aspirin and Anterior Choroidal Artery Infarction studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

Excerpt	Relevance	Reference
"We compared the risk of recurrent ischemic stroke, vascular events, and major bleeding between DAPT with cilostazol plus aspirin or clopidogrel and aspirin or clopidogrel alone in patients with ischemic stroke between 8 and 180 days before starting trial treatment and ECAS or without arterial stenosis."	9.69	Dual antiplatelet therapy with cilostazol in stroke patients with extracranial arterial stenosis or without arterial stenosis: A subgroup analysis of the CSPS.com trial. ( Hoshino, H; Kimura, K; Kitagawa, K; Minematsu, K; Okamura, S; Omae, K; Toyoda, K; Uchiyama, S; Yamaguchi, T, 2023)
"In the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial, acute treatment with clopidogrel-aspirin was associated with significantly reduced risk of recurrent stroke."	9.51	Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy: A Post Hoc Analysis of a Randomized Clinical Trial. ( de Havenon, A; Easton, JD; Henninger, N; Johnston, SC; Kim, AS; Kvernland, A; Liberman, AL; Mac Grory, B; Rostanski, SK; Yaghi, S, 2022)
"The study aimed to evaluate the clinical efficacy of the Huo Xue Hua Yu method combined with aspirin in the treatment of patients with acute cerebral infarction (ACI)."	9.41	Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A Systematic Evaluation and Meta-analysis. ( Chen, C; Liu, X; Ma, F; Tang, Q; Wen, X; Wu, Y, 2023)
"P2Y12 receptor inhibitor plus aspirin vs aspirin given within 24 h after acute noncardioembolic ischemic stroke or TIA reduces the risk of subsequent stroke."	9.22	P2Y12 receptor inhibitor plus aspirin versus aspirin treated within 24 hours of acute noncardioembolic ischemic stroke or TIA: Meta-analysis. ( Huang, WY; Lee, M; Ovbiagele, B, 2022)
"The objective of this study was to evaluate the efficacy and safety of intravenous vinpocetine administration as part of a comprehensive treatment for acute cerebral infarction in a Chinese population."	9.22	Efficacy and Safety of Vinpocetine as Part of Treatment for Acute Cerebral Infarction: A Randomized, Open-Label, Controlled, Multicenter CAVIN (Chinese Assessment for Vinpocetine in Neurology) Trial. ( Hu, H; Huang, Y; Kong, Y; Li, C; Li, Y; Nao, J; Song, Y; Tan, L; Zhang, J; Zhang, W, 2016)
"The results of the Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS), a randomized double-blind study of sarpogrelate (selective 5-HT(2A) receptor antagonist) versus aspirin in 1510 Japanese patients, have been reported."	9.14	Sarpogrelate versus aspirin in secondary prevention of cerebral infarction: differential efficacy in diabetes? Subgroup analysis from S-ACCESS. ( Nishimaru, K; Shinohara, Y, 2009)
"Patients aged 20-79 years who had had a cerebral infarction within the previous 26 weeks were enrolled at 278 sites in Japan and allocated to receive 100 mg cilostazol twice daily or 81 mg aspirin once daily for 1-5 years."	9.14	Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial. ( Genka, C; Hamada, C; Handa, S; Katayama, Y; Kitagawa, Y; Koretsune, Y; Kusuoka, H; Matsuoka, K; Nishimaru, K; Ohashi, Y; Sawada, T; Shinohara, Y; Tanahashi, N; Tsushima, M; Uchiyama, S; Yamaguchi, T; Yamamoto, H, 2010)
"To observe the clinical value of protoparaxotril saporlirs (PTS) combined with aspirin in the secondary prevention of cerebral infarction."	9.13	[Clinical value of protoparaxotril saporlirs combined with aspirin in the secondary prevention of cerebral infarction]. ( Liu, ZF; Xu, ZQ; Zhou, BR, 2008)
"To investigate the effects of puerarin with aspirin on the markers of damaged vascular endothelial cells, as von Willebrand factor (vWF), and thrombomodulin (TM) in patients with acute cerebral infarction (ACI)."	9.13	[Effects of puerarin with aspirin on the markers of damaged vascular endothelial cells in patients with acute cerebral infarction]. ( Ding, MP; Fen, F; Hu, HT, 2008)
"In total, 1510 patients with recent cerebral infarction (1 week to 6 months after onset) were randomly assigned to receive either sarpogrelate (100 mg TID) or aspirin (81 mg/d)."	9.13	Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A randomized, double-blind, aspirin-controlled trial. ( Fukuuchi, Y; Gotoh, F; Handa, S; Hayashi, K; Hirai, S; Kobayashi, S; Kondo, K; Nishimaru, K; Otomo, E; Sawada, T; Shinohara, Y; Terashi, A; Tohgi, H; Uchiyama, S; Yamaguchi, T, 2008)
"Patients experiencing acute ischemic stroke or transient ischemic attack are commonly treated with clopidogrel and/or aspirin (mono- and dual-antiplatelet therapy) to minimize the risk for recurrent stroke."	9.12	Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis. ( Huang, Z; Yang, Y; Zhang, X, 2021)
"Fluctuations in urinary 11-DTB2 after cerebral infarction in blacks do not correlate with changes in aspirin doses, except perhaps when the dose changes by a factor of 4 or more."	9.11	Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. ( Bang, NU; Bruno, A; Cohen, SN; Gorelick, PB; McConnell, JP; Tietjen, GE; Wallis, RA, 2004)
"This pilot trial has not found differences between triflusal and aspirin in the prevention of vascular complications after TIA or ischemic stroke, although given the wide CI, potentially important group differences could not be ruled out."	9.11	Triflusal vs aspirin for prevention of cerebral infarction: a randomized stroke study. ( Abiusi, G; Bauso-Tosselli, L; Culebras, A; Domínguez, R; Famulari, A; Ferrari, J; Gori, H; Reich, E; Rey, R; Rotta-Escalante, R; Vila, J, 2004)
"We performed a randomized, double-blind, multicenter study to test the efficacy of triflusal (600 mg/d) versus aspirin (325 mg/d) for prevention of vascular events in patients with stroke or transient ischemic attack (Triflusal versus Aspirin in Cerebral Infarction Prevention [TACIP])."	9.10	Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial. ( Alvarez-Sabín, J; Ferro, JM; Jiménez, MD; Lago, A; Matías-Guiu, J; Melo, T; Torres, F, 2003)
"To compare the efficacy and safety of two antiplatelet regimens, ticlopidine alone (200 mg daily) and ticlopidine (100 mg daily) plus aspirin (81 mg daily), in patients with ischemic stroke from the Tokai district of Japan."	9.10	Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke. ( Ito, E; Kuzuhara, S; Nakajima, M; Takahashi, A; Uchiyama, S; Yamamoto, H, 2003)
"We determined the percentages of fibrinogen-bound and P-selectin-expressed platelets in whole blood using flow cytometry in 254 patients with various cerebral infarction subtypes, as well as in 30 age-matched controls."	9.09	Measurement of platelet fibrinogen binding and p-selectin expression by flow cytometry in patients with cerebral infarction. ( Iwata, M; Uchiyama, S; Yamazaki, M, 2001)
"We examined the effect of aspirin on the enhanced erythrocyte aggregability in 19 patients with cerebral infarction during the chronic phase."	9.08	Aspirin improves the enhanced erythrocyte aggregability in patients with cerebral infarction. ( Fukuuchi, Y; Kobari, M; Takeda, H; Tanahashi, N; Tomita, M; Yokoyama, M, 1996)
"Previous studies have shown that various aspirin combinations might be beneficial for the treatment of acute cerebral infarction (ACI)."	9.01	Effects of six types of aspirin combination medications for treatment of acute cerebral infarction in China: A network meta-analysis. ( Fan, J; Jin, L; Sheng, J; Shi, W; Xu, L; Yuan, H; Yuan, Y; Zhou, J, 2019)
"While previous meta-analysis have investigated the efficacy of cilostazol in the secondary prevention of ischemic stroke, they were criticized for their methodology, which confused the acute and chronic phases of stroke."	8.90	The efficacy and safety of cilostazol for the secondary prevention of ischemic stroke in acute and chronic phases in Asian population--an updated meta-analysis. ( Chen, S; Malaguit, J; Pu, J; Shi, L; Xu, L; Zhang, J, 2014)
" Patients aged 80 years or older who received monotherapy with clopidogrel or aspirin following hospitalization for primary acute ischemic stroke between January 1, 2009, and December 31, 2018, were included."	8.12	Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke. ( Huang, HY; Katz, AJ; Lin, FJ; Lin, SY; Sheu, JJ; Wang, CC; Wu, CH, 2022)
" Here, we report the case of an 82-year-old Japanese woman with normal renal function who developed multiple cerebral infarctions due to CAT that grew rapidly, associated with inflammation from an antecedent infection, and diminished rapidly by detachment of fibrin on the mass surface and antithrombotic drugs."	8.12	Multiple cerebral infarctions due to calcified amorphous tumor growing rapidly from an antecedent infection and decreasing rapidly by detachment of fibrin and antithrombotic drugs: a case report. ( Doyu, M; Ito, H; Kimura, M; Matsuyama, K; Niwa, JI, 2022)
"We investigated (1) the associations of pre-stroke aspirin use with thrombus burden, infarct volume, hemorrhagic transformation, early neurological deterioration (END), and functional outcome, and (2) whether stroke subtypes modify these associations in first-ever ischemic stroke."	8.02	Relation of Pre-Stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes. ( Bae, HJ; Cha, JK; Cho, YJ; Choi, KH; Han, MK; Hong, KS; Jeong, SW; Kang, K; Kim, BJ; Kim, DE; Kim, DH; Kim, JG; Kim, JT; Lee, BC; Lee, J; Lee, KB; Lee, SJ; Nahrendorf, M; Oh, MS; Park, HK; Park, JM; Park, MS; Park, SS; Park, TH; Ryu, WS; Schellingerhout, D; Yu, KH, 2021)
"To investigate the association of aspirin resistance (AR) with the plasma 4-hydroxynonenal (4-HNE) level and its impact on recurrent cerebral infarction (CI) in patients with acute cerebral infarction (ACI) who were receiving aspirin therapy."	7.96	Association of aspirin resistance with 4-hydroxynonenal and its impact on recurrent cerebral infarction in patients with acute cerebral infarction. ( Feng, J; Guo, J; Guo, Y; Wang, J, 2020)
"Atorvastatin and aspirin have been used in treating different forms of epilepsy."	7.96	Effects of atorvastatin and aspirin on post-stroke epilepsy and usage of levetiracetam. ( Ding, Y; Feng, X; Lin, W; Zhao, T; Zhou, C, 2020)
"BACKGROUND To investigate the combination of beraprost sodium (BPS) and aspirin in the treatment of acute ischemic stroke (AIS)."	7.85	Beneficial Effect of Beraprost Sodium Plus Aspirin in the Treatment of Acute Ischemic Stroke. ( Chen, S; Chen, W; He, W; Li, S; Wei, D; Xie, S, 2017)
"To explore the correlation between the recurrence of cerebral infarction and aspirin resistance (AR)/Chinese medical (CM) constitutions."	7.81	[Recurrence of Cerebral Infarction Associated Aspirin Resistance or Chinese Medical Constitutions: a Correlation Study]. ( Li, YH; Lu, QA; Wang, DX; Wang, XC; Yu, LH; Zong, SJ, 2015)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."	7.80	Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
"To investigate the relationship between aspirin resistance and clinical and neuroimaging measures of stroke severity in acute stroke patients."	7.79	Association of aspirin resistance with increased stroke severity and infarct size. ( Churilov, L; Colley, RE; Davis, SM; Goh, C; Yan, B; Zheng, AS, 2013)
"Treatment with cilostazol for 7 days before ischemia significantly suppressed the risk and severity of cerebral hemorrhage after injection of tissue-type plasminogen activator, although treatment with aspirin had no such protective effect compared with nontreated mice."	7.78	Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model. ( Kasahara, Y; Matsuyama, T; Nakagomi, T; Stern, D; Taguchi, A, 2012)
"9 years) with confirmed diagnoses of cerebral infarction and PAS, treated with anticoagulants (n = 54) or aspirin (n = 38) were retrospectively analyzed."	7.77	[Aspirin versus anticoagulation in young patients with cerebral infarction secondary to primary antiphospholipid syndrome]. ( Arauz, A; Artigas, C; Barinagarrementeria, F; Cantu-Brito, C; Hernandez, B; Marquez, JM; Merlos, M; Perez, A; Roa, LF, 2011)
"Endoscopy reveals low-dose aspirin-induced gastroduodenal injuries in patients with cerebral infarction."	7.76	Investigation of gastroduodenal mucosal injuries caused by low-dose aspirin therapy in patients with cerebral infarction. ( Kato, M; Nema, H, 2010)
"We report a case in which hemorrhage occurred in an asymptomatic falx meningioma known beforehand, after the internal use of low-dose aspirin for 16 months."	7.74	Hemorrhage from a falx meningioma after internal use of low-dose aspirin. ( Miyazawa, T; Shima, K; Toyooka, T; Uozumi, Y, 2008)
"A Markov model was developed to calculate the health outcomes and associated costs for 65-year-old patients with cerebral infarction who were treated with 200 mg/day cilostazol or 81 mg/day aspirin."	7.73	Pharmacoeconomic analysis of cilostazol for the secondary prevention of cerebral infarction. ( Inoue, T; Kobayashi, M; Uchiyama, S; Uetsuka, Y, 2006)
"This follow-up study was designed to evaluate whether the use of aspirin either before or after aneurysm rupture affects the occurrence of delayed cerebral ischemia."	7.69	Aspirin and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Juvela, S, 1995)
"Thromboxane A2 (TXA2) biosynthesis was studied in healthy subjects, patients with chronic cerebral infarction, patients under chronic aspirin treatment and patients with atrial fibrillation."	7.68	Urinary 11-dehydro-thromboxane B2: a quantitative index of platelet activation in cerebral infarction. ( Hayashi, Y; Nakahama, H; Nakanishi, T; Shimizu, S; Sugita, M; Takiguchi, A; Uyama, O; Yamamoto, S, 1992)
"The effects of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1H)-quinolinone (cilostazol, OPC-13013), acetylsalicylic acid (ASA) and ifenprodil on experimentally induced cerebral infarction were studied in anesthetized rabbits."	7.67	Effect of cilostazol on experimental cerebral infarction in rabbits. ( Kimura, Y; Nakase, H; Watanabe, K, 1986)
" As for intracranial hemorrhage (ICH), stroke recurrence, and adverse event (AE) rate, there were no significant differences of efficacy among 7 drug therapies."	6.58	Aspirin plus dipyridamole has the highest surface under the cumulative ranking curves (SUCRA) values in terms of mortality, intracranial hemorrhage, and adverse event rate among 7 drug therapies in the treatment of cerebral infarction. ( Liu, X; Zhang, JJ, 2018)
"We compared the risk of recurrent ischemic stroke, vascular events, and major bleeding between DAPT with cilostazol plus aspirin or clopidogrel and aspirin or clopidogrel alone in patients with ischemic stroke between 8 and 180 days before starting trial treatment and ECAS or without arterial stenosis."	5.69	Dual antiplatelet therapy with cilostazol in stroke patients with extracranial arterial stenosis or without arterial stenosis: A subgroup analysis of the CSPS.com trial. ( Hoshino, H; Kimura, K; Kitagawa, K; Minematsu, K; Okamura, S; Omae, K; Toyoda, K; Uchiyama, S; Yamaguchi, T, 2023)
"This study was performed to investigate whether ticagrelor/aspirin versus clopidogrel/aspirin can further reduce the residual risk of stroke recurrence in patients with positive diffusion-weighted imaging (DWI) in the High-Risk Patients with Acute Nondisabling Cerebrovascular Events II (CHANCE-2) trial."	5.69	Genotype-Guided Dual Antiplatelet Use for Transient Ischemic Attack and Minor Stroke by Imaging Status: Subgroup Analysis of the CHANCE-2 Trial. ( Bath, PM; Jiang, Y; Jing, J; Johnston, SC; Li, H; Li, Z; Liu, L; Meng, X; Wang, A; Wang, Y; Xie, X; Xu, Q; Zhao, X, 2023)
"In the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial, acute treatment with clopidogrel-aspirin was associated with significantly reduced risk of recurrent stroke."	5.51	Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy: A Post Hoc Analysis of a Randomized Clinical Trial. ( de Havenon, A; Easton, JD; Henninger, N; Johnston, SC; Kim, AS; Kvernland, A; Liberman, AL; Mac Grory, B; Rostanski, SK; Yaghi, S, 2022)
"Aspirin treatment suppressed toll‑like receptor (TLR)4 and nuclear factor (NF)‑κB expression in cerebrovascular endothelial cells."	5.48	Aspirin ameliorates cerebral infarction through regulation of TLR4/NF‑κB‑mediated endoplasmic reticulum stress in mouse model. ( Cui, X; Shen, B; Sun, D; Wang, X, 2018)
"The study aimed to evaluate the clinical efficacy of the Huo Xue Hua Yu method combined with aspirin in the treatment of patients with acute cerebral infarction (ACI)."	5.41	Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A Systematic Evaluation and Meta-analysis. ( Chen, C; Liu, X; Ma, F; Tang, Q; Wen, X; Wu, Y, 2023)
"Platelet aggregation in patients with cerebral infarction receiving aspirin (100 mg/day) for at least 7 days, was measured by optical transmission aggregometry."	5.35	Variable number of tandem repeats polymorphism of platelet glycoprotein Ib alpha in Chinese people and CC genotype with aspirin sensitivity in patients with cerebral infarction. ( Cui, LY; Jin, YY; Wang, Y; Xin, XM; Yu, GZ, 2009)
"The European/Australasian stroke prevention in reversible ischaemia trial (ESPRIT) confirms that long-term administration of the combination acetylsalicylic acid and dipyridamole is more effective than acetylsalicylic acid in reducing the risk of vascular events after cerebral ischaemia of arterial origin."	5.33	[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. ( De Keyser, JH; Luijckx, GJ, 2006)
"P2Y12 receptor inhibitor plus aspirin vs aspirin given within 24 h after acute noncardioembolic ischemic stroke or TIA reduces the risk of subsequent stroke."	5.22	P2Y12 receptor inhibitor plus aspirin versus aspirin treated within 24 hours of acute noncardioembolic ischemic stroke or TIA: Meta-analysis. ( Huang, WY; Lee, M; Ovbiagele, B, 2022)
"The objective of this study was to evaluate the efficacy and safety of intravenous vinpocetine administration as part of a comprehensive treatment for acute cerebral infarction in a Chinese population."	5.22	Efficacy and Safety of Vinpocetine as Part of Treatment for Acute Cerebral Infarction: A Randomized, Open-Label, Controlled, Multicenter CAVIN (Chinese Assessment for Vinpocetine in Neurology) Trial. ( Hu, H; Huang, Y; Kong, Y; Li, C; Li, Y; Nao, J; Song, Y; Tan, L; Zhang, J; Zhang, W, 2016)
"The results of the Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS), a randomized double-blind study of sarpogrelate (selective 5-HT(2A) receptor antagonist) versus aspirin in 1510 Japanese patients, have been reported."	5.14	Sarpogrelate versus aspirin in secondary prevention of cerebral infarction: differential efficacy in diabetes? Subgroup analysis from S-ACCESS. ( Nishimaru, K; Shinohara, Y, 2009)
"Patients aged 20-79 years who had had a cerebral infarction within the previous 26 weeks were enrolled at 278 sites in Japan and allocated to receive 100 mg cilostazol twice daily or 81 mg aspirin once daily for 1-5 years."	5.14	Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial. ( Genka, C; Hamada, C; Handa, S; Katayama, Y; Kitagawa, Y; Koretsune, Y; Kusuoka, H; Matsuoka, K; Nishimaru, K; Ohashi, Y; Sawada, T; Shinohara, Y; Tanahashi, N; Tsushima, M; Uchiyama, S; Yamaguchi, T; Yamamoto, H, 2010)
"The analyses used data from the Tinzapararin in Acute Ischaemic Stroke Trial, a randomized controlled trial assessing tinzaparin (low molecular weight heparin) versus aspirin in 1484 patients with acute ischemic stroke."	5.14	Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial. ( Bath, PM; Christensen, H; De Deyn, P; England, TJ; Geeganage, C; Leys, D; Moulin, T; O'Neill, D; Ringelstein, EB; Sare, GM; Woimant, F, 2010)
"Seventy-four patients with cerebral infarction at the rehabilitation stage were assigned to two groups according to taking or not taking aspirin at hospitalization, the 30 patients in group A were administered with TXL alone and the 44 in group B with TXL combined with aspirin."	5.13	[Effect of tongxinluo capsule on platelet aggregation in patients with cerebral infarction]. ( Li, J; Liu, F; Wang, XD, 2008)
"To observe the clinical value of protoparaxotril saporlirs (PTS) combined with aspirin in the secondary prevention of cerebral infarction."	5.13	[Clinical value of protoparaxotril saporlirs combined with aspirin in the secondary prevention of cerebral infarction]. ( Liu, ZF; Xu, ZQ; Zhou, BR, 2008)
"To investigate the effects of puerarin with aspirin on the markers of damaged vascular endothelial cells, as von Willebrand factor (vWF), and thrombomodulin (TM) in patients with acute cerebral infarction (ACI)."	5.13	[Effects of puerarin with aspirin on the markers of damaged vascular endothelial cells in patients with acute cerebral infarction]. ( Ding, MP; Fen, F; Hu, HT, 2008)
"We extended the follow-up of 2473 patients from the Dutch TIA Trial (recruitment March 1986 to March 1989, all treated with aspirin; CIAO) and 186 Dutch participants of the European Atrial Fibrillation Trial (recruitment June 1988 to May 1992, 26% on anticoagulants during the trial; CIAF)."	5.13	Long-term occurrence of death and cardiovascular events in patients with transient ischaemic attack or minor ischaemic stroke: comparison between arterial and cardiac source of the index event. ( Algra, A; Gorter, JW; Kappelle, LJ; Koudstaal, PJ; van Gijn, J; van Wijk, I, 2008)
"In total, 1510 patients with recent cerebral infarction (1 week to 6 months after onset) were randomly assigned to receive either sarpogrelate (100 mg TID) or aspirin (81 mg/d)."	5.13	Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A randomized, double-blind, aspirin-controlled trial. ( Fukuuchi, Y; Gotoh, F; Handa, S; Hayashi, K; Hirai, S; Kobayashi, S; Kondo, K; Nishimaru, K; Otomo, E; Sawada, T; Shinohara, Y; Terashi, A; Tohgi, H; Uchiyama, S; Yamaguchi, T, 2008)
"Patients experiencing acute ischemic stroke or transient ischemic attack are commonly treated with clopidogrel and/or aspirin (mono- and dual-antiplatelet therapy) to minimize the risk for recurrent stroke."	5.12	Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis. ( Huang, Z; Yang, Y; Zhang, X, 2021)
"Fluctuations in urinary 11-DTB2 after cerebral infarction in blacks do not correlate with changes in aspirin doses, except perhaps when the dose changes by a factor of 4 or more."	5.11	Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. ( Bang, NU; Bruno, A; Cohen, SN; Gorelick, PB; McConnell, JP; Tietjen, GE; Wallis, RA, 2004)
"This pilot trial has not found differences between triflusal and aspirin in the prevention of vascular complications after TIA or ischemic stroke, although given the wide CI, potentially important group differences could not be ruled out."	5.11	Triflusal vs aspirin for prevention of cerebral infarction: a randomized stroke study. ( Abiusi, G; Bauso-Tosselli, L; Culebras, A; Domínguez, R; Famulari, A; Ferrari, J; Gori, H; Reich, E; Rey, R; Rotta-Escalante, R; Vila, J, 2004)
"We performed a randomized, double-blind, multicenter study to test the efficacy of triflusal (600 mg/d) versus aspirin (325 mg/d) for prevention of vascular events in patients with stroke or transient ischemic attack (Triflusal versus Aspirin in Cerebral Infarction Prevention [TACIP])."	5.10	Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial. ( Alvarez-Sabín, J; Ferro, JM; Jiménez, MD; Lago, A; Matías-Guiu, J; Melo, T; Torres, F, 2003)
"To compare the efficacy and safety of two antiplatelet regimens, ticlopidine alone (200 mg daily) and ticlopidine (100 mg daily) plus aspirin (81 mg daily), in patients with ischemic stroke from the Tokai district of Japan."	5.10	Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke. ( Ito, E; Kuzuhara, S; Nakajima, M; Takahashi, A; Uchiyama, S; Yamamoto, H, 2003)
"We determined the percentages of fibrinogen-bound and P-selectin-expressed platelets in whole blood using flow cytometry in 254 patients with various cerebral infarction subtypes, as well as in 30 age-matched controls."	5.09	Measurement of platelet fibrinogen binding and p-selectin expression by flow cytometry in patients with cerebral infarction. ( Iwata, M; Uchiyama, S; Yamazaki, M, 2001)
"We examined the effect of aspirin on the enhanced erythrocyte aggregability in 19 patients with cerebral infarction during the chronic phase."	5.08	Aspirin improves the enhanced erythrocyte aggregability in patients with cerebral infarction. ( Fukuuchi, Y; Kobari, M; Takeda, H; Tanahashi, N; Tomita, M; Yokoyama, M, 1996)
"Combination therapy with dipyridamole and aspirin reduces not only the risk of cerebrovascular ischemic events but also the risk of myocardial infarction."	5.07	Antiplatelet therapy is effective in primary prevention of myocardial infarction in patients with a previous cerebrovascular ischemic event. ( Laakso, M; Lowenthal, A; Riekkinen, PJ; Sivenius, J; Smets, P, 1993)
"In a randomized pilot study we compared the efficacy of temporary anticoagulation with intravenous heparin sodium to the efficacy of aspirin in preventing cerebral infarction in hospitalized patients with recent (less than 7 days) transient ischemic attacks (TIAs)."	5.06	A randomized trial of aspirin or heparin in hospitalized patients with recent transient ischemic attacks. A pilot study. ( Adams, HP; Banwart, KJ; Biller, J; Bruno, A; Godersky, JC; Jones, MP; Loftus, CM; Mitchell, VL, 1989)
"Previous studies have shown that various aspirin combinations might be beneficial for the treatment of acute cerebral infarction (ACI)."	5.01	Effects of six types of aspirin combination medications for treatment of acute cerebral infarction in China: A network meta-analysis. ( Fan, J; Jin, L; Sheng, J; Shi, W; Xu, L; Yuan, H; Yuan, Y; Zhou, J, 2019)
" CHIs combined with aspirin + anticoagulants + dehydrant + neuroprotectant (AADN) are believed to be effective for the treatment of acute cerebral infarction (ACI)."	4.98	Comparative efficacy of Chinese herbal injections for treating acute cerebral infarction: a network meta-analysis of randomized controlled trials. ( Cui, YY; Duan, XJ; Liu, S; Liu, XK; Tan, D; Wang, KH; Wu, JR; Zhang, B; Zhang, D; Zhang, XM, 2018)
"While previous meta-analysis have investigated the efficacy of cilostazol in the secondary prevention of ischemic stroke, they were criticized for their methodology, which confused the acute and chronic phases of stroke."	4.90	The efficacy and safety of cilostazol for the secondary prevention of ischemic stroke in acute and chronic phases in Asian population--an updated meta-analysis. ( Chen, S; Malaguit, J; Pu, J; Shi, L; Xu, L; Zhang, J, 2014)
" I have selected 4 translations in the field of vascular neurology in which I have been involved in different respects: (1) the translation of results from men to women, taking the example of aspirin which, in primary prevention, decreases the risk of myocardial infarction in men and the risk of cerebral infarction in women, the reason for this sex difference being so far unknown; (2) the 'inverse translational research', from bedside to bench, taking the example of the disease we have identified--CADASIL--and showing how the study of one patient and his family led to the identification of a gene, Notch3, so far unknown in humans and to the discovery of its key role in the physiology of vascular smooth muscle cells; (3) the translation from individual case reports to multidisciplinary trials taking the example of hemicraniectomy in malignant cerebral infarction and emphasizing the interest in such rare and severe conditions of pooling and reporting the results of randomized clinical trials before the results of individual trials, and (4) the translation from research to practice, emphasizing not the well-known 'evidence to practice gap' but the slippery slope of 'lack of evidence to overpractice', taking the example of patent foramen ovale closure in migraine."	4.84	Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008. ( Bousser, MG, 2008)
"At the acute phase of cerebral infarction, two recent large studies found that the use of aspirin reduces both mortality and the risk of the recurrence of stroke."	4.80	[Aspirin and cerebral ischemic accidents]. ( Bousser, MG; Crassard, I; Niclot, P, 2000)
"Long-term use of aspirin and severity of cerebral infarction are risk factors for gastrointestinal bleeding in cerebral infarction patients receiving dual antiplatelet therapy."	4.31	Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy. ( Huang, J; Liao, F; Shu, X; Tang, J, 2023)
" Patients aged 80 years or older who received monotherapy with clopidogrel or aspirin following hospitalization for primary acute ischemic stroke between January 1, 2009, and December 31, 2018, were included."	4.12	Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke. ( Huang, HY; Katz, AJ; Lin, FJ; Lin, SY; Sheu, JJ; Wang, CC; Wu, CH, 2022)
" Here, we report the case of an 82-year-old Japanese woman with normal renal function who developed multiple cerebral infarctions due to CAT that grew rapidly, associated with inflammation from an antecedent infection, and diminished rapidly by detachment of fibrin on the mass surface and antithrombotic drugs."	4.12	Multiple cerebral infarctions due to calcified amorphous tumor growing rapidly from an antecedent infection and decreasing rapidly by detachment of fibrin and antithrombotic drugs: a case report. ( Doyu, M; Ito, H; Kimura, M; Matsuyama, K; Niwa, JI, 2022)
"We investigated (1) the associations of pre-stroke aspirin use with thrombus burden, infarct volume, hemorrhagic transformation, early neurological deterioration (END), and functional outcome, and (2) whether stroke subtypes modify these associations in first-ever ischemic stroke."	4.02	Relation of Pre-Stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes. ( Bae, HJ; Cha, JK; Cho, YJ; Choi, KH; Han, MK; Hong, KS; Jeong, SW; Kang, K; Kim, BJ; Kim, DE; Kim, DH; Kim, JG; Kim, JT; Lee, BC; Lee, J; Lee, KB; Lee, SJ; Nahrendorf, M; Oh, MS; Park, HK; Park, JM; Park, MS; Park, SS; Park, TH; Ryu, WS; Schellingerhout, D; Yu, KH, 2021)
"To investigate the association of aspirin resistance (AR) with the plasma 4-hydroxynonenal (4-HNE) level and its impact on recurrent cerebral infarction (CI) in patients with acute cerebral infarction (ACI) who were receiving aspirin therapy."	3.96	Association of aspirin resistance with 4-hydroxynonenal and its impact on recurrent cerebral infarction in patients with acute cerebral infarction. ( Feng, J; Guo, J; Guo, Y; Wang, J, 2020)
"Subsequent to the onset of acute cerebral infarction, the patient was immediately treated with oral aspirin, atorvastatin, and intravenous butylphthalide."	3.96	Acute bilateral cerebral infarction in the presence of neuromyelitis optica spectrum disorder: A case report. ( Gao, YL; Guo, JJ; Wang, M; Wang, ZY; Yu, XF, 2020)
"Atorvastatin and aspirin have been used in treating different forms of epilepsy."	3.96	Effects of atorvastatin and aspirin on post-stroke epilepsy and usage of levetiracetam. ( Ding, Y; Feng, X; Lin, W; Zhao, T; Zhou, C, 2020)
" This man was promptly treated with aspirin 300 mg one time per day, as per the stroke pathway."	3.91	Bilateral paramedian pontine infarcts: a rare cause of bilateral horizontal gaze palsy. ( Bhandari, M; Chernov, D; Hassan, F; Karavassilis, ME, 2019)
"BACKGROUND To investigate the combination of beraprost sodium (BPS) and aspirin in the treatment of acute ischemic stroke (AIS)."	3.85	Beneficial Effect of Beraprost Sodium Plus Aspirin in the Treatment of Acute Ischemic Stroke. ( Chen, S; Chen, W; He, W; Li, S; Wei, D; Xie, S, 2017)
"To explore the correlation between the recurrence of cerebral infarction and aspirin resistance (AR)/Chinese medical (CM) constitutions."	3.81	[Recurrence of Cerebral Infarction Associated Aspirin Resistance or Chinese Medical Constitutions: a Correlation Study]. ( Li, YH; Lu, QA; Wang, DX; Wang, XC; Yu, LH; Zong, SJ, 2015)
"Japanese guidelines recommend aspirin 160-300 mg/day, starting within 48 h, for patients with acute cerebral infarction."	3.80	Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. ( Inuyama, L; Mizuno, O; Sakaguchi, T; Takahashi, S; Yamada, T, 2014)
"To investigate the relationship between aspirin resistance and clinical and neuroimaging measures of stroke severity in acute stroke patients."	3.79	Association of aspirin resistance with increased stroke severity and infarct size. ( Churilov, L; Colley, RE; Davis, SM; Goh, C; Yan, B; Zheng, AS, 2013)
"Treatment with cilostazol for 7 days before ischemia significantly suppressed the risk and severity of cerebral hemorrhage after injection of tissue-type plasminogen activator, although treatment with aspirin had no such protective effect compared with nontreated mice."	3.78	Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model. ( Kasahara, Y; Matsuyama, T; Nakagomi, T; Stern, D; Taguchi, A, 2012)
"Co-prescribed aspirin and dipyridamole are more effective than aspirin alone following cerebral infarction; however, patients may struggle with this more complex regimen."	3.78	Persistence, adherence and outcomes with antiplatelet regimens following cerebral infarction in the Tayside Stroke Cohort. ( Doney, AS; Flynn, RW; MacDonald, TM; MacWalter, RS; Murray, GD, 2012)
"9 years) with confirmed diagnoses of cerebral infarction and PAS, treated with anticoagulants (n = 54) or aspirin (n = 38) were retrospectively analyzed."	3.77	[Aspirin versus anticoagulation in young patients with cerebral infarction secondary to primary antiphospholipid syndrome]. ( Arauz, A; Artigas, C; Barinagarrementeria, F; Cantu-Brito, C; Hernandez, B; Marquez, JM; Merlos, M; Perez, A; Roa, LF, 2011)
"Patients who have had a recent transient ischemic attack (TIA) are at high risk for subsequent stroke."	3.77	Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly. ( Adams, HP; Gordon, DL, 1991)
"Endoscopy reveals low-dose aspirin-induced gastroduodenal injuries in patients with cerebral infarction."	3.76	Investigation of gastroduodenal mucosal injuries caused by low-dose aspirin therapy in patients with cerebral infarction. ( Kato, M; Nema, H, 2010)
"We report a case in which hemorrhage occurred in an asymptomatic falx meningioma known beforehand, after the internal use of low-dose aspirin for 16 months."	3.74	Hemorrhage from a falx meningioma after internal use of low-dose aspirin. ( Miyazawa, T; Shima, K; Toyooka, T; Uozumi, Y, 2008)
"A Markov model was developed to calculate the health outcomes and associated costs for 65-year-old patients with cerebral infarction who were treated with 200 mg/day cilostazol or 81 mg/day aspirin."	3.73	Pharmacoeconomic analysis of cilostazol for the secondary prevention of cerebral infarction. ( Inoue, T; Kobayashi, M; Uchiyama, S; Uetsuka, Y, 2006)
"We evaluated both the effect of aspirin treatment (81 mg/day) on serum Lp(a) concentrations and the correlation between the degree of reduction in serum Lp(a) and the type of apo(a) isoform in 70 patients with coronary artery disease or cerebral infarction."	3.71	Effect of aspirin treatment on serum concentrations of lipoprotein(a) in patients with atherosclerotic diseases. ( Aihara, K; Akaike, M; Azuma, H; Hayashi, I; Iuchi, T; Kagawa, A; Kanagawa, Y; Matsumoto, K; Matsumoto, T; Nishiuchi, T; Takamori, N; Tamura, K; Yoshida, T, 2002)
"This follow-up study was designed to evaluate whether the use of aspirin either before or after aneurysm rupture affects the occurrence of delayed cerebral ischemia."	3.69	Aspirin and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Juvela, S, 1995)
"Elevated levels of plasma fibrinogen are a risk factor for cerebral infarction."	3.69	Effect of plasma fibrinogen concentration on the inhibition of platelet aggregation after ticlopidine compared with aspirin. ( Kashiwaya, M; Takahashi, H; Tohgi, H; Watanabe, K, 1994)
"Our study demonstrates high prevalence of aCL in children who suffer acute cerebral infarction and our results suggest aspirin may be effective therapy to prevent recurrences."	3.69	Cerebral infarction and antiphospholipid syndrome in children. ( Baca, V; Garcia-Ramirez, R; Lavalle, C; Marquez-Enriquez, L; Martinez, I; Ramirez-Lacayo, M, 1996)
"Thromboxane A2 (TXA2) biosynthesis was studied in healthy subjects, patients with chronic cerebral infarction, patients under chronic aspirin treatment and patients with atrial fibrillation."	3.68	Urinary 11-dehydro-thromboxane B2: a quantitative index of platelet activation in cerebral infarction. ( Hayashi, Y; Nakahama, H; Nakanishi, T; Shimizu, S; Sugita, M; Takiguchi, A; Uyama, O; Yamamoto, S, 1992)
"During a 1-year period, we prospectively studied the mechanism and severity of stroke in 47 patients sustaining a cerebral infarction while taking aspirin."	3.68	Mechanism of stroke in patients taking aspirin. ( Chimowitz, MI; Furlan, AJ; Nayak, S; Sila, CA, 1990)
"The difference in the effectiveness of aspirin for the prevention of stroke and secondary prevention of myocardial infarction was discussed on the basis of inhibition of platelet aggregation."	3.67	Experimental basis of platelet aggregation inhibition by acetylsalicylic acid. ( Begent, NA; Born, GV; Görög, P, 1984)
"Data from the medical treatment group of the Aspirin in TIA study were reviewed, and prospective analysis of patients with asymptomatic bruits was performed to see whether carotid stenosis (0 to 49% or 50 to 99%) or ulceration produced an increased risk of ipsilateral TIA or infarct."	3.67	The significance of carotid stenosis or ulceration. ( Bigelow, RH; Fields, WS; Grotta, JC; Hankins, L; Hu, H, 1984)
"The effects of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3, 4-dihydro-2(1H)-quinolinone (cilostazol, OPC-13013), acetylsalicylic acid (ASA) and ifenprodil on experimentally induced cerebral infarction were studied in anesthetized rabbits."	3.67	Effect of cilostazol on experimental cerebral infarction in rabbits. ( Kimura, Y; Nakase, H; Watanabe, K, 1986)
"Keyword: antiplatelet therapy, acute ischemic stroke, secondary prevention, transient ischemic attack."	3.01	Clinical Updates on Antiplatelet Therapy for Secondary Prevention in Acute Ischemic Stroke. ( Chang, YM; Lee, TL; Sung, PS, 2023)
"The coexistence of TS and acute cerebral infarction is rare."	2.82	Thyroid storm complicated by corpus callosum infarction in a young patient: A case report and literature review. ( Cai, Y; Gang, X; Li, C; Liu, X; Ren, L; Wang, G, 2022)
"The 40 patients with cerebral infarction were randomly divided into aspirin-treated group (20 cases) and clopidogrel-treated group (20 cases) scandinavian neurological stroke score (SNSS), plasma sP-sel, serum CRP, PAR and PLA were observed before and after the treatment."	2.73	[The changes and effects of antiplatelet agents on platelet-leukocyte aggregation in patients with acute cerebral infarction]. ( Cao, YJ; Feng, P; Liu, CF; Wang, YM, 2007)
"Eptifibatide was not associated with an increase in intracranial hemorrhage, and no significant effect on nonhemorrhagic stroke was observed."	2.69	Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. ( Alberts, MJ; Berdan, LG; Califf, RM; Deckers, J; Graffagnino, C; Granger, CB; Harrington, RA; Laskowitz, DT; Lincoff, AM; MacAulay, CM; Mahaffey, KW; Miller, JM; Simoons, ML; Sloan, MA; Topol, EJ, 1999)
"Initially, transient ischemic attack or cerebral infarction occurring in the distribution of the study artery and any transient ischemic attack, stroke, or death occurring in the perioperative period."	2.68	Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. ( , 1995)
"In addition, 6 transient ischemic attacks and 3 myocardial infarctions could be directly linked to CEA, for a total CEA event rate of 2."	2.68	An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. ACAS Investigators. Asymptomatic Carotid Atherosclerosis Study. ( Broderick, JP; Cohen, SN; Dempsey, RJ; Ernst, CB; Hosking, JD; Moore, WS; Robertson, JT; Toole, JF; Young, B, 1996)
"The subjects were 75 patients with cerebral ischemia and 26 control subjects."	2.67	Shear-induced platelet aggregation in cerebral ischemia. ( Fukuyama, M; Handa, M; Ikeda, Y; Itagaki, I; Maruyama, S; Uchiyama, S; Yamazaki, M, 1994)
"The number of fatal and non fatal cerebral infarction was 31 in the P group, 17 in the ASA group, and 18 in the ASA + D group."	2.65	[The A.I.C.L.A. controlled cooperative trial. Secondary prevention of cerebral ischemic accidents due to atherosclerosis by aspirin and dipyridamole. 3: Results]. ( Bousser, MG; Eschwege, E; Haguenau, M; Lefauconnier, JM; Thibult, N; Touboul, D; Touboul, PJ, 1983)
"Of the 5 cerebral infarcts, 4 occurred in the control group, 3 patients died."	2.65	[The treatment of transitory ischemic attacks with acetylsalicylic acid: results of a double-blind-study (author's transl)]. ( Dorndorf, W; Loew, D; Reuther, R, 1980)
" As for intracranial hemorrhage (ICH), stroke recurrence, and adverse event (AE) rate, there were no significant differences of efficacy among 7 drug therapies."	2.58	Aspirin plus dipyridamole has the highest surface under the cumulative ranking curves (SUCRA) values in terms of mortality, intracranial hemorrhage, and adverse event rate among 7 drug therapies in the treatment of cerebral infarction. ( Liu, X; Zhang, JJ, 2018)
"In the chronic stage of cerebral infarction, monotherapy (aspirin, clopidogrel or cilostazol) is recommended."	2.50	[Antiplatelet therapy for secondary prevention of cerebral infarction]. ( Tanahashi, N, 2014)
" In addition, the discussion here reviews select acute ischemic stroke intravenous thrombolytic studies, such as the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study and European Cooperative Acute Stroke Studies, select neuroprotectant and endovascular clot retrieval device studies, and large cooperative databases, such as the Virtual International Stroke Trials Archive and Safe Implementation of Treatment in Stroke-International Stroke Thrombolysis Registry, to explore relationships between baseline stroke severity and other possible factors associated with efficacy and safety outcomes."	2.48	How baseline severity affects efficacy and safety outcomes in acute ischemic stroke intervention trials. ( Gorelick, PB, 2012)
"Thrombosis has a proinflammatory component whereby biologically active substances are synthesized by different cell types that could not individually synthesize the metabolite(s)."	2.43	Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection. ( Broekman, MJ; Drosopoulos, JH; Islam, N; Levi, R; Marcus, AJ; Olson, KE; Pinsky, DJ, 2005)
"Susac's syndrome is an extremely rare clinical manifestation characterized by the triad of fluctuating sensorineural hearing loss, sudden visual loss and encephalopathy."	2.41	[Susac syndrome as a cause of sensorineural hearing loss]. ( Albaladejo Devis, I; Cubillana Herrero, JD; Jiménez Cervantes-Nicolás, JA; Minguez Merlos, N; Rodríguez González-Herrero, B; Soler Valcárcel, A, 2002)
"Aspirin was used as control in all trials."	2.41	Anticoagulants versus antiplatelet agents for acute ischaemic stroke. ( Berge, E; Sandercock, P, 2002)
"6 studies with a placebo-controlled, double blind, randomized protocol on the effect of acetylsalicylic acid (ASA) in a dosage of higher than 100 mg/day have been published."	2.39	[High dosage acetylsalicylic acid administration for prevention of acute cerebral ischemia]. ( Hartmann, A, 1995)
" There is disagreement over the optimal dosage to prevent a stroke: earlier studies considered > or = 975 mg ASS per day, sometimes in combination with other substances, while more recently, lower dosages of about 300 mg per day or even as low as < or = 100 mg per day have been proposed."	2.39	[Aspirin dosage for prevention of cerebral infarct: arguments for low dosage]. ( Hennerici, MG; Meairs, S, 1995)
"Paroxysmal atrial fibrillation is associated with a lower risk of thromboembolic complications than chronic atrial fibrillation."	2.38	Thromboembolic complications in atrial fibrillation. ( Petersen, P, 1990)
"The results showed that the patients of cerebral infarction treated with Danshen Chuanxiongqin Injection were mainly elderly males, and often complicated with hypertension, coronary heart disease, diabetes and other basic diseases."	1.56	[Study on clinical characteristics of Danshen Chuanxiongqin Injection in treatment of cerebral infarction in real world]. ( Gao, Y; Guo, XC; Sun, LX; Xie, YM; Xu, HY; Zhuang, Y, 2020)
"Heat stroke is a life-threatening disease characterized by hyperthermia and neurological dysfunction."	1.56	Unusual manifestation of heat stroke: Isolated trochlear nerve palsy. ( Han, S; Kim, BK; Yum, KS, 2020)
"Cerebral vasospasm was more often only mild and rates of cerebral infarctions were lower in the OTA group but not on a significant level."	1.51	Pain medication at ictus of subarachnoid hemorrhage-the influence of one-time acetylsalicylic acid usage on bleeding pattern, treatment course, and outcome: a matched pair analysis. ( Brawanski, N; Bruder, M; Kashefiolasl, S; Keil, F; Konczalla, J; Seifert, V; Won, SY, 2019)
"A part of familial Hirschsprung disease has genetic factors in common with cerebrovascular disease."	1.51	A Unique Recurrent Stroke Case due to Bilateral Vertebral Artery Dissection with Familial Hirschsprung Disease. ( Abe, K; Hishikawa, N; Ohta, Y; Sasaki, R; Sato, K; Takemoto, M; Yamashita, T, 2019)
"Aspirin treatment suppressed toll‑like receptor (TLR)4 and nuclear factor (NF)‑κB expression in cerebrovascular endothelial cells."	1.48	Aspirin ameliorates cerebral infarction through regulation of TLR4/NF‑κB‑mediated endoplasmic reticulum stress in mouse model. ( Cui, X; Shen, B; Sun, D; Wang, X, 2018)
"Seizures are rare manifestation of thalamic disorder."	1.46	Unilateral Thalamic Infarct Presenting as a Convulsive Seizure. ( Brohi, H; Kumar, R; Mughul, A, 2017)
"Procedure-related thromboembolism is a major limitation of coil embolization, but the relationship between thromboembolic infarction and antiplatelet resistance is poorly understood."	1.43	Association between Postprocedural Infarction and Antiplatelet Drug Resistance after Coiling for Unruptured Intracranial Aneurysms. ( Hong, SC; Jeon, P; Jo, KI; Kim, JS; Kim, KH; Kim, MS; Yeon, JY, 2016)
"An incidence as high as 60% of silent cerebral infarcts (SCI) has been demonstrated by brain Magnetic Resonance Imaging (MRI) studies in beta thalassemia intermedia (TI)."	1.43	High incidence of silent cerebral infarcts in adult patients with beta thalassemia major. ( Cohen, M; Inbar, E; Pazgal, I; Shpilberg, O; Stark, P, 2016)
"He had been treated for lung cancer by chemotherapy and irradiation 3 years earlier."	1.40	[Case of cardiac tamponade during the treatment of acute cerebral infarction]. ( Nagasawa, H; Ono, H; Tanaka, H; Yamakawa, T, 2014)
" A loading dosage of aspirin (500 mg) and/or clopidogrel (300 mg) was given 24 hours before the procedure to patients naïve to antiplatelet agents, whereas the usual dosage (aspirin 100 mg and clopidogrel 75 mg) was continued for patients who had previously been taking these agents for more than a week."	1.40	Association between silent embolic cerebral infarction and continuous increase of P2Y12 reaction units after neurovascular stenting. ( Jung, JM; Kang, DW; Kim, BJ; Kim, JS; Kwon, JY; Kwon, SU; Lee, DH, 2014)
" The injection is administered intravenously,with most patients receiving a dosage of 15-20 mL per dose for between 1 and 14 days."	1.40	[Analysis of clinical use of shuxuening injection in treatment of cerebral infarction based on real world]. ( Luo, YH; Wang, YY; Xie, YM; Yang, W; You, L; Zhuang, Y, 2014)
"Patients with cerebral infarction crowd using parenterally administered Shuxuetong were a mostly elderly population, with an average age of 66."	1.39	[Clinical outcomes of parenterally administered shuxuetong--analysis of hospital information system data]. ( Xie, YM; Yang, H; Yang, W; Zhang, H; Zhi, YJ; Zhuang, Y, 2013)
"Cerebral infarction is a major cause of death or decreasing activities of daily living."	1.38	Clinical and pathological improvement in stroke-prone spontaneous hypertensive rats related to the pleiotropic effect of cilostazol. ( Abe, K; Deguchi, K; Kawai, H; Kurata, T; Ohta, Y; Omote, Y; Tian, F; Yamashita, T, 2012)
"Aspirin (30 mg/kg) treatment also reduced platelet aggregation."	1.35	Aspirin attenuates cerebral ischemic injury in diabetic rats. ( Fu, FH; Han, B; Wang, T; Yu, X; Zhang, LM; Zhu, M, 2009)
"He was diagnosed as idiopathic cerebral infarction."	1.35	[Recurrent idiopathic cerebral infarction in a 5-year-old boy, with emphasis on the importance of platelet aggregation analysis for appropriate selection of anti-platelet drugs]. ( Ikegami, M; Matsuda, S; Miyashita, Y; Obara, S; Shimizu, M; Sugiyama, N; Takagi, S; Takizawa, S; Yokoyama, J, 2009)
"Platelet aggregation in patients with cerebral infarction receiving aspirin (100 mg/day) for at least 7 days, was measured by optical transmission aggregometry."	1.35	Variable number of tandem repeats polymorphism of platelet glycoprotein Ib alpha in Chinese people and CC genotype with aspirin sensitivity in patients with cerebral infarction. ( Cui, LY; Jin, YY; Wang, Y; Xin, XM; Yu, GZ, 2009)
"We present familial Moyamoya disease in two European children and emphasize the importance of familial factors in the pathogenesis of this disease and its appearance not only in Asians but in the Western population as well."	1.34	Familial Moyamoya disease in two European children. ( Bazigou-Fotopoulou, H; Ikeda, H; Papavasiliou, A, 2007)
"He suffered immediate loss of consciousness but recovered three days later with right-sided hemiplegia and complete aphasia."	1.34	Carotid occlusion and cerebral infarction from camel bite: case report. ( Laseini, A; Mahmud, MR; Nasiru, JI; Saidu, SA; Shehu, BB, 2007)
"Cerebral ischemia was mechanically induced by 2-hour occlusion of the left middle cerebral artery (MCA) using an intraluminal filament followed by 24-hour reperfusion."	1.33	Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. ( Hong, KW; Lee, JH; Lee, WS; Park, SY, 2005)
"Treatment with aspirin and ceftriaxone followed by trimethoprim-sulfamethoxazole resulted in a good neurological recovery and complete remission of the malabsorption syndrome."	1.33	A patient with cerebral Whipple's disease and a stroke-like syndrome. ( De Simone, C; Famularo, G; Minisola, G, 2005)
"The dorso-lateral medullary syndrome (Wallenberg's syndrome) is produced by infarction of a wedge of lateral medulla posterior to the inferior olivary nucleus and is usually caused by vertebral artery occlusion."	1.33	The clinical variability of Wallenberg's syndrome. The anatomical correlate of ipsilateral axial lateropulsion. ( Nowak, DA; Topka, HR, 2006)
"A 65-year-old woman experienced sudden positional vertigo with rightward, horizontal nystagmus that resolved within days."	1.33	Rotational vertigo associated with parietal cortical infarction. ( Fujioka, S; Hashimoto, Y; Hirano, T; Inatomi, Y; Naganuma, M; Uchino, M; Yonehara, T, 2006)
"The European/Australasian stroke prevention in reversible ischaemia trial (ESPRIT) confirms that long-term administration of the combination acetylsalicylic acid and dipyridamole is more effective than acetylsalicylic acid in reducing the risk of vascular events after cerebral ischaemia of arterial origin."	1.33	[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. ( De Keyser, JH; Luijckx, GJ, 2006)
"A splenic infarction is a complication pointing towards an underlying serious disorder."	1.32	[Diagnosis of acute splenic infarction by echo-signal-enhanced ultrasound]. ( Fölsch, UR; Seeger, M, 2004)
"The findings were consistent with a cerebral infarct (stroke)."	1.32	Diagnosis and treatment of a cerebral infarct in a chimpanzee (Pan troglodytes). ( Carpenter, JW; Fish, PH; Kraft, S, 2004)
"Most patients with PAD die of either heart attacks or strokes and they die of the former conditions far earlier than controls."	1.32	[Antiplatelet therapy in patients with peripheral arterial disease (PAD)]. ( Diehm, C; Huber, R; Lawall, H, 2004)
"Moyamoya disease is a cerebrovascular disease with progressive occlusion of both internal carotid arteries and of their branches and formation of a new vascular network at the base of the brain."	1.31	Moyamoya syndrome with protein S deficiency. ( Akgün, D; Aslan, B; Gürer, YY; Senbil, N; YiLmaz, S, 2000)
"We present a case of antiphospholipid antibody syndrome (APS) with repeated transient ischemic attacks (TIAs)."	1.31	Technetium-99m-ECD SPECT in antiphospholipid antibody syndrome: a drastic improvement in brain perfusion by antiplatelet therapy. ( Kudo, S; Kuroda, Y; Matsui, M; Tokumaru, S; Uchino, A; Yoshikai, T, 2001)
"Aspirin was usually chosen after initial brain ischemia."	1.29	Patent foramen ovale and brain infarct. Echocardiographic predictors, recurrence, and prevention. ( Furlan, AJ; Hanna, JP; Sila, CA; Stewart, WJ; Sun, JP; Tan, M, 1994)
"Most of cerebral infarctions were observed in the hemisphere, ipsilateral to the irradiated carotid artery."	1.29	Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits. ( Fujimura, M; Mikashima, H, 1993)
"At autopsy, cerebral amyloid angiopathy (CAA) was found."	1.29	Fatal hemorrhage during anticoagulation of cardioembolic infarction: role of cerebral amyloid angiopathy. ( Bogousslavsky, J; Janzer, R; Melo, TP; Regli, F, 1993)
"The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model."	1.28	Dose-response of rt-PA and its combination with aspirin in a rat embolic stroke model. ( Boysen, G; Overgaard, K; Pedersen, H; Sereghy, T, 1992)
"Eight patients, 3 with systemic lupus erythematosus (SLE) or "SLE-like" disease, 1 with sarcoidosis, and 4 with no connective tissue disease had transient ischemic attacks (TIA) or cerebral infarctions associated with high levels of anticardiolipin antibodies (ACA)."	1.28	Cerebral ischemia associated with anticardiolipin antibodies. ( Ernerudh, J; Lindström, F; Olsson, JE; Vrethem, M, 1992)
"Aspirin treatment failed in 21 patients with severe carotid stenosis (greater than 75% stenosis)."	1.28	Patterns of failure of aspirin treatment in symptomatic atherosclerotic carotid artery disease. ( Chen, TL; Chyatte, D, 1990)
"Cerebral involvement associated with juvenile rheumatoid arthritis is rare."	1.27	Cerebral infarction in juvenile rheumatoid arthritis. ( Chand, RP; Chuah, SP; Gururaj, AK, 1988)
"A patient is reported who sustained a cerebral infarction from carotid artery disease and was treated with aspirin."	1.27	Aspirin, anticoagulants, and hemorrhagic conversion of ischemic infarction: hypothesis and implications. ( Fisher, M, 1986)
"Anticoagulant treatment after cerebral infarcts is still debated due to the imperfectly evaluated risk of hemorrhagic transformation."	1.27	[Late hemorrhagic transformation of cerebellar infarction under anticoagulant treatment]. ( Cambier, J; Charlier, P; Masson, C; Masson, M, 1985)

Research

Studies (299)

Authors

Clinical Trials (13)

Trial Overview

Trial Outcomes

Adjudicated Composite of Non-fatal Stroke, Non-fatal Myocardial Infarction, or Cardiovascular Death

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (12.37)	18.7374
1990's	71 (23.75)	18.2507
2000's	100 (33.44)	29.6817
2010's	61 (20.40)	24.3611
2020's	30 (10.03)	2.80

Authors	Studies
Ryu, WS	2
Schellingerhout, D	2
Hong, KS	1
Jeong, SW	1
Kim, BJ	3
Kim, JT	1
Lee, KB	1
Park, TH	1
Park, SS	1
Park, JM	1
Kang, K	1
Cho, YJ	1
Park, HK	1
Lee, BC	1
Yu, KH	1
Oh, MS	1
Lee, SJ	1
Kim, JG	1
Cha, JK	1
Kim, DH	1
Lee, J	2
Han, MK	1
Park, MS	1
Choi, KH	1
Nahrendorf, M	2
Bae, HJ	1
Kim, DE	2
Yang, Y	2
Huang, Z	1
Zhang, X	2
Rostanski, SK	1
Kvernland, A	1
Liberman, AL	1
de Havenon, A	1
Henninger, N	1
Mac Grory, B	1
Kim, AS	1
Easton, JD	3
Johnston, SC	3
Yaghi, S	1
Del Brutto, VJ	1
Diener, HC	6
Granger, CB	2
Cronin, L	1
Kleine, E	1
Grauer, C	1
Brueckmann, M	1
Toyoda, K	3
Schellinger, PD	1
Lyrer, P	1
Molina, CA	1
Chutinet, A	1
Bladin, CF	1
Estol, CJ	1
Sacco, RL	2
Uchiyama, S	10
Okamura, S	1
Omae, K	1
Hoshino, H	1
Kimura, K	2
Kitagawa, K	1
Minematsu, K	2
Yamaguchi, T	4
Huang, HY	1
Lin, SY	1
Katz, AJ	1
Sheu, JJ	1
Lin, FJ	1
Wang, CC	1
Wu, CH	1
Cai, Y	1
Ren, L	1
Liu, X	3
Li, C	2
Gang, X	1
Wang, G	1
Runge, A	1
Brazel, D	1
Pakbaz, Z	1
Kimura, M	1
Niwa, JI	1
Ito, H	1
Matsuyama, K	1
Doyu, M	1
Chang, R	1
Zhou, W	1
Ye, Y	1
Liu, Y	1
Wu, J	2
Suo, Y	2
Pan, Y	2
Chen, W	4
Jing, J	4
Yan, H	2
Li, H	4
Liu, L	4
Zhao, X	4
Wang, Y	9
Meng, X	4
Wang, A	2
Tian, X	1
Zuo, Y	1
Bath, PM	3
Xie, X	2
Lin, J	1
Li, Z	2
Jiang, Y	2
Xu, J	1
Wang, F	1
Cao, M	1
Li, J	2
Xu, Q	1
Huang, J	1
Liao, F	1
Tang, J	1
Shu, X	1
Chen, C	1
Ma, F	1
Wen, X	1
Tang, Q	1
Wu, Y	1
Lee, TL	1
Chang, YM	1
Sung, PS	1
Brorson, JR	1
Giurcanu, M	1
Prabhakaran, S	1
Bykov, VV	1
Bykova, AV	1
Motov, VS	1
Larchenko, VV	1
Chernysheva, GA	1
Smol'yakova, VI	1
Aliev, OI	1
Khazanov, VA	1
Vengerovskii, AI	1
Udut, VV	1
Chernov, D	1
Karavassilis, ME	1
Hassan, F	1
Bhandari, M	1
Hankey, GJ	1
Guo, J	1
Wang, J	1
Guo, Y	2
Feng, J	1
Alay, H	1
Can, FK	1
Gözgeç, E	1
Guo, XC	1
Gao, Y	1
Xie, YM	3
Sun, LX	1
Xu, HY	1
Zhuang, Y	3
Ye, F	1
Bao, GS	1
Xu, HS	1
Deng, PP	1
Han, S	1
Kim, BK	1
Yum, KS	1
Wang, ZY	1
Wang, M	1
Guo, JJ	1
Gao, YL	1
Yu, XF	1
Kim, J	1
Jang, HJ	1
Lee, SK	1
Kim, H	1
Kim, YD	1
Lee, KY	1
Choi, HY	1
Cho, HJ	1
Jang, SS	1
Jeon, S	1
Kwon, IC	1
Kim, K	1
Choi, S	1
Zhao, T	1
Ding, Y	1
Feng, X	1
Zhou, C	1
Lin, W	1
Gao, M	1
Lei, J	1
Patel, S	1
Sanborn, D	1
Issa, M	1
Huang, WY	1
Ovbiagele, B	1
Lee, M	1
Hewett, KM	1
Lorenzetti, B	1
Jackson, BF	1
Chen, S	2
Xie, S	1
He, W	1
Wei, D	1
Li, S	1
Kumar, R	1
Brohi, H	1
Mughul, A	1
Wang, X	1
Shen, B	1
Sun, D	1
Cui, X	1
Lin, ZJ	1
Qiu, HY	1
Tong, XX	1
Han, MF	1
Yang, CS	1
Lin, KH	1
Li, X	1
Bruder, M	2
Won, SY	2
Wagner, M	1
Brawanski, N	2
Dinc, N	1
Kashefiolasl, S	2
Seifert, V	2
Konczalla, J	2
Saji, N	1
Tone, S	1
Murotani, K	1
Yagita, Y	1
Sakurai, T	1
Khardenavis, V	1
Karthik, DK	1
Kulkarni, S	1
Deshpande, A	1
Zhang, JJ	1
Liu, S	1
Wu, JR	1
Zhang, D	1
Wang, KH	1
Zhang, B	1
Zhang, XM	1
Tan, D	1
Duan, XJ	1
Cui, YY	1
Liu, XK	1
Shabbir, SH	1
Nadeem, F	1
Labovitz, D	1
Keil, F	1
Jin, L	1
Zhou, J	1
Shi, W	1
Xu, L	2
Sheng, J	1
Fan, J	1
Yuan, Y	1
Yuan, H	1
Rose, EAC	1
Sherwin, T	1
Sato, K	1
Sasaki, R	1
Ohta, Y	2
Takemoto, M	1
Hishikawa, N	1
Yamashita, T	3
Abe, K	2
Vinnakota, S	1
Sharain, K	1
McBane, RD	1
Tomizawa, Y	1
Tanaka, R	1
Sekiguchi, K	1
Oji, Y	1
Tanaka, Y	1
Yamashiro, K	1
Hattori, N	1
Qu, H	1
Zhang, YQ	1
Zhou, MM	1
Zhao, XY	1
Shaikh, Q	1
Kamal, AK	1
He, MS	1
Sheu, MM	1
Huang, ZL	1
Tsai, CH	1
Tsai, RK	1
Takahashi, S	2
Mizuno, O	1
Sakaguchi, T	1
Yamada, T	1
Inuyama, L	1
Zhi, YJ	1
Zhang, H	1
Yang, W	2
Yang, H	1
Nagasawa, H	1
Ono, H	1
Tanaka, H	1
Yamakawa, T	1
Kwon, JY	1
Jung, JM	1
Lee, DH	2
Kang, DW	2
Kim, JS	3
Kwon, SU	3
Tanahashi, N	4
Shi, L	1
Pu, J	1
Malaguit, J	1
Zhang, J	3
Luo, YH	1
Wang, YY	1
You, L	1
Tsuda, H	1
Fujita, T	1
Maruyama, K	1
Ishihara, M	1
Chen, JJ	1
Chang, HF	1
Liu, CY	1
Chen, DL	1
Yu, LH	1
Wang, DX	1
Li, YH	1
Lu, QA	1
Zong, SJ	1
Wang, XC	1
Wilson, LK	1
Pearce, LA	1
Arauz, A	2
Anderson, DC	2
Tapia, J	1
Bazan, C	1
Benavente, OR	1
Field, TS	1
Kim, MS	1
Jo, KI	1
Yeon, JY	1
Kim, KH	1
Jeon, P	1
Hong, SC	1
Zhang, W	1
Huang, Y	1
Li, Y	1
Tan, L	1
Nao, J	1
Hu, H	2
Kong, Y	1
Song, Y	1
Pazgal, I	1
Inbar, E	1
Cohen, M	1
Shpilberg, O	1
Stark, P	1
Koziol, K	1
Van der Merwe, V	1
Yakiwchuk, E	1
Kosar, L	1
Liu, F	1
Wang, XD	1
Einecke, D	2
Bousser, MG	4
Miyazawa, T	1
Uozumi, Y	1
Toyooka, T	1
Shima, K	1
Wang, T	1
Fu, FH	1
Han, B	1
Zhu, M	1
Yu, X	1
Zhang, LM	1
Zhou, BR	1
Xu, ZQ	1
Liu, ZF	1
Claes, C	1
Mittendorf, T	1
Grond, M	3
von der Schulenburg, JM	1
Sugiyama, N	1
Matsuda, S	1
Shimizu, M	1
Obara, S	1
Ikegami, M	1
Yokoyama, J	1
Miyashita, Y	1
Takizawa, S	1
Takagi, S	1
Jin, YY	1
Yu, GZ	1
Cui, LY	1
Xin, XM	1
Hu, HT	1
Fen, F	1
Ding, MP	1
Ramphul, N	1
Geary, U	1
Yamasaki, H	1
Matsubara, S	1
Sasaki, I	1
Nagahiro, S	1
Shinohara, Y	3
Nishimaru, K	3
Schwab, S	2
Lee, SY	1
Savides, TJ	1
Katsuno, M	1
Teramoto, A	1
Taomoto, K	1
Ohnishi, H	1
Kuga, Y	1
Nakashima, K	1
Ichioka, T	1
Kodama, Y	1
Kubota, H	1
Tominaga, T	1
Hirose, T	1
Hayashi, M	1
Kinugasa, C	1
Yamamoto, J	1
Nema, H	1
Kato, M	1
Maguire, M	1
Seidi, O	1
Baker, M	1
Gupta, A	1
Muwanga, C	1
Katayama, Y	1
Handa, S	2
Matsuoka, K	1
Ohashi, Y	1
Yamamoto, H	2
Genka, C	1
Kitagawa, Y	1
Kusuoka, H	1
Tsushima, M	1
Koretsune, Y	1
Sawada, T	2
Hamada, C	1
England, TJ	1
Sare, GM	1
Geeganage, C	1
Moulin, T	1
O'Neill, D	1
Woimant, F	1
Christensen, H	1
De Deyn, P	1
Leys, D	3
Ringelstein, EB	1
Kimura, Y	2
Khemasuwan, D	1
Chae, YK	1
Gupta, S	1
Carpio, A	1
Yun, JH	1
Neagu, S	1
Lucca, AB	1
Valsecchi, ME	1
Mora, JI	1
Kasahara, Y	1
Nakagomi, T	1
Matsuyama, T	1
Stern, D	1
Taguchi, A	1
Bhatt, LK	1
Addepalli, V	1
Roa, LF	1
Hernandez, B	1
Merlos, M	1
Marquez, JM	1
Artigas, C	1
Perez, A	1
Cantu-Brito, C	1
Barinagarrementeria, F	1
Lee, SW	1
Park, SW	1
Flynn, RW	1
MacDonald, TM	1
Murray, GD	1
MacWalter, RS	1
Doney, AS	1
Weber, R	2
Weimar, C	1
Wanke, I	1
Möller-Hartmann, C	1
Gizewski, ER	1
Blatchford, J	1
Hermansson, K	1
Demchuk, AM	1
Forsting, M	1
Saver, JL	1
Warach, S	1
Diehl, A	1
Borelli, P	1
Baldacci, F	1
Vergallo, A	1
Del Dotto, P	1
Lucetti, C	1
Nuti, A	1
Bonuccelli, U	1
Renard, D	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embol[NCT02239120]	Phase 3	5,390 participants (Actual)	Interventional	2014-11-27	Completed
Secondary Prevention of Small Subcortical Strokes (SPS3) Trial[NCT00059306]	Phase 3	3,020 participants (Actual)	Interventional	2003-02-28	Completed
Post-marketing Study of Cilostazol: Study to Confirm Efficacy in Preventing Recurrent Cerebral Infarction in Comparison With Aspirin[NCT00234065]	Phase 4	2,800 participants (Actual)	Interventional	2003-12-31	Completed
PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes: A Double-blind, Active and Placebo Controlled Study of Aggrenox vs. Clopidogrel, With and Without Micardis[NCT00153062]	Phase 4	20,332 participants (Actual)	Interventional	2003-08-31	Completed
Antiplatelet Therapy in Secondary Prevention for Patient With Silent Brain Infarction[NCT03318744]		3,400 participants (Anticipated)	Interventional	2018-01-31	Not yet recruiting
Comparison of Triflusal With Aspirin in the Secondary Prevention of Atherothrombotic Events[NCT02616497]	Phase 4	1,220 participants (Actual)	Interventional	2015-09-30	Completed
Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A Randomized, Double-Blind, Aspirin-Controlled Trial[NCT00129805]	Phase 3	1,510 participants (Actual)	Interventional	2001-01-31	Completed
Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study[NCT02629653]		10 participants (Actual)	Interventional	2013-12-31	Completed
Evaluation of Diagnostic and Predictive Capabilities of Novel Application of Carotid Carotid Stenosis Pressure Gradient Measurement in Patients Undergoing Percutaneous Carotid Angioplasty and Stenting (CAS).[NCT06123767]		200 participants (Anticipated)	Interventional	2024-01-01	Not yet recruiting
Risk Factors for Complications After Carotid Endarterectomy: A Multicenter International Observational Study[NCT03788980]		10 participants (Actual)	Observational	2018-04-13	Terminated (stopped due to Lack of funding and resources)
Radial Versus Femoral Access For Carotid Artery Stenting In Patients With Carotid-Artery Stenosis ：a Prospective, Randomized, Multicenter, Noninferiority Trial[NCT05416853]		2,688 participants (Anticipated)	Interventional	2022-07-04	Recruiting
An Investigation of the Antidepressant Efficacy of an Antiglutamatergic Agent With Neurotrophic Properties in Major Depression[NCT00026052]	Phase 2	31 participants	Interventional	2001-11-30	Completed
Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial[NCT00991029]	Phase 3	4,881 participants (Actual)	Interventional	2010-05-28	Terminated (stopped due to The trial was halted by the DSMB.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Adjudicated composite of non-fatal stroke, non-fatal myocardial infarction (MI), or cardiovascular death is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

Adjudicated Fatal Bleed

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	4.80
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	5.40

Adjudicated fatal bleeding was defined as a bleeding event which the Independent Event Adjudication Committee (IAC) determined as the primary cause of death or contributed directly to death. The annualised event rate represents the average number of events per patient during a 1-year period. Because there were 0 events in one treatment group, the hazard ratio is unable to be calculated. (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

Adjudicated Intracranial Hemorrhage

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	0.00
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	0.05

"Adjudicated intracranial haemorrhage comprised the subtypes of intracerebral bleeds, intraventricular bleeds, subdural bleeds, epidural bleeds, and subarachnoid bleeds. Microbleeds did not qualify as intracranial haemorrhage, except when they were symptomatic.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

Adjudicated Ischaemic Stroke

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	0.67
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	0.63

Adjudicated ischaemic stroke is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

Adjudicated Life-threatening Bleed

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	3.97
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	4.71

"Major bleeds were to be classified as life-threatening if they met one or more of the following criteria: fatal bleed, symptomatic intracranial bleed, reduction in haemoglobin of at least 5 grams/ deciliter (g/dL), transfusion of at least 4 units of packed red blood cells (equivalent to 9 units in Japan), associated with hypotension requiring the use of intravenous inotropic agents, or necessitated surgical intervention.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

Adjudicated Recurrent Stroke

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	0.76
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	0.91

Adjudicated recurrent stroke (ischemic, hemorrhagic, or unspecified) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, approximately 43 months.

All-cause Death

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	4.09
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	4.80

All-cause death is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

Any Bleed (Investigator-reported)

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	1.24
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	1.28

"This was the sum of all major and minor bleeds (Minor bleeds were clinical bleeds that did not fulfil the criteria for major bleeds), regardless of severity.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

Disabling Stroke

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	15.21
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	11.64

Disabling stroke (modified Rankin Scale greater than or equal to 4, as determined 3 months after recurrent stroke) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

First Major Bleed (Adjudicated)

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	0.55
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	0.93

"First major bleed is primary safety endpoint. Major bleeds were defined according to the International Society of Thrombosis and Haemostasis (ISTH) definition as follows:~Symptomatic bleeding in a critical area or organ, such as intracranial, intraspinal, intraocular, retroperitoneal, intra-articular or pericardial, or intramuscular with compartment syndrome and/or,~Bleeding (which should be overt) associated with a reduction in haemoglobin of at least 2 grams/ decilitre (g/dL) (1.24 millimoles Per Litre (mmol/L)), or leading to transfusion of ≥2 units of blood or packed cells (equivalent to ≥4.5 units in Japan); the haemoglobin drop should be considered to be due to and temporally related to the bleeding event and/or,~Fatal bleed. The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

Number of Deaths From Any Cause

Intervention	Annualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)	1.84
Acetylsalicylic Acid, Aspirin (ASA) 100 mg	1.33

Number of deaths from any cause. The evaluation committee, whose members were unaware of patients' treatment assignment, adjudicated all trial endpoints. (NCT00234065)
Timeframe: From start of treatment to end of follow-up period ( follow-up periods : 29 months [STANDARD DEVIATION 16, range 1-59 months])

Number of Patients With First Occurrence of a Composite Endpoint of Stroke, Haemorrhagic Events, or Cardiovascular Events

Intervention	participants (Number)
Cilostazol	13
Aspirin	13

The endpoint in this measure is a composite endpoint of the first recurrence of cerebral infarction, or occurrence of cerebral haemorrhage, subarachnoid haemorrhage, transient ischaemic attack, angina pectris, myocardial infarction, heart failure, or haemorrhage requiring hospital admission. The evaluation committee, whose members were unaware of patients' treatment assignment, adjudicated all trial endpoints. (NCT00234065)
Timeframe: From start of treatment to end of follow-up period ( follow-up periods : 29 months [STANDARD DEVIATION 16, range 1-59 months])

Number of Patients With First Occurrence of Haemorrhagic Event

Intervention	participants (Number)
Cilostazol	138
Aspirin	186

The endpoint in this measure is a composite endpoint of the first occurrence of cerebral haemorrhage, subarachnoid haemorrhage or haemorrhage requiring hospital admission. The evaluation committee, whose members were unaware of patients' treatment assignment, adjudicated all trial endpoints. (NCT00234065)
Timeframe: From start of treatment to end of follow-up period ( follow-up periods : 29 months [STANDARD DEVIATION 16, range 1-59 months])

Number of Patients With First Occurrence of Ischaemic Cerebrovascular Disease

Intervention	participants (Number)
Cilostazol	23
Aspirin	57

The endpoint in this measure is a composite endpoint of the first recurrence of cerebral infarction or the first occurrence of transient ischaemic attack. The evaluation committee, whose members were unaware of patients' treatment assignment, adjudicated all trial endpoints. (NCT00234065)
Timeframe: From start of treatment to end of follow-up period ( follow-up periods : 29 months [STANDARD DEVIATION 16, range 1-59 months])

Number of Patients With First Recurrence of Cerebral Infarction

Intervention	participants (Number)
Cilostazol	86
Aspirin	103

(NCT00234065)
Timeframe: From start of treatment to end of follow-up period (mean follow-up periods : 29 months [STANDARD DEVIATION 16, range 1-59 months])

Numbers of Patients With First Occurence of Stroke

Intervention	participants (Number)
Cilostazol	72
Aspirin	88

The endpoint in this measure is a composite endpoint of the first recurrence of cerebral infarction, or occurrence of cerebral haemorrhage or subarachnoid haemorrhage. The evaluation committee, whose members were unaware of patients' treatment assignment, adjudicated all trial endpoints. (NCT00234065)
Timeframe: From start of treatment to end of follow-up period ( follow-up periods : 29 months [Standard Deviation 16, range 1-59 months])

Composite Outcome of Stroke, Myocardial Infarction (MI), or Vascular Death (Antiplatelet Comparison Only)

Intervention	participants (Number)
Cilostazol	82
Aspirin	119

Number of patients with any of stroke, myocardial infarction, vascular death (NCT00153062)
Timeframe: time since randomization; follow-up period is 1.5 to 4.4 years

Composite Outcome of Stroke, Myocardial Infarction, Vascular Death, or New or Worsening Congestive Heart Failure (CHF) (Telmisartan vs. Placebo Only)

Intervention	Participants (Number)
Aspirin + Extended Release Dipyridamole	1333
Clopidogrel	1333

Number of patients with any of stroke, myocardial infarction, vascular death, or new or worsening congestive heart failure (NCT00153062)
Timeframe: time since randomization; follow-up period is 1.5 to 4.4 years

Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Antiplatelet Comparison Only)

Intervention	Participants (Number)
Telmisartan	1367
Placebo	1463

(NCT00153062)
Timeframe: time since randomization; follow-up period is 1.5 to 4.4 years

Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Telmisartan vs. Placebo Only)

Intervention	Participants (Number)
Aspirin + Extended Release Dipyridamole	916
Clopidogrel	898

(NCT00153062)
Timeframe: time since randomization; follow-up period is 1.5 to 4.4 years

Number of Patients With New Onset of Diabetes (Telmisartan vs. Placebo Only)

Composite of Ischemic Stroke, Myocardial Infarction, Death From Ischemic Vascular Causes, or Major Hemorrhage

Intervention	Participants (Number)
Telmisartan	880
Placebo	934

Intervention	Participants (Number)
Telmisartan	125
Placebo	151

Secondary efficacy outcome: Number of participants with ischemic stroke, myocardial infarction, death from ischemic vascular causes, or major hemorrhage (NCT00991029)
Timeframe: Up to 90 days

Composite of Ischemic Stroke, Myocardial Infarction, or Death From Ischemic Vascular Causes

Intervention	Participants (Count of Participants)
Clopidogrel	141
Placebo	167

Primary efficacy outcome: Number of Participants with Ischemic Stroke, Myocardial Infarction, or Death From Ischemic Vascular Causes (NCT00991029)
Timeframe: Up to 90 days

Death From Any Cause

Intervention	Participants (Count of Participants)
Clopidogrel	121
Placebo	160

Other safety outcome: Number of Participants with Death from any cause (NCT00991029)
Timeframe: up to 90 days

Death From Ischemic Vascular Causes

Intervention	Participants (Count of Participants)
Clopidogrel	18
Placebo	12

Secondary efficacy outcome: Number of participants with Death from ischemic vascular causes (NCT00991029)
Timeframe: Up to 90 days

Hemorrhagic Stroke

Intervention	Participants (Count of Participants)
Clopidogrel	6
Placebo	4

Other safety outcome: Number of participants with Hemorrhagic stroke (NCT00991029)
Timeframe: up to 90 days

Ischemic or Hemorrhagic Stroke

Intervention	Participants (Count of Participants)
Clopidogrel	5
Placebo	3

Secondary efficacy outcome: Number of participants with Ischemic or hemorrhagic stroke (NCT00991029)
Timeframe: Up to 90 days

Ischemic Stroke

Intervention	Participants (Count of Participants)
Clopidogrel	116
Placebo	156

Secondary efficacy outcome:Number of participants with Ischemic stroke (NCT00991029)
Timeframe: Up to 90 days

Major Hemorrhage

Intervention	Participants (Count of Participants)
Clopidogrel	112
Placebo	155

Primary safety outcome: Number of Participants with major hemorrhage (NCT00991029)
Timeframe: Up to 90 days

Major Hemorrhage Other Than Intracranial Hemorrhage

Intervention	Participants (Count of Participants)
Clopidogrel	23
Placebo	10

Other safety outcome: Number of Participants with Major hemorrhage other than intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days

Minor Hemorrhage

Intervention	Participants (Count of Participants)
Clopidogrel	17
Placebo	7

Other safety outcome:Number of Participants with Minor hemorrhage (NCT00991029)
Timeframe: up to 90 days

Myocardial Infarction

Intervention	Participants (Count of Participants)
Clopidogrel	40
Placebo	13

Secondary efficacy outcome: Number of participants with Myocardial infarction (NCT00991029)
Timeframe: Up to 90 days

Other Symptomatic Intracranial Hemorrhage

Intervention	Participants (Count of Participants)
Clopidogrel	10
Placebo	7

Other safety outcome: Number of participants with other symptomatic intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days

Symptomatic Intracerebral Hemorrhage

Intervention	Participants (Count of Participants)
Clopidogrel	2
Placebo	0

Other safety outcome: Number of participants with Symptomatic intracerebral hemorrhage (NCT00991029)
Timeframe: up to 90 days

Reviews

Trials

Other Studies

193 other studies available for aspirin and Anterior Choroidal Artery Infarction

Article	Year
Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis. Medicine, 2021, Dec-17, Volume: 100, Issue:50 Topics: Aspirin; Brain Ischemia; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Hu	2021
Thyroid storm complicated by corpus callosum infarction in a young patient: A case report and literature review. Medicine, 2022, Aug-26, Volume: 101, Issue:34 Topics: Adult; Aspirin; Cerebral Infarction; Corpus Callosum; Humans; Magnetic Resonance Imaging; Male; Stro	2022
Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences, 2022, 11-15, Volume: 442 Topics: Adult; Anemia, Sickle Cell; Anticoagulants; Aspirin; Cerebral Infarction; Humans; Hydroxyurea; Strok	2022
Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A Systematic Evaluation and Meta-analysis. Current pharmaceutical design, 2023, Volume: 29, Issue:25 Topics: Acute Disease; Aspirin; Brain Ischemia; Cerebral Infarction; Drugs, Chinese Herbal; Humans; Stroke;	2023
Clinical Updates on Antiplatelet Therapy for Secondary Prevention in Acute Ischemic Stroke. Acta neurologica Taiwanica, 2023, Sep-30, Volume: 32(3) Topics: Aspirin; Cerebral Infarction; Clopidogrel; Humans; Ischemic Attack, Transient; Ischemic Stroke; Plat	2023
P2Y12 receptor inhibitor plus aspirin versus aspirin treated within 24 hours of acute noncardioembolic ischemic stroke or TIA: Meta-analysis. Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:6 Topics: Aspirin; Cerebral Infarction; Drug Therapy, Combination; Hemorrhage; Humans; Intracranial Hemorrhage	2022
Aspirin plus dipyridamole has the highest surface under the cumulative ranking curves (SUCRA) values in terms of mortality, intracranial hemorrhage, and adverse event rate among 7 drug therapies in the treatment of cerebral infarction. Medicine, 2018, Volume: 97, Issue:13 Topics: Aspirin; Cerebral Infarction; Cilostazol; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Hema	2018
Comparative efficacy of Chinese herbal injections for treating acute cerebral infarction: a network meta-analysis of randomized controlled trials. BMC complementary and alternative medicine, 2018, Apr-03, Volume: 18, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Bayes Theorem; Cerebral Infarction; Drugs,	2018
Effects of six types of aspirin combination medications for treatment of acute cerebral infarction in China: A network meta-analysis. Journal of clinical pharmacy and therapeutics, 2019, Volume: 44, Issue:1 Topics: Acute Disease; Aspirin; Cerebral Infarction; China; Drug Therapy, Combination; Humans; Network Meta-	2019
[Antiplatelet therapy for secondary prevention of cerebral infarction]. Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:7 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Humans; Japan; Platelet Aggreg	2014
The efficacy and safety of cilostazol for the secondary prevention of ischemic stroke in acute and chronic phases in Asian population--an updated meta-analysis. BMC neurology, 2014, Dec-20, Volume: 14 Topics: Acute Disease; Asian People; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Chronic Disease; Cil	2014
Dual antiplatelet therapy for secondary stroke prevention: Use of clopidogrel and acetylsalicylic acid after noncardioembolic ischemic stroke. Canadian family physician Medecin de famille canadien, 2016, Volume: 62, Issue:8 Topics: Aged, 80 and over; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Female; Hum	2016
Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008. Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:3 Topics: Aspirin; Awards and Prizes; Biomedical Research; CADASIL; Cardiovascular Agents; Cardiovascular Dise	2008
[Management of NSAIDs and low-dose-aspirin-induced ulcer in patients with cerebral infarction]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Humans; Peptic Ulcer	2011
How baseline severity affects efficacy and safety outcomes in acute ischemic stroke intervention trials. Annals of the New York Academy of Sciences, 2012, Volume: 1268 Topics: Acute Disease; Anticoagulants; Aspirin; Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage;	2012
[Susac syndrome as a cause of sensorineural hearing loss]. Acta otorrinolaringologica espanola, 2002, Volume: 53, Issue:5 Topics: Adult; Anti-Inflammatory Agents; Aspirin; Cerebral Infarction; Cochlea; Combined Modality Therapy; D	2002
Stroke management. Clinical evidence, 2002, Issue:7 Topics: Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Combined Modality Therapy; Humans; Neuroprotectiv	2002
Anticoagulants versus antiplatelet agents for acute ischaemic stroke. The Cochrane database of systematic reviews, 2002, Issue:4 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Heparin; Humans; Platelet Aggregation Inhibitors; Rand	2002
Stroke management. Clinical evidence, 2002, Issue:8 Topics: Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Combined Modality Therapy; Humans; Neuroprotectiv	2002
[Treatment of acute stroke -- an overview]. Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9 Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Brain Edema; Case-Control Studies; Cereb	2003
[Atrial fibrillation and stroke]. Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9 Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrilla	2003
[Lacunar infarcts]. Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:9 Topics: Adult; Aged; Aspirin; Autopsy; Brain; Carotid Stenosis; Cerebral Infarction; Dementia; Female; Fibri	2003
[EBM of cerebral infarction: message from mega-studies]. Rinsho shinkeigaku = Clinical neurology, 2003, Volume: 43, Issue:11 Topics: Anticoagulants; Aspirin; Azetidines; Benzylamines; Cerebral Infarction; Clopidogrel; Dipyridamole; D	2003
Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection. Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:2 Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Aspirin; Blood Vessels; Cardiotonic Agents; C	2005
[Patient with antithrombotic medication. Which do bleedings or preoperative?]. Laryngo- rhino- otologie, 2006, Volume: 85, Issue:1 Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atherosc	2006
[Adding aspirin to clopidogrel in secondary prevention of ischemic stroke: no significant benefits. Results of the Match study]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:4 Pt 2 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Follow-Up Studies; Hemorrhage;	2006
Current developments in anti-platelet therapy. Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:17-18 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Clopidogrel; Drug Resistance;	2006
[Current aspects of secondary prevention of ischemic stroke]. Der Nervenarzt, 2007, Volume: 78, Issue:10 Topics: Aspirin; Cerebral Infarction; Cholesterol, LDL; Clopidogrel; Delayed-Action Preparations; Dipyridamo	2007
Cardiogenic cerebral embolism. Comprehensive therapy, 1984, Volume: 10, Issue:9 Topics: Anticoagulants; Aspirin; Cardiac Surgical Procedures; Cerebral Hemorrhage; Cerebral Infarction; Dipy	1984
[Specific measures in drug therapy in stroke. Anticoagulants, inhibitors of thrombocyte aggregation, initial barbiturate therapy]. Der Nervenarzt, 1980, Volume: 51, Issue:8 Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Barbiturates; Carotid Arteries; Cerebral Infar	1980
[Antithrombotic treatment in chronic nonrheumatic atrial fibrillation]. Duodecim; laaketieteellinen aikakauskirja, 1993, Volume: 109, Issue:19 Topics: Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Cerebral Infarction; Chronic Disease; Clinica	1993
[Prevention of cerebrovascular insults]. Schweizerische medizinische Wochenschrift, 1994, Nov-12, Volume: 124, Issue:45 Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Carotid Stenosis; Cerebral Infarction; Diet; Fem	1994
[Carotid endarterectomy--results of current studies and their consequences]. Medizinische Klinik (Munich, Germany : 1983), 1993, Oct-15, Volume: 88, Issue:10 Topics: Aspirin; Carotid Stenosis; Cerebral Infarction; Clinical Trials as Topic; Endarterectomy, Carotid; H	1993
[Platelet aggregation inhibitor and brain infarct: quo vadis?]. Schweizerische medizinische Wochenschrift, 1993, Apr-10, Volume: 123, Issue:14 Topics: Aspirin; Cerebral Infarction; Dose-Response Relationship, Drug; Humans; Myocardial Infarction; Plate	1993
Incidence, natural history, and risk factors in lacunar infarction. Advances in neurology, 1993, Volume: 62 Topics: Age Factors; Aged; Aspirin; Cardiovascular Diseases; Cerebral Infarction; Diabetic Angiopathies; Fem	1993
[High dosage acetylsalicylic acid administration for prevention of acute cerebral ischemia]. Der Nervenarzt, 1995, Volume: 66, Issue:12 Topics: Aspirin; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Ischemi	1995
[Aspirin dosage for prevention of cerebral infarct: arguments for low dosage]. Der Nervenarzt, 1995, Volume: 66, Issue:12 Topics: Aspirin; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administra	1995
[Advances in therapy and prevention of ischemic myocardial infarct]. Schweizerische medizinische Wochenschrift, 1997, Oct-04, Volume: 127, Issue:40 Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Drug Interactions; Fibrinolytic Agents; Hepa	1997
[Acute cerebral infarct: physiopathology and modern therapeutic concepts]. Der Radiologe, 1997, Volume: 37, Issue:11 Topics: Acute Disease; Anticoagulants; Aspirin; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circula	1997
[The risk of hemorrhage in long-term use of aspirin and triflusal]. Revista de neurologia, 1998, Volume: 27, Issue:160 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Female; Follow-Up Stud	1998
[Current status and future prospects in the treatment of acute-phase cerebral infarction]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9 Topics: Acute-Phase Reaction; Aspirin; Brain Edema; Calcium Channel Blockers; Cerebral Infarction; Fibrinoly	1999
[Aspirin and cerebral ischemic accidents]. La Revue de medecine interne, 2000, Volume: 21 Suppl 1 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Cerebral Infarction; Clinica	2000
[Transient ischemic attacks and prolonged reversible ischemic neurologic deficit. Diagnosis, differential diagnosis and treatment]. Praxis, 2000, Mar-23, Volume: 89, Issue:13 Topics: Aspirin; Brain Ischemia; Cerebral Infarction; Diagnosis, Differential; Dipyridamole; Endarterectomy,	2000
[Antithrombotic therapy in cerebral infarction]. Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:12 Topics: Acute-Phase Reaction; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Heparin; Hu	2000
[Heparin or aspirin in the treatment of acute cerebral infarction?]. La Revue du praticien, 2001, Dec-01, Volume: 51, Issue:19 Topics: Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Fibrinolytic Agents; Heparin; Humans; Patient Sel	2001
[Prevention of recurrence in cerebral infarction]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2002, Mar-20, Volume: 91 Suppl Topics: Anticoagulants; Arteriosclerosis; Aspirin; Atrial Fibrillation; Cerebral Infarction; Drug Therapy, C	2002
[Epidemiological study of cerebral infarction and transient cerebral ischemic attack in Japan]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl Topics: Adult; Aged; Aspirin; Cerebral Infarction; Diagnosis, Differential; Female; Humans; Ischemic Attack,	1992
Review: atrial fibrillation and stroke prevention. Age and ageing, 1992, Volume: 21, Issue:5 Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Heart At	1992
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly. Clinics in geriatric medicine, 1991, Volume: 7, Issue:3 Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem	1991
Therapy in cerebrovascular disease: current status and future directions. The Medical journal of Australia, 1991, Oct-21, Volume: 155, Issue:8 Topics: Age Factors; Anticoagulants; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Forecasting; H	1991
Thromboembolic complications in atrial fibrillation. Stroke, 1990, Volume: 21, Issue:1 Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Chronic Disease; Female; Fo	1990
[Hypercoagulability and cerebral infarction]. No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:4 Topics: Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Cerebral Infarction; Clinica	1986
Diagnosis and initial management of stroke. Comprehensive therapy, 1988, Volume: 14, Issue:7 Topics: Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Endarterectomy; Humans; Risk Factors	1988
Lacunar infarcts. Clinical neurology and neurosurgery, 1986, Volume: 88, Issue:1 Topics: Aspirin; Ataxia; Cerebral Angiography; Cerebral Infarction; Corpus Striatum; Electroencephalography;	1986
[Thrombosis in various diseases: cerebral infarction]. Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:5 Topics: Aspirin; Blood Coagulation; Cerebral Infarction; Fibrinolysis; Humans; Intracranial Embolism and Thr	1986

Article	Year
Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA neurology, 2022, Mar-01, Volume: 79, Issue:3 Topics: Aged; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Female; Humans; Ischemic	2022
Predictors of Recurrent Stroke After Embolic Stroke of Undetermined Source in the RE-SPECT ESUS Trial. Journal of the American Heart Association, 2022, 06-07, Volume: 11, Issue:11 Topics: Aspirin; Cerebral Infarction; Dabigatran; Embolic Stroke; Humans; Intracranial Embolism; Male; Risk	2022
Dual antiplatelet therapy with cilostazol in stroke patients with extracranial arterial stenosis or without arterial stenosis: A subgroup analysis of the CSPS.com trial. International journal of stroke : official journal of the International Stroke Society, 2023, Volume: 18, Issue:4 Topics: Aspirin; Cerebral Infarction; Cilostazol; Clopidogrel; Constriction, Pathologic; Drug Therapy, Combi	2023
Aminotransferase Level and the Effects of Dual Antiplatelet in Minor Stroke or Transient Ischemic Attack: A post hoc Analysis of a Randomized Control Trial. Cerebrovascular diseases (Basel, Switzerland), 2023, Volume: 52, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fema	2023
Aminotransferase Level and the Effects of Dual Antiplatelet in Minor Stroke or Transient Ischemic Attack: A post hoc Analysis of a Randomized Control Trial. Cerebrovascular diseases (Basel, Switzerland), 2023, Volume: 52, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fema	2023
Aminotransferase Level and the Effects of Dual Antiplatelet in Minor Stroke or Transient Ischemic Attack: A post hoc Analysis of a Randomized Control Trial. Cerebrovascular diseases (Basel, Switzerland), 2023, Volume: 52, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fema	2023
Aminotransferase Level and the Effects of Dual Antiplatelet in Minor Stroke or Transient Ischemic Attack: A post hoc Analysis of a Randomized Control Trial. Cerebrovascular diseases (Basel, Switzerland), 2023, Volume: 52, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Fema	2023
Genotype-Guided Dual Antiplatelet Use for Transient Ischemic Attack and Minor Stroke by Imaging Status: Subgroup Analysis of the CHANCE-2 Trial. Annals of neurology, 2023, Volume: 93, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Genotype; Hemorrhage; Humans;	2023
Vulnerable and Stabilized States After Cerebral Ischemic Events: Implications of Kinetic Modeling in the SOCRATES, POINT, and THALES Trials. Neurology, 2023, Nov-27, Volume: 101, Issue:22 Topics: Aspirin; Cerebral Infarction; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Platele	2023
[Different treatment modes for cerebral microlesions: a comparison of clinical efficacy]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2013, Volume: 33, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain; Cerebral Infarction; Drugs, Chinese Herbal; Female;	2013
Morphological classification of penetrating artery pontine infarcts and association with risk factors and prognosis: The SPS3 trial. International journal of stroke : official journal of the International Stroke Society, 2016, Volume: 11, Issue:4 Topics: Antihypertensive Agents; Aspirin; Cerebral Infarction; Clopidogrel; Constriction, Pathologic; Double	2016
Efficacy and Safety of Vinpocetine as Part of Treatment for Acute Cerebral Infarction: A Randomized, Open-Label, Controlled, Multicenter CAVIN (Chinese Assessment for Vinpocetine in Neurology) Trial. Clinical drug investigation, 2016, Volume: 36, Issue:9 Topics: Aged; Anticoagulants; Aspirin; Cerebral Infarction; Cerebrovascular Circulation; China; Clopidogrel;	2016
[Effect of tongxinluo capsule on platelet aggregation in patients with cerebral infarction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2008, Volume: 28, Issue:4 Topics: Aged; Aged, 80 and over; Aspirin; Capsules; Cerebral Infarction; Drug Therapy, Combination; Drugs, C	2008
[Clinical value of protoparaxotril saporlirs combined with aspirin in the secondary prevention of cerebral infarction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2008, Volume: 28, Issue:9 Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ma	2008
[Effects of puerarin with aspirin on the markers of damaged vascular endothelial cells in patients with acute cerebral infarction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:23 Topics: Acute Disease; Aged; Aspirin; Cerebral Infarction; Endothelial Cells; Female; Humans; Isoflavones; M	2008
Sarpogrelate versus aspirin in secondary prevention of cerebral infarction: differential efficacy in diabetes? Subgroup analysis from S-ACCESS. Stroke, 2009, Volume: 40, Issue:8 Topics: Aged; Aspirin; Cerebral Infarction; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-U	2009
Platelet function and spontaneous thrombolytic activity of patients with cerebral infarction assessed by the global thrombosis test. Pathophysiology of haemostasis and thrombosis, 2010, Volume: 37, Issue:1 Topics: Adult; Aged; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Cerebral Infarction; Femal	2010
Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial. The Lancet. Neurology, 2010, Volume: 9, Issue:10 Topics: Adult; Aged; Aspirin; Cerebral Infarction; Cilostazol; Double-Blind Method; Female; Follow-Up Studie	2010
Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke Trial. Stroke, 2010, Volume: 41, Issue:12 Topics: Aged; Anticoagulants; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Dose-Response Relationship,	2010
Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy. Stroke, 2012, Volume: 43, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; C	2012
Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy. Stroke, 2012, Volume: 43, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; C	2012
Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy. Stroke, 2012, Volume: 43, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; C	2012
Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy. Stroke, 2012, Volume: 43, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Benzimidazoles; Benzoates; Brain Ischemia; C	2012
Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial. Stroke, 2003, Volume: 34, Issue:4 Topics: Aspirin; Cardiovascular Diseases; Cerebral Infarction; Double-Blind Method; Female; Hemorrhage; Huma	2003
Ticlopidine alone versus ticlopidine plus aspirin for preventing recurrent stroke. Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:9 Topics: Adult; Aged; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic Attac	2003
Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. Stroke, 2004, Volume: 35, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Black People; Cerebral Infarction; Dose-Response R	2004
Triflusal vs aspirin for prevention of cerebral infarction: a randomized stroke study. Neurology, 2004, Apr-13, Volume: 62, Issue:7 Topics: Aged; Aspirin; Cerebral Infarction; Double-Blind Method; Female; Follow-Up Studies; Humans; Ischemic	2004
Effect of the principle of activating blood circulation to break stasis on GMP-140 and D2 dimer in patients with acute cerebral infarction. Chinese journal of integrative medicine, 2005, Volume: 11, Issue:1 Topics: Acute Disease; Aged; Aspirin; Blood Circulation; Blood Platelets; Cerebral Infarction; Female; Fibri	2005
Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction. Chinese journal of integrative medicine, 2005, Volume: 11, Issue:2 Topics: Acute Disease; Adult; Aged; Aspirin; Blood Viscosity; Capsules; Cerebral Infarction; Cytidine Diphos	2005
[The changes and effects of antiplatelet agents on platelet-leukocyte aggregation in patients with acute cerebral infarction]. Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:7 Topics: Aged; Aspirin; C-Reactive Protein; Cerebral Infarction; Clopidogrel; Female; Humans; Male; Middle Ag	2007
Long-term occurrence of death and cardiovascular events in patients with transient ischaemic attack or minor ischaemic stroke: comparison between arterial and cardiac source of the index event. Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8 Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cause of Death; Cerebral Hemorrhage; Cerebral In	2008
The effects of antiplatelet agents on platelet-leukocyte aggregations in patients with acute cerebral infarction. Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:2 Topics: Aged; Aspirin; Blood Platelets; Cell Adhesion; Cerebral Infarction; Clopidogrel; Female; Humans; Leu	2009
Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A randomized, double-blind, aspirin-controlled trial. Stroke, 2008, Volume: 39, Issue:6 Topics: Aged; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Double-Blind Method; Female; Humans; Incide	2008
[The A.I.C.L.A. controlled cooperative trial. Secondary prevention of cerebral ischemic accidents due to atherosclerosis by aspirin and dipyridamole. 3: Results]. Revue neurologique, 1983, Volume: 139, Issue:5 Topics: Aspirin; Brain Ischemia; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Drug Therapy,	1983
Anticoagulant and platelet-antiaggregating therapy in stroke and threatened stroke. Neurologic clinics, 1983, Volume: 1, Issue:1 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Clinical Trials as Topic; C	1983
[The treatment of transitory ischemic attacks with acetylsalicylic acid: results of a double-blind-study (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1980, May-23, Volume: 122, Issue:21 Topics: Aspirin; Cerebral Infarction; Humans; Ischemic Attack, Transient; Placebos; Recurrence; Vertebrobasi	1980
[Controlled cooperative trial. Secondary prevention of atherosclerosis-related cerebral ischemic accidents by aspirin dipyridamole. 2: Description of subjects at the beginning of the trial]. Revue neurologique, 1982, Volume: 138, Issue:1 Topics: Aged; Aspirin; Brain Ischemia; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Drug The	1982
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA, 1995, May-10, Volume: 273, Issue:18 Topics: Adult; Aged; Angiography; Aspirin; Carotid Stenosis; Cerebral Infarction; Endarterectomy; Female; Fo	1995
The effect of aspirin on neurodeficit and platelet aggregability in acute ischemic cerebral strokes. The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:6 Topics: Adult; Aged; Aspirin; Carotid Stenosis; Cerebral Infarction; Dose-Response Relationship, Drug; Femal	1994
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease. Assessment by platelet aggregation testing. Stroke, 1994, Volume: 25, Issue:12 Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Collagen; Drug Monitoring; Female; Follow	1994
Silent infarction on a second CT scan in 91 patients without manifest stroke in the Dutch TIA trial. Clinical neurology and neurosurgery, 1994, Volume: 96, Issue:3 Topics: Adult; Aged; Aspirin; Atenolol; Cerebral Infarction; Female; Humans; Ischemic Attack, Transient; Mal	1994
The role of autopsy findings in multicenter treatment evaluations as exemplified by two aspirin trials. Quality assurance in health care : the official journal of the International Society for Quality Assurance in Health Care, 1993, Volume: 5, Issue:4 Topics: Aspirin; Autopsy; Cause of Death; Cerebral Infarction; Death, Sudden, Cardiac; Diagnostic Errors; Do	1993
Comparison of symptomatic and asymptomatic reinfarctions after small subcortical stroke. European neurology, 1994, Volume: 34, Issue:3 Topics: Aged; Aspirin; Cerebral Angiography; Cerebral Infarction; Cholesterol, HDL; Female; Fibrinogen; Foll	1994
Shear-induced platelet aggregation in cerebral ischemia. Stroke, 1994, Volume: 25, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Aspirin; beta-Thromboglobulin; Brain Ischemia; Cerebral Infarction;	1994
[SPIRIT: new life spirit for anticoagulant treatment in the secondary prevention of brain infarcts? A new study. Stroke Prevention in Reversible Ischaemia Trial]. Nederlands tijdschrift voor geneeskunde, 1994, May-14, Volume: 138, Issue:20 Topics: Aspirin; Cerebral Infarction; Coumarins; Humans; Ischemic Attack, Transient	1994
Antiplatelet therapy is effective in primary prevention of myocardial infarction in patients with a previous cerebrovascular ischemic event. Archives of neurology, 1993, Volume: 50, Issue:7 Topics: Aged; Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemi	1993
European Stroke Prevention Study (ESPS): antithrombotic therapy is also effective in the elderly. Acta neurologica Scandinavica, 1993, Volume: 87, Issue:2 Topics: Actuarial Analysis; Aged; Aspirin; Cause of Death; Cerebral Infarction; Cerebrovascular Disorders; D	1993
Interobserver agreement in the classification of stroke in the physicians' health study. Stroke, 1996, Volume: 27, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aspirin; beta Carotene; Carotenoids; Cerebral Hemorrhage; Cerebral I	1996
Aspirin improves the enhanced erythrocyte aggregability in patients with cerebral infarction. Journal of the neurological sciences, 1996, Volume: 139, Issue:1 Topics: Adult; Aged; Aspirin; Cerebral Infarction; Erythrocyte Aggregation; Female; Fibrinogen; Hematocrit;	1996
An analysis of perioperative surgical mortality and morbidity in the asymptomatic carotid atherosclerosis study. ACAS Investigators. Asymptomatic Carotid Atherosclerosis Study. Stroke, 1996, Volume: 27, Issue:12 Topics: Anesthesia; Arteriosclerosis; Aspirin; Carotid Stenosis; Cerebral Infarction; Combined Modality Ther	1996
Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. Circulation, 1999, May-11, Volume: 99, Issue:18 Topics: Acute Disease; Age Factors; Aged; Angina, Unstable; Aspirin; Brain Damage, Chronic; Cerebral Hemorrh	1999
[Secondary prevention after ischemic cerebral infarct. The ESPRIT Study: low dose anticoagulation, combined therapy with acetylsalicylic acid/dipyridamole or monotherapy with acetylsalicylic acid?]. Der Nervenarzt, 1999, Volume: 70, Issue:4 Topics: Anticoagulants; Aspirin; Australia; Cerebral Infarction; Dipyridamole; Dose-Response Relationship, D	1999
Heparin thromboprophylaxis after acute stroke. Age and ageing, 2001, Volume: 30, Issue:1 Topics: Acute Disease; Aged; Aspirin; Cause of Death; Cerebral Hemorrhage; Cerebral Infarction; Contraindica	2001
[Does early high dosage dipyridamole in prevention of secondary stroke induce cardiac events?]. Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:5 Topics: Administration, Oral; Angina Pectoris; Aspirin; Cause of Death; Cerebral Infarction; Delayed-Action	2001
Measurement of platelet fibrinogen binding and p-selectin expression by flow cytometry in patients with cerebral infarction. Thrombosis research, 2001, Nov-01, Volume: 104, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cerebral Infarction; Drug Therapy, Combina	2001
Differences in the outcome of patients with TIA versus minor stroke. Acta neurologica Scandinavica, 1992, Volume: 85, Issue:3 Topics: Adolescent; Adult; Aged; Anticoagulants; Aspirin; Cause of Death; Cerebral Infarction; Dose-Response	1992
Epidemiology of and stroke-preventive strategies for atherothromboembolic brain infarction in the elderly. Clinics in geriatric medicine, 1991, Volume: 7, Issue:3 Topics: Aged; Anticoagulants; Arteriosclerosis; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Fem	1991
A randomized trial of aspirin or heparin in hospitalized patients with recent transient ischemic attacks. A pilot study. Stroke, 1989, Volume: 20, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Infarction; Clinical Trials as Topic;	1989
[Hypercoagulability and cerebral infarction]. No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:4 Topics: Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Cerebral Infarction; Clinica	1986

Article	Year
Relation of Pre-Stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes. Annals of neurology, 2021, Volume: 90, Issue:5 Topics: Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Brain Ischemia; Cerebral Infarction; Female; Fibr	2021
Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke. Mayo Clinic proceedings, 2022, Volume: 97, Issue:8 Topics: Aged; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrh	2022
Multiple cerebral infarctions due to calcified amorphous tumor growing rapidly from an antecedent infection and decreasing rapidly by detachment of fibrin and antithrombotic drugs: a case report. BMC neurology, 2022, Oct-22, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Aspirin; Calcinosis; Calcium; Cerebral Infarction; Female; Fibrin; Fibrinolyt	2022
Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China. Genetics research, 2022, Volume: 2022 Topics: Aged; Aspirin; Cerebral Infarction; China; Clopidogrel; Coronary Disease; Cytochrome P-450 CYP2C19;	2022
Ticagrelor Aspirin vs Clopidogrel Aspirin in Neurology, 2023, 01-31, Volume: 100, Issue:5 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Huma	2023
Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy. Clinical neurology and neurosurgery, 2023, Volume: 231 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; H	2023
Pharmacological Effects of a New Soluble Guanylate Cyclase Stimulator in Experimental Ischemic Stroke. Bulletin of experimental biology and medicine, 2023, Volume: 175, Issue:6 Topics: Animals; Aspirin; Brain Ischemia; Cerebral Infarction; Ischemic Stroke; Platelet Aggregation; Platel	2023
Bilateral paramedian pontine infarcts: a rare cause of bilateral horizontal gaze palsy. BMJ case reports, 2019, Oct-31, Volume: 12, Issue:10 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atrial Flutter; Brain; Cerebral Infarction;	2019
CSPS.com Trial of Adding Cilostazol to Antiplatelet Therapy to Reduce Recurrent Stroke. Stroke, 2020, Volume: 51, Issue:2 Topics: Aspirin; Cerebral Infarction; Cilostazol; Drug Therapy, Combination; Female; Humans; Male; Middle Ag	2020
Association of aspirin resistance with 4-hydroxynonenal and its impact on recurrent cerebral infarction in patients with acute cerebral infarction. Brain and behavior, 2020, Volume: 10, Issue:3 Topics: Aged; Aldehydes; Aspirin; Cerebral Infarction; Drug Resistance; Female; Humans; Male; Middle Aged; P	2020
Cerebral Infarction in an Elderly Patient with Coronavirus Disease. Revista da Sociedade Brasileira de Medicina Tropical, 2020, Volume: 53 Topics: Aged, 80 and over; Anticoagulants; Aspirin; Betacoronavirus; Cerebral Infarction; Coronavirus; Coron	2020
[Study on clinical characteristics of Danshen Chuanxiongqin Injection in treatment of cerebral infarction in real world]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020, Volume: 45, Issue:14 Topics: Aged; Aspirin; Cerebral Infarction; China; Drugs, Chinese Herbal; Humans; Male; Medicine, Chinese Tr	2020
Effect of platelet count on long-term prognosis of cerebral infarction. Restorative neurology and neuroscience, 2020, Volume: 38, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain; Cerebral Infarction; Female; Humans; Male; Middle Ag	2020
Unusual manifestation of heat stroke: Isolated trochlear nerve palsy. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:10 Topics: Aged; Aspirin; Cerebral Infarction; Fibrinolytic Agents; Heat Stroke; Humans; Male; Mesencephalon; R	2020
Acute bilateral cerebral infarction in the presence of neuromyelitis optica spectrum disorder: A case report. Medicine, 2020, Oct-02, Volume: 99, Issue:40 Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Anticholesteremic Agents; Aphasia,	2020
Short-Term Cessation of Dabigatran Causes a Paradoxical Prothrombotic State. Annals of neurology, 2021, Volume: 89, Issue:3 Topics: Aged; Aged, 80 and over; Animals; Antithrombins; Arachidonic Acid; Aspirin; Carotid Artery Thrombosi	2021
Effects of atorvastatin and aspirin on post-stroke epilepsy and usage of levetiracetam. Medicine, 2020, Dec-11, Volume: 99, Issue:50 Topics: Aged; Aged, 80 and over; Anticonvulsants; Aspirin; Atorvastatin; Cerebral Infarction; Drug Therapy,	2020
Image and clinical analysis of common carotid web: a case report. BMC medical imaging, 2021, 01-06, Volume: 21, Issue:1 Topics: Aged; Anticoagulants; Aspirin; Basal Ganglia Diseases; Carotid Artery Diseases; Carotid Artery, Comm	2021
57-Year-Old Woman With Weakness and Word-Finding Difficulties. Mayo Clinic proceedings, 2021, Volume: 96, Issue:2 Topics: Adenocarcinoma, Clear Cell; Antibodies, Antiphospholipid; Aspirin; Biomarkers, Tumor; Cerebral Infar	2021
Ataxia and Headache in a Child: A Case of Acute Cerebellar Infarction. Pediatric emergency care, 2017, Volume: 33, Issue:8 Topics: Acute Disease; Anticoagulants; Aspirin; Cerebellar Ataxia; Cerebellum; Cerebral Infarction; Child, P	2017
Beneficial Effect of Beraprost Sodium Plus Aspirin in the Treatment of Acute Ischemic Stroke. Medical science monitor : international medical journal of experimental and clinical research, 2017, Sep-12, Volume: 23 Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Infarction; Drug Therapy, Combination; Ep	2017
Unilateral Thalamic Infarct Presenting as a Convulsive Seizure. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2017, Volume: 27, Issue:9 Topics: Aspirin; Atorvastatin; Cerebral Angiography; Cerebral Infarction; Humans; Hydrocephalus; Levetiracet	2017
Aspirin ameliorates cerebral infarction through regulation of TLR4/NF‑κB‑mediated endoplasmic reticulum stress in mouse model. Molecular medicine reports, 2018, Volume: 17, Issue:1 Topics: Animals; Apoptosis; Aspirin; Biomarkers; Cerebral Infarction; Disease Models, Animal; Endoplasmic Re	2018
Evaluation of efficacy and safety of Reteplase and Alteplase in the treatment of hyper-acute cerebral infarction. Bioscience reports, 2018, 02-28, Volume: 38, Issue:1 Topics: Aged; Aspirin; Cerebral Infarction; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Combinatio	2018
Continuous Acetylsalicylic Acid Treatment Does Not Influence Bleeding Pattern or Outcome of Aneurysmal Subarachnoid Hemorrhage: A Matched-Pair Analysis. World neurosurgery, 2018, Volume: 113 Topics: Aged; Aneurysm, Ruptured; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Female; Follow-Up Studi	2018
Cilostazol May Decrease Plasma Inflammatory Biomarkers in Patients with Recent Small Subcortical Infarcts: A Pilot Study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:6 Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Cerebral Infarction; Chi-Square Distribution; Cilostaz	2018
Cortical laminar necrosis in a case of migrainous cerebral infarction. BMJ case reports, 2018, Mar-28, Volume: 2018 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Cerebral Cortex; Cerebral	2018
Anteromedial thalamic infarct: a rare presentation. BMJ case reports, 2018, May-02, Volume: 2018 Topics: Aspirin; Blepharoptosis; Cerebral Infarction; Confusion; Diplopia; Female; Humans; Hydroxymethylglut	2018
Pain medication at ictus of subarachnoid hemorrhage-the influence of one-time acetylsalicylic acid usage on bleeding pattern, treatment course, and outcome: a matched pair analysis. Neurosurgical review, 2019, Volume: 42, Issue:2 Topics: Adult; Aged; Anticoagulants; Aspirin; Cerebral Infarction; Female; Fibrinolytic Agents; Headache; Ho	2019
Carotid Dissection and Cerebral Infarction From Posterior Oropharyngeal Trauma: The Diagnostic and Therapeutic Challenges. Pediatric emergency care, 2019, Volume: 35, Issue:1 Topics: Aspirin; Carotid Arteries; Carotid Artery, Internal, Dissection; Cerebral Infarction; Child, Prescho	2019
A Unique Recurrent Stroke Case due to Bilateral Vertebral Artery Dissection with Familial Hirschsprung Disease. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:8 Topics: Adult; Aspirin; Cerebral Angiography; Cerebral Infarction; Cilostazol; Diffusion Magnetic Resonance	2019
57-Year-Old Man With Vertigo. Mayo Clinic proceedings, 2019, Volume: 94, Issue:6 Topics: Aspirin; Cerebellum; Cerebral Infarction; Headache; Humans; Magnetic Resonance Angiography; Male; Mi	2019
Cerebral infarction in a case of Parry-Romberg syndrome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:2 Topics: Adult; Aspirin; Atorvastatin; Cerebral Infarction; Diffusion Magnetic Resonance Imaging; Facial Hemi	2014
Sarpogrelate- another new antiplatelet agent? JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:11 Topics: Aspirin; Cerebral Infarction; China; Female; Humans; Japan; Male; Platelet Aggregation Inhibitors; R	2012
Sudden bilateral vision loss and brain infarction following cosmetic hyaluronic acid injection. JAMA ophthalmology, 2013, Volume: 131, Issue:9 Topics: Acetazolamide; Antihypertensive Agents; Aspirin; Blindness; Cerebral Infarction; Cosmetic Techniques	2013
Enteric-coated aspirin versus other antiplatelet drugs in acute non-cardioembolic ischemic stroke: post-marketing study in Japan. Advances in therapy, 2014, Volume: 31, Issue:1 Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Dipyridamole	2014
[Clinical outcomes of parenterally administered shuxuetong--analysis of hospital information system data]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:18 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Infarction; Child; Drug Therapy, Combi	2013
[Case of cardiac tamponade during the treatment of acute cerebral infarction]. Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:3 Topics: Acute Disease; Adenocarcinoma; Anterior Cerebral Artery; Antipyrine; Aspirin; Cardiac Tamponade; Cer	2014
Association between silent embolic cerebral infarction and continuous increase of P2Y12 reaction units after neurovascular stenting. Journal of neurosurgery, 2014, Volume: 121, Issue:4 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Resistance; Endovascular Procedures; Female; Humans;	2014
[Analysis of clinical use of shuxuening injection in treatment of cerebral infarction based on real world]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:18 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atorvastatin; Cerebral Infarcti	2014
Claude's Syndrome without Ptosis Caused by a Midbrain Infarction. Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:14 Topics: Aged, 80 and over; Aspirin; Brain Stem Infarctions; Cerebral Infarction; Eye Movements; Humans; Magn	2015
Infectious Mononucleosis Complicated with Acute Cerebral Infarction: A Case Report. Acta neurologica Taiwanica, 2015, Volume: 24, Issue:1 Topics: Acute Disease; Aspirin; Cerebral Infarction; Fever; Fibrinolytic Agents; Humans; Infectious Mononucl	2015
[Recurrence of Cerebral Infarction Associated Aspirin Resistance or Chinese Medical Constitutions: a Correlation Study]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:10 Topics: Aspirin; Body Constitution; Cerebral Infarction; Drug Resistance; Humans; Medicine, Chinese Traditio	2015
Association between Postprocedural Infarction and Antiplatelet Drug Resistance after Coiling for Unruptured Intracranial Aneurysms. AJNR. American journal of neuroradiology, 2016, Volume: 37, Issue:6 Topics: Aged; Aspirin; Cerebral Infarction; Drug Resistance; Female; Humans; Intracranial Aneurysm; Magnetic	2016
High incidence of silent cerebral infarcts in adult patients with beta thalassemia major. Thrombosis research, 2016, Volume: 144 Topics: Adult; Aspirin; beta-Thalassemia; Cerebral Infarction; Cerebrum; Female; Ferritins; Fibrinolytic Age	2016
[ASS plus dipyridamole or clopidogrel after stroke: what is the best secondary prevention?]. MMW Fortschritte der Medizin, 2008, May-22, Volume: 150, Issue:21 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Germany; Humans;	2008
Hemorrhage from a falx meningioma after internal use of low-dose aspirin. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2008, Volume: 17, Issue:5 Topics: Aged; Aspirin; Cerebral Infarction; Female; Fibrinolytic Agents; Humans; Intracranial Hemorrhages; M	2008
Aspirin attenuates cerebral ischemic injury in diabetic rats. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2009, Volume: 117, Issue:4 Topics: Animals; Aspirin; Blood Glucose; Brain Ischemia; Cerebral Infarction; Diabetes Mellitus, Experimenta	2009
[Incremental cost-effectiveness of dipyridamole + acetylsalicylic acid in secondary prevention of ischemic noncardioembolic stroke]. Medizinische Klinik (Munich, Germany : 1983), 2008, Nov-15, Volume: 103, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cause of Death; Cerebral Infarction; Cost Savings; Cost-Ben	2008
[Recurrent idiopathic cerebral infarction in a 5-year-old boy, with emphasis on the importance of platelet aggregation analysis for appropriate selection of anti-platelet drugs]. No to hattatsu = Brain and development, 2009, Volume: 41, Issue:1 Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Tests; Cerebral Infarction; Child, Preschool; Cilo	2009
Variable number of tandem repeats polymorphism of platelet glycoprotein Ib alpha in Chinese people and CC genotype with aspirin sensitivity in patients with cerebral infarction. Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2 Topics: Aged; Alleles; Aspirin; Cerebral Infarction; China; Drug Resistance; Female; Genotype; Humans; Male;	2009
Caveats in the management and diagnosis of cerebellar infarct and vertebral artery dissection. Emergency medicine journal : EMJ, 2009, Volume: 26, Issue:4 Topics: Aspirin; Cerebellum; Cerebral Infarction; False Negative Reactions; Humans; Magnetic Resonance Imagi	2009
Retinal artery embolization during carotid angioplasty and carotid artery stenting: case report. Neurologia medico-chirurgica, 2009, Volume: 49, Issue:5 Topics: Aged; Angioplasty, Balloon; Anticoagulants; Antipyrine; Aspirin; Carotid Artery, External; Carotid S	2009
[Guidelines recommend aspirin/dipyridamole retard in high recurrence risk. Well protected from the second stroke]. MMW Fortschritte der Medizin, 2009, Jul-23, Volume: 151, Issue:30-33 Topics: Aged; Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topic	2009
Management of anticoagulation before and after gastrointestinal endoscopy. The American journal of gastroenterology, 2010, Volume: 105, Issue:3 Topics: Anticoagulants; Asian People; Aspirin; Cerebral Infarction; Endoscopy, Gastrointestinal; Humans; Ris	2010
Secondary trigeminal neuropathy and neuralgia resulting from pontine infarction. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010, Volume: 19, Issue:3 Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Carbamazepi	2010
Investigation of gastroduodenal mucosal injuries caused by low-dose aspirin therapy in patients with cerebral infarction. Journal of gastroenterology and hepatology, 2010, Volume: 25 Suppl 1 Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Cardiovascular Agents; Cerebral Infarction; Chi	2010
Acute mutism: a useful lesson. Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:1 Topics: Acute Disease; Adult; Aphasia, Broca; Aspirin; Cerebral Infarction; Diagnosis, Differential; Drug Th	2011
Dose-related effect of statins in venous thrombosis risk reduction. The American journal of medicine, 2011, Volume: 124, Issue:9 Topics: Aged; Aspirin; Atherosclerosis; Cerebral Infarction; Clopidogrel; Cohort Studies; Cross-Sectional St	2011
Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model. Stroke, 2012, Volume: 43, Issue:2 Topics: Animals; Aspirin; Brain; Cerebral Hemorrhage; Cerebral Infarction; Cilostazol; Immunohistochemistry;	2012
Potentiation of aspirin-induced cerebroprotection by minocycline: a therapeutic approach to attenuate exacerbation of transient focal cerebral ischaemia. Diabetes & vascular disease research, 2012, Volume: 9, Issue:1 Topics: Animals; Aspirin; Blood Glucose; Blood-Brain Barrier; Body Weight; Brain; Brain Edema; Capillary Per	2012
[Aspirin versus anticoagulation in young patients with cerebral infarction secondary to primary antiphospholipid syndrome]. Revista de neurologia, 2011, Nov-16, Volume: 53, Issue:10 Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Cerebral Infarction; Female; Follow-Up St	2011
Insufficient platelet inhibition is related to silent embolic cerebral infarctions after coronary angiography. Stroke, 2012, Volume: 43, Issue:3 Topics: Aged; Aspirin; Atherosclerosis; Basilar Artery; Carotid Arteries; Cerebral Infarction; Clopidogrel;	2012
Persistence, adherence and outcomes with antiplatelet regimens following cerebral infarction in the Tayside Stroke Cohort. Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 33, Issue:2 Topics: Aged; Aspirin; Cerebral Infarction; Clopidogrel; Cohort Studies; Dipyridamole; Drug Prescriptions; D	2012
Bilateral thalamic infarct caused by spontaneous vertebral artery dissection in pre-eclampsia with HELLP syndrome: a previously unreported association. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2012, Volume: 21, Issue:8 Topics: Adult; Aspirin; Cerebral Angiography; Cerebral Infarction; Female; HELLP Syndrome; Humans; Postpartu	2012
Recurrent cerebral infarction in Klippel-Trenaunay-Weber syndrome. Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:7 Topics: Aspirin; Cerebral Angiography; Cerebral Infarction; Dysarthria; Female; Fibromuscular Dysplasia; Gai	2012
Clinical and pathological improvement in stroke-prone spontaneous hypertensive rats related to the pleiotropic effect of cilostazol. Stroke, 2012, Volume: 43, Issue:6 Topics: Animals; Aspirin; Biomarkers; Cerebral Infarction; Cilostazol; Clopidogrel; Hippocampus; Male; Nerve	2012
Multiple cerebral infarctions related to famotidine-induced eosinophilia. Journal of neurology, 2012, Volume: 259, Issue:10 Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulc	2012
Cerebral infarction due to smoker's polycythemia. BMJ case reports, 2011, Oct-28, Volume: 2011 Topics: Aged; Aspirin; Cerebral Infarction; Diagnosis, Differential; Hematocrit; Humans; Magnetic Resonance	2011
[Platelet inhibition in clinical practice]. Therapeutische Umschau. Revue therapeutique, 2012, Volume: 69, Issue:11 Topics: Aged; Angioplasty, Balloon, Coronary; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Clo	2012
[Risks in atrial fibrillation and simultaneous renal failure]. Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:38 Topics: Aspirin; Atrial Fibrillation; Cerebral Infarction; Comorbidity; Fibrinolytic Agents; Humans; Kidney	2012
[Kawasaki disease complicated with cerebral infarction: a case report]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2012, Volume: 50, Issue:8 Topics: Aspirin; Brain; Cerebral Infarction; Epilepsy; Humans; Immunoglobulins, Intravenous; Infant; Male; M	2012
Association of aspirin resistance with increased stroke severity and infarct size. JAMA neurology, 2013, Volume: 70, Issue:2 Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Infarction; Drug Resistance; Female; Humans; Male; Prospe	2013
[Secondary prevention after stroke. 2 platelet inhibitors are better than one]. MMW Fortschritte der Medizin, 2002, May-09, Volume: 144, Issue:19 Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topic; Dipy	2002
[New US guidelines. Myocardial infarct is now treated more aggressively]. MMW Fortschritte der Medizin, 2002, May-16, Volume: 144, Issue:20 Topics: Angina, Unstable; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Humans; Myoc	2002
Effect of aspirin treatment on serum concentrations of lipoprotein(a) in patients with atherosclerotic diseases. Clinical chemistry, 2002, Volume: 48, Issue:9 Topics: Arteriosclerosis; Aspirin; Cerebral Infarction; Coronary Disease; Female; Humans; Hypolipidemic Agen	2002
[Transient cerebral ischemia--precursors of stroke. Can warning signs be recognized?]. MMW Fortschritte der Medizin, 2003, Feb-13, Volume: 145, Issue:7 Topics: Aspirin; Brain; Carotid Stenosis; Cerebral Infarction; Diagnostic Imaging; Exercise; Humans; Ischemi	2003
[Drug therapy of stroke in the stroke unit. A race against time]. MMW Fortschritte der Medizin, 2003, Feb-13, Volume: 145, Issue:7 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Humans; Intensive Care Units	2003
[Secondary prevention after ischemic stroke]. Praxis, 2003, Mar-26, Volume: 92, Issue:13 Topics: Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Cerebral Infarction; Clinical Trials as	2003
Successful perinatal outcome following recurrent idiopathic cerebrovascular strokes in pregnancy: a case report. Archives of gynecology and obstetrics, 2003, Volume: 268, Issue:3 Topics: Adult; Aspirin; Cerebral Infarction; Delivery, Obstetric; Diagnosis, Differential; Drug Therapy, Com	2003
[How should anticoagulants be used in recurrent, ischemic and hemorrhagic brain infarctions?]. Deutsche medizinische Wochenschrift (1946), 2003, Oct-17, Volume: 128, Issue:42 Topics: Administration, Oral; Age Factors; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Hemo	2003
[Stroke: management]. VASA. Zeitschrift fur Gefasskrankheiten, 2004, Volume: 33, Issue:1 Topics: Aspirin; Cerebral Infarction; Evidence-Based Medicine; Humans; Neuroprotective Agents; Platelet Aggr	2004
Aspirin: it's hard to beat. Neurology, 2004, Apr-13, Volume: 62, Issue:7 Topics: Aspirin; Cerebral Infarction; Humans; Pilot Projects; Platelet Aggregation Inhibitors; Randomized Co	2004
[Diagnosis of acute splenic infarction by echo-signal-enhanced ultrasound]. Deutsche medizinische Wochenschrift (1946), 2004, Apr-16, Volume: 129, Issue:16 Topics: Acute Disease; Adult; Aged; Anticoagulants; Aortic Valve; Aspirin; Cerebral Infarction; Echocardiogr	2004
Diagnosis and treatment of a cerebral infarct in a chimpanzee (Pan troglodytes). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2004, Volume: 35, Issue:2 Topics: Animals; Ape Diseases; Aspirin; Cerebral Infarction; Fibrinolytic Agents; Magnetic Resonance Imaging	2004
[Secondary prevention of TIA and stroke. How much must thrombocytes not be inhibited?]. MMW Fortschritte der Medizin, 2004, Jun-10, Volume: 146, Issue:24 Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Drug Therapy, Combination; Hemo	2004
[For which patient ASS, clopidogrel or dipyridamole? (interview by Dr. Med. Dirk Einecke)]. MMW Fortschritte der Medizin, 2004, Jun-10, Volume: 146, Issue:24 Topics: Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Dipyridamole; Drug Therapy, Com	2004
[Antiplatelet therapy in patients with peripheral arterial disease (PAD)]. Medizinische Klinik (Munich, Germany : 1983), 2004, Aug-15, Volume: 99 Suppl 1 Topics: Arterial Occlusive Diseases; Aspirin; Cause of Death; Cerebral Infarction; Clopidogrel; Coronary Art	2004
[Secondary prevention after ischemic stroke. High risk patients need special protection]. MMW Fortschritte der Medizin, 2004, Volume: 146 Suppl 1 Topics: Arteriosclerosis; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Humans; Intra	2004
[Primary and secondary prevention of stroke. Prevention is better than healing]. MMW Fortschritte der Medizin, 2004, Volume: 146 Suppl 1 Topics: Aged; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy	2004
[ASS plus dipyridamole instead of ASS monotherapy. Risk for second stroke cut in half]. MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28 Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topic; Dela	2004
Lack of antiapoptotic effects of antiplatelet drug, aspirin and clopidogrel, and antioxidant, MCI-186, against focal ischemic brain damage in rats. Neurological research, 2005, Volume: 27, Issue:5 Topics: Animals; Antioxidants; Antipyrine; Aspirin; bcl-2-Associated X Protein; Blotting, Western; Brain Ede	2005
A patient with cerebral Whipple's disease and a stroke-like syndrome. Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:5 Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Diseases; Ceftriaxone	2005
The clinical variability of Wallenberg's syndrome. The anatomical correlate of ipsilateral axial lateropulsion. Journal of neurology, 2006, Volume: 253, Issue:4 Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Brain; Cerebral Infarction; Clopidogrel; Dipyridam	2006
Antiplatelet therapy contributes to acute deterioration of intracerebral hemorrhage. Neurology, 2005, Oct-11, Volume: 65, Issue:7 Topics: Administration, Oral; Aged; Aspirin; Brain Ischemia; Causality; Cerebral Arteries; Cerebral Hemorrha	2005
[Germany's girths in an international comparison]. Krankenpflege Journal, 2005, Volume: 43, Issue:7-10 Topics: Abdominal Fat; Adult; Anthropometry; Aspirin; Aspirin, Dipyridamole Drug Combination; Body Mass Inde	2005
[New DGN-/DSG guidelines]. Krankenpflege Journal, 2005, Volume: 43, Issue:7-10 Topics: Adult; Aspirin; Aspirin, Dipyridamole Drug Combination; Cerebral Infarction; Clinical Trials as Topi	2005
Rotational vertigo associated with parietal cortical infarction. Journal of the neurological sciences, 2006, Jul-15, Volume: 246, Issue:1-2 Topics: Aged; Aspirin; Cerebral Infarction; Electroencephalography; Female; Humans; Intracranial Embolism; M	2006
Pharmacoeconomic analysis of cilostazol for the secondary prevention of cerebral infarction. Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:4 Topics: Aged; Aspirin; Case-Control Studies; Cerebral Infarction; Cilostazol; Cost-Benefit Analysis; Health	2006
Absence epilepsy associated with moyamoya disease. Case report. Journal of neurosurgery, 2006, Volume: 104, Issue:4 Suppl Topics: Anticonvulsants; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Cerebral Angiography; Cerebral	2006
Large subcortical infarcts: clinical features, risk factors, and long-term prognosis compared with cortical and small deep infarcts. Stroke, 2006, Volume: 37, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain; Cerebral Cortex; Cerebral Infarction; Cohort Studies	2006
Previous use of aspirin and baseline stroke severity: an analysis of 17,850 patients in the International Stroke Trial. Stroke, 2006, Volume: 37, Issue:7 Topics: Adult; Aged; Aspirin; Brain Ischemia; Cerebral Infarction; Cohort Studies; Confounding Factors, Epid	2006
Papuloerythroderma caused by aspirin. Archives of dermatology, 2006, Volume: 142, Issue:6 Topics: Aged; Aspirin; Cerebral Infarction; Diagnosis, Differential; Drug Eruptions; Extremities; Humans; Ma	2006
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. Nederlands tijdschrift voor geneeskunde, 2006, Aug-19, Volume: 150, Issue:33 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Humans; Ische	2006
[Treating ischemic stroke as an emergency to prevent cerebral infarction or limit its spread]. La Revue du praticien, 2006, Sep-15, Volume: 56, Issue:13 Topics: Aspirin; Cerebral Infarction; Emergencies; Fibrinolytic Agents; Humans; Ischemic Attack, Transient;	2006
[Prevention of vascular events after transient ischemic attack or cerebral infarct]. La Revue du praticien, 2006, Sep-15, Volume: 56, Issue:13 Topics: Angioplasty, Balloon; Anticoagulants; Aspirin; Cerebral Infarction; Clopidogrel; Dipyridamole; Drug	2006
[Guidelines given by the DSG and DGN concerning stroke therapy--new therapeutic aspects]. Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95 Suppl 6 Topics: Aged; Antihypertensive Agents; Aspirin; Carotid Stenosis; Cerebral Infarction; Combined Modality The	2006
[Subtle, temporary, homonymous visual field defect--fatal causes?]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2007, Volume: 104, Issue:9 Topics: Adult; Anticoagulants; Aspirin; Cerebral Infarction; Fibrinolytic Agents; Foramen Ovale, Patent; Hem	2007
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. Nederlands tijdschrift voor geneeskunde, 2006, Dec-02, Volume: 150, Issue:48 Topics: Aspirin; Cerebral Infarction; Dipyridamole; Headache; Humans; Ischemic Attack, Transient; Platelet A	2006
[The combination of acetylsalicylic acid and dipyridamole is more effective in secondary prevention following transient ischaemic attack or cerebral infarction: the debate is closed]. Nederlands tijdschrift voor geneeskunde, 2006, Dec-02, Volume: 150, Issue:48 Topics: Aspirin; Cerebral Infarction; Dipyridamole; Evidence-Based Medicine; Financial Support; Humans; Isch	2006
Internal carotid artery stenosis with ipsilateral persistent hypoglossal artery presenting as a multiterritorial embolic infarction: a case report. Acta radiologica (Stockholm, Sweden : 1987), 2007, Volume: 48, Issue:1 Topics: Aged; Aspirin; Basilar Artery; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarctio	2007
Elevated platelet microparticle levels in nonvalvular atrial fibrillation: relationship to p-selectin and antithrombotic therapy. Chest, 2007, Volume: 131, Issue:3 Topics: Aged; Aspirin; Atrial Fibrillation; Blood Coagulation Factors; Blood Platelets; Cardiovascular Disea	2007
[The management of stroke in Phnom Penh, Cambodia]. Bulletin de la Societe de pathologie exotique (1990), 2007, Volume: 100, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Calcium Channe	2007
Combination treatment with dipyridamole, aspirin, and tPA in an embolic model of stroke in rats. Experimental neurology, 2007, Volume: 205, Issue:2 Topics: Animals; Aspirin; Brain; Cerebral Infarction; Cerebrovascular Circulation; Dipyridamole; Drug Therap	2007
[Should aspirin be used in secondary prevention of cerebral infarction?]. Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Humans	2007
[Aspirin in secondary prevention of cerebral infarction]. Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Humans	2007
[Late-onset hemorrhagic infarction in patients with patent foramen ovale: reports of two cases]. Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:9 Topics: Acute-Phase Reaction; Aged; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Foramen Ovale, Patent	2007
Familial Moyamoya disease in two European children. Journal of child neurology, 2007, Volume: 22, Issue:12 Topics: Adult; Anticonvulsants; Aspirin; Blood Coagulation Disorders, Inherited; Brain; Cerebral Infarction;	2007
Neuroprotection and glutamate attenuation by acetylsalicylic acid in temporary but not in permanent cerebral ischemia. Experimental neurology, 2008, Volume: 210, Issue:2 Topics: Analysis of Variance; Animals; Aspirin; Brain Ischemia; Cerebral Infarction; Disease Models, Animal;	2008
Carotid occlusion and cerebral infarction from camel bite: case report. East African medical journal, 2007, Volume: 84, Issue:11 Topics: Adult; Animals; Aphasia; Aspirin; Bites and Stings; Camelus; Carotid Arteries; Carotid Artery Diseas	2007
Experimental basis of platelet aggregation inhibition by acetylsalicylic acid. Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:6 Topics: Adenosine Diphosphate; Aspirin; Carotid Artery Thrombosis; Cerebral Infarction; Coronary Circulation	1984
[Problems of the treatment of cerebral infarction]. No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:1 Topics: Aged; Animals; Aspirin; Brain; Cerebral Infarction; Cerebrovascular Circulation; Dextrans; Female; g	1983
Pharmacological studies on OKY-1581: a selective thromboxane synthetase inhibitor. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11 Topics: Acrylates; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Assay; Blood Platelets;	1983
[Blood thromboxane A2 and prostaglandin I2 levels and platelet phospholipid fatty acid composition ratios in ischemic heart disease and cerebral infarction--with special reference to the effect of antiplatelet agents]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1983, Volume: 20, Issue:4 Topics: Aged; Aspirin; Blood Platelets; Cerebral Infarction; Coronary Disease; Dipyridamole; Epoprostenol; F	1983
The significance of carotid stenosis or ulceration. Neurology, 1984, Volume: 34, Issue:4 Topics: Angiography; Arterial Occlusive Diseases; Aspirin; Carotid Artery Diseases; Cerebral Infarction; Fem	1984
The lame brain at the crossroads: which therapeutic road? The New Zealand medical journal, 1984, Apr-25, Volume: 97, Issue:754 Topics: Aged; Aspirin; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; Dipyridamole	1984
The role of the neurologist in the decline of stroke. Annals of neurology, 1983, Volume: 14, Issue:1 Topics: Anticoagulants; Aspirin; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; En	1983
Diagnosis and management of ischemic stroke. Part I.--Threatened stroke and its management. Current problems in cardiology, 1983, Volume: 8, Issue:5 Topics: Anticoagulants; Arrhythmias, Cardiac; Aspirin; Brain Ischemia; Carotid Artery Thrombosis; Cerebral A	1983
[Present status of the therapy of acute cerebral transient ischemic attacks]. Revista medica de Chile, 1983, Volume: 111, Issue:1 Topics: Acute Disease; Aspirin; Carotid Arteries; Cerebral Infarction; Drug Therapy, Combination; Endarterec	1983
Cerebral infarction and migraine. Neurology, 1980, Volume: 30, Issue:4 Topics: Aspirin; Cerebral Infarction; Humans; Migraine Disorders; Propranolol	1980
[Should platelet aggregation inhibitors be given in cerebral ischemic insults?]. Die Medizinische Welt, 1980, Sep-26, Volume: 31, Issue:39 Topics: Aspirin; Cerebral Infarction; Double-Blind Method; Humans; Ischemic Attack, Transient; Platelet Aggr	1980
Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model. Thrombosis research, 1995, Jul-01, Volume: 79, Issue:1 Topics: Animals; Aspirin; Brain Chemistry; Brain Edema; Cerebral Arteries; Cerebral Infarction; Drug Evaluat	1995
Aspirin and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Journal of neurosurgery, 1995, Volume: 82, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Cerebral Infarction; Female	1995
Postvaricella basal ganglia infarction in children. AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:3 Topics: Adrenal Cortex Hormones; Aspirin; Basal Ganglia; Basal Ganglia Diseases; Cerebral Infarction; Chicke	1995
[Thrombocyte function inhibitors in stroke prevention. Ticlopidine as an alternative to acetylsalicylic acid]. Fortschritte der Medizin, 1994, Sep-30, Volume: 112, Issue:27 Topics: Aspirin; Cerebral Infarction; Humans; Intracranial Embolism and Thrombosis; Platelet Aggregation; Ra	1994
Diaspirin crosslinked hemoglobin (DCLHb): effect of hemodilution during focal cerebral ischemia in rats. Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3 Topics: Animals; Aspirin; Blood Substitutes; Blood Volume; Brain Ischemia; Cerebral Infarction; Cerebrovascu	1994
Effect of plasma fibrinogen concentration on the inhibition of platelet aggregation after ticlopidine compared with aspirin. Stroke, 1994, Volume: 25, Issue:10 Topics: Adenosine Diphosphate; Aged; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Collagen; Fema	1994
Patent foramen ovale and brain infarct. Echocardiographic predictors, recurrence, and prevention. Stroke, 1994, Volume: 25, Issue:4 Topics: Adult; Aged; Aspirin; Cerebral Infarction; Cerebrovascular Disorders; Echocardiography, Transesophag	1994
Should cerebral ischemic events in cancer patients be considered a manifestation of hypercoagulability? Stroke, 1994, Volume: 25, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Coagulation Disorders; Brain Ischemia; Cerebral Infar	1994
[Chronic recurrent thrombotic thrombocytopenic purpura (Moschcowitz disease). An unusual long-term course in a 43-year-old patient]. Der Internist, 1993, Volume: 34, Issue:10 Topics: Adult; Aspirin; Biopsy; Cerebral Angiography; Cerebral Infarction; Combined Modality Therapy; Female	1993
Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits. Thrombosis research, 1993, May-01, Volume: 70, Issue:3 Topics: Animals; Aspirin; Carotid Artery Thrombosis; Carotid Stenosis; Cerebral Infarction; Disease Models,	1993
Postpartum cerebral infarction associated with aspirin withdrawal in the antiphospholipid antibody syndrome. The Journal of rheumatology, 1993, Volume: 20, Issue:7 Topics: Adult; Antiphospholipid Syndrome; Aspirin; Cerebral Infarction; Female; Hemiplegia; Humans; Postpart	1993
Fatal hemorrhage during anticoagulation of cardioembolic infarction: role of cerebral amyloid angiopathy. European neurology, 1993, Volume: 33, Issue:1 Topics: Aged; Aspirin; Cerebral Amyloid Angiopathy; Cerebral Cortex; Cerebral Hemorrhage; Cerebral Infarctio	1993
Ischemic stroke, Part 2: Optimal treatment and prevention. Geriatrics, 1993, Volume: 48, Issue:3 Topics: Aged; Aspirin; Brain Edema; Brain Ischemia; Cerebral Infarction; Heparin; Humans; Recurrence; Risk F	1993
The experiences of an acute stroke unit--implications for multicentre acute stroke trials. Journal of neurology, neurosurgery, and psychiatry, 1993, Volume: 56, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Infarction; Clinical Trials as Topic; Eligibility	1993
Carotid pseudovalvular fold: a case diagnosed by angiography and helical cervical tomography. Stroke, 1996, Volume: 27, Issue:5 Topics: Adult; Aphasia; Aspirin; Carotid Artery, Internal; Cerebral Angiography; Cerebral Infarction; Female	1996
Risk of stroke in a cohort of 815 patients with calcification of the aortic valve with or without stenosis. Stroke, 1996, Volume: 27, Issue:5 Topics: Age Factors; Aged; Anticoagulants; Aortic Valve; Aortic Valve Stenosis; Aspirin; Calcinosis; Cause o	1996
[Cerebral infarct in chronic acetylsalicylic acid poisoning]. Der Nervenarzt, 1996, Volume: 67, Issue:4 Topics: Aspirin; Basilar Artery; Blood Coagulation Tests; Brain Stem; Cerebral Angiography; Cerebral Infarct	1996
Effect of oncotic pressure of diaspirin cross-linked hemoglobin (DCLHb) on brain injury after temporary focal cerebral ischemia in rats. Anesthesia and analgesia, 1996, Volume: 83, Issue:2 Topics: Animals; Aspirin; Blood Volume; Brain; Cerebral Infarction; Coloring Agents; Dose-Response Relations	1996
Combined neuroprotection and reperfusion therapy for stroke. Effect of lubeluzole and diaspirin cross-linked hemoglobin in experimental focal ischemia. Stroke, 1996, Volume: 27, Issue:9 Topics: Animals; Aspirin; Cardiovascular Agents; Cerebral Infarction; Cerebrovascular Disorders; Drug Therap	1996
Cerebral infarction and antiphospholipid syndrome in children. The Journal of rheumatology, 1996, Volume: 23, Issue:8 Topics: Adolescent; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Aspirin; Biomarkers; Cerebral In	1996
Hypervolemic-hemodilution during cerebral ischemia in rats: effect of diaspirin cross-linked hemoglobin (DCLHb) on neurologic outcome and infarct volume. Journal of neurosurgical anesthesiology, 1997, Volume: 9, Issue:1 Topics: Animals; Aspirin; Blood Substitutes; Blood Volume; Carotid Artery, External; Cerebral Arteries; Cere	1997
[Recurrent infarct during aspirin therapy]. Der Internist, 1997, Volume: 38, Issue:4 Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Dose-Response Relationship, Drug;	1997
[Anticoagulation for immobilized infarct patients]. Der Internist, 1997, Volume: 38, Issue:4 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Heparin; Humans; Immobiliza	1997
[Secondary prevention of recurrent transient ischemic attacks]. Der Internist, 1998, Volume: 39, Issue:4 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Female; Humans; Ischemic At	1998
[Atrial fibrillation of non-valvular origin and anti-coagulation: a promising opportunity for the prevention of cerebral infarct... if there is participation of those working in primary care]. Revista de neurologia, 1998, Volume: 27, Issue:157 Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Infarction; Humans; Primary Health Care	1998
[On the combination of traditional Chinese medicine and western medicine in the treatment of ischemic apoplexy]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:1 Topics: Aspirin; Cerebral Infarction; Dementia, Multi-Infarct; Drug Therapy, Combination; Drugs, Chinese Her	1997
Neuroprotective effects of acetylsalicylic acid in an animal model of focal brain ischemia. Neuroreport, 1999, Feb-05, Volume: 10, Issue:2 Topics: Animals; Aspirin; Brain; Brain Ischemia; Cerebral Infarction; Male; Neuroprotective Agents; Rats; Ra	1999
[A case of Down syndrome with moyamoya syndrome presenting extensive multiple cerebral infarction during measles infection]. No to hattatsu = Brain and development, 2000, Volume: 32, Issue:1 Topics: Aspirin; Cerebral Infarction; Child, Preschool; Down Syndrome; Humans; Male; Measles; Moyamoya Disea	2000
Moyamoya syndrome with protein S deficiency. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2000, Volume: 4, Issue:4 Topics: Aphasia; Aspirin; Brain; Cerebral Angiography; Cerebral Infarction; Child; Humans; Magnetic Resonanc	2000
[Cost effectiveness of clopidogrel in secondary cardiovascular prevention: a cost-effectiveness analysis based on the Caprie Study]. Praxis, 2001, Mar-29, Volume: 90, Issue:13 Topics: Adult; Aged; Arterial Occlusive Diseases; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Clopido	2001
Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats. Journal of neurochemistry, 2001, Volume: 79, Issue:2 Topics: Adenosine Triphosphate; Animals; Aspirin; Brain; Brain Ischemia; Cerebral Infarction; Excitatory Ami	2001
Technetium-99m-ECD SPECT in antiphospholipid antibody syndrome: a drastic improvement in brain perfusion by antiplatelet therapy. European radiology, 2001, Volume: 11, Issue:12 Topics: Antiphospholipid Syndrome; Aspirin; Cerebral Infarction; Cysteine; Female; Follow-Up Studies; Humans	2001
[Risk improves effectiveness. Proper administration of platelet aggregation inhibitors]. MMW Fortschritte der Medizin, 2002, Mar-14, Volume: 144, Issue:11 Topics: Aspirin; Cerebral Infarction; Clopidogrel; Humans; Myocardial Infarction; Platelet Aggregation Inhib	2002
[Acetylsalicylic acid for cardiovascular risk patients. Placebo or life safer?]. MMW Fortschritte der Medizin, 2002, Mar-14, Volume: 144, Issue:11 Topics: Aspirin; Cerebral Infarction; Humans; Myocardial Infarction; Risk; Survival Rate	2002
[Secondary prophylaxis after cerebral infarction without cardiac source of embolism. Anticoagulants are not better than ASA according to a new extensive trial (WARSS)]. Lakartidningen, 2002, May-16, Volume: 99, Issue:20 Topics: Anticoagulants; Aspirin; Cerebral Infarction; Fibrinolytic Agents; Humans; International Normalized	2002
[Therapy with anticoagulants and platelet aggregation inhibitors in extracranial vascular stenoses and occlusions]. Der Internist, 1979, Volume: 20, Issue:11 Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Cerebrovascular Disorders	1979
Management of the asymptomatic carotid bruit. American heart journal, 1979, Volume: 98, Issue:1 Topics: Aspirin; Auscultation; Carotid Artery Diseases; Cerebral Infarction; Cerebrovascular Disorders; Enda	1979
Prevention of subsequent infarctions and transient ischemic attacks. Advances in neurology, 1979, Volume: 25 Topics: Aged; Anticoagulants; Aspirin; Cerebral Infarction; Humans; Ischemic Attack, Transient; Middle Aged;	1979
Cerebral infarction and migraine. Neurology, 1979, Volume: 29, Issue:10 Topics: Aspirin; Cerebral Infarction; Humans; Migraine Disorders; Propranolol	1979
[Temporary paralysis in a 17-year-old body-builder]. Duodecim; laaketieteellinen aikakauskirja, 1991, Volume: 107, Issue:20 Topics: Adolescent; Anabolic Agents; Animals; Aspirin; Cerebral Infarction; Humans; Male; Paralysis; Tomogra	1991
Urinary 11-dehydro-thromboxane B2: a quantitative index of platelet activation in cerebral infarction. Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:6 Topics: Adult; Aged; Arteriosclerosis; Aspirin; Atrial Fibrillation; Carotid Artery Diseases; Cerebral Infar	1992
Dose-response of rt-PA and its combination with aspirin in a rat embolic stroke model. Neuroreport, 1992, Volume: 3, Issue:10 Topics: Animals; Aspirin; Blood Gas Analysis; Blood Pressure; Carotid Artery Thrombosis; Cerebral Angiograph	1992
[Strategies for antiplatelet therapy-drug-fixed method and suppression-fixed method]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:2 Topics: Aspirin; Cerebral Infarction; Dipyridamole; Drug Therapy, Combination; Humans; Myocardial Infarction	1992
Cerebral ischemia associated with anticardiolipin antibodies. Acta neurologica Scandinavica, 1992, Volume: 85, Issue:6 Topics: Adult; Aged; Antiphospholipid Syndrome; Aspirin; Autoantibodies; Brain Ischemia; Cardiolipins; Cereb	1992
Dysarthria and a numb hand in an elderly woman. Hospital practice (Office ed.), 1992, Jan-15, Volume: 27, Issue:1 Topics: Aged; Aspirin; Cerebral Infarction; Dysarthria; Female; Hand; Hematoma, Subdural; Humans; Paresthesi	1992
[Effect of antiplatelet therapy on prevention of thrombotic diseases]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Jun-10, Volume: 80, Issue:6 Topics: Arachidonic Acid; Arterial Occlusive Diseases; Aspirin; Cerebral Infarction; Humans; Myocardial Infa	1991
[Carotid endarterectomy for prevention of stroke: comparison of surgical and conservative therapy]. Der Nervenarzt, 1991, Volume: 62, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral	1991
Heparin-induced hyperkalemia. Journal of the Tennessee Medical Association, 1991, Volume: 84, Issue:3 Topics: Aged; Aspirin; Cerebral Infarction; Drug Therapy, Combination; Heparin; Humans; Hyperkalemia; Male;	1991
Spasm of the near reflex associated with cerebrovascular accident. Australian and New Zealand journal of ophthalmology, 1990, Volume: 18, Issue:4 Topics: Accommodation, Ocular; Aged; Aspirin; Atropine; Brain Ischemia; Cerebral Infarction; Diplopia; Femal	1990
Mechanism of stroke in patients taking aspirin. Neurology, 1990, Volume: 40, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disord	1990
Patterns of failure of aspirin treatment in symptomatic atherosclerotic carotid artery disease. Neurosurgery, 1990, Volume: 26, Issue:4 Topics: Aged; Arteriosclerosis; Aspirin; Carotid Artery Diseases; Cerebral Infarction; Humans; Middle Aged;	1990
Effect of cilostazol on experimental cerebral infarction in rabbits. Arzneimittel-Forschung, 1986, Volume: 36, Issue:7 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Azoles; Brain; Cerebral Infarction; Cilostazo	1986
Sneddon's syndrome: an antiphospholipid antibody syndrome? Neurology, 1988, Volume: 38, Issue:5 Topics: Antibodies; Aspirin; Blood Coagulation Factors; Cardiolipins; Cerebral Infarction; Dipyridamole; Fem	1988
Cerebral infarction in juvenile rheumatoid arthritis. Clinical neurology and neurosurgery, 1988, Volume: 90, Issue:3 Topics: Arthritis, Juvenile; Aspirin; Cerebral Infarction; Female; Humans; Infant; Phenytoin; Radiography; S	1988
Aspirin, anticoagulants, and hemorrhagic conversion of ischemic infarction: hypothesis and implications. Bulletin of clinical neurosciences, 1986, Volume: 51 Topics: Anticoagulants; Aspirin; Carotid Artery Diseases; Cerebral Hemorrhage; Cerebral Infarction; Heparin;	1986
[Remote development of transient ischemic attack, reversible ischemic neurologic deficit and infarct with minimum residual damage. Prospective study of 149 patients treated medically]. Medicina clinica, 1987, Sep-12, Volume: 89, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Brain Ischemia; Cerebral Infarction; Female	1987
Cerebral infarct after an overdose of anti-cold medicines. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Feb-15, Volume: 69, Issue:4 Topics: Adult; Aspirin; Cerebral Infarction; Female; Humans; Vasoconstrictor Agents	1986
Carotid endarterectomy. One solution to the stroke problem. The American surgeon, 1985, Volume: 51, Issue:2 Topics: Adult; Aged; Arterial Occlusive Diseases; Aspirin; Carotid Arteries; Carotid Artery Diseases; Cerebr	1985
[Late hemorrhagic transformation of cerebellar infarction under anticoagulant treatment]. Revue neurologique, 1985, Volume: 141, Issue:4 Topics: Anticoagulants; Aspirin; Cerebellum; Cerebral Hemorrhage; Cerebral Infarction; Humans; Male; Middle	1985
[Duration of the effect of acetylsalicylic acid on circulating platelet aggregates in cerebral infarct patients]. Fortschritte der Neurologie-Psychiatrie, 1985, Volume: 53, Issue:9 Topics: Adult; Aged; Aspirin; Cerebral Infarction; Female; Humans; Male; Middle Aged; Platelet Aggregation;	1985
[Diagnosis of platelet function with polymerized insoluble collagen]. VASA. Zeitschrift fur Gefasskrankheiten, 1985, Volume: 14, Issue:3 Topics: Adult; Aspirin; Cerebral Infarction; Collagen; Female; Humans; Male; Middle Aged; Platelet Aggregati	1985
[Medical treatment of ischemic cerebrovascular disease]. Duodecim; laaketieteellinen aikakauskirja, 1985, Volume: 101, Issue:22 Topics: Anticoagulants; Aspirin; Brain Ischemia; Cerebral Infarction; Humans; Ischemic Attack, Transient; Pl	1985