asthma; Bronchitis; Bronchopneumonia; Clinical Trials as Topic; Female; Humans | 1981 |
[Clinical trials of a new preparation in chronic bronchopneumopathies].
Topics: Adult; Aged; Aspirin; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Cough; Female; | 1981 |
Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects.
Topics: Acetaminophen; Adult; Aged; Aspirin; Asthma; Cross Reactions; Dose-Response Relationship, Immunologi | 1995 |
Hydrocortisone sodium succinate does not cross-react with aspirin in aspirin-sensitive patients with asthma.
Topics: Adult; Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Double-Blind Method; Drug Hyp | 1995 |
A comparison of intravenous and inhalational maintenance anaesthesia for endoscopic procedures in the aspirin intolerance syndrome.
Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, I | 1995 |
Inhaled lysine acetylsalicylate (L-ASA) attenuates the bronchoconstrictor response to adenosine 5'-monophosphate (AMP) in asthmatic subjects.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Analysis of Variance; Anti-Inflammatory | 1995 |
Steroid-sparing effect of inhaled lysine acetylsalicylate and furosemide in high-dose beclomethasone-dependent asthma.
Topics: Administration, Inhalation; Adolescent; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asth | 1995 |
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma.
Topics: Adult; Aspirin; Asthma; Blood Proteins; Chymases; Cross-Over Studies; Double-Blind Method; Eosinophi | 1994 |
Time-limited protective effect of inhaled frusemide against aspirin-induced bronchoconstriction in aspirin-sensitive asthmatics.
Topics: Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Bronchoconstriction; Double-Blind Method; | 1994 |
[A comparative evaluation of the therapeutic action of different methods of intermittent plasmapheresis in bronchial asthma].
Topics: Adult; Aged; Antigen-Antibody Complex; Aspirin; Asthma; Female; Humans; Hypersensitivity, Immediate; | 1994 |
Oral challenges to detect aspirin and sulfite sensitivity in asthma.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cro | 1994 |
Inhibition of analgesic-induced asthma by leukotriene receptor antagonist ONO-1078.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chromones; Dipyrone; | 1994 |
Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Calcimycin; Double-Blind Method; Female; Forced | 1994 |
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1993 |
Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA.
Topics: Adult; Aspirin; Asthma; Body Fluids; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; | 1993 |
Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Dru | 1994 |
[Amlexanox has an acute bronchodilator effect in patients with aspirin-induced asthma (AIA)].
Topics: Adult; Aged; Aminopyridines; Aspirin; Asthma; Bronchi; Bronchoconstriction; Bronchodilator Agents; D | 1993 |
The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin.
Topics: Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Bronchoconstriction; Double-Blind Method; Drug | 1993 |
Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects.
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Bronchi; Double-Blind Method; Female; Forced Expiratory | 1993 |
The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics.
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchodilator Agents; Female; Hu | 1993 |
Protective and bronchodilator effects of prostaglandin E and salbutamol in aspirin-induced asthma.
Topics: Administration, Inhalation; Administration, Oral; Adult; Albuterol; Alprostadil; Aspirin; Asthma; Br | 1996 |
Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Broncho | 1996 |
Antipyretic effect of Lumbricus spencer in acetylsalicylic acid-induced asthma.
Topics: Adult; Analgesics, Non-Narcotic; Anti-Asthmatic Agents; Aspirin; Asthma; Body Temperature; Female; H | 1996 |
Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction.
Topics: Adult; Airway Obstruction; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Chromatography, | 1996 |
Inhaled lysine acetylsalicylate (L-ASA) attenuates histamine-induced bronchoconstriction in asthma.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchoconstriction; Cyclooxygenase Inhibitors; | 1996 |
Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; | 1996 |
Changes in neurokinin A airway responsiveness with inhaled lysine-acetylsalicylate in asthma.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Constriction, Patho | 1996 |
Attenuation of aspirin-induced bronchoconstriction by sodium cromoglycate and nedocromil sodium.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocati | 1997 |
Activity of inhaled lysine acetylsalicylate (L-ASA) on bradykinin-induced bronchoconstriction in asthmatics: evidence of contribution of prostaglandins.
Topics: Administration, Inhalation; Adult; Airway Resistance; Analysis of Variance; Aspirin; Asthma; Bradyki | 1997 |
Protective effect of inhaled lysine acetylsalicylate on allergen-induced early and late asthmatic reactions.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; A | 1997 |
Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma.
Topics: Administration, Intranasal; Adult; Androstadienes; Anti-Allergic Agents; Aspirin; Asthma; Chronic Di | 1997 |
Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthma.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 1998 |
Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
Topics: Aspirin; Asthma; Blood Platelets; Cross-Over Studies; Double-Blind Method; Enzyme-Linked Immunosorbe | 1997 |
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics.
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperr | 1998 |
[A complex evaluation of the efficacy of aldecin in treating bronchial asthma patients].
Topics: Administration, Inhalation; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroi | 1998 |
Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Aspirin; Asthma; Bronchial P | 1998 |
Bronchial hyperresponsiveness, hypersensitivity to analgesics and urinary leukotriene E4 excretion in patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Test | 1998 |
Effect of acyclovir on bronchoconstriction and urinary leukotriene E4 excretion in aspirin-induced asthma.
Topics: Acyclovir; Administration, Oral; Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchoconstriction; | 1998 |
Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; A | 1999 |
Dynamics of eicosanoids in peripheral blood cells during bronchial provocation in aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cells, Cultured; | 1999 |
Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; Bronchial Hyperreac | 1999 |
A six week double blind, placebo controlled, crossover study of the effect of misoprostol in the treatment of aspirin sensitive asthma.
Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross- | 1999 |
Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bradykinin; Bronchial Provocation Tests; Broncho | 1999 |
Efficacy of leukotriene receptor antagonist in bronchial hyperresponsiveness and hypersensitivity to analgesic in aspirin-intolerant asthma.
Topics: Adult; Analgesics; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; | 2000 |
The use of nimesulide in patients with acetylsalicylic acid and nonsteroidal anti-inflammatory drug intolerance.
Topics: Administration, Oral; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1999 |
Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; | 2000 |
Safety of a specific COX-2 inhibitor in aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross-Over Studies; Cyclooxygenase | 2001 |
Lack of cross-reactivity between rofecoxib and aspirin in aspirin-sensitive patients with asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cyclooxygenase Inhibitors | 2001 |
Cromolyn sodium suppresses eosinophilic inflammation in patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Protei | 2001 |
[Epifamine efficacy in aspirin bronchial asthma].
Topics: Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Epiphyses; F | 2001 |
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial.
Topics: Acetates; Administration, Oral; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; | 2002 |
Nasal provocation test (NPT) with aspirin: a sensitive and safe method to diagnose aspirin-induced asthma (AIA).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; M | 2002 |
Letter: Aspirin in exercise-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchi; Clinical Trials as Topic; Humans; Physical Exertion; Placebos; Pros | 1975 |
Analgesic sensitivity in children with asthma.
Topics: Acetaminophen; Adolescent; Airway Obstruction; Analgesics; Aspirin; Asthma; Child; Clinical Trials a | 1978 |
Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics.
Topics: Adult; Aged; alpha 1-Antitrypsin; Aspirin; Asthma; Benzoates; Bronchial Spasm; Complement C1 Inactiv | 1979 |
Aspirin and tartrazine oral challenge: incidence of adverse response in chronic childhood asthma.
Topics: Adolescent; Aspirin; Asthma; Azo Compounds; Blood Pressure; Child; Chronic Disease; Clinical Trials | 1977 |
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forc | 1978 |
[Pharmacotherapy of asthma and its prospects].
Topics: Aspirin; Asthma; Beclomethasone; Clinical Trials as Topic; Humans; Sympathomimetics | 1979 |
Cromolyn sodium in the treatment of asthma associated with aspirin hypersensitivity and nasal polyps.
Topics: Adult; Aspirin; Asthma; Child; Cromolyn Sodium; Drug Hypersensitivity; Forced Expiratory Flow Rates; | 1977 |
Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics.
Topics: Adolescent; Adult; Aspirin; Asthma; Azo Compounds; Benzoates; Bronchial Spasm; Coloring Agents; Doub | 1979 |
[No objections against solosine in acetylsalicylic acid sensitive asthma patients].
Topics: Aspirin; Asthma; Humans; Salicylamides | 1979 |
Tolerance of guaiacolic ester of acetylsalicylic acid by patients with aspirin-asthma.
Topics: Airway Resistance; Aspirin; Asthma; Drug Tolerance; Female; Humans; Male; Middle Aged; Placebos; Ple | 1979 |
Refractory period to aspirin in a patient with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Humans; Male; Mi | 1976 |
Response of patients with asthma and aspirin idiosyncrasy to tartrazine (a dye commonly used in the food and drug industries).
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Clinical Trials as Topic; Female; Humans; Male; Middle Age | 1976 |
Aspirin intolerance in chronic childhood asthma: Detected by oral challenge.
Topics: Adolescent; Aspirin; Asthma; California; Child; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1975 |
Aspirin and exercise-induced asthma.
Topics: Adult; Airway Resistance; Aspirin; Asthma; Forced Expiratory Volume; Humans; Maximal Expiratory Flow | 1976 |
Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma.
Topics: Adolescent; Adult; Aged; Aging; Airway Obstruction; Aspirin; Asthma; Azo Compounds; Benzenesulfonate | 1976 |
Precipitation of asthma attacks in Melanesian adults by sodium metabisulphite.
Topics: Adult; Areca; Aspirin; Asthma; Bronchial Provocation Tests; Double-Blind Method; Ethnicity; Female; | 1992 |
Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients.
Topics: Administration, Intranasal; Adult; Albumins; Aspirin; Asthma; Dinoprost; Dinoprostone; Drug Hypersen | 1992 |
Urinary leukotriene E4 after lysine-aspirin inhalation in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction | 1992 |
[Sodium cromoglycate nebulized solution has an acute bronchodilative effect in patients with aspirin-intolerant asthma (AIA)].
Topics: Administration, Inhalation; Aspirin; Asthma; Bronchodilator Agents; Cromolyn Sodium; Double-Blind Me | 1992 |
Effect of inhaled furosemide on the bronchial response to lysine-aspirin inhalation in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction | 1992 |
Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; F | 1991 |
The potent and selective sulfidopeptide leukotriene antagonist, SK&F 104353, inhibits aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Dicarboxylic Acids; Drug Evaluation; Female; Forced Expiratory Volume; Human | 1991 |
Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Choline; Double-Bl | 1990 |
Choline magnesium trisalicylate in patients with aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Choline; Double-Blind Method; Drug | 1990 |
Oral gold therapy in steroid-dependent asthma, nasal polyposis, and aspirin hypersensitivity.
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Auranofin; Drug Hypersensitivity; Humans; Nasal Polyps; Pr | 1990 |
Salsalate cross-sensitivity in aspirin-sensitive patients with asthma.
Topics: Acetaminophen; Administration, Oral; Aspirin; Asthma; Double-Blind Method; Drug Hypersensitivity; Fo | 1990 |
Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine.
Topics: Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Cli | 1989 |
Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma.
Topics: Acetaminophen; Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Double-Blind Method; Drug | 1989 |
[Asthma improved by acetylsalicylic acid].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provoca | 1987 |
The effect of prostacyclin on asthma precipitated by aspirin.
Topics: Adult; Aspirin; Asthma; Bronchi; Clinical Trials as Topic; Double-Blind Method; Drug Hypersensitivit | 1987 |
Intolerance to tartrazine in aspirin-induced asthma: results of a multicenter study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aspirin; Asthma; Azo Compounds; Dose-Response Relatio | 1988 |
Bleeding time and PAF-acether-induced platelet aggregation in atopy.
Topics: Adult; Aspirin; Asthma; Bleeding Time; Female; Humans; Male; Middle Aged; Platelet Activating Factor | 1987 |
Lack of effect of i.v. prostacyclin on aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Clinical Trials as Topic; Double-Blind Method; Epoprostenol; Female; Humans; | 1986 |
Tolerance of carprofen in patients with asthma caused by non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Asthma; Carbazoles; Drug Evaluation; Drug Hypersensi | 1985 |
Hydrocortisone and airflow impairment in aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans | 1985 |
Detection of aspirin sensitivity by pulmonary function tests.
Topics: Aspirin; Asthma; Clinical Trials as Topic; Drug Hypersensitivity; Evaluation Studies as Topic; Human | 1973 |
[Urticaria provoked by preservatives and coloring agents in food and drugs].
Topics: Angioedema; Aspirin; Asthma; Azo Compounds; Benzoates; Chemical Phenomena; Chemistry; Food Additives | 1973 |
858 other studies available for aspirin and Asthma, Bronchial
| Article | Year |
|---|---|
10H-Phenothiazines: a new class of enzyme inhibitors for inflammatory diseases.
Topics: Anti-Inflammatory Agents; Asthma; Autoimmune Diseases; Enzyme Inhibitors; Humans; Inflammation; Phen | 2009 |
Inheritance of NSAID-Exacerbated Respiratory Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Humans; Nasal Pol | 2023 |
Aspirin desensitization following endoscopic sinus surgery is effective in patients with nonsteroidal antiinflammatory drug exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Di | 2023 |
What happens to basophils and tryptase, LXA
Topics: Aspirin; Asthma; Basophils; Desensitization, Immunologic; Humans; Tryptases | 2023 |
What happens to basophils and tryptase, LXA
Topics: Aspirin; Asthma; Basophils; Desensitization, Immunologic; Humans; Tryptases | 2023 |
What happens to basophils and tryptase, LXA
Topics: Aspirin; Asthma; Basophils; Desensitization, Immunologic; Humans; Tryptases | 2023 |
What happens to basophils and tryptase, LXA
Topics: Aspirin; Asthma; Basophils; Desensitization, Immunologic; Humans; Tryptases | 2023 |
Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Humans; Nasal Poly | 2023 |
Comparison of 300 mg versus 600 mg daily maintenance doses of aspirin treatment after desensitization in N-ERD: A three-year multicentre experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Nasal Polyps; Retrospective Studie | 2023 |
Mechanistic and clinical updates in AERD: 2021-2022.
Topics: Adult; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Disease; Humans; Nasal Polyps; Rhinitis | 2023 |
Comparison of the clinical outcomes of patients with NSAID-exacerbated respiratory disease receiving aspirin or biologicals.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biological Products; Female; Humans; Male; | 2023 |
Demographic and clinical profile of patients with chronic rhinosinusitis in Saudi Arabia.
Topics: Aspirin; Asthma; Chronic Disease; Cross-Sectional Studies; Female; Humans; Male; Nasal Polyps; Preva | 2023 |
Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Eosinophilia; Eosinophils; Humans; Sinusitis | 2023 |
Association Between Aspirin-Exacerbated Respiratory Disease and Atherosclerotic Cardiovascular Disease: A Retrospective Review of US Claims Data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Cardiovascular Di | 2023 |
Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease.
Topics: Animals; Aspirin; Asthma; Asthma, Aspirin-Induced; Diabetes Mellitus, Type 2; Glucagon-Like Peptide- | 2023 |
Perimenstrual Asthma in Aspirin-Exacerbated Respiratory Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Female; Humans; L | 2020 |
Clinical characteristics and aspirin desensitization in Thai patients with a suggestive history of NSAID-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Human | 2022 |
Analysis of the impact of bronchial asthma and hypersensitivity to aspirin on the clinical course of chronic sinusitis with nasal polyps.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Case-Control Studies; Drug Hypersensitivity; Fema | 2019 |
Eosinophilic Asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Child; Humans; Hypersensitivit | 2020 |
Clinical-Cytological-Grading and phenotyping in patients with chronic rhinosinusitis with nasal polyps: the relevance in clinical practice.
Topics: Adult; Aspirin; Asthma; Cell Biology; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; | 2020 |
Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Bronchoalveolar L | 2021 |
A multicenter approach to evaluate omalizumab effectiveness in Samter's triad.
Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma | 2020 |
Specialized Proresolving Mediators Overcome Immune Suppression Induced by Exposure to Secondhand Smoke.
Topics: Animals; Antibodies; Aspirin; Asthma; B-Lymphocytes; Bronchoalveolar Lavage Fluid; Cytokines; Docosa | 2020 |
Aspirin-Exacerbated Respiratory Disease: Association Between Patient-Reported Sinus and Asthma Morbidity.
Topics: Adult; Aspirin; Asthma; Chronic Disease; Female; Humans; Male; Middle Aged; Morbidity; Rhinitis | 2021 |
Atypical eosinophilic granulomatosis with polyangiitis with spontaneous aspirin reactivity and immunoglobulin E-mediated anaphylaxis.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; C-Reactive Protein; CD | 2021 |
Analysis of basophil activation in patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophils; Female; Humans; Ma | 2017 |
Prognostic value of nasal cytology and clinical factors in nasal polyps development in patients at risk: can the beginning predict the end?
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Eosinophilia; Female; Humans; Male; Middle Aged; Nasal Muc | 2017 |
Leukotrienes and sex: strange bedfellows?
Topics: Aspirin; Asthma; Eicosanoids; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Platelet | 2017 |
Acetylsalicylic Acid Produces Different Effects on the Production of Active Oxygen Species by Activated Platelets in Different Inflammatory Diseases.
Topics: Aspirin; Asthma; Blood Platelets; Case-Control Studies; Drug Evaluation, Preclinical; Humans; Laparo | 2017 |
[Is celecoxib a safe alternative for the Fernand Widal syndrome?]
Topics: Adult; Aged; Aspirin; Asthma; Case-Control Studies; Celecoxib; Drug Hypersensitivity; Female; France | 2018 |
Otitis media with effusion in aspirin-exacerbated respiratory disease patients-A series of 22 cases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Eosino | 2018 |
Factors associated with lung cancer in COPD patients.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Aged; Aspirin; Asthma; Comorbidity | 2018 |
Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study.
Topics: Administration, Inhalation; Aspirin; Asthma; Case-Control Studies; Chronic Disease; Cross-Sectional | 2018 |
Role of asthma and intolerance to acetylsalicylic acid on the redox profile in nasal polyp tissue.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Glutathione; Glutathione Tr | 2018 |
Asthma exacerbation by aspirin and chemical additives: use of a nucleotide template model to investigate potential mechanisms.
Topics: Aspirin; Asthma; Models, Molecular; Molecular Conformation; Nucleotides | 2018 |
Differences in urinary leukotriene E4 levels and distribution of eosinophils between chronic rhinosinusitis patients with aspirin-intolerant and-tolerant asthma.
Topics: Aspirin; Asthma; Chronic Disease; Drug Tolerance; Eosinophils; Humans; Leukotriene E4; Rhinitis; Sin | 2016 |
Richard Studley Farr, MD.
Topics: Allergy and Immunology; Aspirin; Asthma; Drug Hypersensitivity; History, 20th Century | 2018 |
NSAIDs-hypersensitivity often induces a blended reaction pattern involving multiple organs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Huma | 2018 |
Prostaglandin E
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarkers | 2019 |
Sputum biomarkers during aspirin desensitization in nonsteroidal anti-inflammatory drugs exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Carrier Proteins; | 2019 |
Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in a Kurd Population.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cytochrome P-450 CYP2C1 | 2020 |
The bacteriology of chronic rhinosinusitis and the pre-eminence of Staphylococcus aureus in revision patients.
Topics: Adult; Aged; Aspirin; Asthma; Chronic Disease; Female; Humans; Male; Middle Aged; Nasal Polyps; Pseu | 2013 |
Characteristics of perimenstrual asthma and its relation to asthma severity and control: data from the Severe Asthma Research Program.
Topics: Adolescent; Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Female; Humans; Menstruation; Middle Aged | 2013 |
Aspirin sensitivity does not compromise quality-of-life outcomes in patients with Samter's triad.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; | 2014 |
Samter's triad in childhood: a warning for those prescribing NSAIDs.
Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthm | 2013 |
Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Cysteine; Cytokines; Eosinophils; Female; Humans; Interfer | 2013 |
Major comorbid conditions in asthma and association with asthma-related hospitalizations and emergency department admissions in adults: results from the German National Health Telephone Interview Survey (GEDA) 2010.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Comorbidity; Cross-Sectional Studies; Emergency Service, H | 2013 |
Aspirin 300 mg/day is effective for treating aspirin-exacerbated respiratory disease.
Topics: Adult; Aspirin; Asthma; Asthma, Aspirin-Induced; Female; Follow-Up Studies; Humans; Male; Middle Age | 2013 |
Plasma apolipoprotein H levels are different between aspirin induced respiratory diseases and aspirin tolerant asthma.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Asthma, Aspirin-Induced; beta 2-Glycoprotein I; Bio | 2014 |
Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Drug Resistance; Eosinophils; Fe | 2013 |
Concurrent coxibs and anti-platelet therapy unmasks aspirin-exacerbated respiratory disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2 Inhibitors; Dyslipi | 2013 |
Association analysis of member RAS oncogene family gene polymorphisms with aspirin intolerance in asthmatic patients.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Base Sequence; DNA Primers; Drug Tolerance; Female; Gene F | 2014 |
Samter's triad with aural involvement: a novel approach to management.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Drug Hypersensitiv | 2014 |
Aspirin exacerbated respiratory disease: the search for a biomarker.
Topics: Aspirin; Asthma; Biomarkers; Cell Adhesion Molecules; Humans | 2014 |
Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
Topics: Adult; Aged; Aspirin; Asthma; Calcium; Cell Movement; Dinoprostone; Eosinophils; Female; Humans; Lip | 2014 |
Phenotype of asthma related with high serum periostin levels.
Topics: Adult; Asian People; Aspirin; Asthma; Cell Adhesion Molecules; Cytokines; Drug Tolerance; Eosinophil | 2015 |
[Aspirin hypersensitivity: characteristics and diagnostic approach].
Topics: Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Blood Cell Count; Blood Platelets; Comorbidity; | 2015 |
Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.
Topics: Allergens; Animals; Aspirin; Asthma; Blood Platelets; Bone Marrow Transplantation; Bronchoalveolar L | 2015 |
Outcomes of complete vs targeted approaches to endoscopic sinus surgery.
Topics: Aspirin; Asthma; Chronic Disease; Endoscopy; Female; Humans; Male; Middle Aged; Nasal Polyps; Postop | 2015 |
Long-term outcomes following functional endoscopic sinus surgery in Samter's triad.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Foll | 2015 |
Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarkers | 2015 |
Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline.
Topics: Anaphylaxis; Aspirin; Asthma; Chest Pain; Coronary Stenosis; Coronary Vessels; Electrocardiography; | 2015 |
Aspirin-Exacerbated Respiratory Disease--New Prime Suspects.
Topics: Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Homeostasis; Humans; Nas | 2016 |
Nonsteroidal anti-inflammatory-induced inhibition of signal transducer and activator of transcription 6 (STAT-6) phosphorylation in aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Cytokines; Drug Hype | 2016 |
Clinical Examination of Tissue Eosinophilia in Patients with Chronic Rhinosinusitis and Nasal Polyposis.
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Eosinophilia; Female; Humans; Male; Middle | 2016 |
The anti-inflammatory and pro-resolution effects of aspirin-triggered RvD1 (AT-RvD1) on peripheral blood mononuclear cells from patients with severe asthma.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Asthma; Cells, Cultured; Dermatophagoides pteronyssinus; | 2016 |
Clinical benefits of aspirin desensitization in patients with nonsteroidal anti-inflammatory drug exacerbated respiratory disease are not related to urinary eicosanoid release and are accompanied with decreased urine creatinine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Creatine; Desensitization, Immunolo | 2016 |
In Utero Exposure to Aspirin and Risk of Asthma in Childhood.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Cohort Studies; Female; Foll | 2016 |
Omalizumab in patient with aspirin exacerbated respiratory disease and chronic idiopathic urticaria.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Female; Human | 2017 |
Response to "The Role of Surgery in Management of Samter's Triad: A Systematic Review".
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Humans; Nasal Polyps; Sinusitis | 2017 |
Aspirin and asthma: barking up the right tree?
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans | 2008 |
Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis.
Topics: Administration, Oral; Adult; Age Factors; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Exp | 2008 |
[From wheezing to anaphylactic shock: allergology for your practice].
Topics: Adult; Allergy and Immunology; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2008 |
[Nonallergic diseases of the upper and lower airways].
Topics: Aspirin; Asthma; Bronchitis; Diagnosis, Differential; Drug Hypersensitivity; Eosinophilia; Humans; I | 2008 |
High-resolution computed tomography evaluation of peripheral airways in asthma patients: comparison of focal and diffuse air trapping.
Topics: Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Case-Control | 2009 |
Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Aspirin; Asthma; Bronchial Pr | 2008 |
Asthmatic reaction induced by Etoricoxib in a patient with aspirin-sensitive asthma.
Topics: Anaphylaxis; Aspirin; Asthma; Cyclooxygenase Inhibitors; Etoricoxib; Female; Humans; Middle Aged; Py | 2008 |
Obesity in aspirin-tolerant and aspirin-intolerant asthmatics.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aspirin; Asthma; Body Mass Index; Bron | 2008 |
Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Binding Sites; Child; Drug Hypersensiti | 2008 |
COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aspirin; | 2008 |
Selenium status in patients with aspirin-induced asthma.
Topics: Adult; Aged; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Asthma; Female; F | 2008 |
Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Cysteine; Dinoprost; Dr | 2008 |
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma.
Topics: Adult; Aged; Aspirin; Asthma; Cell Extracts; Chronic Disease; Dinoprostone; Drug Hypersensitivity; E | 2008 |
Otologic manifestations in Samter's syndrome.
Topics: Aspirin; Asthma; Chronic Disease; Cohort Studies; Drug Hypersensitivity; Ear Diseases; Ear, Middle; | 2009 |
Proteomics blood testing to distinguish chronic rhinosinusitis subtypes.
Topics: Aspirin; Asthma; Biomarkers; Chronic Disease; Diagnosis, Differential; Drug Hypersensitivity; Fungi; | 2008 |
Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma.
Topics: Adenosine Deaminase; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Case-Control Studies; Drug | 2009 |
Cellular allergen stimulation test with acetylsalicylic acid-lysine is not a useful test to discriminate between asthmatic patients with and without acetylsalicylic acid sensitivity.
Topics: Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Diagnosis, Differential; | 2009 |
Clinical significance of eosinophilic cationic protein levels in nasal secretions of patients with nasal polyposis.
Topics: Adult; Aged; Antimicrobial Cationic Peptides; Aspirin; Asthma; Drug Hypersensitivity; Eosinophilia; | 2009 |
Rational approach to aspirin dosing during oral challenges and desensitization of patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Oral; Adult; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Desensitization, | 2009 |
Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis.
Topics: Adult; Alleles; Aspirin; Asthma; Drug Hypersensitivity; Epistasis, Genetic; Female; Gene Frequency; | 2009 |
Chemokine CC-ligand 5 production and eosinophil activation into the upper airways of aspirin-sensitive patients.
Topics: Administration, Intranasal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chemoki | 2009 |
Asthmatic reaction induced by celecoxib in a patient with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Celecoxib; Cyclooxygenase Inhibitors; Drug Hypersensitivity | 2009 |
Aspirin-induced COX-2 overexpression in monocytes of aspirin-intolerant patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Drug Hypersensiti | 2009 |
[Chronic rhinosinusitis and aspirin intolerance].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Desensitization, I | 2009 |
Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma.
Topics: Adult; Aged; Algorithms; Artificial Intelligence; Aspirin; Asthma; Case-Control Studies; Cluster Ana | 2009 |
Anti-interleukin-5 therapy and severe asthma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aspirin; Asthma; Eosinophilia; Humans; In | 2009 |
[Self-desensitization with aspirin in a patient with aspirin intolerance].
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Pro | 2009 |
Theophylline again? Reasons for believing.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Bronchodilator Agents; Humans; Inflammation; Phosphoric D | 2009 |
Lack of association of ALOX12 and ALOX15 polymorphisms with aspirin-exacerbated respiratory disease in Korean patients.
Topics: Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Aspirin; Asthma; Bronchial Provocation T | 2009 |
Dose selection and dosing interval determination for LTRA use in asthma.
Topics: Aspirin; Asthma; Humans; Leukotriene Antagonists; Tablets | 2000 |
Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cell Line; Cyclooxygenase 2; Desensitizati | 2009 |
Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.
Topics: Aspirin; Asthma; Cell Line; Drug Hypersensitivity; Electrophoretic Mobility Shift Assay; Flow Cytome | 2009 |
Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; | 2010 |
Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease?
Topics: Adrenal Cortex Hormones; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Female; Forced Exp | 2009 |
A 19-month-old boy with recurrent respiratory distress.
Topics: Acid-Base Equilibrium; Albuterol; Alkalosis, Respiratory; Aspirin; Asthma; Bicarbonates; Bites, Huma | 2010 |
Aspirin allergy; its relationship to chronic intractable asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Hypersensitivity; Salicylates | 1947 |
Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers.
Topics: Adult; Aged; Anaphylaxis; Aspirin; Asthma; Biomarkers; Bleeding Time; Cysteine; Dinoprost; Eicosanoi | 2010 |
Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Disease Mod | 2010 |
Mediators of inflammation in nasal lavage from aspirin intolerant patients after aspirin challenge.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Chemokine CCL | 2010 |
Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis.
Topics: Adult; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Edema; Female; Humans; Laser-Doppler | 2010 |
Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Cohort Studies; Female; Humans; Male; Middle Aged; Polymor | 2010 |
Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Carrier Proteins; Drug Hypersensitivity; Fem | 2010 |
Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics.
Topics: Adult; Alleles; Arylamine N-Acetyltransferase; Asian People; Aspirin; Asthma; Case-Control Studies; | 2010 |
The prevalence of nasal polyps and the corresponding urinary LTE4 levels in severe compared to mild and moderate asthma.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Cohort Studies; Female; Humans; Leukotriene E4; Male; Midd | 2010 |
Airway responsiveness to inhaled aspirin is influenced by airway hyperresponsiveness in asthmatic patients.
Topics: Administration, Inhalation; Adolescent; Adult; Aspirin; Asthma; Asthma, Aspirin-Induced; Bronchial H | 2010 |
Aspirin sensitivity and the nose.
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Humans; Nasal Polyps; Respiration Disorders | 2010 |
Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Cell Nucleus; Chromosome Mapping; Drug Tolerance; Female; | 2010 |
Aspirin induced asthma accompanied with allergic bronchopulmonary aspergillosis: a case report.
Topics: Adult; Aspergillosis, Allergic Bronchopulmonary; Aspirin; Asthma; Humans; Male; Radiography, Thoraci | 2010 |
Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chromosome Mappin | 2010 |
A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Case-Control Studies; Chromosome Mapping; Co | 2011 |
Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmatics.
Topics: Adult; Aged; Aspirin; Asthma; Blood Cells; DNA Methylation; Drug Hypersensitivity; Female; Genome-Wi | 2011 |
Aspirin and nonsteroidal anti-inflammatory drug intolerance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Genetic Predispos | 2010 |
Have the efforts to prevent aspirin-related Reye's syndrome fuelled an increase in asthma?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; H | 2011 |
Recognising the risk of aspirin-sensitive respiratory disease in a patient with asthma who has previously tolerated aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Drug Tolerance; Hum | 2011 |
Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype.
Topics: Adolescent; Adult; Aspirin; Asthma; Bleeding Time; Breath Tests; Child; Child, Preschool; Chromatogr | 2011 |
A problem of rigidity.
Topics: Aspirin; Asthma; Biomedical Research; Chronic Disease; Comparative Effectiveness Research; Decision | 2011 |
MN community measurement responds.
Topics: Aspirin; Asthma; Biomedical Research; Comparative Effectiveness Research; Decision Support Technique | 2011 |
Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthma.
Topics: Adult; Aspirin; Asthma; Cells, Cultured; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Fi | 2011 |
Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Carrier Proteins; Drug Hypersensitivity; Female; Forced Ex | 2011 |
Aspirin desensitization for ASA triad patients--prospective study of the rhinologist`s perspective.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Drug | 2011 |
Epigenetic changes in B lymphocytes associated with house dust mite allergic asthma.
Topics: Animals; Antigens, CD19; Aspirin; Asthma; B-Lymphocytes; Case-Control Studies; Cytochrome P-450 Enzy | 2011 |
[The treatment of polypous suppurative rhinosinusitis in the patients presenting with the severe and moderate aspirin triad].
Topics: Aspirin; Asthma; Humans; Nasal Polyps; Rhinitis; Sinusitis; Suppuration | 2011 |
Obesity and aspirin intolerance are risk factors for difficult-to-treat asthma in Japanese non-atopic women.
Topics: Adult; Aged; Asian People; Aspirin; Asthma; Body Mass Index; Drug Hypersensitivity; Female; Humans; | 2012 |
Possible role of EMID2 on nasal polyps pathogenesis in Korean asthma patients.
Topics: Adolescent; Adult; Aged; Antigens, Surface; Asian People; Aspirin; Asthma; Drug Hypersensitivity; Fe | 2012 |
Potential association of DDR1 genetic variant with FEV1 decline by aspirin provocation in asthmatics.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Asthma, Aspirin-Induced; Bronchial Provocati | 2012 |
Challenge of isolated sputum cells supports in vivo origin of intolerance reaction to aspirin/non-steroidal anti-inflammatory drugs in asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Basophils; | 2012 |
Differential gene expression profile in PBMCs from subjects with AERD and ATA: a gene marker for AERD.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-I | 2012 |
Low SPINK5 expression in chronic rhinosinusitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; | 2012 |
Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease.
Topics: Adult; Arachidonate 15-Lipoxygenase; Asian People; Aspirin; Asthma; Asthma, Aspirin-Induced; Base Se | 2012 |
A possible association between ZNRD1 and aspirin-induced airway bronchoconstriction in a Korean population.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Bronchoconstriction; Cohort Studies; DNA-Bin | 2012 |
Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.
Topics: Animals; Aspirin; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Cy | 2012 |
Incidence of aspirin hypersensitivity in patients with chronic rhinosinusitis and diagnostic value of urinary leukotriene E4.
Topics: Adult; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Female; Humans; Leukotriene E4; Male | 2012 |
Aspirin sensitivity and coronary artery disease: implications for the practicing cardiologist.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Asthma; Chronic Disease; Coronary Artery Disease; Cyclooxyg | 2012 |
[Expressions of EOS and COX-2 in nasal polyps in patients with aspirin triad syndrome and its significance].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Endoscopy; Eosino | 2012 |
A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study.
Topics: Adolescent; Adult; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, | 2012 |
Aspirin-intolerant asthma in the Korean population: prevalence and characteristics based on a questionnaire survey.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchodilator Agents; Delive | 2013 |
Aspirin-intolerant asthma: role of cyclo-oxygenase enzymes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2002 |
Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Cysteine; Dinoprost; | 2002 |
[A case of asthma relieved by aspirin dialuminate].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Middle Aged | 2002 |
A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Drug Hypersensitivit | 2002 |
The effect of leukotriene-modifier drugs on aspirin-induced asthma and rhinitis reactions.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provoca | 2002 |
Disappearance of aspirin intolerance with antiasthma treatment.
Topics: Adolescent; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; | 2002 |
Aspirin-induced urticaria and angioedema, but not bronchoconstriction, associated with cysteinyl leukotriene overproduction in 2 patients with asthma.
Topics: Adult; Angioedema; Aspirin; Asthma; Bronchoconstriction; Humans; Leukotrienes; Middle Aged; Urticari | 2002 |
[Aspirin sensitivity: long term follow-up after up to 3 years of adaptive desensitization using a maintenance dose of 100 mg of aspirin a day].
Topics: Adolescent; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunol | 2002 |
Paracetamol use in pregnancy and wheezing in early childhood.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Asthma; Eczema; Female; Humans; Infant; Longitudin | 2002 |
Leukotriene receptors and aspirin sensitivity.
Topics: Aspirin; Asthma; Desensitization, Immunologic; Down-Regulation; Drug Hypersensitivity; Humans; Membr | 2002 |
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxyg | 2002 |
The natural history and clinical characteristics of aspirin-exacerbated respiratory disease.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocatio | 2002 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Inhalation; Administration, Intranasal; Adrenal Cortex Hormones; Aspirin; Asthma; Br | 2003 |
Presence of platelet-activating factor in nasal polyps and eosinophils.
Topics: Aspirin; Asthma; Chromatography, Thin Layer; Drug Hypersensitivity; Eosinophils; Humans; Leukocyte C | 2002 |
Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; | 2002 |
Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Chemotaxis; Female; | 2003 |
Transcriptional regulation of COX-2: a key mechanism in the pathogenesis of nasal polyposis in aspirin-sensitive asthmatics?
Topics: Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Hype | 2003 |
Nuclear factor-kappaB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors | 2003 |
Cyclooxygenase-2 inhibitors in aspirin-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2003 |
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge.
Topics: Adult; Aged; Aspirin; Asthma; Dinoprost; Female; Humans; Leukotriene E4; Male; Middle Aged; Prostagl | 2003 |
COX-2: Where are we in 2003? - Specific cyclooxygenase-2 inhibitors and aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2003 |
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinopros | 2003 |
Cyclooxygenase-2 inhibitors in aspirin-sensitive asthma.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase 2; | 2003 |
Bronchial mast cells are the dominating LTC4S-expressing cells in aspirin-tolerant asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Eosinophils; Female; Glutathione | 2003 |
Can NSAIDs intolerance disappear? A study of three cases.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Forced Expir | 2003 |
Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cyclooxygenase 2; | 2003 |
Effectiveness of multifaceted implementation of guidelines in primary care.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Asthma; Bronchodilator Agents; Drug Utilizati | 2003 |
Glutathione peroxidase activity in blood cells from aspirin-induced asthma patients.
Topics: Adult; Aged; Aspirin; Asthma; Blood Cells; Case-Control Studies; Female; Glutathione Peroxidase; Hum | 2003 |
[Study of cellular inflammatory response with bronchoalveolar lavage in allergic asthma, aspirin asthma and in extrinsic infiltrating alveolitis].
Topics: Adult; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bro | 2002 |
[A few clarifications on the subject of acetylsalicylic acid therapy in asthma].
Topics: Aspirin; Asthma; Humans | 1954 |
[Allergy to aspirin in patients with asthma].
Topics: Aspirin; Asthma; Humans; Hypersensitivity; Immune System Diseases | 1954 |
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Tolerance; | 2003 |
[Allergy to aspirin. Gastric nemorrnages preceding the appearance of asthma, urticaria or Quincke's edema].
Topics: Angioedema; Aspirin; Asthma; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Hypersensitivity; Urti | 1960 |
[TREATMENT OF BRONCHIAL ASTHMA IN CHILDREN].
Topics: Ascorbic Acid; Aspirin; Asthma; Cell- and Tissue-Based Therapy; Child; Ephedrine; Immunotherapy, Act | 1963 |
[THE EFFECT OF ANTIPYRETIC AND ANALGESIC SUBSTANCES ON HUMAN BRONCHIAL ASTHMA AND EXPERIMENTAL ASTHMA IN GUINEA PIGS].
Topics: Acetylcholine; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anaphylaxis; Animals; Antipyretics | 1963 |
[THE EFFECT OF BRADYKININ AEROSOL ON THE RESPIRATION OF HUMANS AND GUINEA PIGS AND THE INFLUENCE OF VARIOUS SUBSTANCE ON EXPERIMENTAL BRADYKININ BRONCHOSPASM].
Topics: Aerosols; Aminopyrine; Animals; Aspirin; Asthma; Atropine; Bradykinin; Bronchial Spasm; Guinea Pigs; | 1963 |
[IS ASPIRIN A DANGEROUS DRUG?].
Topics: Anemia; Anemia, Hypochromic; Angioedema; Anticoagulants; Aspirin; Asthma; Blood Coagulation Disorder | 1963 |
ASPIRIN-INDUCED BRONCHIAL ASTHMA. A DIAGNOSTIC PROBLEM.
Topics: Aminophylline; Aspirin; Asthma; Chlorothiazide; Diagnosis, Differential; Diuretics; Epinephrine; Hea | 1964 |
[DRUG ALLERGY IN PATIENTS SUFFERING FROM ALLERGIC DISEASES WITH IMMEDIATE REACTION].
Topics: Anaphylaxis; Anti-Bacterial Agents; Aspirin; Asthma; Barbiturates; Codeine; Drug Eruptions; Drug Hyp | 1964 |
Prevalence of asthma with aspirin hypersensitivity in the adult population of Poland.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Child, Pre | 2003 |
[Exacerbation of aspirin-induced asthma associated with RSV infection].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Middle Aged; Respiratory S | 2003 |
Characterization of six base pair deletion in the putative HNF1-binding site of human PXR promoter.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Base Pairing; Binding Sites; DNA; DNA-Bind | 2003 |
RANTES, eotaxin and eotaxin-2 expression and production in patients with aspirin triad.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Chemokine CCL11; Chemokine CCL24; Chemokine CCL5; C | 2003 |
Subclinical aspirin sensitivity in subjects with nasal polyposis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female | 2003 |
[Antileukotrienes in the therapy of bronchial asthma].
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Aspirin; Asthma; Asthma, E | 2003 |
[Urinary leukotriene E4 concentration in patients with bronchial asthma and intolerance of non-steroids anti-inflammatory drugs before and after oral aspirin challenge].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; | 2003 |
Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase.
Topics: 5-Lipoxygenase-Activating Proteins; Alleles; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Base Sequ | 2004 |
Clinical features of asthmatic patients with increased urinary leukotriene E4 excretion (hyperleukotrienuria): Involvement of chronic hyperplastic rhinosinusitis with nasal polyposis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Contr | 2004 |
Allergy to aspirin.
Topics: Aspirin; Asthma; Humans; Hypersensitivity | 1951 |
[Hypersensitivity to aspirin in bronchial asthma].
Topics: Aspirin; Asthma; Humans; Hypersensitivity | 1951 |
Clinical relevance of nasal polyps in individuals recruited from a general population-based study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Cross-Sectional Studies; Drug Hypersensitivity; Fem | 2004 |
HLA association in aspirin-intolerant asthma: DPB1*0301 as a strong marker in a Korean population.
Topics: Adult; Alleles; Aspirin; Asthma; Case-Control Studies; Female; Gene Frequency; Genetic Markers; Hapl | 2004 |
Aspirin intolerance and allergy to house dust mites: important factors associated with development of severe asthma.
Topics: Adolescent; Adult; Age Factors; Aged; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; A | 2004 |
Aspirin induced asthma: clinical relevance of finding was not explained.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans | 2004 |
Aspirin induced asthma: effect size needs to be clarified.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans | 2004 |
Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspirin; Asthma; Australia; Case-Control Studie | 2004 |
Non-specific bronchial hyperresponsiveness is a risk factor for steroid insensitivity in nasal polyposis.
Topics: Administration, Oral; Aerosols; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti | 2004 |
Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Test | 2004 |
Effect of inhalation aspirin challenge on exhaled nitric oxide in patients with aspirin-inducible asthma.
Topics: Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Breath Tests; Double-Blind Method; Eosinop | 2004 |
Severe asthma attacks after sexual intercourse.
Topics: Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Co | 2004 |
Increase in urinary leukotriene B4 glucuronide concentration in patients with aspirin-intolerant asthma after intravenous aspirin challenge.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Glucu | 2004 |
Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Enterotoxins; Eosinophi | 2004 |
Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; I | 2004 |
The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophil Degra | 2004 |
Thwarting an aspirin allergy. Aspirin can trigger allergy and asthma symptoms. Careful desensitization can hold them at bay.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Drug Hyperse | 2004 |
The HLA-DPB1*0301 marker might predict the requirement for leukotriene receptor antagonist in patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Drug Hypersensitivity; Female; Genetic Markers; HLA-D | 2004 |
Dynamics of COX-2 in nasal mucosa and nasal polyps from aspirin-tolerant and aspirin-intolerant patients with asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase 2; | 2004 |
Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis.
Topics: Adult; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Enterotoxins; Female; Humans; Immuno | 2004 |
Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach.
Topics: Aspirin; Asthma; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; Gene Exp | 2004 |
Asthma, hypersensitivity, and coitus.
Topics: Aspirin; Asthma; Coitus; Follow-Up Studies; Humans; Male; Middle Aged; Respiratory Hypersensitivity; | 2004 |
A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxyge | 2004 |
Leukotriene CysLT1-receptor antagonism and nasal lysine-aspirin provocation in aspirin-induced asthma.
Topics: Aspirin; Asthma; Humans; Leukotriene Antagonists; Lysine; Membrane Proteins; Nasal Mucosa; Nasal Pro | 2005 |
Myocardial infarction after aspirin treatment.
Topics: Aspirin; Asthma; Coronary Angiography; Coronary Vasospasm; Echocardiography; Female; Fibrinolytic Ag | 2005 |
Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As | 2005 |
Exhaled eicosanoids following oral aspirin challenge in asthmatic patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Asthma; Biomarkers; Breat | 2004 |
[Widal triad (Asthma-Nasal polyposis-aspirin intolerance): an inflammatory metabolism abnormality].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Metabolic Diseases; Nasal Polyps | 2005 |
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Binding Sites; Child; Child, P | 2005 |
Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma.
Topics: Adult; Aspirin; Asthma; Cell Count; Drug Hypersensitivity; Eosinophils; Epithelial Cells; Female; Hu | 2005 |
Fibrous dysplasia of middle turbinate associated with Widal syndrome: endoscopic treatment of a rare case.
Topics: Adult; Aspirin; Asthma; Diagnosis, Differential; Drug Hypersensitivity; Endoscopy; Fibrous Dysplasia | 2004 |
Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness.
Topics: 5-Lipoxygenase-Activating Proteins; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Carrier Proteins; | 2005 |
Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma.
Topics: Adult; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Asthm | 2005 |
A teenager with severe asthma exacerbation following ibuprofen.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Contraindications; Humans; Ibu | 2005 |
Improvements in an oral aspirin challenge protocol for the diagnosis of aspirin hypersensitivity.
Topics: Administration, Oral; Adult; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2005 |
Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2005 |
Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease.
Topics: Adult; Aspirin; Asthma; Case-Control Studies; Chronic Disease; Cohort Studies; Drug Hypersensitivity | 2005 |
Characterisation of patients with frequent exacerbation of asthma.
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As | 2006 |
Characterisation of patients with frequent exacerbation of asthma.
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As | 2006 |
Characterisation of patients with frequent exacerbation of asthma.
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As | 2006 |
Characterisation of patients with frequent exacerbation of asthma.
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As | 2006 |
The impact of asthma and aspirin sensitivity on quality of life of patients with nasal polyposis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Male; Middle | 2005 |
Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopy.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Australia; Cyclooxygenase 1; Cyclooxygenase Inhibit | 2005 |
Aspirin-triggered 15-HETE generation in peripheral blood leukocytes is a specific and sensitive Aspirin-Sensitive Patients Identification Test (ASPITest).
Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Hydroxyeicosatetraenoic Acids; | 2005 |
Contribution of aspirin-intolerant asthma to near fatal asthma based on a questionnaire survey in Niigata Prefecture, Japan.
Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Emerge | 2005 |
Early presentation with angioedema and urticaria in cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs among young, Asian, atopic children.
Topics: Acetaminophen; Administration, Oral; Adolescent; Allergens; Angioedema; Anti-Inflammatory Agents, No | 2005 |
Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma.
Topics: Adolescent; Adult; Airway Obstruction; Anti-Asthmatic Agents; Aspirin; Asthma; Case-Control Studies; | 2005 |
The blocking effect of essential controller medications during aspirin challenges in patients with aspirin-exacerbated respiratory disease.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Inflammatory Agents, N | 2005 |
Complement C3a and C4a increased in plasma of patients with aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Complement C3a; Complement C4a; Fem | 2006 |
Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma.
Topics: Adult; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Fema | 2005 |
Comparison of plasma eotaxin family level in aspirin-induced and aspirin-tolerant asthma patients.
Topics: Adult; Aspirin; Asthma; Chemokine CCL11; Chemokine CCL24; Chemokine CCL26; Chemokines, CC; Enzyme-Li | 2005 |
Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population.
Topics: Adult; Aspirin; Asthma; Female; Glutathione Transferase; Humans; Korea; Male; Middle Aged; Polymorph | 2006 |
[Nasal polyps is not a homogenous pathology].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Eosino | 2005 |
Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population.
Topics: 5-Lipoxygenase-Activating Proteins; Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Carrier Pro | 2005 |
Asthma attacks induced by low doses of celecoxib, aspirin, and acetaminophen.
Topics: Acetaminophen; Aspirin; Asthma; Celecoxib; Cyclooxygenase Inhibitors; Female; Humans; Leukotriene E4 | 2006 |
[New pathophysiological concepts on aspirin hypersensitivity (Widal syndrome); diagnostic and therapeutic consequences].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Drug Hypersensitiv | 2005 |
Aspirin induced asthma (AIA) with nasal polyps has the highest basal LTE4 excretion: a study vs AIA without polyps, mild topic asthma, and normal controls.
Topics: Adult; Aspirin; Asthma; Biomarkers; Bronchial Provocation Tests; Humans; Leukotriene E4; Middle Aged | 2006 |
Does it make sense to "desens"? Aspirin desensitization in the treatment of chronic rhinosinusitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Desensitization, Immunolo | 2006 |
Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma.
Topics: Adolescent; Adult; Aged; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Cyclooxygenase Inhibitors; Eo | 2006 |
Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males.
Topics: Adult; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Drug | 2006 |
[Hypersensitivity reaction to systemic corticosteroids in a hemodialysis patients].
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Aspirin; Asthma; Bronchial Spasm; Desensitization, Immu | 2006 |
Changes in urinary LTE4 and nasal functions following nasal provocation test with ASA in ASA-tolerant and -intolerant asthmatics.
Topics: Administration, Intranasal; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; F | 2006 |
Circulating autoantibodies in patients with aspirin-intolerant asthma: an epiphenomenon related to airway inflammation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Autoantibodies; Bronchi; Case-Contro | 2006 |
A polymorphism of MS4A2 (- 109T > C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FcepsilonR1beta) is associated with a susceptibility to aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Aspirin; Asthma; Bronchial Pr | 2006 |
Influence of allergy on the symptoms and treatment of nasal polyposis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Beclomethasone; Bronchial Provocation Test | 2006 |
Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Gene | 2007 |
Association of TNF-alpha genetic polymorphism with HLA DPB1*0301.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Gene | 2006 |
Mechanisms of aspirin-sensitive respiratory disease--a two-compartment model.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Cyclooxygenas | 2007 |
Different eicosanoid profile of the hypersensitivity reactions triggered by aspirin and celecoxib in a patient with sinusitis, asthma, and urticaria.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Drug Hypersensitivity; E | 2006 |
ADAM33 polymorphisms are associated with aspirin-intolerant asthma in the Japanese population.
Topics: ADAM Proteins; Aged; Anti-Inflammatory Agents, Non-Steroidal; Asian People; Aspirin; Asthma; Drug To | 2007 |
Aspirin and decreased adult-onset asthma: randomized comparisons from the physicians' health study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Female; Humans; Male; Middle Aged; Physicians; Risk | 2007 |
Novel exon 2A of the high-affinity receptor for the IgE alpha-chain gene (FCER1A) and autoimmunity in patients with asthma or urticaria.
Topics: Adult; Aspirin; Asthma; Autoimmunity; DNA Mutational Analysis; Drug Hypersensitivity; Exons; Female; | 2006 |
Eicosanoids, aspirin-intolerance and the upper airways--current standards and recent improvements of the desensitization therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Clinical Trials as Topic | 2006 |
I have asthma, and my doctor cautions against taking aspirin. Why?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Contraindications; Drug Hypersensitivity; | 2007 |
Aspirin challenge and desensitization for aspirin-exacerbated respiratory disease: a practice paper.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Drug Hyperse | 2007 |
Bronchodilators, fatal asthma, rebound effect and similitude.
Topics: Antidepressive Agents; Aspirin; Asthma; Bronchial Spasm; Bronchodilator Agents; Evidence-Based Medic | 2007 |
The relationship between historical aspirin-induced asthma and severity of asthma induced during oral aspirin challenges.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cohort Studies; Dose-Response Relat | 2007 |
Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.
Topics: Adult; Alleles; Aspirin; Asthma; Case-Control Studies; Drug Tolerance; Female; Gene Frequency; Genot | 2007 |
Alternative splicing of cyclooxygenase-1 gene: altered expression in leucocytes from patients with bronchial asthma and association with aspirin-induced 15-HETE release.
Topics: Adult; Aged; Alternative Splicing; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cycloox | 2007 |
Analysis of perimenstrual asthma based on questionnaire surveys in Japan.
Topics: Adult; Aspirin; Asthma; Female; Health Surveys; Humans; Japan; Menstrual Cycle; Middle Aged; Severit | 2007 |
Deficiency of cyclooxygenases transcripts in cultured primary bronchial epithelial cells of aspirin-sensitive asthmatics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Cells, Cultured; Cyclooxygenase 1; Cycl | 2007 |
Urinary LTE4 is higher after nasal provocation test with L-ASA in bronchial than in only nasal responders.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Cysteine; Female; Forced Expiratory Volume; Human | 2007 |
Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity.
Topics: Adult; Aspirin; Asthma; Case-Control Studies; Diagnosis, Differential; Drug Hypersensitivity; Female | 2007 |
The prevalence of Samter's triad in patients undergoing functional endoscopic sinus surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Child, Preschool; Chronic Diseas | 2007 |
An economic analysis of aspirin desensitization in aspirin-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Clopidogre | 2008 |
Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Lipoxins; Male; Middle Aged; Severity | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma | 2007 |
CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Drug Hypersensitivity; Forced Expir | 2007 |
Galectin-10 mRNA is overexpressed in peripheral blood of aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Biomarkers; Case-Control Studies; Drug Hypersensitivity; Female; Galectins; | 2008 |
Systemic responses after bronchial aspirin challenge in sensitive patients with asthma.
Topics: Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bone Ma | 2008 |
[Melatonin production in thrombocytes and their functional activity in patients with aspirin asthma].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Platelets; Circadian Rhythm; | 2007 |
Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics.
Topics: Adult; Aspirin; Asthma; Female; Genetic Predisposition to Disease; Humans; Korea; Male; Pneumonia; P | 2008 |
Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma.
Topics: Adipokines; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Carrier Proteins; Chrom | 2008 |
[ASA-intolerance (Samter's syndrome): an important differential diagnosis for chronic airway diseases].
Topics: Aspirin; Asthma; Chronic Disease; Diagnosis, Differential; Drug Hypersensitivity; Humans; Nasal Poly | 2008 |
Involvement of 15-lipoxygenase and prostaglandin EP receptors in aspirin-triggered 15-hydroxyeicosatetraenoic acid generation in aspirin-sensitive asthmatics.
Topics: Adolescent; Adult; Aged; Arachidonate 15-Lipoxygenase; Aspirin; Asthma; Caffeic Acids; Dinoprostone; | 2008 |
Sinonasal outcomes after endoscopic sinus surgery in asthmatic patients with nasal polyps: a difference between aspirin-tolerant and aspirin-induced asthma?
Topics: Adult; Aspirin; Asthma; Bleeding Time; Drug Hypersensitivity; Endoscopy; Female; Humans; Male; Middl | 2008 |
Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthma.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Australia; Case-Control Studies; Cyclooxygenase 2; | 2008 |
Bronchial asthma induced by indomethacin.
Topics: Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged; | 1967 |
Aspirin-induced bronchial asthma.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; | 1967 |
Inhibition by ketotifen of idiosyncratic reactions to aspirin.
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; Histamine H1 Antago | 1980 |
Lipoxygenase pathway and hydroperoxy acids: possible relevance to aspirin-induced asthma and hyperirritability of airways in asthmatics.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acids; Aspirin; Asthma; Autacoids; Humans; L | 1981 |
Cross-desensitization between aspirin and benzoate in asthma.
Topics: Adolescent; Aspirin; Asthma; Benzoates; Cross Reactions; Desensitization, Immunologic; Female; Human | 1983 |
Ultrastructural and functional studies of cilia from patients with asthma, aspirin intolerance, and nasal polyps.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adolescent; Adult; Aspirin; Asthma; Cells, Cultur | 1983 |
Qualifying factors in the classification of asthma: how valuable they are to the clinician.
Topics: Animals; Aspirin; Asthma; Dogs; Drug Hypersensitivity; History, 17th Century; History, 19th Century; | 1983 |
Analgesic-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma | 1983 |
[Analgetic drug intolerance].
Topics: Analgesics; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Complement Activation; Drug Hypers | 1983 |
Anti-cyclo-oxygenase agents and asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Asthma; Bronchi; Cyclooxygenase | 1983 |
Possible mechanisms underlying mucus secretion in aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Bronchi; Humans; Lipoxygenase; Models, Biological; Mucus; Prostaglandins | 1983 |
Asthma and anti-inflammatory drugs. Mechanisms and clinical patterns.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Humans; Lung | 1983 |
Proctocolitis induced by salicylate and associated with asthma and recurrent nasal polyps.
Topics: Aspirin; Asthma; Colitis; Double-Blind Method; Drug Hypersensitivity; Humans; Male; Middle Aged; Nas | 1983 |
HLA DR typing of aspirin sensitive asthmatics.
Topics: Aspirin; Asthma; Bronchial Spasm; Disease Susceptibility; Drug Hypersensitivity; Female; Genes, MHC | 1984 |
Effect of aspirin in "aspirin sensitive" patients.
Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Dinoprost; Dinoprostone; Female; Hu | 1984 |
Identification and characterization of neutrophil chemotactic activity in aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, Gel; Chrom | 1984 |
[Inhalation provocation test with lysine acetylsalicylic acid (Aspisol)--a useful method for the diagnosis of analgesic asthma].
Topics: Airway Resistance; Analgesics; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Drug Hypersens | 1984 |
Neutrophil chemotactic factor of anaphylaxis (NCF-A) release in aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Chemotactic Factors; Cromolyn Sodium; Drug Hypersensitivity; Female; Forced | 1984 |
Diagnosis, prevention, and treatment of adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs.
Topics: Angioedema; Anti-Inflammatory Agents; Aspirin; Asthma; Cross Reactions; Cyclooxygenase Inhibitors; D | 1984 |
Free histamine in nasal polyp fluid.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Extracellular Space; Histamine; Humans; Hypersensitivity; Na | 1984 |
Clinical profile and recurrence of nasal polyps.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Eczema; Female; Humans; Male; Middl | 1984 |
Effects of chronic aspirin ingestion in aspirin-intolerant asthmatic patients.
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Asthma; Dose-Response Relationship, Drug; Drug Hyp | 1984 |
[Types of bronchial reaction to analgesics].
Topics: Aspirin; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Lung Volu | 1984 |
Diagnosis of intolerance to food additives.
Topics: Administration, Oral; Antigens; Aspirin; Asthma; Female; Food Additives; Food Hypersensitivity; Huma | 1984 |
Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Expiratory Vo | 1984 |
[Aspirin-induced asthma].
Topics: Aspirin; Asthma; Humans | 1984 |
[Indications for the aspirin provocation test in the asthmatic].
Topics: Adult; Aspirin; Asthma; Benzoates; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Human | 1984 |
[Tartrazine hypersensitivity in patients with asthma and aspirin hypersensitivity].
Topics: Adult; Aspirin; Asthma; Azo Compounds; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Tar | 1984 |
Premenstrual exacerbation of asthma.
Topics: Adolescent; Adult; Aspirin; Asthma; Contraceptives, Oral; Female; Humans; Menstrual Cycle; Middle Ag | 1984 |
The terrible triad--asthma, nasal polyps, and sensitivity to aspirin.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Male; Nasal Polyps; Syndrome | 1983 |
Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs. II. Action of aspirin and salicylic acid in antagonizing mediators of allergic asthma.
Topics: Animals; Aspirin; Asthma; Bradykinin; Dinoprost; Guinea Pigs; Histamine; Mechanoreceptors; Muscle, S | 1984 |
The absence of detectable complement activation in aspirin-sensitive asthmatic patients during aspirin challenge.
Topics: Adult; Aged; Aspirin; Asthma; Complement Activation; Complement C4; Female; Humans; Immunoelectropho | 1983 |
Primary nasal polyposis.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Child; Female; HLA Antigens; | 1983 |
Aspirin desensitization in aspirin-sensitive asthma: failure to maintain a desensitized state during prolonged therapy.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Female; Humans | 1983 |
[Aspirin-induced asthma and analysis of the aspirin triad in 30 cases].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Child; Female; Humans; Male; Middle Age | 1983 |
Analgesic induced asthma.
Topics: Acute Disease; Adolescent; Adult; Analgesics; Aspirin; Asthma; Female; Humans; Hydrocortisone; Male | 1983 |
[Severe asthma attack in a patient with intrinsic aspirin-sensitive bronchial asthma induced by intravenous administration of steroid].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Male; Prednisolone | 1984 |
Hypersensitivity to non-steroidal anti-inflammatory drugs--asthma precipitated by zomepirac. A case report.
Topics: Analgesics; Aspirin; Asthma; Humans; Male; Middle Aged; Pyrroles; Time Factors; Tolmetin | 1984 |
Aspirin-sensitive asthma and rhinosinusitis: current concepts and recent advances.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Tolerance; Humans; Rhinitis; Sinusitis | 1984 |
Pathogenesis of asthma.
Topics: Adult; Air Pollution; Allergens; Animals; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Bronch | 1984 |
[Bronchial asthma, nasal polyposis and analgesic intolerance (the ASA triad). A successful computer based analysis of free texts].
Topics: Analgesics; Aspirin; Asthma; Chronic Disease; Computers; Drug Tolerance; Humans; Nasal Polyps; Rhini | 1984 |
Aspirin tolerance induced in aspirin-sensitive asthmatics.
Topics: Aspirin; Asthma; Cross Reactions; Dose-Response Relationship, Drug; Dose-Response Relationship, Immu | 1984 |
Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma.
Topics: Adolescent; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Child; Child, Preschool; | 1984 |
Decreased sensitivity to tartrazine after aspirin desensitization in an asthmatic patient intolerant to both aspirin and tartrazine.
Topics: Adult; Aspirin; Asthma; Azo Compounds; Desensitization, Immunologic; Drug Hypersensitivity; Female; | 1984 |
[IgE in patients with asthma and hypersensitivity to aspirin].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hypergammaglobulinemia; Immunoglobulin E; Mid | 1984 |
Aspirin desensitization in aspirin-sensitive asthma: failure to maintain a desensitized state during prolonged therapy.
Topics: Adult; Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Female; Humans; Indomethacin; | 1984 |
Epithelial damage in nasal polyps.
Topics: Adult; Aspirin; Asthma; Cystic Fibrosis; Drug Hypersensitivity; Epithelium; Female; Humans; Male; Mi | 1984 |
[Ketotifen in the treatment of hypersensitivity to acetylsalicylic acid].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Ketotifen; Male; Middle Aged | 1984 |
Drug-induced asthma: a review.
Topics: Alfaxalone Alfadolone Mixture; Aspirin; Asthma; Azo Compounds; Bronchial Spasm; Coloring Agents; Con | 1980 |
Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Constriction, Pathologic; Guinea Pigs; Histamine; Hyper | 1980 |
Clinical aspects of bronchial asthma.
Topics: Aspirin; Asthma; Carbon Dioxide; Environmental Pollutants; Humans; Medical History Taking; Oxygen; P | 1980 |
[Prevention of food hypersensitivities with aspirin].
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Food Hypersensitivity; Ibuprofen; Indomethacin; Milk; P | 1980 |
Aspirin sensitivity in asthmatics.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1981 |
[Inhalation provocation test with lysine-acetylsalicylic acid in patients with analgetics-induced asthma (author's transl)].
Topics: Adolescent; Adult; Analgesics; Aspirin; Asthma; Bronchial Provocation Tests; Female; Humans; Lysine; | 1982 |
Potentiation by acetylsalicylic acid of skin weal response to compound 48/80 in ASA-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Drug Synergism; Histamine; Humans; Injections, Intradermal; p-Methoxy-N-meth | 1983 |
[The use of guacetisal in bronchopulmonary pathology in children].
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Bronchial Diseases; Bronchitis; Bronchopneumonia; Child; | 1983 |
Improvement in aspirin-sensitive asthmatic subjects after rapid aspirin desensitization and aspirin maintenance (ADAM) treatment.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; | 1983 |
Aspirin-sensitive rhinosinusitis/asthma: spectrum of adverse reactions to aspirin.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Forced Exp | 1983 |
Asthma and severe drug-related problems.
Topics: Aspirin; Asthma; Autobiographies as Topic; Child; Female; Humans | 1983 |
Desensitization of aspirin-sensitive asthmatics: a therapeutic alternative?
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Huma | 1983 |
Acetaminophen and aspirin challenges in subgroups of asthmatics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anaphylaxis; Aspirin; Asthma; Bronchial Provocation Tests; D | 1983 |
Reviewing bronchial asthma and its pharmacotherapy.
Topics: Adult; Aged; Aspirin; Asthma; Bronchodilator Agents; Female; Humans; Male; Patient Education as Topi | 1983 |
[Wrong treatment of asthma patient].
Topics: Aspirin; Asthma; Humans; Jurisprudence; Male; Medication Errors; Middle Aged; Myocardial Infarction; | 1980 |
Bronchial exercise and oral challenge procedures.
Topics: Adult; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Child; Drug Hypersens | 1981 |
Analgesics and asthma.
Topics: Alprostadil; Analgesics; Aspirin; Asthma; Dinoprost; Dinoprostone; Drug Hypersensitivity; Humans; Pr | 1982 |
[Asthma associated with analgesics (author's transl)].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Complement Activation; Drug Hyperse | 1980 |
Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Dose-Response Relationship, | 1982 |
Aspirin-induced asthma in children.
Topics: Acetylation; Adolescent; Anti-Inflammatory Agents; Aspirin; Asthma; Child; Complement System Protein | 1982 |
Asthma in the elderly: special challenge.
Topics: Adrenal Cortex Hormones; Aged; Aspirin; Asthma; Diagnosis, Differential; Humans; Lung Diseases, Obst | 1982 |
Reactions to acetylsalicylic acid.
Topics: Adult; Anaphylaxis; Aspirin; Asthma; Canada; Drug Labeling; Female; Humans; Middle Aged; Nonprescrip | 1982 |
Comparison of three prick test methods with the intradermal test and with the rast in the diagnosis of mite allergy.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Child; Drug Hypersensitivity; Humans; Hypersensitivity; Im | 1982 |
Tartrazine: a potentially hazardous dye in Canadian drugs.
Topics: Aspirin; Asthma; Azo Compounds; Canada; Drug Hypersensitivity; Food Coloring Agents; Humans; Tartraz | 1982 |
Tartrazine and benzoate challenge and dietary avoidance in chronic asthma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aspirin; Asthma; Azo Compounds; Benzoates; Chronic Disease; Fe | 1982 |
Refractory period to aspirin after aspirin-induced asthma.
Topics: Aspirin; Asthma; Humans; Ketotifen | 1982 |
Treatment of aspirin idiosyncracy.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1982 |
Aspirin and asthma.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans | 1982 |
Evaluation of intolerance to analgesics, preservatives and food colorants with challenge tests.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Child; False Negative Reactio | 1982 |
[Does benoxaprofen permit the prevention of acetylsalicylic acid asthma].
Topics: Aspirin; Asthma; Humans; Propionates | 1982 |
[Case of aspirin-sensitive asthma with an anaphylactoid reaction to hydrocortisone sodium succinate which has been effective in relieving acute symptoms].
Topics: Adult; Anaphylaxis; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hydrocortisone; Male; Time Facto | 1982 |
[Development of aspirin tolerance in patients with asthma and aspirin hypersensitivity].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged | 1982 |
[Venous blood histamine level during aspirin-induced bronchial spasm].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forearm; Histami | 1980 |
Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma.
Topics: Animals; Aspirin; Asthma; Atropine; Disease Models, Animal; Dogs; Female; Indomethacin; Male; Muscle | 1981 |
Histaminemia after aspirin challenge in aspirin-sensitive asthmatics.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Forced Expiratory Volume; Hist | 1981 |
[Probable non-reagin mechanism of house-dust allergy in patients with asthma and hypersensitivity to aspirin].
Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Dust; Humans; Middle Aged | 1980 |
Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Dexamethasone; Female; Forced Expiratory Volume; Humans; Hy | 1981 |
[Differences in the course of exercise-induced bronchial spasm in pollen asthma and bronchial asthma with aspirin hypersensitivity].
Topics: Adolescent; Adult; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Diagnosis | 1981 |
[Hypersensitivity to pyrazolone drugs (author's transl)].
Topics: Adolescent; Adult; Aged; Anaphylaxis; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; | 1981 |
[Acetylsalicylic acid and food additive intolerance in urticaria, bronchial asthma and rhinopathy].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Child; Drug Hypersensitivity; Female; Food Additives; Food | 1981 |
[Asthma caused by inhibitors of prostaglandin synthesis].
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Bronchial Spasm; Humans; Prostaglandin Antagonists | 1981 |
Aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Drug Tolerance; Humans | 1981 |
[Bronchomotor manifestations caused by acetylsalicylic acid. Research on a group of children with allergic asthma].
Topics: Aspirin; Asthma; Child; Female; Humans; Lung; Male; Respiratory Function Tests; Rhinitis, Allergic, | 1981 |
[Aspirin asthma].
Topics: Aspirin; Asthma; Drug Tolerance; Female; Humans; Male; Nasal Polyps; Platelet Aggregation; Purpura | 1980 |
[Hypersensitivity to acetysal in bronchial asthma].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Spasm; Chronic Disease; Drug Hypersensitivity; F | 1980 |
[ASA-triad syndrome in a 21-year-old woman in the 24th week of pregnancy].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Nasal Polyps; Pregnancy; Pregnancy Co | 1980 |
Aspirin, prostaglandins, and bronchial asthma.
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Female; Humans; Male; Middle Aged; Prostaglandins | 1980 |
ASA desensitization offers dual benefit to asthmatics.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Male; M | 1980 |
[Aspirin-induced asthmatic syndrome].
Topics: Adolescent; Allergens; Aspirin; Asthma; Diagnosis, Differential; Drug Hypersensitivity; Humans; Male | 1980 |
Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Desensitization, Immunologic; | 1980 |
[Aetiological mechanism and its treatment of bronchial asthma (author's transl)].
Topics: Allergens; Aspirin; Asthma; Asthma, Exercise-Induced; Female; Humans; Male | 1980 |
Sulfinpyrazone and aspirin-induced asthma.
Topics: Anaphylaxis; Aspirin; Asthma; Bronchial Spasm; Dipyrone; Drug Hypersensitivity; Humans; Sulfinpyrazo | 1980 |
Inhibition of idiosyncratic reactions to aspirin by ketotifen.
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Ketotifen; Piperidines; Thio | 1980 |
[Aspirin intolerance in patients with nasal polyps and bronchial asthma].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Drug Interactions; Female; Humans; | 1980 |
Is tartrazine-induced asthma related to inhibition of prostaglandin biosynthesis?
Topics: Aspirin; Asthma; Azo Compounds; Blood Platelets; Humans; Platelet Aggregation; Prostaglandins; Sulfa | 1980 |
Aspirin sensitivity in asthmatics.
Topics: Adult; Aspirin; Asthma; Child; Drug Hypersensitivity; Humans | 1980 |
Severe asthma induced by naproxen--a case report and review of the literature.
Topics: Acute Disease; Arthritis; Aspirin; Asthma; Bronchial Spasm; Humans; Male; Middle Aged; Naproxen; Pro | 1980 |
Aspirin allergy.
Topics: Adolescent; Adult; Age Factors; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Fem | 1981 |
[Serum phospholipase A2 activity in patients with aspirin-induced asthma].
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Hu | 1995 |
[An adult case of rice-induced asthma with aspirin idiosyncrasy].
Topics: Aspirin; Asthma; Drug Eruptions; Drug Hypersensitivity; Food Hypersensitivity; Humans; Male; Middle | 1995 |
Acetaminophen, some other drugs, some diseases and the risk of transitional cell carcinoma. A population-based case-control study.
Topics: Acetaminophen; Age Factors; Analgesics; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Aspir | 1995 |
In vitro release of arachidonic acid metabolites, glutathione peroxidase, and oxygen-free radicals from platelets of asthmatic patients with and without aspirin intolerance.
Topics: Adult; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Chromatography, High Pressure Liquid; Dru | 1995 |
[Examination on aspirin-induced asthma and hypersensitivity to steroids--a questionnaire to 850 asthma on hypersensitivity to non-steroidal anti-inflammatory drugs and hypersensitivity to steroids].
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Asthma; Child; Child, Preschool; Contraindications; Drug H | 1995 |
Inhibition of monocyte leukotriene B4 production after aspirin desensitization.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Female; Humans; Leukotriene B4; Leukotriene C4 | 1995 |
Lipoxygenase inhibitor-provoked acute asthma in a patient with asthma relieved by aspirin.
Topics: Acute Disease; Aspirin; Asthma; Benzoquinones; Humans; Lipoxygenase Inhibitors; Male; Middle Aged | 1995 |
Aspirin intolerance.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1995 |
[Treatment of 36 corticosteroid-dependent type of aspirin asthma patients with Glucosidorum Tripterygii totorum].
Topics: Adult; Aspirin; Asthma; Corticosterone; Drugs, Chinese Herbal; Female; Humans; Immunosuppressive Age | 1994 |
Prostaglandin E2 and aspirin-induced asthma.
Topics: Aspirin; Asthma; Dinoprostone; Humans | 1995 |
Early and late onset asthmatic responses following lysine-aspirin inhalation in aspirin-sensitive asthmatic patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Br | 1995 |
The effect of aspirin desensitization on urinary leukotriene E4 concentrations in aspirin-sensitive asthma.
Topics: Adult; Aspirin; Asthma; Creatinine; Desensitization, Immunologic; Drug Hypersensitivity; Female; For | 1995 |
Severe asthma attacks precipitated by NSAIDs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Medical History Taki | 1995 |
Aspirin-induced asthma and artificial flavors.
Topics: Aspirin; Asthma; Flavoring Agents; Humans; Parabens; Salicylates; Toothpastes | 1994 |
[The diagnosis of aspirin-induced asthma by using a functional model].
Topics: Adult; Aspirin; Asthma; Computer Simulation; Diagnosis, Computer-Assisted; Humans; Models, Biologica | 1995 |
Autoimmune vasculitis preceding aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Autoantibodies; Female; Humans; Middle Aged; Vasculitis | 1995 |
Bisphosphonate-induced bronchoconstriction in aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Clodronic Acid; Etidronic Acid; Female; Humans; Middle Aged | 1994 |
Aspirin intolerance.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1994 |
[Liver function in patients with aspirin-induced bronchial asthma].
Topics: Aspirin; Asthma; Chronic Disease; Humans; Liver Diseases; Liver Function Tests; Severity of Illness | 1994 |
[The effect of disorders of thrombocyte functional activity on the microcirculatory status in the lungs and on external respiratory function in patients with aspirin-induced asthma].
Topics: Adult; Aspirin; Asthma; Blood Platelets; Capillaries; Convalescence; Humans; Lung; Male; Platelet Ag | 1993 |
[The late results of thrombocytapheresis in bronchial asthma patients].
Topics: Aspirin; Asthma; Blood Platelets; Calcium; Fenoterol; Humans; Platelet Aggregation; Plateletpheresis | 1993 |
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects.
Topics: Adolescent; Adult; Aspirin; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Leukotriene | 1993 |
[Intranasal provocation with lysine acetylsalicylic acid].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Drug Hyper | 1993 |
[Fundamental studies on the measurement of urinary leukotriene E4].
Topics: Aspirin; Asthma; Chromatography, High Pressure Liquid; Drug Hypersensitivity; Humans; Immunoenzyme T | 1994 |
Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects.
Topics: Administration, Oral; Adult; Airway Obstruction; Aspirin; Asthma; Bronchial Provocation Tests; Femal | 1994 |
Acetyl-CoA:lyso-platelet-activating factor acetyltransferase activity in neutrophils from asthmatic patients and normal subjects.
Topics: Acetyltransferases; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middl | 1993 |
[Bronchospasms caused by intravenous hydrocortisone sodium hemisuccinate (Solu-Cortef) in an aspirin-sensitive asthmatic patient].
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Hydrocortisone; Infusions, I | 1993 |
Aspirin-induced asthma.
Topics: Anesthesiology; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Contraindications; Cycloox | 1993 |
Mechanism of bronchospasm in aspirin-sensitive asthma.
Topics: Animals; Aspirin; Asthma; Bronchoconstriction; Drug Hypersensitivity; Guinea Pigs; Humans; Leukotrie | 1993 |
[Immunohistological study of eosinophilic infiltration of nasal polyps in aspirin-induced asthma].
Topics: Adult; Antibodies, Monoclonal; Aspirin; Asthma; Eosinophils; Female; Humans; Immunohistochemistry; M | 1993 |
Leukotrienes and aspirin induced asthma.
Topics: Aspirin; Asthma; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes | 1993 |
Dosimeter inhalation test with lysine acetylsalicylate for the detection of aspirin-induced asthma.
Topics: Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi | 1993 |
An analysis with sequence-specific oligonucleotide probes of the association between aspirin-induced asthma and antigens of the HLA system.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Base Sequence; Dose-Response Relationship, Drug; Drug Tole | 1993 |
[Nursing care of bronchogenic asthma].
Topics: Adult; Aspirin; Asthma; Female; Humans; Male; Posture; Stress, Psychological | 1993 |
[Bronchial provocation test in bronchial asthma].
Topics: Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cough; Humans; Methacholine | 1993 |
Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthma.
Topics: Adult; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Bronchoconstriction; Chymases; | 1993 |
Cu-Zn superoxide dismutase activities in platelets from stable bronchial asthmatic patients.
Topics: Adult; Aged; Aspirin; Asthma; Blood Platelets; Female; Humans; Male; Middle Aged; Superoxide Dismuta | 1993 |
Histamine metabolism in nasal polyps.
Topics: Amine Oxidase (Copper-Containing); Aspirin; Asthma; Bronchial Provocation Tests; Histamine; Histamin | 1993 |
Nasal secretions in response to acetylsalicylic acid.
Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Inflammation; Male; Middle Aged | 1993 |
The effect of aspirin on mononuclear cells in aspirin-sensitive asthmatics and control subjects.
Topics: Aspirin; Asthma; Humans; Hypersensitivity; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Su | 1993 |
[The viral and allergic origin of nasal polyposis].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Immunoglobulin E; Intradermal Tests; Nasal Polyps; R | 1993 |
The differential effect of aspirin on human platelet activation in aspirin-sensitive asthmatics and normal subjects.
Topics: Adenosine Triphosphate; Adult; Analysis of Variance; Arachidonic Acid; Aspirin; Asthma; Blood Platel | 1993 |
Ketorolac.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Apnea; Aspirin; Asthma; Drug Hypersensitivity; | 1993 |
Thresholds for aspirin intolerance.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1993 |
Autoimmune phenomena in bronchial asthma with special reference to aspirin intolerance.
Topics: Adolescent; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Antigen-An | 1995 |
Inflammatory cell populations in bronchial biopsies from aspirin-sensitive asthmatic subjects.
Topics: Administration, Inhalation; Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; | 1996 |
Incomplete aspirin desensitization in an aspirin-sensitive asthmatic.
Topics: Aspirin; Asthma; Bronchial Spasm; Desensitization, Immunologic; Drug Tolerance; Female; Humans; Midd | 1996 |
[The influence of misoprostol on post-aspirin bronchoconstriction in patients with aspirin sensitive asthma].
Topics: Adult; Aspirin; Asthma; Bronchoconstriction; Bronchodilator Agents; Female; Forced Expiratory Volume | 1995 |
Effect of endobronchial aspirin challenge on inflammatory cells in bronchial biopsy samples from aspirin-sensitive asthmatic subjects.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase | 1996 |
Menthol and aspirin-induced asthma.
Topics: Aspirin; Asthma; Female; Flavoring Agents; Humans; Male; Menthol | 1996 |
[Aspirin-induced asthma as an important type of bronchial asthma].
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzoates | 1995 |
[Recognizing drug-induced lung injury].
Topics: Aspirin; Asthma; Humans; Lung Diseases | 1995 |
Plasma zinc, copper and copper/zinc ratio in intrinsic asthma.
Topics: Aspirin; Asthma; Case-Control Studies; Copper; Humans; Zinc | 1996 |
Selenium status is decreased in patients with intrinsic asthma.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Aspirin; Asthma; Diet; Erythrocytes; Female; Food, Fo | 1996 |
Orbital complications of sinusitis in the aspirin triad syndrome.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Chronic Disease; Female; Humans; Male; Middle Aged; Orbita | 1996 |
Differential expression of platelet activation markers in aspirin-sensitive asthmatics and normal subjects.
Topics: Adult; Antigens, CD; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Cell Adhesion Molecules; Co | 1996 |
Complete resolution of airway hyperresponsiveness in aspirin-sensitive asthmatic patients.
Topics: Adult; Aspirin; Asthma; Bronchoconstriction; Female; Humans; Male; Middle Aged | 1996 |
Increased in vitro cysteinyl leukotriene release from blood leukocytes in patients with asthma, nasal polyps, and aspirin intolerance.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Leukocytes; Leukotrienes; Male; Middl | 1996 |
Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chest Pain; Eosinophilia; Esophagea | 1996 |
Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Outcome Assessm | 1996 |
Ketorolac-induced bronchospasm in an aspirin-intolerant patient.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Contraindications; | 1994 |
[Clinical evaluation of urinary leukotriene E4 levels in asymptomatic bronchial asthma].
Topics: Adult; Aspirin; Asthma; Humans; Leukotriene E4 | 1996 |
Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics.
Topics: Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Blood Proteins; Bronchi; Bronchoalveolar Lavage | 1996 |
[The in-vivo test of the inhibition of leukocyte natural migration with aspirin and analgin in the specific diagnosis of the asthmatic triad].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cell Migration Inhibition; Dipyrone | 1996 |
Autoimmune vasculitis and aortic stenosis in aspirin-induced asthma (AIA).
Topics: Aortic Valve Stenosis; Aspirin; Asthma; Autoimmune Diseases; Female; Humans; Middle Aged; Vasculitis | 1997 |
Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes.
Topics: Adult; Aged; Alleles; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Female; HLA-DP Antige | 1997 |
Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Case-Control Studies; Drug Hypersensitivity; Female; Humans; Leukotriene E4; Male; | 1997 |
[The oral provocation test by an alternative drug in patients with hypersensitivity to acetylsalicylic acid/non-steroidal anti-inflammatory agents].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Huma | 1996 |
Aspirin-induced asthma as a risk factor for asthma mortality.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Br | 1997 |
Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in aspirin-sensitive and non-aspirin-sensitive asthmatic airways.
Topics: Adult; Aspirin; Asthma; Bronchi; Cell Count; Drug Hypersensitivity; Epithelium; Female; Granulocyte- | 1997 |
Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Glutathione Transferase; Humans; Ma | 1997 |
[Progress on therapy and etiological study of bronchial asthma].
Topics: Administration, Inhalation; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 1997 |
Ketorlac-induced status asthmaticus after endoscopic sinus surgery in a patient with Samter's triad.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; F | 1997 |
Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma.
Topics: Aspirin; Asthma; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophils; Female; Glut | 1998 |
Too many COX (cyclo-oxygenase) spoil the broth: aspirin-sensitive asthma and 5-lypoxygenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Enzyme Activa | 1997 |
Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Cell Count; Eosinophils; F | 1997 |
Role of circulating immune complex in aspirin-sensitive asthma.
Topics: Adult; Aged; Antigen-Antibody Complex; Aspirin; Asthma; Case-Control Studies; Humans; Immunoglobulin | 1998 |
Anaphylaxis after prednisone.
Topics: Adolescent; Anaphylaxis; Aspirin; Asthma; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Pr | 1998 |
Urinary 9 alpha, 11 beta-PGF2 as a marker of mast cell activation in allergic and aspirin-intolerant asthma.
Topics: Antibodies; Antibody Specificity; Aspirin; Asthma; Biomarkers; Chromatography, High Pressure Liquid; | 1997 |
Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma.
Topics: Adult; Allergens; Aspirin; Asthma; Chi-Square Distribution; Female; Humans; Lysine; Male; Middle Age | 1998 |
Inhalation challenge in ASA-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstr | 1998 |
Immunohistochemical characterization of cellular infiltrate in nasal polyp from aspirin-sensitive asthmatic patients.
Topics: Adult; Aspirin; Asthma; Blood Proteins; CD3 Complex; Chymases; Eosinophil Granule Proteins; Humans; | 1998 |
Cyclo-oxygenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Humans; Prostaglandin-Endoperoxid | 1998 |
Cross sensitivities. Medication errors waiting to happen.
Topics: Analgesics, Non-Narcotic; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Interactions | 1999 |
Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient.
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Biopsy, Needle; Eosinophilia; Eosinophils; Follow-Up Studi | 1999 |
[Does idiopathic naso-sinusal polyposis exist in children?].
Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bacterial | 1999 |
Arachidonic acid metabolism in nasal tissue and peripheral blood cells in aspirin intolerant asthmatics.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Bronchial Provoca | 1999 |
The role of melatonin in pathogenesis of aspirin-sensitive asthma.
Topics: Adenosine Diphosphate; Adolescent; Aspirin; Asthma; Blood Platelets; Circadian Rhythm; Female; Human | 1999 |
Occurrence of allergic conditions in asthmatics with analgesic intolerance.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hyperse | 1999 |
Aspirin sensitivity: the role for aspirin challenge and desensitization in postmyocardial infarction patients.
Topics: Adult; Aged; Aspirin; Asthma; Desensitization, Immunologic; Diagnosis, Differential; Dose-Response R | 1999 |
Effects of sinus surgery on asthma in aspirin triad patients.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Airway Resistance; Aspirin; Asthma; Chro | 1999 |
Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Finland; Humans; Lung Disea | 1999 |
Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Finland; Humans; Lung Disea | 1999 |
Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Finland; Humans; Lung Disea | 1999 |
Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Finland; Humans; Lung Disea | 1999 |
Association of urinary leukotriene E4 excretion during aspirin challenges with severity of respiratory responses.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Leukotriene E4; Middle Aged | 1999 |
Antileukotriene therapy for the relief of sinus symptoms in aspirin triad disease.
Topics: Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Indoles; Leu | 1999 |
Amalgam allergy associated with exacerbation of aspirin-intolerant asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Dental Amalgam; Dipyrone; Female; Humans; Methach | 1999 |
NSAID-induced bronchospasm--a common and serious problem. A report from MEDSAFE, the New Zealand Medicines and Medical Devices Safety Authority.
Topics: Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Chroni | 1999 |
Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Ca | 2000 |
Outcome analysis of endoscopic sinus surgery for chronic sinusitis in patients having Samter's triad.
Topics: Adult; Age of Onset; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease | 2000 |
HLA-DRB1, -DQA1, and -DQB1 genotypes in patients with nasal polyposis.
Topics: Adult; Alleles; Aspirin; Asthma; DNA Probes; Drug Hypersensitivity; Genetic Linkage; Genotype; Haplo | 2000 |
Frequent paracetamol use and asthma in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2000 |
HLA patterns in patients with nasal polyposis.
Topics: Aspirin; Asthma; Drug Hypersensitivity; HLA Antigens; HLA-A Antigens; Humans; Nasal Polyps; Nose Neo | 2000 |
[Mild intermittent aspirin-induced asthma in a patient who became asymptomatic after removal of pet hamsters from home].
Topics: Adult; Allergens; Animals; Animals, Domestic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asth | 2000 |
5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States.
Topics: Alleles; Aspirin; Asthma; Genotype; Glutathione Transferase; Humans; Phenotype; Polymorphism, Geneti | 2000 |
Effects of pranlukast, a cysteinyl leukotriene antagonist, on bronchial responsiveness to methacholine in aspirin-intolerant asthmatics treated with corticosteroids.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aspirin; Asthma; Bronchial Hyperreactivity; Chromones; Drug To | 2000 |
Antileukotriene agents and aspirin-sensitive asthma: are we removing the second bassoonist or skating to where the puck is gonna be?
Topics: Aspirin; Asthma; Bronchial Spasm; Humans; Hydroxyurea; Leukotriene Antagonists; Therapeutic Equivale | 2000 |
Lack of effect of the 5-lipoxygenase inhibitor zileuton in blocking oral aspirin challenges in aspirin-sensitive asthmatics.
Topics: Administration, Oral; Aspirin; Asthma; Desensitization, Immunologic; Humans; Hydroxyurea; Leukotrien | 2000 |
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Fem | 2000 |
Drugs for pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2000 |
Is pre-menstrual asthma related to use of aspirin or non-steroidal anti-inflammatory drugs?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Humans; Male; Menstruation | 2000 |
Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma.
Topics: Adult; Alleles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; COS Cells; Eosino | 2000 |
The aspirin disease.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; C | 2000 |
Natural history of aspirin-induced asthma. AIANE Investigators. European Network on Aspirin-Induced Asthma.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Databases, | 2000 |
Thromboembolic prophylaxis with danaparoïd (Orgaran) in a high-thrombosis-risk pregnant woman with a history of heparin-induced thrombocytopenia (HIT) and Widal's disease.
Topics: Adult; Anticoagulants; Aspirin; Asthma; Cephalosporins; Chondroitin Sulfates; Dermatan Sulfate; Drug | 2000 |
Aspirin intolerance and related syndromes: a multidisciplinary approach. Proceedings of an international symposium. Rome, 11-13 November 1999.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Drug H | 2000 |
Intranasal challenge with aspirin in the diagnosis of aspirin intolerant asthma: evaluation of nasal response by acoustic rhinometry.
Topics: Administration, Intranasal; Adult; Aged; Aspirin; Asthma; Cyclooxygenase Inhibitors; Female; Humans; | 2000 |
[Family study of patients with aspirin intolerance and rhinosinusitis].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation T | 2000 |
Selective cyclo-oxygenase 2 inhibitor in patients with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fe | 2000 |
A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leucocytes precludes its value for aspirin sensitivity testing in asthma.
Topics: Adult; Aspirin; Asthma; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Female; HL-60 Cells; Hum | 2000 |
Montelukast is only partially effective in inhibiting aspirin responses in aspirin-sensitive asthmatics.
Topics: Acetates; Adult; Aged; Aspirin; Asthma; Bronchial Spasm; Cyclopropanes; Female; Forced Expiratory Vo | 2000 |
Tacholiquine inhalation and aspirin-induced asthma.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Diclofenac; Drug Hypersensitivity; E | 2001 |
Paracetamol and asthma.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; H | 2000 |
Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma.
Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Asthma; | 2001 |
Leukotriene C4 synthase polymorphism and aspirin-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Glutathione Transferase; Humans; Polymorph | 2001 |
[Antileukotrienes in the prevention of postoperative recurrence of nasal polyposis in ASA syndrome].
Topics: Acetates; Adult; Aged; Aspirin; Asthma; Cyclopropanes; Drug Hypersensitivity; Female; Humans; Leukot | 2000 |
Possible relevance of virus infection for development of analgesic idiosyncrasy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Herp | 2001 |
Serum interleukin-5 in aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Cysteine; Female; Humans; Interleukin-5; Leukotrienes; Male; Middle Aged | 2001 |
Effects of pranlukast on aspirin-induced bronchoconstriction: differences in chemical mediators between aspirin-intolerant and tolerant asthmatic patients.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchoconstriction; Chromones | 2001 |
Aspirin desensitization for chronic hyperplastic sinusitis, nasal polyposis, and asthma triad.
Topics: Adult; Aged; Aspirin; Asthma; Chronic Disease; Desensitization, Immunologic; Drug Hypersensitivity; | 2001 |
An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma.
Topics: Acetates; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asth | 2001 |
[Treatment of ASS-Associated Polyposis (ASSAP) with a cysteinyl leukotriene receptor antagonist - a prospective drug study on its antiinflammatory effects].
Topics: Acetates; Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Female; Humans; Leukotriene | 2001 |
Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cysteine; Cytochalasin B; Din | 2001 |
Airway hyperresponsiveness and pulmonary function in adult asthma.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Asthma; Bronchial Hyperreactivity; | 2001 |
Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Cyclooxygenase Inhibitors; Dinoprost; Fem | 2001 |
Montelukast for persistent asthma.
Topics: Acetates; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Humans; Leukotriene E4; Prednisone; | 2001 |
[The study of 18 cases of aspirin urticaria at dermatology of Yodogawa Christian Hospital--on the difference between aspirin asthma and aspirin urticaria].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Diagnosis, Differ | 2001 |
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients.
Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Chromone | 2002 |
Aspirin-sensitive versus non-aspirin-sensitive nasal polyp patients: analysis of leukotrienes/Fas and Fas-ligand expression.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Asthma; Eosinophils; fas Recepto | 2002 |
The role of COX-1 and COX-2 in asthma pathogenesis and its significance in the use of selective inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2002 |
[Fernand Widal syndrome: apropos of 2 cases].
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Cyclooxygenase Inhibitors; Female; Headache; Humans; Hyp | 1999 |
Clinical features and atopy profile in Turkish subjects with analgesic intolerance.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; | 2002 |
High levels of nitric oxide synthase activity are associated with nasal polyp tissue from aspirin-sensitive asthmatics.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Human | 2002 |
[Zafirlukast in treatment of nasal polyps in patients with aspirin intolerant bronchial asthma--preliminary report].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Indoles; Leukotriene Antagonists; Male; Nasal | 2002 |
Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Eosinophils; Female; Gene Frequency; Genotype; Glutathione T | 2002 |
Safety of a cyclooxygenase-2 inhibitor in patients with aspirin-sensitive asthma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Fe | 2002 |
How prevalent is aspirin induced asthma?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Leukotrienes; Prostaglandins | 2002 |
The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cohort Stu | 2002 |
[Tolerability of Asacard--controlled-release aspirin and aspirin-induced asthma].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cardiovascular Diseases; Delayed-Ac | 2002 |
International prostaglandin conference.
Topics: Arachidonic Acids; Aspirin; Asthma; Autacoids; Female; Humans; Male; Prostaglandins; Thromboxanes | 1979 |
Letter: Prostaglandins and aspirin-induced asthma.
Topics: Aspirin; Asthma; Humans; Prostaglandin Antagonists; Prostaglandins | 1976 |
Letter: Drug-induced asthma.
Topics: Aminopyrine; Aspirin; Asthma; Dipyrone; Drug Interactions; Female; Humans; Joint Diseases; Middle Ag | 1976 |
Nasal polyps, syncope, and asthma.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Nasal Polyps; Syncope; Syndrome | 1977 |
Life-threatening asthma, urticaria, and angiooedema after ketoprofen.
Topics: Adult; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Drug Synergism; Dyspnea; Humans; Ketoprof | 1978 |
[Drug-induced lung diseases].
Topics: Aspirin; Asthma; Bronchitis; Busulfan; Contraceptives, Oral, Hormonal; Dose-Response Relationship, D | 1979 |
Inhibition of idiosyncratic reactions to aspirin in asthmatic patients by clemastine.
Topics: Adult; Aspirin; Asthma; Clemastine; Female; Histamine Release; Humans; Male; Middle Aged; Peak Expir | 1979 |
Aspirin intolerance: unaltered susceptibility of platelet cyclo-oxygenase to inhibition by aspirin in vitro.
Topics: Adult; Aged; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Dru | 1978 |
[Aspirin-induced asthma--detection by inhalation challenge with sulpyrine (author's transl)].
Topics: Adult; Aminopyrine; Animals; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dipyrone; Female; Guinea Pi | 1979 |
Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Female; Humans; Indomethacin; | 1979 |
[Diagnostic problems in drug hypersensitivity].
Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H | 1977 |
[Drug-induced bronchospasm (author's transl)].
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; H | 1978 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
[Defect of the neuromuscular transmission in bronchial asthma due to acetylsalicylic acid intolerance].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Motor Endplate; Ne | 1979 |
[Acute diarrhea caused by penicillin; bronchial asthma by aspirin; and dental hypoplasia induced by antiepileptic drugs].
Topics: Adult; Anticonvulsants; Aspirin; Asthma; Colitis; Dental Enamel Hypoplasia; Female; Humans; Odontoge | 1979 |
Aspirin idiosyncrasy.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Male; Middle Aged; Nasal Polyps; Rhinitis | 1979 |
Asthma and nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Humans; Phenylbutazone | 1979 |
Prostaglandins and aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Depression, Chemical; Epoprostenol; Humans; Prostaglandins; Prostaglandins E; Throm | 1978 |
Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naproxen.
Topics: Adult; Aspirin; Asthma; Cyclooxygenase Inhibitors; Diclofenac; Drug Hypersensitivity; Female; Humans | 1977 |
Aspirin intolerance, asthma, prostaglandins, and cromolyn sodium.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Child; Child, Preschool; Cromolyn Sodium; Humans; Infant; | 1977 |
Aspects of bronchial reactivity to prostaglandins and aspirin in asthmatic patients.
Topics: Adolescent; Adult; Aerosols; Aminophylline; Aspirin; Asthma; Bronchi; Cromolyn Sodium; Drug Hypersen | 1977 |
Clinical patterns of hypersensitivity to nonsteroidal anti-inflammatory drugs and their pathogenesis.
Topics: Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents; Aspirin; Asthma; Cyclooxygenase Inhib | 1977 |
Oral acetylsalicylic acid (aspirin) challenge in asthmatic children.
Topics: Adolescent; Aspirin; Asthma; Child; Female; Humans; Male; Peak Expiratory Flow Rate | 1979 |
Nasal polypectomy in patients with asthma and sensitivity to aspirin.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; Hu | 1979 |
[Asthma in children caused by aspirin. Report of 3 cases].
Topics: Aspirin; Asthma; Child; Drug Hypersensitivity; Female; Humans | 1979 |
[Bronchial asthma caused by food preservatives, food coloring agents and aspirin in children].
Topics: Adolescent; Aspirin; Asthma; Child; Child, Preschool; Female; Food Coloring Agents; Food Preservativ | 1979 |
[Deforming, recurrent nasal polyposis in the adult].
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Child; Cystic Fibrosis; Drug Hypersensitivity; Huma | 1979 |
Hypersensitivity to nonsteroidal antiinflammatory drugs: indications and methods for oral challenges.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Human | 1979 |
Evaluation of aspirin and tartrazine idiosyncrasy.
Topics: Aspirin; Asthma; Azo Compounds; Bronchial Provocation Tests; Drug Hypersensitivity; Humans; Tartrazi | 1979 |
Aspirin and concomitant idiosyncrasies in adult asthmatic patients.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aspirin; Asthma; Azo Compounds; Drug H | 1979 |
[Study of the characteristics of pathogenesis and clinical course of asthmatic triad].
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Diagnosis, Differential; Drug Hypersensitivity; Female; | 1979 |
[Anti-inflammatory agents and aspirin-induced asthma].
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Dose-Response Relationship, Drug; Drug Hypersensitivity; | 1979 |
Triamcinolone aerosol. Treatment of aspirin-hypersensitive asthmatic patients.
Topics: Aerosols; Aspirin; Asthma; Drug Hypersensitivity; Humans; Lung; Prednisone; Triamcinolone Acetonide | 1977 |
Measurement of nucleotide pools in platelets using high pressure liquid chromatography.
Topics: Aspirin; Asthma; Blood Platelets; Chromatography, High Pressure Liquid; Nucleotides | 1977 |
Indomethacin-induced asthma in aspirin-sensitive patients.
Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin | 1977 |
[Indomethacin-induced asthma (author's transl)].
Topics: Adult; Aspirin; Asthma; Female; Humans; Indomethacin; Male; Middle Aged | 1977 |
[Coloring agents, preservatives and drugs. The aspirin disease once more].
Topics: Adult; Aspirin; Asthma; Coloring Agents; Female; Food Coloring Agents; Food Preservatives; Humans; M | 1978 |
Analgesics, asthma, and prostaglandins.
Topics: Aspirin; Asthma; Humans; Prostaglandins | 1978 |
Adverse bronchial reactions to intravenous hydrocortisone in two aspirin-sensitive asthmatic patients.
Topics: Adult; Aged; Airway Obstruction; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Hydrocortis | 1978 |
Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors.
Topics: Animals; Ascaris; Aspirin; Asthma; Dogs; Hypersensitivity; Hypoxia; Indomethacin; Lung; Oxygen; Pros | 1978 |
Halothane for status asthmaticus in the intensive care unit--a case report.
Topics: Adult; Aspirin; Asthma; Halothane; Humans; Intensive Care Units; Male | 1978 |
[Experimental investigation on the pathogenesis of aspirin-induced asthma--the effect of aspirin on the relaxation of guinea pig tracheal tissues with various bronchodilators (author's transl)].
Topics: Animals; Aspirin; Asthma; Bronchodilator Agents; Guinea Pigs; In Vitro Techniques; Male; Muscle Rela | 1978 |
Aspirin-improved ASA triad.
Topics: Aspirin; Asthma; Female; Humans; Middle Aged; Nasal Polyps; Sinusitis | 1978 |
Risk of naproxen in patients with aspirin sensitivity.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Naproxen | 1978 |
[Prostaglandins and lung function. III. Effect of prostaglandin E-2 on the bronchial tree in asthma].
Topics: Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Humans; Prostaglandins E; Respiratory Function Test | 1978 |
Cross-reactivity between aspirin and ibuprofen in an asthmatic--a case report.
Topics: Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Humans; Ibuprofen; Male; Middle Aged | 1978 |
Asthma and nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Humans | 1978 |
Food sensitivity reported by patients with asthma and hay fever. A relationship between food sensitivity and birch pollen-allergy and between food sensitivity and acetylsalicylic acid intolerance.
Topics: Adolescent; Adult; Aged; Allergens; Aspirin; Asthma; Child; Female; Food Hypersensitivity; Humans; M | 1978 |
Histamine and acetaminophen--a reader's "untoward" reaction.
Topics: Acetaminophen; Aspirin; Asthma; Histamine; Humans | 1978 |
Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors.
Topics: Aspirin; Asthma; Fenoprofen; Humans; Indomethacin; Male; Mefenamic Acid; Middle Aged | 1978 |
Acetylsalicyclic asthma and migraine - a defect in serotonin (5-HT) uptake in platelets.
Topics: Aspirin; Asthma; Blood Platelets; Humans; Migraine Disorders; Serotonin | 1978 |
Aspirin, prostaglandins and bronchial asthma [proceedings].
Topics: Aspirin; Asthma; Bronchi; Humans; Prostaglandins | 1978 |
Inhibition of gill cilial activity and of Proteus vulgaris motility as tests for aspirin idiosyncrasy.
Topics: Animals; Aspirin; Asthma; Bivalvia; Cilia; Drug Hypersensitivity; Humans; Proteus vulgaris | 1976 |
Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations.
Topics: Adolescent; Adult; Aspirin; Asthma; Constriction, Pathologic; Dextropropoxyphene; Drug Hypersensitiv | 1976 |
Inhibitory effects of various drugs on dual asthmatic responses in wheat flour-sensitive subjects.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Cromolyn Sodium; Diethylcarbamazine; Flour; Forced | 1976 |
Nasal polyps and bronchial asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Hypersensitivity; Nasal Mucosa; Nasal Polyps | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Nasal polyps in asthma and rhinitis. A review of 6,037 patients.
Topics: Adolescent; Adult; Aging; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Female; H | 1977 |
Aspirin intolerance in asthmatic patients: case histories.
Topics: Adult; Aspirin; Asthma; Female; Humans; Rhinitis; Sinusitis | 1977 |
[Aspirin-induced asthma].
Topics: Adult; Aged; Anaphylaxis; Aspirin; Asthma; Female; Humans | 1977 |
Bronchial response to inhaled prostaglandin F2alpha in patients with common or aspirin-sensitive asthma.
Topics: Aerosols; Airway Resistance; Aspirin; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Tolera | 1977 |
Participation of prostaglandins in pathogenesis of aspirin-sensitive asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Prostaglandins | 1977 |
Plasma complement changes during bronchospasm provoked in asthmatic patients.
Topics: Aerosols; Antigens; Aspirin; Asthma; Bronchial Spasm; Complement C1; Complement C3; Complement C4; C | 1977 |
Aspirin-sensitive asthma: the effect of aspirin on the release of prostaglandins from nasal polyps.
Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Asthma; Female; Humans; In Vitro Techniques; Ma | 1977 |
[Experimental investigation on the pathogenesis of aspirin-induced asthma--the effects of aspirin on the contraction of guinea-pig tracheal tissues with various bronchoconstrictors (author's transl)].
Topics: Acetylcholine; Animals; Aspirin; Asthma; Bradykinin; Dose-Response Relationship, Drug; Drug Synergis | 1977 |
Bronchial reactivity to prostaglandins F2alpha, E2, and histamine in different types of asthma.
Topics: Adult; Aerosols; Aged; Aspirin; Asthma; Bronchi; Dose-Response Relationship, Drug; Female; Histamine | 1977 |
[Classification of bronchial asthma].
Topics: Aspirin; Asthma; Bronchitis; Drug Tolerance; Humans; Hypersensitivity, Immediate; Personality; Physi | 1977 |
Nasal polyps, nasal polypectomy, asthma, and aspirin sensitivity. Their association in 445 cases of nasal polyps.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; | 1977 |
Intolerance to aspirin: clinical and immunological studies.
Topics: Adolescent; Adult; Aspirin; Asthma; Child; DNA; Drug Hypersensitivity; Female; Humans; Lysine; Male; | 1976 |
Complement components and IgE in patients with asthma and aspirin idiosyncrasy.
Topics: Aspirin; Asthma; Complement C3; Complement C4; Drug Hypersensitivity; Female; Humans; Immunoglobulin | 1976 |
[Aspirin disease. Bronchial asthma and rhinitis caused by analgesics, food coloring agents and food preservatives].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Food Coloring Agents; Food Preservatives; Hum | 1976 |
Acute respiratory failure secondary to indomethacin in an aspirin-intolerant asthmatic patient.
Topics: Acute Disease; Aspirin; Asthma; Drug Hypersensitivity; Humans; Indomethacin; Male; Middle Aged; Resp | 1976 |
Oral aspirin challenges in asthmatic patients: a study of plasma histamine.
Topics: Administration, Oral; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Expiratory | 1976 |
[Asthma- -aspirin- -ascaris].
Topics: Ascaris; Aspirin; Asthma; Feces; Humans; Male; Middle Aged; Nasal Polyps | 1976 |
Aspirin idiosyncrasy in patients admitted for nasal polypectomy.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Lung Volume Measurements; Male; Middle Aged; | 1976 |
Nasal polypi.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps | 1976 |
[Asthmatic patients with hypersensitivity for aspirin, benzoic acid and tartrazine].
Topics: Aspirin; Asthma; Azo Compounds; Benzoates; Drug Hypersensitivity; Humans; Tartrazine | 1976 |
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H | 1975 |
Aspirin allergy: a clinical study.
Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Fema | 1975 |
Intrinsic asthma associated with diabetes mellitus; abnormal vascular response and glucose tolerance tests.
Topics: Aspirin; Asthma; Blood Coagulation Tests; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Diabet | 1975 |
Letter: Inhibition of prostaglandin biosynthesis by analgesics in relation to asthma.
Topics: Acetaminophen; Aspirin; Asthma; Depression, Chemical; Humans; Prostaglandins; Spirometry | 1975 |
Provoking factors in bronchial asthma.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchitis; Child; Child, Preschool; Drug Hypersensitivity | 1975 |
Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine.
Topics: Angioedema; Aspirin; Asthma; Azo Compounds; Benzenesulfonates; Bronchial Spasm; Cross Reactions; Dru | 1975 |
Prostaglandin levels in blood plasma during asthmatic attacks in patients with aspirin idiosyncrasy.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Prostaglandins; Pr | 1975 |
Proceedings: Asthmatic patients with hypersensitivity to aspirin, benzoic acid and tartrazine.
Topics: Adult; Aspirin; Asthma; Azo Compounds; Benzenesulfonates; Benzoates; Coloring Agents; Drug Hypersens | 1975 |
Intolerance to aspirin.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Rhinitis | 1975 |
[Advances in pneumonology. Aspirin-induced asthma].
Topics: Adult; Age Factors; Aspirin; Asthma; Depression, Chemical; Drug Hypersensitivity; Humans; Indomethac | 1975 |
Diabetes mellitus and insulin in an aspirin sensitive asthmatic.
Topics: Aspirin; Asthma; Azo Compounds; Benzenesulfonates; Coloring Agents; Diabetes Complications; Diabetes | 1976 |
The diagnosis of aspirin idiosyncrasy by analgesic challenge.
Topics: Acetaminophen; Adolescent; Adult; Aged; Airway Obstruction; Aspirin; Asthma; Drug Hypersensitivity; | 1976 |
Increased excretion of leukotriene E4 during aspirin-induced asthma.
Topics: Aspirin; Asthma; Creatinine; Dose-Response Relationship, Drug; Humans; Leukotriene E4; SRS-A | 1992 |
Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics.
Topics: Adult; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotrie | 1992 |
Urinary leukotriene E4 in bronchial asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Drug Hypersensitivit | 1992 |
Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge.
Topics: Administration, Oral; Adult; Arachidonic Acid; Aspirin; Asthma; Bronchial Spasm; Calcimycin; Eicosan | 1992 |
[A case of aspirin-induced asthma due to ketoprofen adhesive agent].
Topics: Adult; Aspirin; Asthma; Female; Humans; Ketoprofen; Respiration, Artificial; Skin Absorption | 1992 |
Platelet kinetics in asthmatic patients with and without aspirin intolerance.
Topics: Adult; Aspirin; Asthma; Blood Platelets; Cell Survival; Drug Tolerance; Female; Humans; Indium Radio | 1992 |
[Current aspects of analgetics-induced asthma].
Topics: Algorithms; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; | 1992 |
Prognostic factors, outcomes and staging in ethmoid sinus surgery.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Ethmoid Sinus; Ethmoid S | 1992 |
Incidence of medico-surgical treatment for nasal polyps on the development of associated asthma.
Topics: Aspirin; Asthma; Bronchial Hyperreactivity; Drug Hypersensitivity; Ethmoid Sinus; Female; Humans; In | 1992 |
[A case of asthma relieved by aspirin--the first case in Japan and investigation of its mechanism].
Topics: Aspirin; Asthma; Cyclooxygenase Inhibitors; Humans; Japan; Lung Volume Measurements; Male; Middle Ag | 1992 |
[Inhibitory effect of amlexanox on asthmatic attacks in an aspirin sensitive asthmatic].
Topics: Adolescent; Aminopyridines; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; SRS-A | 1992 |
Flurbiprofen (Ansaid) cross-sensitivity in an aspirin-sensitive asthmatic patient.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Flurbiprofen; Humans; Male; Middle Aged | 1992 |
Altered distribution of IgG subclasses in aspirin-induced asthma: high IgG4, low IgG1.
Topics: Aspirin; Asthma; Humans; Immunoglobulin G; Tissue Distribution | 1992 |
In vitro study of platelets and circulating mononuclear cells of subjects presenting an intolerance to aspirin.
Topics: Aged; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Female; Humans; In | 1992 |
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma.
Topics: Adult; Aged; Aspirin; Asthma; Basophils; Cytochalasin B; Dexamethasone; Female; Histamine Release; H | 1990 |
Tryptase and histamine release during aspirin-induced respiratory reactions.
Topics: Administration, Oral; Adult; Aspirin; Asthma; Forced Expiratory Volume; Histamine; Histamine Release | 1991 |
Asthma relieved by aspirin: clinical studies, platelet function, and arachidonate metabolism.
Topics: Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Female; Humans; Middl | 1992 |
Asthma and HLA system.
Topics: Alleles; Aspirin; Asthma; Base Sequence; Disease Susceptibility; Genes, Dominant; Genetic Markers; G | 1991 |
Mediator release in aspirin-induced reactions.
Topics: Anaphylaxis; Arachidonic Acid; Aspirin; Asthma; Drug Hypersensitivity; Humans; Leukotrienes | 1991 |
[Mortality from asthma].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Asthma; Child; Child, Preschool; F | 1991 |
Sodium salicylate sensitivity in an asthmatic patient with aspirin sensitivity.
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Cross Reactions; Drug Hypersensitivity; Female; Humans | 1991 |
[A case of hypereosinophilic syndrome followed by bronchial asthma, intraventricular thrombus, and duodenitis].
Topics: Adult; Aspirin; Asthma; Duodenitis; Eosinophilia; Heart Diseases; Humans; Male; Myocarditis; Prednis | 1991 |
[The results of the dynamic observation of bronchial hyperreactivity in risk-group subjects and in bronchial asthma patients. Some corrective procedures].
Topics: Acetylcholine; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cold Tempera | 1991 |
[Characteristics of functional activity of thrombocytes in patients with "aspirin" bronchial asthma].
Topics: Aspirin; Asthma; Epoprostenol; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Count; Pl | 1991 |
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans; | 1991 |
Aspirin-induced asthma and bronchial hyperresponsiveness.
Topics: Adolescent; Adult; Airway Resistance; Angioedema; Aspirin; Asthma; Bronchial Hyperreactivity; Bronch | 1991 |
Release of peptide leukotrienes into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatics.
Topics: Aspirin; Asthma; Double-Blind Method; Drug Hypersensitivity; Humans; Instillation, Drug; Leukotriene | 1991 |
[Neutrophil chemotactic activity after administration of aspirin during aspirin tolerance in patients with asthma and aspirin hypersensitivity].
Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemotaxis, Leukocyt | 1991 |
[Alpha 1-antitrypsin and its phenotype in patients with asthma and aspirin hypersensitivity].
Topics: Adult; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Aspirin; Asthma; Bronchi; Bronchial Prov | 1991 |
[Effect of aspirin on FMLP (formyl-meth-leu-phe)-stimulated leukocytes in patients with asthma and hypersensitivity to aspirin].
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Humans; | 1991 |
Cyclosporin for a severe case of aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Cyclosporins; Female; Humans | 1991 |
Delayed generation of thrombin in clotting blood of atopic patients with hayfever and asthma.
Topics: Aspirin; Asthma; Bleeding Time; Fibrinopeptide A; Hemostasis; Humans; Rhinitis, Allergic, Seasonal; | 1991 |
Inhalation and nasal challenge in the diagnosis of aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; | 1991 |
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance; | 1991 |
[Practical problems of the treatment of asthma].
Topics: Adult; Aspirin; Asthma; Bronchodilator Agents; Child; Congresses as Topic; Drug Hypersensitivity; Gl | 1990 |
[The clinico-immunological and allergological characteristics of aspirin-induced asthma].
Topics: Adolescent; Adult; Allergens; Aspirin; Asthma; Drug Tolerance; Female; Humans; Hypersensitivity, Imm | 1991 |
[Asthma and hypersensitivity for acetylsalicylic acid].
Topics: Aspirin; Asthma; Humans; Naproxen | 1991 |
Selenium status in relation to reduced glutathione peroxidase activity in aspirin-sensitive asthma.
Topics: Adult; Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Female; Glutathione Peroxidase; Huma | 1991 |
[Relief of asthma with acetylsalicylic acid].
Topics: Aspirin; Asthma; Humans | 1991 |
Plasmapheresis in a patient with severe asthma associated with auto-antibodies to platelets.
Topics: Adult; Aspirin; Asthma; Autoantibodies; Blood Platelets; Drug Hypersensitivity; Humans; Immunoglobul | 1990 |
[Asthma improved with acetylsalicylic acid].
Topics: Adult; Aspirin; Asthma; Drug Evaluation; Female; Humans; Single-Blind Method | 1990 |
Aspirin-sensitive asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inh | 1990 |
Aspirin--relieved asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Drug Tolerance; Humans; Models, Biological; Pr | 1990 |
In vitro tests for the diagnosis of aspirin-sensitive asthma.
Topics: Adult; Aged; Aspirin; Asthma; beta-Thromboglobulin; Blood Platelets; Dinoprost; Dinoprostone; Drug T | 1990 |
The abnormal in vitro response to aspirin of platelets from aspirin-sensitive asthmatics is inhibited after inhalation of nedocromil sodium but not of sodium cromoglycate.
Topics: Administration, Inhalation; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; B | 1990 |
[Severe bronchial reaction induced by hydrocortisone sodium succinate in an aspirin-sensitive asthmatic patient].
Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Hydrocortisone | 1990 |
[Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma].
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchi; Bronchial Spasm; Bronchoconstrictor Agents; Bronc | 1990 |
Surgery for sinusitis and aspirin triad.
Topics: Adolescent; Adult; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Female; Follow-Up Studie | 1990 |
Nasal polyposis as a risk factor for hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Asthma; C | 1990 |
[Infantile asthma, IgA deficiency and acetylsalicylic acid intolerance. A clinical case and its evolution].
Topics: Aspirin; Asthma; Child, Preschool; Drug Hypersensitivity; Humans; IgA Deficiency; Immunoglobulin A, | 1990 |
Long-term effects of aspirin desensitization--treatment for aspirin-sensitive rhinosinusitis-asthma.
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Combined Modality Therapy; Desensitization, Immunol | 1990 |
[Fernand Widal syndrome and sulfite intolerance. Therapeutic problems in general and ORL problems in particular].
Topics: Aspirin; Asthma; Cross-Sectional Studies; Drug Hypersensitivity; France; Humans; Nasal Polyps; Prese | 1990 |
Bronchial provocation testing of sodium iso-nonanoyl oxybenzene sulphonate.
Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Benzenesulfonates; Bronchi; Bronchial Provocatio | 1990 |
Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin.
Topics: Adolescent; Adult; Aspirin; Asthma; Child; Drug Tolerance; Eosinophilia; Female; Humans; Male; Middl | 1990 |
Abnormal platelet hydrogen peroxide metabolism in aspirin hypersensitivity.
Topics: Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Glutathione Peroxidase; Humans; Hydrogen Pe | 1990 |
[Is sodium salicylate suitable as a protective agent in the analgesic-induced asthma syndrome?].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Forced Exp | 1990 |
Comparison of bronchial and per oral provocation with aspirin in aspirin-sensitive asthmatics.
Topics: Administration, Inhalation; Administration, Oral; Aspirin; Asthma; Bronchial Provocation Tests; Drug | 1990 |
[Changes in the functional and biochemical characteristics of the thrombocytes in the side effects of nonsteroidal anti-inflammatory preparations].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Platelets; Drug Hypersensitivity; Dr | 1990 |
[Clinical and pathogenetic aspects of aspirin intolerance].
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Complement Activation; Drug Eruptions; Histami | 1986 |
Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin.
Topics: Adult; Aspirin; Asthma; Dinoprostone; Drug Hypersensitivity; Female; Forced Expiratory Volume; Hista | 1988 |
[The changes in plasma histamine levels after a sulpyrin inhalation test in asthmatic patients].
Topics: Adult; Aminopyrine; Aspirin; Asthma; Bronchial Provocation Tests; Dipyrone; Female; Histamine; Hista | 1989 |
[Platelet aggregation in asthma].
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchial Provocation T | 1989 |
Etiology of nasal polyps associated with aspirin-sensitive asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Cytoplasmic Granules; Drug Hypersensitivity; E | 1989 |
On the mechanism of aspirin asthma.
Topics: Aspirin; Asthma; Humans; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Lysine | 1989 |
[NARES syndrome. A developing link in the Fernand-Widal triad].
Topics: Adult; Aspirin; Asthma; Autonomic Nervous System Diseases; Eosinophilia; Female; Humans; Male; Middl | 1989 |
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotriene B4; Male | 1989 |
Nedocromil sodium inhibition of IgE-mediated activation of human mononuclear phagocytes and platelets from asthmatics.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Platelets; Cell Survival; C | 1989 |
[The late results of aspirin treatment in patients with aspirin-induced bronchial asthma].
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Dose-Response Relationship, Drug; Female; Foll | 1989 |
Oral provocation tests with aspirin and food additives in asthmatic patients.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Female | 1989 |
[Hemosorption in the treatment of aspirin-induced bronchial asthma].
Topics: Adult; Aspirin; Asthma; Bronchi; Desensitization, Immunologic; Drug Hypersensitivity; Female; Hemope | 1989 |
Immunohistological characteristics of nasal polyps. A comparison with healthy mucosa and chronic sinusitis.
Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Aspirin; Asthma; Complement System Proteins; Drug | 1989 |
Aspirin-intolerance as a precipitating factor of life-threatening attacks of asthma requiring mechanical ventilation.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensiti | 1989 |
Glucocorticosteroids attenuate aspirin-precipitated adverse reactions in aspirin-intolerant patients with asthma.
Topics: Adult; Aspirin; Asthma; Beclomethasone; Double-Blind Method; Drug Hypersensitivity; Female; Forced E | 1989 |
Recurrence of nasal polyps after surgical treatment.
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Drug Hypersensitivity; Ethmoid Sinus; Follow-Up Studies; H | 1989 |
[Ibuprofen triggered asthma attack in a patient with known aspirin hypersensitivity].
Topics: Aged; Aspirin; Asthma; Drug Hypersensitivity; Humans; Ibuprofen; Male | 1989 |
Reduced production of oxygen-free radicals of platelets in aspirin-induced-asthma.
Topics: Adult; Aspirin; Asthma; Blood Platelets; Female; Free Radicals; Humans; Male; Methylprednisolone; Ox | 1989 |
An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Arachidonate 12-Lipoxygenase; Arachidonic Acids; | 1988 |
Crossed tolerance to pyrazolines, mephenamic acid, and glafenine in A. S. A.-triad patients desensitized to aspirin.
Topics: Aspirin; Asthma; Cross Reactions; Desensitization, Immunologic; Drug Tolerance; Female; Glafenine; H | 1985 |
Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria.
Topics: Adult; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Food Additives; Glafenine; Humans; Middle | 1985 |
New therapeutic approaches in asthma.
Topics: Adrenergic beta-Agonists; Aerosols; Airway Obstruction; Aspirin; Asthma; Bronchi; Bronchodilator Age | 1986 |
[Occurrence of drug reactions].
Topics: Acetaminophen; Adult; Anaphylaxis; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Emergencies; | 1986 |
Two cases of aspirin-intolerant asthma whose leukocytes demonstrated hypersensitivity to sulpyrin.
Topics: Adolescent; Aminopyrine; Aspirin; Asthma; Bronchial Provocation Tests; Dipyrone; Drug Hypersensitivi | 1989 |
Pseudo-allergic reactions--PAR.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Reactions; Aspirin; Asthma; Blood Platelet | 1987 |
Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; | 1987 |
Platelet activation by IgE and aspirin.
Topics: Animals; Aspirin; Asthma; Blood Platelets; Cytotoxicity, Immunologic; Humans; Hypersensitivity; Immu | 1987 |
New functions for platelets and their pathological implications.
Topics: Animals; Aspirin; Asthma; Blood Platelets; Cytotoxicity, Immunologic; Drug Hypersensitivity; Glycopr | 1985 |
[Bronchial hyperresponsiveness in aspirin induced asthma].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Dinoprost; Female; Histamine; Humans; Mal | 1988 |
Lowered glutathione-peroxidase activity in asthmatic patients with food and aspirin intolerance.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Dr | 1986 |
[Effect of aspirin on exercise-induced bronchospasm].
Topics: Adolescent; Aspirin; Asthma; Asthma, Exercise-Induced; Child; Cromolyn Sodium; Female; Heart Rate; H | 1986 |
Eicosanoids and aspirin-sensitive asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Humans; Prostaglandin-Endoper | 1987 |
Aspirin-induced asthma as a viral disease.
Topics: Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Models, Biological; Prostaglandin- | 1988 |
[Blood platelets and asthma caused by aspirin].
Topics: Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Desensitization, Immunologic; Drug Hype | 1987 |
[Tracheal instillation of arachidonic acid as an asthma model in guinea pigs--preliminary results of the effect of inhibitors of arachidonic acid metabolism].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Cyclooxygenase Inhibitors; Disease Mo | 1988 |
[Etiology and treatment of intractable asthma--non-immunological features].
Topics: Adult; Animals; Aspirin; Asthma; Benzoquinones; Drug Hypersensitivity; Female; Guinea Pigs; Humans; | 1988 |
[A new method of diagnosis of aspirin-induced asthma by inhalation test with water-soluble aspirin (aspirin DL-lysine, Venopirin].
Topics: Adult; Aerosols; Aspirin; Asthma; Bronchial Provocation Tests; Female; Humans; Lysine; Male | 1988 |
Specific immunotherapy with a standardized Dermatophagoides pteronyssinus extract. II. Prediction of efficacy of immunotherapy.
Topics: Adolescent; Adult; Aged; Allergens; Animals; Antigens, Dermatophagoides; Aspirin; Asthma; Child; Chi | 1988 |
[Mechanisms of aspirin desensitization in patients with aspirin-induced asthma].
Topics: Adolescent; Aspirin; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Desensitization, | 1988 |
[Desensitization in intolerance to acetylsalicylic acid].
Topics: Adult; Angioedema; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Female; Hum | 1988 |
[Aspirin-induced asthma in children].
Topics: Acute Disease; Adolescent; Anaphylaxis; Aspirin; Asthma; Child; Drug Hypersensitivity; Drug Toleranc | 1988 |
[A clinical analysis of 200 cases of aspirin-induced asthma].
Topics: Adolescent; Adult; Aerosols; Aged; Aspirin; Asthma; Beclomethasone; Child; Female; Humans; Male; Mid | 1988 |
Aspirin-induced asthma in a patient with asthma previously improved by non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Female; Human | 1988 |
[Allergic problems in relation to antipyretic analgesic treatment in pediatrics].
Topics: Adolescent; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Female; Humans; Infant; Male; Urti | 1988 |
[Bronchial asthma with aspirin hypersensitivity?].
Topics: Aspirin; Asthma; Bronchi; Bronchodilator Agents; Drug Hypersensitivity; Humans | 1988 |
[Chemotactic activity of serum neutrophils during aspirin-induced bronchial spasm].
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chemotaxis, Leukocyte; Drug Hy | 1987 |
Pharmacological attempts to modulate leukotriene synthesis in aspirin-induced asthma.
Topics: Aspirin; Asthma; Epoprostenol; Forced Expiratory Volume; Humans; SRS-A | 1987 |
First complete description of the aspirin idiosyncrasy-asthma-nasal polyposis syndrome (plus urticaria)--1922 (with a note on aspirin desensitization). By F. Widal, P. Abrami, J. Lermoyez.
Topics: Anaphylaxis; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; History, 20th Cen | 1987 |
Plasma histamine after methacholine, allergen, and aspirin challenges.
Topics: Adult; Antigens; Aspirin; Asthma; Female; Histamine; Humans; Hypersensitivity, Immediate; Lignans; M | 1987 |
Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study.
Topics: Adult; Aged; Albuterol; Aspirin; Asthma; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Drug Comb | 1988 |
Aspirin sensitivity and recurrent polyposis.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Recurrence | 1988 |
[Clinical picture, diagnosis and treatment of patients with bronchial asthma and intolerance for acetylsalicylic acid].
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Combined Modality Therapy; Desensitization, Immunologi | 1988 |
[Therapeutic programs in bronchial asthma].
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aspirin; Asthma; Bronchodilator Agents; Combined Mo | 1987 |
Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria.
Topics: Aspirin; Asthma; Butyrylcholinesterase; Cholinesterases; Esterases; Humans; Urticaria Pigmentosa | 1987 |
[Intolerance to metabisulfites in asthma induced by aspirin].
Topics: Administration, Oral; Aspirin; Asthma; Female; Humans; Immunoglobulin G; Male; Middle Aged; Skin Tes | 1987 |
[Asthma caused by aspirin].
Topics: Aspirin; Asthma; Humans | 1987 |
[Reactions to metabisulfites in aspirin-induced asthma].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Food Additives; Humans; Male; Middle Aged; Sp | 1987 |
Association of aspirin-sensitive asthma with HLA-DQw2.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Histocompatibility Antigens Class II; HLA Antigens; HLA-DQ A | 1986 |
Aspirin-intolerance syndrome. Report of a case.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Facial Pain; Humans; Male; Nasal Polyps; Syndrome | 1986 |
Aspirin-induced asthma and nasal polyps.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Eosinophilia; Female; Humans; Immunoglobulin E; Male; | 1986 |
Primary thrombocythaemia in childhood: symptomatic episodes and their relationship to thromboxane A2, 6-keto-PGE1 and 12-hydroxy-eicosatetraenoic acid production: a case report.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Alprostadil; Arachidonate | 1987 |
Evidence of PAF release and platelet activation in analgesics-asthma-syndrome.
Topics: Aspirin; Asthma; Blood Platelets; Collagen; Drug Synergism; Female; Humans; Male; Platelet Activatin | 1987 |
Pyrazolones and analgesic asthma syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Child; Dipyrone; Female; Humans; Im | 1986 |
Histopathology and immunofluorescent immunoglobulins in asthmatics with aspirin idiosyncrasy.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Fluorescent Antibody Technique; Humans; Immun | 1987 |
[A study of the clinical feature of 29 cases with aspirin-induced asthma].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; | 1986 |
[Characteristics of the pathogenesis and diagnosis of aspirin-induced bronchial asthma].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged | 1986 |
[Aspirin-induced asthma].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1986 |
Fibrinolysis, blood coagulation, and platelet function during aspirin-induced bronchoconstriction in aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Blood Coagulation; Blood Platelets; Bronchial Provocation Tests; Bronchial S | 1987 |
[12 cases of salicylate asthma. Patients of an internal medicine practice with an allergologico-pneumologic patient sample].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Middle Aged; Nasal Polyps; Nose Neoplasms | 1987 |
Tolerance to acetylsalicylic acid (ASA) induced in ASA-sensitive asthmatics does not depend on initial adverse reaction.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Drug Tolerance; Female; | 1987 |
[Aspirin-induced asthma].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1986 |
[Value of the oral provocation test with aspirin in the diagnosis of Fernand-Widal syndrome. Apropos of 33 cases].
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Humans; Ma | 1987 |
[Bronchial asthma due to non-allergic mechanisms--pathogenesis and clinical characteristics--2) Aspirin-induced asthma].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Prostaglandins; SRS-A | 1987 |
Study of mediators of anaphylaxis in nasal wash fluids after aspirin and sodium metabisulfite nasal provocation in intolerant rhinitic patients.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Histamine; Humans; Nasal Mucosa; Nasal Provocation Tests; Rh | 1987 |
Effects of inhibition of thromboxane A2 synthesis in aspirin-induced asthma.
Topics: Acrylates; Adult; Aspirin; Asthma; Female; Humans; Male; Methacrylates; Middle Aged; Respiratory Fun | 1987 |
ASA disease: the clinical relationship of nasal polyposis to ASA intolerance.
Topics: Adolescent; Adult; Aged; Allergens; Aspirin; Asthma; Child; Drug Hypersensitivity; Female; Humans; H | 1986 |
Is coronary arterial spasm part of the aspirin-induced asthma syndrome?
Topics: Adult; Angina Pectoris, Variant; Aspirin; Asthma; Coronary Vasospasm; Electrocardiography; Humans; M | 1986 |
[Development of aspirin tolerance in hypersensitive persons. I. Methods of development of tolerance, aspirin refraction time and cross tolerance to other drugs].
Topics: Antipyrine; Aspirin; Asthma; Cross Reactions; Drug Hypersensitivity; Drug Tolerance; Humans; Indomet | 1986 |
Prevalence of aspirin intolerance in asthmatics treated in a hospital.
Topics: Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Hospitalization; Humans | 1986 |
Clinical efficacy of aspirin in "desensitised" aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Male; M | 1986 |
[Control of aspirin intolerance].
Topics: Aspirin; Asthma; Humans | 1985 |
[Characteristics of the "asthmatic triad" depending on the forms of bronchial asthma].
Topics: Adult; Aspirin; Asthma; Dinoprost; Drug Hypersensitivity; Female; Humans; Hypergammaglobulinemia; Im | 1985 |
Arachidonic acid metabolism and inhibition of cyclooxygenase in platelets from asthmatic subjects with aspirin intolerance.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Dr | 1985 |
[Demonstration of specific platelet function anomaly in asthma induced by aspirin: diagnostic consequences].
Topics: Aspirin; Asthma; Blood Platelets; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Male; Pro | 1985 |
Aspirin-sensitive asthma: abnormal platelet response to drugs inducing asthmatic attacks. Diagnostic and physiopathological implications.
Topics: Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Cyclooxygenase I | 1985 |
Increased generation of leukotriene C4 from eosinophils in asthmatic patients.
Topics: Adult; Aspirin; Asthma; Calcimycin; Eosinophils; Humans; Middle Aged; SRS-A | 1985 |
Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy.
Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Chronic Disease; Drug Hypersensitiv | 1986 |
[Bronchodilators and the preventive effect of aspirin in bronchial asthma].
Topics: Aspirin; Asthma; Bronchi; Bronchodilator Agents; Female; Humans; Male; Middle Aged | 1986 |
Exercise-induced bronchodilation in asthma.
Topics: Aspirin; Asthma; Bronchi; Constriction, Pathologic; Dilatation; Forced Expiratory Flow Rates; Humans | 1985 |
Effects of chronic aspirin ingestion in aspirin-intolerant asthmatic patients.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1985 |
Aspirin intolerance and asthmal induction of a tolerance and long-term monitoring.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Drug Tolerance; Female; | 1985 |
Challenge tests with tartrazine in patients with asthma associated with intolerance to analgesics (ASA-Triad). A comparative study with placebo.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Asthma; Azo Compounds; Drug Hypersensiti | 1985 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Asthma; Biomechanical Phenomena; Bone Diseases; Drug Hypersensiti | 1985 |
Aspirin-sensitive rhinosinusisits/asthma: spectrum of adverse reactions to aspirin.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans | 1985 |
The effect of aspirin during aspirin "desensitisation" on compound 48/80 and histamine-induced skin responses in aspirin-sensitive asthmatics.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Female; Histamine; Huma | 1985 |
Nasal polyps, bronchial asthma, and aspirin sensitivity: the Samter syndrome.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Drug Tolerance; Humans; Nasal Polyps; Platelet Aggregation; | 1985 |
[Anaphylactoid reaction to hydrocortisone succinate in three aspirin-sensitive asthmatic patients].
Topics: Adult; Anaphylaxis; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hydrocortisone; Immunoglobulin E | 1985 |
[Role of the complement system in the pathogenesis and differential diagnosis of different variants of bronchial asthma].
Topics: Adult; Aspirin; Asthma; Complement C3; Complement C4; Diagnosis, Differential; Female; Humans; Male | 1985 |
Aspirin sensitivity in asthmatics. When may this drug be safe?
Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Asthma; Child; Cross Rea | 1985 |
Bronchial hyperreactivity to histamine in aspirin sensitive asthmatics: relationship to aspirin threshold and effect of aspirin desensitisation.
Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Desensitization, Immunologic; Dose-Res | 1985 |
Amplified bronchoconstrictive oscillations in experimental asthma.
Topics: Acetaminophen; Adult; Airway Resistance; Aspirin; Asthma; Bronchial Provocation Tests; Humans; Pleth | 1985 |
[Clinical aspect of aspirin-induced asthma].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nasal Polyps; Para | 1985 |
[Effect of "Jiryu" on aspirin-induced asthma].
Topics: Adult; Aged; Aspirin; Asthma; Female; Humans; Male; Medicine, Chinese Traditional; Medicine, East As | 1985 |
Nasal symptoms in pseudoallergic reactions.
Topics: Analgesics; Aspirin; Asthma; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Nasal Mucos | 1985 |
[Diagnostic and therapeutic methods in the asthmatic triad].
Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Child; Desensitization, Immunologic | 1985 |
[Drug color-additive induced asthma in an aspirin-allergic patient].
Topics: Adult; Aspirin; Asthma; Female; Histamine Release; Humans; Hydrazines; Immunoassay | 1972 |
A patient's view of asthma.
Topics: Aspirin; Asthma; Attitude of Health Personnel; Attitude to Health; Child; Eosinophils; Female; Human | 1974 |
[Treatment of asthma].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Allergens; Anti-Bact | 1973 |
Alpha-beta-adrenergic imbalance in intrinsic-intolerance rhinitis or asthma.
Topics: Adrenergic beta-Antagonists; Anisoles; Aspirin; Asthma; Blood Coagulation Tests; Drug Hypersensitivi | 1974 |
Evaluation of IgE tests in an allergy practice.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Food Hypersensitivity; Humans; Immunoglobulin E; Immunoglobu | 1971 |
Aspirin intolerance and asthma. A clinical and immunological study.
Topics: Adult; Age Factors; Aged; Anaphylaxis; Animals; Antigens; Aspirin; Asthma; Basophils; Drug Hypersens | 1969 |
Analgesics and asthma.
Topics: Adult; Analgesics; Animals; Aspirin; Asthma; Bronchi; Child; Drug Hypersensitivity; Guinea Pigs; Hum | 1973 |
Asthma. Panel discussion. Question and answer session.
Topics: Aspirin; Asthma; Cell Membrane; Child; Cromolyn Sodium; Drug Tolerance; Humans; Mast Cells; Predniso | 1974 |
Acetylsalicylic acid intolerance.
Topics: Adult; Aged; Allergens; Animals; Antibodies; Antigens; Aspirin; Asthma; Chronic Disease; Drug Hypers | 1974 |
[Clinical aspects of drug allergy].
Topics: Adolescent; Adult; Anaphylaxis; Aspirin; Asthma; Chloramphenicol; Drug Eruptions; Drug Hypersensitiv | 1967 |
Drug allergy.
Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Aspirin; Asthma; Dermatitis, Contact; Drug | 1971 |
Aspirin disease and adverse effects.
Topics: Adult; Aspirin; Asthma; Blood Platelet Disorders; Female; Gastrointestinal Hemorrhage; Humans; Male; | 1971 |
[Study of leukergy in drug allergy].
Topics: Aminopyrine; Anaphylaxis; Angioedema; Aspirin; Asthma; Cell Aggregation; Conjunctivitis; Drug Erupti | 1971 |
[Various aspects of bronchial asthma caused by drugs].
Topics: Adolescent; Adult; Age Factors; Allergens; Anaphylaxis; Animals; Aspirin; Asthma; Drug Hypersensitiv | 1971 |
Population studies on drug hypersensitivities.
Topics: Adolescent; Adult; Age Factors; Anaphylaxis; Angioedema; Aspirin; Asthma; Barbiturates; Drug Eruptio | 1973 |
Asthma caused by FD&C approved dyes.
Topics: Acetaminophen; Adult; Angioedema; Aspirin; Asthma; Benzoates; Coloring Agents; Cough; Diethylstilbes | 1967 |
Fatal bronchial asthma: an analysis of terminal treatment in twenty cases.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Analgesics; Aspirin; Asthma; Female; Humans; Hypnotics and | 1968 |
[Use of vagotropic, sedative, antihistaminic preparations in the treatment of bronchial asthma].
Topics: Alkaloids; Aspirin; Asthma; Atropine; Ephedrine; Histamine H1 Antagonists; Humans; Phenobarbital | 1965 |
Lung disease caused by drugs.
Topics: Aspirin; Asthma; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Eosinophilia | 1969 |
The effect of some drugs on oxalic acid excretion in urine.
Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes | 1970 |
Acute anaphylactic reactions and aspirin allergy.
Topics: Adult; Anaphylaxis; Aspirin; Asthma; Desensitization, Immunologic; Drug Hypersensitivity; Epinephrin | 1971 |
[Trial of cortibucline].
Topics: Administration, Oral; Adult; Aged; Ascorbic Acid; Aspirin; Asthma; Drug Combinations; Female; Histam | 1969 |
[Aspirin intolerance in asthmatic patients].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male; Middle Aged | 1974 |
Letter: Allergy to aspirin.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Male; Middle Aged; Nasal Polyps | 1974 |
IgE mediated and non-IgE mediated allergic-type reactions to aspirin.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Animals; Antigens; Aspirin; Asthma; Child; Drug Hypersensitivi | 1974 |
Aspirin--a dangerous drug?
Topics: Aspirin; Asthma; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Humans; Legislation, Drug; Prot | 1974 |
Familial occurrence of asthma, nasal polyps and aspirin intolerance.
Topics: Adult; Aspirin; Asthma; Diseases in Twins; Drug Hypersensitivity; Environment; Female; Genotype; Hum | 1973 |
Aspirin-induced asthma in children.
Topics: Adolescent; Age Factors; Aspirin; Asthma; Child; Drug Hypersensitivity; Eczema; Eosinophils; Female; | 1973 |
A case of allergy to aspirin.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Male; Rhinitis, Allergic, Seasonal | 1973 |
[Asthma provoked by analgesics, food colors and preservatives].
Topics: Adolescent; Adult; Aged; Angioedema; Aspirin; Asthma; Azo Compounds; Benzoates; Female; Food Additiv | 1973 |
[Aspirin intolerance in a child].
Topics: Adolescent; Aspirin; Asthma; Bronchodilator Agents; Child; Drug Hypersensitivity; Fever; Humans; Mal | 1973 |
Nasal polyps.
Topics: Aspirin; Asthma; Child, Preschool; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Male; Nas | 1973 |
Aspirin and subtypes of asthma: risk factor analysis.
Topics: Adolescent; Age Factors; Aspirin; Asthma; Child; Chronic Disease; Drug Hypersensitivity; Eczema; Fem | 1973 |
[Bronchial asthma, a side effect of indomethacin which can be avoided].
Topics: Adult; Aspirin; Asthma; Humans; Indomethacin; Male; Nasal Polyps | 1973 |
Possible genetic links between cystic fibrosis of the pancreas and aspirin sensitive asthma.
Topics: Amino Acids; Animals; Aspirin; Asthma; Binding Sites; Cystic Fibrosis; Drug Hypersensitivity; Hetero | 1973 |
Letter: Asthma, nasal polyposis, and aspirin sensitivity.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Nasal Polyps; Syndrome | 1973 |
The differential effect of acetylsalicylic acid on in vitro aggregation of platelets from normal, asthmatic and aspirin-sensitive subjects.
Topics: Aspirin; Asthma; Blood Cell Count; Blood Platelets; Collagen; Densitometry; Drug Hypersensitivity; H | 1973 |
Aspirin and other cross-reacting small chemicals in known aspirin intolerant patients.
Topics: Analgesics; Antioxidants; Aspirin; Asthma; Blood Coagulation; Cross Reactions; Dose-Response Relatio | 1973 |
Familial coincidence of asthma, aspirin intolerance and nasal polyposis.
Topics: Adult; Aspirin; Asthma; Child; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nasal Polyp | 1974 |
Tween 80 exacerbated intrinsic rhinitis and asthma in non-aspirin-sensitive patients.
Topics: Aspirin; Asthma; Blood Vessels; Chemical Phenomena; Chemistry; Cholestyramine Resin; Diabetes Compli | 1974 |
[Allergic reaction to aspirin].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Middle Aged | 1974 |
Aspirin intolerance. II. A prospective study in an atopic and normal population.
Topics: Allergens; Angioedema; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Female; Humans; Male | 1974 |
Editorial: Allergy to aspirin.
Topics: Antibody Formation; Aspirin; Asthma; Drug Hypersensitivity; Humans; Prostaglandins | 1974 |
Chronic and high risk asthma in children.
Topics: Adolescent; Adrenal Cortex Hormones; Aerosols; Airway Obstruction; Aspergillosis; Aspirin; Asthma; B | 1972 |
Urticaria and asthma induced by food-and-drug additives in patients with aspirin hypersensitivity.
Topics: Adolescent; Adult; Aspirin; Asthma; Azo Compounds; Benzoates; Drug Hypersensitivity; Female; Food Ad | 1972 |
Aspirin intolerance in asthma. Detection by oral challenge.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Male; Polyps; Respir | 1972 |
Aspirin allergy.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Humans; Lymphocyte Activation; Nasal Polyps | 1971 |
Reactions to hidden agents in foods, beverages and drugs.
Topics: Adult; Allergens; Anaphylaxis; Aspirin; Asthma; Azo Compounds; Beverages; Child; Child, Preschool; C | 1971 |
Familial aspirin hypersensitivity.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male | 1971 |
Aspirin shock associated with asthma and nasal polyps.
Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Spasm; Child; Child, Preschool; Drug Hypersensitivity; | 1971 |
Are nasal polyps an allergic phenomenon?
Topics: Aspirin; Asthma; Cystic Fibrosis; Dermatitis, Atopic; Drug Hypersensitivity; Female; Humans; Hyperse | 1971 |
Aspirin-induced bronchial asthma in sisters.
Topics: Adult; Aspirin; Asthma; Female; Humans; Skin Tests | 1971 |
Concomitant nasal polyps, bronchial asthma, and aspirin sensitivity: report of three cases.
Topics: Adult; Aged; Aspirin; Asthma; Bronchial Diseases; Drug Hypersensitivity; Female; Humans; Male; Nasal | 1969 |
History of drug sensitivity in atopic persons.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Health Surveys; Penicillins; Respiratory Hypersensitivity; S | 1967 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami | 1967 |
Presidential message. The need to re-evaluate acetylsalicylic acid (aspirin).
Topics: Arthritis, Rheumatoid; Aspirin; Asthma; Binding Sites; Blood Proteins; Carbon Isotopes; Drug Hyperse | 1970 |
[Aspirin can cause asthma].
Topics: Aspirin; Asthma; Dentistry; Drug Hypersensitivity | 1970 |
[Dangerous drugs in asthma].
Topics: Antidepressive Agents; Aspirin; Asthma; Chlorpromazine; Humans; Oxygen | 1969 |
[Current treatment of asthma in adults].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aspirin; Asthma; Bronchodilator Agents; Drug Synergism; | 1969 |
Aspirin sensitivity.
Topics: Adult; Aspirin; Asthma; Child; Drug Hypersensitivity; Female; Humans; Middle Aged | 1970 |
Response of aspirin-allergic patients to challenge by some analgesics in common use.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Asthma; Dextropropoxyphene; Drug Hypersensitivity; Female | 1971 |
Intolerance to aspirin. Clinical studies and consideration of its pathogenesis.
Topics: Adult; Age Factors; Allergens; Angioedema; Aspirin; Asthma; Chemical Phenomena; Chemistry; Drug Hype | 1968 |
Acetylation of human serum albumin by acetylsalicylic acid.
Topics: Acetates; Acetrizoic Acid; Alkylation; Animals; Aspirin; Asthma; Autoradiography; Carbon Isotopes; C | 1968 |
Asthma from aspirin.
Topics: Aspirin; Asthma; Chemoreceptor Cells; Humans | 1969 |
Asthma from aspirin.
Topics: Aspirin; Asthma; Female; Humans | 1969 |
Urticaria and angio-oedema. A review of 554 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Angioedema; Aspirin; Asthma; Computers; Dermatitis, Atopic; Dr | 1969 |
[A redoubtable allergy: asthma due to aspirin].
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Male | 1965 |
[Allergic asthma and its treatment with cortisone-like acetylsalicylic acid].
Topics: Adult; Aged; Aspirin; Asthma; Female; Humans; Male; Middle Aged | 1965 |
[Minimal corticotherapy in asthma].
Topics: Ascorbic Acid; Aspirin; Asthma; Humans; Piperazines; Triamcinolone | 1965 |