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aspirin and Arteriosclerosis Obliterans

aspirin has been researched along with Arteriosclerosis Obliterans in 19 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Arteriosclerosis Obliterans: Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION.

Research Excerpts

ExcerptRelevanceReference
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."9.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."5.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
" It cannot, however, be concluded from this study that 75 mg dipyridamole in combination with 100 mg ASA tid is more effective in preventing reocclusion after PTA than in combination with 330 mg ASA tid."2.67Reocclusion prophylaxis with dipyridamole combined with acetylsalicylic acid following PTA. ( Deichsel, G; Heiss, HW; Just, H; Middleton, D, 1990)
"The effect of 7-mono-hydroxyethylrutoside and its combination with acetylsalicylic acid was evaluated in a controlled clinical trial, performed in 105 patients with obliterative atherosclerosis of the lower limbs, and using non-invasive measurement of peripheral haemodynamic parameters--blood flow during reactive hyperaemia and ankle systolic blood pressure."2.66The effect of hydroxyethylrutoside and its combination with acetylsalicylic acid in patients with obliterative atherosclerosis. ( Linhart, J; Oliva, I; Prerovský, I; Roztocil, K, 1989)
" Proved herein is the necessity of long-term administration of antiplatelet drugs in order to prevent vascular complications on the part of the heart, brain, and peripheral arteries, with a description of the drugs most commonly used for these purposes."1.36[Antiplatelet therapy in patients with chronic obliterating diseases of lower-limb arteries]. ( Dzhalilova, NS; Kuznetsov, MR; Sizarev, AV; Tepliakov, SA; Tugdumov, BV, 2010)
"Thirty-nine patients with deep vein thrombosis, 28 with arteriosclerosis obliterans, and 10 with pulmonary embolism were the subjects of this study."1.31Clinical assessment of vascular thrombosis using indium-111 platelet scintigraphy. ( Morimoto, Y; Mukai, T; Okada, M; Sugimoto, T, 2000)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's4 (21.05)18.2507
2000's4 (21.05)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, JY1
Shi, WH1
He, J1
Zhu, L1
Wang, TP1
Yu, B1
Kuznetsov, MR1
Tepliakov, SA1
Sizarev, AV1
Tugdumov, BV1
Dzhalilova, NS1
Tryniszewski, W1
Nowak, D1
Brocki, M1
Maziarz, Z1
Rysz, J1
Ogawa, S1
Mori, T1
Nako, K1
Ishizuka, T1
Ito, S1
Leo, W1
Westrych, R1
Bissinger, A1
Okraszewski, J1
Baj, Z1
Grodzińska, L1
Basista, M1
Kedzior, A1
Korbut, R1
Kostka-Trabka, E1
Gryglewski, R1
Terano, T1
Hirai, A1
Shiina, T1
Tamura, Y1
Saitoh, Y1
Salat, A1
Boehm, D1
Pulaki, S1
Murabito, M1
Berlakovich, G1
Kretschmer, G1
Mueller, MR1
Morimoto, Y1
Sugimoto, T1
Okada, M1
Mukai, T1
Zabel Langhennig, R1
Heiss, HW1
Just, H1
Middleton, D1
Deichsel, G1
Berge, PG1
Höpp, HW1
Roztocil, K1
Oliva, I1
Prerovský, I1
Linhart, J1
Strano, A2
Davì, G2
Cannizzaro, S1
Giubilato, A1
Pinto, A1
Palumbo, MG1
Gallo, V1
Mazza, A1
Rosenthal, D1
Mittenthal, MJ1
Ruben, DM1
Jones, DH1
Estes, JW1
Stanton, PE1
Lamis, PA1
Abrahamsen, AF1
Eika, C1
Godal, HC1
Lorentsen, E1
Zeitler, E1
Cavalieri, U1
Quadri, A1
Tammaro, AE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Asymptomatic Cuff Tears: A Model for Pain Development - Part B[NCT00923858]495 participants (Actual)Observational2005-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for aspirin and Arteriosclerosis Obliterans

ArticleYear
Mechanism of anti-proliferative action of eicosapentaenoic acid (EPA) in vascular cell growth: its effect on signal transduction system.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arterioscl

1997
[Prevention of obliterating arterial diseases with acetylsalicylic acid].
    Medizinische Klinik (Munich, Germany : 1983), 1990, Aug-15, Volume: 85, Issue:8

    Topics: Arteriosclerosis Obliterans; Aspirin; Coronary Artery Disease; Humans; Myocardial Infarction

1990
[Platelet function inhibitors in peripheral arteriopathies].
    Recenti progressi in medicina, 1986, Volume: 77, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; A

1986

Trials

8 trials available for aspirin and Arteriosclerosis Obliterans

ArticleYear
[A clinical trial of using antiplatelet therapy to prevent restenosis following peripheral artery angioplasty and stenting].
    Zhonghua yi xue za zhi, 2008, Mar-25, Volume: 88, Issue:12

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arteriosclerosis Obliterans; Aspirin; Cathe

2008
Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:2

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis Obliterans; Aspirin; Ch

2008
[Effect of the acetylosalicyd acid (ASA) and ticlopidine therapy on clinical condition and parameters of blood platelets in patients with peripheral arterial occlusive disease (PAOD)].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 23, Issue:137

    Topics: Adult; Aged; Arteriosclerosis Obliterans; Aspirin; Blood Platelets; Exercise Test; Female; Humans; M

2007
Reocclusion prophylaxis with dipyridamole combined with acetylsalicylic acid following PTA.
    Angiology, 1990, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Arteriosclerosis Obliterans; Aspirin; Dipyrida

1990
[Prevention of obliterating arterial diseases with acetylsalicylic acid].
    Medizinische Klinik (Munich, Germany : 1983), 1990, Aug-15, Volume: 85, Issue:8

    Topics: Arteriosclerosis Obliterans; Aspirin; Coronary Artery Disease; Humans; Myocardial Infarction

1990
The effect of hydroxyethylrutoside and its combination with acetylsalicylic acid in patients with obliterative atherosclerosis.
    Cor et vasa, 1989, Volume: 31, Issue:2

    Topics: Adult; Analgesics; Anticoagulants; Arteriosclerosis Obliterans; Aspirin; Clinical Trials as Topic; D

1989
[Platelet function inhibitors in peripheral arteriopathies].
    Recenti progressi in medicina, 1986, Volume: 77, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Anti-Inflammatory Agents; Arachidonic Acid; A

1986
Effect of acetylsalicylic acid and dipyridamole on platelet survival and aggregation in patients with atherosclerosis obliterans.
    Scandinavian journal of haematology, 1974, Volume: 13, Issue:4

    Topics: Aged; Arteriosclerosis Obliterans; Aspirin; Blood Cell Count; Blood Platelets; Cell Survival; Clinic

1974

Other Studies

10 other studies available for aspirin and Arteriosclerosis Obliterans

ArticleYear
[Antiplatelet therapy in patients with chronic obliterating diseases of lower-limb arteries].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2010, Volume: 16, Issue:1

    Topics: Arteriosclerosis Obliterans; Aspirin; Chronic Disease; Fibrinolytic Agents; Hemorrhage; Humans; Leg;

2010
Influence of pharmacological treatment on blood flow and muscle perfusion in patients with obliterative atheromatosis assessed with isotopic methods. A pilot study.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:12

    Topics: Analysis of Variance; Arteriosclerosis Obliterans; Aspirin; Blood Flow Velocity; Exercise; Female; H

2010
Fibrinolytic activity and the effects of beta-pyridylcarbinol (Ronicol) in patients with arteriosclerosis obliterans.
    Thrombosis and haemostasis, 1983, Dec-30, Volume: 50, Issue:4

    Topics: Arteriosclerosis Obliterans; Aspirin; Epoprostenol; Fibrinolysis; Humans; Leg; Platelet Aggregation;

1983
Possibility of checking compliance and efficacy of antiaggregatory treatment following femoro-popliteal vein bypass surgery.
    Thrombosis research, 1998, Jan-15, Volume: 89, Issue:2

    Topics: Anastomosis, Surgical; Arteriosclerosis Obliterans; Aspirin; Blood Coagulation; Female; Femoral Vein

1998
Clinical assessment of vascular thrombosis using indium-111 platelet scintigraphy.
    Angiology, 2000, Volume: 51, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arteriosclerosis Obliterans; Aspirin; Blood Platelet

2000
[Inhibitors of platelet aggregation in the therapy of arteriosclerosis obliterans].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, May-15, Volume: 34, Issue:10

    Topics: Arteriosclerosis Obliterans; Aspirin; Diabetic Angiopathies; Dipyridamole; Humans; Platelet Aggregat

1979
Dipyridamole and aspirin in arteriosclerosis obliterans of the lower limbs.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: Adenosine Diphosphate; Adult; Arteriosclerosis Obliterans; Aspirin; Dipyridamole; Drug Therapy, Comb

1985
The effects of aspirin, dipyridamole and warfarin in femorodistal reconstruction: long-term results.
    The American surgeon, 1987, Volume: 53, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis Obliterans; Arteriovenous Shunt, Surgical; Aspirin;

1987
[The percutaneous recanalization of arterial obliterations with Dotter's catheter (Dotter's technic)].
    Deutsche medizinische Wochenschrift (1946), 1972, Sep-15, Volume: 97, Issue:37

    Topics: Anticoagulants; Arteriosclerosis Obliterans; Aspirin; Catheterization; Collateral Circulation; Femor

1972
[Preliminary clinical uses of aspirin as an anticoagu.ant. (Preliminary note)].
    Il Policlinico. Sezione pratica, 1970, Dec-21, Volume: 77, Issue:51

    Topics: Aged; Arteriosclerosis Obliterans; Aspirin; Female; Humans; Intracranial Arteriosclerosis; Male; Mid

1970