aspirin has been researched along with Amyloid Deposits in 5 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin is a widely used drug throughout the world and recent studies have identified a new function of this drug." | 2.61 | PPARα Between Aspirin and Plaque Clearance. ( Chandra, S; Pahan, K; Patel, DR; Roy, A, 2019) |
| " Chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin for arthritis decreases the risk of developing Alzheimer's disease (AD) by unknown mechanisms." | 1.31 | Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation. ( Nadackal, TG; Thomas, K; Thomas, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chandra, S | 2 |
| Roy, A | 2 |
| Patel, DR | 1 |
| Pahan, K | 3 |
| Patel, D | 1 |
| Jana, M | 1 |
| Melo, HM | 1 |
| Thomas, T | 1 |
| Nadackal, TG | 1 |
| Thomas, K | 1 |
2 reviews available for aspirin and Amyloid Deposits
| Article | Year |
|---|---|
PPARα Between Aspirin and Plaque Clearance.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Plaque, Amyloid; PPAR alpha; Prot | 2019 |
PPARα serves as a new receptor of aspirin for neuroprotection.
Topics: Alzheimer Disease; Animals; Aspirin; Brain; Humans; Neuronal Plasticity; Neurons; Neuroprotective Ag | 2020 |
3 other studies available for aspirin and Amyloid Deposits
| Article | Year |
|---|---|
Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal | 2018 |
Potential Effects of Aspirin on Lysosomal Biogenesis and Amyloid-β Clearance: An Old Drug and Novel Insights in Alzheimer's Disease Therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspirin; Lysosomes; Mice; Plaque, Amyloid; PPAR a | 2019 |
Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxi | 2001 |