Page last updated: 2024-10-23

aspirin and Agnogenic Myeloid Metaplasia

aspirin has been researched along with Agnogenic Myeloid Metaplasia in 29 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
" As compared with hydroxyurea plus aspirin, anagrelide plus aspirin was associated with increased rates of arterial thrombosis (P=0."5.11Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. ( Bareford, D; Buck, G; Campbell, PJ; East, CL; Green, AR; Grigg, AP; Harrison, CN; Reilly, JT; Revell, P; van der Walt, JD; Wheatley, K; Wilkins, BS; Woodcock, BE, 2005)
" An algorithm for the treatment of patients with erythremia is proposed along with recommendations on the use of aspirin, hydroxyurea, alpha-interpheron, and imatinib."4.88[True polycythemia: current views of pathogenesis, diagnostics and treatment]. ( Bakhteeva, TD; Kalinkina, NV; Skliannaia, EV; Taradin, GG; Vatutin, NT, 2012)
" Randomized studies have shown that the risk of thrombosis was significantly reduced in ET with the use of hydroxyurea (HU) and in PV with the use of chlorambucil or 32P."4.80Treatment of polycythaemia vera and essential thrombocythaemia. ( Silverstein, MN; Tefferi, A, 1998)
"The pregnancy was uneventful."2.55Primary myelofibrosis and pregnancy outcomes after low molecular-weight heparin administration: A case report and literature review. ( Bohîlţea, RE; Cîrstoiu, MM; Dimitriu, M; Ionescu, CA; Niculescu-Mizil, E; Turcan, N; Vlădăreanu, AM; Voican, I, 2017)
"Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms, respectively characterized by erythrocytosis and thrombocytosis."2.52Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2015)
"Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by sustained thrombocytosis, bone marrow megakaryocytic hyperplasia and an increased risk of thrombosis and hemorrhage."2.49[Treatment of essential thrombocythemia]. ( Alvarez-Larrán, A; Besses, C; Cervantes, F, 2013)
"Risk of thrombosis is higher in JAK2-mutated ET."1.51Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019)
"Polycythemia Vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus, and risk of leukemic or fibrotic transformation."1.46Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management. ( Barbui, T; Tefferi, A, 2017)
"Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons."1.42Management of myelofibrosis during pregnancy: a case report. ( Marisavljević, D; Marković, O; Terzić, T; Tukić, L; Zivković, R, 2015)
"A 20-year-old male with chronic myelogenous leukemia (CML) and severe bone marrow fibrosis underwent splenectomy, then ablative chemotherapy, followed by bone marrow transplantation from a histocompatible sister."1.27The reversal of myelofibrosis associated with chronic myelogenous leukemia after allogeneic bone marrow transplantation. ( Braylan, RC; Elfenbein, GJ; Jones, J; Oblon, DJ; Weiner, RS, 1983)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.69)18.7374
1990's2 (6.90)18.2507
2000's7 (24.14)29.6817
2010's9 (31.03)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Goulart, H1
Mascarenhas, J1
Tremblay, D1
Mora, B1
Passamonti, F1
Loscocco, GG1
Antonioli, E1
Romano, I1
Vergoni, F1
Rotunno, G1
Mannelli, F1
Guglielmelli, P2
Vannucchi, AM3
Gangat, N1
Al-Kali, A1
Wolanskyj-Spinner, AP1
Camoriano, J1
Patnaik, MM1
Pardanani, A1
Hanson, CA1
Tefferi, A5
Choi, HS1
Hong, J1
Hwang, SM1
Lee, JH1
Ma, Y1
Kim, SA1
Lee, JY1
Lee, JO1
Bang, SM1
Bohîlţea, RE1
Cîrstoiu, MM1
Ionescu, CA1
Niculescu-Mizil, E1
Vlădăreanu, AM1
Voican, I1
Dimitriu, M1
Turcan, N1
Barbui, T7
Alvarez-Larrán, A1
Cervantes, F2
Besses, C1
Pecci, A1
Croci, G1
Balduini, CL1
Boveri, E1
Yoshimoto, G1
Miyamoto, T1
Zivković, R1
Marković, O1
Marisavljević, D1
Terzić, T1
Tukić, L1
Beer, PA1
Green, AR3
Vatutin, NT1
Taradin, GG1
Bakhteeva, TD1
Kalinkina, NV1
Skliannaia, EV1
LEVRAT, M1
MOREL, P1
DEVIC, M1
BRUN, F1
Harrison, CN3
Campbell, PJ2
Buck, G2
Wheatley, K2
East, CL2
Bareford, D2
Wilkins, BS2
van der Walt, JD1
Reilly, JT1
Grigg, AP1
Revell, P1
Woodcock, BE1
Finazzi, G3
Di Nisio, M1
Di Gennaro, L1
Borrelli, G1
Landolfi, R2
Leone, G1
Marfisi, R1
Porreca, E1
Ruggeri, M1
Rutjes, AW1
Tognoni, G1
Marchioli, R2
Erber, WN1
Paul, B1
Viero, P1
Cortelazzo, S1
Bassan, R1
Ireland, H1
Lane, DA1
Wolff, S1
Foadi, M1
Oblon, DJ1
Elfenbein, GJ1
Braylan, RC1
Jones, J1
Weiner, RS1
Michiels, JJ1
Kutti, J1
Stark, P1
Bazzan, M1
Gugliotta, L1
Griesshammer, M1
van Genderen, PJ1
Brière, J1
Kiladjian, JJ1
Berlin, NI1
Pearson, TC1
Green, AC1
Fruchtmann, SM1
Silver, RT1
Hansmann, E1
Wehmeier, A1
Lengfelder, E1
Kvasnicka, HM1
Hasselbalch, H1
Thiele, J1
Silverstein, MN1
Randi, ML1
Rossi, C1
Fabris, F1
Girolami, A1
Hansen, MS1
Christensen, BE1
Jønsson, V1
Smelt, AH1
van der Meer, FJ1
Meinders, AE1

Reviews

11 reviews available for aspirin and Agnogenic Myeloid Metaplasia

ArticleYear
Low-risk polycythemia vera and essential thrombocythemia: management considerations and future directions.
    Annals of hematology, 2022, Volume: 101, Issue:5

    Topics: Aspirin; Humans; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Quality of

2022
SOHO State of the Art Updates and Next Questions | Polycythemia Vera: Is It Time to Rethink Treatment?
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:2

    Topics: Aspirin; Humans; Hydroxyurea; Janus Kinase 2; Middle Aged; Polycythemia Vera; Primary Myelofibrosis;

2023
Primary myelofibrosis and pregnancy outcomes after low molecular-weight heparin administration: A case report and literature review.
    Medicine, 2017, Volume: 96, Issue:46

    Topics: Adult; Aspirin; Cesarean Section; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heparin, L

2017
[Treatment of essential thrombocythemia].
    Medicina clinica, 2013, Sep-21, Volume: 141, Issue:6

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progress

2013
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy,

2014
Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Disease Management; Humans; Hydroxyurea; Janus Kinas

2015
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyu

2009
[True polycythemia: current views of pathogenesis, diagnostics and treatment].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Age Factors; Algorithms; Antineoplastic Agents; Aspirin; Benzamides; Combined Modality Therapy; Hema

2012
Diagnosis, pathogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and essential megakaryocytic granulocytic metaplasia and myelofibrosis.
    The Netherlands journal of medicine, 1999, Volume: 54, Issue:2

    Topics: Aspirin; Bone Marrow; Bone Marrow Transplantation; Diagnosis, Differential; Follow-Up Studies; Granu

1999
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; In

1998
Current trends in essential thrombocythaemia.
    British journal of haematology, 2002, Volume: 117, Issue:4

    Topics: Acute Disease; Aspirin; Bone Marrow Examination; Clone Cells; Dosage Compensation, Genetic; Heparin,

2002

Trials

2 trials available for aspirin and Agnogenic Myeloid Metaplasia

ArticleYear
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Female; F

2005
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
    Blood, 2008, Jan-01, Volume: 111, Issue:1

    Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematolo

2008

Other Studies

16 other studies available for aspirin and Agnogenic Myeloid Metaplasia

ArticleYear
Lenalidomide: A double-edged sword for concomitant multiple myeloma and post-essential thrombocythemia myelofibrosis.
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bone Marrow; Calreticulin; Dexamethas

2021
Pregnancy in patients with myelofibrosis: Mayo-Florence series of 24 pregnancies in 16 women.
    British journal of haematology, 2021, Volume: 195, Issue:1

    Topics: Abortion, Habitual; Adult; Anticoagulants; Aspirin; Diabetes, Gestational; Female; Fetal Death; Hemo

2021
Evaluation of the need for cytoreduction and its potential carcinogenicity in children and young adults with myeloproliferative neoplasms.
    Annals of hematology, 2021, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Aspirin; Child; Female; Fibrinolytic Agents; Follow-Up Stu

2021
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Cutaneous involvement by post-polycythemia vera myelofibrosis.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Aged; Aspirin; Biopsy; Cell Lineage; Disease Progression; Drug Therapy, Combination; Fibrosis; Hemat

2014
Management of myelofibrosis during pregnancy: a case report.
    Vojnosanitetski pregled, 2015, Volume: 72, Issue:4

    Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrinolytic

2015
Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Aspirin; Calreticulin; Diagnosis, Differential; Erythropoietin; Humans; Hydroxyurea; Interferon-alph

2017
[Aleukemic megakaryocytic myelosis. Possible effect of massive ingestion of aspirin during ten years].
    Lyon medical, 1951, Jun-24, Volume: 184, Issue:25

    Topics: Aspirin; Eating; Leukemia; Primary Myelofibrosis

1951
When and how to treat essential thrombocythemia.
    The New England journal of medicine, 2005, Jul-07, Volume: 353, Issue:1

    Topics: Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxyurea; Leukemia

2005
The haematocrit and platelet target in polycythemia vera.
    British journal of haematology, 2007, Volume: 136, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Progression; Female; Follow-Up Studi

2007
Effect of aspirin on platelet 5-hydroxytryptamine and beta-thromboglobulin plasma levels in patients with myeloproliferative diseases.
    Thrombosis and haemostasis, 1982, Oct-29, Volume: 48, Issue:2

    Topics: Adult; Aged; Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Platelets; Female; Humans; Leukemi

1982
In vivo platelet release in myeloproliferative disorders.
    Thrombosis and haemostasis, 1982, Aug-24, Volume: 48, Issue:1

    Topics: Aged; Aspirin; beta-Thromboglobulin; Blood Platelets; Fibrinopeptide A; Fibrinopeptide B; Humans; Mi

1982
The reversal of myelofibrosis associated with chronic myelogenous leukemia after allogeneic bone marrow transplantation.
    Experimental hematology, 1983, Volume: 11, Issue:7

    Topics: Adult; Allopurinol; Aspirin; Bone Marrow; Bone Marrow Transplantation; Busulfan; Drug Therapy, Combi

1983
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free

2000
The effect of acetyl salicylic acid and dipyridamole on thromboembolic complications in splenectomized patients with myelofibrosis.
    Scandinavian journal of haematology, 1979, Volume: 23, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Cell Survival; Dipyridamole; Drug Therapy, Combination; Female; Huma

1979
Erythromelalgia in a patient with myelofibrosis.
    The Netherlands journal of medicine, 1988, Volume: 33, Issue:5-6

    Topics: Aged; Aspirin; Erythromelalgia; Humans; Male; Platelet Count; Primary Myelofibrosis

1988