Page last updated: 2024-10-23

aspirin and Airway Hyper-Responsiveness

aspirin has been researched along with Airway Hyper-Responsiveness in 56 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"This review is set to revisit the pathogenesis of aspirin-exacerbated respiratory disease (AERD), the diagnostic method used, and finally the real impact of aspirin desensitization on chronic sinusitis with nasal polyposis (CRSwNP) in aspirin intolerant patients."8.87Role of aspirin desensitization in the management of chronic rhinosinusitis. ( Rizk, H, 2011)
"Aspirin-exacerbated respiratory disease (AERD) is a chronic inflammatory disease characterized by chronic rhinosinusitis, nasal polyposis, asthma, and airway reactivity to aspirin and other nonsteroidal antiinflammatory drugs (NSAIDs)."8.84The clinical effectiveness of aspirin desensitization in chronic rhinosinusitis. ( Williams, AN; Woessner, KM, 2008)
" Aspirin-exacerbated respiratory disease (AERD) is defined as asthma, chronic rhinosinusitis with nasal polyposis, and hypersensitivity to cyclooxygenase-1 inhibitors."7.85Immunoglobulin G4 sinusitis in association with aspirin-exacerbated respiratory disease. ( Johal, K; Peters, A; Welch, K, 2017)
"Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks."7.74Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008)
"This study confirms the importance of eosinophil infiltration in the pathogenesis of severe or recurrent nasal polyps based on allergy and aspirin intolerance."7.70[Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa]. ( Bittinger, F; Gosepath, J; Kaldenbach, T; Klimek, L; Mann, WJ; Schäfer, D, 1999)
"The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease."7.70[Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000)
"Aspirin-exacerbated respiratory disease (AERD) is characterized by progressive sinusitis, nasal polyposis, and asthma that begins and continues in the absence of exposure to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs)."5.11Safety of high-dose rofecoxib in patients with aspirin-exacerbated respiratory disease. ( Simon, RA; Stevenson, DD; Woessner, KM, 2004)
"This review is set to revisit the pathogenesis of aspirin-exacerbated respiratory disease (AERD), the diagnostic method used, and finally the real impact of aspirin desensitization on chronic sinusitis with nasal polyposis (CRSwNP) in aspirin intolerant patients."4.87Role of aspirin desensitization in the management of chronic rhinosinusitis. ( Rizk, H, 2011)
"Aspirin-exacerbated respiratory disease (AERD) is a chronic inflammatory disease characterized by chronic rhinosinusitis, nasal polyposis, asthma, and airway reactivity to aspirin and other nonsteroidal antiinflammatory drugs (NSAIDs)."4.84The clinical effectiveness of aspirin desensitization in chronic rhinosinusitis. ( Williams, AN; Woessner, KM, 2008)
"Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis, nasal polyposis, asthma and precipitation of asthma, and rhinitis attacks after ingestion of aspirin (ASA) and most other nonsteroidal antiinflammatory drugs (NSAIDs)."4.82Natural history and clinical features of aspirin-exacerbated respiratory disease. ( Fahrenholz, JM, 2003)
"Aspirin-exacerbated respiratory disease (AERD) is an adult-onset condition that manifests as asthma, rhinosinusitis/nasal polyps, and sensitivity to aspirin and other cyclooxygenase-1 (COX-1)-inhibitor nonsteroidal anti-inflammatory drugs (NSAIDs)."4.82Adverse respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs. ( Simon, RA, 2004)
"Relevant articles in the medical literature were derived from searching the MEDLINE database with key terms aspirin-sensitive asthma, cyclo-oxygenase enzymes 1 and 2."4.81Sensitivity to nonsteroidal anti-inflammatory drugs. ( Namazy, JA; Simon, RA, 2002)
" Aspirin-exacerbated respiratory disease (AERD) is defined as asthma, chronic rhinosinusitis with nasal polyposis, and hypersensitivity to cyclooxygenase-1 inhibitors."3.85Immunoglobulin G4 sinusitis in association with aspirin-exacerbated respiratory disease. ( Johal, K; Peters, A; Welch, K, 2017)
"Multiple NSAID-induced urticaria/angioedema (MNSAID-UA) is an entity well differentiated from aspirin-exacerbated respiratory disease (AERD), although no detailed phenotype analysis has yet been performed."3.79Mediator release after nasal aspirin provocation supports different phenotypes in subjects with hypersensitivity reactions to NSAIDs. ( Ayuso, P; Blanca, M; Blanca-López, N; Campo, P; Canto, G; Cornejo-García, JA; Doña, I; Guéant, JL; Plaza, MC; Salas, M; Sanak, M; Torres, MJ, 2013)
"Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome associated with chronic inflammation in the airways coincident with chronic rhinitis, sinusitis, recurrent polyposis and asthma."3.78Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease. ( Jin, HJ; Kim, SH; Park, HS; Song, YS; Yang, EM, 2012)
"Without prior exposure to aspirin or NSAIDs, the chance of a positive OAC was 5 in 12 (42%) but was 198 in 231 (86%) for those with a history of aspirin- and NSAID-associated asthma attacks."3.74Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. ( Dursun, AB; Karasoy, D; Simon, RA; Stevenson, DD; Woessner, KA, 2008)
" Often it is associated with non allergic rhinitis with eosinophilia syndrome (NARES), nasal polyposis and intolerance to Aspirin and NSAID's."3.74[Nonallergic diseases of the upper and lower airways]. ( Menz, G; Rothe, T, 2008)
"This study confirms the importance of eosinophil infiltration in the pathogenesis of severe or recurrent nasal polyps based on allergy and aspirin intolerance."3.70[Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa]. ( Bittinger, F; Gosepath, J; Kaldenbach, T; Klimek, L; Mann, WJ; Schäfer, D, 1999)
"The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease."3.70[Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000)
"The following beliefs about aspirin sensitivity are widely held: (1) it usually is accompanied by nasal polyps."3.65Aspirin allergy: a clinical study. ( Speer, F, 1975)
"Aspirin-like drugs inhibit the biosynthesis of prostaglandins in all tissues and species so far studied."2.35The mode of action of aspirin and similar compounds. ( Vane, JR, 1976)
"Misoprostol (200 μg) was administered at 30 minutes, 90 minutes, and 4 hours after the first dose of nasal ketorolac."1.46Effect of misoprostol on patients with aspirin-exacerbated respiratory disease undergoing aspirin challenge and desensitization. ( Simon, RA; Walters, KM; White, AA; Wineinger, NE; Woessner, KM, 2017)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199015 (26.79)18.7374
1990's8 (14.29)18.2507
2000's23 (41.07)29.6817
2010's10 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cook, KA1
Modena, BD1
Wineinger, NE2
Woessner, KM5
Simon, RA8
White, AA3
Walters, KM1
Johal, K1
Welch, K1
Peters, A1
Fruth, K1
Pogorzelski, B1
Schmidtmann, I1
Springer, J1
Fennan, N1
Fraessdorf, N1
Boessert, A1
Schaefer, D1
Gosepath, J2
Mann, WJ2
Campo, P1
Ayuso, P1
Salas, M1
Plaza, MC1
Cornejo-García, JA1
Doña, I1
Torres, MJ1
Blanca-López, N1
Canto, G1
Guéant, JL1
Sanak, M1
Blanca, M1
Baudrand, H1
Zaouche, S1
Dubost, R1
Carsin, A1
Chatte, G1
Freymond, N1
Piperno, D1
Dubreuil, C1
Froehlich, P1
Pacheco, Y1
Devouassoux, G1
Teran, LM1
Ramirez-Jimenez, F1
Soid-Raggi, G1
Velazquez, JR1
Dursun, AB1
Woessner, KA1
Karasoy, D1
Stevenson, DD5
Rothe, T1
Menz, G1
Williams, AN1
Das, S1
Maeso, PA1
Becker, AM1
Prosser, JD1
Adam, BL1
Kountakis, SE1
Taniguchi, M1
Okano, M1
Rizk, H1
Song, YS1
Yang, EM1
Kim, SH1
Jin, HJ1
Park, HS1
Namazy, JA1
Fahrenholz, JM1
Zuraw, BL1
VIGUIE, R1
GARDIES, AL1
Solensky, R1
Ramanuja, S1
Breall, JA1
Kalaria, VG1
Shah, A1
Panjabi, C1
Semik, A1
Barczyk, A1
Pierzchała, W1
Smith, WB1
Wormald, PJ1
Cohn, JR1
Farooque, S1
Lee, TH1
Buisseret, PD1
VanArsdel, PP1
McFadden, ER1
Busse, WW1
Hassoun, S1
Bonneau, JC1
Drouet, M1
Sabbah, A1
Sainte-Laudy, J2
Vallon, C2
Guérin, JC2
Blanco, C1
Quiralte, J1
Castillo, R1
Delgado, J1
Arteaga, C1
Barber, D1
Carrillo, T1
Matsuse, H1
Shimoda, T1
Matsuo, N1
Fukushima, C1
Takao, A1
Sakai, H1
Asai, S1
Kohno, S1
Kaldenbach, T1
Schäfer, D1
Bittinger, F1
Klimek, L1
May, A1
Wagner, D1
Langenbeck, U1
Weber, A1
Udovicki, J1
Milakov, J1
Damnjanović-Cokić, J1
Poljacki, M1
Vane, JR1
Speer, F1
Vincent, D1
Lefort, J1
Bureau, M1
Dry, J1
Vargaftig, BB1
Manning, ME1
Jankowski, R1
Béné, MC1
Moneret-Vautrin, AD1
Haas, F1
Faure, G1
Simon, C1
Wayoff, M1
Cooper, JA1
Matthay, RA1
Fisherman, EW1
Cohen, GN1
Fein, BT1
Caplin, I1
Haynes, JT1
Spahn, J1
Miller, FF1
Girard, JP1
Hildebrandt, F1
Favre, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dupilumab as add-on Therapy for Aspirin-exacerbated Respiratory Disease (AERD)[NCT03595488]Phase 211 participants (Actual)Interventional2018-09-05Completed
Improving Patient Care Via Proteomics Based, Microbe-Specific Detection of Chronic Rhinosinusitis[NCT00962689]38 participants (Actual)Observational2009-08-31Completed
Double Blind Study to Determine Effect of Omalizumab Treatment in Patients With the Co-Morbid Conditions of Aspirin Exacerbated Respiratory Disease(AERD) and Allergic Asthma and Rhinitis.[NCT00286416]60 participants Interventional2006-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for aspirin and Airway Hyper-Responsiveness

ArticleYear
The clinical effectiveness of aspirin desensitization in chronic rhinosinusitis.
    Current allergy and asthma reports, 2008, Volume: 8, Issue:3

    Topics: Administration, Oral; Aspirin; Chronic Disease; Desensitization, Immunologic; Humans; Lysine; Nasal

2008
Role of aspirin desensitization in the management of chronic rhinosinusitis.
    Current opinion in otolaryngology & head and neck surgery, 2011, Volume: 19, Issue:3

    Topics: Aspirin; Chronic Disease; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Nasal Polyps;

2011
Sensitivity to nonsteroidal anti-inflammatory drugs.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 89, Issue:6

    Topics: Acetaminophen; Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleedin

2002
Natural history and clinical features of aspirin-exacerbated respiratory disease.
    Clinical reviews in allergy & immunology, 2003, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Cross Reactio

2003
Crossreacting drugs and chemicals.
    Clinical reviews in allergy & immunology, 2003, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase 1; Cyclooxygenase

2003
Aspirin desensitization in patients with AERD.
    Clinical reviews in allergy & immunology, 2003, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Desensitization, Immunologic; Dose-Response Relati

2003
Prevention and treatment of reactions to NSAIDs.
    Clinical reviews in allergy & immunology, 2003, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Desens

2003
Pathogenesis of aspirin-exacerbated respiratory disease.
    Clinical reviews in allergy & immunology, 2003, Volume: 24, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2003
Adverse respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs.
    Current allergy and asthma reports, 2004, Volume: 4, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Desensit

2004
Treatment of patients with respiratory reactions to aspirin and nonsteroidal anti-inflammatory drugs.
    Current allergy and asthma reports, 2004, Volume: 4, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Diseas

2004
Drug allergy: desensitization and treatment of reactions to antibiotics and aspirin.
    Clinical allergy and immunology, 2004, Volume: 18

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dese

2004
Approach to "aspirin allergy" in cardiovascular patients.
    Circulation, 2004, Jul-06, Volume: 110, Issue:1

    Topics: Anaphylaxis; Aspirin; Coronary Artery Disease; Drug Hypersensitivity; Humans; Platelet Aggregation I

2004
[Provocation tests in the diagnosis of acetylsalicylic acid intolerance].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2005, Volume: 58, Issue:9-10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersen

2005
The mode of action of aspirin and similar compounds.
    The Journal of allergy and clinical immunology, 1976, Volume: 58, Issue:6

    Topics: Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Bronchi; Dermatitis, Atopic; Drug Hypersensiti

1976
Drug-induced pulmonary disease.
    Disease-a-month : DM, 1987, Volume: 33, Issue:2

    Topics: Anti-Arrhythmia Agents; Anticonvulsants; Antineoplastic Agents; Aspirin; Gold; Humans; Hydrochloroth

1987

Trials

2 trials available for aspirin and Airway Hyper-Responsiveness

ArticleYear
Low-dose aspirin desensitization in individuals with aspirin-exacerbated respiratory disease.
    Allergy, 2013, Volume: 68, Issue:5

    Topics: Adult; Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Female; Follow-Up Studies; Huma

2013
Safety of high-dose rofecoxib in patients with aspirin-exacerbated respiratory disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross Reactions; Cyclooxygenase Inhibitors

2004

Other Studies

39 other studies available for aspirin and Airway Hyper-Responsiveness

ArticleYear
Use of a composite symptom score during challenge in patients with suspected aspirin-exacerbated respiratory disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017, Volume: 118, Issue:5

    Topics: Adult; Aged; Aspirin; Drug Hypersensitivity; Female; Humans; Immunization; Immunoglobulin E; Male; M

2017
Effect of misoprostol on patients with aspirin-exacerbated respiratory disease undergoing aspirin challenge and desensitization.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017, Volume: 119, Issue:1

    Topics: Adolescent; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Desensit

2017
Immunoglobulin G4 sinusitis in association with aspirin-exacerbated respiratory disease.
    American journal of rhinology & allergy, 2017, Sep-01, Volume: 31, Issue:5

    Topics: Aspirin; Asthma, Aspirin-Induced; Humans; Immunoglobulin G; Male; Middle Aged; Nasal Polyps; Respira

2017
An update on the epidemiology of aspirin-exacerbated respiratory disease.
    American journal of rhinology & allergy, 2017, Sep-01, Volume: 31, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Humans; Nasal Polyps; Pre

2017
Mediator release after nasal aspirin provocation supports different phenotypes in subjects with hypersensitivity reactions to NSAIDs.
    Allergy, 2013, Volume: 68, Issue:8

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Stero

2013
[Aspirin hypersensitivity: characteristics and diagnostic approach].
    Revue des maladies respiratoires, 2015, Volume: 32, Issue:3

    Topics: Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Blood Cell Count; Blood Platelets; Comorbidity;

2015
Interleukin 16 and CCL17/thymus and activation-regulated chemokine in patients with aspirin-exacerbated respiratory disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017, Volume: 118, Issue:2

    Topics: Adult; Aspirin; Biomarkers; Chemokine CCL17; Drug Hypersensitivity; Eosinophils; Female; Humans; Imm

2017
Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 100, Issue:5

    Topics: Administration, Oral; Adult; Age Factors; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Exp

2008
[Nonallergic diseases of the upper and lower airways].
    Therapeutische Umschau. Revue therapeutique, 2008, Volume: 65, Issue:3

    Topics: Aspirin; Asthma; Bronchitis; Diagnosis, Differential; Drug Hypersensitivity; Eosinophilia; Humans; I

2008
Proteomics blood testing to distinguish chronic rhinosinusitis subtypes.
    The Laryngoscope, 2008, Volume: 118, Issue:12

    Topics: Aspirin; Asthma; Biomarkers; Chronic Disease; Diagnosis, Differential; Drug Hypersensitivity; Fungi;

2008
[Measurement of airway hyperresponsiveness and aspirin sensitivity].
    Arerugi = [Allergy], 2009, Volume: 58, Issue:2

    Topics: Aspirin; Humans; Respiratory Hypersensitivity

2009
[Aspirin intolerance--from the viewpoint of otorhinolaryngology].
    Nihon Jibiinkoka Gakkai kaiho, 2009, Volume: 112, Issue:9

    Topics: Aspirin; Humans; Respiratory Hypersensitivity

2009
Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease.
    International archives of allergy and immunology, 2012, Volume: 159, Issue:2

    Topics: Adult; Arachidonate 15-Lipoxygenase; Asian People; Aspirin; Asthma; Asthma, Aspirin-Induced; Base Se

2012
[IS ASPIRIN A DANGEROUS DRUG?].
    Clinique (Paris, France), 1963, Oct-31, Volume: 58

    Topics: Anemia; Anemia, Hypochromic; Angioedema; Anticoagulants; Aspirin; Asthma; Blood Coagulation Disorder

1963
Asthma, hypersensitivity, and coitus.
    American journal of respiratory and critical care medicine, 2004, Nov-15, Volume: 170, Issue:10

    Topics: Aspirin; Asthma; Coitus; Follow-Up Studies; Humans; Male; Middle Aged; Respiratory Hypersensitivity;

2004
Allergy and sinus disease.
    The Medical journal of Australia, 2006, Nov-20, Volume: 185, Issue:10

    Topics: Anti-Allergic Agents; Aspirin; Drug Hypersensitivity; Humans; Nasal Polyps; Respiratory Hypersensiti

2006
Aspirin challenge and desensitization for aspirin-exacerbated respiratory disease: a practice paper.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2007, Volume: 99, Issue:2

    Topics: Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Desensitization, Immunologic; Drug Hy

2007
Aspirin sensitivity and eicosanoids.
    Thorax, 2008, Volume: 63, Issue:1

    Topics: Aspirin; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Eicosanoids; Humans; Respiratory Hypersen

2008
Allergy.
    Scientific American, 1982, Volume: 247, Issue:2

    Topics: Animals; Antibody Formation; Arachidonic Acids; Aspirin; Autacoids; B-Lymphocytes; Cromolyn Sodium;

1982
Aspirin idiosyncracy and tolerance.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Desensitization, Immunologic; Drug Tolerance; Female; Huma

1984
Pathogenesis of asthma.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:4

    Topics: Adult; Air Pollution; Allergens; Animals; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchi; Bronch

1984
Clinical aspects of bronchial asthma.
    Comprehensive therapy, 1980, Volume: 6, Issue:4

    Topics: Aspirin; Asthma; Carbon Dioxide; Environmental Pollutants; Humans; Medical History Taking; Oxygen; P

1980
[Survey of pathologies caused by sulfites in allergology].
    Allergie et immunologie, 1994, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aspirin; Child; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Female; F

1994
[Importance of the leukotriene C4 liberation test for the diagnosis of drug allergy (preliminary results)].
    Allergie et immunologie, 1996, Volume: 28, Issue:2

    Topics: Adult; Allergens; Ampicillin; Animals; Aspirin; Basophil Degranulation Test; Basophils; Cats; Drug E

1996
Anaphylaxis after ingestion of wheat flour contaminated with mites.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Allergens; Anaphylaxis; Animals; Antibodies, Monoclonal; Antigens, Dermatophagoid

1997
Aspirin-induced asthma as a risk factor for asthma mortality.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1997, Volume: 34, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Br

1997
[Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa].
    Laryngo- rhino- otologie, 1999, Volume: 78, Issue:8

    Topics: Adult; Aged; Aspirin; Drug Hypersensitivity; Eosinophilia; Eosinophils; Female; Humans; Male; Middle

1999
[Family study of patients with aspirin intolerance and rhinosinusitis].
    HNO, 2000, Volume: 48, Issue:9

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation T

2000
[Nasal polyposis and allergy to aspirin].
    Medicinski pregled, 1979, Volume: 32, Issue:5-6

    Topics: Adolescent; Adult; Aged; Aspirin; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nasal Po

1979
Aspirin allergy: a clinical study.
    Southern medical journal, 1975, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Drug Hypersensitivity; Fema

1975
[A familial case of metabisulfite intolerance. Clinical and pharmacological study].
    Allergie et immunologie, 1992, Volume: 24, Issue:8

    Topics: Adult; Alcoholic Beverages; Aspirin; Basophil Degranulation Test; Drug Hypersensitivity; Female; Foo

1992
Dissociation between LPS-induced bronchial hyperreactivity and airway edema in the guinea-pig.
    Agents and actions, 1991, Volume: 34, Issue:1-2

    Topics: Animals; Aspirin; Azepines; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Escherichia coli; Guin

1991
Aspirin sensitivity. A distressing reaction that is now often treatable.
    Postgraduate medicine, 1991, Volume: 90, Issue:5

    Topics: Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Respiratory Hypersensitivity

1991
Immunohistological characteristics of nasal polyps. A comparison with healthy mucosa and chronic sinusitis.
    Rhinology. Supplement, 1989, Volume: 8

    Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Aspirin; Asthma; Complement System Proteins; Drug

1989
Cholinergic and adrenergic stimulation correlated with aspirin intolerance (hypersensitivity).
    Annals of allergy, 1974, Volume: 33, Issue:4

    Topics: Aspirin; Atropine; Blood Coagulation; Blood Coagulation Tests; Drug Hypersensitivity; Ergonovine; Hu

1974
Aspirin shock associated with asthma and nasal polyps.
    Annals of allergy, 1971, Volume: 29, Issue:11

    Topics: Adolescent; Adult; Aspirin; Asthma; Bronchial Spasm; Child; Child, Preschool; Drug Hypersensitivity;

1971
Are nasal polyps an allergic phenomenon?
    Annals of allergy, 1971, Volume: 29, Issue:12

    Topics: Aspirin; Asthma; Cystic Fibrosis; Dermatitis, Atopic; Drug Hypersensitivity; Female; Humans; Hyperse

1971
History of drug sensitivity in atopic persons.
    The Journal of allergy, 1967, Volume: 40, Issue:1

    Topics: Aspirin; Asthma; Drug Hypersensitivity; Health Surveys; Penicillins; Respiratory Hypersensitivity; S

1967
Hypersensitivity to aspirin: clinical and immunological studies.
    Helvetica medica acta, 1969, Volume: 35, Issue:2

    Topics: Aged; Angioedema; Aspirin; Drug Hypersensitivity; Hemagglutination Tests; Humans; Male; Respiratory

1969