aspirin has been researched along with Alloxan Diabetes in 91 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parenteral administration of gold thioglucose to mice produces an area or necrosis in the ventromedial portion of the hypothalamus." | 8.75 | Gold thioglucose obesity syndrome. ( Debons, AF; Fani, K; Jemenez, FA; Krimsky, I; Maayan, ML, 1977) |
| " The feasibility of controlling hyperglycemia in alloxan induced diabetic mice through hepatic synthesis of insulin was studied." | 7.78 | The control of hyperglycemia in alloxan treated diabetic mice through the stimulation of hepatic insulin synthesis due to the production of nitric oxide. ( Ghosh, R; Jana, P; Sinha, AK, 2012) |
| "To investigate the effect of carnosine (CA), aminoguanidine (AG), and aspirin (ASA) drops, all inhibitors of glycation, on the development of diabetic cataract in rat." | 7.74 | Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats. ( Ding, Z; Guo, Y; Ha, W; Harding, JJ; Yan, H; Zhang, J, 2008) |
| "The role of acetylation in the antiglycating and anticataract effects of aspirin (ASA) is explored by comparing ASA's effects with that of sodium salicylate (SS), a nonacetyl analog of ASA, on cataract development in diabetic rats." | 7.70 | Effect of aspirin and sodium salicylate on cataract development in diabetic rats. ( Kanagasabapathy, AS; Selvakumar, R; Shastri, GV; Thomas, K; Thomas, M; Victoria, AJ, 1998) |
| "Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract." | 7.68 | Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992) |
| "Type 1 diabetes mellitus was established by intraperitoneal injection of streptozotocin (65 mg/kg)." | 5.91 | Long-term aspirin administration suppresses inflammation in diabetic cystopathy. ( Du, H; Li, N; Liu, J; Qin, Y; Xu, F; Xu, Y; Zhang, J, 2023) |
| "Parenteral administration of gold thioglucose to mice produces an area or necrosis in the ventromedial portion of the hypothalamus." | 4.75 | Gold thioglucose obesity syndrome. ( Debons, AF; Fani, K; Jemenez, FA; Krimsky, I; Maayan, ML, 1977) |
| "Morphine is a drug used in chronic pain such as diabetic neuropathy, but the development of tolerance to its antinociceptive effect is an important clinical problem." | 4.31 | Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia. ( Avcı, O; Gunes, H; Gursoy, S; Inan, ZDS; Ozdemir, E; Taskiran, AS, 2023) |
| "It was concluded that simultaneous inhibition of the JAK-STAT and NF-κB signalling pathways with tofacitinib and aspirin respectively, could mitigate insulin resistance and hyperglycemia in T2D." | 3.91 | Inhibition of JAK-STAT and NF-κB signalling systems could be a novel therapeutic target against insulin resistance and type 2 diabetes. ( Bako, HY; Ibrahim, MA; Ibrahim, S; Isah, MS, 2019) |
| "Aspirin administration, reduced the protein expression of Mysm1, increased the protein expression of H2AK119-Ub and thereby reduced the Set7 protein expression in glomeruli isolated from diabetic animals and prevented renal fibrosis." | 3.88 | Novel reno-protective mechanism of Aspirin involves H2AK119 monoubiquitination and Set7 in preventing type 1 diabetic nephropathy. ( Gaikwad, AB; Goru, SK, 2018) |
| " The feasibility of controlling hyperglycemia in alloxan induced diabetic mice through hepatic synthesis of insulin was studied." | 3.78 | The control of hyperglycemia in alloxan treated diabetic mice through the stimulation of hepatic insulin synthesis due to the production of nitric oxide. ( Ghosh, R; Jana, P; Sinha, AK, 2012) |
| "Aspirin is a kind of anti-inflammatory drug and may be used to reverse hyperglycemia, hyperinsulinemia, and dyslipidemia by improving insulin resistance." | 3.77 | Effect of aspirin on the expression of hepatocyte NF-κB and serum TNF-α in streptozotocin-induced type 2 diabetic rats. ( Han, F; Han, L; Sun, X; Wang, B; Yi, J, 2011) |
| "It has been previously reported that aspirin inhibited the development of diabetic retinopathy in diabetic animals, raising the possibility that anti-inflammatory drugs may have beneficial effects on diabetic retinopathy." | 3.74 | Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. ( Hatala, DA; Howell, SJ; Huang, K; Kern, TS; Zheng, L, 2007) |
| "To investigate the effect of carnosine (CA), aminoguanidine (AG), and aspirin (ASA) drops, all inhibitors of glycation, on the development of diabetic cataract in rat." | 3.74 | Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats. ( Ding, Z; Guo, Y; Ha, W; Harding, JJ; Yan, H; Zhang, J, 2008) |
| " Diabetes was induced in Wistar male rats by single injection of streptozotocin, resulting after 8 weeks in significant body weight reduction, increased plasma glucose concentrations, and decreased plasma C-peptide levels, compared to non-diabetic animals." | 3.74 | French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. ( Durackova, Z; Muchova, J; Nocun, M; Ulicna, O; Watala, C, 2008) |
| "A nonselective inhibitor of cyclooxygenase (COX; high-dose aspirin) and a relatively selective inhibitor of inducible nitric oxide synthase (iNOS; aminoguanidine) have been found to inhibit development of diabetic retinopathy in animals, raising a possibility that NOS and COX play important roles in the development of retinopathy." | 3.72 | Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats. ( Du, Y; Kern, TS; Sarthy, VP, 2004) |
| "Gastric ulcers were induced in normal/NIDDM rats by various physical (2 hr cold restraint stress and 4 hr pylorus ligation) and chemical agents (ethanol, 1 ml/200 g, oral, 1 hr before; aspirin, 200 mg/kg, oral, 4 hr) and duodenal ulcers were induced by cysteamine (40 mg/200 g)." | 3.72 | Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. ( Agrawal, VK; Aryya, NC; Dorababu, M; Goel, RK; Prabha, T; Priyambada, S, 2004) |
| "The role of acetylation in the antiglycating and anticataract effects of aspirin (ASA) is explored by comparing ASA's effects with that of sodium salicylate (SS), a nonacetyl analog of ASA, on cataract development in diabetic rats." | 3.70 | Effect of aspirin and sodium salicylate on cataract development in diabetic rats. ( Kanagasabapathy, AS; Selvakumar, R; Shastri, GV; Thomas, K; Thomas, M; Victoria, AJ, 1998) |
| "Previous studies have demonstrated that urinary thromboxane B2 (TXB2) excretion (UTXB2) and glomerular production of TXB2 are enhanced in experimental diabetes and that selective inhibitors of TX synthesis prevent or delay the development of albuminuria." | 3.68 | Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat. ( Craven, PA; DeRubertis, FR, 1992) |
| "Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract." | 3.68 | Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992) |
| "The proliferation of aortic smooth muscle cells (ASMC) of Wistar rats, impaired by risk factors such as arterial hypertension, diabetes mellitus, atherogenic diet and staphylolysin injections and of normal Wistar rats treated with antirheumatic drugs such as prednisolone and acetylsalicylic acid was investigated." | 3.66 | Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells. ( Hauss, WH; Mey, J; Schulte, H, 1979) |
| "Type 1 diabetes mellitus was established by intraperitoneal injection of streptozotocin (65 mg/kg)." | 1.91 | Long-term aspirin administration suppresses inflammation in diabetic cystopathy. ( Du, H; Li, N; Liu, J; Qin, Y; Xu, F; Xu, Y; Zhang, J, 2023) |
| "Aspirin pretreatment of HP-diabetic animals is manifested with significantly lower blood and liver glucose, higher G6P concentration, lower G6P-ase and HK activity as well as higher Glk content and GPho-ase activity, compared both to diabetic and HP-diabetic animals." | 1.51 | Heat preconditioning and aspirin treatment attenuate hepatic carbohydrate-related disturbances in diabetic rats. ( Cipanovska, N; Dervisevic, M; Dimitrovska, M; Dinevska-Kjovkarovska, S; Miova, B, 2019) |
| "Aspirin has been reported to modulate heat shock response in different organisms through increased induction of HSPs and is also known to exert antioxidative and radical scavenging effects in diabetes." | 1.48 | Physiological and pharmacological inductors of HSP70 enhance the antioxidative defense mechanisms of the liver and pancreas in diabetic rats. ( Cipanovska, N; Dervisevik, M; Dimitrovska, M; Dinevska-Kjovkarovska, S; Gerazova, K; Miova, B, 2018) |
| "Aspirin treatment did not prevent the previously reported diabetes-induced marrow adiposity." | 1.37 | Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss. ( Coe, LM; Denison, JD; McCabe, LR, 2011) |
| "Inflammation is increasingly seen as the core process in the development of diabetes." | 1.36 | Combination of aspirin with telmisartan suppresses the augmented TGFbeta/smad signaling during the development of streptozotocin-induced type I diabetic nephropathy. ( Gaikwad, AB; Mulay, SR; Tikoo, K, 2010) |
| " In this study, we investigated the effect of high-dose and long-term use of acetyl salicylic acid (ASA) on the streptozotocin-induced diabetic rats as a model of type I diabetes, with consideration on the structure and/or function of proteins." | 1.35 | Investigation of the mechanisms involved in the high-dose and long-term acetyl salicylic acid therapy of type I diabetic rats. ( Bathaie, SZ; Hassan, MZ; Jafarnejad, A; Nakhjavani, M, 2008) |
| "Aspirin (30 mg/kg) treatment also reduced platelet aggregation." | 1.35 | Aspirin attenuates cerebral ischemic injury in diabetic rats. ( Fu, FH; Han, B; Wang, T; Yu, X; Zhang, LM; Zhu, M, 2009) |
| "The aim of this study was to assess the effect of chronic administration of NCX4016 [2 acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester], a nitric oxide-releasing aspirin derivative on the consequences of coronary artery occlusion in streptozotocin-diabetic rats." | 1.33 | The effect of NCX4016 [2-acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester] on the consequences of ischemia and reperfusion in the streptozotocin diabetic rat. ( Burke, SG; Furman, BL; Vojnovic, I; Wainwright, CL; Warner, T; Watson, DG, 2006) |
| "To explore its involvement in early diabetic nephropathy, we investigated the time course of CTGF gene expression and its regulation in streptozotocin (STZ)-induced diabetic rat kidney." | 1.32 | Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment. ( Fujinaga, Y; Makino, H; Mori, K; Mukoyama, M; Nakao, K; Suganami, T; Sugawara, A; Tanaka, I; Yahata, K; Yokoi, H, 2003) |
| "We compared the gastric toxic effect of aspirin (ASA) in both normal and diabetic rats, with that of NCX-4016, a derivative of ASA with nitric oxide (NO) releasing moiety." | 1.31 | Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats. ( Fujita, A; Takeuchi, K; Tashima, K; Umeda, M, 2000) |
| "Treatment with aspirin plus dipyridamole caused an inhibition of the platelet production of thromboxane B2 and a decrease in the vascular synthesis of prostacyclin." | 1.30 | Effect of aspirin plus dipyridamole on the retinal vascular pattern in experimental diabetes mellitus. ( De la Cruz, JP; García Campos, JM; Moreno, A; Muñoz, M; Sánchez de la Cuesta, F, 1997) |
| "Phentolamine pretreatment (5 mumol." | 1.28 | Increased vasoconstrictor response to noradrenaline in femoral vascular bed of diabetic dogs. Is thromboxane A2 involved? ( Ballagi-Pordány, G; Hadházy, P; Koltai, MZ; Pogátsa, G; Rösen, P, 1990) |
| "PDS from patients with NIDDM showed less PSA prior to the clinical onset of diabetic vascular complications, such as retinopathy and proteinuria." | 1.28 | Abnormality in prostacyclin-stimulatory activity in sera from diabetics. ( Inoguchi, T; Kunisaki, M; Nawata, H; Ono, H; Umeda, F; Watanabe, J, 1989) |
| " Met (1 X 10(-6) M) increased the tension of both normal and diabetic atria, but in diabetic atria, the dose-response curve to Met was shifted to the left and the efficacy of Met was enhanced." | 1.27 | Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats. ( Canga, L; Sterin-Borda, L, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (19.78) | 18.7374 |
| 1990's | 12 (13.19) | 18.2507 |
| 2000's | 25 (27.47) | 29.6817 |
| 2010's | 30 (32.97) | 24.3611 |
| 2020's | 6 (6.59) | 2.80 |
| Authors | Studies |
|---|---|
| Yelovitch, S | 1 |
| Barr, HM | 1 |
| Camden, J | 1 |
| Weisman, GA | 1 |
| Shai, E | 1 |
| Varon, D | 1 |
| Fischer, B | 1 |
| Xie, Y | 1 |
| Shao, L | 1 |
| Wang, Q | 1 |
| Bai, Y | 1 |
| Chen, Z | 1 |
| Li, N | 2 |
| Xu, Y | 2 |
| Li, Y | 1 |
| Yang, G | 1 |
| Bian, X | 1 |
| Dardenne, C | 1 |
| Salon, M | 1 |
| Authier, H | 1 |
| Meunier, E | 1 |
| AlaEddine, M | 1 |
| Bernad, J | 1 |
| Bouschbacher, M | 1 |
| Lefèvre, L | 1 |
| Pipy, B | 1 |
| Coste, A | 1 |
| Wu, Z | 4 |
| Li, D | 2 |
| Tian, D | 2 |
| Liu, X | 2 |
| Ozdemir, E | 1 |
| Avcı, O | 1 |
| Inan, ZDS | 1 |
| Taskiran, AS | 1 |
| Gunes, H | 1 |
| Gursoy, S | 1 |
| Du, H | 1 |
| Xu, F | 1 |
| Liu, J | 1 |
| Zhang, J | 3 |
| Qin, Y | 1 |
| Bako, HY | 1 |
| Ibrahim, MA | 1 |
| Isah, MS | 1 |
| Ibrahim, S | 1 |
| Nyambuya, TM | 1 |
| Dludla, PV | 1 |
| Nkambule, BB | 1 |
| Guo, X | 1 |
| Li, X | 1 |
| Yang, W | 1 |
| Liao, W | 1 |
| Shen, JZ | 1 |
| Ai, W | 1 |
| Pan, Q | 1 |
| Sun, Y | 1 |
| Zhang, K | 1 |
| Zhang, R | 1 |
| Qiu, Y | 1 |
| Dai, Q | 1 |
| Zheng, H | 1 |
| Guo, S | 1 |
| Şen, S | 1 |
| Çelik, S | 1 |
| Dimitrovska, M | 3 |
| Dervisevik, M | 2 |
| Cipanovska, N | 3 |
| Gerazova, K | 1 |
| Dinevska-Kjovkarovska, S | 2 |
| Miova, B | 3 |
| Goru, SK | 1 |
| Gaikwad, AB | 2 |
| Hao, WJ | 1 |
| Ke, SZ | 1 |
| Liu, L | 3 |
| Li, JH | 1 |
| Luo, XX | 1 |
| Sun, YF | 1 |
| Cao, J | 1 |
| Fan, L | 1 |
| Zhang, Y | 2 |
| Ma, KL | 2 |
| Gong, YX | 2 |
| Wang, GH | 2 |
| Hu, ZB | 2 |
| Lu, J | 2 |
| Chen, PP | 2 |
| Lu, CC | 2 |
| Ruan, XZ | 1 |
| Liu, BC | 2 |
| Gong, TK | 1 |
| Dervisevic, M | 1 |
| Paseban, M | 1 |
| Mohebbati, R | 1 |
| Niazmand, S | 1 |
| Sathyapalan, T | 1 |
| Sahebkar, A | 1 |
| Hafez, G | 1 |
| Gonulalan, U | 1 |
| Kosan, M | 1 |
| Arioglu, E | 1 |
| Ozturk, B | 1 |
| Cetinkaya, M | 1 |
| Gur, S | 1 |
| Bhatt, LK | 4 |
| Veeranjaneyulu, A | 3 |
| Yan, S | 1 |
| Zhang, Q | 1 |
| Zhong, X | 1 |
| Tang, J | 1 |
| Wang, Y | 1 |
| Yu, J | 1 |
| Zhou, Y | 1 |
| Guo, F | 1 |
| Liu, Y | 1 |
| FitzGerald, GA | 1 |
| Yu, Y | 1 |
| Dinevska-Kovkarovska, S | 1 |
| Korkmaz-Icöz, S | 1 |
| Al Said, S | 1 |
| Radovits, T | 1 |
| Li, S | 1 |
| Brune, M | 1 |
| Hegedűs, P | 1 |
| Atmanli, A | 1 |
| Ruppert, M | 1 |
| Brlecic, P | 1 |
| Lehmann, LH | 1 |
| Lahrmann, B | 1 |
| Grabe, N | 1 |
| Yoshikawa, Y | 1 |
| Yasui, H | 1 |
| Most, P | 1 |
| Karck, M | 1 |
| Szabó, G | 1 |
| Wang, T | 2 |
| Fu, FH | 2 |
| Han, B | 2 |
| Zhu, M | 1 |
| Yu, X | 1 |
| Zhang, LM | 2 |
| Yan, H | 1 |
| Guo, Y | 1 |
| Ding, Z | 1 |
| Ha, W | 1 |
| Harding, JJ | 2 |
| Jorge, AG | 1 |
| Módulo, CM | 1 |
| Dias, AC | 1 |
| Braz, AM | 1 |
| Filho, RB | 1 |
| Jordão, AA | 1 |
| de Paula, JS | 1 |
| Rocha, EM | 1 |
| Gerhardinger, C | 2 |
| Dagher, Z | 2 |
| Sebastiani, P | 1 |
| Park, YS | 1 |
| Lorenzi, M | 2 |
| Martha, S | 1 |
| Devarakonda, KR | 1 |
| Anreddy, RN | 1 |
| Pantam, N | 1 |
| De La Cruz, JP | 6 |
| Del Río, S | 2 |
| Arrebola, MM | 2 |
| López-Villodres, JA | 3 |
| Jebrouni, N | 3 |
| González-Correa, JA | 4 |
| Mulay, SR | 1 |
| Tikoo, K | 1 |
| Villalobos, MA | 1 |
| Zhang, XM | 1 |
| Yesilot, S | 1 |
| Ozer, MK | 1 |
| Bayram, D | 1 |
| Oncu, M | 1 |
| Karabacak, HI | 1 |
| Cicek, E | 1 |
| Sun, X | 1 |
| Han, F | 1 |
| Yi, J | 1 |
| Han, L | 1 |
| Wang, B | 1 |
| Addepalli, V | 1 |
| Coe, LM | 1 |
| Denison, JD | 1 |
| McCabe, LR | 1 |
| Ghosh, R | 1 |
| Jana, P | 1 |
| Sinha, AK | 1 |
| Muñoz-Marín, J | 1 |
| Guerrero, A | 3 |
| Yamada, K | 1 |
| Niki, H | 1 |
| Nagai, H | 1 |
| Nishikawa, M | 1 |
| Nakagawa, H | 1 |
| Pimple, BP | 1 |
| Kadam, PV | 1 |
| Patil, MJ | 1 |
| INGLE, DJ | 2 |
| MEEKS, RC | 1 |
| Makino, H | 2 |
| Mukoyama, M | 2 |
| Sugawara, A | 2 |
| Mori, K | 2 |
| Suganami, T | 2 |
| Yahata, K | 2 |
| Fujinaga, Y | 1 |
| Yokoi, H | 1 |
| Tanaka, I | 2 |
| Nakao, K | 2 |
| Dorababu, M | 1 |
| Prabha, T | 1 |
| Priyambada, S | 1 |
| Agrawal, VK | 1 |
| Aryya, NC | 1 |
| Goel, RK | 1 |
| Du, Y | 1 |
| Sarthy, VP | 1 |
| Kern, TS | 3 |
| Brzozowska, I | 1 |
| Targosz, A | 1 |
| Sliwowski, Z | 1 |
| Kwiecien, S | 1 |
| Drozdowicz, D | 1 |
| Pajdo, R | 1 |
| Konturek, PC | 1 |
| Brzozowski, T | 1 |
| Pawlik, M | 1 |
| Konturek, SJ | 1 |
| Pawlik, WW | 1 |
| Hahn, EG | 1 |
| Burke, SG | 1 |
| Wainwright, CL | 1 |
| Vojnovic, I | 1 |
| Warner, T | 1 |
| Watson, DG | 1 |
| Furman, BL | 1 |
| Sun, W | 1 |
| Hoehn, T | 1 |
| Ambrosini, MV | 1 |
| Mariucci, G | 1 |
| Rambotti, MG | 1 |
| Tantucci, M | 1 |
| Covarelli, C | 1 |
| De Angelis, L | 1 |
| Del Soldato, P | 2 |
| Xu, S | 1 |
| Jiang, B | 1 |
| Maitland, KA | 1 |
| Bayat, H | 1 |
| Gu, J | 1 |
| Nadler, JL | 1 |
| Corda, S | 1 |
| Lavielle, G | 1 |
| Verbeuren, TJ | 1 |
| Zuccollo, A | 1 |
| Cohen, RA | 1 |
| Watala, C | 3 |
| Ulicna, O | 2 |
| Golanski, J | 1 |
| Nocun, M | 3 |
| Waczulíková, I | 1 |
| Markuszewski, L | 1 |
| Drzewoski, J | 1 |
| Cañada, MJ | 1 |
| Muñoz Marín, J | 1 |
| Sánchez De la Cuesta, F | 4 |
| Lapshina, EA | 1 |
| Sudnikovich, EJ | 1 |
| Maksimchik, JZ | 1 |
| Zabrodskaya, SV | 1 |
| Zavodnik, LB | 1 |
| Kubyshin, VL | 1 |
| Kazmierczak, P | 1 |
| Dobaczewski, M | 1 |
| Zavodnik, IB | 1 |
| Zheng, L | 1 |
| Howell, SJ | 1 |
| Hatala, DA | 1 |
| Huang, K | 1 |
| Muchova, J | 1 |
| Durackova, Z | 1 |
| Jafarnejad, A | 1 |
| Bathaie, SZ | 1 |
| Nakhjavani, M | 1 |
| Hassan, MZ | 1 |
| Alonso, S | 1 |
| Ortega, MP | 1 |
| Armijo, M | 1 |
| Grünwald, J | 1 |
| Schäper, W | 1 |
| Mey, J | 2 |
| Hauss, WH | 2 |
| Peredo, H | 1 |
| Agostini, MD | 1 |
| Gimeno, MF | 1 |
| Borda, ES | 1 |
| Yue, DK | 2 |
| McLennan, S | 2 |
| Handelsman, DJ | 2 |
| Delbridge, L | 2 |
| Reeve, T | 2 |
| Turtle, JR | 2 |
| Colwell, JA | 1 |
| Halushka, PV | 1 |
| Sterin-Borda, L | 2 |
| Gimeno, M | 1 |
| Borda, E | 1 |
| del Castillo, E | 1 |
| Gimeno, AL | 1 |
| Courteix, C | 1 |
| Bardin, M | 1 |
| Chantelauze, C | 1 |
| Lavarenne, J | 1 |
| Eschalier, A | 1 |
| Jones, RH | 1 |
| Hothersall, JS | 1 |
| Franconi, F | 1 |
| Miceli, M | 1 |
| Fazzini, A | 1 |
| Seghieri, G | 1 |
| Caputo, S | 1 |
| DiLeo, MA | 1 |
| Lepore, D | 1 |
| Ghirlanda, G | 1 |
| Julu, PO | 1 |
| Gow, JW | 1 |
| Jamal, GA | 1 |
| Moreno, A | 3 |
| Muñoz, M | 1 |
| García Campos, JM | 1 |
| Shastri, GV | 1 |
| Thomas, M | 1 |
| Victoria, AJ | 1 |
| Selvakumar, R | 1 |
| Kanagasabapathy, AS | 1 |
| Thomas, K | 1 |
| Senoz, S | 1 |
| Kutukcu, Y | 1 |
| Aydin, A | 1 |
| Yildiz, O | 1 |
| Caballero, F | 1 |
| Gerez, E | 1 |
| Batlle, A | 1 |
| Vazquez, E | 1 |
| Tashima, K | 1 |
| Fujita, A | 1 |
| Umeda, M | 1 |
| Takeuchi, K | 1 |
| Engerman, RL | 1 |
| De La Cruz, P | 1 |
| Paniego, J | 1 |
| Arranz, I | 1 |
| Pieper, GM | 1 |
| Siebeneich, W | 1 |
| Olds, CL | 1 |
| Felix, CC | 1 |
| Muro, S | 1 |
| Ishibashi, R | 1 |
| Ohuchida, S | 1 |
| Maruyama, T | 1 |
| Narumiya, S | 1 |
| Macdonald, A | 1 |
| Dekanski, JB | 1 |
| Gottfried, S | 1 |
| Parke, DV | 1 |
| Sacra, P | 1 |
| Schulte, H | 1 |
| Debons, AF | 1 |
| Krimsky, I | 1 |
| Maayan, ML | 1 |
| Fani, K | 1 |
| Jemenez, FA | 1 |
| Koltai, MZ | 2 |
| Rösen, P | 2 |
| Hadházy, P | 2 |
| Aranyi, Z | 1 |
| Ballagi-Pordány, G | 2 |
| Pogátsa, G | 2 |
| DeRubertis, FR | 1 |
| Craven, PA | 1 |
| Blakytny, R | 1 |
| García Campos, J | 1 |
| Inoguchi, T | 1 |
| Umeda, F | 1 |
| Ono, H | 1 |
| Kunisaki, M | 1 |
| Watanabe, J | 1 |
| Nawata, H | 1 |
| Swamy, MS | 2 |
| Abraham, EC | 2 |
| Perry, RE | 1 |
| Canga, L | 1 |
| Moel, DI | 1 |
| Safirstein, RL | 1 |
| McEvoy, RC | 1 |
| Hsueh, W | 1 |
| Rendell, M | 1 |
| Nierenberg, J | 1 |
| Brannan, C | 1 |
| Valentine, JL | 1 |
| Stephen, PM | 1 |
| Dodds, S | 1 |
| Mercer, P | 1 |
| Smith, PK | 1 |
| Walder, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acetylsalicylic Acid Administered in Patients With Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System[NCT03341117] | Phase 3 | 21 participants (Actual) | Interventional | 2014-12-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aspirin and Alloxan Diabetes
| Article | Year |
|---|---|
Platelet function in diabetes mellitus.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Diabetes Mellitus; D | 1980 |
Gold thioglucose obesity syndrome.
Topics: Adrenalectomy; Animals; Appetite Regulation; Aspirin; Aurothioglucose; Biological Transport; Capilla | 1977 |
89 other studies available for aspirin and Alloxan Diabetes
| Article | Year |
|---|---|
Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist.
Topics: Animals; Blood Glucose; Cell Line, Tumor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2 | 2012 |
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Humans; | 2018 |
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Diabetes Mellitus, Experimental | 2022 |
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Topics: Animals; Aspirin; Cell Line; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathi | 2022 |
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Topics: Animals; Aspirin; Cell Line; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathi | 2022 |
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Topics: Animals; Aspirin; Cell Line; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathi | 2022 |
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition.
Topics: Animals; Aspirin; Cell Line; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathi | 2022 |
Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia.
Topics: Analgesics; Animals; Apoptosis; Aspirin; bcl-2-Associated X Protein; Caspase 3; Diabetes Mellitus, E | 2023 |
Long-term aspirin administration suppresses inflammation in diabetic cystopathy.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Inflammation; Male; Ra | 2023 |
Inhibition of JAK-STAT and NF-κB signalling systems could be a novel therapeutic target against insulin resistance and type 2 diabetes.
Topics: Animals; Aspirin; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type | 2019 |
The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Aspirin; Blood Glucose; Diabetes Mel | 2021 |
Metformin Targets Foxo1 to Control Glucose Homeostasis.
Topics: Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; | 2021 |
The effect of acetylsalicylic acid on vasopressin, serum insulin levels, insulin resistance, and biochemical parameters in rats induced with experimental diabetes type 2.
Topics: Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin | 2017 |
Physiological and pharmacological inductors of HSP70 enhance the antioxidative defense mechanisms of the liver and pancreas in diabetic rats.
Topics: Animals; Antioxidants; Aspirin; Body Temperature; Diabetes Mellitus, Experimental; Heat-Shock Respon | 2018 |
Novel reno-protective mechanism of Aspirin involves H2AK119 monoubiquitination and Set7 in preventing type 1 diabetic nephropathy.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies | 2018 |
[The experimental study of simvastatin on improving aspirin resistance in diabetic rats].
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Epoprostenol; Male; Nitric | 2016 |
Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy.
Topics: Animals; Aspirin; Blood Platelets; Cell-Derived Microparticles; Cells, Cultured; Chemokines, CXC; Di | 2018 |
Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway.
Topics: Albuminuria; Animals; Aspirin; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; | 2019 |
Heat preconditioning and aspirin treatment attenuate hepatic carbohydrate-related disturbances in diabetic rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Glucose; Glycogen; Heat-Shock Response; Hyperther | 2019 |
Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus.
Topics: Animals; Aspirin; Atorvastatin; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Mal | 2019 |
Acetylsalicylic acid protects erectile function in diabetic rats.
Topics: Acetylcholine; Animals; Aspirin; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Experime | 2014 |
Enhancement of matrix metalloproteinase 2 and 9 inhibitory action of minocycline by aspirin: an approach to attenuate outcome of acute myocardial infarction in diabetes.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Drug Synergism; Hemodynamics; Male; Matrix Metall | 2014 |
I prostanoid receptor-mediated inflammatory pathway promotes hepatic gluconeogenesis through activation of PKA and inhibition of AKT.
Topics: Animals; Aspirin; Cell Cycle Proteins; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Expe | 2014 |
High dose of aspirin moderates diabetes-induced changes of heart glycogen/glucose metabolism in rats.
Topics: Animals; Aspirin; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; G | 2014 |
Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway.
Topics: Administration, Oral; Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; | 2016 |
Aspirin attenuates cerebral ischemic injury in diabetic rats.
Topics: Animals; Aspirin; Blood Glucose; Brain Ischemia; Cerebral Infarction; Diabetes Mellitus, Experimenta | 2009 |
Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; Carnosine; Cataract; Cornea; Diabetes Mellitus, Experi | 2008 |
Aspirin prevents diabetic oxidative changes in rat lacrimal gland structure and function.
Topics: Animals; Aspirin; Cell Nucleus; Diabetes Mellitus, Experimental; Ion Channels; Lacrimal Apparatus; M | 2009 |
The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression Profiling; | 2009 |
Effect of aspirin treatment in streptozotocin-induced type 2 diabetic rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; I-kappa B Kina | 2009 |
Effect of virgin olive oil plus acetylsalicylic acid on brain slices damage after hypoxia-reoxygenation in rats with type 1-like diabetes mellitus.
Topics: Animals; Aspirin; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoxia, Brain; | 2010 |
Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Neuropathies; | 2010 |
Combination of aspirin with telmisartan suppresses the augmented TGFbeta/smad signaling during the development of streptozotocin-induced type I diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2010 |
Virgin olive oil administration improves the effect of aspirin on retinal vascular pattern in experimental diabetes mellitus.
Topics: Animals; Aorta; Aspirin; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Horseradish Per | 2010 |
Long-term but not short-term aspirin treatment attenuates diabetes-associated learning and memory decline in mice.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2011 |
Effects of aspirin and nimesulide on tissue damage in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Diabetes Mellitus, Experimental | 2010 |
A therapeutic approach to treat cardiovascular dysfunction of diabetes.
Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Cardiomyo | 2012 |
Effect of aspirin on the expression of hepatocyte NF-κB and serum TNF-α in streptozotocin-induced type 2 diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Diabetes Mellitus, Experim | 2011 |
Potentiation of aspirin-induced cerebroprotection by minocycline: a therapeutic approach to attenuate exacerbation of transient focal cerebral ischaemia.
Topics: Animals; Aspirin; Blood Glucose; Blood-Brain Barrier; Body Weight; Brain; Brain Edema; Capillary Per | 2012 |
Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss.
Topics: Adiposity; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Bone and Bones; | 2011 |
The control of hyperglycemia in alloxan treated diabetic mice through the stimulation of hepatic insulin synthesis due to the production of nitric oxide.
Topics: Administration, Cutaneous; Administration, Oral; Alloxan; Animals; Anti-Inflammatory Agents, Non-Ste | 2012 |
Effects of terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, on retinal vascularity in diabetic rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Epoprostenol; Lipid Peroxid | 2012 |
Serotonin potentiates high-glucose-induced endothelial injury: the role of serotonin and 5-HT(2A) receptors in promoting thrombosis in diabetes.
Topics: Animals; Aspirin; Cells, Cultured; Cilostazol; Diabetes Mellitus, Experimental; Fibrinolytic Agents; | 2012 |
Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants.
Topics: Animals; Antioxidants; Aspirin; Biomarkers; Catalase; Diabetes Mellitus, Experimental; Dose-Response | 2012 |
Suppression of glycosuria during administration of large doses of aspirin to force-fed partially depancreatectomized rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Glycosuria; Rats | 1952 |
Effects of aspirin, aminopyrine, and HPC upon glycosuria in the diabetic rat.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Diabetes Mellitus, Experimental; Glycosuria; Quinolines; | 1953 |
Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment.
Topics: Animals; Aspirin; Blotting, Northern; Cells, Cultured; Connective Tissue Growth Factor; Cyclooxygena | 2003 |
Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Aspirin; Azadirachta; Bacopa; Cold Temperature; Diabetes Me | 2004 |
Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats.
Topics: Animals; Aspirin; Blotting, Western; Cattle; Cell Death; Cells, Cultured; Cyclooxygenase 2; Diabetes | 2004 |
Healing of chronic gastric ulcers in diabetic rats treated with native aspirin, nitric oxide (NO)-derivative of aspirin and cyclooxygenase (COX)-2 inhibitor.
Topics: Animals; Aspirin; Chronic Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inh | 2004 |
The effect of NCX4016 [2-acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester] on the consequences of ischemia and reperfusion in the streptozotocin diabetic rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Calcimycin; Diabetes Mell | 2006 |
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; | 2005 |
Ultrastructural investigations on protective effects of NCX 4016 (nitroaspirin) on macrovascular endothelium in diabetic Wistar rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Diabetes Mellitus, Experimental; E | 2005 |
The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice.
Topics: Animals; Apolipoproteins E; Arachidonate 12-Lipoxygenase; Aspirin; Diabetes Mellitus, Experimental; | 2006 |
High glucose contributes to aspirin insensitivity in streptozotocin-diabetic rats: a multiparametric aggregation study.
Topics: Animals; Aspirin; Blood Glucose; Blood Platelets; Chronic Disease; Diabetes Mellitus, Experimental; | 2006 |
Antioxidant and antiplatelet effects of the alpha-tocopherol-aspirin combination in type 1-like diabetic rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2006 |
Antioxidative enzyme and glutathione S-transferase activities in diabetic rats exposed to long-term ASA treatment.
Topics: Animals; Antioxidants; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angiopathie | 2006 |
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Diabete | 2007 |
French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; C-Peptide; Cyclooxygenase Inhibitors; Diabetes Mellitu | 2008 |
Investigation of the mechanisms involved in the high-dose and long-term acetyl salicylic acid therapy of type I diabetic rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Ty | 2008 |
[Activity of eterilate, benorylate and acetylsalicylic acid on blood glucose in normal and experimentally diabetic rats].
Topics: Acetanilides; Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Female; Hypoglycemia | 1983 |
Special characteristics of cultured smooth muscle cell subtypes of hypertensive and diabetic rats.
Topics: Animals; Aorta; Aspirin; Cell Line; Diabetes Mellitus, Experimental; Hypertension, Renal; Male; Musc | 1982 |
Hypersensitivity to norepinephrine in vasa deferentia from diabetic rats. Possible participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Catechols; Diabetes Mel | 1984 |
The effect of salicylates on nonenzymatic glycosylation and thermal stability of collagen in diabetic rats.
Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; E | 1984 |
Prostacyclin (PGI2) and U-46619 stimulate coronary arteries from diabetic dogs and their action is influenced by inhibitors of prostaglandin biosynthesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agent | 1981 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experi | 1994 |
Increased susceptibility to metal catalysed oxidation of diabetic lens beta L crystallin: possible protection by dietary supplementation with acetylsalicylic acid.
Topics: Animals; Ascorbic Acid; Aspirin; Cataract; Copper; Crystallins; Diabetes Mellitus, Experimental; Hyd | 1993 |
Taurine and diabetes. Humans and experimental models.
Topics: Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diabetes Mellitus, Experimental; Diabetes Melli | 1996 |
Endogenous cyclo-oxygenase substrates mediate the neuroactivity of evening primrose oil in rats.
Topics: Animals; Aspirin; Blood Glucose; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabeti | 1996 |
Effect of aspirin plus dipyridamole on the retinal vascular pattern in experimental diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Diabetes Mellitus, Experimental; Dipyridamole; Epopr | 1997 |
Effect of aspirin and sodium salicylate on cataract development in diabetic rats.
Topics: Animals; Aspirin; Cataract; Diabetes Mellitus, Experimental; Disease Progression; Drug Evaluation, P | 1998 |
Acetyl salicylic acid improves somatosensory evoked potentials in streptozotocin-diabetic rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Evoked Potentials, Somatosensory; Male; Rats; Rat | 1999 |
Preventive aspirin treatment of streptozotocin induced diabetes: blockage of oxidative status and revertion of heme enzymes inhibition.
Topics: Animals; Aspirin; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Diet; Eating; Enzyme Inh | 2000 |
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa; | 2000 |
Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Blood Glucose; Diabet | 2001 |
Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathy.
Topics: Administration, Oral; Animals; Aorta; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy | 2002 |
Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Diabetes | 2002 |
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist.
Topics: Animals; Aspirin; Autocrine Communication; Cells, Cultured; Cinnamates; Cyclooxygenase Inhibitors; D | 2002 |
Effects of blood glucose levels on aspirin-induced gastric mucosal damage.
Topics: Adrenal Cortex Hormones; Animals; Aspirin; Blood Glucose; Bucladesine; Cyclic AMP; Cyclic GMP; Diabe | 1977 |
Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells.
Topics: Animals; Aorta; Arteriosclerosis; Aspirin; Cell Division; Cells, Cultured; Chloroquine; Diabetes Mel | 1979 |
Disturbed lipid metabolism in diabetic coronary vessels.
Topics: Alloxan; Animals; Arachidonic Acids; Aspirin; Coronary Circulation; Coronary Vessels; Diabetes Melli | 1992 |
Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat.
Topics: Albuminuria; Animals; Aspirin; Blood Platelets; Diabetes Mellitus, Experimental; Dinoprostone; Femal | 1992 |
Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen.
Topics: Acetaminophen; Animals; Aspirin; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Female; G | 1992 |
Effect of antiplatelet drug therapy on the retinal vascular pattern in experimental diabetes mellitus.
Topics: Animals; Aspirin; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dipyridamole; Dr | 1990 |
Increased vasoconstrictor response to noradrenaline in femoral vascular bed of diabetic dogs. Is thromboxane A2 involved?
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Re | 1990 |
Abnormality in prostacyclin-stimulatory activity in sera from diabetics.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cells, C | 1989 |
Inhibition of lens crystallin glycation and high molecular weight aggregate formation by aspirin in vitro and in vivo.
Topics: Animals; Aspirin; Cataract; Crystallins; Diabetes Mellitus, Experimental; Glucose; In Vitro Techniqu | 1989 |
Nonenzymatic glycosylation (glycation) of lens crystallins in diabetes and aging.
Topics: Acetylation; Aging; Animals; Aspirin; Cataract; Crystallins; Diabetes Mellitus, Experimental; Glycos | 1989 |
Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experi | 1986 |
Effect of aspirin on experimental diabetic nephropathy.
Topics: Animals; Aspirin; Basement Membrane; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Di | 1987 |
Inhibition of glycation of albumin and hemoglobin by acetylation in vitro and in vivo.
Topics: Acetylation; Animals; Aspirin; Blood Glucose; Borohydrides; Diabetes Mellitus, Experimental; Glycosy | 1986 |
The effects of cyclooxygenase and lipoxygenase inhibitors on the collagen abnormalities of diabetic rats.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhib | 1985 |