aspirin has been researched along with Airway Obstruction in 25 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 9.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
| "The findings indicate that ongoing leukotriene production may be one cause of persistent airway obstruction in aspirin sensitive asthmatic subjects and that they may benefit from treatment with a leukotriene receptor antagonist." | 9.07 | Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. ( Dahlén, B; Dahlén, SE; Margolskee, DJ; Zetterström, O, 1993) |
| "We sought to investigate the role of aspirin-exacerbated respiratory disease (AERD) as a risk factor for the development of irreversible airway obstruction." | 7.73 | Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma. ( Bleecker, ER; Borish, L; Deniz, YM; Haselkorn, T; Mascia, K; Miller, DP, 2005) |
| "Nine patients with aspirin-induced bronchospasm were compared with age-matched normal controls to test the hypothesis that a defect in the beta-adrenergic system could lead to excessive dependence on prostaglandins to maintain bronchodilator function." | 7.66 | A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm. ( Conolly, ME; Fisher, HK; Hui, KK; Tashkin, DP; Wolfe, RN, 1982) |
| " Morning baseline values of urinary 9 alpha, 11 beta-PGF2 were measured in three groups--healthy volunteers (n = 9), patients with atopic asthma (n = 14), and aspirin-intolerant patients with asthma (n = 12)--and found to be very similar, 54 +/- 9, 62 +/- 6, and 71 +/- 15 ng/mmol creatinine, respectively (means +/- SEM)." | 5.08 | Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. ( Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S, 1996) |
| "The findings indicate that ongoing leukotriene production may be one cause of persistent airway obstruction in aspirin sensitive asthmatic subjects and that they may benefit from treatment with a leukotriene receptor antagonist." | 5.07 | Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. ( Dahlén, B; Dahlén, SE; Margolskee, DJ; Zetterström, O, 1993) |
| "First described as a component of a triad seen among adults with nonallergic asthma and nasal polyps, aspirin sensitivity has subsequently been documented as a frequent concomitant of a wide range of patients with chronic asthma." | 5.04 | Analgesic sensitivity in children with asthma. ( Weinberger, M, 1978) |
| "We sought to investigate the role of aspirin-exacerbated respiratory disease (AERD) as a risk factor for the development of irreversible airway obstruction." | 3.73 | Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma. ( Bleecker, ER; Borish, L; Deniz, YM; Haselkorn, T; Mascia, K; Miller, DP, 2005) |
| "The Fernand Widal syndrome combines a nasal polyposis, an asthma and aspirin sensitivity." | 3.70 | [Fernand Widal syndrome: apropos of 2 cases]. ( Ba, O; Cissokho, S; Dia, Y; Diatta, A; Diouf, R; Hane, AA; Kandji, M; Ndiaye, M; Ndiaye, S; Ndir, M; Niang, A, 1999) |
| "Nine patients with aspirin-induced bronchospasm were compared with age-matched normal controls to test the hypothesis that a defect in the beta-adrenergic system could lead to excessive dependence on prostaglandins to maintain bronchodilator function." | 3.66 | A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm. ( Conolly, ME; Fisher, HK; Hui, KK; Tashkin, DP; Wolfe, RN, 1982) |
| "The patient was treated for presumptive peritonsillar abscess." | 1.48 | Acute peritonsillar swelling: a unique presentation for Kawasaki disease in adolescence. ( Connell, JT; Park, JH, 2018) |
| "We present a case of acute upper airway obstruction secondary to angio-oedema." | 1.34 | Emergency percutaneous tracheostomy. ( Jonas, N; Joubert, J; Mulwafu, W, 2007) |
| " Neither differences in bioavailability of ASA nor the formation of SA seems to contribute to the aspirin-elicited reactions." | 1.29 | Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects. ( Anderson, P; Andersson, R; Boréus, LO; Dahlén, B; Zetterström, O, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (64.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connell, JT | 1 |
| Park, JH | 1 |
| Cahill, KN | 1 |
| Murphy, K | 1 |
| Singer, J | 1 |
| Israel, E | 1 |
| Boyce, JA | 1 |
| Laidlaw, TM | 1 |
| Mascia, K | 1 |
| Haselkorn, T | 1 |
| Deniz, YM | 1 |
| Miller, DP | 1 |
| Bleecker, ER | 1 |
| Borish, L | 1 |
| Jonas, N | 1 |
| Mulwafu, W | 1 |
| Joubert, J | 1 |
| Wolfe, RN | 1 |
| Hui, KK | 1 |
| Conolly, ME | 1 |
| Tashkin, DP | 1 |
| Fisher, HK | 1 |
| Herzog, H | 1 |
| Weiss, JW | 1 |
| Drazen, JM | 1 |
| McFadden, ER | 1 |
| Weller, P | 1 |
| Corey, EJ | 1 |
| Lewis, RA | 1 |
| Austen, KF | 1 |
| Andersen, PE | 1 |
| Heslet, L | 1 |
| Elle, B | 1 |
| Bastholt, L | 1 |
| Small, P | 1 |
| Frenkiel, S | 1 |
| Black, M | 1 |
| Szczeklik, A | 1 |
| Gryglewski, RJ | 1 |
| Czerniawska-Mysik, G | 1 |
| Nizankowska, E | 1 |
| Dahlén, B | 4 |
| Boréus, LO | 1 |
| Anderson, P | 1 |
| Andersson, R | 1 |
| Zetterström, O | 2 |
| Margolskee, DJ | 1 |
| Dahlén, SE | 3 |
| O'Sullivan, S | 1 |
| Kumlin, M | 1 |
| Ndiaye, M | 1 |
| Hane, AA | 1 |
| Ndir, M | 1 |
| Ba, O | 1 |
| Cissokho, S | 1 |
| Kandji, M | 1 |
| Ndiaye, S | 1 |
| Diatta, A | 1 |
| Niang, A | 1 |
| Dia, Y | 1 |
| Diouf, R | 1 |
| Weinberger, M | 1 |
| Ialkut, SI | 1 |
| Petrovskaia, IA | 1 |
| Evseeva, TA | 1 |
| Danilova, SA | 1 |
| Dekhtiarenko, SP | 1 |
| Partridge, MR | 1 |
| Gibson, GJ | 1 |
| Basomba, A | 1 |
| Romar, A | 1 |
| Peláez, A | 1 |
| Villalmanzo, IG | 1 |
| Campos, A | 1 |
| Jacobs, JC | 1 |
| Hui, RM | 1 |
| Stenius, BS | 1 |
| Lemola, M | 1 |
| Delaney, JC | 1 |
| Reed, CE | 1 |
| Rosenthale, ME | 1 |
| Begany, AJ | 1 |
| Dervinis, A | 1 |
| Malis, JL | 1 |
| Shriver, DA | 1 |
| Datko, SL | 1 |
| Gluckman, MI | 1 |
| Hyde, JS | 1 |
| Floro, LD | 1 |
| Vithayasai, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Laryngeal Manifestations of Connective Tissue Diseases[NCT04582292] | 50 participants (Anticipated) | Observational [Patient Registry] | 2020-11-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aspirin and Airway Obstruction
| Article | Year |
|---|---|
Pathophysiological basis of asthma management.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Bro | 1981 |
Leukotrienes as mediators of airway obstruction and inflammation in asthma.
Topics: Airway Obstruction; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid | 1995 |
4 trials available for aspirin and Airway Obstruction
| Article | Year |
|---|---|
Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects.
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Bronchi; Double-Blind Method; Female; Forced Expiratory | 1993 |
Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction.
Topics: Adult; Airway Obstruction; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Chromatography, | 1996 |
Analgesic sensitivity in children with asthma.
Topics: Acetaminophen; Adolescent; Airway Obstruction; Analgesics; Aspirin; Asthma; Child; Clinical Trials a | 1978 |
Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma.
Topics: Adolescent; Adult; Aged; Aging; Airway Obstruction; Aspirin; Asthma; Azo Compounds; Benzenesulfonate | 1976 |
19 other studies available for aspirin and Airway Obstruction
| Article | Year |
|---|---|
Acute peritonsillar swelling: a unique presentation for Kawasaki disease in adolescence.
Topics: Adolescent; Airway Obstruction; Aspirin; Diagnosis, Differential; Drug Therapy, Combination; Edema; | 2018 |
Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease.
Topics: Acetates; Administration, Oral; Adult; Airway Obstruction; Allergens; Anti-Asthmatic Agents; Aspirin | 2019 |
Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma.
Topics: Adolescent; Adult; Airway Obstruction; Anti-Asthmatic Agents; Aspirin; Asthma; Case-Control Studies; | 2005 |
Emergency percutaneous tracheostomy.
Topics: Aged; Airway Obstruction; Angioedema; Aspirin; Emergency Service, Hospital; Emergency Treatment; Fat | 2007 |
A study of beta-adrenergic and prostaglandin receptors in patients with aspirin-induced bronchospasm.
Topics: Adult; Aged; Airway Obstruction; Alprostadil; Aspirin; Bronchial Spasm; Female; Forced Expiratory Vo | 1982 |
Airway constriction in normal humans produced by inhalation of leukotriene D. Potency, time course, and effect of aspirin therapy.
Topics: Adult; Aerosols; Airway Obstruction; Aspirin; Bronchi; Constriction, Pathologic; Dose-Response Relat | 1983 |
Pulmonary airflow obstruction following lymphography.
Topics: Adult; Aged; Airway Obstruction; Aspirin; Female; Forced Expiratory Volume; Humans; Lymphography; Ma | 1982 |
Multifactorial etiology of nasal polyps.
Topics: Airway Obstruction; Antigen-Antibody Complex; Aspirin; Complement System Proteins; Humans; Immunoglo | 1981 |
Aspirin, prostaglandins, and bronchial asthma.
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Female; Humans; Male; Middle Aged; Prostaglandins | 1980 |
Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects.
Topics: Administration, Oral; Adult; Airway Obstruction; Aspirin; Asthma; Bronchial Provocation Tests; Femal | 1994 |
[Fernand Widal syndrome: apropos of 2 cases].
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Cyclooxygenase Inhibitors; Female; Headache; Humans; Hyp | 1999 |
[Study of the characteristics of pathogenesis and clinical course of asthmatic triad].
Topics: Adult; Airway Obstruction; Aspirin; Asthma; Diagnosis, Differential; Drug Hypersensitivity; Female; | 1979 |
Adverse bronchial reactions to intravenous hydrocortisone in two aspirin-sensitive asthmatic patients.
Topics: Adult; Aged; Airway Obstruction; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Hydrocortis | 1978 |
The effect of sodium cromoglycate in preventing aspirin induced bronchospasm.
Topics: Adult; Airway Obstruction; Aspirin; Bronchial Spasm; Cromolyn Sodium; Drug Evaluation; Drug Hypersen | 1976 |
Cricoarytenoid arthritis and airway obstruction in juvenile rheumatoid arthritis.
Topics: Airway Obstruction; Arthritis, Juvenile; Aspirin; Child, Preschool; Dexamethasone; Humans; Laryngeal | 1977 |
The diagnosis of aspirin idiosyncrasy by analgesic challenge.
Topics: Acetaminophen; Adolescent; Adult; Aged; Airway Obstruction; Aspirin; Asthma; Drug Hypersensitivity; | 1976 |
New therapeutic approaches in asthma.
Topics: Adrenergic beta-Agonists; Aerosols; Airway Obstruction; Aspirin; Asthma; Bronchi; Bronchodilator Age | 1986 |
Anti-inflammatory properties of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin).
Topics: Airway Obstruction; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; B | 1974 |
Chronic and high risk asthma in children.
Topics: Adolescent; Adrenal Cortex Hormones; Aerosols; Airway Obstruction; Aspergillosis; Aspirin; Asthma; B | 1972 |