Page last updated: 2024-10-22

aspirin and Alcohol Drinking

aspirin has been researched along with Alcohol Drinking in 131 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"The Aspirin/Folate Polyp Prevention Study is a randomized clinical trial of folic acid supplementation and incidence of new colorectal adenomas in individuals with a history of adenomas (n = 1,084)."9.13Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation. ( Ahnen, DJ; Ali, I; Baron, JA; Barry, EL; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; Midttun, O; Munroe, D; Sandler, RS; Tsang, S; Ueland, PM, 2008)
"We performed multivariate logistic regression analysis of 2012 participants given aspirin alone or in combination with low, inefficacious doses of warfarin in the Stroke Prevention in Atrial Fibrillation I-III trials followed for a mean of 2."9.09Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation: analysis of 2012 participants in the SPAF I-III clinical trials. The Stroke Prevention in Atrial Fibrillation (SPAF) Investigators. ( Asinger, RW; Hart, RG; McBride, R; Pearce, LA; Rothbart, RM, 1999)
"Seventy-two patients with endoscopically proven gastric ulcers were entered into a prospective controlled trial to assess the efficacy of ranitidine and cimetidine in ulcer healing."9.05Ranitidine in the treatment of gastric ulceration. ( Bornman, PC; Gilinsky, NH; Girdwood, AH; Lucke, W; Marks, IN; Mee, AS; Tobias, P; Wright, JP, 1982)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."7.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
"311 subjects with single/multiple colorectal adenomas and adenocarcinomas excised by endoscopy were enrolled in the study (152 patients in the aspirin group and 159 patients in the placebo group)."5.19The preventive effects of low-dose enteric-coated aspirin tablets on the development of colorectal tumours in Asian patients: a randomised trial. ( Abe, T; Gondo, N; Goto, C; Iimuro, M; Ishikawa, H; Joh, T; Kitamura, S; Kudo, SE; Kusunoki, M; Lee, K; Matsuda, T; Matsuura, N; Mizuno, M; Mutoh, M; Okamura, S; Saida, Y; Sakai, T; Sano, Y; Sato, Y; Sugimoto, K; Suzuki, S; Tajika, M; Takayama, T; Tanaka, S; Tokudome, S; Wakabayashi, K; Yukawa, T, 2014)
"Our data were collected as part of a randomized clinical trial testing the efficacy of aspirin and folic acid for the prevention of colorectal adenomas."5.14Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. ( Baron, JA; Bresalier, RS; Chen, X; Figueiredo, JC; Grau, MV; Haile, RW; Hamdan, R; Issa, JP; Levine, AJ; McKeown-Eyssen, G; Shen, L; Wallace, K, 2009)
"The Aspirin/Folate Polyp Prevention Study is a randomized clinical trial of folic acid supplementation and incidence of new colorectal adenomas in individuals with a history of adenomas (n = 1,084)."5.13Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation. ( Ahnen, DJ; Ali, I; Baron, JA; Barry, EL; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; Midttun, O; Munroe, D; Sandler, RS; Tsang, S; Ueland, PM, 2008)
"We performed multivariate logistic regression analysis of 2012 participants given aspirin alone or in combination with low, inefficacious doses of warfarin in the Stroke Prevention in Atrial Fibrillation I-III trials followed for a mean of 2."5.09Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation: analysis of 2012 participants in the SPAF I-III clinical trials. The Stroke Prevention in Atrial Fibrillation (SPAF) Investigators. ( Asinger, RW; Hart, RG; McBride, R; Pearce, LA; Rothbart, RM, 1999)
"0001) after adjustment for age, aspirin use, smoking, physical activity, body mass index, and history of angina, hypertension, and high cholesterol."5.09Alcohol consumption and risk of coronary heart disease by diabetes status. ( Ajani, UA; Buring, JE; Gaziano, JM; Hennekens, CH; Liu, S; Lotufo, PA; Manson, JE, 2000)
"Seventy-two patients with endoscopically proven gastric ulcers were entered into a prospective controlled trial to assess the efficacy of ranitidine and cimetidine in ulcer healing."5.05Ranitidine in the treatment of gastric ulceration. ( Bornman, PC; Gilinsky, NH; Girdwood, AH; Lucke, W; Marks, IN; Mee, AS; Tobias, P; Wright, JP, 1982)
"2%) was positively associated with age, male gender, smoking and alcohol drinking, and inversely associated with physical activity, fruit and vegetables consumption and long-term use of aspirin."3.83Predictors of advanced colorectal neoplasia at initial and surveillance colonoscopy after positive screening immunochemical faecal occult blood test. ( Bagnardi, V; Botteri, E; Crosta, C; de Leone, A; De Roberto, G; Lowenfels, A; Maisonneuve, P; Sonzogni, AM; Tamayo, D, 2016)
" Male gender, smoking, alcohol drinking, consumption of coffee, large waist circumference, infrequent medication of antacids, aspirin and NSAIDs, infrequent and mild GERD symptoms were all significantly associated with ED on univariate analysis."3.77[Clinical characteristics of gastroesophageal reflux disease with esophageal injury in korean: focusing on risk factors]. ( Cho, KB; Jang, BI; Jeon, SW; Jung, JT; Jung, MK; Kim, ES; Kim, EY; Kim, KO; Kim, SK; Kwon, JG; Lee, JH; Lee, SH; Lee, SJ; Park, CK; Park, KS; Seo, HE; Yang, CH, 2011)
" The Task Force has: 1) dropped the age for routine screening for Chlamydia in sexually active women from 25 years and younger to 24 and younger; 2) added a recommendation against the use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent colorectal cancer (CRC); 3) changed its recommendation on screening for carotid artery stenosis."3.74Should you screen--or not? The latest recommendations. ( Campos-Outcalt, D, 2008)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."3.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
"Clinical and endoscopic findings as well as Helicobacter pylori status, gastric secretion analysis, serum gastrin levels, nonsteroidal anti-inflammatory drug (NSAID) use, and objective testing of aspirin use by platelet cyclooxygenase activity were studied in 60 consecutive refractory patients with peptic ulcer and 54 matched nonrefractory controls."3.69Risk factors associated with refractory peptic ulcers. ( Esteva, F; Lanas, AI; Remacha, B; Sáinz, R, 1995)
"Smoking, alcohol, aspirin, non-aspirin NSAIDs, and acetaminophen were not associated with functional dyspepsia."3.69Smoking, alcohol, and nonsteroidal anti-inflammatory drugs in outpatients with functional dyspepsia and among dyspepsia subgroups. ( Talley, NJ; Weaver, AL; Zinsmeister, AR, 1994)
"We examined in a controlled study whether psychologic disturbances in men with peptic ulcer disease were related to other potential ulcer "risk factors" (serum pepsinogen concentrations, cigarette smoking, and intake of alcohol, aspirin, or coffee)."3.67Life events stress and psychosocial factors in men with peptic ulcer disease. II. Relationships with serum pepsinogen concentrations and behavioral risk factors. ( Feldman, M; Luther, J; Samloff, IM; Walker, P, 1988)
"Although pharmacologic treatment for hyperlipidemia had the greatest favorable impact on the ratio over time, our data also show that maintaining an ideal weight and exercise have beneficial effects."2.71Predictors of 14-year changes in the total cholesterol to high-density lipoprotein cholesterol ratio in men. ( Buring, JE; Gaziano, JM; Levenson, JW; Scranton, R; Sesso, HD; Stampfer, MJ, 2004)
" Opioids should not be combined with alcohol, and meperidine must be avoided in the patient who has taken monoamine oxidase inhibitors in the previous 14 days."2.40Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series. ( Haas, DA, 1999)
"Dyspepsia is prevalent in the Rwandan setting and is associated with a significant burden on quality of life."1.56Prevalence and sociodemographic determinants of dyspepsia in the general population of Rwanda. ( Bangamwabo, JB; Chetwood, JD; Dusabejambo, V; Jones, M; Kieffer, KA; Nkurunziza, A; Ntirenganya, C; Nuki, G; Walker, TD, 2020)
"Risk models for advanced colorectal neoplasms generally yielded modest discriminatory power, despite some variation in performance between models."1.51Head-to-Head Comparison of the Performance of 17 Risk Models for Predicting Presence of Advanced Neoplasms in Colorectal Cancer Screening. ( Balavarca, Y; Brenner, H; Hoffmeister, M; Peng, L; Weigl, K, 2019)
"Endoscopic features of eosinophilic esophagitis (EoE) are variable with at least 2 phenotypes."1.43Impact of Diagnostic Delay and Other Risk Factors on Eosinophilic Esophagitis Phenotype and Esophageal Diameter. ( Kumar, A; Lipka, S; Richter, JE, 2016)
"We described the cardioembolic (Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack [CHADS2]/Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack, Vascular disease, Age 65-75, Sex category i."1.40Stroke and bleeding risk co-distribution in real-world patients with atrial fibrillation: the Euro Heart Survey. ( Crijns, HJ; Iorio, A; Lip, GY; Marcucci, M; Nieuwlaat, R; Pisters, R, 2014)
"Previously, all reports of intracranial hemorrhages in MDMA abusers were associated with coingestion of other sympathomimetic drugs, or with pre-existing cerebrovascular lesions."1.383 cases of primary intracranial hemorrhage associated with "Molly", a purified form of 3,4-methylenedioxymethamphetamine (MDMA). ( Benveniste, RJ; Ferraro, N; Kahn, DE, 2012)
"Ibuprofen based drugs were the most frequently used OTC in both surveys (57% Roper, 33% NCL)."1.33Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs. ( Cryer, B; Triadafilopoulos, G; Wilcox, CM, 2005)
"Complications of Zenker's diverticulum are rare and include ulcer, bleeding and malignancy."1.33Ulcer in the basis of Zenker's diverticulum mimicking esophageal malignancy. ( Ataseven, H; Basar, O; Ertugrul, I; Odemis, B; Turhan, N; Yüksel, O, 2006)
"Aspirin use was associated with a 25% reduction in the risk of head and neck cancer (adjusted odds ratio, 0."1.33Chemoprevention of head and neck cancer with aspirin: a case-control study. ( Jayaprakash, V; Loree, TR; Menezes, RJ; Moysich, KB; Nasca, MA; Reid, ME; Rigual, NR, 2006)
"A case-control study of stomach cancer which includes 448 cases and 610 hospital controls has been conducted in Moscow, Russia."1.30Aspirin protects against gastric cancer: results of a case-control study from Moscow, Russia. ( Borisova, E; Chkhikvadze, V; Maximovitch, D; Zaridze, D, 1999)
"Dyspepsia was significantly more common in younger subjects and females."1.29Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups: lack of an association in a community. ( Melton, LJ; Schleck, CD; Talley, NJ; Zinsmeister, AR, 1994)
" There was a linear dose-response curve that was steeper in women than in men."1.29Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. ( Dobson, A; Henry, D; Turner, C, 1993)
" Thus, aspirin may increase the bioavailability of ingested ethanol in humans, possibly by reducing ethanol oxidation by gastric alcohol dehydrogenase."1.28Aspirin increases blood alcohol concentrations in humans after ingestion of ethanol. ( Baraona, E; Gentry, RT; Hernández-Munõz, R; Lieber, CS; Roine, R, 1990)

Research

Studies (131)

TimeframeStudies, this research(%)All Research%
pre-199029 (22.14)18.7374
1990's41 (31.30)18.2507
2000's29 (22.14)29.6817
2010's25 (19.08)24.3611
2020's7 (5.34)2.80

Authors

AuthorsStudies
Ezquer, F2
Quintanilla, ME2
Morales, P2
Santapau, D2
Munita, JM1
Moya-Flores, F1
Ezquer, M2
Herrera-Marschitz, M2
Israel, Y2
Peng, L1
Balavarca, Y1
Weigl, K1
Hoffmeister, M1
Brenner, H1
Berríos-Cárcamo, P1
Olivares, B1
Bangamwabo, JB1
Chetwood, JD1
Dusabejambo, V1
Ntirenganya, C1
Nuki, G1
Nkurunziza, A1
Kieffer, KA1
Jones, M1
Walker, TD1
Chapelle, N1
Martel, M1
Toes-Zoutendijk, E1
Barkun, AN1
Bardou, M1
Simon, TG1
Chan, AT2
Liebow, M1
Larson, MC1
Thompson, CA1
Nowakowski, GS1
Call, TG1
Macon, WR1
Kay, NE1
Habermann, TM1
Slager, SL1
Cerhan, JR1
Zhao, Z1
Yin, Z1
Zhang, C1
Qiu, J1
Grine, K1
Glicksman, JT1
Parasher, AK1
Doghramji, L1
Brauer, D1
Waldram, J1
Walters, K1
Bulva, J1
Palmer, JN1
Adappa, ND1
White, AA1
Bosso, JV1
Wilson, N1
Jones, AC1
Nghiem, N1
Blakely, T1
Wilson, JC2
Murray, LJ1
Hughes, CM2
Black, A1
Anderson, LA1
Jiang, Z1
Wu, H1
Duan, Z1
Wang, Z1
Hu, K1
Ye, F1
Zhang, Z1
Ishikawa, H1
Mutoh, M1
Suzuki, S1
Tokudome, S1
Saida, Y1
Abe, T1
Okamura, S1
Tajika, M1
Joh, T1
Tanaka, S3
Kudo, SE1
Matsuda, T1
Iimuro, M1
Yukawa, T1
Takayama, T1
Sato, Y1
Lee, K1
Kitamura, S1
Mizuno, M1
Sano, Y1
Gondo, N1
Sugimoto, K1
Kusunoki, M1
Goto, C1
Matsuura, N1
Sakai, T1
Wakabayashi, K1
Nagata, N2
Niikura, R2
Aoki, T2
Shimbo, T2
Kishida, Y2
Sekine, K2
Watanabe, K2
Sakurai, T2
Yokoi, C2
Akiyama, J2
Yanase, M2
Mizokami, M2
Uemura, N2
Marcucci, M1
Lip, GY1
Nieuwlaat, R1
Pisters, R1
Crijns, HJ1
Iorio, A1
Okubo, H1
Lipka, S1
Kumar, A1
Richter, JE1
Argulian, E1
Conen, D1
Messerli, FH1
Becker, C1
Jick, SS1
Meier, CR1
Botteri, E1
Crosta, C1
Bagnardi, V1
Tamayo, D1
Sonzogni, AM1
De Roberto, G1
de Leone, A1
Lowenfels, A1
Maisonneuve, P1
Begovic, G1
Selmani, R1
Strate, LL1
Singh, P1
Boylan, MR1
Piawah, S1
Cao, Y1
Campos-Outcalt, D1
Figueiredo, JC2
Levine, AJ2
Grau, MV3
Midttun, O1
Ueland, PM2
Ahnen, DJ1
Barry, EL2
Tsang, S1
Munroe, D1
Ali, I1
Haile, RW3
Sandler, RS1
Baron, JA4
Myint, PK1
Luben, RN1
Wareham, NJ1
Bingham, SA1
Khaw, KT1
Wallace, K2
Shen, L1
Hamdan, R1
Chen, X1
Bresalier, RS1
McKeown-Eyssen, G2
Issa, JP1
Ahnen, D1
Snover, DC1
Robertson, DJ1
Mahnke, D1
Gui, J1
Summers, RW1
Rist, PM1
Berger, K2
Buring, JE5
Kase, CS2
Gaziano, JM5
Kurth, T2
Hazra, A1
Selhub, J2
Chao, WH1
Hunter, DJ2
Hatoum, IJ1
Nelson, JJ1
Cook, NR1
Hu, FB1
Rimm, EB2
Lee, SW1
Chang, CS1
Lee, TY1
Yeh, HZ1
Tung, CF1
Peng, YC1
Grad, YH1
Seifter, JL1
Levy, BD1
Loscalzo, J1
Lee, SJ1
Jung, MK1
Kim, SK1
Jang, BI1
Lee, SH1
Kim, KO1
Kim, ES1
Cho, KB1
Park, KS1
Kim, EY1
Jung, JT1
Kwon, JG1
Lee, JH1
Yang, CH1
Park, CK1
Seo, HE1
Jeon, SW1
Kahn, DE1
Ferraro, N1
Benveniste, RJ1
Levy, IG1
Pim, CP1
Schaeffner, ES1
Hartness, S1
Juvela, S2
Diener, HC1
Treiber, G1
Schwabe, M1
Ammon, S1
Walker, S1
Klotz, U1
Malfertheiner, P1
Joshipura, KJ1
Wand, HC1
Merchant, AT1
Scranton, R1
Sesso, HD1
Stampfer, MJ5
Levenson, JW1
Wazaify, M1
Kennedy, S1
McElnay, JC1
Wilcox, CM1
Cryer, B1
Triadafilopoulos, G1
Wu, T1
Liu, J1
Stutz, G1
Zamudio, J1
Santillán, ME1
Vincenti, L1
de Cuneo, MF1
Ruiz, RD1
Odemis, B1
Ataseven, H1
Basar, O1
Ertugrul, I1
Yüksel, O1
Turhan, N1
Jayaprakash, V1
Rigual, NR1
Moysich, KB1
Loree, TR1
Nasca, MA1
Menezes, RJ1
Reid, ME1
Füessl, HS1
Leung, FW1
Piazuelo, E1
Fuentes, J1
García-González, MA1
Jiménez, P1
Lanas, A1
Schubert, TT2
Spector, SL1
Wright, JP1
Marks, IN1
Mee, AS1
Girdwood, AH1
Bornman, PC1
Gilinsky, NH1
Tobias, P1
Lucke, W1
Sirridge, M1
Manciaux, M1
Jeanneret, O1
Booker, JA1
Eke-Okoro, ST1
Walker, AM1
Jick, H1
Lanas, AI1
Remacha, B1
Esteva, F1
Sáinz, R1
Gorelick, PB1
Lee, M1
Schenker, S1
Verhoef, P1
Hennekens, CH7
Malinow, MR1
Kok, FJ1
Willett, WC2
Talley, NJ4
Weaver, AL2
Zinsmeister, AR3
Holtmann, G1
Goebell, H1
Holtmann, M1
Schleck, CD1
Melton, LJ2
Silagy, CA1
McNeil, JJ1
Donnan, GA1
Tonkin, AM1
Worsam, B1
Campion, K1
Ridker, PM2
Vaughan, DE1
Sacks, FM1
Karlowicz, MG1
White, LE1
Robbins, AS1
Manson, JE4
Lee, IM1
Satterfield, S2
Henry, D1
Dobson, A1
Turner, C1
Bologna, SD1
Nensey, Y1
Schubert, AB1
Mascha, EJ1
Ma, CK1
Chong, YY1
Chew, CN1
Koh, ET1
Fock, KM1
Braun, EM1
Camargo, CA1
Glynn, RJ1
Goldhaber, SZ1
de Lorgeril, M1
Salen, P1
Caillat-Vallet, E1
Hanauer, MT1
Barthelemy, JC1
Mamelle, N1
Ma, J1
Giovannucci, E1
Artigas, C1
Fuchs, C1
Rozen, R1
Slattery, ML1
Schaffer, D1
Edwards, SL1
Ma, KN1
Potter, JD1
Martínez, ME1
McPherson, RS1
Levin, B1
Glober, GA1
Gascón Ramón, G1
Bertomeu i Blanch, F1
Baño Aracil, M1
Madrigal, JA1
Farrow, DC1
Vaughan, TL1
Hansten, PD1
Stanford, JL1
Risch, HA1
Gammon, MD1
Chow, WH1
Dubrow, R1
Ahsan, H1
Mayne, ST1
Schoenberg, JB1
West, AB1
Rotterdam, H1
Fraumeni, JF1
Blot, WJ1
Holden, J1
O'Donnell, S1
Brindley, J1
Miles, L1
Nightingale, SL1
Haas, DA1
Hart, RG1
Pearce, LA1
McBride, R1
Rothbart, RM1
Asinger, RW1
Zaridze, D1
Borisova, E1
Maximovitch, D1
Chkhikvadze, V1
Cleland, J1
Milman, N1
Ovesen, L1
Byg, K1
Graudal, N1
Pfau, PR1
Lichenstein, GR1
Kaufman, DW1
Kelly, JP1
Wiholm, BE1
Laszlo, A1
Sheehan, JE1
Koff, RS1
Shapiro, S1
Serebruany, VL2
Lowry, DR2
Fuzailov, SY1
Levine, DJ1
O'Connor, CM1
Gurbel, PA1
Ajani, UA1
Lotufo, PA1
Liu, S1
Saloheimo, P1
Hillbom, M1
Avidan, B1
Sonnenberg, A1
Schnell, TG1
Sontag, SJ1
Kalashnikova, LA1
Nasonov, EL1
Aleksandrova, EN1
Kosheleva, NM1
Reshetniak, TM1
Salozhin, KV1
Abramson, B1
Rainsford, KD1
Emmerson, BT1
Graham, DY1
Davis, RE1
Seixas, FA1
Oddsson, E1
Binder, V1
Thorgeirsson, T1
Jonasson, TA1
Gunnlaugsson, O1
Wulff, M1
Jónasson, K1
Wulff, HR1
Bjarnason, O1
Riis, P1
Lewis, EA1
Aderoju, EA1
Jorgensen, TG2
Gyntelberg, F1
Bock, OA2
Tosteson, H1
Hebert, P1
O'Connor, GT1
Morato, GS1
Lemos, T1
Morato, EF1
Pierach, CA1
Locher, KB1
Mallach, HJ1
Moosmayer, A1
Roine, R1
Gentry, RT1
Hernández-Munõz, R1
Baraona, E1
Lieber, CS1
Brazer, SR1
Tyor, MP1
Pancotto, FS1
Nickl, NJ1
Wildermann, NM1
Harrell, FE1
Pryor, DB1
Fikr, V1
Budka, I1
Stika, L1
Walker, P1
Luther, J1
Samloff, IM1
Feldman, M1
McIntosh, JH1
Byth, K1
Piper, DW1
Chapman, BL1
Duggan, JM1
Johnson, KG1
Donnelly, JH1
Scheble, R1
Wine, RL1
Weitman, M1
Johnston, SJ1
Jones, PF1
Kyle, J1
Needham, CD1
Yamagata, S1
Ishimori, A1
Langman, MJ1
Alp, MH2
Court, JH1
Grant, AK2
Christensen, JK1
Fischer, PA1
Strandbygaard, N1
Hislop, IG1
Gillies, M1
Skyring, A1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aspirin/Folate Prevention of Large Bowel Polyps[NCT00272324]Phase 2/Phase 31,121 participants Interventional1992-02-29Completed
[NCT00005182]50,000 participants (Actual)Observational1985-12-31Completed
Treatment of Periodontal Disease in Patients With Acute Myocardial Infarction: Randomized Controlled Trial[NCT02543502]54 participants (Actual)Interventional2012-08-31Completed
[NCT00000500]Phase 30 participants Interventional1981-09-30Completed
Mesh-Reduced Sling For Treating Stress Urinary Incontinence, Efficacy and Durability Trial[NCT05842005]15 participants (Anticipated)Interventional2023-01-01Recruiting
A Multi-center Study to Assess the Outcomes of Stapled Trans-Anal Rectal Resection (STARR) in the Treatment of Obstructed Defecation Syndrome (ODS)[NCT00256984]Phase 475 participants (Actual)Interventional2005-10-01Completed
Impact of Folates in the Care of the Male Infertility[NCT01407432]Phase 3162 participants (Actual)Interventional2011-11-30Completed
Barrett's Esophagus Study (BEST) Trial - a Multi-Center and Endoscopic Outcomes Project[NCT00586404]1,250 participants (Actual)Observational2007-11-30Terminated (stopped due to lack of enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Maximum Change in Subject-reported Assessment of Symptom Severity and Frequency (PAC SYM).

Assessed as patient-reported assessment of symptom severity and frequency (PAC-SYM)associated with constipation. Patient response options are absent, mild, moderate, severe, and very severe.12 questions relate to severity, 8 questions relate to frequency of symptoms. The lower the score, the less severe the symptoms. Sizing consistent with primary outcome; analysis was per-protocol. (NCT00256984)
Timeframe: Baseline, 6 months

Interventionunits on a scale (Mean)
Stapled Trans-Anal Rectal Resection (STARR)1.43

PAC QOL Patient Assessment of Constipation (Overall)

PAC-QOL is Patient Assessment of Constipation, Quality of Life. The instrument consists of 28 questions on a 0-4 scale. A lower score indicates better quality of life. The score is a number without units.Change from baseline in patient assessment of constipation in quality of life as measured by the PAC QOL instrument score. The questions are designed to measure the impact constipation has had on daily life during the week prior to the subject visit. Sizing was consistent with the primary outcome; analysis was per-protocol (NCT00256984)
Timeframe: Baseline, 12 months

Interventionunits on a scale (Mean)
Stapled Trans-Anal Rectal Resection (STARR)0.95

Percentage of Change (Reduction) in Total ODS Symptom Composite Score From Baseline to One Year Post Procedure

The primary endpoint used to assess effectiveness of STARR for treatment of ODS was the percentage of change in total ODS symptom composite score (0=worst, 24=best) 1 year after completion of the procedure. (NCT00256984)
Timeframe: one year from Baseline

Interventionpercentage of change (Mean)
Stapled Trans-Anal Rectal Resection (STARR)60.8

Percentage of Change in ODS Symptom Composite Score From Baseline at 1 Month Post Procedure

Percentage of change in Obstructive Defecation Syndrome (ODS) symptom composite score from baseline at 1 month post procedure. This score is based on a series of questions designed to understand the extent ODS effects an individual's daily lifestyle (0 is worst score, 24 is best score). Sizing consistent with primary outcome; analysis was per-protocol. (NCT00256984)
Timeframe: Baseline, 1 month post procedure

Interventionpercentage of change (Mean)
Stapled Trans-Anal Rectal Resection (STARR)-50.7

Percentage of Change in ODS Symptom Composite Score From Baseline at 6 Months (0 is Worst Score, 24 is Best Score)

The primary endpoint used to assess effectiveness of STARR for treatment of ODS was the percentage of change in total ODS symptom composite score (0=worst, 24=best) 1 year after completion of the procedure. (NCT00256984)
Timeframe: Baseline, 6 months post procedure

Interventionpercentage of change (Mean)
Stapled Trans-Anal Rectal Resection (STARR)-57.0

SF-12 QOL Change (Mental Component) at 12 Months From Baseline

SF 12 change from baseline, mental component. The SF-12 is a validated 12 question quality-of-life questionnaire. The SF-12 extracts 12 items from the SF-36 questionnaire in two six-item subscales, PCS (physical functioning) and MCS (emotional functioning). The SF-36 scores range from 0 (maximum impairment) to 100 (no impairment), the SF-12 scores range from 10 (maximum impairment) to 70 (no impairment). For this study, the endpoint is the percentage of change from baseline over 12 months post procedure. (NCT00256984)
Timeframe: Baseline, 12 months

Interventionunits on a scale (Mean)
Stapled Trans-Anal Rectal Resection (STARR)4.83

SF-12 QOL Change From Baseline (Physical Component)at 12 Months

The SF-12 is a validated 12 question quality-of-life questionnaire. The SF-12 extracts 12 items from the SF-36 questionnaire in two six-item subscales, PCS (physical functioning) and MCS (emotional functioning). The SF-12 scores can range from 10 (maximum impairment) to 70 (no impairment). For this study, the endpoint is the percentage of change from baseline over 12 months post procedure. (NCT00256984)
Timeframe: Baseline, 12 Months

Interventionunits on a scale (Mean)
Stapled Trans-Anal Rectal Resection (STARR)6.32

Reviews

19 reviews available for aspirin and Alcohol Drinking

ArticleYear
Recent advances in clinical practice: colorectal cancer chemoprevention in the average-risk population.
    Gut, 2020, Volume: 69, Issue:12

    Topics: Alcohol Drinking; Allium; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Caffeine;

2020
Lifestyle and Environmental Approaches for the Primary Prevention of Hepatocellular Carcinoma.
    Clinics in liver disease, 2020, Volume: 24, Issue:4

    Topics: Alcohol Drinking; Aspirin; Carcinoma, Hepatocellular; Chronic Disease; Diabetes Mellitus, Type 2; Di

2020
Lifestyle interventions can reduce the risk of Barrett's esophagus: a systematic review and meta-analysis of 62 studies involving 250,157 participants.
    Cancer medicine, 2021, Volume: 10, Issue:15

    Topics: Adenocarcinoma; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; B

2021
Misconceptions and Facts About Atrial Fibrillation.
    The American journal of medicine, 2015, Volume: 128, Issue:9

    Topics: Administration, Oral; Alcohol Drinking; Anticoagulants; Aspirin; Asymptomatic Diseases; Atrial Fibri

2015
Risk factors for gastrointestinal complications in aspirin users: review of clinical and experimental data.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:10

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Risk Factors; Smoking; S

2008
Update in treatment of peptic ulcer disease.
    Missouri medicine, 1984, Volume: 81, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Aluminum; Antacids; Anti-Ulcer Agents; Aspirin; Bismuth; Cimetidine;

1984
Reciprocal relationship between pregnancy and pulmonary disease. State of the art.
    Chest, 1984, Volume: 86, Issue:3 Suppl

    Topics: Adrenergic beta-Agonists; Alcohol Drinking; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Infecti

1984
Stroke prevention.
    Archives of neurology, 1995, Volume: 52, Issue:4

    Topics: Alcohol Drinking; Aspirin; Carotid Stenosis; Cerebrovascular Disorders; Clinical Trials as Topic; Di

1995
[Diet factors and risk of the development of colorectal cancer].
    Klinichna khirurhiia, 1996, Issue:6

    Topics: Adult; Aged; Alcohol Drinking; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium, D

1996
[Intervention in risk factors and protection of target organs].
    Anales de medicina interna (Madrid, Spain : 1984), 1997, Volume: 14, Issue:9

    Topics: Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Diabetes Complications; Diabetes Mellitus; Est

1997
Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series.
    Journal of the American Dental Association (1939), 1999, Volume: 130, Issue:3

    Topics: Acetaminophen; Age Factors; Alcohol Drinking; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agen

1999
Travelling with heart disease.
    The Practitioner, 1998, Volume: 242, Issue:1583

    Topics: Alcohol Drinking; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Dehydration; Diet; Heart Diseas

1998
Stroke. Preemptive strikes.
    Harvard health letter, 2000, Volume: 25, Issue:6

    Topics: Alcohol Drinking; Aspirin; Female; Hormone Replacement Therapy; Humans; Hypercholesterolemia; Hypert

2000
Ophthalmology. What you can do to protect your eyes.
    Harvard health letter, 2001, Volume: 26, Issue:12

    Topics: Alcohol Drinking; Aspirin; Eye Injuries; Eye Protective Devices; Fibrinolytic Agents; Glaucoma; Huma

2001
Risk factors and primary prevention of ischemic heart disease in women.
    The Canadian journal of cardiology, 2001, Volume: 17 Suppl D

    Topics: Alcohol Drinking; Antioxidants; Aspirin; Diabetes Complications; Exercise; Female; Humans; Hyperlipi

2001
The biochemical pathology of aspirin-induced gastric damage.
    Agents and actions, 1975, Volume: 5, Issue:4

    Topics: Age Factors; Alcohol Drinking; Animals; Anti-Inflammatory Agents; Ascorbic Acid Deficiency; Aspirin;

1975
The primary prevention of myocardial infarction.
    The New England journal of medicine, 1992, May-21, Volume: 326, Issue:21

    Topics: Alcohol Drinking; Aspirin; Blood Glucose; Cholesterol; Estrogen Replacement Therapy; Female; Humans;

1992
[Chronic gastritis caused by exogenous factors].
    Saishin igaku. Modern medicine, 1968, Oct-10, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Age Factors; Alcohol Drinking; Aspirin; Carcinogens; Chronic Disease; Female; Flu

1968
Epidemiological evidence for the association of aspirin and acute gastrointestinal bleeding.
    Gut, 1970, Volume: 11, Issue:7

    Topics: Alcohol Drinking; Animals; Ascorbic Acid Deficiency; Aspirin; Gastrointestinal Hemorrhage; Hematemes

1970

Trials

17 trials available for aspirin and Alcohol Drinking

ArticleYear
The preventive effects of low-dose enteric-coated aspirin tablets on the development of colorectal tumours in Asian patients: a randomised trial.
    Gut, 2014, Volume: 63, Issue:11

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Alcohol Drinking; Anticarcinogenic Agents; Aspirin; Colonic Ne

2014
Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:8

    Topics: Adenoma; Alcohol Drinking; Aspirin; Chemoprevention; Colorectal Neoplasms; Double-Blind Method; Fema

2008
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:4

    Topics: Adenoma; Alcohol Drinking; Aspirin; Colon; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; CpG Is

2009
Alcohol consumption and functional outcome after stroke in men.
    Stroke, 2010, Volume: 41, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Cohort Studies; Follow-Up Studies; Humans

2010
Predictors of 14-year changes in the total cholesterol to high-density lipoprotein cholesterol ratio in men.
    American heart journal, 2004, Volume: 147, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Body Weight; Cholesterol;

2004
Ranitidine in the treatment of gastric ulceration.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Jan-30, Volume: 61, Issue:5

    Topics: Aged; Alcohol Drinking; Antacids; Anti-Ulcer Agents; Aspirin; Cimetidine; Clinical Trials as Topic;

1982
A prospective study of plasma homocyst(e)ine and risk of ischemic stroke.
    Stroke, 1994, Volume: 25, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Brain Ischemi

1994
The PACE pilot study: 12-month results and implications for future primary prevention trials in the elderly. (Prevention with low-dose Aspirin of Cardiovascular disease in the Elderly)
    Journal of the American Geriatrics Society, 1994, Volume: 42, Issue:6

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Australia; Blood Pressure; Cardiovascular Diseas

1994
A cross-sectional study of endogenous tissue plasminogen activator, total cholesterol, HDL cholesterol, and apolipoproteins A-I, A-II, and B-100.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 1993, Volume: 13, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Apolipoprotein A-I; Apolipoprotein A-II; Apolipopr

1993
Cigarette smoking and stroke in a cohort of U.S. male physicians.
    Annals of internal medicine, 1994, Mar-15, Volume: 120, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Double-Blind M

1994
Prospective study of moderate alcohol consumption and risk of peripheral arterial disease in US male physicians.
    Circulation, 1997, Feb-04, Volume: 95, Issue:3

    Topics: Adult; Alcohol Drinking; Arteries; Aspirin; beta Carotene; Cardiovascular Diseases; Double-Blind Met

1997
Control of bias in dietary trial to prevent coronary recurrences: The Lyon Diet Heart Study.
    European journal of clinical nutrition, 1997, Volume: 51, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Angiotensin-Converting Enzyme Inhibitors; Anti

1997
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
    Cancer research, 1997, Mar-15, Volume: 57, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Case-Control Studies; Coca

1997
Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation: analysis of 2012 participants in the SPAF I-III clinical trials. The Stroke Prevention in Atrial Fibrillation (SPAF) Investigators.
    Stroke, 1999, Volume: 30, Issue:6

    Topics: Aged; Alcohol Drinking; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cerebrovascula

1999
Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.
    Journal of thrombosis and thrombolysis, 2000, Volume: 9, Issue:3

    Topics: Aged; Alcohol Drinking; Aspirin; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Ethanol; Female;

2000
Alcohol consumption and risk of coronary heart disease by diabetes status.
    Circulation, 2000, Aug-01, Volume: 102, Issue:5

    Topics: Alcohol Drinking; Aspirin; beta Carotene; Cardiovascular Diseases; Coronary Disease; Diabetes Mellit

2000
[Pharmacokinetic interactions between alcohol and acetylsalicylic acid].
    Blutalkohol, 1991, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Ethanol; Female; Humans; Male; Metabolic Clearance Rat

1991

Other Studies

95 other studies available for aspirin and Alcohol Drinking

ArticleYear
A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player.
    Drug and alcohol dependence, 2022, 07-01, Volume: 236

    Topics: Acetylcysteine; Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Animals; Aspirin; Chronic D

2022
Head-to-Head Comparison of the Performance of 17 Risk Models for Predicting Presence of Advanced Neoplasms in Colorectal Cancer Screening.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:9

    Topics: Adenoma; Age Factors; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Area Under Cu

2019
Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation.
    Addiction biology, 2021, Volume: 26, Issue:1

    Topics: Acetylcysteine; Alcohol Drinking; Alcoholism; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspi

2021
Prevalence and sociodemographic determinants of dyspepsia in the general population of Rwanda.
    BMJ open gastroenterology, 2020, Volume: 7, Issue:1

    Topics: Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cos

2020
Aspirin and other nonsteroidal anti-inflammatory drugs, statins and risk of non-Hodgkin lymphoma.
    International journal of cancer, 2021, 08-01, Volume: 149, Issue:3

    Topics: Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Follow-Up S

2021
Assessing Bleeding Risk in Patients Taking Anticoagulants.
    American family physician, 2017, Oct-01, Volume: 96, Issue:7

    Topics: Age Factors; Alcohol Drinking; Anemia; Anticoagulants; Aspirin; Atrial Fibrillation; Decision Suppor

2017
Alcohol-induced respiratory symptoms improve after aspirin desensitization in patients with aspirin-exacerbated respiratory disease.
    International forum of allergy & rhinology, 2018, Volume: 8, Issue:10

    Topics: Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Ind

2018
Preventing cardiovascular disease in New Zealand: making better use of statins but also tobacco control, changing the food supply and other strategies.
    The New Zealand medical journal, 2018, 10-26, Volume: 131, Issue:1484

    Topics: Alcohol Drinking; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Decision Making; Drug C

2018
Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer.
    British journal of cancer, 2013, Mar-19, Volume: 108, Issue:5

    Topics: Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Head and Neck Neop

2013
Proton-pump inhibitors can decrease gastrointestinal bleeding after percutaneous coronary intervention.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Alcohol Drinking; Angina, Stable; Aspirin; Case-Control

2013
Colonic diverticular hemorrhage associated with the use of nonsteroidal anti-inflammatory drugs, low-dose aspirin, antiplatelet drugs, and dual therapy.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:10

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants;

2014
Stroke and bleeding risk co-distribution in real-world patients with atrial fibrillation: the Euro Heart Survey.
    The American journal of medicine, 2014, Volume: 127, Issue:10

    Topics: Age Distribution; Aged; Alcohol Drinking; Anticoagulants; Aspirin; Atrial Fibrillation; Diabetes Com

2014
Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, low-dose aspirin, and antihypertensive drugs: a case-control study.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Antihyper

2015
Impact of Diagnostic Delay and Other Risk Factors on Eosinophilic Esophagitis Phenotype and Esophageal Diameter.
    Journal of clinical gastroenterology, 2016, Volume: 50, Issue:2

    Topics: Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution;

2016
Non-steroidal anti-inflammatory drugs and the risk of head and neck cancer: A case-control analysis.
    International journal of cancer, 2015, Nov-15, Volume: 137, Issue:10

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Female; He

2015
Predictors of advanced colorectal neoplasia at initial and surveillance colonoscopy after positive screening immunochemical faecal occult blood test.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:3

    Topics: Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonoscopy; Colorectal Ne

2016
Etiological Factors in Urgent Gastroduodenal Ulcer.
    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki), 2015, Volume: 36, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroid

2015
A Prospective Study of Alcohol Consumption and Smoking and the Risk of Major Gastrointestinal Bleeding in Men.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Alcohol Drinking; Alcoholic Beverages; Aspirin; Beer; Ethanol; Follow-Up Studies; Gastrointestinal H

2016
Should you screen--or not? The latest recommendations.
    The Journal of family practice, 2008, Volume: 57, Issue:7

    Topics: Adult; Alcohol Drinking; Anemia, Sickle Cell; Aspirin; Chlamydia Infections; Colorectal Neoplasms; F

2008
Combined effect of health behaviours and risk of first ever stroke in 20,040 men and women over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): prospective population study.
    BMJ (Clinical research ed.), 2009, Feb-19, Volume: 338

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; England; Exercise; Female; Fruit; Health Behavior; Humans; I

2009
The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectum.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:8

    Topics: Age Factors; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Body

2009
Uracil misincorporation into DNA and folic acid supplementation.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:1

    Topics: Adenoma; Aged; Alcohol Drinking; Aspirin; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; DN

2010
Dietary, lifestyle, and clinical predictors of lipoprotein-associated phospholipase A2 activity in individuals without coronary artery disease.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Age Factors; Aged; Alcohol Drinking; Antichol

2010
Risk factors and therapeutic response in Chinese patients with peptic ulcer disease.
    World journal of gastroenterology, 2010, Apr-28, Volume: 16, Issue:16

    Topics: Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; China; Endo

2010
Clinical problem-solving. Bitter pills.
    The New England journal of medicine, 2010, Nov-04, Volume: 363, Issue:19

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Diagnosis, Di

2010
A hangover remedy for the holidays?
    Consumer reports, 2011, Volume: 76, Issue:1

    Topics: Alcohol Drinking; Aspirin; Caffeine; Headache; Humans; Pain; Pain Management

2011
[Clinical characteristics of gastroesophageal reflux disease with esophageal injury in korean: focusing on risk factors].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, May-25, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspiri

2011
3 cases of primary intracranial hemorrhage associated with "Molly", a purified form of 3,4-methylenedioxymethamphetamine (MDMA).
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Adult; Alcohol Drinking; Amphetamine-Related Disorders; Anticoagulants; Aspirin; Cerebral Angiograph

2012
An aspirin a day: the allure (and distraction) of chemoprevention.
    Journal of the National Cancer Institute, 2012, Dec-05, Volume: 104, Issue:23

    Topics: Alcohol Drinking; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin

2012
Smoking and the risk of hemorrhagic stroke in men.
    Stroke, 2003, Volume: 34, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Body Mass Ind

2003
Twenty years and counting.
    Journal of the Mississippi State Medical Association, 2003, Volume: 44, Issue:3

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; beta Carotene; Cardiovascular Di

2003
Nonsteroidal anti-inflammatory drugs as risk factors for spontaneous intracerebral hemorrhage and aneurysmal subarachnoid hemorrhage.
    Stroke, 2003, Volume: 34, Issue:6

    Topics: Age Factors; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control

2003
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic

2003
Dyspeptic symptoms associated with Helicobacter pylori infection are influenced by strain and host specific factors.
    Alimentary pharmacology & therapeutics, 2004, Jan-15, Volume: 19, Issue:2

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Cohort Studies; Dyspepsia; Female; Helicobacter Infections;

2004
Periodontal disease and biomarkers related to cardiovascular disease.
    Journal of dental research, 2004, Volume: 83, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Antigens, CD; Aspirin; Biomarkers; C-Reactiv

2004
Periodontal disease and biomarkers related to cardiovascular disease.
    Journal of dental research, 2004, Volume: 83, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Antigens, CD; Aspirin; Biomarkers; C-Reactiv

2004
Periodontal disease and biomarkers related to cardiovascular disease.
    Journal of dental research, 2004, Volume: 83, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Antigens, CD; Aspirin; Biomarkers; C-Reactiv

2004
Periodontal disease and biomarkers related to cardiovascular disease.
    Journal of dental research, 2004, Volume: 83, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Antigens, CD; Aspirin; Biomarkers; C-Reactiv

2004
Prevalence of over-the-counter drug-related overdoses at Accident and Emergency departments in Northern Ireland--a retrospective evaluation.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:1

    Topics: Acetaminophen; Age Factors; Alcohol Drinking; Aspirin; Data Collection; Databases as Topic; Drug Com

2005
Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs.
    The Journal of rheumatology, 2005, Volume: 32, Issue:11

    Topics: Acetaminophen; Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Data Colle

2005
Alcohol and aspirin in combination with dexamethasone causes gastrointestinal bleeding at high altitude.
    Wilderness & environmental medicine, 2006,Spring, Volume: 17, Issue:1

    Topics: Adult; Alcohol Drinking; Altitude; Altitude Sickness; Aspirin; Dexamethasone; Drug Synergism; Gastro

2006
The effect of alcohol, tobacco, and aspirin consumption on seminal quality among healthy young men.
    Archives of environmental health, 2004, Volume: 59, Issue:11

    Topics: Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Infertility, Male

2004
Ulcer in the basis of Zenker's diverticulum mimicking esophageal malignancy.
    Journal of the National Medical Association, 2006, Volume: 98, Issue:7

    Topics: Aged; Alcohol Drinking; Aspirin; Diagnosis, Differential; Diverticulitis; Endoscopy; Esophageal Neop

2006
Chemoprevention of head and neck cancer with aspirin: a case-control study.
    Archives of otolaryngology--head & neck surgery, 2006, Volume: 132, Issue:11

    Topics: Alcohol Drinking; Aspirin; Case-Control Studies; Confidence Intervals; Female; Head and Neck Neoplas

2006
[Family practice highlights of stomach, liver and intestinal reference points. Your arsenal against abdominal problems].
    MMW Fortschritte der Medizin, 2007, Nov-29, Volume: 149, Issue:48

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barrett Esophagus; Family Practi

2007
A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin.
    Clinical therapeutics, 2008, Volume: 30, Issue:1

    Topics: Aged; Alcohol Drinking; Aspirin; Case-Control Studies; Female; Gastrointestinal Hemorrhage; Gene Fre

2008
Laboratory evaluation of the bleeding patient.
    Clinics in laboratory medicine, 1984, Volume: 4, Issue:2

    Topics: Alcohol Drinking; Anti-Bacterial Agents; Aspirin; Bleeding Time; Blood Coagulation Disorders; Blood

1984
[Accidents involving children and adolescents: from epidemiological findings to preventive action].
    Revue d'epidemiologie et de sante publique, 1983, Volume: 31, Issue:4

    Topics: Accident Prevention; Accidents, Home; Accidents, Traffic; Adolescent; Alcohol Drinking; Aspirin; Ath

1983
Haematemesis and melaena in the elderly.
    Age and ageing, 1984, Volume: 13, Issue:1

    Topics: Aged; Alcohol Drinking; Anti-Inflammatory Agents; Aspirin; Esophagitis; Female; Gastritis; Hematemes

1984
The H-reflex studied in the presence of alcohol, aspirin, caffeine, force and fatigue.
    Electromyography and clinical neurophysiology, 1982, Volume: 22, Issue:7

    Topics: Adult; Alcohol Drinking; Aspirin; Caffeine; H-Reflex; Humans; Muscle Contraction; Reflex, Monosynapt

1982
Predictors of bleeding during heparin therapy.
    JAMA, 1980, Sep-12, Volume: 244, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Dose-Response Relationship, Drug; Epistaxis; Female; Hematom

1980
Risk factors associated with refractory peptic ulcers.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Female; Gastric

1995
Alcohol and analgesics--mix extraordinaire.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:3

    Topics: Acetaminophen; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug

1994
Smoking, alcohol, and nonsteroidal anti-inflammatory drugs in outpatients with functional dyspepsia and among dyspepsia subgroups.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases, Functional; Dy

1994
Dyspepsia in healthy blood donors. Pattern of symptoms and association with Helicobacter pylori.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Alcohol Drinking; Analgesics; Antibodies, Bacterial; Aspirin; Blood Donors; Colon

1994
Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups: lack of an association in a community.
    Gut, 1994, Volume: 35, Issue:5

    Topics: Acetaminophen; Adult; Age Factors; Alcohol Drinking; Analgesics; Aspirin; Dyspepsia; Female; Humans;

1994
Severe intracranial hemorrhage in a term neonate associated with maternal acetylsalicylic acid ingestion.
    Clinical pediatrics, 1993, Volume: 32, Issue:12

    Topics: Alcohol Drinking; Aspirin; Cerebral Hemorrhage; Female; Heartburn; Humans; Infant, Newborn; Male; Ma

1993
Functional constipation and outlet delay: a population-based study.
    Gastroenterology, 1993, Volume: 105, Issue:3

    Topics: Adult; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Constipatio

1993
Functional constipation and outlet delay: a population-based study.
    Gastroenterology, 1993, Volume: 105, Issue:3

    Topics: Adult; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Constipatio

1993
Functional constipation and outlet delay: a population-based study.
    Gastroenterology, 1993, Volume: 105, Issue:3

    Topics: Adult; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Constipatio

1993
Functional constipation and outlet delay: a population-based study.
    Gastroenterology, 1993, Volume: 105, Issue:3

    Topics: Adult; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Constipatio

1993
Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs.
    Gastroenterology, 1993, Volume: 105, Issue:4

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Age Factors; Aged; Aged, 80 and ove

1993
Ulcer risk factors: interactions between Helicobacter pylori infection, nonsteroidal use, and age.
    The American journal of medicine, 1993, Volume: 94, Issue:4

    Topics: Adult; Age Factors; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Fema

1993
A comparison of clinical and endoscopic features of bleeding and non-bleeding peptic ulcer in Singapore.
    Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:4

    Topics: Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastroin

1996
Are dietary factors involved in DNA methylation associated with colon cancer?
    Nutrition and cancer, 1997, Volume: 28, Issue:1

    Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studie

1997
A case-control study of dietary intake and other lifestyle risk factors for hyperplastic polyps.
    Gastroenterology, 1997, Volume: 113, Issue:2

    Topics: Adenoma; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Mass Index;

1997
Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:2

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal;

1998
Aspirin treatment.
    Journal of advanced nursing, 1998, Volume: 27, Issue:3

    Topics: Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Humans; Hypertension; Patient Education as Top

1998
Analysis of 1263 deaths in four general practices.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 1998, Volume: 48, Issue:432

    Topics: Accidental Falls; Adolescent; Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal

1998
From the Food and Drug Administration.
    JAMA, 1998, Dec-02, Volume: 280, Issue:21

    Topics: Alcohol Drinking; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asp

1998
Aspirin protects against gastric cancer: results of a case-control study from Moscow, Russia.
    International journal of cancer, 1999, Aug-12, Volume: 82, Issue:4

    Topics: Adenocarcinoma; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma,

1999
Iron status in Danes updated 1994. I: prevalence of iron deficiency and iron overload in 1332 men aged 40-70 years. Influence Of blood donation, alcohol intake, and iron supplementation.
    Annals of hematology, 1999, Volume: 78, Issue:9

    Topics: Adult; Aged; Alcohol Drinking; Anemia, Iron-Deficiency; Antacids; Aspirin; Blood Donors; Body Weight

1999
NSAIDs and alcohol: never the twain shall mix?
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase

1999
The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Acute Disease; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Contro

1999
Take an aspirin or have a drink: antecedent aspirin and moderate alcohol consumption similarly affect baseline platelet characteristics in patients with acute myocardial infarction.
    Thrombosis and haemostasis, 2000, Volume: 84, Issue:5

    Topics: Alcohol Drinking; Aspirin; Humans; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation

2000
Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people.
    Stroke, 2001, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Cerebral Hemorrhage; Comorbidity; Epileps

2001
Risk factors for erosive reflux esophagitis: a case-control study.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:1

    Topics: Adult; Age Distribution; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C

2001
[Antibodies to phospholipids and ischemic disorders of cerebral circulation in young age].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1997, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Age Factors; Alcohol Drinking; Antibodies, Antiphospholipid; Anticoagulants; Anti

1997
Acquired causes of hyperuricaemia.
    Australian and New Zealand journal of medicine, 1978, Volume: 8 Suppl 1

    Topics: Alcohol Drinking; Aspirin; Diet; Energy Intake; Gout; Humans; Kidney Diseases; Phenylbutazone; Uric

1978
Acute upper-gastrointestinal hemorrhage. New observations on an old problem.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:1

    Topics: Alcohol Drinking; Aspirin; Duodenal Ulcer; Esophageal and Gastric Varices; Esophagoscopy; Gastritis;

1978
Drug/alcohol interactions: avert potential dangers.
    Geriatrics, 1979, Volume: 34, Issue:10

    Topics: Aged; Aging; Alcohol Drinking; Alcoholism; Antidepressive Agents, Tricyclic; Aspirin; California; Di

1979
A prospective comparative study of clinical and pathological characteristics in Icelandic and Danish patients with gastric ulcer, duodenal ulcer, and X-ray negative dyspepsia. II. Histological results.
    Scandinavian journal of gastroenterology, 1978, Volume: 13, Issue:4

    Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspirin; Denmark; Duodenal Ulcer; Dyspepsia; Female; Gas

1978
Factors in the aetiology of chronic duodenal ulcer in Ibadan.
    Tropical and geographical medicine, 1978, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Aspirin; Child; Diet; Duodenal Ulcer; Female; Food; Human

1978
Occurence of peptic ulcer disease in Copenhagen males age 40-59. Life incidence and one-year incidence correlated to environmental factors, life habits, physical factors, and concomitant disease.
    Danish medical bulletin, 1976, Volume: 23, Issue:1

    Topics: Adult; Alcohol Drinking; Aspirin; Denmark; Drug-Related Side Effects and Adverse Reactions; Follow-U

1976
Alcohol, aspirin, depression, smoking, stress and the patient with a gastric ulcer.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, Feb-28, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Aspirin; Chronic Disease; Depression; Ethnicity; Female;

1976
Effects of indomethacin, aspirin, and acetaminophen on ethanol diuresis in rats.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:1

    Topics: Acetaminophen; Alcohol Drinking; Animals; Aspirin; Diuresis; Dose-Response Relationship, Drug; Femal

1992
Alcohol and mortality.
    Lancet (London, England), 1991, Oct-26, Volume: 338, Issue:8774

    Topics: Alcohol Drinking; Aspirin; Cause of Death; Coronary Disease; Humans; Male

1991
[Alcohol consumption and coronary sclerosis].
    Deutsche medizinische Wochenschrift (1946), 1992, Jan-03, Volume: 117, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Coronary Disease; Humans; Male; Middle Aged; Prospective Stu

1992
Aspirin increases blood alcohol concentrations in humans after ingestion of ethanol.
    JAMA, 1990, Nov-14, Volume: 264, Issue:18

    Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Aspirin; Ethanol; Gastric Mucosa; Humans; M

1990
Studies of gastric ulcer disease by community-based gastroenterologists.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:7

    Topics: Abdominal Pain; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastroin

1990
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
    Ceskoslovenske zdravotnictvi, 1988, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combina

1988
Life events stress and psychosocial factors in men with peptic ulcer disease. II. Relationships with serum pepsinogen concentrations and behavioral risk factors.
    Gastroenterology, 1988, Volume: 94, Issue:2

    Topics: Acetaminophen; Alcohol Drinking; Aspirin; Behavior; Coffee; Humans; Life Change Events; Male; Pepsin

1988
Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms.
    Gut, 1985, Volume: 26, Issue:8

    Topics: Acetaminophen; Alcohol Drinking; Analgesics; Anti-Inflammatory Agents; Aspirin; Chronic Disease; Fem

1985
Environmental factors and the Australian gastric ulcer change.
    The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Alcohol Drinking; Aspirin; Australia; Disabled Persons; Duodenal Ulc

1969
Survey of adolescent drug use. I. Sex and grade distribution.
    American journal of public health, 1971, Volume: 61, Issue:12

    Topics: Adolescent; Age Factors; Alcohol Drinking; Amphetamine; Aspirin; Barbiturates; Cannabis; Cocaine; De

1971
Epidemiology and course of gastrointestinal haemorrhage in North-east Scotland.
    British medical journal, 1973, Sep-29, Volume: 3, Issue:5882

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Blood Group Antigens; Duodenal Ulcer; Female; Gastritis; Gas

1973
The management of a patient with a duodenal ulcer.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Nov-25, Volume: 46, Issue:47

    Topics: Adult; Alcohol Drinking; Alkalies; Aspirin; Chronic Disease; Diet Therapy; Duodenal Ulcer; Humans; P

1972
Personality pattern and emotional stress in the genesis of gastric ulcer.
    Gut, 1970, Volume: 11, Issue:9

    Topics: Aggression; Alcohol Drinking; Anxiety; Aspirin; Female; Humans; Life Style; Male; Personality; Perso

1970
[Psychiatric and gastroenterological evaluation of patients with duodenal ulcer confirmed at operation. 100 patients studied by preoperative psychiatric interview and enlarged histamine test with special reference to the relation between psychic factors a
    Nordisk medicin, 1970, Oct-29, Volume: 83, Issue:44

    Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Aspirin; Character; Child; Drinking Behavior

1970
Gastric ulcer in South Australia 1954-1963. I. Epidemiological factors.
    The Medical journal of Australia, 1970, Dec-12, Volume: 2, Issue:24

    Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspirin; Australia; Humans

1970
Gastric ulcer, duodenal ulcer and gastric carcinoma: a case-control study of certain social and environmental factors.
    The Medical journal of Australia, 1968, Dec-21, Volume: 2, Issue:25

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Australia; Divorce; Duodenal Ulcer; Educational Status; Fami

1968