Page last updated: 2024-10-22

aspirin and Anovulation

aspirin has been researched along with Anovulation in 4 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Anovulation: Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.

Research Excerpts

ExcerptRelevanceReference
"Among women with a single, recent pregnancy loss, daily preconception low-dose aspirin (LDA) increased the live birth rate with no effect on pregnancy loss."9.24Low-Dose Aspirin and Sporadic Anovulation in the EAGeR Randomized Trial. ( Chen, Z; Galai, N; Lesher, LL; Mumford, SL; Perkins, NJ; Radin, RG; Schisterman, EF; Silver, RM; Sjaarda, LA; Wactawski-Wende, J, 2017)
"To evaluate the efficacy of co-administration of low-dose aspirin (LDA) and tamoxifen on ovulation rates, endometrial thickness and clinical pregnancy rates in anovulatory PCOS women."5.30A new look at low-dose aspirin: Co-administration with tamoxifen in ovulation induction in anovulatory PCOS women. ( Ahmed, MR; Ahmed, WAS; Aref, NK; Sedik, WF, 2019)
"Among women with a single, recent pregnancy loss, daily preconception low-dose aspirin (LDA) increased the live birth rate with no effect on pregnancy loss."5.24Low-Dose Aspirin and Sporadic Anovulation in the EAGeR Randomized Trial. ( Chen, Z; Galai, N; Lesher, LL; Mumford, SL; Perkins, NJ; Radin, RG; Schisterman, EF; Silver, RM; Sjaarda, LA; Wactawski-Wende, J, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aref, NK1
Ahmed, WAS1
Ahmed, MR1
Sedik, WF1
Matyas, RA1
Mumford, SL2
Schliep, KC1
Ahrens, KA1
Sjaarda, LA2
Perkins, NJ2
Filiberto, AC1
Mattison, D1
Zarek, SM1
Wactawski-Wende, J2
Schisterman, EF2
Radin, RG1
Silver, RM1
Chen, Z1
Lesher, LL1
Galai, N1
Espín López, L1
Carrillo Verdejo, E1
González Javier, F1
Ordoñana Martín, JR1
Gómez-Amor, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Aspirin in Gestation and Reproduction: A Multi-center, Controlled, Double-blind Randomized Trial.[NCT00467363]1,228 participants (Actual)Interventional2007-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Abruption

Partial or complete abruption (ie, premature separation of the placenta) (NCT00467363)
Timeframe: until delivery

Interventionparticipants (Number)
Aspirin7
Placebo5

Clinically Recognized Pregnancy

(NCT00467363)
Timeframe: 8-weeks

Interventionpregnancy (Number)
Aspirin374
Placebo346

Early Pregnancy Loss (EPL)

Implantation failures (NCT00467363)
Timeframe: 8 weeks

Interventionpregnancy (Number)
Aspirin28
Placebo27

Ectopic Pregnancy

(NCT00467363)
Timeframe: within 6 weeks

Interventionpregnancy (Number)
Aspirin3
Placebo3

Fetal Pregnancy Loss

(NCT00467363)
Timeframe: until 40 weeks

Interventionpregnancy (Number)
Aspirin4
Placebo6

hCG Recognized Pregnancy

(NCT00467363)
Timeframe: within 8-weeks of gestation

Interventionpregnancy (Number)
Aspirin394
Placebo363

Live Birth

Live birth was obtained prospectively by maternal report and abstraction from medical records by trained staff . (NCT00467363)
Timeframe: after delivery

Interventionlivebirths (Number)
Aspirin309
Placebo286

Molar Pregnancy

(NCT00467363)
Timeframe: 8 weeks

Interventionpregnancy (Number)
Aspirin0
Placebo0

Preeclampsia

(NCT00467363)
Timeframe: until delivery

Interventionparticipants (Number)
Aspirin32
Placebo30

Pregnancy Losses Occurring Less Than 10 Weeks

Includes preembryonic and embryonic losses (exclusive of implantation failures) (NCT00467363)
Timeframe: less than 10-weeks

Interventionpregnancy (Number)
Aspirin56
Placebo53

Preterm Birth

(NCT00467363)
Timeframe: until delivery

Interventioninfants (Number)
Aspirin22
Placebo31

Small for Gestational Age Infant

birthweight (NCT00467363)
Timeframe: until delivery

Interventiongrams (Mean)
Aspirin3327
Placebo3315

Stillbirth

(NCT00467363)
Timeframe: 40 weeks

Interventionparticipants (Number)
Aspirin2
Placebo2

Trials

2 trials available for aspirin and Anovulation

ArticleYear
A new look at low-dose aspirin: Co-administration with tamoxifen in ovulation induction in anovulatory PCOS women.
    Journal of gynecology obstetrics and human reproduction, 2019, Volume: 48, Issue:8

    Topics: Adult; Anovulation; Aspirin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Egypt; End

2019
Low-Dose Aspirin and Sporadic Anovulation in the EAGeR Randomized Trial.
    The Journal of clinical endocrinology and metabolism, 2017, 01-01, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Anovulation; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Humans; Liv

2017

Other Studies

2 other studies available for aspirin and Anovulation

ArticleYear
Effects of over-the-counter analgesic use on reproductive hormones and ovulation in healthy, premenopausal women.
    Human reproduction (Oxford, England), 2015, Volume: 30, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anovulation; Aspirin; Female; Follicular

2015
Incidence of anovulatory menstrual cycles among dysmenorrheic and non-non-dysmenorrheic [corrected] women: effects on symptomatology and mood.
    Psicothema, 2010, Volume: 22, Issue:4

    Topics: Adolescent; Affect; Amenorrhea; Anovulation; Aspirin; Body Temperature; Comorbidity; Dizziness; Dysm

2010