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aspirin and Agranulocytosis

aspirin has been researched along with Agranulocytosis in 18 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
" The examples presented are ampicillin rash in infectious mononucleosis, Reye's syndrome and drug-induced agranulocytosis."3.67The combined effect of viruses and drugs in drug-induced diseases. ( Levy, M, 1984)
"Acetaminophen is an effective antipyretic and analgesic with few side effects that is toxic only in massive overdose."2.36Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983)
"Acquired agranulocytosis is a rare, life-threatening disorder."1.38Mast cell activation syndrome masquerading as agranulocytosis. ( Afrin, LB, 2012)
" An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary."1.26[Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980)
"Aminopyrine alone was responsible for eight cases."1.24Agranulocytosis: a report of 30 cases. ( Colpron, G; Gosselin, G; Long, LA; Pretty, HM, 1965)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afrin, LB1
LABRAM, C1
Gladtke, E1
Levy, M1
Obel, AO1
Ell, C1
Domschke, S1
Domschke, W1
Dahinden, C1
Fehr, J1
Stobbe, H1
Hüge, W1
Haushofer, A1
Halbmayer, WM1
Prachar, H1
Hoigné, R1
Sherman, WB1
Gracheva, NM1
Nelemans, FA1
Pisciotta, AV1
Rose, MS1
Leahy, MF1
Stevens, A1
Black, PJ1
Barkhan, P1
Müller, WH1
Tanner, E1
Kouvalainen, K1
Pretty, HM1
Gosselin, G1
Colpron, G1
Long, LA1

Reviews

2 reviews available for aspirin and Agranulocytosis

ArticleYear
Use of antipyretic analgesics in the pediatric patient.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic

1983
Idiosyncratic hematologic reactions to drugs.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspir

1974

Other Studies

16 other studies available for aspirin and Agranulocytosis

ArticleYear
Mast cell activation syndrome masquerading as agranulocytosis.
    Military medicine, 2012, Volume: 177, Issue:1

    Topics: Agranulocytosis; Aspirin; Comorbidity; Diagnosis, Differential; Humans; Male; Mastocytosis, Systemic

2012
[THERAPEUTIC COMPLICATIONS OF ANALGESIC MEDICATIONS].
    Concours medical, 1964, Nov-14, Volume: 86

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Anemia; Anemia, Hemolytic; Aspirin; Drug Hypersensitivity;

1964
The combined effect of viruses and drugs in drug-induced diseases.
    Medical hypotheses, 1984, Volume: 14, Issue:3

    Topics: Agranulocytosis; Ampicillin; Aspirin; Drug Hypersensitivity; Humans; Infectious Mononucleosis; Reye

1984
Presumed analgesic-induced agranulocytosis.
    East African medical journal, 1983, Volume: 60, Issue:4

    Topics: Acetaminophen; Agranulocytosis; Analgesics; Aspirin; Dipyrone; Humans; Phenacetin

1983
[Benefit-risk considerations in metamizole treatment. Rational recommendations for indications and contra-indications according to current knowledge].
    Fortschritte der Medizin, 1982, Apr-15, Volume: 100, Issue:14

    Topics: Acetaminophen; Agranulocytosis; Aminopyrine; Anaphylaxis; Aspirin; Dipyrone; Humans; Injections, Int

1982
Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:5

    Topics: Agranulocytosis; Arachidonic Acids; Aspirin; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocy

1980
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female;

1980
Neutropenia with ticlopidine plus aspirin.
    Lancet (London, England), 1997, Feb-15, Volume: 349, Issue:9050

    Topics: Agranulocytosis; Aspirin; Coronary Disease; Humans; Monitoring, Physiologic; Neutropenia; Platelet A

1997
[Diagnostic problems in drug hypersensitivity].
    Anasthesiologische und intensivmedizinische Praxis, 1977, Volume: 14, Issue:1

    Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H

1977
Drug allergy.
    Southern medical journal, 1971, Volume: 64, Issue:1

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Aspirin; Asthma; Dermatitis, Contact; Drug

1971
[Medicamentous agranulocytosis as a manifestation of drug induced disease].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:1

    Topics: Adult; Agranulocytosis; Aminopyrine; Aspirin; Chloramphenicol; Drug-Related Side Effects and Adverse

1974
[Analgesics in dentistry].
    Nederlands tijdschrift voor tandheelkunde, 1972, Volume: 79, Issue:2

    Topics: Acetanilides; Agranulocytosis; Analgesics; Anesthesia, Dental; Aspirin; Blood Coagulation; Caffeine;

1972
The bone marrow during recovery from drug induced agranulocytosis.
    Guy's Hospital reports, 1972, Volume: 121, Issue:2

    Topics: Agranulocytosis; Analgesics; Aspirin; Azepines; Bone Marrow; Bone Marrow Cells; Bone Marrow Examinat

1972
[Gold therapy and agranulocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Aug-01, Volume: 28, Issue:15

    Topics: Adult; Agranulocytosis; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspir

1973
[Treatment of fever in childhood].
    Duodecim; laaketieteellinen aikakauskirja, 1974, Volume: 90, Issue:2

    Topics: Agranulocytosis; Aminopyrine; Aspirin; Child; Child, Preschool; Fever; Humans

1974
Agranulocytosis: a report of 30 cases.
    Canadian Medical Association journal, 1965, Nov-13, Volume: 93, Issue:20

    Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Aspirin; Bone Marrow; Bone Marrow Examination; Chlorproma

1965