Page last updated: 2024-10-22

aspirin and Aortic Diseases

aspirin has been researched along with Aortic Diseases in 32 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Aortic Diseases: Pathological processes involving any part of the AORTA.

Research Excerpts

ExcerptRelevanceReference
"Ticagrelor is an effective antiplatelet therapy among patients with atherosclerotic disease and, therefore, could be more effective than aspirin in preventing recurrent stroke and cardiovascular events among patients with embolic stroke of unknown source (ESUS), which includes patients with ipsilateral stenosis <50% and aortic arch atherosclerosis."9.24Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source. ( Albers, GW; Amarenco, P; Denison, H; Easton, JD; Evans, SR; Held, P; Hill, MD; Johnston, SC; Jonasson, J; Kasner, SE; Ladenvall, P; Minematsu, K; Molina, CA; Wang, Y; Wong, KSL, 2017)
"This prospective randomized controlled, open-labeled trial, with blinded end point evaluation (PROBE design) tested superiority of aspirin 75 to 150 mg/d plus clopidogrel 75 mg/d (A+C) over warfarin therapy (international normalized ratio 2-3) in patients with ischemic stroke, transient ischemic attack, or peripheral embolism with plaque in the thoracic aorta>4 mm and no other identified embolic source."9.19Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. ( Amarenco, P; Cohen, AA; Davis, S; Donnan, GA; Heiss, WD; Jones, EF; Kaste, M; Laouénan, C; Macleod, M; Young, D, 2014)
"Patients with atrial fibrillation and with documented aortic plaque who were assigned to adjusted-dose warfarin therapy (international normalized ratio 2."9.09Warfarin safety and efficacy in patients with thoracic aortic plaque and atrial fibrillation. SPAF TEE Investigators. Stroke Prevention and Atrial Fibrillation. Transesophageal echocardiography. ( Asinger, R; Blackshear, JL; Fenster, P; Halperin, J; Pearce, LA; Pennock, G; Strauss, R; Zabalgoitia, M, 1999)
"Venous thrombosis was reduced 56% by oral soluble acetylsalicylic acid and 27% by oral aspirin."5.30Some effects of prophylactic aspirins and heparins on concurrent arterial and venous thrombosis in the same animal. ( Iomhair, MM; Lavelle, SM, 1998)
"Ticagrelor is an effective antiplatelet therapy among patients with atherosclerotic disease and, therefore, could be more effective than aspirin in preventing recurrent stroke and cardiovascular events among patients with embolic stroke of unknown source (ESUS), which includes patients with ipsilateral stenosis <50% and aortic arch atherosclerosis."5.24Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source. ( Albers, GW; Amarenco, P; Denison, H; Easton, JD; Evans, SR; Held, P; Hill, MD; Johnston, SC; Jonasson, J; Kasner, SE; Ladenvall, P; Minematsu, K; Molina, CA; Wang, Y; Wong, KSL, 2017)
"This prospective randomized controlled, open-labeled trial, with blinded end point evaluation (PROBE design) tested superiority of aspirin 75 to 150 mg/d plus clopidogrel 75 mg/d (A+C) over warfarin therapy (international normalized ratio 2-3) in patients with ischemic stroke, transient ischemic attack, or peripheral embolism with plaque in the thoracic aorta>4 mm and no other identified embolic source."5.19Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques. ( Amarenco, P; Cohen, AA; Davis, S; Donnan, GA; Heiss, WD; Jones, EF; Kaste, M; Laouénan, C; Macleod, M; Young, D, 2014)
"The relationship between arch plaques and recurrent events was studied in 516 patients with ischemic stroke who were double-blindly randomized to treatment with warfarin or aspirin as part of the Patent Foramen Ovale in Cryptogenic Stroke Study (PICSS), based on the Warfarin-Aspirin Recurrent Stroke Study (WARSS)."5.14Aortic arch plaques and risk of recurrent stroke and death. ( Di Tullio, MR; Homma, S; Jin, Z; Mohr, JP; Russo, C; Sacco, RL, 2009)
"Patients with atrial fibrillation and with documented aortic plaque who were assigned to adjusted-dose warfarin therapy (international normalized ratio 2."5.09Warfarin safety and efficacy in patients with thoracic aortic plaque and atrial fibrillation. SPAF TEE Investigators. Stroke Prevention and Atrial Fibrillation. Transesophageal echocardiography. ( Asinger, R; Blackshear, JL; Fenster, P; Halperin, J; Pearce, LA; Pennock, G; Strauss, R; Zabalgoitia, M, 1999)
"The diagnosis of thoracic aortic mobile thrombus (TAMT) is rare and is usually made after debilitating embolic events."1.37Thoracic aortic mobile thrombus: is there a role for early surgical intervention? ( Ganzel, BL; Kapoor, N; Pagni, S; Ross, C; Slater, AD; Trivedi, J; Williams, M, 2011)
"Spontaneous aortic thrombosis is rare."1.35Aortic thrombosis in infancy. ( Mehta, AV; Teixeira, OH, 2009)
"Aspirin treatment had no significant effect on the neointimal smooth muscle component, but partially inhibited macrophage infiltration, without inhibiting ICAM-1 expression."1.33S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits. ( Berry, CL; Campbell, JH; Thomas, AC; Worth, NF, 2005)
"Aortic thrombus formation is rare in the patients with essential thrombocytosis (ET); therefore, no guidelines for its management have been established."1.31Medical management of a large aortic thrombus in a young woman with essential thrombocythemia. ( Agha, S; Cleary, JP; Fang, M; Lee, R; Lockridge, L; Mazur, EM, 2001)
"Venous thrombosis was reduced 56% by oral soluble acetylsalicylic acid and 27% by oral aspirin."1.30Some effects of prophylactic aspirins and heparins on concurrent arterial and venous thrombosis in the same animal. ( Iomhair, MM; Lavelle, SM, 1998)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19909 (28.13)18.7374
1990's8 (25.00)18.2507
2000's7 (21.88)29.6817
2010's7 (21.88)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
King, RW1
Dias, AP1
MukherJee, RD1
Genovese, EA1
Veeraswamy, RK1
Wooster, MD1
Amarenco, P2
Albers, GW2
Denison, H1
Easton, JD1
Evans, SR1
Held, P1
Hill, MD1
Jonasson, J1
Kasner, SE1
Ladenvall, P1
Minematsu, K1
Molina, CA1
Wang, Y1
Wong, KSL1
Johnston, SC1
Davis, S1
Jones, EF1
Cohen, AA1
Heiss, WD1
Kaste, M1
Laouénan, C1
Young, D1
Macleod, M1
Donnan, GA1
George, PM1
Di Tullio, MR1
Russo, C1
Jin, Z1
Sacco, RL1
Mohr, JP1
Homma, S1
Teixeira, OH1
Mehta, AV1
Bhindi, R1
Ormerod, OJ1
Schmidt, T1
Tsakiris, DA1
Grapow, M1
Siegemund, M1
Pagni, S1
Trivedi, J1
Ganzel, BL1
Williams, M1
Kapoor, N1
Ross, C1
Slater, AD1
Bötticher, G1
Gäbel, G1
Weiss, N1
Saeger, HD1
Bergert, H1
Avegliano, G1
Evangelista, A1
Elorz, C1
González-Alujas, T1
García del Castillo, H1
Soler-Soler, J1
Worth, NF1
Berry, CL1
Thomas, AC1
Campbell, JH1
Casella, G1
Greco, C1
Perugini, E1
Pallotti, MG1
Pavesi, PC1
Di Pasquale, G1
Leffert, RL1
Hackett, RL1
Hagen, PO1
Wang, ZG1
Mikat, EM1
Hackel, DB1
Schaub, RG1
Gates, KA1
Roberts, RE1
Ricou, FJ1
Arroyo, JF1
Manning, WJ1
Iomhair, MM1
Lavelle, SM1
Blackshear, JL1
Zabalgoitia, M1
Pennock, G1
Fenster, P1
Strauss, R1
Halperin, J1
Asinger, R1
Pearce, LA1
Poliantsev, AA1
Spasov, AA1
Mozgovoĭ, PV1
Karpenko, AV1
Shcherbakov, VN1
Kuznetsov, VI1
Khomutnikova, AI1
Kirichenko, OM1
Fang, M1
Agha, S1
Lockridge, L1
Lee, R1
Cleary, JP1
Mazur, EM1
Pick, R1
Chediak, J1
Glick, G1
Pokrovskiĭ, AV2
Dmitrieva, VA1
Aleksandrova, NP2
Kovalenko, VI2
Il'in, SG1
Scriven, AJ1
Lidbury, PS1
Nathan, AW1
Fuster, V1
Badimon, L1
Badimon, JJ1
Ip, JH1
Chesebro, JH1
Függer, R1
Prager, M1
Sautner, T1
Kretschmer, G1
Polterauer, P1
Lewin, J1
Swedenborg, J1
Egberg, N1
Vesterqvist, O1
Green, K1
Pion, PD1
Pujadas, R1
Escrivá, E1
Fernández, F1
Jané, J1
Argimón, J1
Fava, P1
Galera, MC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised, Double-Blind, Multinational Study to Prevent Major Vascular Events With Ticagrelor Compared to Aspirin (ASA) in Patients With Acute Ischaemic Stroke or TIA.[NCT01994720]Phase 313,307 participants (Actual)Interventional2014-01-07Completed
Prevention of New Vascular Events in Patients With Brain Infarction or Peripheral Embolism and Thoracic Aortic Plaques ≥ 4 mm in Thickness in the Aortic Arch or Descending Aortic Upstream to the Embolized Artery[NCT00235248]Phase 3350 participants (Actual)Interventional2002-02-28Completed
Patent Foramen Ovale in Cryptogenic Stroke Study[NCT00697151]Phase 4630 participants (Actual)Interventional1993-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

EQ-5D (EuroQol Five Dimensions Questionnaire) at End of Treatment Visit

"EQ-5D index score using the UK tariff.~EQ-5D is a self assessment of 5 dimensions: mobility, self-care, usual activities, pain and discomfort, and anxiety and depression. For each dimension responders are asked to state their status on a three level ordinal scale; whether they experience no problems (Level 1), some problems (Level 2) or severe problems (Level 3). Health states defined by the 5 dimensions can be converted into a weighted health state index (health state utility) by applying scores from the EQ-5D value sets elicited from general population samples.~The higher the index score the better the health state. In this study index scores ran from -0.59 to 1." (NCT01994720)
Timeframe: End of treatment visit (Day 90+-7d)

InterventionIndex score (Mean)
Ticagrelor 90 mg0.85
ASA 100 mg0.84

EQ-5D (EuroQol Five Dimensions Questionnaire) at Premature Treatment Discontinuation Visit

"EQ-5D index score using the UK tariff.~EQ-5D is a self assessment of 5 dimensions: mobility, self-care, usual activities, pain and discomfort, and anxiety and depression. For each dimension responders are asked to state their status on a three level ordinal scale; whether they experience no problems (Level 1), some problems (Level 2) or severe problems (Level 3). Health states defined by the 5 dimensions can be converted into a weighted health state index (health state utility) by applying scores from the EQ-5D value sets elicited from general population samples.~The higher the index score the better the health state. In this study index scores ran from -0.59 to 1." (NCT01994720)
Timeframe: Premature treatment discontinuation visit(<15 days after last dose)

InterventionIndex score (Mean)
Ticagrelor 90 mg0.72
ASA 100 mg0.68

EQ-5D at Visit 1 (Enrolment)

"EQ-5D (EuroQol five dimensions questionnaire) index score using the UK tariff.~EQ-5D is a self assessment of 5 dimensions: mobility, self-care, usual activities, pain and discomfort, and anxiety and depression. For each dimension responders are asked to state their status on a three level ordinal scale; whether they experience no problems (Level 1), some problems (Level 2) or severe problems (Level 3). Health states defined by the 5 dimensions can be converted into a weighted health state index (health state utility) by applying scores from the EQ-5D value sets elicited from general population samples.~The higher the index score the better the health state. In this study index scores ran from -0.59 to 1." (NCT01994720)
Timeframe: Visit 1 (Enrolment)

InterventionIndex score (Mean)
Ticagrelor 90 mg0.70
ASA 100 mg0.70

EQ-5D at Visit 2 (Day 7+-2d)

"EQ-5D (EuroQol five dimensions questionnaire) index score using the UK tariff.~EQ-5D is a self assessment of 5 dimensions: mobility, self-care, usual activities, pain and discomfort, and anxiety and depression. For each dimension responders are asked to state their status on a three level ordinal scale; whether they experience no problems (Level 1), some problems (Level 2) or severe problems (Level 3). Health states defined by the 5 dimensions can be converted into a weighted health state index (health state utility) by applying scores from the EQ-5D value sets elicited from general population samples.~The higher the index score the better the health state. In this study index scores ran from -0.59 to 1." (NCT01994720)
Timeframe: Visit 2 (Day 7+-2d)

InterventionIndex score (Mean)
Ticagrelor 90 mg0.80
ASA 100 mg0.79

Net Clinical Outcome

Participants with stroke, MI, death or life-threatening bleeding. If no event, censoring occures at the minimum of (last date of event assessment, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg457
ASA 100 mg508

Number of Participants by Severity of Stroke and Overall Disability

"Analysis of severity of stroke and overall disability of patients, using the modified Rankin Score, mRS.~Modified Rankin Score:~0 - No symptoms.~- No significant disability. Able to carry out all usual activities, despite some symptoms.~- Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous activities.~- Moderate disability. Requires some help, but able to walk unassisted.~- Moderately severe disability. Unable to attend to own bodily needs without assistance, and unable to walk unassisted.~- Severe disability. Requires constant nursing care and attention, bedridden, incontinent.~- Dead.~Disability defined as mRS > 1.~Odds ratio and p-value are calculated for ticagrelor versus ASA from a logistic regression model with treatment group, history of stroke and NIHSS (National Institutes of Health Stroke Scale) at baseline as explanatory variables." (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg1107
ASA 100 mg1194

Number of Participants With All-Cause Death

Participants with all-cause death. If no event, censoring at the minimum of (last date of event assessment, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg68
ASA 100 mg58

Number of Participants With Composite of Ischaemic Stroke, MI and CV Death

Participants with ischaemic stroke, MI or CV death. If no event, censoring at the minimum of (last date of event assessment, date of death from non-CV causes, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg423
ASA 100 mg475

Number of Participants With Composite of Stroke/MI/Death

Participants with stroke, MI or death. If no event, censoring occures at the minimum of (last date of event assessment, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg442
ASA 100 mg497

Number of Participants With CV Death

Participants with CV death. If no event, censoring at the minimum of (last date of event assessment, date of death from non-CV causes, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg41
ASA 100 mg35

Number of Participants With Disabling Stroke

Participants with disabling stroke. If no event, censoring at the minimum of (last date of event assessment, date of death, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg277
ASA 100 mg307

Number of Participants With Fatal Stroke

Participants with fatal stroke. If no event, censoring at the minimum of (last date of event assessment, date of death from non-CV causes, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg18
ASA 100 mg17

Number of Participants With Ischaemic Stroke

Participants with ischaemic stroke. If no event, censoring occures at the minimum of (last date of event assessment, date of death, end of treatment date, day 97). (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg385
ASA 100 mg441

Number of Participants With MI

Participants with MI. If no event, censoring at the minimum of (last date of event assessment, date of death, end of treatment date, day 97) (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg25
ASA 100 mg21

Number of Participants With PLATO Major Bleeding Event

"Participants with PLATO Major bleeding. If no event, censoring occures at the minimum of (last date of event assessment, date of death, end of treatment date, day 97).~PLATO Major bleeding is defined as a bleed that is any one of:~Fatal~Intracranial (excluding asymptomatic haemorrhagic transformations of ischemic brain infarctions and excluding micro-hemorrhages <10 mm evident only on gradient-echo MRI)~Intrapericardial bleed with cardiac tamponade~Hypovolaemic shock or severe hypotension due to bleeding and requiring pressors or surgery~Significantly disabling (eg. intraocular with permanent vision loss)~Clinically overt or apparent bleeding associated with a decrease in Hb of more than 30 g/L (1.9 mmol/L; 0.465 mmol/L)~Transfusion of 2 or more units (whole blood or packed red blood cells [PRBCs]) for bleeding." (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg31
ASA 100 mg38

Number of Participants With Premature Discontinuation of Study Drug Due to Any Bleeding Adverse Event

Participants discontinuation of study drug due to any bleeding adverse event. If no event, censoring occures at the minimum of (last date of event assessment, date of death, end of treatment date, day 97). (NCT01994720)
Timeframe: Time from first dose and up to and including 7 days following the date of last dose of the study

InterventionParticipants (Number)
Ticagrelor 90 mg82
ASA 100 mg37

Number of Participants With Stroke

Participants with stroke. If no event, censoring at the minimum of (last date of event assessment, date of death, end of treatment date, day 97) (NCT01994720)
Timeframe: From randomization up to 97 days

InterventionParticipants (Number)
Ticagrelor 90 mg390
ASA 100 mg450

Change in NIHSS

"Change from baseline to end of treatment visit in NIHSS (National Institutes of Health Stroke Scale):~0 No stroke symptoms 1-4 Minor stroke 5-15 Moderate stroke 16-20 Moderate to severe stroke 21-42 Severe stroke." (NCT01994720)
Timeframe: From randomization up to 97 days

,
InterventionParticipants (Number)
<=-5-4-3-2-1012345>5Missing
ASA 100 mg1274388101073113168379311611614450
Ticagrelor 90 mg1324037791088109968167281813610474

Reviews

5 reviews available for aspirin and Aortic Diseases

ArticleYear
[Antithrombotic therapy after peripheral vascular treatment: what is evidence-based?].
    Zentralblatt fur Chirurgie, 2012, Volume: 137, Issue:5

    Topics: Aortic Diseases; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Dose-Response Relations

2012
[Atheromatosis of the thoracic aorta and risk of stroke].
    Giornale italiano di cardiologia (2006), 2006, Volume: 7, Issue:5

    Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Aspirin; Atherosclerosis; Clopidogrel; Controlled

2006
[Diagnosis and treatment of cerebrovascular accidents of cardioembolic origin].
    Praxis, 1996, Feb-06, Volume: 85, Issue:6

    Topics: Aged; Anticoagulants; Aortic Diseases; Arteriosclerosis; Aspirin; Atrial Fibrillation; Cardiomyopath

1996
Role of transesophageal echocardiography in the management of thromboembolic stroke.
    The American journal of cardiology, 1997, Aug-28, Volume: 80, Issue:4C

    Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Aspirin; Cerebrovascular Disorde

1997
The porcine model for the understanding of thrombogenesis and atherogenesis.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Aspirin; Coronary

1991

Trials

7 trials available for aspirin and Aortic Diseases

ArticleYear
Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source.
    Stroke, 2017, Volume: 48, Issue:9

    Topics: Adenosine; Aged; Aortic Diseases; Aspirin; Atherosclerosis; Carotid Stenosis; Female; Humans; Intrac

2017
Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques.
    Stroke, 2014, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aorta, Thoracic; Aortic Diseases; Aspirin; Brain Ischemia;

2014
Aortic arch plaques and risk of recurrent stroke and death.
    Circulation, 2009, May-05, Volume: 119, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Diseases; Aspirin; Atherosclerosis; Death; D

2009
Transesophageal echocardiographic correlates of thromboembolism in high-risk patients with nonvalvular atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography.
    Annals of internal medicine, 1998, Apr-15, Volume: 128, Issue:8

    Topics: Aged; Anticoagulants; Aortic Diseases; Arteriosclerosis; Aspirin; Atrial Fibrillation; Drug Therapy,

1998
Warfarin safety and efficacy in patients with thoracic aortic plaque and atrial fibrillation. SPAF TEE Investigators. Stroke Prevention and Atrial Fibrillation. Transesophageal echocardiography.
    The American journal of cardiology, 1999, Feb-01, Volume: 83, Issue:3

    Topics: Aged; Anticoagulants; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Aspirin; Atrial Fibrillati

1999
[Blood rheological disorders in atherosclerotic lesion of the abdominal aorta and their correction by the use of aspirin].
    Kardiologiia, 1979, Volume: 19, Issue:2

    Topics: Adult; Aged; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Aspirin; Blood Circulation; Clinic

1979
[Synthetic vascular reconstructions in the pelvis: function and survival].
    VASA. Supplementum, 1990, Volume: 30

    Topics: Aortic Diseases; Arterial Occlusive Diseases; Aspirin; Blood Vessel Prosthesis; Combined Modality Th

1990

Other Studies

20 other studies available for aspirin and Aortic Diseases

ArticleYear
Staging Endovascular Thoracic and Thoracoabdominal Aortic Aneurysm Repairs and the Risk of Post-operative Spinal Cord Ischemia.
    Annals of vascular surgery, 2022, Volume: 85

    Topics: Aortic Aneurysm, Thoracic; Aortic Diseases; Aspirin; Blood Vessel Prosthesis Implantation; Endovascu

2022
Aortic arch atheroma: a plaque of a different color or more of the same?
    Stroke, 2014, Volume: 45, Issue:5

    Topics: Anticoagulants; Aortic Diseases; Aspirin; Clopidogrel; Female; Humans; Male; Platelet Aggregation In

2014
Aortic thrombosis in infancy.
    Tennessee medicine : journal of the Tennessee Medical Association, 2009, Volume: 102, Issue:4

    Topics: Anticoagulants; Aortic Diseases; Aspirin; Echocardiography, Doppler; Enoxaparin; Female; Humans; Inf

2009
Letter by Bhindi and Ormerod regarding article, "Aortic arch plaques and risk of recurrent stroke and death".
    Circulation, 2010, Jan-19, Volume: 121, Issue:2

    Topics: Anticoagulants; Aortic Diseases; Aspirin; Atherosclerosis; Fibrinolytic Agents; Humans; Hydroxymethy

2010
[Thrombotic microangiopathy after extracorporeal circulation: important differential diagnosis].
    Der Anaesthesist, 2011, Volume: 60, Issue:5

    Topics: ADAM Proteins; ADAMTS13 Protein; Aged, 80 and over; Aortic Diseases; Aspirin; Coma; Critical Care; D

2011
Thoracic aortic mobile thrombus: is there a role for early surgical intervention?
    The Annals of thoracic surgery, 2011, Volume: 91, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Diseases; Aspirin; Echocardiography, Transes

2011
Acute peripheral arterial ischemia and suspected aortic dissection: usefulness of transesophageal echocardiography in differential diagnosis with aortic thrombosis.
    The American journal of cardiology, 2002, Sep-15, Volume: 90, Issue:6

    Topics: Acute Disease; Adult; Aged; Amputation, Surgical; Anticoagulants; Aortic Diseases; Arterial Occlusiv

2002
S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits.
    Atherosclerosis, 2005, Volume: 183, Issue:1

    Topics: Animals; Aortic Diseases; Aspirin; Atherosclerosis; Catheterization; Diet, Atherogenic; Drug Evaluat

2005
Aspergillus aortitis following replacement of aortic valve.
    The Journal of thoracic and cardiovascular surgery, 1967, Volume: 53, Issue:6

    Topics: Adult; Aortic Diseases; Aspergillus; Aspirin; Cardiac Catheterization; Cephalothin; Extracorporeal C

1967
Antiplatelet therapy reduces aortic intimal hyperplasia distal to small diameter vascular prostheses (PTFE) in nonhuman primates.
    Annals of surgery, 1982, Volume: 195, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Diseases; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Dipyr

1982
Effect of aspirin on collateral blood flow after experimental thrombosis of the feline aorta.
    American journal of veterinary research, 1982, Volume: 43, Issue:9

    Topics: Animals; Aortic Diseases; Aspirin; Cat Diseases; Cats; Collateral Circulation; Hindlimb; Platelet Ag

1982
Some effects of prophylactic aspirins and heparins on concurrent arterial and venous thrombosis in the same animal.
    Thrombosis research, 1998, Dec-01, Volume: 92, Issue:5

    Topics: Animals; Aortic Diseases; Aspirin; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Rats; Rats, S

1998
[Prevention of early thrombotic complications after reconstructive operations in occlusions of the aorto-iliac segment].
    Khirurgiia, 2000, Issue:9

    Topics: Adult; Aged; Anticoagulants; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Aspirin

2000
Medical management of a large aortic thrombus in a young woman with essential thrombocythemia.
    Mayo Clinic proceedings, 2001, Volume: 76, Issue:4

    Topics: Aorta, Abdominal; Aortic Diseases; Aspirin; Biopsy, Needle; Drug Therapy, Combination; Female; Follo

2001
Aspirin inhibits development of coronary atherosclerosis in cynomolgus monkeys (Macaca fascicularis) fed an atherogenic diet.
    The Journal of clinical investigation, 1979, Volume: 63, Issue:1

    Topics: Animals; Aortic Diseases; Arteriosclerosis; Aspirin; Coronary Disease; Diet, Atherogenic; Haplorhini

1979
[Correction of disorders of rheologic properties of blood in reconstructive operations on the abdominal aorta].
    Khirurgiia, 1978, Issue:10

    Topics: Adult; Aged; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Aspirin; Blood Viscosity; Dipyrida

1978
Effects of laser-generated tissue debris on aggregation of human platelets.
    American heart journal, 1991, Volume: 122, Issue:3 Pt 1

    Topics: Aged; Angioplasty, Laser; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Aspirin; Blood Coagulat

1991
Effect of acetyl salicylic acid on increased production of thromboxane after aortic graft surgery.
    European journal of vascular surgery, 1989, Volume: 3, Issue:3

    Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Arterial Occlusive Diseases; Aspirin; Bloo

1989
Feline aortic thromboemboli: t-PA thrombolysis followed by aspirin therapy and rethrombosis.
    The Veterinary clinics of North America. Small animal practice, 1988, Volume: 18, Issue:1

    Topics: Animals; Aortic Diseases; Aspirin; Cat Diseases; Cats; Female; Recurrence; Thromboembolism; Tissue P

1988
[Effect of various doses of aspirin on the development of aseptic thrombotic aortic endocarditis experimentally induced in the rabbit].
    Revista espanola de cardiologia, 1988, Volume: 41, Issue:1

    Topics: Animals; Aortic Diseases; Aspirin; Cardiac Catheterization; Disease Models, Animal; Dose-Response Re

1988