Page last updated: 2024-10-23

aspirin and Amaurosis

aspirin has been researched along with Amaurosis in 37 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The ETDRS was a randomized clinical trial investigating photocoagulation and aspirin in 3,711 persons with mild to severe nonproliferative or early proliferative diabetic retinopathy."5.09Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS report no. 24. Early Treatment Diabetic Retinopathy Study Research Group. ( Chew, EY; Davis, MD; Ferris, FL; Fong, DS, 1999)
" Aspirin effectively abolished SPA in 50 patients and relieved the clinical symptoms of patients with recurrent complaints of transient blindness and paraesthesia."3.66Spontaneous platelet aggregation in cerebrovascular disease. ( Jenkins, CS; Oosterhuis, H; Prenger, D; ten Cate, JW; Vos, J, 1978)
"The aspirin effect was the same across all risk-factor groups."2.66Controlled trial of aspirin in cerebral ischemia: an addendum. ( Fields, WS; Gary, HE; Lemak, NA, 1986)
"Four patients presented transient ischemic attacks, one amaurosis fugax, two suffered from a minor stroke, four had non-focalized ischemic cerebral symptoms and two were asymptomatic."2.40Fibromuscular dysplasia of the internal carotid artery. Personal experience with 13 cases and literature review. ( Limet, R; Sakalihasan, N; Van Damme, H, 1999)
"In children and young adults, amaurosis fugax is a benign condition."2.38Atherosclerotic carotid disease and the eye. ( Breen, LA, 1991)
"Transient ischemic attacks are associated with a 30 to 35 percent risk of stroke within five years of the initial episode."2.37Carotid surgery in stroke prevention. ( Busuttil, RW; Sheng, FC, 1986)
"Takayasu arteritis is a granulomatous panarteritis that predominantly affects the aorta and its major branches."1.46Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report. ( Epafra, E; Janabi, M; Kazahura, P; Lyimo, F; Nicholaus, P; Pallangyo, P, 2017)
"Giant cell arteritis (GCA) or temporal arteritis (TA) with polymyalgia rheumatica (PMR) is among the most common reasons for long-term steroid prescription."1.36Concise guidance: diagnosis and management of giant cell arteritis. ( Dasgupta, B, 2010)
"Systematic search for the cause of branch retinal artery occlusion revealed Factor V Leiden mutation and antiphospholipid antibody syndrome as the cause."1.32Sudden painless unilateral vision loss caused by branch retinal artery occlusion: implications for the primary care physician. ( Delarosa, M; Harvey, R; Kondamudi, N; Kondamudi, V; Reddy, R, 2004)
" While steroid dosage was gradually decreased, administration of acetylsalicylic acid (for three months 100 mg daily, then three times daily 100 mg) brought about complete disappearance of the visual signs."1.28[The antiphospholipid syndrome. The neurological complications and the therapeutic possibilities]. ( Berg, PA; Leo-Kottler, B; Weller, M; Wiethölter, H, 1991)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199016 (43.24)18.7374
1990's9 (24.32)18.2507
2000's6 (16.22)29.6817
2010's5 (13.51)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Yang, Y1
Qidwai, U1
Burton, BJL1
Canepa, C1
Pallangyo, P1
Epafra, E1
Nicholaus, P1
Lyimo, F1
Kazahura, P1
Janabi, M1
He, MS1
Sheu, MM1
Huang, ZL1
Tsai, CH1
Tsai, RK1
Ryder, SJ1
Oliveira, C1
Dinkin, MJ1
DʼAmico, DJ1
Orlin, A1
Haug, SJ1
Lu, CW1
Wang, J1
Zhou, DD1
Hao, JL1
Liang, LL1
Li, XH1
Hui, P1
Borg, FA1
Dasgupta, B2
Welchering, T1
Kondamudi, V1
Reddy, R1
Kondamudi, N1
Harvey, R1
Delarosa, M1
Hellmann, DB1
Nesher, G1
Berkun, Y1
Mates, M1
Baras, M1
Rubinow, A1
Sonnenblick, M1
Bogousslavsky, J1
Regli, F1
Rousselle, J1
Schmidt, PM1
Gans, M1
Anderson, D1
Hobson, RW1
Weiss, DG1
Fields, WS2
Goldstone, J1
Moore, WS1
Towne, JB1
Wright, CB1
Lee, AG1
González-Gay, MA1
García-Porrúa, C1
Brañas, F1
Fong, DS1
Ferris, FL1
Davis, MD1
Chew, EY1
Van Damme, H1
Sakalihasan, N1
Limet, R1
Pastor, JC1
Baílez, C1
Aragón, J1
Rodríguez de la Rúa, E1
ten Cate, JW1
Vos, J1
Oosterhuis, H1
Prenger, D1
Jenkins, CS1
Duncan, GW1
Pessin, MS1
Mohr, JP1
Adams, RD1
Altman, R1
Boullon, F1
Rouvier, J1
Raca, R1
de la Fuente, L1
Favaloro, R1
Genton, E1
Gent, M1
Hirsh, J1
Harker, LA1
Weller, M1
Leo-Kottler, B1
Berg, PA1
Wiethölter, H1
Breen, LA1
Wiebers, DO1
Swanson, JW1
Cascino, TL1
Whisnant, JP1
Becker, WL1
Burde, RM1
Sheng, FC1
Busuttil, RW1
Lemak, NA1
Gary, HE1
Beck, RW1
Harrison, MJ1
Marshall, J1
Meadows, JC1
Russell, RW1
Mundall, J2
Von Kaulla, KN2
Austin, JH1
Frisén, L1
Didisheim, P1
Kazmier, FJ1
Fuster, V1
Naess, K1
Quintero, P1
Harmon, R1
Austin, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neovascularization Induced by Mechanical Barrier disrUption and Systemic Erythropoietin in Patients With Cerebral Perfusion Deficits (NIMBUS Trial)[NCT02603406]Phase 244 participants (Actual)Interventional2016-07-15Completed
Slow-Release Dexamethasone in Reducing Proliferative Vitreoretinopathy After Vitreotomy in Proliferative Diabetic Retinopathy[NCT05415826]30 participants (Anticipated)Interventional2022-06-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for aspirin and Amaurosis

ArticleYear
Low-dose aspirin in the treatment of giant cell arteritis.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:4

    Topics: Aspirin; Blindness; Giant Cell Arteritis; Humans; Ischemia; Platelet Aggregation Inhibitors

2004
Fibromuscular dysplasia of the internal carotid artery. Personal experience with 13 cases and literature review.
    Acta chirurgica Belgica, 1999, Volume: 99, Issue:4

    Topics: Aged; Aneurysm; Angioplasty, Balloon; Aspirin; Blindness; Brain Ischemia; Carotid Artery Diseases; C

1999
[Treatment of the massive suprachoroidal hemorrhages].
    Archivos de la Sociedad Espanola de Oftalmologia, 2001, Volume: 76, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blindness; Cataract Extraction; Comor

2001
Transient cerebral ischemic attacks.
    Advances in internal medicine, 1976, Volume: 21

    Topics: Anticoagulants; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blindn

1976
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
    The New England journal of medicine, 1975, Dec-04, Volume: 293, Issue:23

    Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso

1975
Atherosclerotic carotid disease and the eye.
    Neurologic clinics, 1991, Volume: 9, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Blindness; Carotid Artery Diseas

1991
Current management of amaurosis fugax. The Amaurosis Fugax Study Group.
    Stroke, 1990, Volume: 21, Issue:2

    Topics: Aspirin; Blindness; Carotid Arteries; Carotid Artery Diseases; Cerebrovascular Disorders; Constricti

1990
Carotid surgery in stroke prevention.
    American family physician, 1986, Volume: 33, Issue:4

    Topics: Aged; Arteriosclerosis; Aspirin; Blindness; Carotid Arteries; Carotid Artery Diseases; Cerebrovascul

1986
Platelet inhibition in the management of thrombosis.
    Thrombosis et diathesis haemorrhagica, 1974, Sep-30, Volume: 32, Issue:1

    Topics: Aspirin; Blindness; Blood Platelets; Cell Survival; Cerebrovascular Disorders; Dextrans; Dipyridamol

1974

Trials

4 trials available for aspirin and Amaurosis

ArticleYear
Efficacy of carotid endarterectomy for asymptomatic carotid stenosis. The Veterans Affairs Cooperative Study Group.
    The New England journal of medicine, 1993, Jan-28, Volume: 328, Issue:4

    Topics: Adult; Aspirin; Blindness; Carotid Arteries; Carotid Stenosis; Cerebrovascular Disorders; Endarterec

1993
Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS report no. 24. Early Treatment Diabetic Retinopathy Study Research Group.
    American journal of ophthalmology, 1999, Volume: 127, Issue:2

    Topics: Aspirin; Blindness; Diabetic Retinopathy; Female; Humans; Laser Coagulation; Male; Middle Aged; Reti

1999
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (first of three parts).
    The New England journal of medicine, 1975, Dec-04, Volume: 293, Issue:23

    Topics: Animals; Antidepressive Agents, Tricyclic; Aspirin; Blindness; Blood Platelets; Cerebrovascular Diso

1975
Controlled trial of aspirin in cerebral ischemia: an addendum.
    Neurology, 1986, Volume: 36, Issue:5

    Topics: Aspirin; Blindness; Carotid Artery Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Di

1986

Other Studies

25 other studies available for aspirin and Amaurosis

ArticleYear
Bilateral, vertical supranuclear gaze palsy following unilateral midbrain infarct.
    BMJ case reports, 2020, Nov-04, Volume: 13, Issue:11

    Topics: Aspirin; Atrial Fibrillation; Betacoronavirus; Blindness; Brain Stem Infarctions; Coronavirus Infect

2020
Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report.
    Journal of medical case reports, 2017, Jun-10, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Blindness; Computed Tomography Angiography; Dexamethasone; Female

2017
Sudden bilateral vision loss and brain infarction following cosmetic hyaluronic acid injection.
    JAMA ophthalmology, 2013, Volume: 131, Issue:9

    Topics: Acetazolamide; Antihypertensive Agents; Aspirin; Blindness; Cerebral Infarction; Cosmetic Techniques

2013
Diagnostic and Therapeutic Challenges.
    Retina (Philadelphia, Pa.), 2016, Volume: 36, Issue:1

    Topics: Adolescent; Aspirin; Blindness; Eye Injuries; Fluorescein Angiography; Humans; Hyperbaric Oxygenatio

2016
Central retinal artery occlusion associated with persistent truncus arteriosus and single atrium: a case report.
    BMC ophthalmology, 2015, Oct-19, Volume: 15

    Topics: Aspirin; Blindness; Echocardiography; Female; Fluorescein Angiography; Heart Atria; Humans; Hyperbar

2015
Giant cell arteritis: not just a stroke in the eye.
    British journal of hospital medicine (London, England : 2005), 2008, Volume: 69, Issue:11

    Topics: Aspirin; Blindness; Drug Therapy, Combination; Early Diagnosis; Giant Cell Arteritis; Glucocorticoid

2008
[A rare disease with varied manifestations. Here threaten blindness, stroke, myocardial infarction].
    MMW Fortschritte der Medizin, 2009, Dec-10, Volume: 151, Issue:51-52

    Topics: Aged; Aspirin; Biopsy; Blindness; Female; Humans; Myocardial Infarction; Platelet Aggregation Inhibi

2009
Concise guidance: diagnosis and management of giant cell arteritis.
    Clinical medicine (London, England), 2010, Volume: 10, Issue:4

    Topics: Aspirin; Blindness; Diagnosis, Differential; Diagnostic Imaging; Early Diagnosis; Giant Cell Arterit

2010
Sudden painless unilateral vision loss caused by branch retinal artery occlusion: implications for the primary care physician.
    The American journal of the medical sciences, 2004, Volume: 327, Issue:1

    Topics: Administration, Oral; Aspirin; Blindness; Eye; Factor V; Heparin; Humans; Injections, Intravenous; M

2004
Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Blindness; Drug Therapy, Combination; Fe

2004
[Cerebrovascular complications of thrombocytosis].
    Schweizerische medizinische Wochenschrift, 1983, Apr-09, Volume: 113, Issue:14

    Topics: Aged; Aspirin; Blindness; Cerebellar Diseases; Cerebellopontine Angle; Facial Paralysis; Female; Hum

1983
Amaurosis fugax: prognosis and the role of acetylsalicylic acid.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1994, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Blindness; Brain Ischemia; Cerebrovascular Disorders; Female; Foll

1994
Reversible loss of vision due to posterior ischemic optic neuropathy.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1995, Volume: 30, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blindness

1995
Carotid occlusion mimicking giant cell arteritis.
    The Journal of rheumatology, 1998, Volume: 25, Issue:6

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blindness; Captopril; Carotid Artery Diseas

1998
Spontaneous platelet aggregation in cerebrovascular disease.
    Thrombosis and haemostasis, 1978, Feb-28, Volume: 39, Issue:1

    Topics: Adenosine; Adenosine Diphosphate; Adult; Aged; Aspirin; Blindness; Brain Diseases; Female; Humans; I

1978
Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves.
    The Journal of thoracic and cardiovascular surgery, 1976, Volume: 72, Issue:1

    Topics: Acenocoumarol; Anticoagulants; Aspirin; Blindness; Drug Therapy, Combination; Female; Gastrointestin

1976
[The antiphospholipid syndrome. The neurological complications and the therapeutic possibilities].
    Deutsche medizinische Wochenschrift (1946), 1991, Nov-22, Volume: 116, Issue:47

    Topics: Adult; Antibodies; Antiphospholipid Syndrome; Aspirin; Blindness; Female; Humans; Nervous System Dis

1991
Bilateral loss of vision in bright light.
    Stroke, 1989, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Blindness; Carotid Artery Diseases; Carotid Artery, External; Caro

1989
Carotid artery disease. A therapeutic enigma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:1

    Topics: Aspirin; Blindness; Carotid Artery Diseases; Cerebrovascular Disorders; Endarterectomy; Eye Diseases

1988
Amaurosis fugax: controversies in management.
    International ophthalmology clinics, 1986,Winter, Volume: 26, Issue:4

    Topics: Adult; Age Factors; Anticoagulants; Aspirin; Blindness; Blood Platelets; Diagnosis, Differential; En

1986
Effect of aspirin in amaurosis fugax.
    Lancet (London, England), 1971, Oct-02, Volume: 2, Issue:7727

    Topics: Aspirin; Blindness; Dipyridamole; Recurrence; Retinal Vessels; Thrombosis

1971
Effect of aspirin in amaurosis fugax.
    Lancet (London, England), 1972, Jan-08, Volume: 1, Issue:7741

    Topics: Aspirin; Blindness; Female; Humans; Middle Aged; Platelet Adhesiveness

1972
[Amaurosis fugax--differential diagnosis and treatment].
    Lakartidningen, 1974, Jul-24, Volume: 71, Issue:30

    Topics: Anticoagulants; Aspirin; Blindness; Cerebrovascular Disorders; Diagnosis, Differential; Humans; Migr

1974
[Aspirin in the treatment of amaurosis. Before or after?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Feb-10, Volume: 92, Issue:4

    Topics: Aspirin; Blindness; Dextrans; Humans; Pulmonary Embolism; Thrombophlebitis

1972
Transient monocular blindness and increased platelet aggregability treated with aspirin. A case report.
    Neurology, 1972, Volume: 22, Issue:3

    Topics: Aspirin; Blindness; Blood Platelet Disorders; Cerebral Angiography; Electroencephalography; Embolism

1972