aspirin has been researched along with Allergic Encephalomyelitis in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin has the potential to ameliorate the disease process in multiple sclerosis (for example, by limiting some components of inflammation), but aspirin also has the potential to inhibit mitochondrial complex I activity, which is already reduced in multiple sclerosis." | 6.52 | Aspirin and multiple sclerosis. ( Emerson, MR; LeVine, SM; Lynch, SG; Tsau, S, 2015) |
| "Aspirin treatment led to an increased PGF production by brain slices from rats on either diet and not subjected to an immunochallenge." | 5.26 | Incidence and severity of experimental allergic encephalomyelitis and cerebral prostaglandin synthesis in essential fatty acid deficient and aspirin-treated rats. ( Johnston, PV; Weston, PG, 1978) |
| "Aspirin has the potential to ameliorate the disease process in multiple sclerosis (for example, by limiting some components of inflammation), but aspirin also has the potential to inhibit mitochondrial complex I activity, which is already reduced in multiple sclerosis." | 2.52 | Aspirin and multiple sclerosis. ( Emerson, MR; LeVine, SM; Lynch, SG; Tsau, S, 2015) |
| "Aspirin treatment led to an increased PGF production by brain slices from rats on either diet and not subjected to an immunochallenge." | 1.26 | Incidence and severity of experimental allergic encephalomyelitis and cerebral prostaglandin synthesis in essential fatty acid deficient and aspirin-treated rats. ( Johnston, PV; Weston, PG, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vogelsang, A | 1 |
| Eichler, S | 1 |
| Huntemann, N | 1 |
| Masanneck, L | 1 |
| Böhnlein, H | 1 |
| Schüngel, L | 1 |
| Willison, A | 1 |
| Loser, K | 1 |
| Nieswandt, B | 1 |
| Kehrel, BE | 1 |
| Zarbock, A | 1 |
| Göbel, K | 1 |
| Meuth, SG | 1 |
| Mondal, S | 1 |
| Jana, M | 1 |
| Dasarathi, S | 1 |
| Roy, A | 1 |
| Pahan, K | 2 |
| Pahan, S | 1 |
| Yang, X | 1 |
| Jing, H | 1 |
| Zhao, K | 1 |
| Sun, R | 1 |
| Liu, Z | 1 |
| Ying, Y | 1 |
| Ci, L | 1 |
| Kuang, Y | 1 |
| Huang, F | 1 |
| Wang, Z | 1 |
| Fei, J | 1 |
| Tsau, S | 1 |
| Emerson, MR | 1 |
| Lynch, SG | 1 |
| LeVine, SM | 1 |
| Rosenthale, ME | 2 |
| Nagra, CL | 1 |
| Weston, PG | 1 |
| Johnston, PV | 1 |
| Begany, AJ | 1 |
| Dervinis, A | 1 |
| Malis, JL | 1 |
| Shriver, DA | 1 |
| Datko, SL | 1 |
| Gluckman, MI | 1 |
2 reviews available for aspirin and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Mode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclic AMP Response Element-Binding Prote | 2019 |
Aspirin and multiple sclerosis.
Topics: Animals; Aspirin; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Platelet | 2015 |
6 other studies available for aspirin and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Platelet Inhibition by Low-Dose Acetylsalicylic Acid Reduces Neuroinflammation in an Animal Model of Multiple Sclerosis.
Topics: Animals; Aspirin; Blood Platelets; Brain; CD4-Positive T-Lymphocytes; Disease Models, Animal; Dose-R | 2021 |
Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cyclic AMP Response Elem | 2018 |
Functional imaging of Rel expression in inflammatory processes using bioluminescence imaging system in transgenic mice.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Encephalomyelitis, Autoimmune, Experiment | 2013 |
Comparative effects of some immunosuppressive and anti-inflammotory drugs on allergic encephalomyelitis and adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Cell Count; Body Weight; Cortisone; Enc | 1967 |
Incidence and severity of experimental allergic encephalomyelitis and cerebral prostaglandin synthesis in essential fatty acid deficient and aspirin-treated rats.
Topics: Animals; Aspirin; Brain; Brain Chemistry; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, | 1978 |
Anti-inflammatory properties of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin).
Topics: Airway Obstruction; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; B | 1974 |