aspirin has been researched along with Acute Promyelocytic Leukemia in 3 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous experiments have shown that a variety of agents that interfere with the activity of the transcription factor NF-kB significantly enhanced the differentiation of HL-60 leukemia cells when combined with low levels of the monocytic/macrophagic differentiating agent vitamin D3." | 1.30 | Induction of the differentiation of HL-60 promyelocytic leukemia cells by nonsteroidal anti-inflammatory agents in combination with low levels of vitamin D3. ( Sartorelli, AC; Sokoloski, JA, 1998) |
| "Evidence of disseminated intravascular coagulation was found in 13 (62%) of the 21 cases at diagnosis." | 1.28 | Acute promyelocytic leukemia: impact of hemorrhagic complications on response to induction chemotherapy and survival. ( Hess, CE; Humphries, JE; Stewart, FM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jamshidi, F | 1 |
| Zhang, J | 1 |
| Harrison, JS | 1 |
| Wang, X | 1 |
| Studzinski, GP | 1 |
| Sokoloski, JA | 1 |
| Sartorelli, AC | 1 |
| Humphries, JE | 1 |
| Hess, CE | 1 |
| Stewart, FM | 1 |
3 other studies available for aspirin and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Induction of differentiation of human leukemia cells by combinations of COX inhibitors and 1,25-dihydroxyvitamin D3 involves Raf1 but not Erk 1/2 signaling.
Topics: Aspirin; Calcitriol; Cell Differentiation; Cyclooxygenase Inhibitors; G1 Phase; HL-60 Cells; Humans; | 2008 |
Induction of the differentiation of HL-60 promyelocytic leukemia cells by nonsteroidal anti-inflammatory agents in combination with low levels of vitamin D3.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Differentiation; Cholecalciferol; Drug Intera | 1998 |
Acute promyelocytic leukemia: impact of hemorrhagic complications on response to induction chemotherapy and survival.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Blood Cell Count; | 1990 |