Page last updated: 2024-10-23

aspirin and Alveolar Bone Atrophy

aspirin has been researched along with Alveolar Bone Atrophy in 8 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Periodontitis is a common chronic inflammatory disease caused by bacteria which can result in periodontal tissue inflammation, as well as alveolar bone resorption."5.51Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats. ( Heo, SM; Li, L; Soh, Y; Yang, M, 2019)
"Clopidogrel but not aspirin showed the ability of preventing bone loss in experimental periodontitis."3.80Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease. ( Coimbra, LS; Muscará, MN; Rossa, C; Spolidorio, LC; Steffens, JP, 2014)
" Ligatures were removed after 10 days of periodontitis induction and all groups were submitted to treatment with aspirin (Asp) (30 mg/kg), clopidogrel (Clop) (75 mg/kg) or NaCl 0."3.80Clopidogrel enhances periodontal repair in rats through decreased inflammation. ( Coimbra, LS; Graves, DT; Rossa, C; Spolidorio, LC; Steffens, JP, 2014)
"To measure the effects on periodontitis, ligatures were placed around first molars, and aspirin (Asp, 30 mg/kg) or clopidogrel (Clo, 75 mg/kg) was given intragastrically once daily for 15 days."3.77Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats. ( Coimbra, LS; Gerlach, RF; Guimarães, MR; Herrera, BS; Muscará, MN; Rossa, C; Spolidorio, DM; Spolidorio, LC, 2011)
"Periodontitis is a common chronic inflammatory disease caused by bacteria which can result in periodontal tissue inflammation, as well as alveolar bone resorption."1.51Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats. ( Heo, SM; Li, L; Soh, Y; Yang, M, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, J1
Mei, S1
Guo, L1
Su, Y1
Wang, H1
Liu, Y2
Zhao, Z1
Wang, S1
Yang, M1
Li, L1
Soh, Y1
Heo, SM1
Coimbra, LS3
Steffens, JP2
Muscará, MN2
Rossa, C3
Spolidorio, LC3
Graves, DT1
Guimarães, MR1
Gerlach, RF1
Spolidorio, DM1
Herrera, BS1
Zigdon, H1
Levin, L1
Filatov, M1
Oettinger-Barak, O1
Machtei, EE1
Arias, OR1
Marquez-Orozco, MC1
Van Dyke, TE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Nonrandomized, Study Comparing the Use of Aspirin and Intraoperative Blood Loss and Postoperative Complications Following Open Inguinal Hernia Repair.[NCT02084615]300 participants (Anticipated)Interventional2014-08-31Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspirin and Alveolar Bone Atrophy

ArticleYear
Control of inflammation and periodontitis.
    Periodontology 2000, 2007, Volume: 45

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Aspirin; Biofilms; Bone Regeneration; Disease

2007

Other Studies

7 other studies available for aspirin and Alveolar Bone Atrophy

ArticleYear
Platelet-rich fibrin/aspirin complex promotes alveolar bone regeneration in periodontal defect in rats.
    Journal of periodontal research, 2018, Volume: 53, Issue:1

    Topics: Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bon

2018
Effects of omega-3 fatty acids and aspirin on Porphyromonas gingivalis-induced periodontitis in rats.
    Journal of periodontology, 2019, Volume: 90, Issue:11

    Topics: Alveolar Bone Loss; Animals; Aspirin; Fatty Acids, Omega-3; Interleukin-1beta; Male; Periodontitis;

2019
Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease.
    Journal of periodontal research, 2014, Volume: 49, Issue:6

    Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Collagen; Connective Ti

2014
Clopidogrel enhances periodontal repair in rats through decreased inflammation.
    Journal of clinical periodontology, 2014, Volume: 41, Issue:3

    Topics: Alveolar Bone Loss; Animals; Aspirin; Cell Count; Chemokine CCL5; Chemokine CXCL12; Clopidogrel; Inf

2014
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
    Journal of periodontology, 2011, Volume: 82, Issue:5

    Topics: Alveolar Bone Loss; Animals; Aspirin; Blood Platelets; Bone Density; Bone Regeneration; Clopidogrel;

2011
Intraoperative bleeding during open flap debridement and regenerative periodontal surgery.
    Journal of periodontology, 2012, Volume: 83, Issue:1

    Topics: Adult; Age Factors; Aged; Alveolar Bone Loss; Anesthetics, Local; Aspirin; Blood Loss, Surgical; Bon

2012
Aspirin, acetaminophen, and ibuprofen: their effects on orthodontic tooth movement.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2006, Volume: 130, Issue:3

    Topics: Acetaminophen; Alveolar Bone Loss; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anti-Inf

2006