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aspirin and Alcohol Abuse

aspirin has been researched along with Alcohol Abuse in 39 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the relative risk for peptic ulcer disease that is associated with the use of nonaspirin nonsteroidal anti-inflammatory drugs."5.07Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. ( Daugherty, JR; Griffin, MR; Piper, JM; Ray, WA; Snowden, M, 1991)
" There were five chronic alcoholics, one aspirin abuser, one severely burned patient, and one patient with sepsis."3.65Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis. ( Aust, JB; McFee, AS; Rittenhouse, M, 1976)
"Recurrent gastrojejunal ulceration is reported in three patients with histamine-fast achlorhydria."3.65Marginal ulcer in achlorhydric patients. ( Hirschowitz, BI; Tauxe, RV; Wright, LF, 1975)
"Smoking, alcohol abuse, and obesity were more common in patients with ST elevation myocardial infarction (STEMI) (P < 0."1.42Management of acute coronary syndromes in a developing country; time for a paradigm shift? an observational study. ( Bandara, R; De Silva, C; Galgomuwa, MP; Medagama, A, 2015)
"It is concluded that the groups with alcohol abuse who used hepatotoxic drugs showed a picture of cortical changes (wide transport sulci and clear-cut or high-grade cortical changes) and also of subcortical aberrations, expressed as an increased widening of the third ventricle."1.28Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population. ( Mützell, S, 1992)
"Stress gastritis was present in 10% of patients, all of whom were in the intensive care unit."1.27Endoscopic diagnosis of gastritis: causative factors in 100 patients. ( Behler, E; Elta, G; Nostrant, T; Wilson, J, 1987)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199027 (69.23)18.7374
1990's6 (15.38)18.2507
2000's1 (2.56)29.6817
2010's3 (7.69)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Ezquer, F2
Quintanilla, ME2
Morales, P2
Santapau, D2
Munita, JM1
Moya-Flores, F1
Ezquer, M2
Herrera-Marschitz, M2
Israel, Y2
Berríos-Cárcamo, P1
Olivares, B1
El-Kharashi, OA1
El-Din Aly El-Waseef, DA1
Nabih, ES1
Mohamed, DI1
Medagama, A1
Bandara, R1
De Silva, C1
Galgomuwa, MP1
Farhadi, A1
Keshavarzian, A1
Kwasny, MJ1
Shaikh, M1
Fogg, L1
Lau, C1
Fields, JZ1
Forsyth, CB1
Dare, WN1
Noronha, CC1
Kusemiju, OT1
Okanlawon, OA1
LEVRAT, M1
LAMBERT, R1
PASQUIER, J1
Becker, CE1
Marco, LA1
Randels, PM1
Ryser, PE1
Alberhasky, M1
Nichols, GR1
Trewby, PN1
Malpass, TW1
Harker, LA1
Zimmerman, HJ1
Hochain, P1
Berkelmans, I1
Czernichow, P1
Duhamel, C1
Tranvouez, JL1
Lerebours, E1
Colin, R1
Stachura, J1
Konturek, SJ1
Brzozowski, T1
Konturek, J1
Domschke, W1
Thome, J1
Zhang, J1
Davids, E1
Foley, P1
Weijers, HG1
Wiesbeck, GA1
Böning, J1
Riederer, P1
Gerlach, M1
Hall, WH1
My, TQ1
Welsh, JD1
Hamptom, JW1
Seixas, FA1
Miyoshi, A1
Fenner, H1
Demanet, JC1
Rittenhouse, M1
McFee, AS1
Aust, JB1
Tauxe, RV1
Wright, LF1
Hirschowitz, BI1
Mützell, S1
Hale, RL1
Randall, CL1
Becker, HC1
Turner, KP1
Griffin, MR1
Piper, JM1
Daugherty, JR1
Snowden, M1
Ray, WA1
Segarnick, DJ1
Cordasco, DM1
Rotrosen, J1
Oyler, JJ1
Elta, G1
Behler, E1
Nostrant, T1
Wilson, J1
Wedgwood, KR1
Adler, G1
Kern, H1
Reber, HA1
Dryburgh, DR1
Lataste, J1
Le Picard, P1
Liu, T1
Smith, GW1
Rankin, JT1
Murray, RM1
Iturriaga, H1
Pereda, T1
Pino, ME1
Ugarte, G1
Winawer, SJ1
Bejar, J1
McCray, RS1
Zamcheck, N1
Kessel, N1
Kellett, P1

Reviews

5 reviews available for aspirin and Alcohol Abuse

ArticleYear
Drug-induced peptic ulcer and upper gastrointestinal bleeding.
    British journal of hospital medicine, 1980, Volume: 23, Issue:2

    Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Aspirin; Diuretics; Emepronium; Female; Gastrointestin

1980
Acquired disorders of platelet function.
    Seminars in hematology, 1980, Volume: 17, Issue:4

    Topics: Alcoholism; Amyloidosis; Anti-Bacterial Agents; Aspirin; Blood Platelet Disorders; Blood Platelets;

1980
Pathologic basis of gastric mucosal adaptation to topical injury.
    Journal of gastroenterology, 1995, Volume: 30, Issue:3

    Topics: Adaptation, Physiological; Alcoholism; Animals; Aspirin; Gastric Mucosa; Humans; Regeneration; Risk

1995
[A recent view of chronic gastritis (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1976, Volume: 65, Issue:5

    Topics: Alcoholism; Aspirin; Bile; Chronic Disease; Follow-Up Studies; Gastric Juice; Gastritis; Humans

1976
Vitamin C and chiropractic.
    Journal of manipulative and physiological therapeutics, 1985, Volume: 8, Issue:2

    Topics: Age Factors; Alcoholism; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ascorbic Acid; As

1985

Trials

1 trial available for aspirin and Alcohol Abuse

ArticleYear
Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons.
    Annals of internal medicine, 1991, Feb-15, Volume: 114, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alcoholism; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1991

Other Studies

33 other studies available for aspirin and Alcohol Abuse

ArticleYear
A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player.
    Drug and alcohol dependence, 2022, 07-01, Volume: 236

    Topics: Acetylcysteine; Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Animals; Aspirin; Chronic D

2022
Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation.
    Addiction biology, 2021, Volume: 26, Issue:1

    Topics: Acetylcysteine; Alcohol Drinking; Alcoholism; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspi

2021
Targeting NLRP3 inflammasome via acetylsalicylic acid: Role in suppressing hepatic dysfunction and insulin resistance induced by atorvastatin in naïve versus alcoholic liver in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Alcoholism; Animals; Aspirin; Atorvastatin; Bile Acids and Salts; Caspase 8; Hepatocytes; Inflammaso

2018
Management of acute coronary syndromes in a developing country; time for a paradigm shift? an observational study.
    BMC cardiovascular disorders, 2015, Oct-24, Volume: 15

    Topics: Acute Coronary Syndrome; Aged; Alcoholism; Angina, Unstable; Aspirin; Delayed Diagnosis; Developing

2015
Effects of aspirin on gastroduodenal permeability in alcoholics and controls.
    Alcohol (Fayetteville, N.Y.), 2010, Volume: 44, Issue:5

    Topics: Adult; Alcoholism; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Digestive System; Female; Gastr

2010
The effect of ethanol on spermatogenesis and fertility in male Sprague-Dawley rats pretreated with acetylsalicylic acid.
    The Nigerian postgraduate medical journal, 2002, Volume: 9, Issue:4

    Topics: Alcoholism; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygena

2002
[RESEARCH OF ETIOLOGICAL FACTORS IN GASTRODUODENAL ULCER AND ITS COMPLICATIONS].
    Minerva medica, 1964, Mar-14, Volume: 55

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alcoholism; Aspirin; Blood Circulation; Body C

1964
The alcoholic patient as a toxic emergency.
    Emergency medicine clinics of North America, 1984, Volume: 2, Issue:1

    Topics: 1-Propanol; Acidosis; Alcoholic Intoxication; Alcoholism; Aspirin; Blood Glucose; Diagnosis, Differe

1984
Drug interactions in alcoholic patients.
    The Hillside journal of clinical psychiatry, 1981, Volume: 3, Issue:1

    Topics: Alcoholism; Anesthetics; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antihypertensi

1981
Students and drug abuse, 1974 and 1980.
    The Journal of school health, 1983, Volume: 53, Issue:7

    Topics: Adolescent; Alcoholism; Aspirin; Child; Diazepam; Humans; Marijuana Abuse; Methaqualone; Students; S

1983
Fatal hemorrhage from minor trauma following massive salicylate ingestion.
    The American journal of forensic medicine and pathology, 1984, Volume: 5, Issue:2

    Topics: Alcoholism; Aspirin; Death, Sudden; Hemorrhage; Humans; Lung Diseases; Male; Mediastinal Diseases; M

1984
Effects of aspirin and acetaminophen on the liver.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Adolescent; Adult; Alcoholism; Arthritis, Juvenile; Aspirin; Child; Female; Humans; L

1981
Which patients taking non-aspirin non-steroidal anti-inflammatory drugs bleed? A case-control study.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Alcoholism; Anti-Inflammatory Agents, Non-Steroida

1995
Evidence for increased oxidative stress in alcohol-dependent patients provided by quantification of in vivo salicylate hydroxylation products.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:1

    Topics: Adult; Alcoholism; Aspirin; Biotransformation; Female; Humans; Hydroxybenzoates; Hydroxyl Radical; L

1997
Hemostatic defect in endoscoped upper gut bleeding.
    Acta hepato-gastroenterologica, 1978, Volume: 25, Issue:1

    Topics: Alcoholism; Aspirin; Blood Coagulation Tests; Gastritis; Gastrointestinal Hemorrhage; Humans; Liver

1978
Drug/alcohol interactions: avert potential dangers.
    Geriatrics, 1979, Volume: 34, Issue:10

    Topics: Aged; Aging; Alcohol Drinking; Alcoholism; Antidepressive Agents, Tricyclic; Aspirin; California; Di

1979
[The problems of the various characteristics of drug abuse (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, May-14, Volume: 118, Issue:20

    Topics: Alcoholism; Analgesics; Animals; Aspirin; Humans; Hypnotics and Sedatives; Nonprescription Drugs; Pr

1976
[Serious complications of current treatments].
    Bruxelles medical, 1975, Volume: 55, Issue:10

    Topics: Acidosis; Adolescent; Aged; Alcoholism; Antihypertensive Agents; Aspirin; Diuretics; Drug-Related Si

1975
Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis.
    Southern medical journal, 1976, Volume: 69, Issue:7

    Topics: Adult; Age Factors; Alcoholism; Aspirin; Burns; Child, Preschool; Female; Gastrectomy; Gastritis; Ga

1976
Marginal ulcer in achlorhydric patients.
    Annals of surgery, 1975, Volume: 181, Issue:4

    Topics: Achlorhydria; Aged; Alcoholism; Aspirin; Gastrectomy; Gastric Acidity Determination; Gastric Juice;

1975
Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population.
    Upsala journal of medical sciences, 1992, Volume: 97, Issue:2

    Topics: Adult; Aged; Alcoholism; Analgesics; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Antipyrine; Aspiri

1992
Aspirin pretreatment reduces ethanol withdrawal severity in a mouse model of binge drinking.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: Alcoholism; Animals; Aspirin; Body Weight; Disease Models, Animal; Ethanol; Male; Mice; Mice, Inbred

1992
Prostanoid modulation (mediation?) of certain behavioral effects of ethanol.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: Alcoholism; Alprostadil; Animals; Aspirin; Brain; Ethanol; Fatty Acids; Fatty Acids, Essential; Fatt

1985
Drugs and alcohol--a dentist's story of addiction.
    Florida dental journal, 1986,Winter, Volume: 57, Issue:4

    Topics: Alcoholism; Aspirin; Caffeine; Dentists; Dextropropoxyphene; Drug Combinations; Humans; Male; Oxycod

1986
Endoscopic diagnosis of gastritis: causative factors in 100 patients.
    Southern medical journal, 1987, Volume: 80, Issue:9

    Topics: Adult; Aged; Alcoholism; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Duodeniti

1987
Effects of oral agents on pancreatic duct permeability. A model of acute alcoholic pancreatitis.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:10

    Topics: Acute Disease; Alcoholism; Animals; Aspirin; Cats; Cell Membrane Permeability; Ethanol; Pancreatic D

1986
[Upper digestive hemorrhages due to gastritis or of unknown cause. (Apropos of 140 cases)].
    Journal de chirurgie, 1973, Volume: 106, Issue:6

    Topics: Alcoholism; Aspirin; Endoscopy; Esophageal and Gastric Varices; Fiber Optic Technology; Gastrectomy;

1973
Renal pelvic tumour associated with analgesic abuse.
    Canadian Medical Association journal, 1972, Oct-21, Volume: 107, Issue:8

    Topics: Adenocarcinoma; Aged; Alcoholism; Analgesics; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hu

1972
The origins of analgesic nephropathy.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 123, Issue:572

    Topics: Adult; Affective Symptoms; Aged; Alcoholism; Analgesics; Antipyrine; Aspirin; Codeine; Creatinine; F

1973
Relationship between liver catalase activity and ethanol metabolism.
    Archivos de biologia y medicina experimentales, 1973, Volume: 9, Issue:1,2,3

    Topics: Administration, Oral; Alcoholism; Animals; Aspirin; Catalase; Ethanol; Female; Humans; Liver; Male;

1973
Hemorrhagic gastritis. Importance of associated chronic gastritis.
    Archives of internal medicine, 1971, Volume: 127, Issue:1

    Topics: Acute Disease; Alcoholism; Aspirin; Atrophy; Biopsy; Chronic Disease; Gastric Mucosa; Gastritis; Gas

1971
Self-poisoning. II.
    British medical journal, 1965, Dec-04, Volume: 2, Issue:5474

    Topics: Adolescent; Adult; Aged; Alcoholism; Aspirin; Behavior; Drug Prescriptions; Humans; Middle Aged; Mot

1965
Attempted suicide in Durban: a general hospital study.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, Jan-29, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Alcoholism; Antisocial Personality Disorder; Aspirin; Barbiturates; Black o

1966