aspirin has been researched along with Altitude Hypoxia in 14 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Altitude Hypoxia: Low ambient oxygen tension associated with ALTITUDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of aspirin for headache when exercising during acute high-altitude exposure." | 9.09 | Effects of aspirin during exercise on the incidence of high-altitude headache: a randomized, double-blind, placebo-controlled trial. ( Burtscher, M; Lämmle, T; Likar, R; Nachbauer, W; Philadelphy, M; Pühringer, R, 2001) |
| "Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines." | 7.96 | Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia. ( Feng, Q; Li, W; Sun, Y; Wang, R; Zhang, J; Zhao, A, 2020) |
| "To evaluate the efficacy of aspirin for headache when exercising during acute high-altitude exposure." | 5.09 | Effects of aspirin during exercise on the incidence of high-altitude headache: a randomized, double-blind, placebo-controlled trial. ( Burtscher, M; Lämmle, T; Likar, R; Nachbauer, W; Philadelphy, M; Pühringer, R, 2001) |
| "Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines." | 3.96 | Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia. ( Feng, Q; Li, W; Sun, Y; Wang, R; Zhang, J; Zhao, A, 2020) |
| "Intraretinal hemorrhages in both eyes and a scotoma in the left eye were found." | 1.30 | High-altitude retinopathy. ( Kuba, GB; Lang, GE, 1997) |
| " The regime used was spironolactone in a dosage of 25 mg three times a day for two days preceding and during the periods spent at altitudes above 3,000 m." | 1.26 | Spironolactone and acute mountain sickness. ( Carter, PH; Champion, WL; Currie, TT; Fong, G; Francis, JK; McDonald, IH; Newing, RK; Nunn, IN; Sisson, RN; Sussex, M; Zacharin, RF, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 1 |
| Zhang, J | 1 |
| Zhao, A | 1 |
| Li, W | 1 |
| Feng, Q | 1 |
| Wang, R | 1 |
| Lopez, JI | 1 |
| Holdridge, A | 1 |
| Mendizabal, JE | 1 |
| Basnyat, B | 1 |
| Gertsch, JH | 1 |
| Holck, PC | 1 |
| SUBBA, PS | 1 |
| Wu, T | 1 |
| Liu, J | 1 |
| Kayser, B | 1 |
| Hulsebosch, R | 1 |
| Bosch, F | 1 |
| Berghold, F | 1 |
| Schobersberger, W | 1 |
| Bielenberg, J | 1 |
| Lang, GE | 1 |
| Kuba, GB | 1 |
| Burtscher, M | 2 |
| Likar, R | 2 |
| Nachbauer, W | 2 |
| Philadelphy, M | 2 |
| Pühringer, R | 1 |
| Lämmle, T | 1 |
| Currie, TT | 1 |
| Carter, PH | 1 |
| Champion, WL | 1 |
| Fong, G | 1 |
| Francis, JK | 1 |
| McDonald, IH | 1 |
| Newing, RK | 1 |
| Nunn, IN | 1 |
| Sisson, RN | 1 |
| Sussex, M | 1 |
| Zacharin, RF | 1 |
| Wohns, RN | 1 |
3 reviews available for aspirin and Altitude Hypoxia
| Article | Year |
|---|---|
Altitude headache.
Topics: Acute Disease; Adaptation, Physiological; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Asp | 2013 |
[Etiology, clinical aspects and therapy of altitude sickness].
Topics: Acclimatization; Acetazolamide; Altitude Sickness; Aspirin; Calcium Channel Blockers; Combined Modal | 1994 |
[Altitude sickness].
Topics: Acclimatization; Altitude Sickness; Analgesics; Aspirin; Humans; Oxygen | 1996 |
3 trials available for aspirin and Altitude Hypoxia
| Article | Year |
|---|---|
Low-dose acetylsalicylic acid analog and acetazolamide for prevention of acute mountain sickness.
Topics: Acetazolamide; Acute Disease; Adult; Altitude Sickness; Aspirin; Carbonic Anhydrase Inhibitors; Coho | 2008 |
Aspirin for prophylaxis against headache at high altitudes: randomised, double blind, placebo controlled trial.
Topics: Adult; Altitude Sickness; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Fem | 1998 |
Effects of aspirin during exercise on the incidence of high-altitude headache: a randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Altitude; Altitude Sickness; Aspirin; Double-Blind Method; Exercise; Female; H | 2001 |
8 other studies available for aspirin and Altitude Hypoxia
| Article | Year |
|---|---|
Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia.
Topics: Altitude; Altitude Sickness; Animals; Aspirin; Feces; Gastrointestinal Microbiome; Hypoxia; Rats; Ra | 2020 |
Low-dose acetylsalicylic Acid analog and acetazolamide for prevention of acute mountain sickness.
Topics: Acetazolamide; Acute Disease; Altitude Sickness; Aspirin; Dose-Response Relationship, Drug; Headache | 2008 |
CONTROL OF ACUTE MOUNTAIN SICKNESS.
Topics: Altitude Sickness; Anabolic Agents; Aspirin; Biomedical Research; Drug Therapy; Humans; Hypoxia; Met | 1964 |
Alcohol and aspirin in combination with dexamethasone causes gastrointestinal bleeding at high altitude.
Topics: Adult; Alcohol Drinking; Altitude; Altitude Sickness; Aspirin; Dexamethasone; Drug Synergism; Gastro | 2006 |
High-altitude retinopathy.
Topics: Adult; Altitude Sickness; Aspirin; Blood Cell Count; Fluorescein Angiography; Fundus Oculi; Hematocr | 1997 |
High-altitude headache.
Topics: Altitude Sickness; Aspirin; Headache; Humans | 1998 |
Spironolactone and acute mountain sickness.
Topics: Acute Disease; Adult; Altitude Sickness; Aspirin; Female; Furosemide; Humans; Hypoxia; Male; Middle | 1976 |
Transient ischemic attacks at high altitude.
Topics: Adult; Altitude Sickness; Aspirin; Fluid Therapy; Humans; Hypoxia; Ischemic Attack, Transient; Male; | 1986 |