Page last updated: 2024-10-22

aspirin and Albuminuria

aspirin has been researched along with Albuminuria in 25 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"To assess the effect of aspirin use in low-risk pregnancy on: (1) pregnancy-associated plasma protein-A (PAPP-A) and placental-like growth factor (PLGF); (2) urinary albumin-to-creatinine ratio (ACR) and blood pressure; (3) fetal growth parameters; and (4) placental histopathology."9.30Evaluation of the Effect of Low-Dose Aspirin on Biochemical and Biophysical Biomarkers for Placental Disease in Low-Risk Pregnancy: Secondary Analysis of a Multicenter RCT. ( Clarke, P; Culliton, M; Downey, P; Fitzgerald, D; Maguire, OC; Malone, FD; McAuliffe, FM; McParland, P; Mone, F; Mooney, EE; Mulcahy, C; Tully, E, 2019)
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."9.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
" Following a three week course of aspirin (330 mg)--dipyridamole (75 mg) taken three times daily there was significant reduction in exercise-induced albuminuria (expressed as the ratio of albumin excretion rate during exercise to that at rest before exercise) when compared to administration of placebo (P less than 0."9.06Reduction of exercise-induced albuminuria by aspirin-dipyridamole in patients with diabetes mellitus. ( Davies, JA; Hopper, AH; Tindall, H; Urquhart, S, 1987)
"To assess the effect of aspirin use in low-risk pregnancy on: (1) pregnancy-associated plasma protein-A (PAPP-A) and placental-like growth factor (PLGF); (2) urinary albumin-to-creatinine ratio (ACR) and blood pressure; (3) fetal growth parameters; and (4) placental histopathology."5.30Evaluation of the Effect of Low-Dose Aspirin on Biochemical and Biophysical Biomarkers for Placental Disease in Low-Risk Pregnancy: Secondary Analysis of a Multicenter RCT. ( Clarke, P; Culliton, M; Downey, P; Fitzgerald, D; Maguire, OC; Malone, FD; McAuliffe, FM; McParland, P; Mone, F; Mooney, EE; Mulcahy, C; Tully, E, 2019)
"Forty patients who had diabetes with nephropathy and arteriosclerosis obliterans and had already been treated with angiotensin II receptor blocker (n = 40) were randomly assigned to sarpogrelate (300 mg/d; n = 20) or aspirin group (100 mg/d; n = 20)."5.13Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes. ( Ishizuka, T; Ito, S; Mori, T; Nako, K; Ogawa, S, 2008)
" Following a three week course of aspirin (330 mg)--dipyridamole (75 mg) taken three times daily there was significant reduction in exercise-induced albuminuria (expressed as the ratio of albumin excretion rate during exercise to that at rest before exercise) when compared to administration of placebo (P less than 0."5.06Reduction of exercise-induced albuminuria by aspirin-dipyridamole in patients with diabetes mellitus. ( Davies, JA; Hopper, AH; Tindall, H; Urquhart, S, 1987)
"Previous studies have demonstrated that urinary thromboxane B2 (TXB2) excretion (UTXB2) and glomerular production of TXB2 are enhanced in experimental diabetes and that selective inhibitors of TX synthesis prevent or delay the development of albuminuria."3.68Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat. ( Craven, PA; DeRubertis, FR, 1992)
"Low-dose Aspirin inhibits thromboxane A2 with minimal effects on prostacyclin and induces clinical improvements in pre-eclampsia."3.68Treatment of severe pre-eclampsia by acetyl salicylic acid. ( Abd-Rabbo, S; Khowessah, M; Shaala, S; Toppozada, M; Zoheir, A, 1991)
"Careful counseling of women with diabetic nephropathy before pregnancy with estimation of the risk for the mother and fetus is important."2.48Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment. ( Clausen, P; Damm, P; Feldt-Rasmussen, B; Mathiesen, ER; Ringholm, L, 2012)
"Therefore, prevention and treatment of diabetic nephropathy has become a prominent goal in the treatment of patients with diabetes mellitus."2.42Prevention and treatment of diabetic nephropathy in older patients. ( Jungmann, E, 2003)
"Aspirin was used in 64% of patients with CAD and in 28."1.35Control of cardiovascular risk factors and use of aspirin in diabetic patients remain elusive. ( Garg, P; Jeevanantham, V; Khan, A; Nautiyal, A; Reddy, PC; Shrivastava, R, 2008)
"But aspirin therapy was used in only 35 cases (32."1.33The rate of checking urine microalbumin and aspirin primary prevention in type 2 DM. ( Limpawattana, P; Mahankkanukrauh, A; Sawanyawisuth, K; Wongvipaporn, C, 2006)
"Aspirin was used regularly by 37% of those with CVD and by 13% of those with risk factors only Adjusted odds of regular aspirin use were significantly greater for individuals with CVD than for those with one CVD risk factor (odds ratio [OR] = 4."1.31Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey. ( Fagot-Campagna, A; Narayan, KM; Rolka, DB, 2001)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.00)18.7374
1990's5 (20.00)18.2507
2000's10 (40.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Walker, RG1
Wolfe, R1
Bongetti, E1
Polkinghorne, KR1
Woods, RL1
Ryan, J1
Espinoza, S1
Murray, A1
Ernst, ME1
Mcneil, JJ1
Ma, KL1
Liu, L1
Zhang, Y1
Wang, GH1
Hu, ZB1
Chen, PP1
Lu, J1
Lu, CC1
Gong, TK1
Gong, YX1
Liu, BC1
Mone, F1
Mulcahy, C1
McParland, P1
Downey, P1
Culliton, M1
Maguire, OC1
Mooney, EE1
Clarke, P1
Fitzgerald, D1
Tully, E1
Malone, FD1
McAuliffe, FM1
Zaccardi, F1
Rizzi, A1
Petrucci, G1
Ciaffardini, F1
Tanese, L1
Pagliaccia, F1
Cavalca, V1
Ciminello, A1
Habib, A1
Squellerio, I1
Rizzo, P1
Tremoli, E1
Rocca, B1
Pitocco, D1
Patrono, C1
Yassine, HN1
Davis-Gorman, G1
Stump, CS1
Thomson, SS1
Peterson, J1
McDonagh, PF1
Crasto, W1
Jarvis, J1
Khunti, K1
Skinner, TC1
Gray, LJ1
Brela, J1
Troughton, J1
Daly, H1
Lawrence, IG1
McNally, PG1
Carey, ME1
Davies, MJ1
Mathiesen, ER1
Ringholm, L1
Feldt-Rasmussen, B1
Clausen, P1
Damm, P1
Gaede, P1
Hansen, HP2
Parving, HH2
Pedersen, O1
Jungmann, E1
Sawanyawisuth, K1
Limpawattana, P1
Mahankkanukrauh, A1
Wongvipaporn, C1
Garcia-Donaire, JA1
Ruilope, LM1
Thomas, MC1
Ogawa, S1
Mori, T1
Nako, K1
Ishizuka, T1
Ito, S1
Agodoa, LY1
Francis, ME1
Eggers, PW1
Shrivastava, R1
Khan, A1
Jeevanantham, V1
Nautiyal, A1
Garg, P1
Reddy, PC1
Watanabe, Y1
Suzui, J1
Ichikawa, Y1
Yoshida, K1
Suzuki, H1
Faas, MM1
Schuiling, GA1
Baller, JF1
Valkhof, N1
Bakker, WW1
Gaede, PH1
Jensen, BR1
Rolka, DB1
Fagot-Campagna, A1
Narayan, KM1
DeRubertis, FR1
Craven, PA1
Toppozada, M2
Darwish, EA1
Osman, YF1
Abd-Rabbo, MS1
Khowessah, M1
Shaala, S1
Abd-Rabbo, S1
Zoheir, A1
Hopper, AH1
Tindall, H1
Urquhart, S1
Davies, JA1
Husted, SE1
Nielsen, HK1
Petersen, T1
Mogensen, CE1
Geday, E1
Chalmers, TM1

Reviews

3 reviews available for aspirin and Albuminuria

ArticleYear
Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:12

    Topics: Albuminuria; Antihypertensive Agents; Aspirin; Counseling; Diabetes Mellitus, Type 1; Diabetes Melli

2012
Prevention and treatment of diabetic nephropathy in older patients.
    Drugs & aging, 2003, Volume: 20, Issue:6

    Topics: Aged; Albuminuria; Antihypertensive Agents; Aspirin; Blood Glucose; Clinical Trials as Topic; Diabet

2003
Spotlight on renin: cardiovascular outcomes in chronic kidney disease and suppression of the renin-angiotensin system.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2006, Volume: 7, Issue:1

    Topics: Albuminuria; Aspirin; Cardiovascular Diseases; Chronic Disease; Glomerular Filtration Rate; Humans;

2006

Trials

8 trials available for aspirin and Albuminuria

ArticleYear
Evaluation of the Effect of Low-Dose Aspirin on Biochemical and Biophysical Biomarkers for Placental Disease in Low-Risk Pregnancy: Secondary Analysis of a Multicenter RCT.
    American journal of perinatology, 2019, Volume: 36, Issue:13

    Topics: Adult; Albuminuria; Aspirin; Biomarkers; Creatinine; Female; Fetal Development; Humans; Placenta; Pl

2019
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: the Microalbuminuria Education and Medication Optimisation (MEMO) study.
    Diabetes research and clinical practice, 2011, Volume: 93, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Antihypertensive Agents; Aspirin; Blood Pressure; Chole

2011
Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:3

    Topics: Adult; Aged; Albuminuria; Aspirin; Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus, T

2003
Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:2

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis Obliterans; Aspirin; Ch

2008
Lack of impact of low-dose acetylsalicylic acid on kidney function in type 1 diabetic patients with microalbuminuria.
    Diabetes care, 2000, Volume: 23, Issue:12

    Topics: Adult; Albuminuria; Aspirin; Blood Pressure; Chromatography, High Pressure Liquid; Cross-Over Studie

2000
Low dose acetyl salicylic acid in severe preeclampsia.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1991, Volume: 35, Issue:4

    Topics: Albuminuria; Aspirin; Blood Pressure; Edema; Female; Humans; Pre-Eclampsia; Pregnancy

1991
Reduction of exercise-induced albuminuria by aspirin-dipyridamole in patients with diabetes mellitus.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:5

    Topics: Adult; Albuminuria; Aspirin; Diabetes Mellitus, Type 1; Dipyridamole; Drug Therapy, Combination; Hum

1987
Clinical experience with Ibuprofen in the treatment of rheumatoid arthritis.
    Annals of the rheumatic diseases, 1969, Volume: 28, Issue:5

    Topics: Albuminuria; Alkaline Phosphatase; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspa

1969

Other Studies

14 other studies available for aspirin and Albuminuria

ArticleYear
The association of frailty with chronic kidney disease in older adults using the ASPirin in reducing events in the elderly cohort.
    Nephrology (Carlton, Vic.), 2023, Volume: 28, Issue:1

    Topics: Aged; Albuminuria; Aspirin; Cross-Sectional Studies; Frailty; Glomerular Filtration Rate; Humans; Re

2023
Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway.
    International urology and nephrology, 2019, Volume: 51, Issue:3

    Topics: Albuminuria; Animals; Aspirin; Creatinine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines;

2019
In Vivo Platelet Activation and Aspirin Responsiveness in Type 1 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:2

    Topics: Adult; Albuminuria; Aspirin; Blood Glucose; Cross-Sectional Studies; Cyclooxygenase 1; Diabetes Mell

2016
Clinical determinants of aspirin resistance in diabetes.
    Diabetes research and clinical practice, 2010, Volume: 90, Issue:1

    Topics: Albuminuria; Aspirin; Cohort Studies; Diabetic Angiopathies; Drug Resistance; Female; Glycated Hemog

2010
The rate of checking urine microalbumin and aspirin primary prevention in type 2 DM.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:5

    Topics: Albuminuria; Aspirin; Atherosclerosis; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Humans; Hyp

2006
The assessment and management of albuminuria in primary care.
    Diabetes research and clinical practice, 2008, Volume: 80, Issue:1

    Topics: Aged; Albuminuria; Aspirin; Blood Glucose; Cardiovascular Diseases; Chronic Disease; Diabetes Mellit

2008
Association of analgesic use with prevalence of albuminuria and reduced GFR in US adults.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 51, Issue:4

    Topics: Acetaminophen; Adult; Aged; Albuminuria; Analgesics; Aspirin; Cross-Sectional Studies; Female; Glome

2008
Control of cardiovascular risk factors and use of aspirin in diabetic patients remain elusive.
    Southern medical journal, 2008, Volume: 101, Issue:6

    Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Albuminuria; Aspirin; Blood Pressure; Chol

2008
[The effect of peripheral blood mononuclear cell products from children with nephrotic syndrome on thromboxane A2 metabolism].
    Arerugi = [Allergy], 1995, Volume: 44, Issue:5

    Topics: Albuminuria; Animals; Aspirin; Blood Platelets; Cells, Cultured; Child; Female; Humans; Kidney Glome

1995
Aspirin treatment of the low-dose-endotoxin-treated pregnant rat: pathophysiologic and immunohistologic aspects.
    The Journal of laboratory and clinical medicine, 1997, Volume: 130, Issue:5

    Topics: Albuminuria; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apyrase; Aspirin; Blood Pressure; Cel

1997
Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey.
    Diabetes care, 2001, Volume: 24, Issue:2

    Topics: Adult; Albuminuria; Angina Pectoris; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabe

2001
Contribution of platelet thromboxane production to enhanced urinary excretion and glomerular production of thromboxane and to the pathogenesis of albuminuria in the streptozotocin-diabetic rat.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:1

    Topics: Albuminuria; Animals; Aspirin; Blood Platelets; Diabetes Mellitus, Experimental; Dinoprostone; Femal

1992
Treatment of severe pre-eclampsia by acetyl salicylic acid.
    Asia-Oceania journal of obstetrics and gynaecology, 1991, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Albuminuria; Aspirin; Blood Pressure; Body Temperature; Edema; Female; Humans; Hy

1991
Acute effects of acetylsalicylic acid on renal and hepatic function in normal humans.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Alanine Transaminase; Albuminuria; Aspartate Aminotransferases; Aspirin; beta 2-M

1985